nifedipine has been researched along with Bone Loss, Osteoclastic in 9 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The decrease in bone resorption correlated with an increase in [Ca2+]i." | 1.29 | Direct effect of calcium channel antagonists on osteoclast function: alterations in bone resorption and intracellular calcium concentrations. ( Fitzpatrick, LA; Maercklein, PB; Ritchie, CK, 1994) |
| " The dose-response curve for forskolin-induced bone mineral release (24 hrs), however, demonstrated a biphasic character, showing stimulation at 0." | 1.27 | Different roles for calcium and cyclic AMP in the action of PTH: studies in bone explants and isolated bone cells. ( Boonekamp, PM; Herrmann-Erlee, MP; Löwik, CW; van der Meer, JM; van Leeuwen, JP, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sashidhara, KV | 1 |
| Kumar, M | 1 |
| Khedgikar, V | 1 |
| Kushwaha, P | 1 |
| Modukuri, RK | 1 |
| Kumar, A | 1 |
| Gautam, J | 1 |
| Singh, D | 1 |
| Sridhar, B | 1 |
| Trivedi, R | 1 |
| Ritchie, CK | 1 |
| Maercklein, PB | 1 |
| Fitzpatrick, LA | 1 |
| Redlich, K | 1 |
| Pietschmann, P | 1 |
| Stulc, T | 1 |
| Peterlik, M | 1 |
| Tsuzuki, T | 1 |
| Okabe, K | 1 |
| Kajiya, H | 1 |
| Habu, T | 1 |
| Datta, HK | 2 |
| MacIntyre, I | 2 |
| Zaidi, M | 2 |
| Albers, MM | 1 |
| Johnson, W | 1 |
| Vivian, V | 1 |
| Jackson, RD | 1 |
| Patchell, A | 1 |
| Moonga, B | 1 |
| Herrmann-Erlee, MP | 1 |
| van der Meer, JM | 1 |
| Löwik, CW | 1 |
| van Leeuwen, JP | 1 |
| Boonekamp, PM | 1 |
| Yoneda, T | 1 |
| Kitamura, M | 1 |
| Ogawa, T | 1 |
| Aya, S | 1 |
| Sakuda, M | 1 |
9 other studies available for nifedipine and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Discovery of coumarin-dihydropyridine hybrids as bone anabolic agents.
Topics: Administration, Oral; Anabolic Agents; Animals; Biomarkers; Bone and Bones; Bone Density; Bone Resor | 2013 |
Direct effect of calcium channel antagonists on osteoclast function: alterations in bone resorption and intracellular calcium concentrations.
Topics: Animals; Bone Resorption; Calcium; Calcium Channel Blockers; Cells, Cultured; Intracellular Membrane | 1994 |
Comparative study on the effect of calcium channel blockers on basal and parathyroid hormone-induced bone resorption in vitro.
Topics: Amlodipine; Animals; Bone Resorption; Calcium Channel Blockers; Gallopamil; Mice; Nifedipine; Organ | 1997 |
Osmotic membrane stretch increases cytosolic Ca(2+) and inhibits bone resorption activity in rat osteoclasts.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2000 |
Intracellular calcium in the control of osteoclast function. I. Voltage-insensitivity and lack of effects of nifedipine, BAYK8644 and diltiazem.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Chronic use of the calcium channel blocker nifedipine has no significant effect on bone metabolism in men.
Topics: Adult; Aged; Bone Density; Bone Development; Bone Resorption; Case-Control Studies; Diet Records; Fe | 1991 |
'Calcium-activated' intracellular calcium elevation: a novel mechanism of osteoclast regulation.
Topics: Acid Phosphatase; Animals; Animals, Newborn; Bone Resorption; Calcium; Cells, Cultured; Ethers; Iono | 1989 |
Different roles for calcium and cyclic AMP in the action of PTH: studies in bone explants and isolated bone cells.
Topics: Animals; Bone and Bones; Bone Resorption; Calcimycin; Calcium; Cells, Cultured; Colforsin; Cyclic AM | 1988 |
Control of VX2 carcinoma cell growth in culture by calcium, calmodulin, and prostaglandins.
Topics: Animals; Bone Resorption; Calcimycin; Calcium; Calmodulin; Carcinoma; Cell Division; Cell Line; DNA | 1985 |