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nifedipine and Calcinosis

nifedipine has been researched along with Calcinosis in 17 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Calcinosis: Pathologic deposition of calcium salts in tissues.

Research Excerpts

ExcerptRelevanceReference
"Nifedipine GITS was not effective in slowing down the progression of calcium in advanced atherosclerotic plaques in patients with stable angina pectoris."7.74Tracking coronary calcification and atherosclerotic lesions in patients with stable angina pectoris undergoing nifedipine therapy. ( de Brouwer, S; Kirwan, BA; Motro, M; Poole-Wilson, PA; Shemesh, J, 2007)
"The effects of nifedipine on the survival rate and the cardiovascular calcinosis were investigated in dietary magnesium (Mg)-deficient mice."7.68Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice. ( Ishiguro, S; Nishio, A; Sakaguchi, H; Sakaguchi, R, 1992)
"Protective effects of benidipine hydrochloride (KW-3049) against arterial calcinosis and its possible mechanisms of action have been investigated."7.68Protective effects of benidipine hydrochloride (KW-3049), a calcium antagonist, against experimental arterial calcinosis and endothelial dysfunction in rats. ( Higo, K; Karasawa, A; Kubo, K, 1992)
"Ten patients with pulmonary hypertension associated with diffuse systemic sclerosis (1 patient), the CREST syndrome (calcinosis cutis, Reynaud's phenomenon, esophageal dysmotility, sclerodactyl, telangiectasia) (6 patients) and mixed connective tissue disease (3 patients) were studied to assess the effect of oral nifedipine on pulmonary and systemic hemodynamics."7.68Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. ( Alpert, MA; Lambert, CR; Mukerji, B; Mukerji, V; Panayiotou, H; Pressly, TA; Sharp, GC, 1991)
" The study was designed as a side arm of INSIGHT (International Nifedipine Study: Intervention as Goal for Hypertension Therapy), aimed to show the efficacy of nifedipine once daily versus co-amilozide (hydrochlorothiazide 25 mg, amiloride 2."5.09Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics. ( Motro, M; Shemesh, J, 2001)
"6 years, 54% men), a subgroup of 544 participants in the calcification side arm of the INSIGHT (International Nifedipine Study Intervention as Goal for Hypertension Therapy)."3.79Progression of coronary artery calcification is associated with long-term cardiovascular events in hypertensive adults. ( Apter, S; Grossman, C; Grossman, E; Morag-Koren, N; Motro, M; Shemesh, J, 2013)
"Nifedipine GITS was not effective in slowing down the progression of calcium in advanced atherosclerotic plaques in patients with stable angina pectoris."3.74Tracking coronary calcification and atherosclerotic lesions in patients with stable angina pectoris undergoing nifedipine therapy. ( de Brouwer, S; Kirwan, BA; Motro, M; Poole-Wilson, PA; Shemesh, J, 2007)
"The effects of nifedipine on the survival rate and the cardiovascular calcinosis were investigated in dietary magnesium (Mg)-deficient mice."3.68Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice. ( Ishiguro, S; Nishio, A; Sakaguchi, H; Sakaguchi, R, 1992)
"Protective effects of benidipine hydrochloride (KW-3049) against arterial calcinosis and its possible mechanisms of action have been investigated."3.68Protective effects of benidipine hydrochloride (KW-3049), a calcium antagonist, against experimental arterial calcinosis and endothelial dysfunction in rats. ( Higo, K; Karasawa, A; Kubo, K, 1992)
"Ten patients with pulmonary hypertension associated with diffuse systemic sclerosis (1 patient), the CREST syndrome (calcinosis cutis, Reynaud's phenomenon, esophageal dysmotility, sclerodactyl, telangiectasia) (6 patients) and mixed connective tissue disease (3 patients) were studied to assess the effect of oral nifedipine on pulmonary and systemic hemodynamics."3.68Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease. ( Alpert, MA; Lambert, CR; Mukerji, B; Mukerji, V; Panayiotou, H; Pressly, TA; Sharp, GC, 1991)
"We examined the progression of coronary atherosclerosis, as measured by dual-section spiral computed tomography, using the total coronary artery calcium score as a quantitative measure of the burden of atherosclerosis."2.71Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation. ( Bursztyn, M; Grossman, E; Motro, M; Shemesh, J, 2003)
"Does nifedipine treatment slow down the progression of coronary calcification in diabetic patients? If the answer is yes, is this beneficial effect of nifedipine superior to that of other DHPs with equihypotensive properties? Does nifedipine treatment decrease expression levels of AGEs and RAGE in diabetic atherosclerosis? Is the unique effect of nifedipine on vascular calcification correlated with its AGE or RAGE-suppressing properties? These prospective studies will provide further valuable information whether nifedipine could prevent vascular calcification in diabetic atherosclerosis by blockade the AGE-RAGE signaling in vascular wall cells."1.34Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker. ( Matsui, T; Nakamura, K; Yamagishi, S, 2007)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19905 (29.41)18.7374
1990's5 (29.41)18.2507
2000's6 (35.29)29.6817
2010's1 (5.88)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shemesh, J6
Motro, M6
Grossman, C1
Morag-Koren, N1
Apter, S1
Grossman, E2
Bursztyn, M1
Kirwan, BA1
de Brouwer, S1
Poole-Wilson, PA1
Yamagishi, S1
Matsui, T1
Nakamura, K1
Eisen, A1
Tenenbaum, A1
Koren-Morag, N1
Tanne, D1
Golan, A1
Fisman, EZ1
Schwammenthal, E1
Adler, Y1
Litovchik, I1
Krakover, R1
Blatt, A1
Vered, Z1
Cacciapuoti, F1
Perrone, N1
Diaspro, R1
Galzerano, D1
Gentile, S1
Lapiello, B1
Schäfer, HJ1
Riesner, K1
Sakaguchi, H1
Sakaguchi, R1
Ishiguro, S1
Nishio, A1
Higo, K1
Karasawa, A1
Kubo, K1
Alpert, MA2
Pressly, TA2
Mukerji, V2
Lambert, CR1
Mukerji, B1
Panayiotou, H1
Sharp, GC2
Winkler, A1
Jackson, RW1
Benge, JM1
Krog, M1
Ejerblad, S1
Johansson, H1
Wilander, E1
Orimo, H1
Terashita, K1
Nakamura, T1
Ohshima, J1
Henry, PD1

Reviews

1 review available for nifedipine and Calcinosis

ArticleYear
Atherosclerosis, calcium, and calcium antagonists.
    Circulation, 1985, Volume: 72, Issue:3

    Topics: Animals; Aorta; Arteries; Arteriosclerosis; Calcinosis; Calcium; Calcium Channel Blockers; Cell Surv

1985

Trials

4 trials available for nifedipine and Calcinosis

ArticleYear
Accelerated coronary artery calcification in mildly reduced renal function of high-risk hypertensives: a 3-year prospective observation.
    Journal of hypertension, 2003, Volume: 21, Issue:10

    Topics: Aged; Benzothiadiazines; Calcinosis; Calcium Channel Blockers; Coronary Artery Disease; Diuretics; F

2003
Coronary and aortic calcifications inter-relationship in stable angina pectoris: A Coronary Disease Trial Investigating Outcome with Nifedipine GITS (ACTION)--Israeli spiral computed tomography substudy.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aorta, Thoracic; Aortic Diseases; Calcinosis; Coron

2007
Slowing of mitral valve annular calcium in systemic hypertension by nifedipine and comparisons with enalapril and atenolol.
    The American journal of cardiology, 1993, Nov-01, Volume: 72, Issue:14

    Topics: Adult; Atenolol; Calcinosis; Echocardiography, Doppler; Enalapril; Female; Heart Valve Diseases; Hum

1993
Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:6

    Topics: Aged; Amiloride; Calcinosis; Calcium Channel Blockers; Cardiomyopathies; Coronary Artery Disease; Di

2001

Other Studies

12 other studies available for nifedipine and Calcinosis

ArticleYear
Progression of coronary artery calcification is associated with long-term cardiovascular events in hypertensive adults.
    Journal of hypertension, 2013, Volume: 31, Issue:9

    Topics: Adult; Aged; Calcinosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Vessels; Disease

2013
Tracking coronary calcification and atherosclerotic lesions in patients with stable angina pectoris undergoing nifedipine therapy.
    Cardiology, 2007, Volume: 107, Issue:3

    Topics: Aged; Angina Pectoris; Atherosclerosis; Calcinosis; Calcium Channel Blockers; Coronary Vessels; Fema

2007
Prevention of diabetic vascular calcification by nifedipine, a dihydropyridine-based calcium channel blocker.
    Medical hypotheses, 2007, Volume: 68, Issue:5

    Topics: Calcinosis; Calcium Channel Blockers; Diabetes Mellitus; Dihydropyridines; Humans; Models, Biologica

2007
Coronary and aortic calcification: is the relationship important?
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Aorta, Thoracic; Aortic Diseases; Calcinosis; Coron

2007
Prevalence of coronary calcification in relation to age, gender and risk factor profile in the insight population.
    British journal of clinical practice. Supplement, 1997, Volume: 88

    Topics: Calcinosis; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Diabetes Complications

1997
[Calcium kinetics of myocardium in experimental hypercalcemia and isoproterenol lesions--ultrastructural and roentgen microanalytical findings].
    Verhandlungen der Deutschen Gesellschaft fur Pathologie, 1978, Volume: 62

    Topics: Animals; Calcinosis; Calcium; Dihydrotachysterol; Etidronic Acid; Heart; Hypercalcemia; Isoprotereno

1978
Beneficial effects of a calcium antagonist, nifedipine, on death and cardiovascular calcinosis induced by dietary magnesium deficiency in adult mice.
    Magnesium research, 1992, Volume: 5, Issue:2

    Topics: Animals; Aortic Diseases; Calcinosis; Calcium; Cardiomyopathies; Diet; Magnesium; Magnesium Deficien

1992
Protective effects of benidipine hydrochloride (KW-3049), a calcium antagonist, against experimental arterial calcinosis and endothelial dysfunction in rats.
    Journal of pharmacobio-dynamics, 1992, Volume: 15, Issue:3

    Topics: Acetylcholine; Animals; Aorta; Arteries; Calcinosis; Calcium; Calcium Channel Blockers; Endothelium,

1992
Acute and long-term effects of nifedipine on pulmonary and systemic hemodynamics in patients with pulmonary hypertension associated with diffuse systemic sclerosis, the CREST syndrome and mixed connective tissue disease.
    The American journal of cardiology, 1991, Dec-15, Volume: 68, Issue:17

    Topics: Adult; Blood Pressure; Calcinosis; Cardiac Catheterization; Cardiac Output; Dyspnea; Esophageal Moti

1991
Value and limitations of calcium channel blockade in the treatment of pulmonary hypertension associated with CREST--case reports.
    Angiology, 1988, Volume: 39, Issue:4

    Topics: Adult; Calcinosis; Diltiazem; Esophageal Diseases; Female; Humans; Hypertension, Pulmonary; Male; Mi

1988
Tissue calcification and alkaline phosphatase activity in uraemic rats.
    Scandinavian journal of urology and nephrology, 1988, Volume: 22, Issue:1

    Topics: Alkaline Phosphatase; Animals; Aortic Diseases; Calcinosis; Calcitriol; Cardiomyopathies; Creatinine

1988
Ca and atherosclerosis.
    Journal of nutritional science and vitaminology, 1985, Volume: 31 Suppl

    Topics: Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Bone Diseases; Calcinosis; Calcium; Calcium

1985