Page last updated: 2024-11-01

nifedipine and Cancer of Pituitary

nifedipine has been researched along with Cancer of Pituitary in 32 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"A patient with a rare combination of prolactinoma and aldosterone producing adrenal adenoma (APA) was reported in relation to studies concerning dopaminergic regulation of PRL and aldosterone secretion."5.28A patient with a prolactinoma associated with an aldosterone producing adrenal adenoma: differences in dopaminergic regulation of PRL and aldosterone secretion. ( Demura, H; Demura, R; Isawa, M; Naruse, K; Naruse, M; Onoda, N; Yamakado, M, 1992)
"Mastoparan has been reported to induce a wide variety of cellular actions by activating GTP-binding proteins (G proteins) in various cells."1.30Mastoparan-stimulated prolactin secretion in rat pituitary GH3 cells involves activation of Gq/11 proteins. ( Ito, H; Kawashima, S; Uchino, K; Yajima, Y, 1997)
"A patient with a rare combination of prolactinoma and aldosterone producing adrenal adenoma (APA) was reported in relation to studies concerning dopaminergic regulation of PRL and aldosterone secretion."1.28A patient with a prolactinoma associated with an aldosterone producing adrenal adenoma: differences in dopaminergic regulation of PRL and aldosterone secretion. ( Demura, H; Demura, R; Isawa, M; Naruse, K; Naruse, M; Onoda, N; Yamakado, M, 1992)
"Maitotoxin has been reported to activate calcium channels and stimulate calcium-dependent functions in several tissues, but a thorough investigation of 45Ca2+ fluxes is lacking."1.27The effects of maitotoxin on 45Ca2+ flux and hormone release in GH3 rat pituitary cells. ( Cronin, MJ; Judd, AM; Koike, K; Login, IS; MacLeod, RM; Schettini, G; Yasumoto, T, 1985)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199013 (40.63)18.7374
1990's15 (46.88)18.2507
2000's4 (12.50)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bulayeva, NN1
Wozniak, AL1
Lash, LL1
Watson, CS1
Dominguez, B1
Felix, R1
Monjaraz, E1
Enyeart, JJ3
Hinkle, PM3
Albert, PR1
Tashjian, AH1
De Vries, GW1
McLaughlin, A1
Wenzel, MB1
Perez, J1
Harcourt, D1
Lee, G1
Garst, M1
Wheeler, LA1
Levitan, ES1
Gealy, R1
Trimmer, JS1
Takimoto, K1
Gross, RA1
Huggenvik, J1
Massa, E1
Allen, RG1
Uhler, MD1
Clark, TP1
Kemppainen, RJ1
Inukai, T1
Wang, X1
Greer, SE4
Greer, MA4
Yajima, Y1
Uchino, K1
Ito, H1
Kawashima, S1
Yin, J2
Deng, J2
Shi, Y2
Shu, C1
Kwiecien, R1
Robert, C1
Cannon, R1
Vigues, S1
Arnoux, A1
Kordon, C1
Hammond, C1
Motoyoshi, S1
Shirotani, T1
Araki, E1
Sakai, K1
Kaneko, K1
Motoshima, H1
Yoshizato, K1
Shirakami, A1
Kishikawa, H1
Shichiri, M1
Cely, CM1
Contreras, G1
Lo, YK1
Wu, SN1
Lee, CT1
Li, HF1
Chiang, HT1
Demura, R1
Naruse, M1
Isawa, M1
Onoda, N1
Naruse, K1
Yamakado, M1
Demura, H1
Sato, N3
Wang, XB3
McAdams, S3
Sei, CA1
Glembotski, CC1
Oshima, T1
Cronin, MJ2
Anderson, JM1
Rogol, AD1
Koritnik, DR1
Thorner, MO1
Evans, WS1
Heisler, S2
Aizawa, T2
Gershengorn, MC2
Thaw, CN1
Geras-Raaka, E1
Login, IS1
Judd, AM1
Koike, K1
Schettini, G1
Yasumoto, T1
MacLeod, RM1
Shangold, GA1
Kongsamut, S1
Miller, RJ1
Luini, A1
Corda, D1
Axelrod, J1
Wolfe, SE1
Brostrom, CO1
Brostrom, MA1
Thaw, C1

Other Studies

32 other studies available for nifedipine and Cancer of Pituitary

ArticleYear
Mechanisms of membrane estrogen receptor-alpha-mediated rapid stimulation of Ca2+ levels and prolactin release in a pituitary cell line.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:2

    Topics: Animals; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Membrane; Dose-Response Relationship, Dr

2005
Ghrelin and GHRP-6 enhance electrical and secretory activity in GC somatotropes.
    Biochemical and biophysical research communications, 2007, Jun-22, Volume: 358, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

2007
The calcium agonist Bay K 8644 stimulates secretion from a pituitary cell line.
    Biochemical and biophysical research communications, 1984, Aug-16, Volume: 122, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1984
Relationship of thyrotropin-releasing hormone-induced spike and plateau phases in cytosolic free Ca2+ concentrations to hormone secretion. Selective blockade using ionomycin and nifedipine.
    The Journal of biological chemistry, 1984, Dec-25, Volume: 259, Issue:24

    Topics: Animals; Calcium; Cell Line; Cytosol; Ethers; Growth Hormone; Ionomycin; Kinetics; Nifedipine; Pitui

1984
The antiinflammatory activity of topically applied novel calcium-channel antagonists.
    Inflammation, 1995, Volume: 19, Issue:2

    Topics: Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Calci

1995
Membrane depolarization inhibits Kv1.5 voltage-gated K+ channel gene transcription and protein expression in pituitary cells.
    The Journal of biological chemistry, 1995, Mar-17, Volume: 270, Issue:11

    Topics: Amiloride; Animals; Calcium; Clone Cells; Down-Regulation; Gene Expression; Kv1.5 Potassium Channel;

1995
Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells.
    Molecular endocrinology (Baltimore, Md.), 1994, Volume: 8, Issue:8

    Topics: Adrenocorticotropic Hormone; Allosteric Site; Animals; beta-Endorphin; Binding Sites; Calcium; Calci

1994
Glucocorticoid negative feedback in sheep corticotrophs: a comparison with AtT-20 corticotroph tumor cells.
    The American journal of physiology, 1994, Volume: 267, Issue:2 Pt 2

    Topics: Adrenocorticotropic Hormone; Animals; Dexamethasone; Feedback; Glucocorticoids; Male; Nifedipine; Os

1994
Adenosine 3',5'-cyclic monophosphate-mediated prolactin secretion in GH4C1 cells involves Ca2+ influx through L-type Ca2+ channels.
    Cell calcium, 1993, Volume: 14, Issue:3

    Topics: Adenylyl Cyclases; Animals; Bucladesine; Calcium; Calcium Channels; Colforsin; Cyclic AMP; Dose-Resp

1993
Mastoparan-stimulated prolactin secretion in rat pituitary GH3 cells involves activation of Gq/11 proteins.
    Endocrinology, 1997, Volume: 138, Issue:5

    Topics: Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Exocytosis; GTP-Binding Proteins; Inositol P

1997
[The role of Ca2+ in the pathogenesis of human pituitary GH-secreting adenomas].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 1996, Volume: 18, Issue:1

    Topics: Adenoma; Biological Transport, Active; Calcimycin; Calcium; Calcium Channel Blockers; Growth Hormone

1996
The role of calcium ion in the pathogenesis of human pituitary GH-secreting adenomas.
    Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1996, Volume: 11, Issue:4

    Topics: Adenoma; Biological Transport, Active; Calcium; Calcium Channel Blockers; Growth Hormone; Growth Hor

1996
Endogenous pacemaker activity of rat tumour somatotrophs.
    The Journal of physiology, 1998, May-01, Volume: 508 ( Pt 3)

    Topics: Action Potentials; Animals; Antisense Elements (Genetics); Apamin; Barium; Biological Clocks; Cadmiu

1998
Cellular characterization of pituitary adenoma cell line (AtT20 cell) transfected with insulin, glucose transporter type 2 (GLUT2) and glucokinase genes: insulin secretion in response to physiological concentrations of glucose.
    Diabetologia, 1998, Volume: 41, Issue:12

    Topics: Adenoma; Calcium Channel Blockers; Corticotropin-Releasing Hormone; Diazoxide; Gene Expression; Gluc

1998
Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosis.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2001, Volume: 37, Issue:3

    Topics: Adenoma; Adrenalectomy; Aldosterone; Alkalosis; Antihypertensive Agents; Diagnosis, Differential; Hu

2001
Characterization of action potential waveform-evoked L-type calcium currents in pituitary GH3 cells.
    Pflugers Archiv : European journal of physiology, 2001, Volume: 442, Issue:4

    Topics: Action Potentials; Adenoma; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Da

2001
A patient with a prolactinoma associated with an aldosterone producing adrenal adenoma: differences in dopaminergic regulation of PRL and aldosterone secretion.
    Endocrinologia japonica, 1992, Volume: 39, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Aldosterone; Bromocriptine; Dopamine; Female; Humans; Metoc

1992
Evidence that ethanol induces prolactin secretion in GH4C1 cells by producing cell swelling with resultant calcium influx.
    Endocrinology, 1990, Volume: 127, Issue:6

    Topics: Animals; Calcium; Cell Line; Ethanol; Kinetics; Mannitol; Nifedipine; Osmolar Concentration; Pituita

1990
Calcium dependence of phenylephrine-, endothelin-, and potassium chloride-stimulated atrial natriuretic factor secretion from long term primary neonatal rat atrial cardiocytes.
    The Journal of biological chemistry, 1990, May-05, Volume: 265, Issue:13

    Topics: Adrenocorticotropic Hormone; Animals; Animals, Newborn; Atrial Function; Atrial Natriuretic Factor;

1990
The permeant molecule urea stimulates prolactin secretion in GH4C1 cells by inducing Ca2+ influx through dihydropyridine-sensitive Ca2+ channels.
    Molecular and cellular endocrinology, 1990, May-07, Volume: 70, Issue:3

    Topics: Animals; Calcium; Calcium Channels; Nifedipine; Osmolar Concentration; Pituitary Neoplasms; Prolacti

1990
Medium hyposmolarity stimulates prolactin secretion in GH4C1 cells by inducing an increase in cytosolic free calcium.
    Endocrinology, 1990, Volume: 127, Issue:2

    Topics: Animals; Calcium; Cell Line; Culture Media; Cytosol; Hypotonic Solutions; Kinetics; Nifedipine; Pitu

1990
Calcium channel agonist BAY k8644 enhances anterior pituitary secretion in rat and monkey.
    The American journal of physiology, 1985, Volume: 249, Issue:3 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Stimulation of adrenocorticotropin secretion from AtT-20 cells by the calcium channel activator, BAY-K-8644, and its inhibition by somatostatin and carbachol.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 235, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Interaction of dihydropyridine Ca2+ agonist Bay K 8644 with normal and transformed pituitary cells.
    The American journal of physiology, 1986, Volume: 250, Issue:1 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
BAY-K-8644-stimulated cyclic GMP synthesis in mouse pituitary tumor cells.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 236, Issue:3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1986
Benzodiazepines modulate voltage-sensitive calcium channels in GH3 pituitary cells at sites distinct from thyrotropin-releasing hormone receptors.
    Endocrinology, 1988, Volume: 123, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Benzodiazepinones; Calcium; Cell Line; Chlordiazepoxide; Diazepam; Dil

1988
The effects of maitotoxin on 45Ca2+ flux and hormone release in GH3 rat pituitary cells.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Animals; Calcium; Cell Line; Gallopamil; Growth Hormone; Ion Channels; Manganese; Marine Toxins; Nif

1985
Characterization of voltage-sensitive calcium channels in a clonal pituitary cell line.
    Life sciences, 1985, Jun-10, Volume: 36, Issue:23

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e

1985
Secretagogues elevate cytosolic calcium by stimulating cyclic AMP formation in a corticotropin secreting cell line.
    Regulatory peptides. Supplement, 1985, Volume: 4

    Topics: Adrenocorticotropic Hormone; Animals; Calcium; Cell Line; Cyclic AMP; Cytosol; Mice; Nifedipine; Pit

1985
Mechanisms of action of inhibitors of prolactin secretion in GH3 pituitary cells. I. Ca2+-dependent inhibition of amino acid incorporation.
    Molecular pharmacology, 1986, Volume: 29, Issue:4

    Topics: Acetylcholine; Amino Acids; Animals; Bromocriptine; Calcium; Carbachol; Cell Line; Chlorpromazine; I

1986
Thyrotropin-releasing hormone (TRH) stimulates biphasic elevation of cytoplasmic free calcium in GH3 cells. Further evidence that TRH mobilizes cellular and extracellular Ca2+.
    Endocrinology, 1985, Volume: 116, Issue:2

    Topics: Aminoquinolines; Animals; Calcium; Cell Line; Cytoplasm; Extracellular Space; Fluorescent Dyes; Nife

1985
Dihydropyridine Ca2+ antagonists: potent inhibitors of secretion from normal and transformed pituitary cells.
    The American journal of physiology, 1985, Volume: 248, Issue:5 Pt 1

    Topics: Animals; Calcium Channel Blockers; Cell Line; Growth Hormone; Nicotinic Acids; Nifedipine; Nimodipin

1985