Page last updated: 2024-11-01

nifedipine and Cardiac Hypertrophy

nifedipine has been researched along with Cardiac Hypertrophy in 91 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
"Sixteen patients with severe hypertension were treated for 1 year with extended release nifedipine, during which time serial changes in left ventricular mass index and associated alterations in left ventricular systolic function, left ventricular filling, plasma renin activity, atrial natriuretic peptide and catecholamines were evaluated."9.07Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991)
"The effects of two antihypertensive agents, nifedipine (N) and captopril (C), on left ventricular (LV) mass and volume were studied in 16 patients with essential hypertension (8 treated with N and 8 with C for 6 months) by means of a complete M-mode echocardiogram monitored by two-dimensional echocardiography."9.06Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril. ( Accardi, R; Arcaro, G; Covi, G; Lechi, A; Sheiban, I; Zenorini, C, 1987)
"Nifedipine was used successfully in nine patients with refractory hypertension and left ventricular hypertrophy who had symptoms of congestive heart failure despite preserved left ventricular systolic function."7.67Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function. ( Dzau, VJ; Given, BD; Lee, TH; Stone, PH, 1985)
"The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age."7.67Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987)
"We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia."7.67Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986)
" It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency."5.28Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990)
"Nifedipine did not produce any depression of contractile and pump functions of the heart."5.28[Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects]. ( Bobrov, VA; Konoshevich, SN, 1989)
"Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis."5.27The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988)
"Sixteen patients with severe hypertension were treated for 1 year with extended release nifedipine, during which time serial changes in left ventricular mass index and associated alterations in left ventricular systolic function, left ventricular filling, plasma renin activity, atrial natriuretic peptide and catecholamines were evaluated."5.07Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991)
"The effects of two antihypertensive agents, nifedipine (N) and captopril (C), on left ventricular (LV) mass and volume were studied in 16 patients with essential hypertension (8 treated with N and 8 with C for 6 months) by means of a complete M-mode echocardiogram monitored by two-dimensional echocardiography."5.06Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril. ( Accardi, R; Arcaro, G; Covi, G; Lechi, A; Sheiban, I; Zenorini, C, 1987)
"The calcium channel blocker (CCB), nifedipine, is a more effective treatment for early- than late-stage cardiac hypertrophy."3.83Early administration of nifedipine protects against angiotensin II-induced cardiomyocyte hypertrophy through regulating CaMKII-SERCA2a pathway and apoptosis in rat cardiomyocytes. ( Du, YM; Luo, J; Zhang, WD, 2016)
" The pharmacokinetics of verapamil and of one of its metabolites, norverapamil, is changed after multiple oral dosing as has been described in patients with supraventricular tachyarrhythmias, angina pectoris or in patients with essential hypertension."3.76Pharmacokinetics of calcium channel blocking agents. ( Anderson, P, 1986)
"The three treatments regressed cardiac hypertrophy and normalized sodium/hydrogen ion exchange exchange activity in SHR, and losartan was the most effective treatment for reversing cardiac hypertrophy, despite producing effects on blood pressure and sodium/hydrogen exchange activity similar to that of other antihypertensive drugs."3.71Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats. ( Alvarez, BV; Cingolani, HE; De Hurtado, MC; Ennis, IL, 2002)
"Angiotensin II plays an important role in the development of cardiac hypertrophy."3.70Effects of taurine on signal transduction steps induced during hypertrophy of rat heart myocytes. ( Rao, MR; Tao, L, 1998)
" Endothelin-1 (ET-1), one of the endogenous pathological humoral factors of cardiovascular diseases such as hypertension and heart failure, has a strong vasoconstrictive action and could induce hypertension and cardiac hypertrophy."3.70Possible involvement of endothelin-1 in cardioprotective effects of benidipine. ( Akashi, T; Harada, M; Hosoya, T; Ikeda, K; Nakagawa, O; Nakao, K; Tojo, K; Tokudome, G, 2000)
" Mibefradil treatment resulted in lower blood pressure, reduced cardiac hypertrophy, near-normal structure of conduit and small arteries and lower endothelin-1 mRNA abundance."3.69Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats. ( Li, JS; Schiffrin, EL; Sventek, P, 1996)
"The aim of the present study was to define the protective effects of verapamil and nifedipine on mechanical performance and energy and substrate metabolism of the postischemically reperfused myocardium in a chronic pressure overload cardiac hypertrophy model."3.68Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy. ( Buser, PT; Higgins, CB; Wagner, S; Wikman-Coffelt, J; Wu, S, 1991)
"Fourteen patients with previously untreated essential hypertension and left ventricular hypertrophy were treated with a fixed-dose combination of acebutolol 200 mg and nifedipine 20 mg once daily for a followup of 25."3.67Regression of left ventricular hypertrophy by acebutolol and nifedipine. ( Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U, 1989)
" On this basis, functional and therapeutical regimen of regression of cardiac hypertrophy (prazosin, clonidine, nifedipine) are analyzed in concentric as well as in excentric hypertrophy in patients with arterial hypertension."3.67[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects]. ( Strauer, BE, 1985)
"We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia."3.67Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986)
"The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age."3.67Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987)
"Nifedipine was used successfully in nine patients with refractory hypertension and left ventricular hypertrophy who had symptoms of congestive heart failure despite preserved left ventricular systolic function."3.67Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function. ( Dzau, VJ; Given, BD; Lee, TH; Stone, PH, 1985)
" Patients received a daily oral dosage of either 4 to 8 mg of perindopril or 40 to 80 mg of nifedipine in slow-release form."2.67Relation of regression of left ventricular hypertrophy to changes in ambulatory blood pressure after long-term therapy with perindopril versus nifedipine. ( Gotzen, R; Lenz, T; Liederwald, K; Meyer-Sabellek, W; Schulte, KL; van Gemmeren, D, 1992)
" Twenty-one patients with concentric LVH (thickness of interventricular septum, IVS, and left posterior wall, LPW, above 11 mm) were given a 2D and M-mode echocardiogram before (pre) and 12 and 24 weeks, respectively, after therapy was initiated (mean oral cl dosage 150 micrograms; nf, 30 mg/day)."2.66Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients. ( Brückner, S; Kleine, P; Meissner, E; von Bruchhausen, V, 1987)
"Verapamil was discontinued in 2 patients who developed severe dyspnea at rest after 3-4 days of continued oral treatment."2.65Clinical use of calcium channel blockers as ventricular unloading agents. ( Agostoni, PG; Cipolla, C; Fabbiocchi, F; Guazzi, MD; Pepi, M; Sganzerla, P, 1983)
" This is a significant limitation because sustained changes in blood pressure are often accompanied by changes in heart rate and together can lead to cardiac hypertrophy and myocardial degeneration in animals, and major adverse cardiovascular events (MACE) in humans."1.43Natriuretic Peptides as Cardiovascular Safety Biomarkers in Rats: Comparison With Blood Pressure, Heart Rate, and Heart Weight. ( Engle, SK; Watson, DE, 2016)
"She had clinical features of systemic sclerosis (SSc) which was subsequently confirmed on further workup."1.39Recurrent cardiac tamponade in a young woman. ( Itolikar, M; Itolikar, SM; Phatak, S; Salagre, S, 2013)
"These diseases induce cardiac hypertrophy and increases in [Ca(2+)] are known to be an essential proximal signal for activation of hypertrophic genes."1.38Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling. ( Barr, LA; Berretta, RM; Gao, H; Houser, SR; Kubo, H; Makarewich, CA; Molkentin, JD; Wang, F; Wang, W; Zhang, H, 2012)
"Regression of cardiac hypertrophy was accompanied by a 50% to 300% increase in DNA fragmentation and a >20% reduction in DNA synthesis, resulting in a >20% reduction in cardiac DNA content after 4 weeks."1.30Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity. ( Dam, TV; deBlois, D; Hamet, P; Moreau, P; Tea, BS, 1999)
" Co-administration with propranolol markedly decreased the heart rate, but little affected the heart weight, suggesting changes in the heart rate during the long-term administration of KW-3049 did not largely affect cardiac hypertrophy."1.29Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats. ( Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H, 1993)
"Concomitantly, cardiac hypertrophy was attenuated in the treated group compared with the placebo group (heart-to-body weight ratios of 4."1.28Vascular injury: mechanisms and manifestations. ( Nayler, WG, 1991)
"Nifedipine did not produce any depression of contractile and pump functions of the heart."1.28[Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects]. ( Bobrov, VA; Konoshevich, SN, 1989)
" It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency."1.28Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990)
"Amlodipine is a long-acting dihydropyridine calcium antagonist with vascular selectivity."1.28Vascular and myocardial effects of amlodipine: an overview. ( Gu, XH; Nayler, WG, 1991)
"Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis."1.27The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988)
"Renal function and salt and water turnover were studied in SHR during acute and chronic administration of felodipine, which is an efficient antihypertensive vasodilating Ca2+ antagonist."1.27Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR. ( Di Bona, GF; Ljung, B; Nordlander, M; Thorén, P; Yao, T, 1985)
"Nifedipine therapy was associated with an improved LV filling in nearly all cases of HCM and HHD, and in some cases of IHD."1.27[Stress pulsed Doppler echocardiography in the evaluation of diastolic left ventricular function]. ( Asai, M; Fukuda, N; Ishimoto, T; Mori, H; Niki, T; Ohkushi, H; Oki, T; Taoka, M; Tominaga, T, 1985)
"In hypertensive cardiac hypertrophy, the elevated coronary perfusion pressure compensates importantly for the raised coronary resistance."1.27Electrocardiographic alterations suggestive of myocardial injury elicited by rapid pressure lowering in hypertension. ( Alimento, M; Guazzi, MD; Maltagliati, A; Pepi, M; Tosi, E, 1988)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199047 (51.65)18.7374
1990's32 (35.16)18.2507
2000's4 (4.40)29.6817
2010's8 (8.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Itolikar, SM1
Salagre, S1
Phatak, S1
Itolikar, M1
Engle, SK1
Watson, DE1
Luo, J1
Zhang, WD1
Du, YM1
Luo, Q1
Xuan, WL1
Xi, F1
Liao, YL1
Kitakaze, M1
Veeramani, C1
Aristatle, B1
Pushpavalli, G1
Pugalendi, KV1
Ago, T1
Yang, Y1
Zhai, P1
Sadoshima, J1
Gao, H1
Wang, F1
Wang, W1
Makarewich, CA1
Zhang, H1
Kubo, H1
Berretta, RM1
Barr, LA1
Molkentin, JD1
Houser, SR1
Zhang, ZJ1
Fan, YF1
Zhang, ZY1
Xie, PY1
Fang, HC1
Su, YS1
Massie, BM1
Hirsch, AT1
Inouye, IK1
Tubau, JF1
Opie, LH2
Senn, M1
Hess, OM1
Krayenbühl, HP1
Wise, JR1
Guazzi, MD5
Cipolla, C1
Sganzerla, P1
Agostoni, PG2
Fabbiocchi, F1
Pepi, M4
Loaldi, A1
Fiorentini, C1
Grazi, S1
Della Bella, P1
Dukes, ID1
Vaughan Williams, EM1
Oemar, H1
Gutiérrez Palau, L1
Bolaños Miñambres, IF1
Lundin, SA1
Hallbäck-Nordlander, MI1
Narita, M1
Kurihara, T1
Murano, K1
Usami, M1
Honda, M1
Kanao, K1
Strauer, BE7
Atef Mahmoud, M1
Bayer, F1
Bohn, I1
Motz, U1
Ewy, GA1
Békés, M1
Cserhalmi, L1
Glavanov, M1
Csukás, A1
Szilágyi, M1
Huszár, G1
Giudicelli, JF1
Freslon, JL1
Richer, C1
Hope, RR1
Lazzara, R1
Kato, Y1
Tanaka, H1
Saijyo, T1
Hattori, O1
Suzuki, K1
Hara, T1
Deguchi, T1
Matsubara, H1
Suzuki, J1
Inada, M1
Johnson, PL1
Bhattacharya, SK1
Li, JS1
Sventek, P1
Schiffrin, EL1
Gómez, AM1
Valdivia, HH1
Cheng, H1
Lederer, MR1
Santana, LF1
Cannell, MB1
McCune, SA1
Altschuld, RA1
Lederer, WJ1
Yamazaki, T2
Komuro, I2
Zou, Y2
Kudoh, S1
Shiojima, I1
Mizuno, T1
Hiroi, Y1
Nagai, R2
Yazaki, Y1
Rao, MR1
Tao, L1
Murphy, RJ1
Béliveau, L1
Gardiner, PF1
Calderone, A1
Tea, BS1
Dam, TV1
Moreau, P1
Hamet, P1
deBlois, D1
Kalliovalkama, J1
Kähönen, M1
Tolvanen, JP1
Wu, X1
Voipio, J1
Pekki, A1
Doris, PA1
Ylitalo, P1
Pörsti, I1
Ikeda, K1
Tojo, K1
Tokudome, G1
Akashi, T1
Hosoya, T1
Harada, M1
Nakagawa, O1
Nakao, K1
Nakagawa, K1
Yamada, H1
Iriguchi, N1
Toko, H1
Takano, H1
Akazawa, H1
Alvarez, BV1
Ennis, IL1
De Hurtado, MC1
Cingolani, HE1
Phillips, RA2
Ardeljan, M2
Shimabukuro, S2
Goldman, ME2
Garbowit, DL2
Eison, HB2
Krakoff, LR2
Schulte, KL1
Meyer-Sabellek, W1
Liederwald, K1
van Gemmeren, D1
Lenz, T1
Gotzen, R1
Nishimura, H1
Kubota, J1
Okabe, M1
Ueyama, M1
Kawamura, K1
Shigematsu, S1
Yamada, T1
Aizawa, T1
Takasu, N1
Shimizu, Z1
Otterstad, JE1
Froeland, G1
Wasenius Soeyland, AK1
Knutsen, KM1
Ekeli, T1
Callens-el Amrani, F1
Mayoux, E1
Mouas, C1
Clapier-Ventura, R1
Henzel, D1
Charlemagne, D1
Swynghedauw, B1
Cuspidi, C1
Sampieri, L1
Angioni, L1
Boselli, L1
Bragato, R1
Leonetti, G1
Zanchetti, A1
Clark, WA1
Rudnick, SJ1
LaPres, JJ1
Lesch, M1
Decker, RS1
Buser, PT1
Wagner, S1
Wu, S1
Higgins, CB1
Wikman-Coffelt, J1
Nayler, WG3
Ianovskiĭ, GV1
Golub', NS1
Vysotskaia, ZhM1
Stadniuk, LA1
Kovtun, LI1
Gu, XH1
Ivleva, AIa1
Demidenko, IV1
Krasnobaeva, GM1
Strugovshchikov, AN1
Moĭseev, VS1
Cai, B1
Sharaf el-Deane, MS1
Parker, BM1
Franz, IW5
Tönnesmann, U5
Behr, U5
Ketelhut, R5
Lee, RT1
Lord, CP1
Plappert, T1
Sutton, MS1
Rudzite, VK1
Vitols, AV1
Liepinja, DJ1
Silava, AK1
Viné, F1
Bourdon, JL1
Bragard, MF1
Hayashi, H1
Iwase, M1
Aoki, T1
Yokota, M1
Sau, F1
Seguro, C1
Pili, G1
Basciu, M1
Siddi, PP1
Tamponi, R1
Cherchi, A1
Mace, PJ1
Littler, WA2
Glover, DR1
Rowlands, DB1
Stallard, TJ1
Motz, W4
Sharma, RV1
Butters, CA1
Bhalla, RC1
Sheiban, I1
Arcaro, G1
Covi, G1
Accardi, R1
Zenorini, C1
Lechi, A1
Kleine, P1
Meissner, E1
von Bruchhausen, V1
Brückner, S1
Klepzig, M1
Matsubara, T1
Yamazoe, M1
Koike, T1
Izumi, T1
Shibata, A1
Linz, W1
Schölkens, BA1
Ganten, D1
Bestetti, RB1
Pinto, LZ1
Finzi, LA1
Secches, AL1
Bobrov, VA1
Konoshevich, SN1
Zähringer, J1
Stangl, E1
Danninger, B1
Aschauer, W1
Jennings, AA1
Jee, LD1
Smith, JA1
Commerford, PJ1
Nordlander, M1
Di Bona, GF1
Ljung, B1
Yao, T1
Thorén, P1
Asai, M1
Oki, T1
Ohkushi, H1
Ishimoto, T1
Tominaga, T1
Taoka, M1
Fukuda, N1
Niki, T1
Mori, H1
Michael, JR1
Kennedy, TP1
Buescher, P1
Farrukh, I1
Lodato, R1
Rock, PC1
Gottlieb, J1
Gurtner, G1
de la Monte, SM1
Hutchins, GM1
Anderson, P1
Bradley, AB1
Baim, DS1
Stasch, JP1
Kazda, S1
Hirth, C1
Morich, F1
Alimento, M2
Maltagliati, A2
Tosi, E1
Given, BD1
Lee, TH1
Stone, PH1
Dzau, VJ1
Bouthier, JD1
De Luca, N1
Safar, ME1
Simon, AC1

Reviews

5 reviews available for nifedipine and Cardiac Hypertrophy

ArticleYear
Calcium channel blockers as antihypertensive agents.
    The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A

    Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease;

1984
The clinical uses of calcium antagonists.
    Advances in internal medicine, 1982, Volume: 27

    Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel B

1982
Postinfarction cardiac dilatation. Is it modifiable?
    Chest, 1990, Volume: 97, Issue:2

    Topics: Animals; Captopril; Cardiomegaly; Humans; Myocardial Contraction; Myocardial Infarction; Nifedipine;

1990
Pharmacokinetics of calcium channel blocking agents.
    Acta pharmacologica et toxicologica, 1986, Volume: 58 Suppl 2

    Topics: Administration, Oral; Angina Pectoris; Atrial Fibrillation; Biological Availability; Cardiomegaly; C

1986
Measurement of coronary blood flow in man: methods and implications for clinical practice.
    Cardiovascular clinics, 1985, Volume: 15, Issue:1

    Topics: Amrinone; Angina Pectoris; Animals; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary V

1985

Trials

15 trials available for nifedipine and Cardiac Hypertrophy

ArticleYear
Calcium channel blockers as antihypertensive agents.
    The American journal of medicine, 1984, Oct-05, Volume: 77, Issue:4A

    Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease;

1984
Clinical use of calcium channel blockers as ventricular unloading agents.
    European heart journal, 1983, Volume: 4 Suppl A

    Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Top

1983
Calcium channel blocking agents.
    Medical times, 1981, Volume: 109, Issue:8

    Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Di

1981
[Acute action of nifedipine in patients with obstructive and nonobstructive asymmetrical septum hypertrophy (ASH)].
    Die Medizinische Welt, 1980, Sep-26, Volume: 31, Issue:39

    Topics: Adult; Cardiomegaly; Cardiomyopathy, Hypertrophic; Hemodynamics; Humans; Middle Aged; Nifedipine; Py

1980
Relation of regression of left ventricular hypertrophy to changes in ambulatory blood pressure after long-term therapy with perindopril versus nifedipine.
    The American journal of cardiology, 1992, Aug-15, Volume: 70, Issue:4

    Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Circadian Rhythm; Double-Blind M

1992
Changes in left ventricular dimensions and systolic function in 100 mildly hypertensive men during one year's treatment with atenolol vs. hydrochlorothiazide and amiloride (Moduretic): a double-blind, randomized study.
    Journal of internal medicine, 1992, Volume: 231, Issue:5

    Topics: Adult; Aged; Atenolol; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hydrochlorothiaz

1992
Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension.
    Journal of the American College of Cardiology, 1991, Volume: 17, Issue:7

    Topics: Atrial Natriuretic Factor; Cardiomegaly; Chlorthalidone; Delayed-Action Preparations; Echocardiograp

1991
[Regression of left ventricular hypertrophy in hypertensive patients under long-term therapy with antihypertensive agents].
    Deutsche medizinische Wochenschrift (1946), 1990, Apr-20, Volume: 115, Issue:16

    Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Female; Gallopamil; Humans; Hype

1990
Assessment of left ventricular function after sublingual administration of nifedipine in patients with moderate to severe hypertension.
    Cardiovascular drugs and therapy, 1990, Volume: 4 Suppl 5

    Topics: Administration, Sublingual; Adult; Blood Pressure; Cardiomegaly; Echocardiography; Echocardiography,

1990
[Electrocardiographic and echocardiographic changes during antihypertensive therapy].
    Cardiologia (Rome, Italy), 1990, Volume: 35, Issue:12

    Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidon

1990
Regression of left ventricular hypertrophy in hypertension: comparative effects of three different drugs.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 2

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Female; Humans; Hypert

1985
Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Adult; Blood Pressure; Captopril; Cardiomegaly; Echocardiography; Heart; Heart Rate; Humans; Hyperte

1987
Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 12

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clonidine; Echocardiography; Female; Heart; Heart Rate; H

1987
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
    Zeitschrift fur Kardiologie, 1989, Volume: 78 Suppl 5

    Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly;

1989
Pharmacokinetics of calcium channel blocking agents.
    Acta pharmacologica et toxicologica, 1986, Volume: 58 Suppl 2

    Topics: Administration, Oral; Angina Pectoris; Atrial Fibrillation; Biological Availability; Cardiomegaly; C

1986

Other Studies

73 other studies available for nifedipine and Cardiac Hypertrophy

ArticleYear
Recurrent cardiac tamponade in a young woman.
    BMJ case reports, 2013, Nov-29, Volume: 2013

    Topics: Adult; Cardiac Tamponade; Cardiomegaly; Cyclophosphamide; Female; Humans; Hypothyroidism; Nifedipine

2013
Natriuretic Peptides as Cardiovascular Safety Biomarkers in Rats: Comparison With Blood Pressure, Heart Rate, and Heart Weight.
    Toxicological sciences : an official journal of the Society of Toxicology, 2016, Volume: 149, Issue:2

    Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomegaly; Heart Rate; Indoles; M

2016
Early administration of nifedipine protects against angiotensin II-induced cardiomyocyte hypertrophy through regulating CaMKII-SERCA2a pathway and apoptosis in rat cardiomyocytes.
    Cell biochemistry and function, 2016, Volume: 34, Issue:3

    Topics: Angiotensin II; Animals; Apoptosis; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cardiomegaly

2016
[Antihypertrophic effect of dihydropyridines calcium channel blockers is dependent on their potential of blocking N-type calcium channel].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2010, Volume: 30, Issue:4

    Topics: Amlodipine; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Cardiomegaly; Dihydropyridi

2010
Antihypertensive efficacy of Melothria maderaspatana leaf extract on sham-operated and uninephrectomized DOCA-salt hypertensive rats.
    Journal of basic and clinical physiology and pharmacology, 2010, Volume: 21, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Cucurbitac

2010
Nifedipine inhibits cardiac hypertrophy and left ventricular dysfunction in response to pressure overload.
    Journal of cardiovascular translational research, 2010, Volume: 3, Issue:4

    Topics: Algorithms; Animals; Blood Pressure; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein

2010
Ca(2+) influx through L-type Ca(2+) channels and transient receptor potential channels activates pathological hypertrophy signaling.
    Journal of molecular and cellular cardiology, 2012, Volume: 53, Issue:5

    Topics: Animals; Calcineurin; Calcineurin Inhibitors; Calcium Channel Blockers; Calcium Channels, L-Type; Ca

2012
[Effects of rho-kinase inhibitor on cardiac hypertrophy of left ventricle in spontaneously hypertensive rats].
    Zhonghua yi xue za zhi, 2012, Dec-25, Volume: 92, Issue:48

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cardiomegaly; Heart Ventricles; Male; Nifedi

2012
Drugs and the heart. III. Calcium antagonists.
    Lancet (London, England), 1980, Apr-12, Volume: 1, Issue:8172

    Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di

1980
[Nifedipine in the treatment of hypertrophic non-obstructive cardiomyopathy].
    Schweizerische medizinische Wochenschrift, 1982, Sep-18, Volume: 112, Issue:38

    Topics: Adult; Cardiac Catheterization; Cardiomegaly; Cardiomyopathy, Hypertrophic; Echocardiography; Female

1982
Nifedipine in the treatment of primary pulmonary hypertension.
    American heart journal, 1983, Volume: 105, Issue:4

    Topics: Adult; Cardiomegaly; Electrocardiography; Female; Humans; Hypertension, Pulmonary; Nifedipine; Physi

1983
Cardiac rhythm in hypertension assessed through 24 hour ambulatory electrocardiographic monitoring. Effects of load manipulation with atenolol, verapamil, and nifedipine.
    British heart journal, 1983, Volume: 50, Issue:2

    Topics: Adult; Atenolol; Cardiomegaly; Echocardiography; Electrocardiography; Female; Heart Conduction Syste

1983
Hypoxia-induced cardiac hypertrophy in rabbits treated with verapamil and nifedipine.
    British journal of pharmacology, 1983, Volume: 80, Issue:2

    Topics: Animals; Cardiomegaly; Eating; Hypoxia; Nifedipine; Organ Size; Rabbits; Verapamil

1983
Assessment of left ventricular performance in patients with variable states of hypertrophy secondary to essential hypertension using a new load-independent index, E' max/V 100.
    Hiroshima journal of medical sciences, 1983, Volume: 32, Issue:4

    Topics: Adult; Aged; Cardiomegaly; Female; Heart; Hemodynamics; Humans; Hypertension; Isosorbide Dinitrate;

1983
[Echocardiographic and arterial pressure changes after acute and prolonged (3 months) administration of nifedipine].
    Medicina clinica, 1984, Jun-23, Volume: 83, Issue:4

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Edema; Heart; Humans; Hypertension; Leg

1984
Left ventricular unloading with calcium antagonists.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:9

    Topics: Cardiac Output; Cardiomegaly; Drug Evaluation; Hemodynamics; Humans; Hypertension; Myocardial Contra

1984
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
    Journal of hypertension, 1984, Volume: 2, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhy

1984
[Effects of nifedipine on left ventricular systolic and diastolic functions in left ventricular hypertrophy].
    Kaku igaku. The Japanese journal of nuclear medicine, 1984, Volume: 21, Issue:10

    Topics: Adult; Calcium Channel Blockers; Cardiomegaly; Diastole; Female; Heart; Humans; Male; Middle Aged; M

1984
Reversal of left ventricular hypertrophy and improvement of cardiac function in man by nifedipine.
    European heart journal, 1984, Volume: 5 Suppl F

    Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiomegaly; Cardiomyopathy, Dilated; Cardiomyopathy,

1984
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
    Paroi arterielle, 1980, Volume: 6, Issue:4

    Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Re

1980
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
    The Journal of toxicological sciences, 1993, Volume: 18 Suppl 3

    Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegal

1993
Shaker-related potassium channel, Kv1.4, mRNA regulation in cultured rat heart myocytes and differential expression of Kv1.4 and Kv1.5 genes in myocardial development and hypertrophy.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1993
Regulation of membrane-mediated chronic muscle degeneration in dystrophic hamsters by calcium-channel blockers: diltiazem, nifedipine and verapamil.
    Journal of the neurological sciences, 1993, Volume: 115, Issue:1

    Topics: Animals; Body Weight; Calcium; Calcium Channel Blockers; Cardiomegaly; Creatine Kinase; Cricetinae;

1993
Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 1996, Volume: 14, Issue:11

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Blood Pressure

1996
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
    Science (New York, N.Y.), 1997, May-02, Volume: 276, Issue:5313

    Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Chan

1997
Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
    Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Collagen; Hear

1998
Effects of taurine on signal transduction steps induced during hypertrophy of rat heart myocytes.
    Advances in experimental medicine and biology, 1998, Volume: 442

    Topics: Angiotensin II; Animals; Calcium; Cardiomegaly; Cells, Cultured; Heart; Myocardium; Nifedipine; Ouab

1998
Nifedipine does not impede clenbuterol-stimulated muscle hypertrophy.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:3

    Topics: Adrenergic beta-Agonists; Animals; Blood Pressure; Body Weight; Calcium; Calcium Channels; Calcium C

1999
Apoptosis during regression of cardiac hypertrophy in spontaneously hypertensive rats. Temporal regulation and spatial heterogeneity.
    Hypertension (Dallas, Tex. : 1979), 1999, Volume: 34, Issue:2

    Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibit

1999
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.
    Pharmacology & toxicology, 2000, Volume: 86, Issue:1

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv

2000
Possible involvement of endothelin-1 in cardioprotective effects of benidipine.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2000, Volume: 23, Issue:5

    Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Dihydropyridines

2000
Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:1

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Calcineurin Inhibitors; Calcium Channel Blockers

2002
Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats.
    The Canadian journal of cardiology, 2002, Volume: 18, Issue:6

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Disease Mo

2002
Effects of nifedipine-GITS on left ventricular mass and left ventricular filling.
    Journal of cardiovascular pharmacology, 1992, Volume: 19 Suppl 2

    Topics: Atrial Natriuretic Factor; Cardiomegaly; Chlorthalidone; Delayed-Action Preparations; Drug Therapy,

1992
Nifedipine in divided doses does not reverse left ventricular hypertrophy in spontaneously hypertensive rats.
    Japanese circulation journal, 1992, Volume: 56, Issue:3

    Topics: Adrenergic Fibers; Animals; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Drug Administ

1992
Differential effects of nifedipine on plasma atrial natriuretic peptide in normal subjects and hypertensive patients.
    Angiology, 1992, Volume: 43, Issue:1

    Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Electrocardiography; Female; H

1992
Normal responsiveness to external Ca and to Ca-channel modifying agents in hypertrophied rat heart.
    The American journal of physiology, 1990, Volume: 258, Issue:6 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1990
Effects of long-term blood pressure control on left and right ventricular structure and function in hypertensive patients.
    Journal of cardiovascular pharmacology, 1991, Volume: 17 Suppl 2

    Topics: Blood Pressure; Captopril; Cardiomegaly; Echocardiography; Echocardiography, Doppler; Female; Heart

1991
Hypertrophy of isolated adult feline heart cells following beta-adrenergic-induced beating.
    The American journal of physiology, 1991, Volume: 261, Issue:3 Pt 1

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cardiomegaly; Cats; Cells, Cultured; Colforsin; Cultu

1991
Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy.
    Journal of cardiovascular pharmacology, 1991, Volume: 18 Suppl 10

    Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cardiomegaly; Energy Metabolism; Hyperten

1991
Vascular injury: mechanisms and manifestations.
    The American journal of medicine, 1991, Apr-25, Volume: 90, Issue:4B

    Topics: Amlodipine; Animals; Aorta, Thoracic; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cardiomeg

1991
[Left ventricular hypertrophy as an indication for the prescribing of calcium antagonists in patients with ischemic heart disease].
    Vrachebnoe delo, 1991, Issue:7

    Topics: Adult; Calcium Channel Blockers; Cardiomegaly; Coronary Disease; Drug Evaluation; Hemodynamics; Huma

1991
Vascular and myocardial effects of amlodipine: an overview.
    Postgraduate medical journal, 1991, Volume: 67 Suppl 5

    Topics: Amlodipine; Animals; Arteriosclerosis; Binding Sites; Calcium Channel Blockers; Cardiomegaly; Cerebr

1991
[Transient subendocardial ischemia in abolition of hypertensive crises with nifedipine].
    Kardiologiia, 1991, Volume: 31, Issue:11

    Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Coronary Disease; Echocardiography; Electrocardiography;

1991
[The effect of lowered pressure on the diastolic ventricular function after antihypertensive treatment].
    Zhonghua xin xue guan bing za zhi, 1991, Volume: 19, Issue:6

    Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Cardiomegaly; Diastole; Female;

1991
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
    The American journal of cardiology, 1990, Apr-03, Volume: 65, Issue:14

    Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary

1990
Effects of nifedipine on transmitral Doppler blood flow velocity profile in patients with concentric left ventricular hypertrophy.
    American heart journal, 1990, Volume: 119, Issue:5

    Topics: Adult; Blood Flow Velocity; Blood Pressure; Cardiomegaly; Diastole; Echocardiography; Echocardiograp

1990
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
    Cor et vasa, 1990, Volume: 32, Issue:1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therap

1990
[Action of sublingual nifedipine on left ventricular filling in hypertensive crisis].
    Archives des maladies du coeur et des vaisseaux, 1990, Volume: 83, Issue:8

    Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Blood Pressure; Cardiomegaly; Echocardio

1990
Regression of cardiac hypertrophy after therapy in animal hypertension.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 2

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Hypertension; Nifedipine; Rats; Rats

1985
Alterations in the plasma membrane properties of the myocardium of spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1986, Volume: 8, Issue:7

    Topics: Adenosine Triphosphatases; Animals; Cardiomegaly; Cell Membrane; Ion Channels; Male; Myocardium; Nif

1986
The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload.
    Journal of cardiovascular pharmacology, 1988, Volume: 12 Suppl 7

    Topics: Aging; Amlodipine; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Coronar

1988
Regression of cardiac hypertrophy: experimental and clinical results.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 6

    Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats,

1987
Left ventricular function and collagen content after regression of hypertensive hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 1989, Volume: 13, Issue:1

    Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Hypertension; Nifedipine; Rats; Rats, Inbred

1989
A case of atrial septal defect combined with hypertension and left ventricular hypertrophy. Left ventricular failure induced by balloon occlusion and the effect of nifedipine.
    Japanese heart journal, 1989, Volume: 30, Issue:1

    Topics: Blood Pressure; Cardiac Output, Low; Cardiomegaly; Catheterization; Female; Heart Septal Defects, At

1989
Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats.
    Clinical and experimental hypertension. Part A, Theory and practice, 1989, Volume: 11, Issue:7

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bridged

1989
Impending myocardial infarction in a patient with marked left ventricular hypertrophy and normal coronary arteriogram--a case report.
    Angiology, 1989, Volume: 40, Issue:11

    Topics: Angiocardiography; Angiography; Cardiomegaly; Coronary Angiography; Echocardiography; Electrocardiog

1989
[Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:8

    Topics: Adult; Cardiomegaly; Drug Evaluation; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; M

1989
Regression of left ventricular hypertrophy by acebutolol and nifedipine.
    Cardiovascular drugs and therapy, 1989, Volume: 3 Suppl 1

    Topics: Acebutolol; Blood Pressure; Cardiomegaly; Drug Combinations; Echocardiography; Humans; Hypertension;

1989
Regression of heart muscle hypertrophy after nifedipine therapy: changes in cardiac gene expression.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1985, Volume: 3, Issue:3

    Topics: Animals; Cardiomegaly; Gene Expression; Muscle Proteins; Myocardium; Nifedipine; Rats; Rats, Inbred

1985
Acute effect of nifedipine on blood pressure and left ventricular ejection fraction in severely hypertensive outpatients: predictive effects of acute therapy and prolonged efficacy when added to existing therapy.
    American heart journal, 1986, Volume: 111, Issue:3

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; F

1986
Renal and cardiovascular effects of acute and chronic administration of felodipine to SHR.
    European journal of pharmacology, 1985, Jul-11, Volume: 113, Issue:1

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Felodipine; Furosemide; Heart Rate;

1985
Use of nifedipine as monotherapy in the management of hypertension.
    The American journal of medicine, 1985, Oct-11, Volume: 79, Issue:4A

    Topics: Adult; Blood Pressure; Cardiomegaly; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Ni

1985
[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects].
    Zeitschrift fur Kardiologie, 1985, Volume: 74 Suppl 7

    Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Cardiomyopathy, Hypertrophic; Clonidine; Coronary Circ

1985
[Stress pulsed Doppler echocardiography in the evaluation of diastolic left ventricular function].
    Journal of cardiography, 1985, Volume: 15, Issue:2

    Topics: Cardiomegaly; Cardiomyopathy, Hypertrophic; Coronary Disease; Diastole; Echocardiography; Heart Vent

1985
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
    The American review of respiratory disease, 1986, Volume: 133, Issue:3

    Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle

1986
Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats.
    Hypertension (Dallas, Tex. : 1979), 1987, Volume: 10, Issue:3

    Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Hypertension; Male; Nifedipine; Ni

1987
Cardiac hypertrophy in hypertension. Repolarization abnormalities elicited by rapid lowering of pressure.
    Hypertension (Dallas, Tex. : 1979), 1988, Volume: 11, Issue:1

    Topics: Adult; Blood Pressure; Cardiomegaly; Electrocardiography; Female; Heart Rate; Humans; Hypertension;

1988
Long-term effect of antihypertensive therapy on left ventricular hypertrophy.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1987, Volume: 5, Issue:5

    Topics: Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Echocardiography;

1987
Regression of left ventricular hypertrophy during combined atenolol and nifedipine treatment.
    Drugs, 1988, Volume: 35 Suppl 4

    Topics: Adult; Atenolol; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; Echocardiography; Exercise

1988
Electrocardiographic alterations suggestive of myocardial injury elicited by rapid pressure lowering in hypertension.
    European heart journal, 1988, Volume: 9, Issue:8

    Topics: Adult; Blood Pressure; Cardiomegaly; Coronary Circulation; Electrocardiography; Ferricyanides; Heart

1988
Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function.
    Archives of internal medicine, 1985, Volume: 145, Issue:2

    Topics: Aged; Cardiomegaly; Electrocardiography; Female; Heart Failure; Heart Ventricles; Humans; Hypertensi

1985
Cardiac hypertrophy and arterial distensibility in essential hypertension.
    American heart journal, 1985, Volume: 109, Issue:6

    Topics: Adult; Aged; Arteries; Blood Flow Velocity; Cardiomegaly; Humans; Hypertension; Middle Aged; Nifedip

1985