Page last updated: 2024-11-01

nifedipine and Cancer of Prostate

nifedipine has been researched along with Cancer of Prostate in 10 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"To compare the efficacy of periprostatic nerve block (PNB) alone vs PNB combined with the local administration of a 1."2.74Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study. ( Cantiello, F; Di Meo, S; Fusco, F; Iannuzzo, M; Imbimbo, C; Imperatore, V; Mirone, V; Scibelli, G, 2009)
"Fourteen human cancer cell lines with and without DNA MMR derived from carcinomas of the colon, bladder, ovary and prostate were treated with CAI, vehicle or control drugs (nifedipine and 5-flurouracil)."1.35Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency. ( Friedlander, ML; Kohn, EC; Qu, XJ; Yang, JL; Yu, Y, 2008)
"To better understand NT signaling in prostate cancer PC3 cells, blockers of voltage-gated and store-operated Ca2+ channels (VGCC and SOCC) were tested for effects on NT-binding and signaling."1.32Ca2+ channel blockers enhance neurotensin (NT) binding and inhibit NT-induced inositol phosphate formation in prostate cancer PC3 cells. ( Carraway, RE; Cochrane, DE; Gui, X, 2003)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (30.00)18.2507
2000's6 (60.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
De Petrocellis, L1
Arroyo, FJ1
Orlando, P1
Schiano Moriello, A1
Vitale, RM1
Amodeo, P1
Sánchez, A1
Roncero, C1
Bianchini, G1
Martín, MA1
López-Alvarado, P1
Menéndez, JC1
Cantiello, F1
Imperatore, V1
Iannuzzo, M1
Scibelli, G1
Di Meo, S1
Fusco, F1
Imbimbo, C1
Mirone, V1
Carraway, RE1
Gui, X1
Cochrane, DE1
Rekasi, Z1
Czompoly, T1
Schally, AV1
Boldizsar, F1
Varga, JL1
Zarandi, M1
Berki, T1
Horvath, RA1
Nemeth, P1
Yang, JL1
Qu, XJ1
Yu, Y1
Kohn, EC1
Friedlander, ML1
Sugimoto, K1
Simard, J1
Haagensen, DE1
Labrie, F1
Nickerson, T1
Miyake, H1
Gleave, ME1
Pollak, M1
Ando, Y1
Tateishi, T1
Sekido, Y1
Yamamoto, T1
Satoh, T1
Hasegawa, Y1
Kobayashi, S1
Katsumata, Y1
Shimokata, K1
Saito, H1
Chien, J1
Shah, GV1
Jan, CR1
Jiann, BP1
Lu, YC1
Chang, HT1
Su, W1
Chen, WC1
Yu, CC1
Huang, JK1

Trials

1 trial available for nifedipine and Cancer of Prostate

ArticleYear
Periprostatic nerve block (PNB) alone vs PNB combined with an anaesthetic-myorelaxant agent cream for prostate biopsy: a prospective, randomized double-arm study.
    BJU international, 2009, Volume: 103, Issue:9

    Topics: Aged; Anesthetics, Local; Biopsy, Needle; Drug Therapy, Combination; Epidemiologic Methods; Humans;

2009

Other Studies

9 other studies available for nifedipine and Cancer of Prostate

ArticleYear
Tetrahydroisoquinoline-Derived Urea and 2,5-Diketopiperazine Derivatives as Selective Antagonists of the Transient Receptor Potential Melastatin 8 (TRPM8) Channel Receptor and Antiprostate Cancer Agents.
    Journal of medicinal chemistry, 2016, 06-23, Volume: 59, Issue:12

    Topics: Animals; Antineoplastic Agents; Calcium; Cell Proliferation; Diketopiperazines; Dose-Response Relati

2016
Ca2+ channel blockers enhance neurotensin (NT) binding and inhibit NT-induced inositol phosphate formation in prostate cancer PC3 cells.
    The Journal of pharmacology and experimental therapeutics, 2003, Volume: 307, Issue:2

    Topics: Binding Sites; Calcium; Calcium Channel Blockers; Endocytosis; Enzyme Inhibitors; Epidermal Growth F

2003
Antagonist of growth hormone-releasing hormone induces apoptosis in LNCaP human prostate cancer cells through a Ca2+-dependent pathway.
    Proceedings of the National Academy of Sciences of the United States of America, 2005, Mar-01, Volume: 102, Issue:9

    Topics: Apoptosis; Calcium; Cell Line, Tumor; Edetic Acid; Flow Cytometry; Growth Hormone-Releasing Hormone;

2005
Selective sensitivity to carboxyamidotriazole by human tumor cell lines with DNA mismatch repair deficiency.
    International journal of cancer, 2008, Jul-15, Volume: 123, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Calcium Channel Blockers; Cell Cycle; Cell Line, Tumor; Chromosome

2008
Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells.
    The Journal of steroid biochemistry and molecular biology, 1994, Volume: 51, Issue:3-4

    Topics: Apolipoproteins; Apolipoproteins D; Cell Division; Dihydrotestosterone; Humans; Male; Nifedipine; Pr

1994
Castration-induced apoptosis of androgen-dependent shionogi carcinoma is associated with increased expression of genes encoding insulin-like growth factor-binding proteins.
    Cancer research, 1999, Jul-15, Volume: 59, Issue:14

    Topics: Amlodipine; Animals; Apoptosis; Calcium Channel Blockers; Calcium Signaling; Carcinoma; Gene Express

1999
Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.
    Journal of the National Cancer Institute, 1999, Sep-15, Volume: 91, Issue:18

    Topics: Asian People; Calcium Channel Blockers; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzy

1999
Role of stimulatory guanine nucleotide binding protein (GSalpha) in proliferation of PC-3M prostate cancer cells.
    International journal of cancer, 2001, Jan-01, Volume: 91, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Blotting, Western; Calcitonin; Calcium Ch

2001
Effect of the organotin compound triethyltin on Ca2+ handling in human prostate cancer cells.
    Life sciences, 2002, Feb-01, Volume: 70, Issue:11

    Topics: Calcium; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Antagonism; Fura-2; Hu

2002