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nifedipine and Bronchopulmonary Dysplasia

nifedipine has been researched along with Bronchopulmonary Dysplasia in 6 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.

Research Excerpts

ExcerptRelevanceReference
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."9.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"The pharmacokinetics and associated pharmacodynamics of nifedipine were studied in nine children aged 5 to 68 mo with bronchopulmonary dysplasia and pulmonary artery hypertension after a single oral dose of 1."7.68Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension. ( Amidon, GL; Beekman, RH; Johnson, CE; Kostyshak, DA; Nguyen, T; Oh, DM, 1991)
"The acute hemodynamic effects of nifedipine were evaluated and compared to the effects of 95% oxygen in six children with bronchopulmonary dysplasia and pulmonary artery hypertension."7.67Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension. ( Beekman, RH; Brownlee, JR; Rosenthal, A, 1988)
"A two-year-old child dying of pulmonary hypertension and cor pulmonale secondary to bronchopulmonary dysplasia, was demonstrated to have reactive pulmonary hypertension in response to 100% oxygen and isoproterenol infusion."5.06Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia. ( Bingham, WT; Duncan, WJ; Kasian, GF; Mersal, A; Ninan, A; Sankaran, K; Tyrrell, MJ, 1988)
"The pharmacokinetics and associated pharmacodynamics of nifedipine were studied in nine children aged 5 to 68 mo with bronchopulmonary dysplasia and pulmonary artery hypertension after a single oral dose of 1."3.68Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension. ( Amidon, GL; Beekman, RH; Johnson, CE; Kostyshak, DA; Nguyen, T; Oh, DM, 1991)
"The acute hemodynamic effects of nifedipine were evaluated and compared to the effects of 95% oxygen in six children with bronchopulmonary dysplasia and pulmonary artery hypertension."3.67Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension. ( Beekman, RH; Brownlee, JR; Rosenthal, A, 1988)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19903 (50.00)18.7374
1990's2 (33.33)18.2507
2000's1 (16.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rosati, E1
Butera, G1
Bossone, E1
De Felice, C1
Latini, G1
Johnson, CE1
Beekman, RH2
Kostyshak, DA1
Nguyen, T1
Oh, DM1
Amidon, GL1
Davis, JM1
Sinkin, RA1
Aranda, JV1
Brownlee, JR1
Rosenthal, A1
Kasian, GF1
Ninan, A1
Duncan, WJ1
Bingham, WT1
Mersal, A1
Tyrrell, MJ1
Sankaran, K1
Kochanek, PM1
Zaritsky, A1

Reviews

1 review available for nifedipine and Bronchopulmonary Dysplasia

ArticleYear
Drug therapy for bronchopulmonary dysplasia.
    Pediatric pulmonology, 1990, Volume: 8, Issue:2

    Topics: Bronchodilator Agents; Bronchopulmonary Dysplasia; Diuretics; Humans; Infant, Newborn; Nifedipine

1990

Trials

1 trial available for nifedipine and Bronchopulmonary Dysplasia

ArticleYear
Treatment of pulmonary hypertension with diltiazem in a child with bronchopulmonary dysplasia.
    The Canadian journal of cardiology, 1988, Volume: 4, Issue:4

    Topics: Albuterol; Bronchopulmonary Dysplasia; Child, Preschool; Diltiazem; Humans; Hydralazine; Hypertensio

1988

Other Studies

4 other studies available for nifedipine and Bronchopulmonary Dysplasia

ArticleYear
Inhaled nitric oxide and oral nifedipine in a preterm infant with bronchopulmonary dysplasia and pulmonary hypertension.
    European journal of pediatrics, 2007, Volume: 166, Issue:7

    Topics: Administration, Inhalation; Administration, Oral; Bronchodilator Agents; Bronchopulmonary Dysplasia;

2007
Pharmacokinetics and pharmacodynamics of nifedipine in children with bronchopulmonary dysplasia and pulmonary hypertension.
    Pediatric research, 1991, Volume: 29, Issue:5

    Topics: Administration, Oral; Bronchopulmonary Dysplasia; Child, Preschool; Diuretics; Female; Hemodynamics;

1991
Acute hemodynamic effects of nifedipine in infants with bronchopulmonary dysplasia and pulmonary hypertension.
    Pediatric research, 1988, Volume: 24, Issue:2

    Topics: Blood Pressure; Bronchopulmonary Dysplasia; Cardiac Catheterization; Cardiac Output; Child, Preschoo

1988
Nifedipine in the treatment of a child with pulmonary hypertension associated with severe bronchopulmonary dysplasia.
    Clinical pediatrics, 1986, Volume: 25, Issue:4

    Topics: Bronchopulmonary Dysplasia; Hemodynamics; Humans; Hypertension, Pulmonary; Infant; Infant, Newborn;

1986