nifedipine has been researched along with Brain Edema in 11 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion." | 7.68 | Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991) |
| "The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes." | 3.68 | Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991) |
| "The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion." | 3.68 | Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991) |
| "High-altitude pulmonary edema and high-altitude cerebral edema are potentially fatal conditions." | 2.44 | High-altitude illness and muscle physiology. ( Bosco, JA; Glassner, PJ; Weil, WM, 2007) |
| "High-altitude pulmonary edema is a non-cardiac edema that often precedes acute mountain sickness." | 2.42 | [Visiting high altitudes--healthy persons and patients with risk diseases]. ( Fischer, R, 2004) |
| "Essentially, acute mountain sickness is self-limiting and benign." | 2.41 | [Mountaineering and altitude sickness]. ( Maggiorini, M, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 6 (54.55) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luks, AM | 1 |
| McIntosh, SE | 1 |
| Grissom, CK | 1 |
| Auerbach, PS | 1 |
| Rodway, GW | 1 |
| Schoene, RB | 1 |
| Zafren, K | 1 |
| Hackett, PH | 2 |
| Fischer, R | 1 |
| Das, CJ | 1 |
| Seith, A | 1 |
| Weil, WM | 1 |
| Glassner, PJ | 1 |
| Bosco, JA | 1 |
| Buscaino, GA | 1 |
| Miyazaki, H | 1 |
| Tanaka, S | 1 |
| Fujii, Y | 1 |
| Shimizu, K | 1 |
| Nagashima, K | 1 |
| Kamibayashi, M | 1 |
| Uehara, T | 1 |
| Okuma, Y | 1 |
| Nomura, Y | 1 |
| Maggiorini, M | 1 |
| Roach, RC | 1 |
| Hirose, S | 1 |
| Handa, Y | 1 |
| Kobayashi, H | 1 |
| Kawano, H | 1 |
| Nozaki, J | 1 |
| Hayashi, M | 1 |
| Kawamura, S | 1 |
| Yasui, N | 1 |
| Shirasawa, M | 1 |
| Fukasawa, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Controlled Hyperventilation as Prophylaxis for Acute Mountain Sickness: A Randomized Controlled Trial[NCT02972411] | 30 participants (Anticipated) | Interventional | 2016-10-31 | Recruiting | |||
| Multicentric Evaluation of the Impact on Hypoxia Sensitivity of Patients With COVID-19[NCT05167357] | 90 participants (Anticipated) | Interventional | 2021-03-18 | Recruiting | |||
| Sickness Evaluation at Altitude With Acetazolamide at Relative Doses[NCT03828474] | Phase 1 | 108 participants (Actual) | Interventional | 2019-08-09 | Completed | ||
| Treatment of High-altitude Sleep Disturbance: A Double-blind Comparison of Temazepam Versus Acetazolamide.[NCT01519544] | 34 participants (Actual) | Interventional | 2012-03-31 | Completed | |||
| Acute Mountain Sickness Treatment: A Double-blind Comparison of Metoclopramide vs. Ibuprofen[NCT01522326] | 300 participants (Anticipated) | Interventional | 2012-03-01 | Completed | |||
| Can Rhodiola Crenulata Intake Improve Oxygen Saturation and Decrease the Incidence of Acute Mountain Sickness.[NCT01536288] | Phase 2 | 125 participants (Actual) | Interventional | 2010-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for nifedipine and Brain Edema
| Article | Year |
|---|---|
[Visiting high altitudes--healthy persons and patients with risk diseases].
Topics: Acclimatization; Acetazolamide; Acute Disease; Altitude; Altitude Sickness; Anti-Inflammatory Agents | 2004 |
High-altitude illness and muscle physiology.
Topics: Altitude; Anti-Inflammatory Agents; Brain Edema; Calcium Channel Blockers; Dexamethasone; Humans; Ni | 2007 |
[Mountaineering and altitude sickness].
Topics: Acetazolamide; Acute Disease; Altitude Sickness; Brain Edema; Diuretics; Glucocorticoids; Humans; Mo | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
High-altitude illness.
Topics: Acetazolamide; Altitude Sickness; Brain Edema; Calcium Channel Blockers; Diagnosis, Differential; Di | 2001 |
7 other studies available for nifedipine and Brain Edema
| Article | Year |
|---|---|
Wilderness Medical Society consensus guidelines for the prevention and treatment of acute altitude illness.
Topics: Acetazolamide; Acute Disease; Albuterol; Altitude Sickness; Brain Edema; Carbolines; Dexamethasone; | 2010 |
[Your patient wants to go to the mountains. You protect him from mountain sickness and altitude edema].
Topics: Acetazolamide; Altitude Sickness; Anticonvulsants; Brain Edema; Carbolines; Carbonic Anhydrase Inhib | 2005 |
Posterior reversible encephalopathy syndrome (PRES).
Topics: Brain Edema; Child, Preschool; Humans; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Male | 2006 |
[Medical treatment of acute disorders of cerebral circulation].
Topics: Aminophylline; Anticoagulants; Antihypertensive Agents; Brain Edema; Cerebrovascular Disorders; Cinn | 1980 |
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Prote | 1999 |
Effects of antihypertensive drugs on intracranial hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina | 1991 |
Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats.
Topics: Acute Disease; Animals; Brain; Brain Edema; Brain Ischemia; Calcium Channel Blockers; Cerebral Infar | 1991 |