nifedipine has been researched along with Cardiac Remodeling, Ventricular in 11 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The combination with olmesartan and nifedipine, as well as a monotherapy with olmesartan, exerts preferable cardioprotection in diabetic mice exposed to recurrent hypoxia." | 7.76 | Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice. ( Hayashi, T; Kitada, K; Kitaura, Y; Matsumoto, C; Matsumura, Y; Miyamura, M; Mori, T; Okada, Y; Sohmiya, K; Ukimura, A; Yamashita, C; Yoshioka, T, 2010) |
| "Meanwhile, the left ventricular remodeling, 24-hours levels of urinary microalbumin, endothelial dysfunction, and arterial stiffness were all significantly improved compared with that of the baseline and the nifedipine group (all P < ." | 6.90 | Effects of allisartan isoproxil on blood pressure and target organ injury in patients with mild to moderate essential hypertension. ( Chen, SB; Dong, Y; Li, YM; Liu, JX; Shi, R; Yang, GH; Zhang, JQ; Zhou, X, 2019) |
| "Hypertensive patients with coronary artery disease were randomly assigned to the nifedipine retard (n = 108) or ACE inhibitors groups (n = 102) and treated for 3 years." | 5.14 | Reverse remodeling and improved function by antihypertensive treatment in hypertensive patients with coronary artery disease. ( Haze, K; Hirayama, A; Hosoda, S; Iwanaga, Y; Kawai, C; Kodama, K; Nishio, R; Nonogi, H; Sumiyoshi, T; Yui, N; Yui, Y, 2010) |
| "The aim of this study was to evaluate the effect of the calcium antagonist Nifedipine GITS in a double-blind, randomized comparison with the diuretic hydrochlorothiazide (HCTZ) on reduction of left ventricular (LV) mass and minimal vascular resistance in a group of essential hypertensives with left ventricular hypertrophy (LVH)." | 5.08 | Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients. ( Agabiti-Rosei, E; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R, 1998) |
| "The combination with olmesartan and nifedipine, as well as a monotherapy with olmesartan, exerts preferable cardioprotection in diabetic mice exposed to recurrent hypoxia." | 3.76 | Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice. ( Hayashi, T; Kitada, K; Kitaura, Y; Matsumoto, C; Matsumura, Y; Miyamura, M; Mori, T; Okada, Y; Sohmiya, K; Ukimura, A; Yamashita, C; Yoshioka, T, 2010) |
| "Meanwhile, the left ventricular remodeling, 24-hours levels of urinary microalbumin, endothelial dysfunction, and arterial stiffness were all significantly improved compared with that of the baseline and the nifedipine group (all P < ." | 2.90 | Effects of allisartan isoproxil on blood pressure and target organ injury in patients with mild to moderate essential hypertension. ( Chen, SB; Dong, Y; Li, YM; Liu, JX; Shi, R; Yang, GH; Zhang, JQ; Zhou, X, 2019) |
| "Treatment with Candesartan (2mg/kg per day) could effectively downregulate Smad3 and fibronectin accompanied by upregulating of Smad7." | 1.38 | Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression. ( Li, H; Liu, X; Wang, S; Yu, H; Zhao, G, 2012) |
| "These diseases induce cardiac hypertrophy and increases in [Ca(2+)] are known to be an essential proximal signal for activation of hypertrophic genes." | 1.38 | Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling. ( Barr, LA; Berretta, RM; Gao, H; Houser, SR; Kubo, H; Makarewich, CA; Molkentin, JD; Wang, F; Wang, W; Zhang, H, 2012) |
| "The treatment with nifedipine in the CIH group attenuated blood pressure (159+/-2 mm Hg; P<0." | 1.35 | Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels. ( Gozal, D; Gu, Y; Nozdrachev, AD; Ortines, RV; Prabhu, SD; Soukhova-O'Hare, GK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JQ | 1 |
| Yang, GH | 1 |
| Zhou, X | 1 |
| Liu, JX | 1 |
| Shi, R | 1 |
| Dong, Y | 1 |
| Chen, SB | 1 |
| Li, YM | 1 |
| Yamada, T | 1 |
| Nagata, K | 1 |
| Cheng, XW | 1 |
| Obata, K | 1 |
| Saka, M | 1 |
| Miyachi, M | 1 |
| Naruse, K | 1 |
| Nishizawa, T | 1 |
| Noda, A | 1 |
| Izawa, H | 1 |
| Kuzuya, M | 1 |
| Okumura, K | 1 |
| Murohara, T | 1 |
| Yokota, M | 1 |
| Yui, Y | 1 |
| Kodama, K | 1 |
| Hirayama, A | 1 |
| Nishio, R | 1 |
| Iwanaga, Y | 1 |
| Nonogi, H | 1 |
| Haze, K | 1 |
| Sumiyoshi, T | 1 |
| Yui, N | 1 |
| Hosoda, S | 1 |
| Kawai, C | 1 |
| Yamashita, C | 1 |
| Hayashi, T | 1 |
| Mori, T | 1 |
| Matsumoto, C | 1 |
| Kitada, K | 1 |
| Miyamura, M | 1 |
| Sohmiya, K | 1 |
| Ukimura, A | 1 |
| Okada, Y | 1 |
| Yoshioka, T | 1 |
| Kitaura, Y | 1 |
| Matsumura, Y | 1 |
| Yu, H | 1 |
| Zhao, G | 1 |
| Li, H | 1 |
| Liu, X | 1 |
| Wang, S | 1 |
| Gao, H | 1 |
| Wang, F | 1 |
| Wang, W | 1 |
| Makarewich, CA | 1 |
| Zhang, H | 1 |
| Kubo, H | 1 |
| Berretta, RM | 1 |
| Barr, LA | 1 |
| Molkentin, JD | 1 |
| Houser, SR | 1 |
| Boydak, B | 1 |
| Nalbantgil, S | 1 |
| Yilmaz, H | 1 |
| Zoghi, M | 1 |
| Ozerkan, F | 1 |
| Nalbantgil, I | 1 |
| Onder, R | 1 |
| Bagate, K | 1 |
| Meiring, JJ | 1 |
| Gerlofs-Nijland, ME | 1 |
| Cassee, FR | 1 |
| Wiegand, H | 1 |
| Osornio-Vargas, A | 1 |
| Borm, PJ | 1 |
| Soukhova-O'Hare, GK | 1 |
| Ortines, RV | 1 |
| Gu, Y | 1 |
| Nozdrachev, AD | 1 |
| Prabhu, SD | 1 |
| Gozal, D | 1 |
| Agabiti-Rosei, E | 1 |
| Zulli, R | 1 |
| Muiesan, ML | 1 |
| Salvetti, M | 1 |
| Rizzoni, D | 1 |
| Corbellini, C | 1 |
| Monteduro, C | 1 |
| Aimond, F | 1 |
| Alvarez, JL | 1 |
| Rauzier, JM | 1 |
| Lorente, P | 1 |
| Vassort, G | 1 |
4 trials available for nifedipine and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Effects of allisartan isoproxil on blood pressure and target organ injury in patients with mild to moderate essential hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Endothelium, V | 2019 |
Reverse remodeling and improved function by antihypertensive treatment in hypertensive patients with coronary artery disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Coronary Ar | 2010 |
The effect of combination therapy on regression of left ventricular hypertrophy in cases with hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Ch | 2004 |
Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepa | 1998 |
7 other studies available for nifedipine and Cardiac Remodeling, Ventricular
| Article | Year |
|---|---|
Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Collagen; Disease Models, Animal; Fibros | 2009 |
Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice.
Topics: Animals; Diabetes Mellitus, Type 2; Dietary Fats; Drug Therapy, Combination; Hypoxia; Imidazoles; Ma | 2010 |
Candesartan antagonizes pressure overload-evoked cardiac remodeling through Smad7 gene-dependent MMP-9 suppression.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Cells, Culture | 2012 |
Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.
Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Ca | 2012 |
Ambient particulate matter affects cardiac recovery in a Langendorff ischemia model.
Topics: Air Pollutants; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Circulation; | 2006 |
Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Ty | 2008 |
Ionic basis of ventricular arrhythmias in remodeled rat heart during long-term myocardial infarction.
Topics: Action Potentials; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Analysis of Variance; Animal | 1999 |