nifedipine has been researched along with Blood Pressure, High in 2556 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our objective was to compare cardiovascular event rates in patients with mild or moderate hypertension who received nifedipine with active drug controls." | 10.18 | Safety of nifedipine in patients with hypertension: a meta-analysis. ( Caubet, JF; Chalmers, TC; Luo, D; Niedzwiecki, D; Ross, SD; Schmid, CH; Stason, WB; Whiting, GW, 1997) |
| " Nifedipine reduces forearm vascular resistance dose-dependently when infused into the brachial artery in patients with essential hypertension, attesting to its potent arterial vasodilator effects." | 10.16 | Use of nifedipine in hypertension and Raynaud's phenomenon. ( Bühler, FR; Erne, P; Kiowski, W, 1990) |
| "We evaluated whether combined oral hydrochlorothiazide and lisinopril therapy produced superior short-term blood pressure control when compared with nifedipine among postpartum individuals with hypertension requiring pharmacologic treatment." | 9.69 | Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial. ( Amro, F; Blackwell, SC; Chauhan, SP; Fishel Bartal, M; Lawal, D; Pedroza, C; Samuel, J; Sibai, BM, 2023) |
| "The Giant PANDA study is a pragmatic, open-label, multicentre, randomised controlled trial of a treatment initiation strategy with nifedipine (calcium channel blocker), versus labetalol (mixed alpha/beta blocker) in 2300 women with pregnancy hypertension." | 9.69 | A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA). ( Ashworth, D; Battersby, C; Bick, D; Chappell, LC; Green, M; Hardy, P; Leighton, L; Magee, LA; Maher, A; McManus, RJ; Moakes, C; Morris, RK; Myers, J; Nelson-Piercy, C; Rivero-Arias, O; Sparkes, J; Webb, A; Wilson, H, 2023) |
| "The purpose is to investigate the influence of nifedipine, labetalol, and magnesium sulfate on blood pressure control, blood coagulation, and maternal and infant outcome in those suffering from pregnancy-induced hypertension (PIH)." | 9.51 | Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension. ( Gu, S; Shao, Y; Zhang, X, 2022) |
| "To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication." | 9.30 | Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019) |
| "To observe and analyze the clinical effect of nifedipine controlled-release tablets combined with valsartan in the treatment of essential hypertension, and to analyze the adverse reactions of patients." | 9.30 | Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension. ( Fu, J; Liu, W; Liu, Y, 2019) |
| "In a multicenter, randomized trial, we investigated whether the long half-time dihydropyridine calcium channel blocker amlodipine was more efficacious than the gastrointestinal therapeutic system (GITS) formulation of nifedipine in lowering ambulatory blood pressure (BP) in sustained hypertension (clinic systolic/diastolic BP 140-179/90-109 mm Hg and 24-hour systolic/diastolic BP ≥ 130/80 mm Hg)." | 9.30 | A randomized controlled trial on the blood pressure-lowering effect of amlodipine and nifedipine-GITS in sustained hypertension. ( Dou, Y; Huang, QF; Li, Y; Sheng, CS; Wang, JG; Zheng, MS; Zhu, ZM, 2019) |
| "To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension." | 9.24 | Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial. ( Greene, N; Kilpatrick, SJ; Sharma, KJ, 2017) |
| "There is a lack of sufficient evidence regarding efficacy and safety of amlodipine on treating hypertension during pregnancy." | 9.22 | Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis. ( Du, P; Mei, Z; Qin, S; Shi, S; Yin, J, 2022) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 9.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| " Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension." | 9.22 | Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022) |
| "In the present study, the efficacy and safety of oral nifedipine and intravenous labetalol for severe pre-eclampsia therapy were compared." | 9.22 | Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia. ( Shi, DD; Wang, N; Yang, FZ; Zhou, L, 2016) |
| "The aim of this study was to evaluate the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus." | 9.20 | Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F, 2015) |
| "The aim of this study was to evaluate the effects of lercanidipine or barnidipine on echocardiographic parameters, in hypertensive, type 2 diabetics with left ventricular hypertrophy." | 9.20 | Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. ( D'Angelo, A; Derosa, G; Franzetti, I; Maffioli, P; Mugellini, A; Pesce, RM; Querci, F, 2015) |
| " This study investigated the effects of a low-dose combination of nifedipine Gastrointestinal Therapeutic System (GITS) and valsartan versus high-dose monotherapy with either agent in reducing central BP in essential hypertension inadequately controlled by low-dose monotherapy." | 9.19 | Randomized trial comparing the effects of a low-dose combination of nifedipine GITS and valsartan versus high-dose monotherapy on central hemodynamics in patients with inadequately controlled hypertension: FOCUS study. ( Ha, JW; Jung, HO; Park, JB; Rhee, MY, 2014) |
| " We planned to research the effect of vitamin D and nifedipine in the treatment of patients with essential hypertension." | 9.19 | Vitamin D and nifedipine in the treatment of Chinese patients with grades I-II essential hypertension: a randomized placebo-controlled trial. ( Chen, WR; Chen, YD; Liu, ZY; Sha, Y; Shi, Y; Wang, H; Yin, DW, 2014) |
| "In this multicenter, open-label, active-controlled, parallel-group study, 564 patients with hypertension not adequately controlled by prior monotherapy were randomized to receive valsartan/amlodipine 80/5 mg or nifedipine GITS 30 mg once daily for 12 weeks." | 9.17 | Valsartan/amlodipine compared to nifedipine GITS in patients with hypertension inadequately controlled by monotherapy. ( Chen, LL; He, YS; Li, Y; Li, ZP; Wang, JG; Wei, M; Zeng, WF; Zhang, BW, 2013) |
| " In the present analysis, we used data from the TALENT study to evaluate soluble receptor for advanced glycation end-products (sRAGE) plasma levels in patients with hypertension and high-cardiovascular risk-treated nifedipine and telmisartan in combination." | 9.16 | Microalbuminuria and sRAGE in high-risk hypertensive patients treated with nifedipine/telmisartan combination treatment: a substudy of TALENT. ( Boiocchi, C; Bozzini, S; Buzzi, MP; Choi, J; D'Angelo, A; Esposito, C; Falcone, C; Mancia, G; Ochan Kilama, M; Schirinzi, S; Torreggiani, M, 2012) |
| "A retrospective analysis of the database from A Coronary Disease Trial Investigating Outcome with Nifedipine (ACTION) evaluated the effectiveness of nifedipine gastrointestinal therapeutic system (GITS) (i) in combination with renin angiotensin system (RAS) blockers and (ii) in patients with isolated systolic hypertension (ISH)." | 9.15 | Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina. ( Elliott, HL; Meredith, PA, 2011) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 9.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "We compared antihypertensive effects and organoprotective action of a calcium antagonist nifedipine RD and angiotensin converting enzyme (ACE) inhibitor enalapril in subjects older than 60 years with systolic diastolic (group 1) and isolated (group 2) I-II degree arterial hypertension." | 9.14 | [Comparative assessment of a calcium antagonist with controlled release of nifedipine and enalapril in arterial hypertension in subjects older than 60 years]. ( Borisova, NA; Fadeeva, SS; Grishaeva, EE; Iastrebova, EI; Oleĭnikov, VE, 2009) |
| " This trial investigated the antihypertensive efficacy and effects on the morning BP surge of awakening versus bedtime administration of nifedipine in essential hypertension." | 9.14 | Reduction of morning blood pressure surge after treatment with nifedipine GITS at bedtime, but not upon awakening, in essential hypertension. ( Alonso, I; Ayala, DE; Fernández, JR; Hermida, RC; Mojón, A, 2009) |
| "This study investigated the effectiveness and tolerability of barnidipine 10 or 20 mg added to losartan 50 mg versus losartan 100 mg alone in patients with mild to moderate essential hypertension whose BP was uncontrolled by losartan 50-mg monotherapy." | 9.14 | Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-grou ( Cagnoni, F; Destro, M; Giglio, A; Grandi, AM; Lonati, L; Maresca, AM; Monza, M; Omboni, S; Parati, G; Pini, C; Ricci, AR; Venco, A, 2010) |
| "In this study, we primarily aimed to identify the acute effects of hypertension on fibrinolytic function in previously untreated urgent hypertensive patients and to evaluate the influence of two commonly used, short-acting, anti-hypertensive agents, captopril and nifedipine, in these patients." | 9.14 | Plasma plasminogen activator inhibitor 1 (PAI-1) and P-selectin levels in urgent hypertension: effect of single dose captopril and nifedipine on fibrinolytic activity. ( Buyukhatipoglu, H; Tiryaki, O; Usalan, C, 2010) |
| "The aim of this study was to compare nifedipine and carvedilol in the treatment of de novo arterial hypertension after orthotopic liver transplantation (OLT)." | 9.13 | Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial. ( Angeli, P; Boccagni, P; Cillo, U; Fasolato, S; Frigo, AC; Galioto, A; Gatta, A; Semplicini, A; Sticca, A; Zanus, G, 2008) |
| "The TOlerabilidad de LERcanidipino 20 mg frente a Amlodipino y Nifedipino en CondicionEs normales de uso study was aimed to compare the tolerability of high doses of lercanidipine with amlodipine and nifedipine gastro-intestinal therapeutic system (GITS) in the treatment of hypertension in daily clinical practice." | 9.13 | High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study. ( Barrios, V; Calderón, A; de la Figuera, M; Escobar, C; Honorato, J; Llisterri, JL; Segura, J, 2008) |
| "We investigated whether long-term treatment with the angiotensin-converting enzyme (ACE) inhibitor imidapril or the calcium channel antagonist nifedipine increases systemic nitric oxide (NO) production in patients with essential hypertension." | 9.12 | Long-term treatment with imidapril but not with nifedipine enhances plasma NOx concentration in patients with essential hypertension. ( Horiuchi, M; Kouzuma, R; Mizuki, T; Morishita, T; Nakashima, Y; Nakata, S; Okazaki, M; Suda, O; Sumiyama-Fujinishi, A; Tasaki, H; Tsutsui, M; Yanagihara, N, 2006) |
| "In patients with MS and mild hypertension monotherapy with spirapril and combination of spirapril with nifedipine retard caused lowering of BP to target level in 55 and 90%, respectively." | 9.12 | [Rational approach to selection of antihypertensive therapy in persons with metabolic syndrome: efficacy of monotherapy with spirapril and its combination with retard form of nifedipine]. ( Kiseleva, NV; Mamedov, MN, 2006) |
| "Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation." | 9.12 | Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension. ( Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A, 2007) |
| "We examined the effect of a Ca antagonist (nilvadipine) on the occurrence or recurrence of symptomatic stroke in hypertensive patients with MRI-defined asymptomatic cerebral infarction (ACI), periventricular hyperintensity (PVH), and deep and subcortical white matter hyperintensity (DSWMH), with or without a history of stroke, and evaluated the effect of long-term treatment on the lesions." | 9.12 | Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment. ( Fukuuchi, Y; Hirai, S; Okudera, T; Shinohara, Y; Terashi, A; Tohgi, H; Yamaguchi, T, 2007) |
| "Amlodipine and nifedipine CR were administered to 41 patients with essential hypertension for more than 6 weeks each in a randomized open-label crossover study." | 9.12 | Crossover study of amlodipine versus nifedipine CR with home blood pressure monitoring via cellular phone: internet-mediated open-label crossover trial of calcium channel blockers for hypertension (i-TECHO trial). ( Itagaki, K; Nakajima, S; Nakamoto, H; Nishida, E; Ryuzaki, M; Sone, M; Suzuki, Y; Yoshimoto, M, 2007) |
| " This multicenter, randomized, double-blind study was aimed at testing the efficacy and safety of the combination of low-dose nifedipine GITS 20 mg/ losartan 50 mg compared with either monotherapy in patients with grade 1 to 3 hypertension over an eight-week period." | 9.11 | Effects of the combination of low-dose nifedipine GITS 20 mg and losartan 50 mg in patients with mild to moderate hypertension. ( Bendersky, M; Grassi, G; Guzman, L; Kuschnir, E; Mancia, G; Pañart, MS; Plotquin, Y; Resk, J; Wagener, G, 2004) |
| "The Japan Multicenter Investigation for Cardiovascular Diseases-B was performed to investigate whether nifedipine retard treatment was associated with a significantly higher incidence of cardiac events than angiotensin converting enzyme inhibitor treatment in Japanese patients." | 9.11 | Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial. ( Arakawa, K; Hirayama, A; Hosoda, S; Iimura, O; Ishii, M; Kanmatsuse, K; Kawai, C; Kodama, K; Nonogi, H; Origasa, H; Saruta, T; Sumiyoshi, T; Yui, Y, 2004) |
| "We evaluated the effects of 4 weeks of treatment with low-dose nifedipine gastrointestinal therapeutic system (GITS; 20 mg/day) compared with placebo on muscle sympathetic nerve activity and plasma noradrenaline, in relation to changes in plasma renin activity and plasma angiotensin II and blood pressure in young and older patients with mild hypertension." | 9.11 | Effects of low-dose nifedipine GITS on sympathetic activity in young and older patients with hypertension. ( Coletta, E; Floras, J; Leenen, FH; Ruzicka, M, 2004) |
| "This study was conducted to evaluate blood pressure control glucose homeostasis, and the plasma lipid profile in patients with type 2 diabetes mellitus and mild hypertension during 12 months of treatment with the ARB telmisartan or nifedipine gastrointestinal therapeutic system (GITS)." | 9.11 | Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doubl ( Bertone, G; Ciccarelli, L; Cicero, AF; Derosa, G; Fogari, E; Fogari, R; Piccinni, MN, 2004) |
| "To assess the efficacy of an angiotensin converting enzyme (ACE) inhibitor (perindopril), a dihydropyridine calcium channel blocker (sustained release nifedipine) and placebo in preventing the progression of albuminuria and decline in glomerular filtration rate (GFR) in patients with Type 2 diabetes and microalbuminaria." | 9.11 | Long-term renoprotection by perindopril or nifedipine in non-hypertensive patients with Type 2 diabetes and microalbuminuria. ( Allen, TJ; Campbell, DJ; Cooper, ME; Gilbert, RE; Hammond, JJ; Jerums, G; O'Brien, RC; Raffaele, J; Tsalamandris, C, 2004) |
| "This study tested the effects on cardiovascular outcomes of treatments based on nifedipine gastrointestinal therapeutic system (GITS) compared with the diuretic combination co-amilozide in a pre-specified subset of patients with isolated systolic hypertension (ISH) enrolled in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT) study." | 9.11 | Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study. ( Brown, M; Castaigne, A; De Leeuw, P; Mancia, G; Palmer, C; Rosental, T; Ruilope, L; Wagener, G, 2004) |
| "These findings suggest that the low-dose combination therapy of nifedipine CR and candesartan is superior to the up-titrated monotherapy of candesartan in terms of blood pressure control and renal protection in patients with essential hypertension." | 9.11 | Controlled-release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: the NICE Combi (Nifedipine and Candesartan Combination) Study. ( Hasebe, N; Kikuchi, K, 2005) |
| "The salutary effects of the addition of nifedipine GITS to the basic regimen of patients with concurrent stable symptomatic coronary artery disease and hypertension emphasize the need for blood pressure control." | 9.11 | Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension: the ACTION trial. ( de Brouwer, S; Kirwan, BA; Lubsen, J; Poole-Wilson, PA; Wagener, G, 2005) |
| "This randomized, double-blind, multicentre trial compared the blood pressure lowering effects of a 12-week treatment of nifedipine GITS 20 mg vs enalapril 20 mg in 264 patients with mild-to-moderate hypertension." | 9.11 | Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension. ( Agabiti Rosei, E; Morelli, P; Rizzoni, D, 2005) |
| "To compare the efficacy and tolerability of bisoprolol, enalapril and nifedipine retard in the treatment of mild to moderate essential hypertension." | 9.10 | Efficacy of domestic bisoprolol,enalapril and nifedipine retard in mild to moderate hypertension: a randomized double-blind multicenter clinical trial in China. ( Li, M; Liu, G; Shi, X, 2002) |
| "The purpose of this study was to determine whether the slower- and longer-acting nifedipine tablets were as effective and safe as the rapid onset and short-acting nifedipine capsules for the treatment of acute severe hypertension in pregnancy." | 9.10 | Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002) |
| "To investigate the changes of coagulation and fibrinolysis status in patients with essential hypertension (EH) and observe the therapeutic effect of sustained-release nifedipine." | 9.10 | [Coagulative and fibrinolytic changes in patients with essential hypertension and the effect of sustained-release nifedipine]. ( Chi, DS; Ge, B; Hong, XS; Jin, FX; Su, YW; Wu, BM; Yang, SG; Yu, RS, 2002) |
| "We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)." | 9.10 | Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002) |
| "To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension." | 9.10 | Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003) |
| "To compare the effectiveness, safety and tolerability of once-daily nifedipine and amlodipine treatment in patients with mild-to-moderate essential hypertension." | 9.10 | Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine. ( Caglar, N; Canberk, A; Deger, N; Demirtas, M; Dortlemez, H; Kes, S; Kiliccioglu, B; Kozan, O; Ovunc, K; Turkoglu, C, 2003) |
| "This study aimed to compare the effects of two long-acting dihydropyridine calcium channel blockers (CCBs) with different pharmacologic properties, lercanidipine and nifedipine Gastro-Intestinal Therapeutic System (GITS), in the chronic treatment of essential hypertension." | 9.10 | Differential effects of lercanidipine and nifedipine GITS on plasma norepinephrine in chronic treatment of hypertension. ( Corradi, L; Derosa, G; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2003) |
| "To compare efficacy and safety of nifedipin-retard (cordaflex-retard, Egis, Hungary) used in monotherapy and in combination with metoprolol (egilok, Egis, Hungary) in patients with arterial hypertension (AH)." | 9.10 | [Assessment of the efficacy and tolerance of delayed-action nifedipine as the monotherapy or in combination with metoprolol in patients with arterial hypertension]. ( Andreeva, GF; Dmitrieva, NA; Gorbunov, VM; Isaĭkina, OIu; Martsevich, SIu, 2003) |
| "The International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT) showed, by means of office blood pressure measurements, that long-term treatment with nifedipine GITS is as effective as diuretics in preventing cardiovascular and cerebrovascular complications." | 9.10 | Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Mancia, G; Omboni, S; Parati, G, 2002) |
| "The objective of this study was to compare the safety and efficacy of nifedipine in two different formulations (osmotic pump and slow release microgranules) in patients with essential hypertension." | 9.10 | Efficacy and safety of two different formulations of nifedipine (GITS) vs. slow release microgranules in patients with mild and moderate hypertension. ( Aroca, G; Asa, G; Botero, R; González, M, 2002) |
| "To evaluate the appropriate dosing of amlodipine when converting patients from nifedipine extended-release (nifedipine ER) to amlodipine in the treatment of hypertension." | 9.09 | Evaluation of amlodipine dosing for conversion of nifedipine extended-release to amlodipine in the treatment of hypertension. ( Enlow, AM; Halverson, VJ; Kilpatrick, DM; Lower, DL; Montopoli, G; Yamreudeewong, W, 1999) |
| "The aim of this study was to evaluate the effect of trandolapril, an angiotensin converting enzyme inhibitor, on blood pressure, forearm blood flow and insulin sensitivity in comparison with nifedipine gastrointestinal therapeutic system." | 9.09 | Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS). ( Capaldo, B; Carretta, R; Fabris, F; Ferrara, LA; Galletti, F; Glorioso, N; Mancini, M; Semplicini, A; Strazzullo, P, 1999) |
| "We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy." | 9.09 | A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies." | 9.09 | A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. ( Chauhan, SP; Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy." | 9.09 | Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000) |
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 9.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "With the aim of evaluating the effects on blood pressure, platelet function and insulin sensitivity of the dihydropiridines lacidipine and nifedipine GITS, a parallel double-blind study was carried out in a group of 20 patients with mild to moderate essential hypertension." | 9.09 | Effect of lacidipine and nifedipine GITS on platelet function in patients with essential hypertension. ( Armas-Hernández, MJ; Armas-Padilla, MC; Carvajal, AR; Castillo-Moreno, A; Hernández-Hernández, R; Pacheco, B; Velasco, M, 2000) |
| " We compared the effects of the calcium-channel blocker nifedipine once daily with the diuretic combination co-amilozide on cardiovascular mortality and morbidity in high-risk patients with hypertension." | 9.09 | Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Brown, MJ; Castaigne, A; de Leeuw, PW; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM, 2000) |
| "This double-blind, parallel group study compared the effect of nifedipine gastrointestinal transport system (GITS) (L-type CCB) versus mibefradil (T-type CCB) on ANS function in patients with mild-moderate essential hypertension." | 9.09 | Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension. ( Esler, MD; Kamen, PW; Krum, H; Lim, S; Pellizzer, AM, 2001) |
| "This study was undertaken to determine if adult patients with mild to moderate essential hypertension whose blood pressure had been controlled for > or = 3 months with nifedipine GITS 30 mg could be successfully switched to a 20-mg daily dose with continued antihypertensive efficacy." | 9.09 | Blood pressure control in patients with mild to moderate essential hypertension switched from nifedipine gastrointestinal therapeutic system (GITS) 30 mg to nifedipine GITS 20 mg. ( Toal, CB, 2001) |
| "Candesartan, an AT(1) receptor antagonist, has been reported to have no association with persistent cough in subjects with hypertension, but there has been no study on the safety of its administration to hypertensive patients with symptomatic asthma." | 9.09 | Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma. ( Abe, S; Hashimoto, M; Oashi, K; Saikai, T; Suzuki, K; Tanaka, H; Tanaka, S; Teramoto, S, 2001) |
| "The effect of quinapril and nifedipine on platelet aggregation, vascular endothelial function and coagulation system activity, was compared in a parallel-group, investigator-blind study carried out on patients with mild to moderate hypertension but no other diseases or receiving medication which might affect platelet function, vascular endothelium or coagulation." | 9.09 | A single (investigator)-blind randomised control trial comparing the effects of quinapril and nifedipine on platelet function in patients with mild to moderate hypertension. ( Bareford, D; Beevers, DG; Islim, IF, 2001) |
| "In this 1-year clinical study, we compared the efficacy and tolerability of amlodipine and nifedipine retard in 64 Chinese Type 2 diabetic patients with hypertension." | 9.09 | Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial. ( Chan, CH; Chan, HC; Ko, GT, 2001) |
| "The main purpose of this study was to compare efficacy, tolerability and influence on quality of life (QOL) of nifedipine gastrointestinal therapeutic system (NI) 30-60 mg once a day vs amlodipine (AM) 5-10 mg once a day in elderly patients with mild-moderate hypertension." | 9.09 | Efficacy, tolerability and influence on "quality of life" of nifedipine GITS versus amlodipine in elderly patients with mild-moderate hypertension. ( Boari, L; De Dominicis, E; Giusti, C; Kilama, MO; Marchesi, M; Marelli, G; Mattarei, M; Mos, L; Novo, S; Pessina, AC; Pirrelli, A; Santini, M; Santonastaso, M; Semeraro, S; Uslenghi, E, 2001) |
| " A single centre, prospective, randomised, double-blinded, comparative study to address the efficacy of controlled release nifedipine or lisinopril in the treatment of hypertension (diastolic blood pressure > or =95 mmHg) in cyclosporin (CsA)-treated renal transplant recipients was performed." | 9.09 | Efficacy of nifedipine or lisinopril in the treatment of hypertension after renal transplantation: a double-blind randomised comparative trial. ( Fauchald, P; Hartmann, A; Holdaas, H; Midtvedt, K, 2001) |
| "To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)." | 9.09 | [The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000) |
| "The purpose of the study was to compare the effect of treatment with an angiotensin converting enzyme inhibitor (Lisinopril, MSD) or calcium blocker (Nifedipine retard, MSD) treatment during three months on blood pressure (measured with sphygmomanometric method and ambulatory blood pressure monitoring--ABPM) and urinary albumin excretion in essential hypertension class I acc." | 9.08 | [Comparison of treatment effects with an angiotensin converting enzyme inhibitor--lisinopril and a calcium blocker--nifedipine retard on urinary albumin excretion in patients with non-complicated essential hypertension]. ( Celibała, R; Czekalski, S; Widecka, K, 1995) |
| "Patients with controlled hypertension (diastolic blood pressure less than 90 mmHg) on nifedipine-PA 10 mg (n = 74) or 20 mg (n = 99) bid were enrolled into an open label study consisting of six weeks of previous nifedipine-PA followed by six weeks of nifedipine-GITS therapy." | 9.08 | Comparative efficacy of two long-acting formulations of nifedipine in the treatment of hypertension. The Switch Study Investigators. ( Myers, MG; Toal, CB, 1995) |
| "A multicenter, controlled, open, randomized trial of antihypertensive and life quality (LQ) effects of monotherapy with captopril vs propranolol, hydrochlorothiazide and nifedipine included 345 males aged 35-60 years with mild and moderate hypertension." | 9.08 | [The effect of long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents on the quality of life in patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working ( Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, J; Vygodin, VA, 1995) |
| "To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 9.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
| " In nine hypertensive patients with enalapril-induced cough the effect of altering the dose of enalapril on subjective cough and the cough response to inhaled capsaicin was examined in a random single-blind balanced cross-over study." | 9.08 | Effect of dose adjustment on enalapril-induced cough and the response to inhaled capsaicin. ( Foster, G; Higgins, KS; Jackson, PR; Ramsay, LE; Yeo, WW, 1995) |
| "To examine the central hemodynamic and blood gas responses to sublingual captopril and nifedipine administration in patients with arterial hypertension after abdominal aortic surgery." | 9.08 | Invasive hemodynamic evaluation of sublingual captopril and nifedipine in patients with arterial hypertension after abdominal aortic surgery. ( Degaute, JP; Leeman, M, 1995) |
| "Evaluation of the efficacy and tolerability of nifedipine oros in patients with mild to moderate essential hypertension without major target organ damage and the anti-hypertensive effect along the 24 hours." | 9.08 | [Multicenter National Study for the evaluation of the efficacy and tolerance of nifedipine oral release osmotic system in mild to moderate hypertension]. ( Amodeo, C; Ayoub, JC; Brandão, AP; Chaves, H; de Andradre, J; Giorge, DM; Lima Júnior, E; Mion Júnior, D; Nobre, F; Ribeiro, JM, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 9.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| " The medication of 39 patients with hypertension was changed from once-daily diltiazem hydrochloride (Cardizem CD) or nifedipine (Procardia XL) to felodipine (Plendil)." | 9.08 | Felodipine as an alternative to more expensive calcium antagonists in mild to moderate hypertension. ( Horwhat, JD; Landry, FJ; Pinski, L; Tomich, D, 1996) |
| "The effect of nifedipine in the treatment of hypertensive venous leg ulcers was studied on 30 outpatients in a double-blind placebo-controlled trail over a period of 2 months." | 9.08 | Treatment of hypertensive venous leg ulcers with nifedipine. ( Nikolova, K, 1995) |
| " Thus, a group of 76 consecutive patients with mild-to-moderate hypertension and chronic obstructive pulmonary disease (COPD) were selected to participate in a clinical antihypertensive trial to define the roles of lisinopril, nifedipine and conventional therapy, and their impact on the renin-antiotensin system (RAS)." | 9.08 | Comparisons of long-term effects of lisinopril vs nifedipine vs conventional therapy in the treatment of mild-to-moderate hypertension in patients with chronic obstructive pulmonary disease. ( Chiang, HT; Lee, D; Lin, M; Yang, YF, 1996) |
| " The aim of the study was to assess effects of sublingual 10 mg nifedipine (n = 15) or 25 mg captopril (n = 13) on HRV in consecutive patients admitted to hospital due to severe hypertension." | 9.08 | Nifedipine and captopril exert divergent effects on heart rate variability in patients with acute episodes of hypertension. ( Ceremuzynski, L; Kulakowski, P; Wolk, R, 1996) |
| "To compare the efficacy and tolerance of felodipine-ER and nifedipine OROS, both once daily, in the treatment of mild-to-moderate uncomplicated arterial hypertension (AH)." | 9.08 | [Multicenter comparative study of felodipine-ER and nifedipine-OROS in the treatment of mild-to-moderate arterial hypertension]. ( Armaganijan, D; Batlouni, M; Castro, I; Chaves Junior, Hde C; Leite Luna, R; Nobre, F; Pereira da Cunha, C; Silveira Sbissa, A, 1996) |
| " In this double-blind forced titration study design we compared the effects of mibefradil 50, 100, and 150 mg and nifedipine GITS 30, 60, and 90 mg monotherapies or combined with lisinopril 20 mg in 71 moderate to severe hypertensives (59 men and 12 women) with confirmed ambulatory hypertension." | 9.08 | The antihypertensive efficacy of the novel calcium antagonist mibefradil in comparison with nifedipine GITS in moderate to severe hypertensives with ambulatory hypertension. ( Archambault, F; Dalle Ave, S; Lacourcière, Y; Lefebvre, J; Lindberg, E; Poirier, L; Ward, C, 1997) |
| "Both felodipine ER and nifedipine Retard are effective "add-on' drugs in patients with monotherapy-resistant hypertension." | 9.08 | Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring. ( Breed, JG; Dees, A; Kremer Hovinga, T; Meems, L; Puister, SM; Verstappen, VM, 1997) |
| "To investigate the 24-hour efficacy of nilvadipine (8 and 16 mg)in patients with mild to moderate essential hypertension, a double-blind, randomized, placebo-controlled, multicenter study with 3 parallel medication groups (placebo, 8, and 16 mg nilvadipine) was performed." | 9.08 | Nilvadipine in hypertension--experience in ambulatory treatment. ( Burkardt, I; Hoffmann, A; Kraul, H, 1997) |
| "The potential role of endothelin-1 (ET-1) in essential hypertension in humans is still subject to debate." | 9.08 | Endothelin-1-induced vasopressor responses in essential hypertension. ( Kaasjager, KA; Koomans, HA; Rabelink, TJ, 1997) |
| "Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy." | 9.08 | Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997) |
| "Because blood viscosity is significantly raised in patients with essential hypertension (EH), the hemorheological effects of a 4-month chronic treatment with the calcium antagonist nilvadipine (FK 235, 5-isopropyl-3-methyl-2-cyano-1,4-dihydro-6-methyl-4- (m-nitrophenyl)-3,5-pyridinedicarboxylate, CAS 75530-68-6) on elevated blood viscosity was investigated prospectively in patients with EH, and compared with those in normotensive individuals of similar age." | 9.08 | Chronic hemorheological effects of the calcium antagonist nilvadipine in essential hypertension. ( Izumi, Y; Kitadai, M; Satoh, K; Takahashi, T; Tsuda, Y, 1997) |
| "Quality of life with the selective beta1-blocker bisoprolol and the calcium channel blocker nifedipine as a retard formulation was compared in patients with essential hypertension." | 9.08 | Quality of life comparison between bisoprolol and nifedipine retard in hypertension. ( de Hoon, JN; Van Bortel, LM; van de Ven, LL; Vanmolkot, FH, 1997) |
| " This study assessed the efficacy and safety of nifedipine GITS (oral release osmotic system) as monotherapy, in addition to the effects on left ventricular hypertrophy, after a long term follow-up (one year)." | 9.08 | [Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle]. ( Arocha, I; Arreaza, MR; Bustillo, N; Corral, JL; García, P; López, NC; Perozo, M, 1997) |
| "The purpose of the study was to compare the antianginal and hypotensive efficacy and tolerability of 8 weeks of treatment with amlodipine taken once daily and nifedipine taken twice daily in patients with stable exertional angina pectoris and mild-to-moderate hypertension." | 9.08 | [Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension]. ( Hlawaty, M; Kubler, G; Negrusz-Kawecka, M; Olszowska, M; Salamon, P; Tracz, W; Witkowska, M, 1997) |
| "Nifedipine GITS was superior to enalapril in controlling ambulatory blood pressure, but they were equivalent in reducing proteinuria (37%)." | 9.08 | Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt. ( DeQuattro, V; Lee, DP, 1997) |
| "MIBEFRADIL IN THE TREATMENT OF HYPERTENSION: The antihypertensive efficacy of mibefradil, a new selective transient (T)-channel calcium antagonist, was studied in eight randomized, double-blind, parallel-design trials: four placebo-controlled and four active drug-controlled versus other calcium antagonists." | 9.08 | Differential properties of mibefradil in hypertension and angina. ( Kobrin, I, 1997) |
| "The antihypertensive efficacy and safety of mibefradil and nifedipine SR were compared in 143 patients with chronic renal failure and mild-to-moderate hypertension in a multicenter, double-blind, randomized, parallel-design study." | 9.08 | A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. ( Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ, 1998) |
| "To evaluate the 24 h antihypertensive efficacy and duration of action of felodipine extended release (ER) in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system (GITS), in patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure (BP) monitoring." | 9.08 | Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study. ( Archambault, F; Jewell, D; Lacourcière, Y; Lefebvre, J; Poirier, L; Reed, CV, 1998) |
| "Since both agents were equally effective in reducing both SBP and DBP and reserpine is much cheaper than nifedipine, it is recommended that for a developing country like Zimbabwe, the combination of HCT and reserpine at the above doses should be used as the first step to treat mild to moderate hypertension without evidence of end organ damage." | 9.08 | A randomised crossover comparison of reserpine and sustained-release nifedipine in hypertension. ( Manyemba, J, 1997) |
| " The purpose of this study was to assess the risk ratio for cancer mortality associated with nifedipine in a large population of patients post-myocardial infarction." | 9.08 | Nifedipine and cancer mortality: ten-year follow-up of 2607 patients after acute myocardial infarction. ( Behar, S; Boyko, V; Goldbourt, U; Jonas, M; Mandelzweig, L; Reicher-Reiss, H, 1998) |
| "To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy." | 9.08 | Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998) |
| "To assess the effect of 1-year treatment with rilmenidine, an oxazoline compound that exerts its antihypertensive effects through binding to imidazoline receptors in the brainstem, on left ventricular hypertrophy (LVH) secondary to essential, mild-to-moderate hypertension [supine diastolic blood pressure (DBP)95-115 mmHg]." | 9.08 | Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study. ( Balazovjech, I; Dubai, G; Dvorak, I; Januszewicz, W; Krupa-Wojciechowska, B; Kubasik, A; Kuch-Wocial, A; Polak, G; Sadowski, Z; Simon, K; Stejfa, M; Szwed, H, 1998) |
| " Among these trials, the International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT) is of special interest because it is the first study to address, in a prospective fashion, the prognostic influence of antihypertensive treatment (nifedipine GITS vs a combined thiazide and potassium-sparing diuretic) in hypertensive patients with concomitant risk factors such as hypercholesterolemia, cigarette smoking, diabetes, and left ventricular hypertrophy." | 9.08 | The International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT) trial. ( Grassi, G; Mancia, G, 1998) |
| "To ascertain the baseline characteristics of the high-risk hypertensive patients entering the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT)." | 9.08 | Study population and treatment titration in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Brown, MJ; Castaigne, A; de Leeuw, PW; Mancia, G; Rosenthal, T; Ruilope, LM, 1998) |
| "Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs." | 9.08 | Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998) |
| "The efficacy and acceptability of 5 mg nebivolol once daily, a long-acting, vasodilating cardioselective beta blocker that additionally facilitates the L-arginine/nitric oxide system, was assessed in a double-blind, randomized trial in comparison with 20 mg nifedipine retard twice daily in patients with essential hypertension." | 9.08 | Nebivolol versus nifedipine in the treatment of essential hypertension: a double-blind, randomized, comparative trial. ( Dupont, AG; Korlipara, K; Lacourcière, Y; Marcadet, DM; Robertson, JI; Van Nueten, L; Vyssoulis, G, 1998) |
| "To investigate the effect of amlodipine, nifedipine and perindopril on insulin sensitivity(IS) and blood lipid of patients with essential hypertension(EH)." | 9.08 | [The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension]. ( Chen, D; Lin, J; Wu, K, 1998) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 9.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| "The present study was performed to investigate the efficacy and safety of the angiotensin converting enzyme (ACE) inhibitor lisinopril compared with those of the calcium channel blocker nifedipine in 293 patients with mild to moderate essential hypertension (supine diastolic blood pressure (DBP) 95-115 mmHg) in a multicentre, randomised, double-blind parallel group study after a two week single-blind placebo run-in period." | 9.07 | Lisinopril versus slow release nifedipine in patients with essential hypertension: a multicentre study. ( Kramer, HJ; Predel, HG, 1994) |
| "In a double-blind double-dummy multicenter study, patients with mild to moderate essential hypertension were randomized to receive either nifedipine (n = 416, 47." | 9.07 | Female preponderance for lisinopril-induced cough in hypertension. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1994) |
| "To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)." | 9.07 | A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994) |
| "The therapeutic efficacy of long acting diltiazem 300 mg od (Tildiem LA) was compared with sustained release nifedipine 20 mg bd and bendrofluazide 5 mg od in a multicentre study with 230 patients diagnosed with mild to moderate essential hypertension, with 77, 77 and 76 randomized to the diltiazem, nifedipine SR and bendrofluazide groups respectively." | 9.07 | A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension. ( Belgrave, GP; Hosie, J; Nasar, MA; Walters, EG, 1994) |
| "To evaluate the antihypertensive efficacy and safety of cilazapril compared to nifedipine retard in mild to moderate hypertension." | 9.07 | [Comparative and double-blind study of the efficacy and safety of cilazapril compared to nifedipine retard in the treatment of mild and moderate arterial hypertension]. ( Athanázio-Heliodoro, RC; Franco, RJ; Marcondes, M; Martin, LC; Mion Júnior, D; Pascoal, IJ; Sampaio, M; Tinucci, T; Velasco-Cornejo, IF, 1994) |
| "Lisinopril has been compared with slow-release nifedipine in a 16-week double-blind, randomized, parallel-group study involving 102 patients with mild to moderate hypertension." | 9.07 | A comparison of lisinopril and nifedipine in the treatment of mild to moderate hypertension. A multicentre study. ( Rogstad, B, 1994) |
| "Nineteen patients with essential hypertension on regular treatment with nifedipine tablets 20 mg twice daily and whose DBP was < 95 mmHg on at least two occasions two weeks apart were entered in a double-blind randomised crossover study of three weeks treatment with nifedipine coat core (new formulation) either as 30 mg one daily or as 60 mg once daily dose." | 9.07 | Double-blind crossover study of once daily nifedipine coat core in essential hypertension. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Missouris, CG; Singer, DR, 1994) |
| "Evaluation of the effects of nilvadipine on nifedipine-induced lower-leg edema." | 9.07 | [Effect of nilvadipine on nifedipine-induced edema of the lower leg. Results of a double-blind randomized comparative study]. ( Schmitt, W; Vollmuth, M, 1994) |
| " The hemodynamic responses to captopril 25 mg SL (n = 10) and to nifedipine 10 mg SL (n = 10) were studied for 2 hours in patients (mean age 66 years) with arterial hypertension (mean blood pressure, Pa > or = 115 mmHg) the day after abdominal aortic surgery." | 9.07 | [Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually]. ( Degaute, JP; Leeman, M, 1993) |
| "The efficacy of lisinopril 10-40 mg once daily was compared with that of nifedipine tablets 20-40 mg twice daily in a multicentre double-blind randomized parallel group study of 16 weeks duration involving 127 patients with mild to moderate hypertension." | 9.07 | ACE inhibition versus calcium antagonism in the treatment of mild to moderate hypertension: a multicentre study. Ireland-Netherlands Lisinopril-Nifedipine Study Group. ( Clarke, RJ; Hart, W, 1993) |
| " We measured lymphocyte and serum magnesium and potassium in 28 patients treated for hypertension for 6 months with nifedipine or captopril." | 9.07 | Effect of prolonged nifedipine or captopril therapy on lymphocyte magnesium and potassium levels in hypertension. ( Daly, K; Finn, J; Grimes, H; Lavin, F; Mannion, A; O'Keeffe, S, 1993) |
| "Nifedipine is an effective compound for the treatment of hypertension." | 9.07 | Double-blind comparison between nifedipine and amlodipine for the treatment of essential hypertension. ( Cappuccio, FP; Carney, C; Crane, M; MacGregor, GA; Markandu, ND; Singer, DR, 1993) |
| "55 g/day of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on BP and serum lipids were assessed in 18 males with hypertension (WHO stage I-II)." | 9.07 | Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension. ( Eritsland, J; Hjermann, I; Hysing, J; Landmark, K; Mundal, HH; Thaulow, E, 1993) |
| "The antihypertensive efficacy of single-drug therapy with nifedipine (N), prazosin (P), or acebutolol (A) and the influence of these agents on coronary risk factors including hypoglycemia, hyperuricemia, and hyperlipidemia, were studied in adolescents with hypertension." | 9.07 | [Evaluation of the efficacy and tolerance of three antihypertensive agents used as single-drug therapy, nifedipine, prazosin and acebutolol in severe, idiopathic hypertension in adolescents]. ( Cichocka, E; Januszewicz, P; Wyszynska, T, 1993) |
| "Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation." | 9.07 | Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993) |
| "An interim analysis of patient compliance is reported in 234 hypertension outpatients who were entered into a large-scale, open, crossover, comparative study between a new-generation calcium antagonist, amlodipine (5 mg, once daily), and nifedipine SR (20 mg, twice daily)." | 9.07 | Patient compliance and therapeutic coverage: amlodipine versus nifedipine SR in the treatment of hypertension and angina: interim results. Steering Committee and Cardiologists and General Practitioners involved in the Belgium Multicentre Study on Patient ( Detry, JM, 1994) |
| "to compare lisinopril and nifedipine in the management of essential hypertension in 52 patients in general practice with respect to the obtaining of target diastolic blood pressure and freedom from side effects." | 9.07 | A comparative trial of lisinopril and nifedipine in mild to moderate hypertension in general practice. ( Murdoch, JC, 1992) |
| "In a randomized, parallel, double-blind study, lisinopril (n = 412) reduced systolic and diastolic blood pressure more than nifedipine did (n = 416) after ten weeks treatment in patients (40-70 years) with mild to moderate essential hypertension." | 9.07 | [Treatment with lisinopril or nifedipine in essential hypertension. A Norwegian multicenter study of the effect, tolerance and quality of life of 828 patients]. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1992) |
| "The purpose of this placebo-control, double-blind, randomized and crossover study is to evaluate the effect of nicardipine and nifedipine in Chinese senile hypertension." | 9.07 | [Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study]. ( Chang, MS; Chen, CH; Chen, JW; Wang, SP, 1992) |
| "The safety and tolerability of carvedilol, a new antihypertensive agent with the combined pharmacological activities of beta-blockade and vasodilation, and of nifedipine were investigated in patients with essential hypertension and non-insulin-dependent (type II) diabetes mellitus." | 9.07 | Comparison of the effects of carvedilol and nifedipine in patients with essential hypertension and non-insulin-dependent diabetes mellitus. ( Adezati, L; Albergati, F; Boeri, D; Lombardo, I; Paternó, E; Semino, S; Venuti, RP; Viviani, GL, 1992) |
| "QUERY: Influence of Nilvadipine, a new calcium channel blocker on the daytime blood pressure profile and 24-hour blood pressure values in patients with mild-to-moderate hypertension." | 9.07 | [Effect of nilvadipine on diurnal blood pressure profile. Use of a new calcium channel blocker in mild to intermediate hypertension]. ( Keck, M; Quitzdorff, G, 1992) |
| "Nitrendipine (bypress) manufactured by Bayer Company in the form of 10 and 20 mg tablets and administered in a dose of 20-40 mg/day turned out an effective antihypertensive remedy in 65% of patients with arterial hypertension largely running a mild course." | 9.07 | [The efficacy of nitrendipine in patients with stable arterial hypertension. The data from a cooperative study in the USSR. The Working Group for the Cooperative Study of Nitrendipine]. ( Metelitsa, VI; Ostrovskaia, TP, 1992) |
| "To determine whether nitroglycerin is as effective as nifedipine in lowering the blood pressure in severe hypertension and hypertensive crisis, two groups of 20 patients received in random sequence either 1." | 9.07 | Comparison of nitroglycerin with nifedipine in patients with hypertensive crisis or severe hypertension. ( Bussmann, WD; Kenedi, P; Nast, HP; Rachor, N; von Mengden, HJ, 1992) |
| "In a double-blind, crossover trial 12 patients with hypertension and peripheral arterial disease were randomized to three months' treatment with captopril 25-50 mg twice daily or nifedipine SR 20-40 mg twice daily." | 9.07 | Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication. ( Breckenridge, A; Linge, K; McLoughlin, GA; Roberts, DH; Tsao, Y, 1992) |
| "The efficacy and safety of amlodipine in the long term treatment of outpatients with mild to moderate hypertension were examined in an open, non-comparative study." | 9.07 | [Effectiveness and tolerance of amlodipine in treatment of patients with mild to moderate hypertension. Results of a long-term study with a new calcium antagonist]. ( Ganzinger, U; Habeler, G; Lenzhofer, R; Pall, H; Tomaschek, A; Ziebart-Schroth, A; Zirm, B, 1992) |
| "Amlodipine, a novel dihydropyridine calcium-antagonist, was compared to slow-release nifedipine in a short-term study on 40 patients with mild to moderate essential hypertension, in order to assess the efficacy and tolerability of two different dihydropyridine calcium-antagonists with short and long half-life." | 9.07 | [A comparison between amlodipine and nifedipine retard in patients with essential arterial hypertension]. ( Bruzzone, F; Canale, C; Caponnetto, S; Lonati, A; Malvestiti, FM; Masperone, MA; Terrachini, V, 1992) |
| "The frequency and severity of adverse effects during the first 14 days of treatment with amlodipine (5 mg once daily), nifedipine retard (20 mg twice daily) or placebo were compared in a multicentre, three-way, cross-over study involving 97 patients with mild-to-moderate hypertension." | 9.07 | Comparison of early side effects with amlodipine and nifedipine retard in hypertension. ( Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH, 1992) |
| "Thirty-nine black patients with mild to moderate hypertension were treated for 1 year with various long-acting preparations of nifedipine, during which time serial changes in 24-hour ambulatory blood pressure (BP), exercise performance, left ventricular (LV) mass index and LV systolic function were evaluated." | 9.07 | Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension. ( Davis, J; Essop, MR; Middlemost, SJ; Sack, M; Sareli, P; Skoularigis, J; Wisenbaugh, T, 1992) |
| "The efficacy and safety of isradipine and nifedipine retard were compared in 51 patients with mild-to-moderate essential hypertension." | 9.07 | First clinical experience with isradipine in the treatment of hypertension in Portugal. ( Botelho, MA; Correia, JM; Mariano-Pego, G; Rocha-Gonçalves, F; Viegas, J, 1991) |
| "Carvedilol is a novel treatment for hypertension, having a balanced pharmacology of vasodilation and beta-receptor blockade." | 9.07 | A comparative study of carvedilol, slow-release nifedipine, and atenolol in the management of essential hypertension. ( Ball, SG; Dixon, S; Hall, S; Hallman, RJ; Harvey, RE; Prescott, RI, 1991) |
| "In 80 patients with moderate hypertension the effects of nisoldipine 10 mg b." | 9.07 | The effects of nisoldipine, diltiazem, nifedipine, and verapamil on hemodynamic parameters and red blood cells-platelet interactions in patients with arterial hypertension. ( Belousov, Y; Kushnaryov, V, 1991) |
| "The effects of the nifedipine gastrointestinal therapeutic system (GITS) on blood pressure (BP), systemic vascular resistance (SVR), and left ventricular (LV) performance were determined in eight patients with essential hypertension." | 9.07 | Nifedipine improves left ventricular function in patients with hypertension. ( Boucher, CA; Christensen, DM; Higgins, J; Zusman, RM, 1991) |
| "The aim of this study was to compare the antihypertensive efficacy and tolerability of lacidipine, a new dihydropyridine calcium antagonist, and slow-release nifedipine (SR) in patients with mild-to-moderate essential hypertension." | 9.07 | Comparative study of lacidipine and nifedipine SR in the treatment of hypertension: an Italian multicenter study. The Northern Italian Study Group of Lacidipine in Hypertension. ( Leonetti, G, 1991) |
| "Effect of sublingual nifedipine was evaluated in 39 cases of hypertensive emergencies (diastolic blood pressure greater than or equal to 120 mm Hg with impending organ failure, loss of vital function or death)." | 9.07 | Sublingual nifedipine in hypertensive emergencies with special reference to cerebrovascular accident. ( Gambhir, IS; Gupta, SS; Singh, DS, 1991) |
| "In 10 patients with moderate essential hypertension, the neurohumoral and hemodynamic effects of 4 days' treatment with 2 x 75 micrograms clonidine (C), 2 x 20 mg nifedipine retard (N), and a combination of the two (C/N) were studied and compared with baseline values." | 9.07 | [Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances]. ( Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension." | 9.07 | Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991) |
| "Sixteen patients with severe hypertension were treated for 1 year with extended release nifedipine, during which time serial changes in left ventricular mass index and associated alterations in left ventricular systolic function, left ventricular filling, plasma renin activity, atrial natriuretic peptide and catecholamines were evaluated." | 9.07 | Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991) |
| "Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension." | 9.07 | Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
| "Hemodynamic Effects of Isradipine and Nifedipine in Hypertension Myocardial wall tension is an important determinant of the oxygen demand, the function and the degree of hypertrophy of the left ventricle." | 9.07 | [The hemodynamic effects of isradipine and nifedipine in hypertension]. ( Burger, KJ; Distler, GA; Gross, P; Koppenhagen, K; Welzel, D; Wudel, E, 1991) |
| "Amlodipine (once daily) and captopril (twice daily) had comparable efficacy and safety in reducing the blood pressure of patients with mild and moderate essential hypertension." | 9.07 | A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results. ( Guevara, J; Hernández, O; Hernández, R; Urbina, A; Velasco, M, 1991) |
| "This study compared the efficacy and safety of 8 weeks of open treatment with the dihydropyridine calcium antagonists amlodipine and nitrendipine in mild-to-moderate hypertension." | 9.07 | Amlodipine compared to nitrendipine for the treatment of mild-to-moderate hypertension. ( Beressem, P; Englert, R; Kramar, M; Stafunsky, M; von Manteuffel, E, 1991) |
| "Twenty-one subjects with mild or moderate systemic hypertension were treated for 12 weeks with amlodipine, a new calcium antagonist of the dihydropyridine group." | 9.07 | Efficacy and tolerability of amlodipine in patients with mild-to-moderate hypertension. ( Meaney, E; Moguel, R; Olvera, R; Samaniego, V, 1991) |
| "The antihypertensive efficacy of amlodipine was studied in 22 patients (16 female, six male) with mild-to-moderate hypertension." | 9.07 | Clinical evaluation of amlodipine, a new long-acting calcium antagonist, in mild and moderate hypertension. ( Escudero, J; Hernandez, H, 1991) |
| "The effect of nifedipine on serum theophylline levels in 13 female hypertensive patients having asthma on theophylline therapy has been investigated." | 9.07 | Nifedipine alters serum theophylline levels in asthmatic patients with hypertension. ( Canberk, A; Eroğlu, L; Yilmaz, E, 1991) |
| "Forty-nine patients, with ages ranging from eighteen to seventy years and with mild to moderate primary hypertension (sitting diastolic blood pressure of greater than or equal to 95 mmgH and less than or equal to 115 mmHg) were randomized into a twenty-one-week, double-blind, prospective study to determine the effects of monotherapy of nifedipine GITS (gastrointestinal therapeutic system) versus atenolol on serum lipids, lipid subfractions, apolipoproteins, (apo), and blood pressure (BP)." | 9.07 | Effects of nifedipine GITS and atenolol monotherapy on serum lipids, blood pressure, heart rate, and weight in mild to moderate hypertension. ( Burger, MC; Houston, MC; Olafsson, L, 1991) |
| "Randomised study of diabetic patients with microalbuminuria treated with perindopril or nifedipine for 12 months and monitored for one or three months after stopping treatment depending on whether they were hypertensive or normotensive." | 9.07 | Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group. ( , 1991) |
| "Sublingual captopril (25 mg) was compared with sublingual nifedipine (10 mg) to determine their effectiveness and safety in the treatment of hypertensive emergencies." | 9.07 | Comparison of sublingual captopril and nifedipine in immediate treatment of hypertensive emergencies. A randomized, single-blind clinical trial. ( Angeli, P; Caregaro, L; Chiesa, M; Gatta, A; Merkel, C; Rondana, M; Sacerdoti, D, 1991) |
| "The effect of Hydergine/Nifedipine (Pontuc) on blood pressure in supine or exercise blood pressure as well as subjective well-being was evaluated in a randomized, double-blind interindividual comparison with Nifedipine in 50 elderly out-patients (34 females, 16 males) with mostly pretreated isolated systolic hypertension." | 9.07 | [Therapy comparison between the combination hydergine/nifedipine and nifedipine alone in patients with isolated systolic hypertension]. ( Dominiak, P; Weidinger, G, 1991) |
| "After screening a local population in the northern part of The Netherlands for hypertension, 125 patients (116 of whom had not previously used antihypertensive drugs) with a five times elevated diastolic pressure (DP) of between 95 and 130 mmHg were randomized and treated daily either with atenolol 50 mg o." | 9.07 | Captopril compared to atenolol in mild to moderate hypertension in a randomized double-blind controlled trial. ( Havinga, TK; May, JF; Schuurman, FH; ten Berge, BS; van der Veur, E; Wesseling, H, 1991) |
| "17 patients with isolated systolic hypertension (ISH) and 8 with diastolic hypertension (DH) were treated with 10 mg of nifedipine sublingually." | 9.07 | [Clinical effects of nifedipine on blood pressure and left ventricular performance in patients with isolated hypertension]. ( Hua, Q; Tang, Z; Wang, JR, 1991) |
| "Various aspects of carbohydrate and lipid metabolism have been studied in two groups of patients with mild hypertension before and after four months of treatment with either nifedipine (n = 12) or atenolol (n = 12)." | 9.07 | Comparison of the effects of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertension. ( Chen, YD; Hoffman, B; Reaven, GM; Sheu, WH; Swislocki, AL, 1991) |
| "The incidence and prevalence of cough related to enalapril was assessed by spontaneous reporting and a visual analogue scale during a 6 month random double-blind parallel-group study comparing enalapril with nifedipine." | 9.07 | Cough and enalapril: assessment by spontaneous reporting and visual analogue scale under double-blind conditions. ( Maclean, D; Ramsay, LE; Richardson, PJ; Yeo, WW, 1991) |
| "A study was undertaken to assess the use of intravenous nifedipine in controlling hypertension in patients following coronary artery surgery." | 9.06 | Intravenous nifedipine for control of hypertension in patients after coronary artery bypass graft surgery. ( Davis, ME; Feneck, RO; Jones, CJ; Walesby, RK, 1988) |
| "Forty outpatients (11 men and 29 women) aged between 65 and 85 years (mean age of 68 years) with mild to moderate hypertension [mean systolic/diastolic blood pressure (SBP/DBP) after 2 weeks on placebo of 175/102 mm Hg] were included in a randomized, double-blind, parallel-group study to compare the efficacy and tolerance of 10 mg of bisoprolol once daily (o." | 9.06 | Bisoprolol and nifedipine SR in the treatment of hypertension in the elderly. ( Carretero, J; Garcia, MJ; Garrido, M; Oliván Martinez, J; Pizarro, JL; Rodriguez Botaro, A, 1990) |
| "The long-term haemodynamic responses to amlodipine, a new long-acting calcium antagonist, were studied both at rest and during exercise in 18 patients (mean age 43 years) with essential hypertension." | 9.06 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1990) |
| "In patients with hypertension persisting on combined diuretic and beta-blocker therapy, the effects of an additional 9-week therapy with a calcium antagonist (nifedipine) versus a classical arterial vasodilator (hydralazine) were compared for changes in blood pressure (BP), plasma catecholamines (n = 15), and left ventricular (LV) systolic and diastolic function (n = 6)." | 9.06 | Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy. ( Burns, RJ; Frankel, D; Leenen, FH; Myers, MG, 1990) |
| "Nifedipine, in the gastrointestinal therapeutic system (GITS) formulation, a controlled-release formulation for once-a-day administration, was evaluated in the Modern Approach to the Treatment of Hypertension (MATH) trial." | 9.06 | Nifedipine gastrointestinal therapeutic system in the treatment of hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension (MATH) Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the therapeutic safety and efficacy of the once-a-day nifedipine gastrointestinal therapeutic system (GITS) formulation in a large and diverse cohort of patients with mild-to-moderate hypertension." | 9.06 | Antihypertensive effectiveness of nifedipine gastrointestinal therapeutic system in the elderly. The Modern Approach to the Treatment of Hypertension (MATH) Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| " The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the efficacy and safety of the new once-daily nifedipine gastrointestinal therapeutic system (GITS) formulation in a large cohort of mild-to-moderate hypertensive patients overall, and to identify specific effects of therapy in the presence of complicating factors such as diabetes and obesity." | 9.06 | Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "The effectiveness and safety of sustained action nifedipine (NF) were compared to those of chlorthalidone (CL) in two groups of 35 and 37 patients with mild to moderate hypertension followed up for 4 months." | 9.06 | [Comparison of chlorthalidone and sustained-action nifedipine in the treatment of mild to moderate arterial hypertension]. ( Calderón de la Barca Gázquez, JM; de Diego Cabrera, MS; González Santos, C; Iribarren Marín, MA; Martínez de la Iglesia, J; Pérula Torres, L, 1990) |
| "The arterial vasodilator properties of the dihydropyridine calcium antagonist amlodipine were compared with the effects of vascular muscle cyclic guanosine monophosphate production by sodium nitroprusside and with the effects of a combined infusion of amlodipine and the nondihydropyridine calcium antagonist verapamil in 8 untreated patients with primary hypertension." | 9.06 | Arterial vasodilator effects of the dihydropyridine calcium antagonist amlodipine alone and in combination with verapamil in systemic hypertension. ( Bühler, FR; Erne, P; Kiowski, W; Linder, L, 1990) |
| "The calcium antagonists of the dihydropyridine group, isradipine and nifedipine, were compared in 64 patients with mild to moderate hypertension (diastolic blood pressure 95 to 110mm Hg)." | 9.06 | The calcium antagonist isradipine in the therapy of hypertension. A double-blind crossover comparison with nifedipine. ( Burger, KJ; Welzel, D, 1990) |
| "The long acting angiotensin-converting enzyme inhibitor enalapril was compared with the calcium channel blocker nifedipine as sustained-release formulation in 136 patients with mild to moderate hypertension." | 9.06 | Comparative efficacy and safety of enalapril and sustained-release nifedipine in patients with mild to moderate hypertension. The Enalapril vs Nifedipine French Study Group. ( Artigou, JY; Benichou, M; Berland, J; Fressinaud, P; Grollier, G; Gueret, P; Nguyen, CD, 1990) |
| "In a double-blind, randomized, multicenter study of 194 patients with moderate hypertension, spironolactone and nifedipine were found to reduce blood pressure (BP) to about the same extent and in the same percentage of patients after 45 days of treatment (47 and 50%, respectively)." | 9.06 | Spironolactone versus nifedipine in essential hypertension. ( Capron, MH; Henry, M; Pelletier, B; Wehrlen, M, 1990) |
| "The aim of the study was (1) to determine the difference in aortic input impedance and derived parameters between hypertensives and normotensives; and (2) to assess the acute effects of nifedipine on the aortic impedance, compliance, and resistance in patients with hypertension." | 9.06 | Effects of nifedipine on systemic hydraulic vascular load in patients with hypertension. ( Chang, KC; Chen, HI; Hsieh, KS; Kuo, TS, 1990) |
| "This randomised, parallel group study was designed to compare the efficacy of nifedipine (40 mg once daily) combined with either the dopamine agonist, co-dergocrine mesilate (4 mg once daily) or the diuretic mefruside (25 mg once daily) in 40 patients with essential arterial hypertension and a diastolic blood pressure greater than 105 mmHg." | 9.06 | Influence of co-dergocrine mesilate/nifedipine compared to mefruside/nifedipine on circadian blood pressure in patients with essential hypertension. ( Heintz, B; Heller, A; Kirsten, R; Nelson, K, 1990) |
| "Antihypertensive effects of labetalol and nifedipine were evaluated in a double blind cross over trial in ambulatory patients with moderately severe hypertension (mean diastolic BP 101." | 9.06 | Labetalol and nifedipine in the management of essential hypertension. ( Prasad, NK, 1990) |
| "Forty-one elderly patients with mild to moderate hypertension (resting diastolic blood pressure 100-130 mmHg after an eight week placebo run-in phase) were randomised to a double-blind parallel group comparison of nifedipine retard 10 mg twice daily or atenolol 50 mg once daily." | 9.06 | Comparative trial of nifedipine retard and atenolol in the treatment of elderly patients with mild to moderate hypertension. ( Clamp, M; Holmes, B; Wilcox, R, 1990) |
| "We assessed the efficacy of long-acting nifedipine as monotherapy in 52 patients with mild to moderate essential hypertension in a randomized, controlled crossover study." | 9.06 | Long-acting nifedipine versus metoprolol as monotherapy for essential hypertension. A randomized, controlled crossover study. ( Pun, CO; Woo, KS, 1990) |
| "A total of 136 patients with mild to severe uncomplicated essential hypertension were evaluated in a multicenter, randomized, double-blind, double-placebo, parallel study to compare the effect of lisinopril, a new angiotensin-converting enzyme inhibitor, with that of nifedipine." | 9.06 | Comparative trial of lisinopril and nifedipine in mild to severe essential hypertension. ( Baglivo, H; Boeijinga, JK; Breckenridge, AM; Clement, D; Johnston, GD; Klein, W; Kramer, R; Luccioni, R; Meurer, KA; Mörlin, C, 1987) |
| " The effects of intraarterially infused nifedipine, reactive hyperemia after 10 min arterial occlusion combined with handgrip exercise and local heating, and arterial occlusion combined with nifedipine on forearm blood flow and blood pressure were investigated in random order." | 9.06 | Effects of reactive hyperemia and nifedipine on forearm vascular resistance in essential hypertension: evidence for functional abnormality. ( Braun, J; Distler, A; Gotzen, R; Meyer-Sabellek, W; Schulte, KL, 1987) |
| "The effects of two antihypertensive agents, nifedipine (N) and captopril (C), on left ventricular (LV) mass and volume were studied in 16 patients with essential hypertension (8 treated with N and 8 with C for 6 months) by means of a complete M-mode echocardiogram monitored by two-dimensional echocardiography." | 9.06 | Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril. ( Accardi, R; Arcaro, G; Covi, G; Lechi, A; Sheiban, I; Zenorini, C, 1987) |
| "Lisinopril, a long-acting angiotensin converting enzyme inhibitor, and the calcium channel blocker nifedipine in its retard formulation, were compared as monotherapy in a group of 45 patients with essential hypertension." | 9.06 | Comparative efficacy of lisinopril and nifedipine retard in essential hypertension: a double-blind, placebo-controlled trial. ( Breckenridge, AM; Grimmer, SF; Johnston, GD; Kondowe, G; Meany, TB; Richardson, PJ, 1987) |
| "Once-daily administration of amlodipine, a long-acting dihydropyridine calcium-channel blocker, and atenolol, a cardioselective beta-adrenoceptor blocking agent, were compared in patients with mild to moderate hypertension in a multicenter placebo-controlled trial." | 9.06 | Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension. ( Cocco, G; de Bruijn, B; Tyler, HM, 1988) |
| "Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with placebo and atenolol in 125 patients with mild to moderate systemic hypertension [supine diastolic blood pressure (DBP) 90-114 mm Hg]." | 9.06 | A randomized placebo-controlled comparison of amlodipine and atenolol in mild to moderate systemic hypertension. ( Brobyn, R; Brown, RD; Frishman, WH; Johnson, BF; Reeves, RL; Wombolt, DG, 1988) |
| "The antihypertensive efficacy of once-daily amlodipine was studied in a group of 30 patients with mild to moderate hypertension in a double-blind, placebo-controlled, parallel-group study." | 9.06 | Once-daily amlodipine in the treatment of mild to moderate hypertension. ( Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Webster, J, 1988) |
| "A multicenter, placebo-controlled trial assessed the antihypertensive efficacy and safety of different doses of amlodipine in patients with mild to moderate hypertension." | 9.06 | Amlodipine: a double-blind evaluation of the dose-response relationship in mild to moderate hypertension. ( Frick, MH; McGibney, D; Tyler, HM, 1988) |
| "Amlodipine 10 mg once daily added to captopril 25 mg twice daily for 4 weeks in patients with moderate to severe hypertension significantly improved blood pressure control (by -18/-12 and -20/-12 mm Hg for supine and standing systolic/diastolic pressures respectively, p less than 0." | 9.06 | A double-blind crossover comparison of amlodipine and placebo added to captopril in moderate to severe hypertension. ( Maclean, D; Mitchell, ET; Tyler, HM; Walker, P; Wilcox, RG, 1988) |
| "One hundred sixty patients with mild to moderate essential hypertension entered this double-blind parallel group comparison of amlodipine, verapamil, and placebo." | 9.06 | Comparison of amlodipine and verapamil in the treatment of mild to moderate hypertension. ( Lorimer, AR; Smedsrud, T; Tyler, HM; Walker, P, 1988) |
| "Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with hydrochlorothiazie (HCTZ) in 145 patients with mild to moderate hypertension." | 9.06 | Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension. ( Ames, RP; Applegate, WB; Burris, JF; Davidov, ME; Mroczek, WJ; Ram, CV, 1988) |
| "In an acute, double-blind, crossover study on 12 patients with essential hypertension, the interaction between nifedipine and prazosin was investigated in the supine position." | 9.06 | Nifedipine-prazosin interaction in patients with essential hypertension. ( Farsang, C; Kiss, I, 1989) |
| "The antihypertensive efficacy and suitability for once daily dosing of amlodipine, a new calcium antagonist, was studied in a series of 205 patients with mild to moderate hypertension." | 9.06 | A dose-response study of amlodipine in mild to moderate hypertension. ( Frick, MH; McGibney, D; Tyler, HM, 1989) |
| "This is a double blind parallel group comparison in patients with mild-moderate hypertension, of amlodipine, verapamil and placebo." | 9.06 | A comparison of amlodipine, verapamil and placebo in the treatment of mild to moderate hypertension. Amlodipine Study Group. ( Lorimer, AR; Smedsrud, T; Tyler, HM; Walker, P, 1989) |
| "The antihypertensive effects of lisinopril 20 mg once daily and slow-release nifedipine 20 mg twice daily were compared in a double-blind, parallel group, 10-week study involving 274 patients with mild to moderate hypertension." | 9.06 | Lisinopril versus slow-release nifedipine in the treatment of mild to moderate hypertension: a multicentre study. The Cooperative Study Group. ( Serradimigni, A; Witchitz, S, 1989) |
| " In order to examine whether nitrendipine was superior to slow release nifedipine as monotherapy in the treatment of mild to moderate essential hypertension, the two agents were administered to 22 patients in a double-blind randomized cross-over study, incorporating low and titrated dose regimes." | 9.06 | A double-blind randomized cross-over study of the efficacy and tolerability of nifedipine and nitrendipine in the treatment of mild to moderate hypertension. ( Heagerty, AM; Swales, JD, 1989) |
| "The antihypertensive effects of nisoldipine, a calcium channel blocker, and atenolol, a beta-adrenergic blocker, were compared in patients with mild or moderate essential hypertension." | 9.06 | Comparison of nisoldipine and atenolol in the treatment of essential hypertension. ( Fukuyama, M; Okabayashi, H; Takahashi, H; Yoneda, S; Yoshimura, M, 1989) |
| "The relationship between the age and the clinical efficacy of a new long acting calcium entry blocker, nisoldipine, was investigated in essential hypertension using two double blind group studies, in which nifedipine or atenolol was used as a control drug." | 9.06 | [Age and efficacy of new long acting calcium blocker, nisoldipine, is essential hypertension]. ( Kaneko, Y; Kuwajima, I; Takeda, T, 1989) |
| "This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone." | 9.06 | Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989) |
| "We studied the incidence of oedema 2 weeks following initiation of nifedipine therapy for hypertension in a group of 10 diabetic subjects, and also measured skin blood flow (SBF) with a laser Doppler flowmeter, before and after lowering the foot." | 9.06 | Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients. ( Rayman, G; Tooke, JE; Williams, SA, 1989) |
| "The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy." | 9.06 | Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989) |
| " Preliminary experience suggests that the gastrointestinal therapeutic system (GITS) push-pull osmotic pump formulation of nifedipine is safe and efficacious in the treatment of hypertension." | 9.06 | The nifedipine gastrointestinal therapeutic system in the treatment of hypertension. ( Frishman, WH; Garofalo, JL; Greenberg, SM; Rothschild, A; Rothschild, M; Soberman, J, 1989) |
| "The antihypertensive efficacy and tolerability of lisinopril, a new long acting angiotensin converting enzyme inhibitor, and nifedipine, in a retard formulation, were compared in a randomized six month double-blind study, in 45 patients with essential hypertension." | 9.06 | Lisinopril in essential hypertension: a six month comparative study with nifedipine. ( Breckenridge, AM; Grimmer, SF; Johnston, GD; Kondowe, G; Meany, B; Richardson, PJ, 1987) |
| "Sixteen patients with mild to moderate essential hypertension were randomly allocated to 6 weeks of treatment with nifedipine and captopril in a crossover trial." | 9.06 | The effect of nifedipine and captopril on platelet activation and prostanoid production in essential hypertension. ( Birkebaek, NH; Jakobsen, P; Vejby-Christensen, H; Winther, K, 1988) |
| "A randomised double blind parallel group study was performed to compare the efficacy and acceptability of slow release nifedipine (maximum dose 40 mg twice a day) with those of atenolol (maximum dose 100 mg once a day) as single agents for the treatment of essential hypertension." | 9.06 | Nifedipine and atenolol singly and combined for treatment of essential hypertension: comparative multicentre study in general practice in the United Kingdom. Nifedipine-Atenolol Study Review Committee. ( , 1988) |
| "The haemodynamic impact of alpha- and beta-adrenoceptor blockade (labetalol) was compared with that of slow-calcium channel blockade (nifedipine) in 32 patients with sustained elevation of systemic arterial pressure (systolic blood pressure greater than 160; diastolic blood pressure greater than 95 mmHg) following a recent myocardial infarction (6-22 h)." | 9.06 | Sympathetic (alpha-beta) or calcium channel blockade for hypertensive myocardial infarction? A haemodynamic comparison of labetalol and nifedipine. ( Hussain, M; Nelson, GI; Reynolds, GW; Richmond, A; Silke, B; Taylor, SH; Verma, SP; Wilson, JA, 1988) |
| "Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study." | 9.06 | Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989) |
| "Long-acting nifedipine and nitrendipine, a nifedipine analogue, have been proposed for single-drug therapy of hypertension." | 9.06 | Nitrendipine vs. long-acting nifedipine in mild, moderate and severe hypertension. ( De Cesare, N; Galli, C; Guazzi, MD; Salvioni, A; Tamborini, G, 1986) |
| " The antihypertensive efficacy of once-daily amlodipine was studied in a group of 30 patients with mild to moderate hypertension in a double-blind, placebo controlled parallel group study." | 9.06 | Once daily amlodipine in the treatment of mild to moderate hypertension. ( Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Towler, HM; Webster, J, 1987) |
| "The two dihydropyridine calcium antagonists, nicardipine and nifedipine, were compared in 12 patients with both stable angina pectoris and systemic hypertension using a double-blind, crossover protocol." | 9.06 | A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension. ( Bonandi, L; Dei Cas, L; Feroldi, P; Metra, M; Nodari, S; Nordio, G; Raddino, R; Visioli, O, 1988) |
| "The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women." | 9.06 | The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988) |
| "In this randomised, double-blind, crossover trial, the efficacy in hypertension of atenolol and nifedipine as single agents or in combination was compared." | 9.06 | Atenolol and sustained release nifedipine alone and in combination in hypertension. A randomised, double-blind, crossover study. ( Anderton, JL; Crowe, PF; Mittra, B; Perks, WH; Stanley, NN; Vallance, BD, 1988) |
| "This randomised, double-blind, crossover study investigated the haemodynamic effects of a beta-blocker (atenolol 50mg) and a calcium antagonist (sustained release nifedipine 20mg) given either separately or in combination in 3 groups of patients with mild to moderate essential hypertension." | 9.06 | Efficacy and tolerability of atenolol, nifedipine and their combination in the management of hypertension. ( Heath, ID; Larkin, H; Stanley, NN; Thirkettle, JL; Varma, MP, 1988) |
| "The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension." | 9.06 | Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 9.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "Twenty-nine subjects with mild to moderate essential hypertension completed this 13 week randomized, double-blind, placebo-controlled study comparing the antihypertensive effects of nifedipine GITS (N) (30-60 mg/day), hydrochlorothiazide (H) (25-50 mg/day) and placebo (P)." | 9.06 | Nifedipine GITS and hydrochlorothiazide in essential hypertension. ( Callender, K; Halperin, AK; Hashimoto, F; Jueng, C, 1987) |
| "The efficacy and safety of nifedipine in a gastrointestinal therapeutic system (GITS) push-pull osmotic pump formulation was compared with long-acting propranolol in 49 patients with mild to moderate hypertension already receiving diuretics." | 9.06 | Multicenter comparison of the nifedipine gastrointestinal therapeutic system and long-acting propranolol in patients with mild to moderate systemic hypertension receiving diuretics. A preliminary experience. ( Frishman, WH; Garofalo, JL; Greenberg, SM; Rothschild, A; Rothschild, M; Soberman, J, 1987) |
| "In a randomised, crossover study of patients with moderate to severe essential hypertension, the effects of the calcium entry antagonist nifedipine and the beta-receptor blocking drug acebutolol were studied on their own, and in combination." | 9.06 | Nifedipine and acebutolol in combination for the treatment of moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 9.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "In a series of controlled studies for periods of 4 to 6 weeks comprising 103 patients altogether, and in 1 long-term trial for 1 year, various dosages of instant and sustained-release verapamil were administered in the treatment of mild and moderate essential hypertension." | 9.06 | Instant and sustained-release verapamil in the treatment of essential hypertension. ( Hals, O; Lauve, O; Midtbø, K; Storstein, L; van der Meer, J, 1986) |
| "Three therapies were used to treat 35 patients with mild to moderate systemic hypertension: (1) the cardioselective beta-adrenoceptor blocker atenolol, (2) the calcium antagonist nifedipine and (3) combination therapy for those who failed to reach the target diastolic blood pressure (BP) of less than 90 mm Hg with monotherapy." | 9.06 | Atenolol plus nifedipine for mild to moderate systemic hypertension after fixed doses of either agent alone. ( Daniels, AR; Opie, LH, 1986) |
| "In a double-blind cross-over study, the effect on blood pressure (BP), heart rate (HR) and plasma noradrenaline concentration (pNA) of placebo or felodipine given in addition to hydrochlorothiazide was studied in 12 male patients with essential hypertension, not satisfactorily controlled with the diuretic alone." | 9.06 | Treatment of essential hypertension with felodipine in combination with a diuretic. ( Elmfeldt, D; Hedner, T; Samuelsson, O; Sjögren, E, 1986) |
| "We randomized patients with severe hypertension in the Medical Intensive Care Unit to a treatment regimen of oral nifedipine or intravenous nitroprusside." | 9.06 | A randomized comparison of nifedipine and sodium nitroprusside in severe hypertension. ( Franklin, C; Mamdani, B; Nightingale, S, 1986) |
| "Twelve patients with essential hypertension on no other drug treatment were entered into a randomised crossover study of 5, 10 and 20 mg capsules of nifedipine given 3 times a day and 20 mg tablets given twice a day." | 9.06 | Dose response and length of action of nifedipine capsules and tablets in patients with essential hypertension: a randomised crossover study. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Tucker, FA, 1986) |
| "The effectiveness of nifedipine as first-line monotherapy for mild diastolic hypertension (range: 95 to 105 mm Hg) was tested in this placebo-controlled, double-blind, randomized trial." | 9.06 | Monotherapy of mild hypertension with nifedipine. ( Corkadel, LK; Fan, F; Horwitz, LD; Pacheco, JP; Reeves, RL; Wright, RA, 1986) |
| "We studied the renal effects of nicardipine, a calcium entry blocker, in seven patients with mild-to-moderate essential hypertension." | 9.06 | Renal effects of nicardipine in patients with mild-to-moderate essential hypertension. ( Baba, T; Boku, A; Ishizaki, T; Sone, K; Takebe, K, 1986) |
| "Fifty-one patients with essential hypertension, 22 males and 29 females with a mean age of 51 (range, 28 to 65 years), were studied for more than 12 months in a controlled clinical trial with nitrendipine, a new calcium antagonist agent." | 9.05 | Clinical experience with long-term nitrendipine treatment in essential hypertension. ( Lasaridis, A; Settas, L; Tourkantonis, A, 1984) |
| "Patients with mild to moderate essential hypertension were treated in four centers with hydrochlorothiazide (HCTZ) 25 mg daily for 4 weeks." | 9.05 | Comparison of nitrendipine combined with low-dose hydrochlorothiazide to hydrochlorothiazide alone in mild to moderate essential hypertension. ( Glasser, SP; Leibowitz, DA; McMahon, SG; Ram, CV; Schoenberger, JA; Vanov, SK, 1984) |
| "The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension." | 9.05 | Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982) |
| "In a double-blind, cross-over study for 6 weeks that included 28 patients with essential hypertension, WHO stage I-II, the hypotensive action of verapamil (160 mg thrice daily) was compared with nifedipine (20 mg slow release twice daily)." | 9.05 | Verapamil compared with nifedipine in the treatment of essential hypertension. ( Hals, O; Midtbø, K; van der Meer, J, 1982) |
| "The antihypertensive effect of 20 mg of nitrendipine (BAY e 5009) was compared with that of 40 mg, administered orally once daily to 12 patients with essential hypertension (WHO I-II)." | 9.05 | Experience with nitrendipine--a new calcium antagonist--in hypertension. ( Andrén, L; Hansson, L; Orö, L; Ryman, T, 1982) |
| "Nifedipine (10 mg qid) and captopril (25 mg qid) were tested alone and in combination in 14 patients suffering from severe primary hypertension." | 9.05 | Calcium-channel blockade with nifedipine and angiotensin converting-enzyme inhibition with captopril in the therapy of patients with severe primary hypertension. ( Bartorelli, A; De Cesare, N; Galli, C; Guazzi, MD; Salvioni, A; Tamborini, G; Tramontana, C, 1984) |
| "In a multi-center study, nifedipine (Bay a 1040, Adalat) (10 mg capsule) was administered, in liquid form and via sublingual route, to 22 cases who were diagnosed to have clinically severe systolic hypertension, and the depressor effect of the treatment was studied over a period of 4 h." | 9.05 | Acute antihypertensive effect of nifedipine by sublingual route in cases with clinically severe systolic hypertension. A study up to 4 h after administration. ( Arakawa, M; Fueki, T; Fukuda, T; Hirakawa, S; Ito, H; Kondo, Y; Mori, N; Shibasaki, T; Watanabe, I; Yasue, T, 1984) |
| "The antihypertensive efficacy and the acceptability of nifedipine (NI, Adalat) and the usefulness of its combination with a beta 1-selective blocking drug, acebutolol (AC), were studied in a placebo controlled trial on 15 patients with moderate hypertension." | 9.05 | Acebutolol and nifedipine in the treatment of arterial hypertension: efficacy and acceptability. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Liguori, V; Petitto, M; Santomauro, M; Villari, B, 1984) |
| "The efficacy of nifedipine in the treatment of hypertension was assessed in 15 patients whose hypertension continued while being treated with atenolol 100 mg and bendrofluazide 5 mg daily." | 9.05 | Role of nifedipine in treatment of hypertension. ( Dollery, CT; Murphy, MB; Scriven, AJ, 1983) |
| "We compared the efficacy and safety of nitrendipine with that of hydralazine in 21 subjects with essential hypertension." | 9.05 | Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension. ( Aguila, E; Baz, R; Lopez, LM; Mehta, JL, 1984) |
| " A survey of 122 patients with resistant hypertension treated long-term with nifedipine and a control group of 102 similar patients treated with hydralazine revealed that nifedipine at an average dose of 40 mg daily caused a fall in blood pressure similar to that achieved with hydralazine in a dose of 86 mg daily." | 9.05 | Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients. ( Bulpitt, CJ; Dollery, CT; Murphy, MB, 1984) |
| "1 The effect of oral nifedipine has been examined in patients with hypertension in whom arterial pressure was not adequately controlled by the combination of a beta-adrenoceptor antagonist (or alpha-methyldopa) and a diuretic." | 9.05 | Nifedipine in the treatment of hypertension: report of a double-blind controlled trial. ( Bayley, S; Dobbs, RJ; Robinson, BF, 1982) |
| "The acute effects of oral administration of niludipine (Bay a 7168), a new dihydropyridine derivative Ca2+-antagonist, on blood pressure (BP), hemodynamics and plasma renin activity (PRA) were investigated in patients with essential hypertension (n = 28) and normotensive volunteers (n = 7)." | 9.05 | Acute hypotensive, hemodynamic effects of long-term treatment with niludipine, a Ca2+-antagonist, in patients with essential hypertension. Niludipine monotherapy and combination with a beta-blocker and a diuretic). ( Aoki, K; Sato, K, 1982) |
| "The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension." | 9.05 | Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980) |
| "In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W." | 9.05 | Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981) |
| "In a double-blind trial 26 patients with essential hypertension were treated with nifedipine or placebo for 8 weeks, following a 4-week run-in-placebo period in all patients." | 9.05 | Effects of treatment with nifedipine and metoprolol in essential hypertension. ( Eggertsen, R; Hansson, L, 1982) |
| "Thirty patients with moderate to severe hypertension (diastolic blood pressure greater than or equal to 115 mmHg), after a run-in wash out period of 15 days, were treated with muzolimine at a dosage of 20 mg once daily, given at 1 p." | 9.05 | Muzolimine and nitrendipine in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Iacono, C; Petitto, M, 1985) |
| "The effectiveness and tolerability of nitrendipine (Bay e 5009) and atenolol in the treatment of mild or moderate arterial hypertension in monotherapy and in association were evaluated in a randomized double-blind study." | 9.05 | Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Petitto, M; Santomauro, M; Villari, B, 1985) |
| "The aim of this study was to compare the new vasodilator felodipine with nifedipine in 18 patients with poorly controlled hypertension." | 9.05 | Comparative trial of felodipine and nifedipine in refractory hypertension. ( Aberg, H; Lindsjö, M; Mörlin, B, 1985) |
| "116 patients from 4 clinics participated in a double blind study to assess the efficacy of (BAY l 5240), a nifedipine-acebutolol fixed combination (10 mg + 100 mg), as compared to nifedipine 20 mg in essential hypertension." | 9.05 | Effects of BAY l 5240, a fixed combination of low dose nifedipine and acebutolol on hypertension: comparison with standard dose nifedipine. ( Gfrerer, G; Gunselmann, W; Hennies, L; Hess, K; Lejeune, P; Rittgerodt, K; Schreiber, U; Winn, K, 1985) |
| "Fifty patients with mild essential (primary) hypertension entered a double-blind, parallel-group study with either nicardipine 30 mg three times daily or placebo, randomly assigned as monotherapy for 6 weeks." | 9.05 | Nicardipine hydrochloride in essential hypertension--a controlled study. ( Asplund, J, 1985) |
| "The dose-response effects of oral nicardipine on the systemic blood pressure were examined in 54 patients with uncomplicated essential hypertension (DBP greater than or equal to 100 mm Hg)." | 9.05 | Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension. ( Frais, MA; Jackson, N; Lee, P; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "In a randomised, double-blind, cross over trial, 25 patients with mild to moderate primary hypertension were given nifedipine 20-40 mg twice daily and labetalol 200-400 mg twice daily after a 4 week period on placebo, followed by the two drugs in combination." | 9.05 | Antihypertensive and metabolic effects of nifedipine and labetalol alone and in combination in primary hypertension. ( Karlberg, BE; Ohman, KP; von Schenck, H; Weiner, L, 1985) |
| "114 patients from four clinics participated in a double blind study designed to assess the efficacy of a nifedipine-acebutolol fixed combination -10 mg + 100 mg - as compared with acebutolol -200 mg- in essential hypertension." | 9.05 | Effects of a fixed combination of low dose nifedipine and acebutolol on essential hypertension: comparison with standard dose acebutolol. ( Gfrerer, G; Gunselmann, W; Hoppe, I; Lejeune, P; Mummel, P; Petersen, B; Schreiber, U; Winkler, E, 1985) |
| "In a randomized, double-blind, placebo-controlled crossover trial, diltiazem and nifedipine were compared in 10 patients with stable angina pectoris and mild to moderate hypertension (supine diastolic blood pressure greater than or equal to 90 mm Hg)." | 9.05 | Comparison of diltiazem and nifedipine for both angina pectoris and systemic hypertension. ( Allen, L; Charlap, S; Dorsa, F; Frishman, WH; Goldberger, J; Kimmel, B; Stroh, J; Strom, J, 1985) |
| "A controlled multicentre trial was organised to compare the effects of 20 mg Nifedipine tablets (N) and 2,5 mg Indapamide tablets (I) during a 4 months' treatment period after a placebo period, in 59 patients with moderate essential hypertension (n = 59)." | 9.05 | [Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension]. ( Aubert, P; Chaignon, M; Guédon, J; Lucsko, M; Rapoud, JP, 1985) |
| "Ambulatory monitoring of BP was performed in 11 patients whose 6 suffering from systo-diastolic (group 1) and 5 from systolic hypertension only (group 2) by Pressurometer III Del Mar Avionics after placebo (P), slow release Nifedipine (srN) 20 mg b." | 9.05 | Ambulatory BP monitoring after acute administration of slow release nifedipine, alone or in combination with acebutolol, in systo-diastolic and in systolic hypertension. ( Giannola, A; Immordino, R; Indovina, G; Novo, S; Raineri, A; Strano, A, 1985) |
| "The effects of slow-release nifedipine on blood pressure and cardiac workload have been studied during bicycle exercise testing in a randomized, double blind trial in 20 patients with mild to moderate hypertension." | 9.05 | Slow-release nifedipine versus placebo in the treatment of arterial hypertension. A double blind ergometric evaluation of cardiac workload. ( de Simone, G; di Lorenzo, L; Fasano, ML; Ferrara, LA; Lauria, R, 1985) |
| "The efficacy and safety of a new slow-release formulation of nifedipine ("Adalat Retard") were assessed in a double-blind cross-over trial in 19 subjects with essential hypertension (14 male, 5 female--ages: 34-72 years), 14 of whom continued previous antihypertensive medication." | 9.05 | Slow-release nifedipine as a single or additional agent in the treatment of essential hypertension--a placebo-controlled crossover study. ( Bune, AJ; Chalmers, JP; West, MJ; Wing, LM, 1985) |
| "Short-acting nifedipine has been abandoned as a treatment for severe hypertension in adults as a result of significant adverse effects." | 8.82 | Safety of short-acting nifedipine in children with severe hypertension. ( Flynn, JT, 2003) |
| "Nifedipine administration for hypertensive emergencies can induce neurological and cardiac events due to abrupt hypotension." | 8.80 | Hypotension and coronary events on nifedipine: reassessing nifedipine safety. ( , 1998) |
| "Nifedipine, as most calcium-antagonist drugs, is widely used for the treatment of angina pectoris and primary hypertension." | 8.80 | [Edema and skin ulcers of the lower limbs as a collateral effect of nifedipine. A clinical case report]. ( Luca, S; Romeo, S, 1999) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 8.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| "META-ANALYSIS: A meta-analysis of published randomized control trials of nifedipine in hypertension and stable angina pectoris was performed." | 8.79 | Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension. ( Caubet, JF; Chalmers, TC; Cory, D; Kupelnick, B; Ross, SD; Schmid, CH; Stason, W; Whiting, G, 1996) |
| "Nifedipine and atenolol are first choice drugs in the treatment of arterial hypertension and angina pectoris." | 8.78 | [Pharmacology and clinical use of a fixed combination of nifedipine and slow release atenolol (Niften) in the treatment of arterial hypertension and angina pectoris]. ( Verdecchia, P, 1993) |
| "Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris." | 8.78 | Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991) |
| "The calcium channel blocker nifedipine is an effective antihypertensive agent for the treatment of severe hypertension and hypertensive crises." | 8.77 | Treatment of severe hypertension and hypertensive crises with nifedipine. ( Houston, MC, 1987) |
| "The calcium channel blocker, nifedipine, is an effective antihypertensive agent for the treatment of hypertensive urgencies and emergencies." | 8.77 | Treatment of hypertensive urgencies and emergencies with nifedipine. ( Houston, MC, 1986) |
| "Nifedipine is one of the common calcium channel blockers (CCBs) for hypertension that induce peroxisome-proliferator-activated receptor γ coactivator 1-α, which is envisioned as a potential therapeutic target in bone disease." | 8.31 | Association between clinical use of nifedipine and the risk of osteoporosis: a nationwide retrospective cohort study. ( Chang, CM; Chen, YC; Chou, YC; Lin, MH; Lin, TK; Sun, CA; Wu, WT, 2023) |
| "This study aimed to evaluate the efficacy of nifedipine controlled-release tablets combined with sacubitril valsartan in diabetic nephropathy (DN) patients with hypertension." | 8.31 | Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension. ( Hu, L; Liu, G; Wei, Y, 2023) |
| "This retrospective multi-institutional database analysis aimed to evaluate the blood-pressure-lowering efficacy and clinical outcomes of a generic versus brand-name nifedipine for hypertension management." | 8.12 | Comparative effectiveness of generic nifedipine versus Adalat long-acting nifedipine for hypertension treatment: A multi-institutional cohort study. ( Chen, WJ; Chu, PH; Chu, YC; Ho, CT; Hsiao, FC; Lin, CP; Tung, YC; Tzyy-Jer, H, 2022) |
| "To assess whether readmission for hypertension by 6 weeks postpartum differed between patients discharged on nifedipine or labetalol." | 8.12 | Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine. ( Do, SC; Druzin, ML; El-Sayed, YY; Girsen, AI; Herrero, T; Kan, P; Leonard, SA; Lyell, DJ; Panelli, DM, 2022) |
| "In a prospective, multicenter, observational study, Chinese patients with CKD and uncontrolled hypertension were given nifedipine GITS 60 mg with a primary endpoint of change in office systolic BP (SBP) at 12 weeks." | 8.02 | Effectiveness and Tolerability of Nifedipine GITS in Patients with Chronic Kidney Disease and Uncontrolled Hypertension: A Prospective, Multicenter, Observational Study (ADRENAL). ( Chen, J; Chen, Q; Cheng, H; Hong, F; Huang, J; Li, R; Li, W; Liu, C; Liu, J; Lv, R; Shen, S; Song, W; Wang, H; Wang, J; Wei, L; Wu, H; Xiao, H; Yu, F; Zhang, T; Zhang, X, 2021) |
| " This nationwide retrospective database analysis aimed to evaluate the efficacy and safety of a generic versus brand-name nifedipine for hypertension treatment." | 7.96 | Efficacy and safety outcomes of one generic nifedipine versus ADALAT long-acting nifedipine for hypertension management. ( Chen, WJ; Chu, PH; Chu, YC; Hsiao, FC; Hsu, TJ; Lin, CP; Tung, YC, 2020) |
| " Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury." | 7.85 | Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017) |
| " It was concluded that the formulated nifedipine pulsatile dosage form could be useful in the treatment of hypertension." | 7.85 | Development and Characterization Pulsatile Microspheres of Nifedipine for Hypertension. ( Gupta, GD; Taneja, R, 2017) |
| "To measure the plasma concentrations of adrenomedullin (ADM),atrial natriuretic peptide (ANP), and brain natriuretic peptide (BNP), and investigate their pathophysiological functions in patients with primary aldosteronism (PA)." | 7.81 | Pathophysiological functions of adrenomedullin and natriuretic peptides in patients with primary aldosteronism. ( Hu, W; Wang, W; Xu, CG; Zhang, XB; Zhou, PH, 2015) |
| " Using this unique model we investigated effects on AAA formation of the L-type calcium channel blocker nifedipine, in view of the unclear relationship between hypertension and AAA, and unclear mechanisms of aneurysm protective effects of some blood pressure lowering drugs." | 7.81 | Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications. ( Cai, H; Miao, XN; Siu, KL, 2015) |
| "In this case report, we describe the clinical course over a 14-year follow-up in a 47-year-old diabetes patient with severe chronic periodontitis and nifedipine-induced gingival overgrowth." | 7.78 | Clinical case report of long-term follow-up in type-2 diabetes patient with severe chronic periodontitis and nifedipine-induced gingival overgrowth. ( Fujinami, K; Shibukawa, Y; Yamashita, S, 2012) |
| "To describe the case of treatment with amlodipine in a poorly controlled hypertension in a pediatric patient diagnosed with tricodistrofia." | 7.78 | Amlodipine in pediatric patient with uncontrolled multifactorial hypertension. Formulation of amlodipine oral suspension. ( Arias Santos, I; Lago Rivero, N; Paradela Carreiro, A, 2012) |
| "To compare the clinical efficacy and safety of sublingual nifedipine and intravenous urapidil in the treatment of acute postoperative hypertension." | 7.77 | [Efficacy of sublingual nifedipine and intravenous urapidil for treatment of acute postoperative hypertension]. ( Lou, N; Wang, DF; Wang, Z, 2011) |
| "To determine the effect of combination of edible oils on blood pressure, anthropometric parameters, lipid profile, lipid peroxidative markers, antioxidant status and electrolytes in drug (nifedipine) taking patients with hypertension." | 7.77 | Effect of combination of edible oils on blood pressure, lipid profile, lipid peroxidative markers, antioxidant status, and electrolytes in patients with hypertension on nifedipine treatment. ( Al-Numair, KS; Chandramohan, G; Kalaiarasi, P; Pugalendi, KV; Rao, RK; Sudhakar, B, 2011) |
| "Drug-induced gingival overgrowth (DIGO) is a significant problem for periodontologists and this side effect is frequently associated with three particular drugs: phenytoin, cyclosporin A and nifedipine." | 7.76 | Non-surgical treatment of gingival overgrowth induced by nifedipine: a case report on an elderly patient. ( Cabral, PA; Cimões, R; de Carvalho Farias, B; Gusmão, ES; Jamelli, SR, 2010) |
| "A 54-year-old woman started to take nifedipine orally for hypertension on February 18, 2006." | 7.75 | [A case of Sjögren syndrome with nifedipine-induced pneumonia]. ( Chida, E; Nagashima, H; Ogawa, J; Yamauchi, K, 2009) |
| "A 43 year old man with HIV and HCV infection and liver cirrhosis developed fatal lactic acidosis within five days from starting nifedipine for arterial hypertension." | 7.75 | Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals. ( Mian, P; Moling, O; Pagani, L; Pristerà, R; Rimenti, G; Spoladore, G; Vedovelli, C, 2009) |
| "Nifedipine is a therapeutic drug in acute attacks of hypertension because of its rapid absorption from oral mucosa." | 7.75 | Antihypertensive role of glossopharyngeal nerve stimulation by nifedipine using as calcium channel blocking agent in hypertension: an experimental study. ( Atalay, C; Aydin, MD; Aydin, N; Bayram, E; Gundogdu, C; Halici, Z; Kotan, D; Ulvi, H, 2009) |
| "Nifedipine GITS proved to be effective and well tolerated for the treatment of hypertension in 3003 Chinese patients." | 7.74 | Efficacy and safety of nifedipine GITS in Chinese patients with hypertension--a post-marketing surveillance study. ( Chen, H; He, Q; Huo, Y; Landen, H; Ma, J; Zhang, J, 2007) |
| "Nifedipine GITS proved to be effective and well tolerated for the treatment of hypertension in 7395 Chinese patients under normal daily practice conditions." | 7.74 | Efficacy and safety of nifedipine GITS in Asians with hypertension: results of a post-marketing surveillance study in China. ( Guozhang, L; Junren, Z; Landen, H; Ningling, S; Runlin, G; Tingjie, Z; Weizhong, Z, 2007) |
| "Hypertension in an 83-year-old woman with early Alzheimer disease was treated with a calcium channel blocker, nilvadipine, for 3 months." | 7.74 | Effect of nilvadipine on regional cerebral blood flow in a patient with early Alzheimer disease. ( Araki, N; Imabayashi, E; Kuji, I; Matsuda, H; Ohkubo, T; Shimazu, K, 2008) |
| "Among the L-type calcium channel blockers (CCBs), particularly dihydropyridines like nifedipine [1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester], a common adverse effect is vasodilatory edema." | 7.74 | The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay. ( Black, N; Dhamija, S; Kowala, MC; Liachenko, S; Madore, S; Major, TC; Morenko, B; Okerberg, C; Sobocinski, G; Tinholt, P, 2008) |
| "Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension." | 7.74 | [Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008) |
| "A 77-year-old male with uncontrollable hypertension developed shock, heart block, and multiorgan failure 2 days after clarithromycin was added to his antihypertensive treatment (nifedipine, captopril, doxazosin)." | 7.73 | Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. ( Cortiñas-Sáez, M; Cuartero-del-Pozo, AB; Gerónimo-Pardo, M; Jiménez-Vizuete, JM; Peyró-García, R, 2005) |
| "It is generally agreed that short acting calcium channel blockers (CCB) as nifedipine are not safe as the reflex increase in sympathetic activity and thus, their use in hypertension (HTN) is questionable." | 7.73 | Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine. ( Sweileh, WM, 2005) |
| "The effect of a nifedipine induced reduction in systemic blood pressure on pulse amplitude (PA) as assessed with pneumotonometry and fundus pulsation amplitude (FPA), as measured with laser interferometry was investigated in 16 untreated patients with moderate to severe systemic hypertension (mean arterial pressure 123 (SD 12) mm Hg)." | 7.73 | Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. ( Bayerle-Eder, M; Gasic, S; Kolodjaschna, J; Polska, E; Schmetterer, L; Wolzt, M, 2005) |
| "Nifedipine OROS proved to be effective and well tolerated for the treatment of hypertension in 2044 Chinese patients." | 7.73 | Nifedipine OROS in Chinese patients with hypertension--results of a post-marketing surveillance study in Taiwan. ( Chen, ZC; Hu, SA; Hung, KC; Hung, YJ; Landen, H; Ueng, KC; Yeh, PS, 2005) |
| "This study was designed to examine the hypothesis that a calcium channel blocker nifedipine (CCB) could enhance the cardioprotective effect of an angiotensin-ll receptor blocker candesartan (ARB) in the treatment for heart failure." | 7.73 | Nifedipine enhances the cardioprotective effect of an angiotensin-II receptor blocker in an experimental animal model of heart failure. ( Hayashi, T; Horimoto, H; Inamoto, S; Kitaura, Y; Mieno, S; Mori, T; Okabe, M; Okuda, N, 2005) |
| "Two cases are reported in which depression was associated with the use of calcium channel blocker, nifedipine." | 7.71 | Depression--an adverse event with nifedipine. ( Gandhi, RR; Gohel, DR; Oza, YK; Patalia, AH; Rathod, NR, 2002) |
| "To evaluate the use of short-acting nifedipine for treatment of severe hypertension in children." | 7.71 | The use of short-acting nifedipine in pediatric patients with hypertension. ( Blaszak, RT; Ellis, EN; Savage, JA, 2001) |
| "The objective of the present study was to evaluate the efficacy and safety of a therapeutic interchange between high-dose calcium channel blocker therapy and a fixed-dose combination of amlodipine/ benazepril (Lotrel; Novartis Pharmaceuticals, USA) in patients with moderate to severe hypertension." | 7.71 | Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension. ( Faulkner, M; Hilleman, DE; Reyes, AP; Wurdeman, RL, 2001) |
| "Short-acting nifedipine (SA-NIF) is widely prescribed for acute hypertension (HTN) in children despite reports of ischemic complications in adults." | 7.71 | Adverse neurologic events associated with rebound hypertension after using short-acting nifedipine in childhood hypertension. ( Feldman, HI; Kasner, SE; Leonard, MB; Schulman, SL, 2001) |
| "To assess the effects of a vasodilatory beta-adrenoceptor blocker, nipradilol, and a long-acting Ca channel blocker, barnidipine, on insulin sensitivity." | 7.70 | Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension. ( Awata, T; Inaba, M; Katayama, S; Kosegawa, I; Morita, T, 1998) |
| "Nifedipine is a Ca-antagonist drug that reduces contractility of vascular smooth muscle, and is used in the treatment of arterial hypertension and of stable and vasospastic angina." | 7.70 | Nifedipine and extracellular water in dialysis arterial hypertension. ( Carpinteri, G; Iannetti, E; Trovato, GM, 1998) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 7.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| " Nifedipine treatment in both young and adult hypertensive rats prevented the V3 rise due to hypertension and to the aging process." | 7.70 | Age-related difference in cardiac adaptation to chronic hypertension in rats, with and without nifedipine treatment. ( Malhotra, A; Nakouzi, A; Pathak, D; Raizada, V; Skipper, B, 1999) |
| "Similar lesion topography which resembled an inverted fir tree in two patients with nifedipine-related pemphigus vulgaris is described." | 7.70 | Lesion topography in two cases of nifedipine-related pemphigus. ( Bialy-Golan, A; Brenner, S; Golan, H; Ruocco, V, 1999) |
| "We investigated the regression of left ventricular (LV) hypertrophy with long-term treatment of nifedipine in patients with systemic hypertension." | 7.69 | Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension. ( Maeda, M; Nakano, T; Oonishi, T; Teramura, S; Yamakado, T, 1994) |
| "Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery." | 7.69 | The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994) |
| " Nifedipine is often used to control hypertension in kidney graft recipients." | 7.69 | Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994) |
| "The effect of a single 20 mg sublingual dose of nifedipine on function of proximal tubule of nephron in patients with essential hypertension was studied by measuring changes in renal excretion of water, sodium, uric acid and beta-2-microglobulin (B2m) after nifedipine administration." | 7.69 | [Effect of nifedipine on proximal tubular function in patients with essential hypertension]. ( Pupek-Musialik, D; Rutz, A; Tykarski, A, 1994) |
| "The authors examined the efficacy and safety of the combination of verapamil and nifedipine in the control of hypertension." | 7.69 | Verapamil and nifedipine in combination for the treatment of hypertension. ( Bottini, PB; Carr, AA; Kaesemeyer, WH; Prisant, LM, 1994) |
| " Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)." | 7.69 | [Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995) |
| " Hypertension was treated by nifedipine retard and occasionally by furosemide." | 7.69 | Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation. ( Alivanis, P; Dioudis, C; Goutsaridis, N; Grekas, D; Kalevrosoglou, I; Papoulidou, F; Tourkantonis, A, 1995) |
| "Our purpose was to evaluate the hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies." | 7.69 | Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies. ( Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1996) |
| "The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats." | 7.69 | Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996) |
| "To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug." | 7.69 | 24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997) |
| " Description of their management, usage of nifedipine, and pregnancy outcome." | 7.69 | Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997) |
| "Nifedipine antihypertensive effect was evaluated in 20 patients with essential hypertension." | 7.68 | [A method for determining individual nifedipine sensitivity in treating hypertension patients]. ( Atakhanov, ShE; Baliakina, EV; Gabbasov, ZA; Iurenev, AP; Popov, EG, 1993) |
| "Acute effects of Nifedipine, a calcium channel blocking agent (CCBA), on central haemodynamics in patients with severe hypertension and angiographically proved coronary artery disease (CAD) has been studied using Nuclear Ventriculography (MUGA)." | 7.68 | Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease. ( Bhatia, ML; Jangid, DR; Kasliwal, RR; Trehan, N, 1993) |
| "Patients undergoing kidney transplantation often suffer from essential hypertension and coronary artery disease, for which perioperative treatment with nifedipine proved to be effective." | 7.68 | [Anesthesia for renal transplantation: continuous neuromuscular blockade with atracurium and the management of intraoperative hypertension with nifedipine]. ( Blobner, M; Felber, AR; Gögler, S; Jelen, G; Jelen-Esselborn, S, 1993) |
| "The effect of rectal administration of nifedipine for the management of intraoperative hypertension was studied in 12 adult neurosurgical patients, physical status II and III." | 7.68 | Rectal nifedipine for the management of intraoperative hypertension. ( Gaur, A; Kaushik, S; Pande, RK, 1993) |
| " This study evaluated the influence of aging, superimposed chronic hypertension on aging, and treatment with nifedipine on cardiac myosin isozyme proportions." | 7.68 | Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine. ( Blomquist, TM; Minser, R; Pathak, D; Raizada, V; Woodfin, B, 1993) |
| "Effects of Ca ion channel blockers, nicardipine, diltiazem and nifedipine on intraoperative hypertension were evaluated clinically in ninety surgical patients who received various surgical procedures under total intravenous anesthesia with droperidol, fentanyl and ketamine." | 7.68 | [Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension]. ( Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H, 1993) |
| "The nifedipine gastrointestinal therapeutic system (GITS) was recently approved for use in the treatment of angina and hypertension." | 7.68 | P&T Committee review of nifedipine GITS: new modality for angina and hypertension. ( Horn, J; Krakoff, L; Vetrovec, G; Weintraub, M, 1990) |
| "The antihypertensive effect of slow release nifedipine (CAS 21829-25-4) tablets (20 mg, Adalat) administered once or twice daily was studied in patients with essential hypertension of WHO stage I or II." | 7.68 | Effect of slow release nifedipine tablets in patients with essential hypertension. ( Abe, K; Hashimoto, J; Imai, Y; Minami, N; Munakata, M; Sakuma, H; Sakuma, M; Sasaki, S; Sekino, H; Watanabe, N, 1992) |
| "The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension." | 7.68 | [Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991) |
| " The pressor response to norepinephrine and angiotensin II, as well as several other blood pressure modulating factors, were studied in normal subjects (n = 9) and patients with essential hypertension (n = 10) before and after 8 weeks of treatment with the long-acting dihydropyridine amlodipine." | 7.68 | Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II. ( Beretta-Piccoli, C; Bühler, FR; Donati, L; Heinen, G; Kusch, F, 1992) |
| "Haemodynamic responses at rest and during exercise were studied in 18 patients with essential hypertension following long-term treatment with amlodipine." | 7.68 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1992) |
| "The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients." | 7.68 | Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992) |
| " Nifedipine given in therapeutic doses for the treatment of hypertension was associated with a threefold increase in the ED50 for phenylephrine (92 to 277 ng/min; p less than 0." | 7.68 | Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension. ( Blaschke, TF; Ford, GA; Hoffman, BB; Katzir, D, 1991) |
| "The effects of nifedipine SR and lacidipine on blood pressure, left ventricular (LV) hypertrophy, and diastolic function were evaluated in 15 male patients (mean age of 45 +/- 8 years) with mild-to-moderate hypertension." | 7.68 | Remodeling of left ventricular geometry and function induced by lacidipine and nifedipine SR in mild-to-moderate hypertension. ( Arosio, E; Lechi, A; Montesi, G; Montresor, G; Sheiban, I; Tonni, S, 1991) |
| "7 years, mean +/- SD) received intravenous doses of labetalol, an alpha 1- and beta-adrenergic blocker, on 15 separate occasions for treatment of hypertension." | 7.68 | Intravenously administered labetalol for treatment of hypertension in children. ( Bunchman, TE; Lynch, RE; Wood, EG, 1992) |
| "The prevalence and severity of cough during long-term enalapril treatment were examined by comparing a cohort of 136 hypertensive patients who started treatment with enalapril with consecutive age and sex-matched patients who commenced nifedipine therapy during the same period." | 7.68 | Prevalence of persistent cough during long-term enalapril treatment: controlled study versus nifedipine. ( Foster, G; Ramsay, LE; Yeo, WW, 1991) |
| "In sixteen patients with moderate essential hypertension the effects of 10-day nifedipine treatment on serum uric acid and renal excretion of uric acid were evaluated." | 7.68 | [Uric acid and arterial hypertension. III. Effect of nifedipine on serum uric acid level and its renal excretion in primary arterial hypertension]. ( Tykarski, A, 1991) |
| "Amlodipine administered once daily (5-10 mg) lowered blood pressure and reduced total peripheral resistance in patients with mild-to-severe essential hypertension without any reflex tachycardia." | 7.68 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1991) |
| "In 40 patients (pts) with essential hypertension (EH) the plasma levels of insulin, glucagon, gastrin and prolactin during 2 week therapy with nifedipine were evaluated." | 7.68 | [Essential hypertension. Treatment with nifedipine and levels of insulin, glucagon, gastrin and prolactin]. ( Kokot, F; Wnuk, R, 1991) |
| "The hemodynamic and humoral effects and trough-to-peak 24-hour blood pressure responses of 2 nifedipine formulations, capsules and continuous-release once-daily formulation tablets, were evaluated in 10 patients with mild to moderate essential hypertension." | 7.68 | Hemodynamic comparison of two nifedipine formulations in patients with essential hypertension. ( Frohlich, ED; Ketelhut, R; Losem, CJ; McLoughlin, MJ; Messerli, FH, 1991) |
| "An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension." | 7.68 | Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991) |
| "The short term or acute intravenous administration of nifedipine has been reported to increase urine flow rate and sodium clearance but does not significantly alter the patient's serum or urine electrolytes as other vasodilators." | 7.68 | [Effects of nifedipine, in primary hypertension, on calcium metabolism and on the excretion of the main urinary electrolytes]. ( Ariano, R; Gnocchi, E; Pecchini, F; Rivetti, V, 1991) |
| "Pharmacodynamics and disposition of amlodipine, a dihydropyridine calcium antagonist, were compared between elderly and young patients with hypertension." | 7.68 | Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition. ( Abernethy, DR; Gutkowska, J; Winterbottom, LM, 1990) |
| "The Ca2(+)-ATPase activity and calmodulin (CaM) of erythrocytes and the effect of nifedipine on them were studied in subjects with essential hypertension (EHT)." | 7.68 | [Changes of Ca2(+)-ATPase and calmodulin in erythrocytes and their responses to nifedipine in essential hypertension]. ( Song, K, 1990) |
| "The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension." | 7.68 | Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990) |
| "Clinical, hemodynamic and neurohumoral data are available supporting the validity of a differentiated approach to administration of combined treatment with furosemide, digoxin and calcium antagonists nifedipine and verapamil in advanced-aged patients with hypertension complicated by circulatory disorders." | 7.68 | [Evaluation of the effectiveness of calcium antagonists combined with digoxin and furosemide in hypertension complicated by circulatory insufficiency in elderly patients]. ( Orynchak, MA, 1990) |
| "The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension." | 7.68 | Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990) |
| "Nitrendipine, a calcium entry blocker, was administered by gavage (3 mg/100 g body weight/day) to rats with prolonged angiotensin-II-(AII) induced hypertension." | 7.67 | Nitrendipine reverses vasoconstriction and renal hemodynamic changes in experimental hypertension. ( Huelsemann, JL; McKenzie, DE; Sterzel, RB; Wilcox, CS, 1984) |
| "Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)." | 7.67 | Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984) |
| "The hemodynamic effects of nitrendipine have been studied at rest and during exercise in eight patients with mild to moderate essential hypertension." | 7.67 | Acute and long-term effects of nitrendipine on resting and exercise hemodynamics in essential hypertension. ( Detry, JM; Lavenne, F; Melin, JA; Nannan, ME; Vanbutsele, RJ, 1984) |
| "The efficacy and safety of nitrendipine in oral doses of 5-40 mg twice daily, alone or in combination with hydrochlorothiazide (50-150 mg/day) and/or propranolol (40-120 mg/day), were evaluated in an open study of 50 patients with severe hypertension with supine diastolic blood pressure (BP) greater than 115 mm Hg." | 7.67 | Efficacy and safety of nitrendipine in patients with severe hypertension: a multiclinic study. ( Jain, AK; Maronde, R; McMahon, FG; Mroczek, W; Ryan, JR; Vlachakis, N, 1984) |
| "Thirty-seven white patients of both sexes were studied to determine the efficacy and tolerance of nitrendipine for long ambulatory treatment in patients suffering from mild to moderate essential arterial hypertension whose response to the drug had been effective in a previous study." | 7.67 | Long-term effectiveness of BAY e 5009-nitrendipine in the treatment of mild and moderate arterial hypertension. ( Baglivo, HP; Castro, JM; Esper, RC; Esper, RJ; Menna, J; Rohwedder, RW, 1984) |
| " (160 mg, n = 9) on the pressor effect of the unselective alpha-adrenergic agonist noradrenaline, as well as on 3H-yohimbine binding to platelet alpha 2-adrenoceptors was studied in patients with essential hypertension." | 7.67 | Effect of nifedipine and verapamil on alpha-receptor-activation in patients with essential hypertension. ( Distler, A; Fritschka, E; Kribben, A; Lenz, T; Philipp, T; Schudrowitsch, L, 1984) |
| "Fourteen patients with vascular disease were studied to evaluate the efficacy of nicardipine hydrochloride as a hypotensive agent in the treatment of acute hypertension occurring during anaesthesia." | 7.67 | Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients. ( Furuya, H; Kishi, Y; Okumura, F, 1984) |
| "We observed marked gingival hyperplasia, similar clinically and histologically to the hyperplasia caused by 5:5 sodium diphenylhydantoin (Dilantin) during the last 18 months in five patients treated by nifedipine." | 7.67 | Gingival hyperplasia caused by nifedipine--a preliminary report. ( Behar, S; Engelberg, IS; Kishon, Y; Ramon, Y, 1984) |
| "The use of nifedipine in patients with hypertension, heart failure, and acute myocardial infarction is discussed." | 7.67 | Nifedipine in hypertension and heart failure. ( Matsui, S; Murakami, E; Murakami, H; Takekoshi, N, 1984) |
| "The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium." | 7.67 | Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984) |
| "Weekly subcutaneous implantation of 25-mg nitrendipine pellets prevented onset of both spontaneous and deoxycorticosterone-salt hypertension in rats." | 7.67 | Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets. ( Hall, CE; Hungerford, S, 1984) |
| "Thirteen patients with essential hypertension were started on pindolol 10-20 mg daily and twelve on nifedipine 20-60 mg daily." | 7.67 | Effect of pindolol and nifedipine alone and in combination on haemodynamic parameters/variables in essential hypertension. ( Otsuka, K; Tsukiyama, H; Yamamoto, Y, 1984) |
| " The combination of nitrendipine plus enalapril was also examined in ischemic failure and in rats with spontaneous hypertension." | 7.67 | Enalapril in experimental hypertension and acute heart failure: comparison with calcium channel blockers. ( Adkins, E; Emmert, S; Ludden, CT; Ribeiro, LG; Seymour, AA; Sweet, CS, 1986) |
| "In comparison with a nonspecific vasodilator, sodium nitroprusside (SNP), we intended to deduce the characteristics of nifedipine (NIF) and captopril (CAP) in the treatment of hypertension." | 7.67 | The effects of nifedipine and captopril on renal function in patients with essential hypertension: comparison with sodium nitroprusside. ( Hara, A; Kawai, C; Matsunaga, M; Nakamura, T; Ogawa, K; Pak, CH, 1987) |
| "The acute and chronic hemodynamic effects of nisoldipine were studied in 19 patients (17 men, 2 women; mean age 43 years) with essential hypertension at rest supine and sitting and during steady state 100 W bicycle exercise." | 7.67 | Central hemodynamic effects at rest and during exercise of acute and chronic treatment with nisoldipine in essential hypertension. ( Haugland, H; Lund-Johansen, P; Omvik, P, 1987) |
| "Acute effects of coronary vasodilators (nifedipine, nicardipine, and nitroglycerin) on atrial natriuretic peptide (ANP) and the renin-angiotensin-aldosterone system were studied in normal subjects and patients with essential hypertension." | 7.67 | Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension. ( Aizawa, T; Ishihara, M; Iwasaki, T; Niwa, A; Shinoda, T; Yamada, T, 1989) |
| "In the present study, we report a case of pheochromocytoma whose high blood pressure was well controlled by single-agent therapy with long-acting nifedipine, in spite of the failure of the combination of labetalol and prazosin in lowering blood pressure satisfactorily." | 7.67 | Effectiveness of long-acting nifedipine in pheochromocytoma. ( Fujiwara, R; Kutsumi, Y; Miyabo, S; Nakai, T; Takahashi, S; Tamai, T, 1989) |
| " This hypertension was managed with either prazosin (n = 29) or nifedipine (n = 17)." | 7.67 | Cyclosporine-associated hypertension in cardiopulmonary transplantation. The beneficial effect of nifedipine on renal function. ( Bateman, DN; Dark, JH; Kirk, AJ; Omar, I, 1989) |
| "Electronic data collection was used in this open study to survey the safety and efficacy of nifedipine when used in the treatment of 3972 patients with mild to moderate essential hypertension." | 7.67 | Safety and efficacy of nifedipine 20 mg tablets in hypertension using electronic data collection in general practice. ( Marley, JE, 1989) |
| "The antihypertensive efficacy and effects on body fluid composition of monotherapy with the calcium antagonist nifedipine were investigated in 15 patients with essential hypertension." | 7.67 | Effect of long-term nifedipine treatment on body fluid composition in essential hypertension. ( Andersen, GS; Toftdahl, DB, 1989) |
| "Fifty-two cases of hypertension were treated with verapamil." | 7.67 | [Therapeutic effect of verapamil in hypertension: an analysis of 52 cases]. ( Wang, JJ; Wen, ZB; Zong, JL, 1989) |
| "The influence of nifedipine treatment on plasma (PV) and extracellular fluid volume (ECV), the ratio of plasma volume to interstitial fluid volume (PV:IF), glomerular filtration rate (GFR), renal clearances of Na+ and K+, plasma concentrations of renin (PRC), angiotensin II (pANG II), aldosterone (pAldo), adrenaline (PA) and noradrenaline (PNA) were studied in 18 consecutive patients with essential hypertension." | 7.67 | The influence of nifedipine treatment on counter-regulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Mølbak, AG; Nielsen, F; Nielsen, MD, 1985) |
| "The hemodynamic effects of the slow release form of a calcium channel blocker, nifedipine retard, in essential hypertension patients after angiotensin II (AII) infusion were studied using nuclear ventriculography." | 7.67 | Hemodynamic effects of nifedipine in hypertension in the presence of elevated angiotensin-II and beta-adrenergic blockade. ( Battler, A; Blau, A; Cohen, D; Eldar, M; Eliahou, HE; Iaina, A; Kapuler, S; Neufeld, HN; Rath, S, 1986) |
| "Nifedipine slow release tablets were substituted for minoxidil in the treatment of 13 patients with hypertension refractory to conventional therapy." | 7.67 | Nifedipine substituted for minoxidil in the treatment of refractory hypertension. ( Bing, RF; Heagerty, AM; Swales, JD; Thurston, H, 1987) |
| "Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker." | 7.67 | Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986) |
| "The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age." | 7.67 | Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987) |
| "Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic." | 7.67 | Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986) |
| "The objective of this prospective study was to evaluate the effect of nifedipine administered at usual daily doses of 30 to 40 mg on the carotid flow in arterial hypertension." | 7.67 | [Effects of nifedipine on carotid blood flow and baroreflex response in essential arterial hypertension. Preliminary results]. ( Allal, J; Barraine, R; Baylac-Domengetroy, F; Begon, F; Chaix, AF; Coisne, D; Gallimard, JF; Petitalot, JP, 1986) |
| "Nifedipine was used successfully in nine patients with refractory hypertension and left ventricular hypertrophy who had symptoms of congestive heart failure despite preserved left ventricular systolic function." | 7.67 | Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function. ( Dzau, VJ; Given, BD; Lee, TH; Stone, PH, 1985) |
| "The effects and safety of using sublingually nifedipine 10-20 mg as acute antihypertensive treatment were evaluated in 108 patients with hypertensive emergencies or urgency without intensive care monitoring." | 7.67 | Treatment of hypertensive emergencies with nifedipine. ( Donas, G; Karachalios, GN; Stathakakis, V; Tsimiklis, S, 1988) |
| "Sublingual nifedipine was used for the treatment of acute severe hypertension in 12 children with renal disease." | 7.67 | Sublingual nifedipine in acute severe hypertension. ( Brocklebank, JT; Evans, JH; Shaw, NJ, 1988) |
| "The immediate haemodynamic effects of the calcium antagonist nilvadipine have been studied in ten patients with established mild essential hypertension." | 7.67 | Effect of the calcium antagonist nilvadipine on haemodynamics at rest and during cold stimulation in essential hypertension. ( Hashimoto, N; Hattori, N; Nakamura, S; Ohta, H; Satoh, S; Takabatake, T; Yamada, Y; Yamamoto, Y, 1987) |
| "Acute nifedipine tests and courses of nifedipine treatment were conducted in 30 patients with essential hypertension." | 7.67 | [Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients]. ( Liventseva, MM; Nechesova, TA; Pavlova, AI; Sidorenko, GI, 1988) |
| ") was evaluated as a replacement therapy for long-acting nifedipine (40-120 mg/day) in 21 patients with severe hypertension, who were resistant to or intolerant of nifedipine." | 7.67 | Nisoldipine: a replacement therapy for nifedipine in the treatment of severe hypertension. ( Grossman, E; Rosenthal, T, 1988) |
| "Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women." | 7.67 | Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987) |
| "The effect of nifedipine on plasma lipids given over a period of one month to 14 patients with essential hypertension was studied." | 7.67 | The effect of nifedipine on plasma lipids in patients with essential hypertension. ( Jarvensiven, P; Lehto, H; Lehtonen, A; Tanskanen, A, 1986) |
| "The aim of this study was to investigate the effect of orally administered, slow-release, nifedipine tablets on the circadian rhythm of blood pressure and heart rate, in hospital patients with clinical diagnosis of hypertension validated by a chronobiologic inferential statistic method." | 7.67 | Slow-release nifedipine: effect on the circadian rhythm of blood pressure in essential hypertension. ( degli Uberti, E; Margutti, A; Montanari, L; Pansini, R; Portaluppi, F; Rambaldi, R; Strozzi, C; Trasforini, G, 1987) |
| "To assess the effect of potent vasodilator therapy in patients with severe or resistant hypertension, 10 patients underwent therapy with captopril and nifedipine alone and in combination." | 7.67 | Effects of combination therapy with captopril and nifedipine in severe or resistant hypertension. ( Lane, TJ; Podesla, S; Viadero, JJ; White, WB, 1986) |
| "The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension." | 7.67 | Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986) |
| "The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years." | 7.67 | The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986) |
| "Nifedipine has been used in the management of hypertension in 36 consecutive patients who could not tolerate, or were not controlled by, atenolol and thiazide diuretics." | 7.67 | Use of nifedipine as the drug of third choice in management of hypertension. ( Muir, AL; Roulston, JE; Wathen, CG, 1986) |
| "A new vasodilating agent, minoxidil, was used in 17 patients with essential hypertension that had not responded sufficiently to combined treatment with 3 or 4 conventional hypotensive agents." | 7.67 | [The vasodilator minoxidil in the treatment of hypertension]. ( Iurenev, AP; Nekrasova, AA; Panfilov, VV; Patrusheva, IF, 1987) |
| "The results are reported from the administration of nifedipine to 39 patients with arterial hypertension." | 7.67 | [Nifedipine in the treatment of arterial hypertension]. ( Dimitrova, V; Dzhoneva, S; Monova, D; Simeonova, N; Stoianova, M, 1987) |
| "To assess the role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems in the diuretic and natriuretic actions of nifedipine, a calcium-channel blocker, 20 mg of nifedipine was administered orally to 15 patients with essential hypertension." | 7.67 | Hypotensive and natriuretic effects of nifedipine in essential hypertension. Role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems. ( Abe, K; Kohzuki, M; Kudo, K; Omata, K; Sato, M; Seino, M; Tanno, M; Tsunoda, K; Yasujima, M; Yoshinaga, K, 1986) |
| "The antihypertensive effects of the calcium antagonist diltiazem, both alone and combined with the diuretic mefruside, were assessed over 14 months in 36 patients with essential hypertension." | 7.67 | Effects of diltiazem alone and combined with mefruside on cardiovascular response at rest and during exercise, carbohydrate metabolism and serum lipoproteins in patients with systemic hypertension. ( Distler, A; Gotzen, R; Meyer-Sabellek, W; Röcker, L; Schulte, KL, 1987) |
| "Moderate dietary sodium restriction with moderate dietary potassium supplementation was used in patients with essential hypertension who were treated with nifedipine retard by mouth every twelve hours." | 7.67 | [The combination of nifedipine and a low sodium diet with potassium supplement in the therapy of essential arterial hypertension]. ( Digiesi, V; Parigi, P, 1987) |
| "The results of treating 235 hypertensive patients who had been prescribed nifedipine in a hypertension clinic were examined for factors affecting blood pressure response and the frequency of side-effects." | 7.67 | An audit of nifedipine in a hypertension clinic. ( Beevers, DG; Beevers, M; Gill, JS; Zezulka, AV, 1986) |
| "Felodipine is a new dihydropyridine calcium antagonist, and in hypertension it is a much more effective "third-line" drug than hydralazine." | 7.67 | Felodipine compared to nifedipine as "third-line drug" in resistant hypertension. ( Maclean, D; Mitchell, ET; Readman, AS, 1986) |
| "The radioactive microsphere technique was used to study hemodynamic mechanisms of action of 2 calcium antagonists--foridon and nifedipine in conscious rabbits with acute hypertension evoked by immobilization." | 7.67 | [Hemodynamic mechanisms of the hypotensive action of the new calcium antagonist foridon in acute hypertension in rabbits. A comparison with nifedipine]. ( Dugin, SF; Glukhovtsev, EV; Medvedev, OS, 1986) |
| "The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated." | 7.67 | Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985) |
| "Ten mg of nifedipine was administered to 19 patients with severe hypertension (mean blood pressure 187 +/- 17/122 +/- 12 mm Hg) without intensive care monitoring." | 7.67 | Oral nifedipine for the treatment of patients with severe hypertension. ( Bursten, SL; Davidson, RC; Keeley, PA; Kenny, MA; Stewart, DK, 1985) |
| "The central and peripheral haemodynamic effects of the administration of 10 mg nifedipine sublingually in 6 patients with essential hypertension were compared with those observed after the administration of one 20 mg slow release tablet of nifedipine in 7 other hypertensive patients of the same age." | 7.67 | [Central and peripheral hemodynamic effects of nifedipine administered orally and sublingually in essential arterial hypertension]. ( Bouthier, JD; Levenson, J; Maarek, BC; Safar, ME; Simon, AC, 1985) |
| "To determine the efficacy of nifedipine combined with propranolol in the treatment of hypertension, 23 patients with essential hypertension uncontrolled while they were receiving propranolol, 120 mg/d, entered a dose response trial of four 8-week periods while continuing propranolol therapy." | 7.67 | Effect of nifedipine and propranolol on blood flow, venous compliance and blood pressure in essential hypertension. ( Ogilvie, RI, 1985) |
| "Labile high blood pressure and associated complaints (eg, severe headache, palpitation, and vague discomfort in the chest) in a 28-year-old woman with pheochromocytoma were stabilized by adding nifedipine to the conventional regimen of alpha- and beta-blocking agents." | 7.67 | Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine. ( Chimori, K; Miura, K; Miyazaki, S; Nakajima, T, 1985) |
| "The efficacy of Nifedipine (N) as an antihypertensive drug was assessed in 4 children aged 6-12 years with acute severe hypertension." | 7.67 | [Experiences with nifedipine in the treatment of acute hypertension in childhood]. ( Jüngst, BK; Schranz, D; Stopfkuchen, H; Ziegler, R, 1985) |
| "We present a case of a 79-year-old woman with periods of syncope, complete heart block (CHB), and ventricular standstill during periods of increased vagal tone following sublingual nifedipine for hypertension." | 7.67 | Syncope and conduction disturbances following sublingual nifedipine for hypertension. ( Wolford, R; Zangerle, KF, 1985) |
| "The effect of nifedipine on cellular electrolytes was studied in 14 patients (10 males, 4 females, age 39-62 years) with untreated primary hypertension." | 7.67 | Effect of nifedipine on cellular electrolytes in fourteen patients with untreated primary hypertension. ( Ericsson, F, 1985) |
| " Two cases and a review of the literature relating to treatment of hypertensive emergencies with nifedipine are presented." | 7.67 | Nifedipine in the management of hypertensive emergencies: report of two cases and review of the literature. ( Checcio, LM; Cohan, JA, 1985) |
| "A study was carried out to evaluate the efficacy and tolerance of oral nifedipine in hypertensive emergencies." | 7.67 | Oral nifedipine in hypertensive emergencies. ( Alexander, T; Dennison, D; Jose, J; Mathai, D; Pulimond, BM, 1985) |
| "In 13 patients with essential and renal hypertension, the influence of nifedipine on the intracellular free Ca2+ concentration was tested." | 7.66 | Effect of nifedipine on blood pressure and on intracellular calcium in arterial hypertension. ( Losse, H; Vetter, H; Zidek, W, 1982) |
| "Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 7.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
| "The effect of daily treatment (sometimes interrupted) with the calcium blocker nisoldipine at two different dose levels, one double the other, on the development of spontaneous hypertension in the rat was evaluated." | 7.66 | Prevention of spontaneous and glucocorticoid hypertension in rats by nisoldipine. ( Hall, CE; Hungerford, S, 1983) |
| "Nifedipine, a calcium antagonist with a predominant vasodilator action, was evaluated for the treatment of hypertension." | 7.66 | Nifedipine in the treatment of hypertension. ( Blake, S; Brennan, F; Cannon, P; Flanagan, M, 1983) |
| "The antihypertensive effect of nifedipine (Adalat), a Ca2+-antagonistic drug, was studied in patients with mild or severe hypertension." | 7.66 | Antihypertensive effect of nifedipine and its relationship to severity of hypertension. ( Ashizawa, H; Ijichi, H; Ochi, Y; Shikuma, R; Takahashi, H; Takashina, R; Takeda, K; Yoshimura, M, 1983) |
| "The immediate hemodynamic effects of a new calcium-channel blocking agent nitrendipine were studied in 12 patients with mild established essential hypertension." | 7.66 | Immediate hemodynamic effects of a new calcium-channel blocking agent (nitrendipine) in essential hypertension. ( Dunn, FG; Frohlich, ED; Messerli, FH; Oigman, W; Reisin, E; Ventura, HO, 1983) |
| "Twenty patients with hypertension uncontrolled by existing therapy with two or three antihypertensive agents (a beta-blocker plus a thiazide diuretic in 10 and with the addition of hydralazine or prazosin in the other 10) were studied to assess the effects of additional long-term administration of nifedipine." | 7.66 | Nifedipine in combination therapy for resistant hypertension. ( Beevers, DG; Sloan, PJ, 1983) |
| "The action of nifedipine tablets was examined in 17 patients with essential hypertension focusing particularly on the profile of blood pressure (BP) reduction over 24 hours resulting from both twice-daily and once-daily therapy (dose range 40 to 120 mg daily)." | 7.66 | Nifedipine tablets for systemic hypertension: a study using continuous ambulatory intraarterial recording. ( Gould, BA; Hornung, RS; Jones, RI; Raftery, EB; Sonecha, TN, 1983) |
| "The hypotensive effect of nifedipine was studied in 9 patients with severe hypertension." | 7.66 | Management of severe hypertension with nifedipine in combination with clonidine or propranolol. ( Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Miura, Y; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1980) |
| "16 patients suffering from hypertension and angina pectoris (class II according to the NYHA) are treated with 100 mg atenolol once daily for three weeks." | 7.66 | [Effects of therapy with a association of nifedipine and atenolol in patients with systemic arterial hypertension and angina pectoris]. ( Attisano, N; Grenci, G; Martelli, G; Sarica, G; Schirripa, V, 1982) |
| "The acute and long-term hypotensive effects of low doses of nifedipine, and the correlation between the fall in the blood pressure (BP) and the plasma nifedipine concentration, were investigated in patients with essential hypertension." | 7.66 | Acute and long-term hypotensive effects and plasma concentrations of nifedipine in patients with essential hypertension. ( Aoki, K; Kawaguchi, Y; Sato, K; Yamamoto, M, 1982) |
| "The effects of sublingual nifedipine, a calcium antagonist vasodilator, were assessed in 43 patients with moderate to severe hypertension in an emergency room setting." | 7.66 | Efficacy of sublingual nifedipine in the acute treatment of systemic hypertension. ( Beer, N; Cohen, A; Frishman, W; Gallegos, I; Klein, N; Sonnenblick, E, 1981) |
| "Ten mg of Nifedipine, a Ca++ antagonist, was administered orally in 2 groups of patients; Group 1: 6 patients in hypertensive emergency and Group II: 12 patients with intractable, severe hypertension." | 7.66 | A study on the effects of nifedipine in hypertensive crises and severe hypertension. ( Hada, Y; Kamata, C; Kuramoto, K; Kuwajima, I; Matsushita, S; Murakami, M; Ueda, K, 1978) |
| "Preeclampsia is associated with maternal and perinatal morbidity." | 7.30 | Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features. ( Cleary, EM; Costantine, MM; Kudrimoti, M; Patton, KG; Racchi, NW; Rood, KM, 2023) |
| " If BP is not at goal during 4 week's visit, dosage of antihypertensive agents will be doubled." | 6.94 | A comparative study for the effects of nifedipine GITS and amlodipine besylate administrated in daytime or at nighttime on recovery of blood pressure rhythm and arterial stiffness in the young and middle-aged subjects with non-dipper hypertension (NARRAS) ( Liu, J, 2020) |
| "Background Hypertension is common among patients with Alzheimer disease." | 6.90 | Blood Pressure Lowering With Nilvadipine in Patients With Mild-to-Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension. ( Claassen, JAHR; de Heus, RAA; Donders, R; Lawlor, BA; Olde Rikkert, MGM; Santoso, AMM, 2019) |
| "Nilvadipine treatment lowered systolic blood pressure (Δ=-11." | 6.90 | Effects of Nilvadipine on Cerebral Blood Flow in Patients With Alzheimer Disease. ( Claassen, JAHR; de Heus, RAA; de Jong, DLK; Donders, R; Günther, M; Lawlor, BA; Olde Rikkert, MGM; Rijpma, A; van Osch, MJP, 2019) |
| "A total of 626 patients with preeclampsia were enrolled, screened, and assigned by random to groups receiving either nifedipine + placebo or nifedipine + celastrol orally." | 6.84 | Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial. ( Liang, Y; Wang, D; Xiao, S; Zhang, M, 2017) |
| "The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients." | 6.82 | Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016) |
| " There was a low rate of adverse events in all treatment groups." | 6.82 | Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study. ( Choi, DJ; Kim, DS; Kim, DW; Kim, JH; Lee, HY; Lee, SY; Park, CG; Park, JB; Park, SW; Rim, SJ; Shim, WJ; Shin, JH; Youn, HJ, 2016) |
| "Essential hypertension has been extensively reported to cause endothelial dysfunction." | 6.82 | Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM, 2016) |
| " The primary assessment included the incidence of treatment-emergent adverse events (TEAEs)." | 6.82 | Fixed-dose combination of nifedipine gastrointestinal therapeutic system and candesartan cilexetil in patients with moderate-to-severe essential hypertension: an open-label, long-term safety and efficacy study. ( Dzongowski, P; Kjeldsen, SE; Li, N; Radlmaier, A; Wang, L, 2016) |
| " CR nifedipine (80 mg per day) was generally well tolerated, with the most common drug-related treatment-emergent adverse event being tachycardia (6." | 6.80 | Long-term safety and efficacy of high-dose controlled-release nifedipine (80 mg per day) in Japanese patients with essential hypertension. ( Asano, K; Kajikawa, M; Kimoto, M; Matsuda, Y; Shimamoto, K, 2015) |
| "The current study addresses the 24-h antihypertensive efficacy and safety of arotinolol combined with a different calcium channel blocker." | 6.79 | The efficacy and safety of arotinolol combined with a different calcium channel blocker in the treatment of Chinese patients with essential hypertension: a one-year follow-up study. ( Chen, W; Fang, H; Liu, X; Xu, W, 2014) |
| "Hypertension is associated with endothelial dysfunction and activated Rho-associated kinases (ROCKs)." | 6.77 | Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension. ( Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Iwamoto, Y; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J, 2012) |
| "Nifedipine is a short-acting calcium antagonist formulated into several different oral preparations, each of which may have different effects on haemodynamics and autonomic nervous function." | 6.71 | Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension. ( Andoh, N; Horinaka, S; Ishimitsu, T; Kobayashi, N; Matsuoka, H; Minami, J; Numabe, A, 2004) |
| "Nifedipine was effective in 4 of 18 patients, carvedilol, in 4 of 12 patients (22." | 6.71 | Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trial. ( Angeli, P; Boccagni, P; Burra, P; Carraro, A; Cillo, U; Fagiuoli, S; Fasolato, S; Galioto, A; Gatta, A; Guarda, S; Sartori, M; Semplicini, A; Sticca, A; Zanus, G, 2005) |
| "More enalapril-treated than nifedipine-treated patients required supplemental treatment with hydrochlorothiazide (59% versus 34%, P<0." | 6.70 | Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat ( Bella, JN; Dahlöf, B; De Quattro, V; de Simone, G; Devereux, RB; Hahn, RT; Palmieri, V; Sharpe, N; Walker, JF, 2001) |
| "Fenoldopam seems to be an efficient alternative to nifedipine, especially because of its more rapid onset of action." | 6.69 | DA1-receptor stimulation by fenoldopam in the treatment of postcardiac surgical hypertension. ( Berger, J; Gombotz, H; Mahla, E; Metzler, H; Plaza, J, 1998) |
| "Amlodipine has potential advantages in children since it can be dissolved into a liquid preparation and has a long elimination half-life, allowing for once-daily administration." | 6.69 | A randomized prospective crossover trial of amlodipine in pediatric hypertension. ( Arbus, GS; Blowey, D; Khattak, S; Koren, G; Lyszkiewicz, DA; Rogan, JW, 2000) |
| "Treatment with prazosin GITS did not produce any statistically or clinically significant change in the metabolic parameters at the end of 24 weeks, while with nifedipine SR there was a significant increase in the serum LDL values at 24 weeks (p = 0." | 6.69 | Prazosin GITS vs sustained release nifedipine in patients with hypertension and abnormal lipid profile: a randomized, controlled, multicenter study. Madras Hypertension Study Group. ( Joglekar, SJ; Misra, KP; Mukherjee, S; Nanivadekar, AS, 1998) |
| "Moexipril is a new nonpeptide angiotensin-converting enzyme (ACE) inhibitor with an intermediate duration of action." | 6.68 | Antihypertensive effects of moexipril, a new ACE inhibitor, as add-on therapy to nifedipine in patients with essential hypertension. ( Fox, A; Persson, B; Stimpel, M; Widgren, BR, 1995) |
| "Amlodipine was better tolerated than nifedipine slow release." | 6.68 | Patient compliance and therapeutic coverage: comparison of amlodipine and slow release nifedipine in the treatment of hypertension. The Belgian Collaborative Study Group. ( Block, P; De Backer, G; Degaute, JP; Detry, JM, 1995) |
| "In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased." | 6.68 | Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996) |
| "Nifedipine gastrointestinal therapeutic system (GITS) is a once-a-day formulation of nifedipine providing stable plasma concentrations over the entire 24 h dosing interval." | 6.68 | Efficacy of a low dose nifedipine GITS (20 mg) in patients with mild to moderate hypertension. ( Toal, CB, 1997) |
| " Adverse events, possibly related to drug, were more common with nifedipine SR (34%) than with trandolapril (17%; p < 0." | 6.67 | Comparison of the efficacy and safety of trandolapril and nifedipine SR in mild-to-moderate hypertension. Investigator Study Group. ( Pauly, NC; Steiner, G, 1994) |
| "Carvedilol is a safe, efficient, once/day choice as monotherapy for mild to moderate essential hypertensive patients." | 6.67 | [Use of carvedilol compared to nifedipine in the treatment of mild and moderate essential arterial hypertension]. ( Dantas, M; Freitas, AF; Furtado, MR; Kohlmann, NE; Kohlmann, O; Plavnik, FL; Portela, JE; Spritzer, N; Spritzer, T, 1994) |
| "Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure." | 6.67 | Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994) |
| "Nifedipine and captopril were administered as monotherapy in increasing dosage while a diuretic was added after 8 weeks in patients who failed to reach the target BP (24-h mean diastolic BP < 90 mm Hg) on monotherapy." | 6.67 | Nifedipine versus captopril in the management of moderate hypertension in black patients. ( Davis, J; Eitzman, L; Sareli, P; Skoularigis, J; Strugo, V, 1994) |
| "Treatment with enalapril for 48 months may have a beneficial effect on the decline of microalbumin excretion in NIDDM patients." | 6.67 | Effects of long-term enalapril treatment on persistent micro-albuminuria in well-controlled hypertensive and normotensive NIDDM patients. ( Hara, T; Hotta, N; Kawamura, T; Matsumae, H; Matsuo, S; Nakayama, M; Sakamoto, N; Sano, T; Sasaki, H, 1994) |
| "Nisoldipine, which has a higher coronary vascular selectivity and less negative inotropism than nifedipine, is as effective and as well tolerated as nifedipine in patients whose hypertension is inadequately controlled on atenolol." | 6.67 | Comparison of nisoldipine and nifedipine as additional treatment in hypertension inadequately controlled by atenolol. ( Earle, KA; Hoffbrand, BI; Nievel, JG; Restrick, LJ; Simmonds, NJ, 1993) |
| " Dosing with 25 mg carvedilol once daily or 20 mg nifedipine SR twice daily resulted in mean peak reductions in supine blood pressure of 21/11 and 20/16 mm Hg, respectively, after 1 week of treatment with each respective monotherapy." | 6.67 | Safety of the coadministration of carvedilol and nifedipine sustained-release in the treatment of essential hypertension. ( de Vries Robles, P; Juttmann, JR; Venuti, RP, 1992) |
| " Most adverse events were mild or moderate and the investigators' overall evaluation of tolerability was excellent or good for 91% of patients." | 6.67 | A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice. ( Varrone, J, 1991) |
| "The effects of short- and long-term administration of nifedipine on serum lipids, lipoproteins, and apolipoproteins (apo) were studied." | 6.67 | Effects of short- and long-term administration of nifedipine on serum lipoprotein metabolism in patients with mild hypertension. ( Arakawa, K; Sasaki, J, 1990) |
| "Nilvadipine was well tolerated (only three patients were discontinued due to side effects)." | 6.67 | Evaluation of the clinical pharmacology of nilvadipine in patients with mild to moderate essential hypertension. ( Chen, CF; DeQuattro, V; Douglas, J; Saunders, E; Singh, S; Svetkey, LP; Vlachkis, ND; Weir, MR; Wiedl, SC; Woodward, DL, 1990) |
| "This randomized multicentre study in elderly hypertensives with two unbalanced groups (2 patients under labetalol for 1 patient under nifedipine) compared the efficacy and safety of labetalol, whose dosage could be adjusted (1, 2, then 3 tablets/day) according to blood pressure level (BP greater than or equal to 160/95 mmHg), to that of nifedipine given at its recommended dosage (2 tablets/day)." | 6.67 | [Hypertension in the elderly. Comparison of the efficacy and tolerability of labetalol and nifedipine. A multicenter, randomized, single-blind study]. ( d'Allens, H; Decoulx, M; Godon, P; Pappo, M, 1990) |
| " Sitting (and standing) blood pressure and heart rate one to four hours after dosing were recorded at entry (191/95 mmHg) and at the end of the run-in period (186/93 mmHg)." | 6.67 | Hypertension in the elderly: a study of a combination of atenolol and nifedipine. ( Cheadle, B; Duckett, GK, 1990) |
| "Nifedipine was slightly, but not significantly, more potent." | 6.67 | Verapamil versus nifedipine in slow-release preparations for the treatment of mild to moderate hypertension. ( Meisel, S; Nussinovitch, N; Rosenthal, T; Shamiss, A, 1990) |
| "Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties." | 6.66 | Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988) |
| " Thus amlodipine administered once daily is an effective and safe agent for second-step therapy in mild to moderate essential hypertension." | 6.66 | Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension. ( Chrysant, SG; Glasser, SP; Graves, J; Koehn, DK; Rofman, B, 1989) |
| "We have assessed the efficacy and tolerance of Nifedipine twice daily and Nisoldipine once daily, both alone and in combination with a beta-blocker in 171 essential hypertensives in a randomized parallel comparison fashion." | 6.66 | The efficacy and tolerability of nifedipine (NIF) and nisoldipine (NIS) both alone and combined with a beta-blocker in patients with essential hypertension: a multicenter, parallel-group study. ( Rosenfeld, JB; Zabludowski, J, 1989) |
| "Nifedipine was associated with a significant increase in cardiac output and stroke volume at rest and at peak exercise, while propranolol decreased cardiac output at rest and at peak exercise." | 6.66 | Nifedipine, but not propranolol, improves left ventricular systolic and diastolic function in patients with hypertension. ( Boucher, CA; Christensen, DM; Federman, EB; Miller, DD; Ruddy, TD; Zusman, RM, 1989) |
| "The felodipine treated patients experienced more ankle swelling and flushing than those in the hydralazine group who experienced more headache and minor gastro-intestinal upset." | 6.66 | Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group. ( , 1986) |
| "Bendroflumethiazide 5 mg was given to 17 patients with essential hypertension who had persistent mild to moderate hypertension despite treatment with nifedipine slow-release tablets 20 mg bid." | 6.66 | The effects of bendroflumethiazide added to nifedipine in patients with hypertension. ( Beevers, DG; Gill, JS; Zezulka, AV, 1987) |
| "Nifedipine is a calcium-channel blocker that produces vasodilatation and decreased peripheral resistance in humans." | 6.66 | Double-blind, placebo-controlled trial of twice-daily nifedipine as a step-2 agent in mild essential hypertension. ( Brown, TS; Deterding, J; Gavras, H; Gavras, I; Klotman, PE; Svetkey, LP; Weinberger, MH, 1987) |
| "Nifedipine was well tolerated and appeared to be an effective and safe drug in the treatment of acute rises of blood pressure in infants and children." | 6.66 | Blood pressure and hormonal responses to sublingual nifedipine in acute childhood hypertension. ( Bonzel, KE; Müller-Wiefel, DE; Rascher, W; Ruder, H; Schärer, K, 1986) |
| "Nifedipine therapy was associated with an increase in high-density lipoprotein cholesterol levels and a decrease in serum triglyceride levels." | 6.66 | Comparison of nifedipine and propranolol used in combination with diuretics for the treatment of hypertension. ( Christensen, D; Federman, E; Kochar, MS; McCarron, D; Porush, JG; Spitalewitz, S; Zusman, R, 1987) |
| " Both nisoldipine and the diuretic had a flat dose-response curve." | 6.66 | Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs. ( Daniels, AR; Opie, LH, 1987) |
| "Hypertensive emergencies are a diverse group of disorders characterized by a marked elevation of systemic arterial pressure that is associated with acute end-organ dysfunction." | 6.66 | Efficacy and safety of sublingual nifedipine in hypertensive emergencies. ( Ault, MJ; Ellrodt, AG; Murata, GH; Riedinger, MS, 1985) |
| "Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed." | 6.65 | Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983) |
| "Nicardipine was given three times a day (mean dose: 69." | 6.65 | [Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 6.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| "Nifedipine, 30 mg/day, was added and the dose was titrated upwards to 90 mg/day to achieve normal blood pressure." | 6.65 | The combination of propranolol and nifedipine in the treatment of hypertension: acute and long term effects. ( Ishay, DB; Kobrin, I; Leibel, B; Stessman, J; Yagil, Y, 1983) |
| "Amlodipine has an inherently long pharmacokinetic half-life, whereas, in contrast, nifedipine has an inherently short half-life but in the GITS formulation the sophisticated delivery system allows for once-daily dosing." | 6.48 | Long-acting dihydropyridine calcium-channel blockers and sympathetic nervous system activity in hypertension: a literature review comparing amlodipine and nifedipine GITS. ( Elliott, HL; Meredith, PA; Toal, CB, 2012) |
| "Nifedipine is a dihydropyridine calcium-channel blocker (CCB) introduced approximately 30 years ago for the prophylaxis of angina symptoms, and then later utilized as an anti-hypertensive agent." | 6.45 | Review of nifedipine GITS in the treatment of high risk patients with coronary artery disease and hypertension. ( Beckey, C; Lundy, A; Lutfi, N, 2009) |
| "Calcium antagonists are used in the treatment of hypertension and angina." | 6.44 | The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension. ( Coca, A; Sierra, C, 2008) |
| " However, the short-acting formulations of nifedipine had pharmacokinetic properties that were far from ideal and in 1995, several studies involving various dosing regimens reported possible dangerous effects in secondary prevention." | 6.44 | Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension. ( Dunselman, PH; Kragten, JA, 2007) |
| "Hypertension is an important modifiable risk factor for cardiovascular disease; its prevention and treatment currently represent major health concerns around the world, especially in western countries." | 6.43 | Use of nifedipine in the treatment of hypertension. ( Leoncini, G; Parodi, A; Pontremoli, R, 2005) |
| "Nifedipine is a dihydropyridine calcium channel antagonist with predominantly vasodilatory activity." | 6.43 | Modified-release nifedipine: a review of the use of modified-release formulations in the treatment of hypertension and angina pectoris. ( Croom, KF; Wellington, K, 2006) |
| " The nifedipine gastrointestinal therapeutic system (GITS) formulation provides a once-daily dosing regimen with a continuous and slow release of the drug, resulting in a smooth plasma concentration/time profile." | 6.42 | Clinical use of nifedipine GITS in the treatment of hypertension: an overview. ( Levenson, J; Simon, A, 2003) |
| "The drug is equally effective in treating hypertension in elderly and younger patients and does not appear to adversely affect glucose or lipid metabolism." | 6.39 | Nilvadipine. A review of its pharmacodynamic and pharmacokinetic properties, therapeutic use in hypertension and potential in cerebrovascular disease and angina. ( Brogden, RN; McTavish, D, 1995) |
| " Ambulatory monitoring studies have confirmed that once-daily dosing provides 24-h control of blood pressure." | 6.38 | Amlodipine in the treatment of hypertension. ( Kaplan, NM, 1991) |
| "Nifedipine does cause a long-term reduction in sodium balance." | 6.38 | Nifedipine and systemic hypertension. ( MacGregor, GA, 1989) |
| " Blood pressure control shows a smooth profile over 24 h with once-daily dosing, and there is no tolerance with long-term administration of the drug." | 6.37 | Amlodipine in hypertension: an overview of the clinical dossier. ( Julius, S, 1988) |
| "Nisoldipine is an orally administered calcium entry blocking drug structurally related to nifedipine." | 6.37 | Nisoldipine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Friedel, HA; Sorkin, EM, 1988) |
| "Our objective was to compare cardiovascular event rates in patients with mild or moderate hypertension who received nifedipine with active drug controls." | 6.18 | Safety of nifedipine in patients with hypertension: a meta-analysis. ( Caubet, JF; Chalmers, TC; Luo, D; Niedzwiecki, D; Ross, SD; Schmid, CH; Stason, WB; Whiting, GW, 1997) |
| "Amlodipine is a dihydropyridine calcium antagonist which can be used once daily in hypertension." | 6.16 | Amlodipine: an effective once-daily antihypertensive agent. ( Tyler, HM, 1991) |
| " Nifedipine reduces forearm vascular resistance dose-dependently when infused into the brachial artery in patients with essential hypertension, attesting to its potent arterial vasodilator effects." | 6.16 | Use of nifedipine in hypertension and Raynaud's phenomenon. ( Bühler, FR; Erne, P; Kiowski, W, 1990) |
| " Therapy success: systolic blood pressure ~140 mm Hg and diastolic blood pressure ~90 mm Hg, therapy failure: persistent systolic blood pressure ≥ 160 or diastolic blood pressure ≥ 110 mm Hg after maximum dosage of therapy (EL)." | 5.91 | Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia. ( Dong, W; Peng, Z; Xiao, Y; Zhang, J, 2023) |
| "We evaluated whether combined oral hydrochlorothiazide and lisinopril therapy produced superior short-term blood pressure control when compared with nifedipine among postpartum individuals with hypertension requiring pharmacologic treatment." | 5.69 | Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial. ( Amro, F; Blackwell, SC; Chauhan, SP; Fishel Bartal, M; Lawal, D; Pedroza, C; Samuel, J; Sibai, BM, 2023) |
| "The Giant PANDA study is a pragmatic, open-label, multicentre, randomised controlled trial of a treatment initiation strategy with nifedipine (calcium channel blocker), versus labetalol (mixed alpha/beta blocker) in 2300 women with pregnancy hypertension." | 5.69 | A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA). ( Ashworth, D; Battersby, C; Bick, D; Chappell, LC; Green, M; Hardy, P; Leighton, L; Magee, LA; Maher, A; McManus, RJ; Moakes, C; Morris, RK; Myers, J; Nelson-Piercy, C; Rivero-Arias, O; Sparkes, J; Webb, A; Wilson, H, 2023) |
| "This study aimed to determine if enalapril is superior to nifedipine in preventing prolonged hospitalizations, unplanned medical visits, and/or readmission among women with postpartum hypertension." | 5.69 | A randomized controlled trial comparing the efficacy of nifedipine and enalapril in the postpartum period. ( Celi, AC; McElrath, TF; Robinson, JN; Seely, EW; Yoselevsky, EM, 2023) |
| "The purpose of this research work was to evaluate the Pharmacokinetic (PK), Pharmacodynamic (PD), and the distribution pattern of mucoadhesive microspheres of nifedipine." | 5.62 | Pharmacokinetic and Pharmacodynamic Studies of Nifedipine Loaded Microspheres for the Treatment of Hypertension. ( Garg, R; Gupta, GD; Lal, C, 2021) |
| "Hypertension is a major risk factor for cerebrovascular disease." | 5.62 | Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats. ( Gao, W; Liu, C; Liu, X; Liu, Y; Luo, C; Man, S, 2021) |
| "TCMs combined with Nifedipine sustained-release tablets group generated a total 20-year cost of 11,517." | 5.56 | Cost-effectiveness analysis of combining traditional Chinese medicine in the treatment of hypertension: compound Apocynum tablets combined with Nifedipine sustained-release tablets vs Nifedipine sustained-release tablets alone. ( Feng, S; Guo, J; Hu, M; Liu, QB; Xu, Q; Yang, N, 2020) |
| "The purpose is to investigate the influence of nifedipine, labetalol, and magnesium sulfate on blood pressure control, blood coagulation, and maternal and infant outcome in those suffering from pregnancy-induced hypertension (PIH)." | 5.51 | Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension. ( Gu, S; Shao, Y; Zhang, X, 2022) |
| "In a substudy of a randomized controlled trial, we investigated the effects of the valsartan/amlodipine single-pill combination and nifedipine gastrointestinal therapeutic system (GITS) monotherapy on brachial pulse pressure (bPP) and radial augmentation index (rAI) in patients with previously uncontrolled hypertension." | 5.41 | Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients. ( Chen, LL; Li, Y; Wang, JG; Xie, JH; Xu, SK; Zeng, WF, 2021) |
| " In both age groups, chronic nifedipine administration reduced neurogenic contractions of isolated superior mesenteric artery, but did not significantly affect the dose-response curve to exogenous noradrenaline in 8-week-old rats." | 5.35 | Effect of chronic nifedipine treatment on blood pressure and adrenergic responses of isolated mesenteric artery in young rats with developing spontaneous hypertension. ( Török, J; Zemančíková, A, 2009) |
| " Dosing 3 mg/kg/d cediranib for 4 days induced a marked hypertension of 35 to 50 mmHg." | 5.35 | Inhibition of vascular endothelial growth factor-a signaling induces hypertension: examining the effect of cediranib (recentin; AZD2171) treatment on blood pressure in rat and the use of concomitant antihypertensive therapy. ( Curwen, JO; Kendrew, J; Musgrove, HL; Ogilvie, DJ; Richmond, GH; Wedge, SR, 2008) |
| " Once-daily dosing with nifedipine GITS has been shown to achieve smooth and continuous blood pressure control, identical to conventional first-line diuretic therapy." | 5.33 | Nifedipine gastrointestinal therapeutic system--hypertension management to improve cardiovascular outcomes. ( Heagerty, AM, 2005) |
| " There have been few case reports of adverse events in children." | 5.31 | Evaluation of the safety of short-acting nifedipine in children with hypertension. ( Deming, DD; Egger, DW; Hamada, N; Perkin, RM; Sahney, S, 2002) |
| "To assess the maternal and fetal outcome in women with mild to moderate chronic hypertension on antihypertensive drug (methyldopa or nifedipine) therapy compared to no medication." | 5.30 | Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial. ( Abdallah, S; Gaber, W; Gamal, A; Hamza, H; Marawan, H; Rezk, M; Salama, M, 2019) |
| "To observe and analyze the clinical effect of nifedipine controlled-release tablets combined with valsartan in the treatment of essential hypertension, and to analyze the adverse reactions of patients." | 5.30 | Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension. ( Fu, J; Liu, W; Liu, Y, 2019) |
| "This was a nested cohort study of women with chronic hypertension and a singleton pregnancy recruited to the PANDA (Pregnancy And chronic hypertension: NifeDipine vs lAbetalol as antihypertensive treatment) study at one of three UK maternity units." | 5.30 | Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study. ( Chappell, LC; Cruickshank, JK; Khalil, A; Mills, C; Myers, JE; Nelson-Piercy, C; Seed, PT; Watt-Coote, I; Webster, LM, 2019) |
| "In a pre-specified subgroup analysis of a 12-week randomized multicenter study, we investigated effects of valsartan/amlodipine 80/5 mg single-pill combination (n = 75) and nifedipine GITS 30 mg (n = 75) on ambulatory blood pressure (BP) and arterial stiffness assessed by brachial-ankle pulse wave velocity (PWV) in patients with uncontrolled hypertension." | 5.30 | A randomized multicenter study on ambulatory blood pressure and arterial stiffness in patients treated with valsartan/amlodipine or nifedipine GITS. ( Huang, QF; Li, Y; Sheng, CS; Wang, JG; Xu, SK; Zeng, WF, 2019) |
| "In a multicenter, randomized trial, we investigated whether the long half-time dihydropyridine calcium channel blocker amlodipine was more efficacious than the gastrointestinal therapeutic system (GITS) formulation of nifedipine in lowering ambulatory blood pressure (BP) in sustained hypertension (clinic systolic/diastolic BP 140-179/90-109 mm Hg and 24-hour systolic/diastolic BP ≥ 130/80 mm Hg)." | 5.30 | A randomized controlled trial on the blood pressure-lowering effect of amlodipine and nifedipine-GITS in sustained hypertension. ( Dou, Y; Huang, QF; Li, Y; Sheng, CS; Wang, JG; Zheng, MS; Zhu, ZM, 2019) |
| "Hypertension is frequently associated to abdominal obesity, and hyperinsulinism could play a role in its pathogenesis." | 5.30 | Effects of 3-month nifedipine treatment on endocrine-metabolic parameters in patients with abdominal obesity and mild hypertension. ( Avogadri, E; Camanni, F; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M; Rossetto, R, 1998) |
| " For both drug classes, we suggest that long-acting agents be considered, providing therapeutic coverage well beyond the normal dosing interval." | 5.29 | 1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart? ( Leenen, FH, 1996) |
| "Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg." | 5.28 | Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992) |
| "Treatment of severe hypertension is beneficial, but reversibility of target-organ damage has not been characterized." | 5.28 | Effect of nifedipine GITS on left ventricular mass and diastolic function in severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991) |
| " It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency." | 5.28 | Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990) |
| "Nifedipine was withdrawn due to a considerable increase in heart rate in three patients and skin allergy in one." | 5.28 | Acute and long-term treatment of hypertension with nifedipine in the elderly. ( Czarnecka, D; Dubiel, JP; Grodzicki, T; Kawecka-Jaszcz, K; Kocemba, J; Skalska, A; Skoczen, M; Witek, J, 1990) |
| "Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents." | 5.28 | [Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990) |
| "Nifedipine appears to be a promising agent for the prehospital treatment of severe hypertension, but its proper role is not yet defined." | 5.28 | Prehospital use of nifedipine for severe hypertension. ( Duda, J; Heller, MB; Kaplan, R; Maha, RJ; Menegazzi, J; Paris, PM; Stewart, RB, 1990) |
| "Nifedipine did not produce any depression of contractile and pump functions of the heart." | 5.28 | [Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects]. ( Bobrov, VA; Konoshevich, SN, 1989) |
| "Pretreatment with captopril in a dose of 25 mg." | 5.28 | Captopril--nifedipine interaction in hypertension. ( Dadkar, VN; Dhar, HL; Khokhani, RC; Moulick, ND, 1989) |
| " Adverse reactions may be reduced by the use of long-acting nifedipine, which would permit a reduction in the dosage of captopril and minoxidil." | 5.27 | Long acting nifedipine in the treatment of severe hypertension. ( Bursztyn, M; Grossmann, E; Rosenthal, T, 1984) |
| "Fifteen males with previously untreated essential hypertension in WHO stage I, aged 20-64 years were studied on an outpatient basis." | 5.27 | Haemodynamic effects of nifedipine in essential hypertension at rest and during exercise. ( Lund-Johansen, P; Omvik, P, 1983) |
| "When felodipine was given as single drug to 14 previously untreated hypertensives in a single-blind manner, BP was rapidly reduced by about 15% while HR increased by 25%." | 5.27 | Short-term effects of felodipine, a new dihydropyridine, in hypertension. ( Aberg, H; Andersson, O; Bengtsson, C; Elmfeldt, D; Haglund, K; Hedner, T; Ostman, J; Seideman, P; Sjöberg, KH; Strömgren, E, 1984) |
| "Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal experiment." | 5.27 | Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension. ( Garthoff, B; Kazda, S; Knorr, A, 1983) |
| "Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis." | 5.27 | The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988) |
| "Felodipine, a new dihydropyridine, was given to 58 hypertensive patients in combination with an adrenergic beta-receptor antagonist and a diuretic agent." | 5.27 | Long term experience of felodipine in combination with beta-blockade and diuretics in refractory hypertension. ( Collste, P; Danielsson, M; Elmfeldt, D; Feleke, E; Gelin, A; Hedner, T; Rydén, L, 1985) |
| " Nine patients were treated for 42 days at a fixed dosage of 1 tablet/day." | 5.27 | [Nitrendipine, a new calcium antagonist, in the therapy of arterial hypertension]. ( Aimi, M; Bianco, C; Conti, G; Corbacelli, C; Cosmi, F; Mollaioli, M; Ricca, M, 1985) |
| "Nifedipine was administered to treat arterial hypertension (greater than 180 mm Hg, systolic)." | 5.27 | Effects of nifedipine on intracranial pressure in neurosurgical patients with arterial hypertension. ( Sano, T; Suzuki, T; Takeshita, H; Tateishi, A; Tokuno, H, 1988) |
| "Two women with preeclampsia treated unsuccessfully with alpha-methyldopa and magnesium sulfate became profoundly hypotensive when oral nifedipine was added." | 5.27 | Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia? ( Cámera, MI; Martinotti, A; Mayorga, LM; Vignolo, CA; Waisman, GD, 1988) |
| "Treatment of hypertension in systemic lupus erythematosus (SLE) may be complicated by unwanted immunologic vascular and renal side effects of drugs." | 5.27 | Nifedipine in the treatment of hypertension in systemic lupus erythematosus. ( Bursztyn, M; Many, A; Rosenthal, T, 1987) |
| "Nifedipine monotherapy was problematic because of side-effects and development of resistance to therapy after a few months." | 5.26 | Long-term therapy of arterial hypertension with nifedipine given alone or in combination with a beta-adrenoceptor blocking agent. ( Christensen, CK; Husted, SE; Lederballe Pedersen, O; Nielsen, HK, 1982) |
| "When nifedipine was given to rats at a dosage of 0." | 5.26 | Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine. ( Hall, CE; Hungerford, S, 1982) |
| "The hypotensive effect of nifedipine (a Ca2+-antagonist) was studied in acute tests and during the long-term administration of the drug together with propranolol." | 5.26 | Hypotensive action of nifedipine (Ca2+-antagonist) and propranolol in acute trials and its long-term therapy of hypertensive coronary heart disease patients. ( Aoki, K; Kato, K; Kawaguchi, Y; Kondo, S; Mochizuki, A; Sato, K; Yamamoto, M, 1981) |
| " The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine." | 5.26 | Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979) |
| "The objective of the study was to investigate the relationship between baseline blood pressure (BP) and the magnitude of BP reduction in patients with essential hypertension treated with nifedipine gastrointestinal therapeutic system (NGTS)." | 5.24 | Impact of baseline blood pressure on the magnitude of blood pressure lowering by nifedipine gastrointestinal therapeutic system: refreshing the Wilder's principle. ( Cui, W; Gu, G; Hu, H; Liu, D; Tian, Z; Wang, Y; Xie, R; Zhang, G; Zhang, J; Zheng, H, 2017) |
| "To determine whether oral labetalol is associated with a shorter time to blood pressure control compared to oral extended release nifedipine for management of persistent postpartum hypertension." | 5.24 | Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial. ( Greene, N; Kilpatrick, SJ; Sharma, KJ, 2017) |
| "There is a lack of sufficient evidence regarding efficacy and safety of amlodipine on treating hypertension during pregnancy." | 5.22 | Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis. ( Du, P; Mei, Z; Qin, S; Shi, S; Yin, J, 2022) |
| "This network meta-analysis aimed to compare the efficacy and safety of intravenous (IV) hydralazine, oral nifedipine, and IV labetalol with different dosage regimens in the treatment of severe hypertension during pregnancy." | 5.22 | Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials. ( Cheng, Y; Jiang, YF; Li, JB; Wu, HZ; Yu, D; Zhu, ZN, 2022) |
| " Methyldopa, labetalol, and nifedipine have been perceived safe to use during pregnancy and are therefore recommended in international guidelines for treatment of hypertension." | 5.22 | Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review. ( Allegaert, K; Flint, RB; Mian, P; Schoenmakers, S; van de Vusse, D; Versmissen, J; Visser, W, 2022) |
| "Patients with hypertension who received a daily nifedipine GITS dose of 60 mg, either at constant dose (n = 686) or up-titrated from 30 mg (n = 392), were analyzed." | 5.22 | Combination therapy with nifedipine GITS 60 mg: subanalysis of a prospective, 12-week observational study (AdADOSE). ( Dello, Z; Hussain, W; Motaweih, AK; Petri, T; Usova, E, 2016) |
| "In the present study, the efficacy and safety of oral nifedipine and intravenous labetalol for severe pre-eclampsia therapy were compared." | 5.22 | Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia. ( Shi, DD; Wang, N; Yang, FZ; Zhou, L, 2016) |
| "The aim of this study was to evaluate the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus." | 5.20 | Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Dario Ragonesi, P; Derosa, G; Franzetti, I; Maffioli, P; Querci, F, 2015) |
| "The aim of this study was to evaluate the effects of lercanidipine or barnidipine on echocardiographic parameters, in hypertensive, type 2 diabetics with left ventricular hypertrophy." | 5.20 | Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial. ( D'Angelo, A; Derosa, G; Franzetti, I; Maffioli, P; Mugellini, A; Pesce, RM; Querci, F, 2015) |
| " This study investigated the effects of a low-dose combination of nifedipine Gastrointestinal Therapeutic System (GITS) and valsartan versus high-dose monotherapy with either agent in reducing central BP in essential hypertension inadequately controlled by low-dose monotherapy." | 5.19 | Randomized trial comparing the effects of a low-dose combination of nifedipine GITS and valsartan versus high-dose monotherapy on central hemodynamics in patients with inadequately controlled hypertension: FOCUS study. ( Ha, JW; Jung, HO; Park, JB; Rhee, MY, 2014) |
| " We planned to research the effect of vitamin D and nifedipine in the treatment of patients with essential hypertension." | 5.19 | Vitamin D and nifedipine in the treatment of Chinese patients with grades I-II essential hypertension: a randomized placebo-controlled trial. ( Chen, WR; Chen, YD; Liu, ZY; Sha, Y; Shi, Y; Wang, H; Yin, DW, 2014) |
| "DISTINCT (reDefining Intervention with Studies Testing Innovative Nifedipine GITS - Candesartan Therapy) aimed to determine the dose-response and tolerability of nifedipine GITS and/or candesartan cilexetil therapy in participants with hypertension." | 5.19 | Nifedipine plus candesartan combination increases blood pressure control regardless of race and improves the side effect profile: DISTINCT randomized trial results. ( Cha, G; Gil-Extremera, B; Haller, H; Harvey, P; Heyvaert, F; Kjeldsen, SE; Lewin, AJ; Mancia, G; Sica, D; Villa, G, 2014) |
| "The paper represents the dynamics of hemostasis values in 42 patients with arterial hypertension of the second stage in complex treatment with combined drug tonorma (atenolon - 100 mg, nifedipine - 10 mg, chlorthalidone - 25 mg)." | 5.19 | [Dynamics of the hemostasis parameters in patients with arterial hypertension in treatment with combined antihypertensive agents]. ( Bula, MS; Virna, MM; Zaremba, IeKh; Zaremba, OV; Zaremba-Fedchyshyn, OV, 2014) |
| "In this multicenter, open-label, active-controlled, parallel-group study, 564 patients with hypertension not adequately controlled by prior monotherapy were randomized to receive valsartan/amlodipine 80/5 mg or nifedipine GITS 30 mg once daily for 12 weeks." | 5.17 | Valsartan/amlodipine compared to nifedipine GITS in patients with hypertension inadequately controlled by monotherapy. ( Chen, LL; He, YS; Li, Y; Li, ZP; Wang, JG; Wei, M; Zeng, WF; Zhang, BW, 2013) |
| "Patients aged 30 to 59 years with untreated stage 1 essential hypertension and a family history of hypertension were treated with the antihypertensive agents candesartan (n = 124) or nifedipine CR (n = 120)." | 5.17 | Feasibility of regression of hypertension using contemporary antihypertensive agents. ( Itoh, H; Julius, S; Murakami, M; Nakaya, H; Ryuzaki, M; Sasamura, H; Sato, Y; Takahashi, F; Takeuchi, M; Tomotsugu, N, 2013) |
| "It is revealed that only nifedipine CR and cilnidipine could reduce albuminuria statistically." | 5.17 | A crossover comparison of urinary albumin excretion as a new surrogate marker for cardiovascular disease among 4 types of calcium channel blockers. ( Arakawa, K; Fujii, M; Inoki, I; Kimura, T; Konoshita, T; Makino, Y; Miyamori, I; Morikawa, N; Nakamura, H; Wakahara, S, 2013) |
| " In the present analysis, we used data from the TALENT study to evaluate soluble receptor for advanced glycation end-products (sRAGE) plasma levels in patients with hypertension and high-cardiovascular risk-treated nifedipine and telmisartan in combination." | 5.16 | Microalbuminuria and sRAGE in high-risk hypertensive patients treated with nifedipine/telmisartan combination treatment: a substudy of TALENT. ( Boiocchi, C; Bozzini, S; Buzzi, MP; Choi, J; D'Angelo, A; Esposito, C; Falcone, C; Mancia, G; Ochan Kilama, M; Schirinzi, S; Torreggiani, M, 2012) |
| "ADVISE was a 12-week, multicenter, randomized, prospective, open-label, parallel-group study comparing combination therapy of nifedipine GITS 30 mg plus valsartan 80 mg (N + V) with high-dose valsartan (160 mg) monotherapy (V160) in Asian patients with hypertension." | 5.16 | Improved blood pressure control with nifedipine GITS/valsartan combination versus high-dose valsartan monotherapy in mild-to-moderate hypertensive patients from Asia: results from the ADVISE study, a randomized trial. ( Baek, SH; Dong, YG; Ihm, SH; Ke, YN; Ma, SP; Yuan, H, 2012) |
| "A retrospective analysis of the database from A Coronary Disease Trial Investigating Outcome with Nifedipine (ACTION) evaluated the effectiveness of nifedipine gastrointestinal therapeutic system (GITS) (i) in combination with renin angiotensin system (RAS) blockers and (ii) in patients with isolated systolic hypertension (ISH)." | 5.15 | Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina. ( Elliott, HL; Meredith, PA, 2011) |
| "Intravenous hydralazine is a commonly administered arteriolar vasodilator that is effective for hypertensive emergencies associated with pregnancy." | 5.15 | Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy. ( Esmaeili, S; Khazaeipour, Z; Motevalian, M; Pourmojieb, M; Rezaei, Z; Sharbaf, FR; Youefzadeh-Fard, Y, 2011) |
| "The aim of this study was to compare the effects of nifedipine coat-core (once daily formulation) and amlodipine on systemic arterial stiffness in patients with hypertension." | 5.14 | Influence of nifedipine coat-core and amlodipine on systemic arterial stiffness modulated by sympathetic and parasympathetic activity in hypertensive patients. ( Fukuda, M; Ishii, A; Izumi, T; Masuda, T; Moriya, T; Noda, C; Ogura, MN; Tanaka, K; Yamamoto, K; Yonezawa, R, 2009) |
| "We compared antihypertensive effects and organoprotective action of a calcium antagonist nifedipine RD and angiotensin converting enzyme (ACE) inhibitor enalapril in subjects older than 60 years with systolic diastolic (group 1) and isolated (group 2) I-II degree arterial hypertension." | 5.14 | [Comparative assessment of a calcium antagonist with controlled release of nifedipine and enalapril in arterial hypertension in subjects older than 60 years]. ( Borisova, NA; Fadeeva, SS; Grishaeva, EE; Iastrebova, EI; Oleĭnikov, VE, 2009) |
| " This trial investigated the antihypertensive efficacy and effects on the morning BP surge of awakening versus bedtime administration of nifedipine in essential hypertension." | 5.14 | Reduction of morning blood pressure surge after treatment with nifedipine GITS at bedtime, but not upon awakening, in essential hypertension. ( Alonso, I; Ayala, DE; Fernández, JR; Hermida, RC; Mojón, A, 2009) |
| " Patients with essential hypertension and a blood pressure > 140/90 mmHg on ARB monotherapy (losartan 50 mg/day or candesartan 8 mg/day) were randomly assigned to a nifedipine controlled release (CR) group (n = 15) or amlodipine group (n = 11)." | 5.14 | Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment. ( Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y, 2009) |
| "Hypertensive patients with coronary artery disease were randomly assigned to the nifedipine retard (n = 108) or ACE inhibitors groups (n = 102) and treated for 3 years." | 5.14 | Reverse remodeling and improved function by antihypertensive treatment in hypertensive patients with coronary artery disease. ( Haze, K; Hirayama, A; Hosoda, S; Iwanaga, Y; Kawai, C; Kodama, K; Nishio, R; Nonogi, H; Sumiyoshi, T; Yui, N; Yui, Y, 2010) |
| "This study investigated the effectiveness and tolerability of barnidipine 10 or 20 mg added to losartan 50 mg versus losartan 100 mg alone in patients with mild to moderate essential hypertension whose BP was uncontrolled by losartan 50-mg monotherapy." | 5.14 | Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-grou ( Cagnoni, F; Destro, M; Giglio, A; Grandi, AM; Lonati, L; Maresca, AM; Monza, M; Omboni, S; Parati, G; Pini, C; Ricci, AR; Venco, A, 2010) |
| "In this study, we primarily aimed to identify the acute effects of hypertension on fibrinolytic function in previously untreated urgent hypertensive patients and to evaluate the influence of two commonly used, short-acting, anti-hypertensive agents, captopril and nifedipine, in these patients." | 5.14 | Plasma plasminogen activator inhibitor 1 (PAI-1) and P-selectin levels in urgent hypertension: effect of single dose captopril and nifedipine on fibrinolytic activity. ( Buyukhatipoglu, H; Tiryaki, O; Usalan, C, 2010) |
| "The aim of this study was to compare nifedipine and carvedilol in the treatment of de novo arterial hypertension after orthotopic liver transplantation (OLT)." | 5.13 | Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial. ( Angeli, P; Boccagni, P; Cillo, U; Fasolato, S; Frigo, AC; Galioto, A; Gatta, A; Semplicini, A; Sticca, A; Zanus, G, 2008) |
| "The increased efficacy on ambulatory BP as well as the significantly reduced prevalence of edema after bedtime as compared to morning ingestion of nifedipine should be taken into account when prescribing this medication to patients with essential hypertension." | 5.13 | Chronotherapy with nifedipine GITS in hypertensive patients: improved efficacy and safety with bedtime dosing. ( Ayala, DE; Fernández, JR; Hermida, RC; Mojón, A, 2008) |
| "The TOlerabilidad de LERcanidipino 20 mg frente a Amlodipino y Nifedipino en CondicionEs normales de uso study was aimed to compare the tolerability of high doses of lercanidipine with amlodipine and nifedipine gastro-intestinal therapeutic system (GITS) in the treatment of hypertension in daily clinical practice." | 5.13 | High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study. ( Barrios, V; Calderón, A; de la Figuera, M; Escobar, C; Honorato, J; Llisterri, JL; Segura, J, 2008) |
| "The TOLERANCE study was aimed to compare the tolerability of high doses of lercanidipine (20 mg) with that of other frequently used dihydropyridines (amlodipine 10 mg/nifedipine GITS 60 mg) in the treatment of essential hypertension in daily clinical practice." | 5.13 | Tolerability of high doses of lercanidipine versus high doses of other dihydropyridines in daily clinical practice: the TOLERANCE Study. ( Barrios, V; Calderón, A; de la Figuera, M; Escobar, C; Honorato, J; Llisterri, JL; Segura, J, 2008) |
| "We investigated whether long-term treatment with the angiotensin-converting enzyme (ACE) inhibitor imidapril or the calcium channel antagonist nifedipine increases systemic nitric oxide (NO) production in patients with essential hypertension." | 5.12 | Long-term treatment with imidapril but not with nifedipine enhances plasma NOx concentration in patients with essential hypertension. ( Horiuchi, M; Kouzuma, R; Mizuki, T; Morishita, T; Nakashima, Y; Nakata, S; Okazaki, M; Suda, O; Sumiyama-Fujinishi, A; Tasaki, H; Tsutsui, M; Yanagihara, N, 2006) |
| "In patients with MS and mild hypertension monotherapy with spirapril and combination of spirapril with nifedipine retard caused lowering of BP to target level in 55 and 90%, respectively." | 5.12 | [Rational approach to selection of antihypertensive therapy in persons with metabolic syndrome: efficacy of monotherapy with spirapril and its combination with retard form of nifedipine]. ( Kiseleva, NV; Mamedov, MN, 2006) |
| "A 64-year old patient with well controlled essential hypertension reported convincingly that oral yohimbine had beneficial acute effects in treating his erectile dysfunction." | 5.12 | [Individualising the evidence--single case randomized trial]. ( Haefeli, WE, 2006) |
| "Essential hypertension is associated with enhanced biological activity of endothelin-1 (ET-1) and impaired endothelium-dependent vasodilatation." | 5.12 | Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension. ( Corti, R; Luscher, TF; Noll, G; Salvetti, A; Spieker, L; Sudano, I; Taddei, S; Virdis, A, 2007) |
| "We compared the effects of nilvadipine and amlodipine on the cognitive function and regional cerebral blood flow (rCBF) in patients with mild cognitive impairment (MCI) and hypertension." | 5.12 | Favourable effects of nilvadipine on cognitive function and regional cerebral blood flow on SPECT in hypertensive patients with mild cognitive impairment. ( Abe, K; Hanyu, H; Hirao, K; Iwamoto, T; Koizumi, K; Shimizu, S, 2007) |
| "We examined the effect of a Ca antagonist (nilvadipine) on the occurrence or recurrence of symptomatic stroke in hypertensive patients with MRI-defined asymptomatic cerebral infarction (ACI), periventricular hyperintensity (PVH), and deep and subcortical white matter hyperintensity (DSWMH), with or without a history of stroke, and evaluated the effect of long-term treatment on the lesions." | 5.12 | Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment. ( Fukuuchi, Y; Hirai, S; Okudera, T; Shinohara, Y; Terashi, A; Tohgi, H; Yamaguchi, T, 2007) |
| "Amlodipine and nifedipine CR were administered to 41 patients with essential hypertension for more than 6 weeks each in a randomized open-label crossover study." | 5.12 | Crossover study of amlodipine versus nifedipine CR with home blood pressure monitoring via cellular phone: internet-mediated open-label crossover trial of calcium channel blockers for hypertension (i-TECHO trial). ( Itagaki, K; Nakajima, S; Nakamoto, H; Nishida, E; Ryuzaki, M; Sone, M; Suzuki, Y; Yoshimoto, M, 2007) |
| " This multicenter, randomized, double-blind study was aimed at testing the efficacy and safety of the combination of low-dose nifedipine GITS 20 mg/ losartan 50 mg compared with either monotherapy in patients with grade 1 to 3 hypertension over an eight-week period." | 5.11 | Effects of the combination of low-dose nifedipine GITS 20 mg and losartan 50 mg in patients with mild to moderate hypertension. ( Bendersky, M; Grassi, G; Guzman, L; Kuschnir, E; Mancia, G; Pañart, MS; Plotquin, Y; Resk, J; Wagener, G, 2004) |
| "The Japan Multicenter Investigation for Cardiovascular Diseases-B was performed to investigate whether nifedipine retard treatment was associated with a significantly higher incidence of cardiac events than angiotensin converting enzyme inhibitor treatment in Japanese patients." | 5.11 | Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial. ( Arakawa, K; Hirayama, A; Hosoda, S; Iimura, O; Ishii, M; Kanmatsuse, K; Kawai, C; Kodama, K; Nonogi, H; Origasa, H; Saruta, T; Sumiyoshi, T; Yui, Y, 2004) |
| "We evaluated the effects of 4 weeks of treatment with low-dose nifedipine gastrointestinal therapeutic system (GITS; 20 mg/day) compared with placebo on muscle sympathetic nerve activity and plasma noradrenaline, in relation to changes in plasma renin activity and plasma angiotensin II and blood pressure in young and older patients with mild hypertension." | 5.11 | Effects of low-dose nifedipine GITS on sympathetic activity in young and older patients with hypertension. ( Coletta, E; Floras, J; Leenen, FH; Ruzicka, M, 2004) |
| "Twenty-four patients with hypertension were assigned, in a random crossover fashion, to a sequence of bendroflumethiazide, nifedipine LA and enalapril, each for 4 weeks, followed by a 1-week period of dose omission." | 5.11 | Comparison of the effects of a 7-day period of non-compliance on blood pressure control using three different antihypertensive agents. ( Girvin, BG; Johnston, GD, 2004) |
| "This study was conducted to evaluate blood pressure control glucose homeostasis, and the plasma lipid profile in patients with type 2 diabetes mellitus and mild hypertension during 12 months of treatment with the ARB telmisartan or nifedipine gastrointestinal therapeutic system (GITS)." | 5.11 | Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doubl ( Bertone, G; Ciccarelli, L; Cicero, AF; Derosa, G; Fogari, E; Fogari, R; Piccinni, MN, 2004) |
| "To assess the efficacy of an angiotensin converting enzyme (ACE) inhibitor (perindopril), a dihydropyridine calcium channel blocker (sustained release nifedipine) and placebo in preventing the progression of albuminuria and decline in glomerular filtration rate (GFR) in patients with Type 2 diabetes and microalbuminaria." | 5.11 | Long-term renoprotection by perindopril or nifedipine in non-hypertensive patients with Type 2 diabetes and microalbuminuria. ( Allen, TJ; Campbell, DJ; Cooper, ME; Gilbert, RE; Hammond, JJ; Jerums, G; O'Brien, RC; Raffaele, J; Tsalamandris, C, 2004) |
| "Forty-one patients (54 +/- 3 years of age, 20 men and 21 women) with essential hypertension (155 +/- 3/95 +/- 3 mm Hg) were randomly allocated to the treatment with valsartan (80 mg once daily) or nifedipine coat-core (20 mg once daily)." | 5.11 | Effects of valsartan and nifedipine coat-core on systemic arterial stiffness in hypertensive patients. ( Kato, H; Munakata, M; Nagasaki, A; Nunokawa, T; Sakuma, T; Toyota, T; Yoshinaga, K, 2004) |
| "This study tested the effects on cardiovascular outcomes of treatments based on nifedipine gastrointestinal therapeutic system (GITS) compared with the diuretic combination co-amilozide in a pre-specified subset of patients with isolated systolic hypertension (ISH) enrolled in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT) study." | 5.11 | Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study. ( Brown, M; Castaigne, A; De Leeuw, P; Mancia, G; Palmer, C; Rosental, T; Ruilope, L; Wagener, G, 2004) |
| "These findings suggest that the low-dose combination therapy of nifedipine CR and candesartan is superior to the up-titrated monotherapy of candesartan in terms of blood pressure control and renal protection in patients with essential hypertension." | 5.11 | Controlled-release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: the NICE Combi (Nifedipine and Candesartan Combination) Study. ( Hasebe, N; Kikuchi, K, 2005) |
| "The salutary effects of the addition of nifedipine GITS to the basic regimen of patients with concurrent stable symptomatic coronary artery disease and hypertension emphasize the need for blood pressure control." | 5.11 | Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension: the ACTION trial. ( de Brouwer, S; Kirwan, BA; Lubsen, J; Poole-Wilson, PA; Wagener, G, 2005) |
| "This study compares the effects of telmisartan hydrochlorothiazide (HCTZ) combination versus nifedipine GITS on ambulatory blood pressure (BP) and sympathetic activity, in patients with mild-to-moderate hypertension." | 5.11 | Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation. ( Corradi, L; Fogari, R; Mugellini, A; Pasotti, C; Preti, P; Rinaldi, A; Zoppi, A, 2005) |
| "This randomized, double-blind, multicentre trial compared the blood pressure lowering effects of a 12-week treatment of nifedipine GITS 20 mg vs enalapril 20 mg in 264 patients with mild-to-moderate hypertension." | 5.11 | Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension. ( Agabiti Rosei, E; Morelli, P; Rizzoni, D, 2005) |
| "This study assessed and compared the effects of Balsamodendron mukul (an extract of the gum of a small tree) and nifedipine (a calcium-channel-blocking reference drug) on blood pressure, lipids, lipoproteins, and phospholipids in randomly selected patients with essential hypertension." | 5.11 | Single- or double-blind treatment With Balsamodendron mukul and nifedipine in hypertensive patients. ( Nalini, N; Panneerselvam, J; Sambandam, G, 2005) |
| "To compare the efficacy and tolerability of bisoprolol, enalapril and nifedipine retard in the treatment of mild to moderate essential hypertension." | 5.10 | Efficacy of domestic bisoprolol,enalapril and nifedipine retard in mild to moderate hypertension: a randomized double-blind multicenter clinical trial in China. ( Li, M; Liu, G; Shi, X, 2002) |
| "The purpose of this study was to determine whether the slower- and longer-acting nifedipine tablets were as effective and safe as the rapid onset and short-acting nifedipine capsules for the treatment of acute severe hypertension in pregnancy." | 5.10 | Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy. ( Brown, MA; Buddle, ML; Davis, GK; Farrell, T, 2002) |
| "To investigate the changes of coagulation and fibrinolysis status in patients with essential hypertension (EH) and observe the therapeutic effect of sustained-release nifedipine." | 5.10 | [Coagulative and fibrinolytic changes in patients with essential hypertension and the effect of sustained-release nifedipine]. ( Chi, DS; Ge, B; Hong, XS; Jin, FX; Su, YW; Wu, BM; Yang, SG; Yu, RS, 2002) |
| "We evaluated insulin sensitivity in two groups of essential hypertensive subjects before and after treatment with either long-acting nifedipine (nifedipine-CR, Adalat CR tablets; Bayer Yakuhin, Osaka, Japan) (n = 10) or metoprolol (n = 9)." | 5.10 | Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension. ( Harano, Y; Kodama, K; Koyama, Y; Suzuki, M, 2002) |
| "To evaluate the effect of a calcium antagonist, nilvadipine, on cerebral blood flow and oxygen metabolism, we prospectively examined five ischaemic stroke patients, with both hypertension and chronic major cerebral artery occlusion, using positron emission tomography." | 5.10 | Effect of calcium antagonist on cerebral blood flow and oxygen metabolism in patients with hypertension and chronic major cerebral artery occlusion: a positron emission tomography study. ( Kobayashi, M; Noda, A; Ogasawara, K; Ogawa, A; Yasuda, S; Yukawa, H, 2003) |
| "ACE-I (enalapril) provided protection against the progression of renal insufficiency in patients of MPGN having hypertension with mild to moderate renal impairment." | 5.10 | Effects of angiotensin converting enzyme inhibitor on renal function in patients of membranoproliferative glomerulonephritis with mild to moderate renal insufficiency. ( Giri, S; Mahajan, SK; Sen, R; Sharma, A, 2002) |
| "To investigate the impact of treatment on cardiovascular mortality and morbidity, we assessed outcomes in patients with hypertension and diabetes who received co-amilozide or nifedipine in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension." | 5.10 | Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT). ( Brown, M; Castaigne, A; de Leeuw, P; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM; Wagener, G, 2003) |
| "Immediate preoperative reduction of DBP with intranasal nifedipine is safe in patients with well-controlled arterial hypertension but they presented with severe to very severe hypertension for patients in the OR." | 5.10 | The dilemma of immediate preoperative hypertension: to treat and operate, or to postpone surgery? ( Brill, S; Gurman, GM; Klein, M; Ovadia, L; Rozentsveig, V; Schily, M; Szendro, G; Tarnopolski, A; Weksler, N, 2003) |
| "To compare the effectiveness, safety and tolerability of once-daily nifedipine and amlodipine treatment in patients with mild-to-moderate essential hypertension." | 5.10 | Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine. ( Caglar, N; Canberk, A; Deger, N; Demirtas, M; Dortlemez, H; Kes, S; Kiliccioglu, B; Kozan, O; Ovunc, K; Turkoglu, C, 2003) |
| "This study aimed to compare the effects of two long-acting dihydropyridine calcium channel blockers (CCBs) with different pharmacologic properties, lercanidipine and nifedipine Gastro-Intestinal Therapeutic System (GITS), in the chronic treatment of essential hypertension." | 5.10 | Differential effects of lercanidipine and nifedipine GITS on plasma norepinephrine in chronic treatment of hypertension. ( Corradi, L; Derosa, G; Fogari, R; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A, 2003) |
| " Patients with essential hypertension were randomly assigned to receive either amlodipine, cilnidipine or nifedipine CR (which does not block N-type calcium channels) for 6 months." | 5.10 | Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension. ( Shigematsu, M; Takami, T, 2003) |
| "To compare efficacy and safety of nifedipin-retard (cordaflex-retard, Egis, Hungary) used in monotherapy and in combination with metoprolol (egilok, Egis, Hungary) in patients with arterial hypertension (AH)." | 5.10 | [Assessment of the efficacy and tolerance of delayed-action nifedipine as the monotherapy or in combination with metoprolol in patients with arterial hypertension]. ( Andreeva, GF; Dmitrieva, NA; Gorbunov, VM; Isaĭkina, OIu; Martsevich, SIu, 2003) |
| "The International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT) showed, by means of office blood pressure measurements, that long-term treatment with nifedipine GITS is as effective as diuretics in preventing cardiovascular and cerebrovascular complications." | 5.10 | Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Mancia, G; Omboni, S; Parati, G, 2002) |
| "The objective of this study was to compare the safety and efficacy of nifedipine in two different formulations (osmotic pump and slow release microgranules) in patients with essential hypertension." | 5.10 | Efficacy and safety of two different formulations of nifedipine (GITS) vs. slow release microgranules in patients with mild and moderate hypertension. ( Aroca, G; Asa, G; Botero, R; González, M, 2002) |
| "To evaluate the appropriate dosing of amlodipine when converting patients from nifedipine extended-release (nifedipine ER) to amlodipine in the treatment of hypertension." | 5.09 | Evaluation of amlodipine dosing for conversion of nifedipine extended-release to amlodipine in the treatment of hypertension. ( Enlow, AM; Halverson, VJ; Kilpatrick, DM; Lower, DL; Montopoli, G; Yamreudeewong, W, 1999) |
| "In order to study the effects of calcium-blocking therapy on cardiovascular homeostasis in elderly subjects with isolated systolic hypertension, we performed a randomised double-blind placebo-controlled crossover study of 6 weeks therapy with modified-release nifedipine or placebo." | 5.09 | Baroreflex sensitivity changes with calcium antagonist therapy in elderly subjects with isolated systolic hypertension. ( James, MA; Panerai, RB; Potter, JF; Rakicka, H, 1999) |
| "The aim of this study was to evaluate the effect of trandolapril, an angiotensin converting enzyme inhibitor, on blood pressure, forearm blood flow and insulin sensitivity in comparison with nifedipine gastrointestinal therapeutic system." | 5.09 | Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS). ( Capaldo, B; Carretta, R; Fabris, F; Ferrara, LA; Galletti, F; Glorioso, N; Mancini, M; Semplicini, A; Strazzullo, P, 1999) |
| "002; multivariate analysis of variance), with 7 significant univariate treatment effects, all favoring COER-verapamil, being noted-pedal edema, polyuria, rapid heart beat or palpitations, hives, muscle cramps, abdominal cramps, and headaches." | 5.09 | Physical Symptoms Distress Index: a sensitive tool to evaluate the impact of pharmacological agents on quality of life. ( Anderson, RB; Hollenberg, NK; Williams, GH, 1999) |
| "To evaluate the effects of cilnidipine (CNP), L- and N-type calcium channel blocker and nilvadipine (NVP) on 24-h urinary epinephrine (U-EP), norepinephrine (U-NE), dopamine (U-DA) and C-peptide (U-CPR) in patients associated with hypertension and non-insulin-dependent diabetes mellitus (HT-NIDDM), a randomized crossover study was performed with 35 HT-NIDDM patients." | 5.09 | Cilnidipine, the N- and L-type calcium channel antagonist, reduced on 24-h urinary catecholamines and C-peptide in hypertensive non-insulin-dependent diabetes mellitus. ( Hattori, Y; Irie, M; Takeda, S; Ueshiba, H, 1999) |
| "The objective of the present study is to compare the effectiveness of transdermal glyceryl-trinitrate versus oral nifedipine in lowering blood pressure in patients affected by pregnancy-induced hypertension (PIH)." | 5.09 | 24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine. ( Facchinetti, F; Menghini, S; Neri, I; Romanini, C; Valensise, H; Volpe, A, 1999) |
| "We sought to compare the efficacies of oral nifedipine and intravenous labetalol in the acute management of hypertensive emergencies of pregnancy." | 5.09 | A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy. ( Chauhan, SP; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "Our purpose was to compare the hemodynamic effects of orally administered nifedipine and intravenously administered labetalol in preeclamptic hypertensive emergencies." | 5.09 | A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies. ( Chauhan, SP; Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1999) |
| "Four hundred seventy-five patients with angina pectoris were randomized to double-blind treatment with PPR (physiological pattern release) verapamil hydrochloride, amlodipine besylate, amlodipineatenolol combination, or placebo." | 5.09 | Medical therapy, symptoms, and the distress the cause: relation to quality of life in patients with angina pectoris and/or hypertension. ( Anderson, R; Hollenberg, NK; Williams, GH, 2000) |
| "To determine whether nifedipine or prazosin is the more appropriate second-line antihypertensive agent in pregnancy." | 5.09 | Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial. ( Hall, DR; Odendaal, HJ; Smith, M; Steyn, DW, 2000) |
| "The safety of use of the calcium channel blocker nifedipine in pregnancy as it affects child development has not been well evaluated." | 5.09 | Nifedipine administered in pregnancy: effect on the development of children at 18 months. ( Bortolus, R; Chatenoud, L; Parazzini, F; Ricci, E, 2000) |
| "With the aim of evaluating the effects on blood pressure, platelet function and insulin sensitivity of the dihydropiridines lacidipine and nifedipine GITS, a parallel double-blind study was carried out in a group of 20 patients with mild to moderate essential hypertension." | 5.09 | Effect of lacidipine and nifedipine GITS on platelet function in patients with essential hypertension. ( Armas-Hernández, MJ; Armas-Padilla, MC; Carvajal, AR; Castillo-Moreno, A; Hernández-Hernández, R; Pacheco, B; Velasco, M, 2000) |
| " We compared the effects of the calcium-channel blocker nifedipine once daily with the diuretic combination co-amilozide on cardiovascular mortality and morbidity in high-risk patients with hypertension." | 5.09 | Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Brown, MJ; Castaigne, A; de Leeuw, PW; Mancia, G; Palmer, CR; Rosenthal, T; Ruilope, LM, 2000) |
| " The second aim was to determine whether there is a relationship between systolic blood pressure (SBP) and physical activity in patients with hypertension when treating with a short-acting (nifedipine) or long-acting (benidipine) calcium channel blocker." | 5.09 | Effects of short- and long-acting calcium channel blockers on the relationship between blood pressure and physical activity. ( Kakinoki, S; Kitabatake, A; Nomura, A; Takechi, S, 2001) |
| "This double-blind, parallel group study compared the effect of nifedipine gastrointestinal transport system (GITS) (L-type CCB) versus mibefradil (T-type CCB) on ANS function in patients with mild-moderate essential hypertension." | 5.09 | Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension. ( Esler, MD; Kamen, PW; Krum, H; Lim, S; Pellizzer, AM, 2001) |
| "This study was undertaken to determine if adult patients with mild to moderate essential hypertension whose blood pressure had been controlled for > or = 3 months with nifedipine GITS 30 mg could be successfully switched to a 20-mg daily dose with continued antihypertensive efficacy." | 5.09 | Blood pressure control in patients with mild to moderate essential hypertension switched from nifedipine gastrointestinal therapeutic system (GITS) 30 mg to nifedipine GITS 20 mg. ( Toal, CB, 2001) |
| "The objective of this study was to compare the long-term efficacy and safety of 6 months' treatment with barnidipine and hydrochlorothiazide (HCTZ) as monotherapy in patients aged > or = 75 years with mild to moderate essential hypertension." | 5.09 | Treatment of hypertension in the very old. ( Otterstad, JE; Ruilope, LM, 2000) |
| " The study was designed as a side arm of INSIGHT (International Nifedipine Study: Intervention as Goal for Hypertension Therapy), aimed to show the efficacy of nifedipine once daily versus co-amilozide (hydrochlorothiazide 25 mg, amiloride 2." | 5.09 | Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics. ( Motro, M; Shemesh, J, 2001) |
| "This study, ancillary to the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT), involved nifedipine 30 mg or co-amilozide (hydrochlorothiazide 25 mg and amiloride 2." | 5.09 | Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes. ( Gariépy, J; Levenson, J; Moyse, D; Simon, A, 2001) |
| "Candesartan, an AT(1) receptor antagonist, has been reported to have no association with persistent cough in subjects with hypertension, but there has been no study on the safety of its administration to hypertensive patients with symptomatic asthma." | 5.09 | Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma. ( Abe, S; Hashimoto, M; Oashi, K; Saikai, T; Suzuki, K; Tanaka, H; Tanaka, S; Teramoto, S, 2001) |
| "One hundred fifty-four renal transplant recipients presenting with hypertension (diastolic BP> or =95 mmHg) during the first 3 weeks after transplantation were randomized to receive double-blind 30 mg nifedipine or 10 mg lisinopril once daily." | 5.09 | Reduction of left ventricular mass by lisinopril and nifedipine in hypertensive renal transplant recipients: a prospective randomized double-blind study. ( Bjerkely, BL; Bryde, P; Fauchald, P; Foss, A; Hartmann, A; Holdaas, H; Ihlen, H; Midtvedt, K, 2001) |
| "The effect of quinapril and nifedipine on platelet aggregation, vascular endothelial function and coagulation system activity, was compared in a parallel-group, investigator-blind study carried out on patients with mild to moderate hypertension but no other diseases or receiving medication which might affect platelet function, vascular endothelium or coagulation." | 5.09 | A single (investigator)-blind randomised control trial comparing the effects of quinapril and nifedipine on platelet function in patients with mild to moderate hypertension. ( Bareford, D; Beevers, DG; Islim, IF, 2001) |
| "In this 1-year clinical study, we compared the efficacy and tolerability of amlodipine and nifedipine retard in 64 Chinese Type 2 diabetic patients with hypertension." | 5.09 | Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial. ( Chan, CH; Chan, HC; Ko, GT, 2001) |
| "In patients with chronic renal failure and hypertension due to primary renal disease, fosinopril significantly differed from nifedipine GITS by its capacity to slow the progressive decay in renal function." | 5.09 | A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease. ( Aljama, P; Aranda, P; Diez, J; Marin, R; Ruilope, LM; Segura, J, 2001) |
| "The combination of losartan and low-dose diuretics effectively treated hypertension in elderly patients while minimizing the metabolic consequences of diuretic therapy." | 5.09 | Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker. ( Kohno, M; Masugata, H; Ohmori, K; Ohnishi, K; Takagi, Y; Wada, Y; Yukiiri, K, 2001) |
| "The main purpose of this study was to compare efficacy, tolerability and influence on quality of life (QOL) of nifedipine gastrointestinal therapeutic system (NI) 30-60 mg once a day vs amlodipine (AM) 5-10 mg once a day in elderly patients with mild-moderate hypertension." | 5.09 | Efficacy, tolerability and influence on "quality of life" of nifedipine GITS versus amlodipine in elderly patients with mild-moderate hypertension. ( Boari, L; De Dominicis, E; Giusti, C; Kilama, MO; Marchesi, M; Marelli, G; Mattarei, M; Mos, L; Novo, S; Pessina, AC; Pirrelli, A; Santini, M; Santonastaso, M; Semeraro, S; Uslenghi, E, 2001) |
| " A single centre, prospective, randomised, double-blinded, comparative study to address the efficacy of controlled release nifedipine or lisinopril in the treatment of hypertension (diastolic blood pressure > or =95 mmHg) in cyclosporin (CsA)-treated renal transplant recipients was performed." | 5.09 | Efficacy of nifedipine or lisinopril in the treatment of hypertension after renal transplantation: a double-blind randomised comparative trial. ( Fauchald, P; Hartmann, A; Holdaas, H; Midtvedt, K, 2001) |
| "A total of 154 renal transplant patients presenting with hypertension (diastolic blood pressure >or=95 mmHg) during the first 3 weeks after transplantation were randomised to receive double-blind nifedipine 30 mg or lisinopril 10 mg once daily." | 5.09 | Sustained improvement of renal graft function for two years in hypertensive renal transplant recipients treated with nifedipine as compared to lisinopril. ( Fauchald, P; Foss, A; Hartmann, A; Holdaas, H; Midtvedt, K; Nordal, KP; Rootwelt, K, 2001) |
| "To determine the efficacy of Nifedipine on postpartum blood Loss in patients with Pregnancy Induced Hypertension (PIH)." | 5.09 | [The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension]. ( Liu, Y; Yang, X, 2000) |
| "To examine the effect of perindopril and nifedipine on renal function in patients with essential hypertension (EH)." | 5.09 | [Greater reduction of urinary albumin excretion in hypertensive patients with perindopril than nifedipine]. ( Chen, D; Lin, J; Wu, K, 1999) |
| "The purpose of the study was to compare the effect of treatment with an angiotensin converting enzyme inhibitor (Lisinopril, MSD) or calcium blocker (Nifedipine retard, MSD) treatment during three months on blood pressure (measured with sphygmomanometric method and ambulatory blood pressure monitoring--ABPM) and urinary albumin excretion in essential hypertension class I acc." | 5.08 | [Comparison of treatment effects with an angiotensin converting enzyme inhibitor--lisinopril and a calcium blocker--nifedipine retard on urinary albumin excretion in patients with non-complicated essential hypertension]. ( Celibała, R; Czekalski, S; Widecka, K, 1995) |
| "Patients with controlled hypertension (diastolic blood pressure less than 90 mmHg) on nifedipine-PA 10 mg (n = 74) or 20 mg (n = 99) bid were enrolled into an open label study consisting of six weeks of previous nifedipine-PA followed by six weeks of nifedipine-GITS therapy." | 5.08 | Comparative efficacy of two long-acting formulations of nifedipine in the treatment of hypertension. The Switch Study Investigators. ( Myers, MG; Toal, CB, 1995) |
| "A multicenter, controlled, open, randomized trial of antihypertensive and life quality (LQ) effects of monotherapy with captopril vs propranolol, hydrochlorothiazide and nifedipine included 345 males aged 35-60 years with mild and moderate hypertension." | 5.08 | [The effect of long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents on the quality of life in patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working ( Broer, M; Duda, SG; Filatova, NP; Metelitsa, VI; Mukhamedzhanova, GF; Ostrovskaia, TP; Siegrist, J; Vygodin, VA, 1995) |
| "To examine the factors that determine the blood pressure response to enalapril and nifedipine monotherapy in the treatment of hypertension associated with non-insulin-dependent diabetes mellitus (NIDDM)." | 5.08 | Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM. ( Chan, JC; Cheung, CK; Cockram, CS; Law, LK; Nicholls, MG; Swaminathan, R, 1995) |
| " In nine hypertensive patients with enalapril-induced cough the effect of altering the dose of enalapril on subjective cough and the cough response to inhaled capsaicin was examined in a random single-blind balanced cross-over study." | 5.08 | Effect of dose adjustment on enalapril-induced cough and the response to inhaled capsaicin. ( Foster, G; Higgins, KS; Jackson, PR; Ramsay, LE; Yeo, WW, 1995) |
| "To examine the central hemodynamic and blood gas responses to sublingual captopril and nifedipine administration in patients with arterial hypertension after abdominal aortic surgery." | 5.08 | Invasive hemodynamic evaluation of sublingual captopril and nifedipine in patients with arterial hypertension after abdominal aortic surgery. ( Degaute, JP; Leeman, M, 1995) |
| "To evaluate the metabolic effects of two anti-hypertensive agents with different actions, nifedipine 20 mg twice daily and furosemide 60 mg twice daily, 23 patients with untreated essential hypertension performed a double-blind, cross-over study in treatment periods of 5 months." | 5.08 | Metabolic effects of anti-hypertensive treatment with nifedipine or furosemide: a double-blind, cross-over study. ( Berne, C; Lind, L; Lithell, H; Pollare, T, 1995) |
| "Possible drug interactions between the two calcium channel blockers nimodipine and nifedipine were investigated in 12 elderly patients with stable mild to moderate hypertension." | 5.08 | The influence of nimodipine on hemodynamic parameters and peak and trough plasma concentrations of nifedipine chronically administered to elderly hypertensive patients. ( Breuel, HP; Heine, PR; Kuhlmann, J; Mück, W; Niklaus, H; Schmage, N, 1995) |
| "Evaluation of the efficacy and tolerability of nifedipine oros in patients with mild to moderate essential hypertension without major target organ damage and the anti-hypertensive effect along the 24 hours." | 5.08 | [Multicenter National Study for the evaluation of the efficacy and tolerance of nifedipine oral release osmotic system in mild to moderate hypertension]. ( Amodeo, C; Ayoub, JC; Brandão, AP; Chaves, H; de Andradre, J; Giorge, DM; Lima Júnior, E; Mion Júnior, D; Nobre, F; Ribeiro, JM, 1995) |
| "To evaluate the influence of non-steroidal anti-inflammatory drugs (NSAIDs; aspirin and indomethacin) on the renal and antihypertensive effects of enalapril and nifedipine gastrointestinal therapeutic system (GITS) in patients with essential hypertension." | 5.08 | Influence of non-steroidal anti-inflammatory drugs on renal function and 24h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients. ( Andrade, P; Bernardo, F; Boaventura, I; Brandão, F; Camões, I; Cerqueira-Gomes, M; Gama, G; Nunes, JP; Polónia, J, 1995) |
| "The purposes of this study were to compare the efficacy of sublingual nifedipine with intravenous hydrallazine in the control of acute hypertension of pregnancy and to make a preliminary assessment whether sublingual nifedipine could be recommended for use by midwives faced with severe hypertension in pregnancy in a rural setting." | 5.08 | Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice. ( Jegasothy, R; Paranthaman, S, 1996) |
| " The medication of 39 patients with hypertension was changed from once-daily diltiazem hydrochloride (Cardizem CD) or nifedipine (Procardia XL) to felodipine (Plendil)." | 5.08 | Felodipine as an alternative to more expensive calcium antagonists in mild to moderate hypertension. ( Horwhat, JD; Landry, FJ; Pinski, L; Tomich, D, 1996) |
| " In a prospective randomized study, 14 patients with NIDDM, hypertension, proteinuria, and renal insufficiency were given either isradipine (n = 7) or nifedipine XL (n = 7) for 6 months." | 5.08 | Effects of dihydropyridine calcium antagonists on albuminuria in patients with diabetes. ( Abbott, K; Bakris, GL; Smith, A, 1996) |
| "The effect of nifedipine in the treatment of hypertensive venous leg ulcers was studied on 30 outpatients in a double-blind placebo-controlled trail over a period of 2 months." | 5.08 | Treatment of hypertensive venous leg ulcers with nifedipine. ( Nikolova, K, 1995) |
| "According to a double-blind, randomized, crossover design, 58 patients with mild-to-moderate essential hypertension, after 1 month placebo washout, received 30 mg/day nifedipine gastrointestinal therapeutic system, 20 mg nifedipine retard twice a day and the corresponding placebos for 1 month." | 5.08 | Trough:peak ratio of nifedipine gastrointestinal therapeutic system and nifedipine retard in essential hypertensive patients: an Italian multicentre study. ( Ambrosoli, S; Buoninconti, R; Caiazza, A; del Prato, C; Gandolfi, E; Kilama, MO; nello Ceccarelli, C; Saba, G; Salvetti, A; Spadari, G; Taddei, S; Virdis, A, 1996) |
| " Thus, a group of 76 consecutive patients with mild-to-moderate hypertension and chronic obstructive pulmonary disease (COPD) were selected to participate in a clinical antihypertensive trial to define the roles of lisinopril, nifedipine and conventional therapy, and their impact on the renin-antiotensin system (RAS)." | 5.08 | Comparisons of long-term effects of lisinopril vs nifedipine vs conventional therapy in the treatment of mild-to-moderate hypertension in patients with chronic obstructive pulmonary disease. ( Chiang, HT; Lee, D; Lin, M; Yang, YF, 1996) |
| " The aim of the study was to assess effects of sublingual 10 mg nifedipine (n = 15) or 25 mg captopril (n = 13) on HRV in consecutive patients admitted to hospital due to severe hypertension." | 5.08 | Nifedipine and captopril exert divergent effects on heart rate variability in patients with acute episodes of hypertension. ( Ceremuzynski, L; Kulakowski, P; Wolk, R, 1996) |
| "A single-blind trial was conducted under the direction of the Shanghai Institute of Hypertension in 1632 subjects aged 60-79 years alternatively allocated to either nifedipine or placebo after a 4-week placebo run-in period between 1987 and 1990 with mean follow-up of 30 months." | 5.08 | Shanghai trial of nifedipine in the elderly (STONE). ( Ghadirian, P; Gong, L; Hamet, P; Kong, D; LeLorier, J; Pagé, V; Zhang, W; Zhu, J; Zhu, Y, 1996) |
| "To compare the efficacy and tolerance of felodipine-ER and nifedipine OROS, both once daily, in the treatment of mild-to-moderate uncomplicated arterial hypertension (AH)." | 5.08 | [Multicenter comparative study of felodipine-ER and nifedipine-OROS in the treatment of mild-to-moderate arterial hypertension]. ( Armaganijan, D; Batlouni, M; Castro, I; Chaves Junior, Hde C; Leite Luna, R; Nobre, F; Pereira da Cunha, C; Silveira Sbissa, A, 1996) |
| "26 patients with hypertension while on hemodialysis or continuous ambulatory peritoneal dialysis for end-stage renal diseases were treated first with enalapril and then changed to metoprolol." | 5.08 | A comparison of the effect of enalapril and metoprolol on renal function, potassium balance, lipid profile, cardiac function, exercise tolerance and quality of life in hypertensive dialysis patients. ( Lai, KN; Lam, WK; Li, KT; Lui, SF; Nicholls, MG; Wong, KC; Woo, KS, 1995) |
| " In this double-blind forced titration study design we compared the effects of mibefradil 50, 100, and 150 mg and nifedipine GITS 30, 60, and 90 mg monotherapies or combined with lisinopril 20 mg in 71 moderate to severe hypertensives (59 men and 12 women) with confirmed ambulatory hypertension." | 5.08 | The antihypertensive efficacy of the novel calcium antagonist mibefradil in comparison with nifedipine GITS in moderate to severe hypertensives with ambulatory hypertension. ( Archambault, F; Dalle Ave, S; Lacourcière, Y; Lefebvre, J; Lindberg, E; Poirier, L; Ward, C, 1997) |
| "Both felodipine ER and nifedipine Retard are effective "add-on' drugs in patients with monotherapy-resistant hypertension." | 5.08 | Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring. ( Breed, JG; Dees, A; Kremer Hovinga, T; Meems, L; Puister, SM; Verstappen, VM, 1997) |
| " Angiotensin converting enzyme inhibitors (ACE-I) significantly retarded the development of end-stage renal failure compared to antihypertensives other than ACE-I (mostly nifedipine), and the effect was evident particularly in patients with proteinuria below the median (2." | 5.08 | Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients. ( Babazono, T; Hirayama, M; Ishii, A; Omori, Y; Takahashi, C; Takeda, M; Tomonaga, O; Ujihara, U; Yokoyama, H, 1997) |
| "To investigate the 24-hour efficacy of nilvadipine (8 and 16 mg)in patients with mild to moderate essential hypertension, a double-blind, randomized, placebo-controlled, multicenter study with 3 parallel medication groups (placebo, 8, and 16 mg nilvadipine) was performed." | 5.08 | Nilvadipine in hypertension--experience in ambulatory treatment. ( Burkardt, I; Hoffmann, A; Kraul, H, 1997) |
| "The potential role of endothelin-1 (ET-1) in essential hypertension in humans is still subject to debate." | 5.08 | Endothelin-1-induced vasopressor responses in essential hypertension. ( Kaasjager, KA; Koomans, HA; Rabelink, TJ, 1997) |
| "Patients with nifedipine-induced gingival hyperplasia (GH) often require continued calcium channel blocker therapy." | 5.08 | Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine. ( Bednarczyk, EM; Bissada, NF; Carlson, M; Sheehan, H; Westbrook, P, 1997) |
| "In 102 cases of severe hypertension (DBP > or = 115 mm Hg), with or without acute complications, efficacy and safety of SL Nifedipine 10 mg (NIF), SL Captopril 25 mg (CAP), IV Metoprolol 15 mg (MET) and SL NIF + IV MET were studied in an inpatient trial." | 5.08 | Nifedipine, captopril, metoprolol and nifedipine with metoprolol in hypertensive crisis in non-intensive care setting. ( Bhatt, AD; Dadkar, VN; Kapadia, NM; Karnik, ND; Khokhani, RC; Trivedi, TH; Vaidya, AB, 1996) |
| "The safety and tolerability of mibefradil, a selective T-type calcium channel antagonist, were evaluated in 3,430 patients with essential hypertension and chronic stable angina pectoris treated in 15 double-blind placebo and active-controlled clinical trials and 2 open-label, long-term safety studies." | 5.08 | Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist. ( Charlon, V; Kobrin, I; Lindberg, E; Pordy, R, 1997) |
| "Because blood viscosity is significantly raised in patients with essential hypertension (EH), the hemorheological effects of a 4-month chronic treatment with the calcium antagonist nilvadipine (FK 235, 5-isopropyl-3-methyl-2-cyano-1,4-dihydro-6-methyl-4- (m-nitrophenyl)-3,5-pyridinedicarboxylate, CAS 75530-68-6) on elevated blood viscosity was investigated prospectively in patients with EH, and compared with those in normotensive individuals of similar age." | 5.08 | Chronic hemorheological effects of the calcium antagonist nilvadipine in essential hypertension. ( Izumi, Y; Kitadai, M; Satoh, K; Takahashi, T; Tsuda, Y, 1997) |
| "Quality of life with the selective beta1-blocker bisoprolol and the calcium channel blocker nifedipine as a retard formulation was compared in patients with essential hypertension." | 5.08 | Quality of life comparison between bisoprolol and nifedipine retard in hypertension. ( de Hoon, JN; Van Bortel, LM; van de Ven, LL; Vanmolkot, FH, 1997) |
| " This study assessed the efficacy and safety of nifedipine GITS (oral release osmotic system) as monotherapy, in addition to the effects on left ventricular hypertrophy, after a long term follow-up (one year)." | 5.08 | [Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle]. ( Arocha, I; Arreaza, MR; Bustillo, N; Corral, JL; García, P; López, NC; Perozo, M, 1997) |
| "The purpose of the study was to compare the antianginal and hypotensive efficacy and tolerability of 8 weeks of treatment with amlodipine taken once daily and nifedipine taken twice daily in patients with stable exertional angina pectoris and mild-to-moderate hypertension." | 5.08 | [Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension]. ( Hlawaty, M; Kubler, G; Negrusz-Kawecka, M; Olszowska, M; Salamon, P; Tracz, W; Witkowska, M, 1997) |
| "This study compared the effects of 1 year of monotherapy with a calcium-channel antagonist (nilvadipine; NIL), an angiotensin-converting enzyme (ACE) inhibitor (temocapril; TEM), or a new vasodilator (cadralazine; CAD) on left ventricular (LV) hypertrophy in essential hypertension." | 5.08 | The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors. ( Inoue, H; Oh-hashi, S; Takata, M; Tomita, S; Ueno, H; Yasumoto, K, 1997) |
| "Nifedipine GITS was superior to enalapril in controlling ambulatory blood pressure, but they were equivalent in reducing proteinuria (37%)." | 5.08 | Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt. ( DeQuattro, V; Lee, DP, 1997) |
| "In a randomized parallel-group placebo-controlled study, we compared the short-term hypotensive efficacy and the safety of a single administration of nifedipine-retard (20-mg tablets) with that of two administrations 6 h apart of nifedipine capsules (10 mg) in 10 and 11 black patients, respectively, with acute severe hypertension." | 5.08 | Nifedipine-retard versus nifedipine-capsules for the therapy of hypertensive crisis in black patients. ( Damasceno, A; Patel, S; Polónia, J; Sevene, E, 1998) |
| "MIBEFRADIL IN THE TREATMENT OF HYPERTENSION: The antihypertensive efficacy of mibefradil, a new selective transient (T)-channel calcium antagonist, was studied in eight randomized, double-blind, parallel-design trials: four placebo-controlled and four active drug-controlled versus other calcium antagonists." | 5.08 | Differential properties of mibefradil in hypertension and angina. ( Kobrin, I, 1997) |
| "To compare the effect of four drug groups on the ambulatory circadian blood pressure (BP) pattern, amiloride hydrochlorothiazide, atenolol, nifedipine, and perindopril (5/50 mg/d, 100 mg/d, 40 mg/d, and 4 mg/d respectively, for 14 days) were alternated in each of 20 essential hypertension patients." | 5.08 | Effect of hypotensive drugs on the circadian blood pressure pattern in essential hypertension: a comparative study. ( Moulopoulos, S; Stamatelopoulos, S; Zakopoulos, N, 1997) |
| "Administration of amlodipine did not induce an increase in sympathetic nerve activity in essential hypertensive patients during the chronic period, suggesting that beneficial effects on essential hypertension can be expected after its long-term administration." | 5.08 | Evaluation of changes in sympathetic nerve activity and heart rate in essential hypertensive patients induced by amlodipine and nifedipine. ( Fujimoto, Y; Hamada, T; Hisatome, I; Kaneda, T; Kinugawa, T; Ohtahara, A; Shigemasa, C; Watanabe, M; Yoshida, A, 1998) |
| "The antihypertensive efficacy and safety of mibefradil and nifedipine SR were compared in 143 patients with chronic renal failure and mild-to-moderate hypertension in a multicenter, double-blind, randomized, parallel-design study." | 5.08 | A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension. ( Bailey, R; Huysmans, FT; Kobrin, I; Mion Júnior, D; Robson, RA; Villa, G; Woittiez, AJ, 1998) |
| " The compliance, efficacy, and safety of amlodipine and nifedipine slow-release (SR) were compared in patients with mild-to-moderate essential hypertension recruited among 24 centers in France." | 5.08 | Compliance and antihypertensive efficacy of amlodipine compared with nifedipine slow-release. ( Bernaud, C; Carré, A; Charpentier, JC; Hotton, JM; Lequeuche, B; Mounier-Vehier, C, 1998) |
| "To evaluate the 24 h antihypertensive efficacy and duration of action of felodipine extended release (ER) in comparison with two other long acting dihydropyridine calcium antagonists, amlodipine and nifedipine gastrointestinal therapeutic system (GITS), in patients with mild to moderate essential hypertension substantiated by ambulatory blood pressure (BP) monitoring." | 5.08 | Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study. ( Archambault, F; Jewell, D; Lacourcière, Y; Lefebvre, J; Poirier, L; Reed, CV, 1998) |
| "Since both agents were equally effective in reducing both SBP and DBP and reserpine is much cheaper than nifedipine, it is recommended that for a developing country like Zimbabwe, the combination of HCT and reserpine at the above doses should be used as the first step to treat mild to moderate hypertension without evidence of end organ damage." | 5.08 | A randomised crossover comparison of reserpine and sustained-release nifedipine in hypertension. ( Manyemba, J, 1997) |
| " The purpose of this study was to assess the risk ratio for cancer mortality associated with nifedipine in a large population of patients post-myocardial infarction." | 5.08 | Nifedipine and cancer mortality: ten-year follow-up of 2607 patients after acute myocardial infarction. ( Behar, S; Boyko, V; Goldbourt, U; Jonas, M; Mandelzweig, L; Reicher-Reiss, H, 1998) |
| " In order to assess the haemodynamic profile of the antihypertensive effect of barnidipine, a randomized, double-blind study of barnidipine vs nitrendipine was performed in 24 patients with mild to moderate essential hypertension." | 5.08 | Distinct vasodilation, without reflex neurohormonal activation, induced by barnidipine in hypertensive patients. ( Argenziano, L; De Luca, N; Iovino, G; Izzo, R; Morisco, C; Parrella, L; Trimarco, B, 1998) |
| "To compare the effect of routine treatment with the calcium channel blocker nifedipine in mild to moderate hypertension in pregnancy." | 5.08 | Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza. ( , 1998) |
| ") infusion of two dihydropyridine calcium channel blockers (either nifedipine or felodipine) in 122 patients, of whom 63 were diagnosed as hypertensive emergencies and 59 as hypertensive crisis, who had not reacted adequately (diastolic blood pressure <115 mmHg) to 5 mg of nifedipine PO." | 5.08 | A comparison of the antihypertensive efficacy and safety of felodipine IV and nifedipine IV in patients with hypertensive crisis or emergency not responding to oral nifedipine. ( Bohm, R; Erley, CM; Koch, HH; Nast, HP; Risler, T; Stein, G; Wetzchewald, D, 1998) |
| "We compared the effects of cilnidipine and nifedipine retard on 24-h blood pressure (BP), heart rate (HR), and autonomic nerve activity in patients with essential hypertension." | 5.08 | Comparison of 24-hour blood pressure, heart rate, and autonomic nerve activity in hypertensive patients treated with cilnidipine or nifedipine retard. ( Ishimitsu, T; Kawano, Y; Matsuoka, H; Minami, J; Numabe, A, 1998) |
| "To compare the acute and chronic effects of nifedipine retard (NPA), nifedipine gastrointestinal therapeutic system (NGITS) and amlodipine at trough and peak plasma concentrations of drug on blood pressure and heart rate, and on plasma norepinephrine and epinephrine levels in patients with mild-to-moderate hypertension (diastolic blood pressure 95-115 mmHg)." | 5.08 | Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients. ( Cartier, P; de Champlain, J; Karas, M; Larochelle, P; Nadeau, R; Nguyen, P; Toal, CB; Wistaff, R, 1998) |
| "To assess the effect of 1-year treatment with rilmenidine, an oxazoline compound that exerts its antihypertensive effects through binding to imidazoline receptors in the brainstem, on left ventricular hypertrophy (LVH) secondary to essential, mild-to-moderate hypertension [supine diastolic blood pressure (DBP)95-115 mmHg]." | 5.08 | Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study. ( Balazovjech, I; Dubai, G; Dvorak, I; Januszewicz, W; Krupa-Wojciechowska, B; Kubasik, A; Kuch-Wocial, A; Polak, G; Sadowski, Z; Simon, K; Stejfa, M; Szwed, H, 1998) |
| "The aim of this study was to evaluate the effect of the calcium antagonist Nifedipine GITS in a double-blind, randomized comparison with the diuretic hydrochlorothiazide (HCTZ) on reduction of left ventricular (LV) mass and minimal vascular resistance in a group of essential hypertensives with left ventricular hypertrophy (LVH)." | 5.08 | Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients. ( Agabiti-Rosei, E; Corbellini, C; Monteduro, C; Muiesan, ML; Rizzoni, D; Salvetti, M; Zulli, R, 1998) |
| " Among these trials, the International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT) is of special interest because it is the first study to address, in a prospective fashion, the prognostic influence of antihypertensive treatment (nifedipine GITS vs a combined thiazide and potassium-sparing diuretic) in hypertensive patients with concomitant risk factors such as hypercholesterolemia, cigarette smoking, diabetes, and left ventricular hypertrophy." | 5.08 | The International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT) trial. ( Grassi, G; Mancia, G, 1998) |
| "Mibefradil is a calcium antagonist approved for the treatment of hypertension and chronic stable angina pectoris." | 5.08 | Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease. ( Pordy, R; Woittiez, A, 1998) |
| "To compare the acute and chronic effects of nifedipine retard (NPA), nifedipine gastrointestinal therapeutic system (NGITS) and amlodipine at trough and peak plasma concentrations of drug on blood pressure and heart rate, and on plasma norepinephrine and epinephrine levels in patients with mild-to-moderate hypertension (diastolic blood pressure 95-115 mmHg)." | 5.08 | Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients. ( Cartier, P; de Champlain, J; Karas, M; Larochelle, P; Nadeau, R; Nguyen, P; Toal, CB; Wistaff, R, 1998) |
| " The study group comprised 43 women treated with nifedipine (30-60 mg/day) for mild to moderate hypertension for at least 1 year, and the control group comprised 42 normotensive women." | 5.08 | Abnormal sonographic endometrial findings in asymptomatic postmenopausal women: possible role of antihypertensive drugs. ( Aschkenazi, S; Ben-Refael, Z; Kaplan, B; Nitke, S; Orvieto, R; Pardo, J, 1998) |
| "To ascertain the baseline characteristics of the high-risk hypertensive patients entering the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT)." | 5.08 | Study population and treatment titration in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT). ( Brown, MJ; Castaigne, A; de Leeuw, PW; Mancia, G; Rosenthal, T; Ruilope, LM, 1998) |
| "Thirteen psoriatic patients with hypertension during the course of cyclosporin A therapy were treated for 25 months with a calcium channel blocker, sustained-release nifedipine, to study the clinical antihypertensive effects and adverse events during treatment with both drugs." | 5.08 | Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis. ( Furue, M; Koga, T; Nakayama, J, 1998) |
| "The efficacy and acceptability of 5 mg nebivolol once daily, a long-acting, vasodilating cardioselective beta blocker that additionally facilitates the L-arginine/nitric oxide system, was assessed in a double-blind, randomized trial in comparison with 20 mg nifedipine retard twice daily in patients with essential hypertension." | 5.08 | Nebivolol versus nifedipine in the treatment of essential hypertension: a double-blind, randomized, comparative trial. ( Dupont, AG; Korlipara, K; Lacourcière, Y; Marcadet, DM; Robertson, JI; Van Nueten, L; Vyssoulis, G, 1998) |
| "Ninty patients with mild to moderate essential hypertension (EH) were randomly divided into three groups and treated with Enalapril (E), Metoprolol (M) and Nifedipine (N) respectively." | 5.08 | [Effect of antihypertensive agents on plasma endothelin, nitric oxide and so on in essential hypertension]. ( Chen, S; Liu, G; Yang, T, 1997) |
| "To investigate the effect of amlodipine, nifedipine and perindopril on insulin sensitivity(IS) and blood lipid of patients with essential hypertension(EH)." | 5.08 | [The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension]. ( Chen, D; Lin, J; Wu, K, 1998) |
| "5 mg/day) on regression of left ventricular hypertrophy (LVH), an independent predictor of poor prognosis in hypertension, was compared by echocardiography to that of nifedipine (NFD, 40 mg/day), enalapril (ENL, 20 mg/day), atenolol (ATL, 100 mg/day), and hydrochlorothiazide (HCTZ, 25 mg/day) in four parallel double-blind studies in 151 hypertensive patients with a diastolic blood pressure between 95 and 120 mm Hg and a raised left ventricular mass index (LVMI) (mg/m2) (Devereux)." | 5.07 | Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study. ( Amabile, G; Bory, M; De Luca, N; Denis, B; Imbs, JL; Lahiri, A; Marchegiano, R; Raftery, EB; Senior, R; Zannad, F, 1993) |
| "The efficacy and tolerability of amlodipine (5 mg, once daily), nifedipine retard (20 mg, twice daily), and placebo were compared in a multicenter, three-way, crossover study involving 97 patients with mild-to-moderate hypertension." | 5.07 | Side effects of dihydropyridine therapy: comparison of amlodipine and nifedipine retard. ( Bremner, AD; Fell, PJ; Hosie, J; James, GV; Saul, PA; Taylor, SH, 1993) |
| "The present study was performed to investigate the efficacy and safety of the angiotensin converting enzyme (ACE) inhibitor lisinopril compared with those of the calcium channel blocker nifedipine in 293 patients with mild to moderate essential hypertension (supine diastolic blood pressure (DBP) 95-115 mmHg) in a multicentre, randomised, double-blind parallel group study after a two week single-blind placebo run-in period." | 5.07 | Lisinopril versus slow release nifedipine in patients with essential hypertension: a multicentre study. ( Kramer, HJ; Predel, HG, 1994) |
| "In a double-blind double-dummy multicenter study, patients with mild to moderate essential hypertension were randomized to receive either nifedipine (n = 416, 47." | 5.07 | Female preponderance for lisinopril-induced cough in hypertension. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1994) |
| "Nifedipine tablet in a 20 mg dose was administered orally to 44 patients with arterial hypertension." | 5.07 | Nifedipine kinetics and dynamics in hypertensive patients: a new approach. ( Akopov, SE; Grigorian, GS; Panossian, AG; Sarkissian, MA, 1994) |
| "To compare nifedipine (group 1) with methyldopa (group 2) in the management of pregnancy induced hypertension (PIH)." | 5.07 | A comparison of nifedipine with methyldopa in pregnancy induced hypertension. ( Jayawardana, J; Lekamge, N, 1994) |
| "The therapeutic efficacy of long acting diltiazem 300 mg od (Tildiem LA) was compared with sustained release nifedipine 20 mg bd and bendrofluazide 5 mg od in a multicentre study with 230 patients diagnosed with mild to moderate essential hypertension, with 77, 77 and 76 randomized to the diltiazem, nifedipine SR and bendrofluazide groups respectively." | 5.07 | A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension. ( Belgrave, GP; Hosie, J; Nasar, MA; Walters, EG, 1994) |
| "To compare the effects of nifedipine and enalapril on carbohydrate and lipoprotein metabolism in Chinese non-insulin-dependent diabetes mellitus (NIDDM) patients with hypertension." | 5.07 | The effects of enalapril and nifedipine on carbohydrate and lipid metabolism in NIDDM. ( Chan, JC; Cockram, CS; Leung, DH; Nicholls, MG; Tomlinson, B; Yeung, VT, 1994) |
| "To evaluate the antihypertensive efficacy and safety of cilazapril compared to nifedipine retard in mild to moderate hypertension." | 5.07 | [Comparative and double-blind study of the efficacy and safety of cilazapril compared to nifedipine retard in the treatment of mild and moderate arterial hypertension]. ( Athanázio-Heliodoro, RC; Franco, RJ; Marcondes, M; Martin, LC; Mion Júnior, D; Pascoal, IJ; Sampaio, M; Tinucci, T; Velasco-Cornejo, IF, 1994) |
| "The authors studied the antihypertensive effect and tolerability of a new sustained-release formulation of nifedipine 50 mg once a day, in comparison with nifedipine retard 20 mg twice a day in patients with mild or moderate primary arterial hypertension." | 5.07 | Controlled study with a new sustained-release formulation of nifedipine in essential hypertensive patients. ( Barba, G; Galletti, F; Mancini, M; Nardecchia, A; Pirrelli, A; Scagliusi, P; Strazzullo, P, 1994) |
| "Lisinopril has been compared with slow-release nifedipine in a 16-week double-blind, randomized, parallel-group study involving 102 patients with mild to moderate hypertension." | 5.07 | A comparison of lisinopril and nifedipine in the treatment of mild to moderate hypertension. A multicentre study. ( Rogstad, B, 1994) |
| "In a randomized, double blind, parallel-group, multicentre study in Norway, 97 patients with mild to moderate hypertension (mean blood pressure 159/104 mm Hg) were treated with either lisinopril 10-40 mg or nifedipine 20-80 mg and the effects on blood lipids were evaluated." | 5.07 | [Lisinopril and nifedipine have neutral effects on lipids]. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1994) |
| "Nineteen patients with essential hypertension on regular treatment with nifedipine tablets 20 mg twice daily and whose DBP was < 95 mmHg on at least two occasions two weeks apart were entered in a double-blind randomised crossover study of three weeks treatment with nifedipine coat core (new formulation) either as 30 mg one daily or as 60 mg once daily dose." | 5.07 | Double-blind crossover study of once daily nifedipine coat core in essential hypertension. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Missouris, CG; Singer, DR, 1994) |
| "Evaluation of the effects of nilvadipine on nifedipine-induced lower-leg edema." | 5.07 | [Effect of nilvadipine on nifedipine-induced edema of the lower leg. Results of a double-blind randomized comparative study]. ( Schmitt, W; Vollmuth, M, 1994) |
| " The hemodynamic responses to captopril 25 mg SL (n = 10) and to nifedipine 10 mg SL (n = 10) were studied for 2 hours in patients (mean age 66 years) with arterial hypertension (mean blood pressure, Pa > or = 115 mmHg) the day after abdominal aortic surgery." | 5.07 | [Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually]. ( Degaute, JP; Leeman, M, 1993) |
| " To investigate the effect of two different antihypertensive agents, nifedipine and enalapril, on cardiovascular reactivity and lipoprotein patterns in cigarette smokers with hypertension, 92 essential hypertensive (175 +/- 11/103 +/- 8 mm Hg) subjects were studied, who had no sign of lipidosis, and subdivided into four groups in order of smoking habit and therapy." | 5.07 | Lipids and cardiovascular reactivity changes in hypertensive cigarette smokers: enalapril versus nifedipine treatment effects. ( Cicco, G; Manzari, M; Merlo, M; Nazzaro, P; Pirrelli, A, 1994) |
| "The efficacy of lisinopril 10-40 mg once daily was compared with that of nifedipine tablets 20-40 mg twice daily in a multicentre double-blind randomized parallel group study of 16 weeks duration involving 127 patients with mild to moderate hypertension." | 5.07 | ACE inhibition versus calcium antagonism in the treatment of mild to moderate hypertension: a multicentre study. Ireland-Netherlands Lisinopril-Nifedipine Study Group. ( Clarke, RJ; Hart, W, 1993) |
| " We studied 293 patients (below 65 years of age) under treatment with either lisinopril (n = 144) or nifedipine (n = 149) for mild to moderate hypertension for 10 weeks, and with serum cholesterol above 6." | 5.07 | Effect and tolerability of combining lovastatin with nifedipine or lisinopril. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1993) |
| "This study assessed the effectivity of the association between a diuretic, chlorthalidone, and retard nifedipine in the treatment of patients above 50 years of age with Arterial Hypertension refractory to retard nifedipine." | 5.07 | [Evaluation of a combination of a diuretic and nifedipine retard for the treatment of hypertensive patients refractory to nifedipine retard]. ( Florenciano Sánchez, R; Gómez Márquez, M; Martínez López, JJ; Molina Boix, M; Ortega González, G; Rúiz López, FJ, 1993) |
| "We evaluated exercise performance in 14 patients with uncomplicated essential hypertension 1 h after the administration of a single dose of placebo, nifedipine (20 mg), captopril (50 mg), and propranolol (80 mg)." | 5.07 | Modification of exercise performance by sharp reduction of blood pressure. A study in patients with uncomplicated hypertension. ( Agostoni, PG; Alimento, M; Doria, E; Muratori, M; Riva, S; Tamborini, G, 1993) |
| "The effects of nifedipine retard and captopril on renal haemodynamic parameters have been examined in a double blind randomised cross-over trial in 10 insulin-dependent diabetic males with hypertension (systolic pressure > 150 mmHg or diastolic pressure > 90 mmHg)." | 5.07 | Renal responses to nifedipine and captopril in hypertensive insulin-dependent diabetic men: a randomized cross-over study. ( Clarke, BF; Cowan, P; Jenkins, DA; Patrick, AW, 1993) |
| " We measured lymphocyte and serum magnesium and potassium in 28 patients treated for hypertension for 6 months with nifedipine or captopril." | 5.07 | Effect of prolonged nifedipine or captopril therapy on lymphocyte magnesium and potassium levels in hypertension. ( Daly, K; Finn, J; Grimes, H; Lavin, F; Mannion, A; O'Keeffe, S, 1993) |
| "Nifedipine is an effective compound for the treatment of hypertension." | 5.07 | Double-blind comparison between nifedipine and amlodipine for the treatment of essential hypertension. ( Cappuccio, FP; Carney, C; Crane, M; MacGregor, GA; Markandu, ND; Singer, DR, 1993) |
| "55 g/day of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) on BP and serum lipids were assessed in 18 males with hypertension (WHO stage I-II)." | 5.07 | Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension. ( Eritsland, J; Hjermann, I; Hysing, J; Landmark, K; Mundal, HH; Thaulow, E, 1993) |
| "In a multicentre crossover study of 97 patients with mild hypertension, the incidence and severity of adverse effects were observed during the first 14 days of treatment with amlodipine, nifedipine retard or placebo." | 5.07 | Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard. ( Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH, 1993) |
| "The antihypertensive efficacy of single-drug therapy with nifedipine (N), prazosin (P), or acebutolol (A) and the influence of these agents on coronary risk factors including hypoglycemia, hyperuricemia, and hyperlipidemia, were studied in adolescents with hypertension." | 5.07 | [Evaluation of the efficacy and tolerance of three antihypertensive agents used as single-drug therapy, nifedipine, prazosin and acebutolol in severe, idiopathic hypertension in adolescents]. ( Cichocka, E; Januszewicz, P; Wyszynska, T, 1993) |
| "The comparative efficacy of the calcium antagonists isradipine and nifedipine in reducing left ventricular peak systolic wall tension was assessed in 25 patients with essential hypertension (20 men, 5 women; mean age: 49 years)." | 5.07 | Effect of short-term antihypertensive therapy on left ventricular wall tension. A double-blind comparison of isradipine and nifedipine. ( Burger, KJ; Griebenow, R; Müller, R; Steffen, HM; Welzel, D, 1993) |
| "The effect of three calcium entry blockers--verapamil, nifedipine and felodipine--on diuresis, natriuresis, the renin-aldosterone axis, and atrial natriuretic peptide (ANP) levels was studied in 30 previously untreated patients with mild to moderate essential hypertension." | 5.07 | The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers. ( Ezra, D; Peleg, E; Rosenthal, T; Shamiss, A, 1993) |
| "Thirty women with pregnancy-induced hypertension (PIH) scheduled for Caesarean section under general anaesthesia were studied to evaluate the efficacy of sublingual nifedipine in attenuating the pressor response to laryngoscopy and tracheal intubation." | 5.07 | Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension. ( Bala, I; Batra, YK; Gopalan, S; Kumar, N, 1993) |
| "An interim analysis of patient compliance is reported in 234 hypertension outpatients who were entered into a large-scale, open, crossover, comparative study between a new-generation calcium antagonist, amlodipine (5 mg, once daily), and nifedipine SR (20 mg, twice daily)." | 5.07 | Patient compliance and therapeutic coverage: amlodipine versus nifedipine SR in the treatment of hypertension and angina: interim results. Steering Committee and Cardiologists and General Practitioners involved in the Belgium Multicentre Study on Patient ( Detry, JM, 1994) |
| "In an open monocentric phase II study, 20 inpatients with hypertension were treated with a single daily dose of nilvadipine for 3 weeks after a 1-week placebo washout phase." | 5.07 | 24-hour blood pressure control after single daily doses of nivaldipine in patients with essential hypertension. ( Huber, HJ; Kuchlbauer, R; Lossnitzer, K; Quitzdorff, G, 1992) |
| "to compare lisinopril and nifedipine in the management of essential hypertension in 52 patients in general practice with respect to the obtaining of target diastolic blood pressure and freedom from side effects." | 5.07 | A comparative trial of lisinopril and nifedipine in mild to moderate hypertension in general practice. ( Murdoch, JC, 1992) |
| "In a Norwegian, double-blind, double-dummy multicenter study, 828 patients with mild to moderate hypertension were randomized to treatment by either lisinopril or nifedipine." | 5.07 | [Cough during treatment with angiotensin-converting enzyme inhibitors is gender related]. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1992) |
| "In a randomized, parallel, double-blind study, lisinopril (n = 412) reduced systolic and diastolic blood pressure more than nifedipine did (n = 416) after ten weeks treatment in patients (40-70 years) with mild to moderate essential hypertension." | 5.07 | [Treatment with lisinopril or nifedipine in essential hypertension. A Norwegian multicenter study of the effect, tolerance and quality of life of 828 patients]. ( Bratland, B; Dahlöf, B; Gisholt, K; Os, I; Syvertsen, JO; Tretli, S, 1992) |
| "The purpose of this placebo-control, double-blind, randomized and crossover study is to evaluate the effect of nicardipine and nifedipine in Chinese senile hypertension." | 5.07 | [Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study]. ( Chang, MS; Chen, CH; Chen, JW; Wang, SP, 1992) |
| "The safety and tolerability of carvedilol, a new antihypertensive agent with the combined pharmacological activities of beta-blockade and vasodilation, and of nifedipine were investigated in patients with essential hypertension and non-insulin-dependent (type II) diabetes mellitus." | 5.07 | Comparison of the effects of carvedilol and nifedipine in patients with essential hypertension and non-insulin-dependent diabetes mellitus. ( Adezati, L; Albergati, F; Boeri, D; Lombardo, I; Paternó, E; Semino, S; Venuti, RP; Viviani, GL, 1992) |
| "QUERY: Influence of Nilvadipine, a new calcium channel blocker on the daytime blood pressure profile and 24-hour blood pressure values in patients with mild-to-moderate hypertension." | 5.07 | [Effect of nilvadipine on diurnal blood pressure profile. Use of a new calcium channel blocker in mild to intermediate hypertension]. ( Keck, M; Quitzdorff, G, 1992) |
| "Nitrendipine (bypress) manufactured by Bayer Company in the form of 10 and 20 mg tablets and administered in a dose of 20-40 mg/day turned out an effective antihypertensive remedy in 65% of patients with arterial hypertension largely running a mild course." | 5.07 | [The efficacy of nitrendipine in patients with stable arterial hypertension. The data from a cooperative study in the USSR. The Working Group for the Cooperative Study of Nitrendipine]. ( Metelitsa, VI; Ostrovskaia, TP, 1992) |
| "To determine whether nitroglycerin is as effective as nifedipine in lowering the blood pressure in severe hypertension and hypertensive crisis, two groups of 20 patients received in random sequence either 1." | 5.07 | Comparison of nitroglycerin with nifedipine in patients with hypertensive crisis or severe hypertension. ( Bussmann, WD; Kenedi, P; Nast, HP; Rachor, N; von Mengden, HJ, 1992) |
| "To determine whether a dose of 5 mg of nifedipine would be useful in the treatment of hypertensive emergencies, we compared the acute hypotensive effects of two different doses of nifedipine, 5 mg and 10 mg, in patients with severe hypertension." | 5.07 | A comparison of the acute hypotensive effects of two different doses of nifedipine. ( Maharaj, B; van der Byl, K, 1992) |
| "In a double-blind, crossover trial 12 patients with hypertension and peripheral arterial disease were randomized to three months' treatment with captopril 25-50 mg twice daily or nifedipine SR 20-40 mg twice daily." | 5.07 | Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication. ( Breckenridge, A; Linge, K; McLoughlin, GA; Roberts, DH; Tsao, Y, 1992) |
| "The efficacy and safety of amlodipine in the long term treatment of outpatients with mild to moderate hypertension were examined in an open, non-comparative study." | 5.07 | [Effectiveness and tolerance of amlodipine in treatment of patients with mild to moderate hypertension. Results of a long-term study with a new calcium antagonist]. ( Ganzinger, U; Habeler, G; Lenzhofer, R; Pall, H; Tomaschek, A; Ziebart-Schroth, A; Zirm, B, 1992) |
| "Amlodipine, a novel dihydropyridine calcium-antagonist, was compared to slow-release nifedipine in a short-term study on 40 patients with mild to moderate essential hypertension, in order to assess the efficacy and tolerability of two different dihydropyridine calcium-antagonists with short and long half-life." | 5.07 | [A comparison between amlodipine and nifedipine retard in patients with essential arterial hypertension]. ( Bruzzone, F; Canale, C; Caponnetto, S; Lonati, A; Malvestiti, FM; Masperone, MA; Terrachini, V, 1992) |
| "A multicenter, randomized double-blind study of 6 months' duration was performed in 540 patients (average age 54 years, 57% male) with mild-to-moderate essential hypertension to determine the relative effects on quality of life of cilazapril, atenolol, and nifedipine retard." | 5.07 | Quality of life with three antihypertensive treatments. Cilazapril, atenolol, nifedipine. ( Bulpitt, CJ; Chase, DM; Collins, WC; Fletcher, AE; Furberg, CD; Goggin, TK; Hewett, AJ; Neiss, AM, 1992) |
| "The frequency and severity of adverse effects during the first 14 days of treatment with amlodipine (5 mg once daily), nifedipine retard (20 mg twice daily) or placebo were compared in a multicentre, three-way, cross-over study involving 97 patients with mild-to-moderate hypertension." | 5.07 | Comparison of early side effects with amlodipine and nifedipine retard in hypertension. ( Bremner, AD; Fell, PJ; Hosie, J; James, IG; Saul, PA; Taylor, SH, 1992) |
| "Data from 2 separate multicenter, double-blind clinical studies following the same protocol, except for the selection of doses, were pooled to evaluate the efficacy and tolerability of fixed doses of a new sustained-release (SR) formulation of nifedipine compared with placebo in 388 patients with mild to moderate uncomplicated essential hypertension." | 5.07 | Effectiveness of once-daily monotherapy with a new nifedipine sustained release calcium antagonist. ( Bottini, PB; Carr, AA; Devane, JG; Feig, P; Fisher, L; MacCarthy, EP; Mulligan, S; Prisant, LM; Rhoades, RB, 1992) |
| "Thirty-nine black patients with mild to moderate hypertension were treated for 1 year with various long-acting preparations of nifedipine, during which time serial changes in 24-hour ambulatory blood pressure (BP), exercise performance, left ventricular (LV) mass index and LV systolic function were evaluated." | 5.07 | Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension. ( Davis, J; Essop, MR; Middlemost, SJ; Sack, M; Sareli, P; Skoularigis, J; Wisenbaugh, T, 1992) |
| "Six men with borderline hypertension took felodipine 5 mg with water, grapefruit juice, or orange juice." | 5.07 | Interaction of citrus juices with felodipine and nifedipine. ( Arnold, JM; Bailey, DG; Munoz, C; Spence, JD, 1991) |
| "The efficacy and safety of isradipine and nifedipine retard were compared in 51 patients with mild-to-moderate essential hypertension." | 5.07 | First clinical experience with isradipine in the treatment of hypertension in Portugal. ( Botelho, MA; Correia, JM; Mariano-Pego, G; Rocha-Gonçalves, F; Viegas, J, 1991) |
| "Carvedilol is a novel treatment for hypertension, having a balanced pharmacology of vasodilation and beta-receptor blockade." | 5.07 | A comparative study of carvedilol, slow-release nifedipine, and atenolol in the management of essential hypertension. ( Ball, SG; Dixon, S; Hall, S; Hallman, RJ; Harvey, RE; Prescott, RI, 1991) |
| "In 80 patients with moderate hypertension the effects of nisoldipine 10 mg b." | 5.07 | The effects of nisoldipine, diltiazem, nifedipine, and verapamil on hemodynamic parameters and red blood cells-platelet interactions in patients with arterial hypertension. ( Belousov, Y; Kushnaryov, V, 1991) |
| "The effects of the nifedipine gastrointestinal therapeutic system (GITS) on blood pressure (BP), systemic vascular resistance (SVR), and left ventricular (LV) performance were determined in eight patients with essential hypertension." | 5.07 | Nifedipine improves left ventricular function in patients with hypertension. ( Boucher, CA; Christensen, DM; Higgins, J; Zusman, RM, 1991) |
| "The aim of this study was to compare the antihypertensive efficacy and tolerability of lacidipine, a new dihydropyridine calcium antagonist, and slow-release nifedipine (SR) in patients with mild-to-moderate essential hypertension." | 5.07 | Comparative study of lacidipine and nifedipine SR in the treatment of hypertension: an Italian multicenter study. The Northern Italian Study Group of Lacidipine in Hypertension. ( Leonetti, G, 1991) |
| "Effect of sublingual nifedipine was evaluated in 39 cases of hypertensive emergencies (diastolic blood pressure greater than or equal to 120 mm Hg with impending organ failure, loss of vital function or death)." | 5.07 | Sublingual nifedipine in hypertensive emergencies with special reference to cerebrovascular accident. ( Gambhir, IS; Gupta, SS; Singh, DS, 1991) |
| "In 10 patients with moderate essential hypertension, the neurohumoral and hemodynamic effects of 4 days' treatment with 2 x 75 micrograms clonidine (C), 2 x 20 mg nifedipine retard (N), and a combination of the two (C/N) were studied and compared with baseline values." | 5.07 | [Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances]. ( Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "The effects of nisoldipine and slow release nifedipine on mild to moderate hypertension and glycaemic control were studied in 28 diabetic hypertensives, all except one of whom were non-insulin dependent." | 5.07 | Nifedipine and nisoldipine in hypertensive diabetics. ( Clarke, CW; Kubik, MM, 1991) |
| " The study was based on a randomized, crossover design to compare the effect of an NSAID, sulindac, with that of another NSAID, diclofenac sodium, in the hypertension treatment." | 5.07 | No adverse effect of non-steroidal anti-inflammatory drugs, sulindac and diclofenac sodium, on blood pressure control with a calcium antagonist, nifedipine, in elderly hypertensive patients. ( Abe, K; Sato, K; Sato, M; Takeuchi, K; Tanno, M; Yasujima, M; Yoshinaga, K, 1991) |
| "The short-term effects of atenolol and nifedipine on plasma levels of atrial natriuretic peptide (ANP), plasma renin activity (PRA), and plasma aldosterone (PA) were studied in two groups of patients with uncomplicated essential hypertension." | 5.07 | Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension. ( Bucci, V; Casale, R; Colantonio, D; Desiati, P; Giandomenico, G; Pasqualetti, P, 1991) |
| "Sixteen patients with severe hypertension were treated for 1 year with extended release nifedipine, during which time serial changes in left ventricular mass index and associated alterations in left ventricular systolic function, left ventricular filling, plasma renin activity, atrial natriuretic peptide and catecholamines were evaluated." | 5.07 | Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991) |
| "Twelve patients with essential hypertension who were already on treatment with the long-acting calcium antagonist amlodipine (5 mg once daily) were entered into a double-blind, randomized crossover study of the addition of one month's treatment with either bendrofluazide (5 mg once daily) or matching placebo." | 5.07 | A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
| "Nifedipine causes an acute and a sustained reduction in sodium balance in patients with essential hypertension." | 5.07 | Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Miller, MA; Sagnella, GA; Singer, DR, 1991) |
| "Hemodynamic Effects of Isradipine and Nifedipine in Hypertension Myocardial wall tension is an important determinant of the oxygen demand, the function and the degree of hypertrophy of the left ventricle." | 5.07 | [The hemodynamic effects of isradipine and nifedipine in hypertension]. ( Burger, KJ; Distler, GA; Gross, P; Koppenhagen, K; Welzel, D; Wudel, E, 1991) |
| "The effects of amlodipine on ambulatory blood pressure were investigated in patients with mild-to-moderate hypertension." | 5.07 | A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure. ( Burris, JF; Klein, J; Mroczek, WJ, 1991) |
| "Amlodipine (once daily) and captopril (twice daily) had comparable efficacy and safety in reducing the blood pressure of patients with mild and moderate essential hypertension." | 5.07 | A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results. ( Guevara, J; Hernández, O; Hernández, R; Urbina, A; Velasco, M, 1991) |
| "This study compared the efficacy and safety of 8 weeks of open treatment with the dihydropyridine calcium antagonists amlodipine and nitrendipine in mild-to-moderate hypertension." | 5.07 | Amlodipine compared to nitrendipine for the treatment of mild-to-moderate hypertension. ( Beressem, P; Englert, R; Kramar, M; Stafunsky, M; von Manteuffel, E, 1991) |
| "Twenty-one subjects with mild or moderate systemic hypertension were treated for 12 weeks with amlodipine, a new calcium antagonist of the dihydropyridine group." | 5.07 | Efficacy and tolerability of amlodipine in patients with mild-to-moderate hypertension. ( Meaney, E; Moguel, R; Olvera, R; Samaniego, V, 1991) |
| "The antihypertensive efficacy of amlodipine was studied in 22 patients (16 female, six male) with mild-to-moderate hypertension." | 5.07 | Clinical evaluation of amlodipine, a new long-acting calcium antagonist, in mild and moderate hypertension. ( Escudero, J; Hernandez, H, 1991) |
| "Forty-four patients with arterial hypertension of any cause were selected and randomly divided in three groups: P group, consisting of 9 patients who received placebo; N group, consisting of 17 patients, 8 males, mean age of 47 years who received 10 mg of sublingual nifedipine; C group, consisting of 18 patients, 6 males, with mean age of 47 years who received 0." | 5.07 | [Acute reduction of blood pressure: comparative study of nifedipine and clonidine]. ( Abzaid, A; de Castro, EG; Dondici Filho, J; Gomes, JC; Luz, NS, 1991) |
| "The main aim of this study was to investigate whether a new slow-release formation of nicardipine can control hypertension and whether its antihypertensive effect is manifest throughout the dose intervals." | 5.07 | Double-blind, randomized comparative study of the antihypertensive effect of nicardipine slow-release and nifedipine slow-release in hypertensive patients with coronary heart disease. ( Glocke, MH; Griebel, A; Maetzel, FK; Teufel, WE, 1991) |
| "The effect of nifedipine on serum theophylline levels in 13 female hypertensive patients having asthma on theophylline therapy has been investigated." | 5.07 | Nifedipine alters serum theophylline levels in asthmatic patients with hypertension. ( Canberk, A; Eroğlu, L; Yilmaz, E, 1991) |
| "Twenty patients with acute severe hypertension were randomised to therapy with either nifedipine capsules (10 mg) or captopril tablets (25 mg) given sublingually and the blood pressure recorded for 240 minutes." | 5.07 | Captopril, nifedipine and their combination for therapy of hypertensive urgencies. ( Jennings, AA; Opie, LH; Schneider, E, 1991) |
| "Forty-nine patients, with ages ranging from eighteen to seventy years and with mild to moderate primary hypertension (sitting diastolic blood pressure of greater than or equal to 95 mmgH and less than or equal to 115 mmHg) were randomized into a twenty-one-week, double-blind, prospective study to determine the effects of monotherapy of nifedipine GITS (gastrointestinal therapeutic system) versus atenolol on serum lipids, lipid subfractions, apolipoproteins, (apo), and blood pressure (BP)." | 5.07 | Effects of nifedipine GITS and atenolol monotherapy on serum lipids, blood pressure, heart rate, and weight in mild to moderate hypertension. ( Burger, MC; Houston, MC; Olafsson, L, 1991) |
| "To examine predictors for the efficacy of antihypertensive agents, we investigated the effects of nifedipine and captopril on blood pressure (BP) and humoral factors in patients with essential hypertension." | 5.07 | Plasma renin activity and norepinephrine as predictors for antihypertensive effects of nifedipine and captopril. ( Atarashi, K; Kajiyama, G; Kusaka, M; Matsumoto, K; Matsuura, H; Shingu, T; Sumida, Y, 1991) |
| " Thirteen male subjects with essential hypertension received a single oral 20-mg dose of nifedipine or 120 mg of diltiazem." | 5.07 | Natriuretic effect of calcium-channel blockers in hypertensives. ( Deuter, G; Kapoor, SC; Krishna, GG; Narins, RG; Riley, LJ, 1991) |
| "Randomised study of diabetic patients with microalbuminuria treated with perindopril or nifedipine for 12 months and monitored for one or three months after stopping treatment depending on whether they were hypertensive or normotensive." | 5.07 | Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group. ( , 1991) |
| "Sublingual captopril (25 mg) was compared with sublingual nifedipine (10 mg) to determine their effectiveness and safety in the treatment of hypertensive emergencies." | 5.07 | Comparison of sublingual captopril and nifedipine in immediate treatment of hypertensive emergencies. A randomized, single-blind clinical trial. ( Angeli, P; Caregaro, L; Chiesa, M; Gatta, A; Merkel, C; Rondana, M; Sacerdoti, D, 1991) |
| "The effect of Hydergine/Nifedipine (Pontuc) on blood pressure in supine or exercise blood pressure as well as subjective well-being was evaluated in a randomized, double-blind interindividual comparison with Nifedipine in 50 elderly out-patients (34 females, 16 males) with mostly pretreated isolated systolic hypertension." | 5.07 | [Therapy comparison between the combination hydergine/nifedipine and nifedipine alone in patients with isolated systolic hypertension]. ( Dominiak, P; Weidinger, G, 1991) |
| "After screening a local population in the northern part of The Netherlands for hypertension, 125 patients (116 of whom had not previously used antihypertensive drugs) with a five times elevated diastolic pressure (DP) of between 95 and 130 mmHg were randomized and treated daily either with atenolol 50 mg o." | 5.07 | Captopril compared to atenolol in mild to moderate hypertension in a randomized double-blind controlled trial. ( Havinga, TK; May, JF; Schuurman, FH; ten Berge, BS; van der Veur, E; Wesseling, H, 1991) |
| "17 patients with isolated systolic hypertension (ISH) and 8 with diastolic hypertension (DH) were treated with 10 mg of nifedipine sublingually." | 5.07 | [Clinical effects of nifedipine on blood pressure and left ventricular performance in patients with isolated hypertension]. ( Hua, Q; Tang, Z; Wang, JR, 1991) |
| "Various aspects of carbohydrate and lipid metabolism have been studied in two groups of patients with mild hypertension before and after four months of treatment with either nifedipine (n = 12) or atenolol (n = 12)." | 5.07 | Comparison of the effects of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertension. ( Chen, YD; Hoffman, B; Reaven, GM; Sheu, WH; Swislocki, AL, 1991) |
| "The incidence and prevalence of cough related to enalapril was assessed by spontaneous reporting and a visual analogue scale during a 6 month random double-blind parallel-group study comparing enalapril with nifedipine." | 5.07 | Cough and enalapril: assessment by spontaneous reporting and visual analogue scale under double-blind conditions. ( Maclean, D; Ramsay, LE; Richardson, PJ; Yeo, WW, 1991) |
| "To evaluate differences in efficacy, safety, and quality of life, 394 male patients with mild-to-moderate hypertension were randomized to receive 20 weeks of either atenolol or nifedipine gastrointestinal therapeutic system (GITS) in a multicenter double-blind trial." | 5.07 | Assessment of quality of life by patient and spouse during antihypertensive therapy with atenolol and nifedipine gastrointestinal therapeutic system. ( Anderson, RB; Hollenberg, NK; Testa, MA; Williams, GH, 1991) |
| "A study was undertaken to assess the use of intravenous nifedipine in controlling hypertension in patients following coronary artery surgery." | 5.06 | Intravenous nifedipine for control of hypertension in patients after coronary artery bypass graft surgery. ( Davis, ME; Feneck, RO; Jones, CJ; Walesby, RK, 1988) |
| "Forty outpatients (11 men and 29 women) aged between 65 and 85 years (mean age of 68 years) with mild to moderate hypertension [mean systolic/diastolic blood pressure (SBP/DBP) after 2 weeks on placebo of 175/102 mm Hg] were included in a randomized, double-blind, parallel-group study to compare the efficacy and tolerance of 10 mg of bisoprolol once daily (o." | 5.06 | Bisoprolol and nifedipine SR in the treatment of hypertension in the elderly. ( Carretero, J; Garcia, MJ; Garrido, M; Oliván Martinez, J; Pizarro, JL; Rodriguez Botaro, A, 1990) |
| "The new calcium antagonist isradipine was compared with nifedipine retard in a multicenter, double-blind, placebo-controlled, randomized study involving 159 patients with mild hypertension." | 5.06 | Calcium antagonists as first-line antihypertensive agents: a placebo-controlled, comparative trial of isradipine and nifedipine. ( Burger, KJ; Weidinger, G; Welzel, D, 1990) |
| "The long-term haemodynamic responses to amlodipine, a new long-acting calcium antagonist, were studied both at rest and during exercise in 18 patients (mean age 43 years) with essential hypertension." | 5.06 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1990) |
| "In patients with hypertension persisting on combined diuretic and beta-blocker therapy, the effects of an additional 9-week therapy with a calcium antagonist (nifedipine) versus a classical arterial vasodilator (hydralazine) were compared for changes in blood pressure (BP), plasma catecholamines (n = 15), and left ventricular (LV) systolic and diastolic function (n = 6)." | 5.06 | Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy. ( Burns, RJ; Frankel, D; Leenen, FH; Myers, MG, 1990) |
| "The effects of nifedipine on blood pressure (BP), left ventricular hypertrophy, and diastolic function were evaluated in 14 patients with essential hypertension (EH)." | 5.06 | Early regression of left ventricular diastolic abnormalities in hypertensive patients treated with nifedipine. ( Arcaro, G; Arosio, E; Covi, G; Lechi, A; Montresor, G; Sheiban, I; Tonni, S; Zenorini, C, 1990) |
| "Nifedipine, in the gastrointestinal therapeutic system (GITS) formulation, a controlled-release formulation for once-a-day administration, was evaluated in the Modern Approach to the Treatment of Hypertension (MATH) trial." | 5.06 | Nifedipine gastrointestinal therapeutic system in the treatment of hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension (MATH) Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the therapeutic safety and efficacy of the once-a-day nifedipine gastrointestinal therapeutic system (GITS) formulation in a large and diverse cohort of patients with mild-to-moderate hypertension." | 5.06 | Antihypertensive effectiveness of nifedipine gastrointestinal therapeutic system in the elderly. The Modern Approach to the Treatment of Hypertension (MATH) Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| " The Modern Approach to the Treatment of Hypertension (MATH) trial was conducted to determine the efficacy and safety of the new once-daily nifedipine gastrointestinal therapeutic system (GITS) formulation in a large cohort of mild-to-moderate hypertensive patients overall, and to identify specific effects of therapy in the presence of complicating factors such as diabetes and obesity." | 5.06 | Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group. ( Bravo, EL; Friedman, CP; Krakoff, LR; Tuck, ML, 1990) |
| "This study was performed to assess the effect of a calcium channel blocker (nifedipine) and beta-blockade (atenolol) on left ventricular early diastolic function and filling in essential hypertension (WHO stage I, II; HT)." | 5.06 | [Effects of calcium antagonists or beta-blockade on left ventricular diastolic function in essential hypertension]. ( Arita, M; Fujiwara, S; Masuyama, Y; Nakamura, N; Nakamura, Y; Nakatsu, C; Nishio, I; Ohshika, H; Shiotani, M; Ueno, Y, 1990) |
| "The effectiveness and safety of sustained action nifedipine (NF) were compared to those of chlorthalidone (CL) in two groups of 35 and 37 patients with mild to moderate hypertension followed up for 4 months." | 5.06 | [Comparison of chlorthalidone and sustained-action nifedipine in the treatment of mild to moderate arterial hypertension]. ( Calderón de la Barca Gázquez, JM; de Diego Cabrera, MS; González Santos, C; Iribarren Marín, MA; Martínez de la Iglesia, J; Pérula Torres, L, 1990) |
| "The arterial vasodilator properties of the dihydropyridine calcium antagonist amlodipine were compared with the effects of vascular muscle cyclic guanosine monophosphate production by sodium nitroprusside and with the effects of a combined infusion of amlodipine and the nondihydropyridine calcium antagonist verapamil in 8 untreated patients with primary hypertension." | 5.06 | Arterial vasodilator effects of the dihydropyridine calcium antagonist amlodipine alone and in combination with verapamil in systemic hypertension. ( Bühler, FR; Erne, P; Kiowski, W; Linder, L, 1990) |
| "The calcium antagonists of the dihydropyridine group, isradipine and nifedipine, were compared in 64 patients with mild to moderate hypertension (diastolic blood pressure 95 to 110mm Hg)." | 5.06 | The calcium antagonist isradipine in the therapy of hypertension. A double-blind crossover comparison with nifedipine. ( Burger, KJ; Welzel, D, 1990) |
| "The long acting angiotensin-converting enzyme inhibitor enalapril was compared with the calcium channel blocker nifedipine as sustained-release formulation in 136 patients with mild to moderate hypertension." | 5.06 | Comparative efficacy and safety of enalapril and sustained-release nifedipine in patients with mild to moderate hypertension. The Enalapril vs Nifedipine French Study Group. ( Artigou, JY; Benichou, M; Berland, J; Fressinaud, P; Grollier, G; Gueret, P; Nguyen, CD, 1990) |
| "In a double-blind, randomized, multicenter study of 194 patients with moderate hypertension, spironolactone and nifedipine were found to reduce blood pressure (BP) to about the same extent and in the same percentage of patients after 45 days of treatment (47 and 50%, respectively)." | 5.06 | Spironolactone versus nifedipine in essential hypertension. ( Capron, MH; Henry, M; Pelletier, B; Wehrlen, M, 1990) |
| "The aim of the study was (1) to determine the difference in aortic input impedance and derived parameters between hypertensives and normotensives; and (2) to assess the acute effects of nifedipine on the aortic impedance, compliance, and resistance in patients with hypertension." | 5.06 | Effects of nifedipine on systemic hydraulic vascular load in patients with hypertension. ( Chang, KC; Chen, HI; Hsieh, KS; Kuo, TS, 1990) |
| "The effect of anapriline, corinfar and reserpine on parameters of hemodynamics and plasma testosterone was evaluated in 60 juvenile hypertension patients who achieved pronounced hypotensive response." | 5.06 | [Effect of the treatment on hemodynamic indicators and plasma testosterone level in patients with juvenile hypertension]. ( Chernoguz, LS; Krishchuk, AA; Kupchinskaia, EG; Popova, LI; Savitskiĭ, SIu; Zanozdra, NS, 1990) |
| "This randomised, parallel group study was designed to compare the efficacy of nifedipine (40 mg once daily) combined with either the dopamine agonist, co-dergocrine mesilate (4 mg once daily) or the diuretic mefruside (25 mg once daily) in 40 patients with essential arterial hypertension and a diastolic blood pressure greater than 105 mmHg." | 5.06 | Influence of co-dergocrine mesilate/nifedipine compared to mefruside/nifedipine on circadian blood pressure in patients with essential hypertension. ( Heintz, B; Heller, A; Kirsten, R; Nelson, K, 1990) |
| "Antihypertensive effects of labetalol and nifedipine were evaluated in a double blind cross over trial in ambulatory patients with moderately severe hypertension (mean diastolic BP 101." | 5.06 | Labetalol and nifedipine in the management of essential hypertension. ( Prasad, NK, 1990) |
| "Forty-one elderly patients with mild to moderate hypertension (resting diastolic blood pressure 100-130 mmHg after an eight week placebo run-in phase) were randomised to a double-blind parallel group comparison of nifedipine retard 10 mg twice daily or atenolol 50 mg once daily." | 5.06 | Comparative trial of nifedipine retard and atenolol in the treatment of elderly patients with mild to moderate hypertension. ( Clamp, M; Holmes, B; Wilcox, R, 1990) |
| "The anti-hypertensive effects of slowly absorbable nifedipin in doses of 20-40 mg twice daily and 25-50 mg captopril twice daily were investigated in a randomized cross-over trial on 19 patients with slight to moderate hypertension." | 5.06 | [The effects of nifedipine and captopril on blood pressure, clinical chemical parameters and general health]. ( Birkebaek, NH; Vejby-Christensen, H, 1990) |
| "We assessed the efficacy of long-acting nifedipine as monotherapy in 52 patients with mild to moderate essential hypertension in a randomized, controlled crossover study." | 5.06 | Long-acting nifedipine versus metoprolol as monotherapy for essential hypertension. A randomized, controlled crossover study. ( Pun, CO; Woo, KS, 1990) |
| "Ketanserin, the specific S2 serotonin antagonist, is undergoing evaluation for the therapy of hypertension of all degrees of severity." | 5.06 | Effects of intravenous ketanserin on severely hypertensive patients with double-blind crossover assessment of central side-effects. ( Jennings, AA; Opie, LH, 1987) |
| "A total of 136 patients with mild to severe uncomplicated essential hypertension were evaluated in a multicenter, randomized, double-blind, double-placebo, parallel study to compare the effect of lisinopril, a new angiotensin-converting enzyme inhibitor, with that of nifedipine." | 5.06 | Comparative trial of lisinopril and nifedipine in mild to severe essential hypertension. ( Baglivo, H; Boeijinga, JK; Breckenridge, AM; Clement, D; Johnston, GD; Klein, W; Kramer, R; Luccioni, R; Meurer, KA; Mörlin, C, 1987) |
| " The effects of intraarterially infused nifedipine, reactive hyperemia after 10 min arterial occlusion combined with handgrip exercise and local heating, and arterial occlusion combined with nifedipine on forearm blood flow and blood pressure were investigated in random order." | 5.06 | Effects of reactive hyperemia and nifedipine on forearm vascular resistance in essential hypertension: evidence for functional abnormality. ( Braun, J; Distler, A; Gotzen, R; Meyer-Sabellek, W; Schulte, KL, 1987) |
| "The effects of two antihypertensive agents, nifedipine (N) and captopril (C), on left ventricular (LV) mass and volume were studied in 16 patients with essential hypertension (8 treated with N and 8 with C for 6 months) by means of a complete M-mode echocardiogram monitored by two-dimensional echocardiography." | 5.06 | Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril. ( Accardi, R; Arcaro, G; Covi, G; Lechi, A; Sheiban, I; Zenorini, C, 1987) |
| "The acute blood pressure response to an angiotensin converting enzyme inhibitor (enalaprilat) was compared in patients with uncomplicated essential hypertension with that obtained under similar conditions with a calcium entry blocker (nifedipine)." | 5.06 | Acute antihypertensive effect of angiotensin converting enzyme inhibition and calcium entry blockade. ( Bidiville, J; Brunner, HR; Nussberger, J; Porchet, M; Waeber, B; Waeber, G, 1987) |
| "Lisinopril, a long-acting angiotensin converting enzyme inhibitor, and the calcium channel blocker nifedipine in its retard formulation, were compared as monotherapy in a group of 45 patients with essential hypertension." | 5.06 | Comparative efficacy of lisinopril and nifedipine retard in essential hypertension: a double-blind, placebo-controlled trial. ( Breckenridge, AM; Grimmer, SF; Johnston, GD; Kondowe, G; Meany, TB; Richardson, PJ, 1987) |
| "Once-daily administration of amlodipine, a long-acting dihydropyridine calcium-channel blocker, and atenolol, a cardioselective beta-adrenoceptor blocking agent, were compared in patients with mild to moderate hypertension in a multicenter placebo-controlled trial." | 5.06 | Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension. ( Cocco, G; de Bruijn, B; Tyler, HM, 1988) |
| "Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with placebo and atenolol in 125 patients with mild to moderate systemic hypertension [supine diastolic blood pressure (DBP) 90-114 mm Hg]." | 5.06 | A randomized placebo-controlled comparison of amlodipine and atenolol in mild to moderate systemic hypertension. ( Brobyn, R; Brown, RD; Frishman, WH; Johnson, BF; Reeves, RL; Wombolt, DG, 1988) |
| "The antihypertensive efficacy of once-daily amlodipine was studied in a group of 30 patients with mild to moderate hypertension in a double-blind, placebo-controlled, parallel-group study." | 5.06 | Once-daily amlodipine in the treatment of mild to moderate hypertension. ( Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Webster, J, 1988) |
| "A multicenter, placebo-controlled trial assessed the antihypertensive efficacy and safety of different doses of amlodipine in patients with mild to moderate hypertension." | 5.06 | Amlodipine: a double-blind evaluation of the dose-response relationship in mild to moderate hypertension. ( Frick, MH; McGibney, D; Tyler, HM, 1988) |
| "Amlodipine 10 mg once daily added to captopril 25 mg twice daily for 4 weeks in patients with moderate to severe hypertension significantly improved blood pressure control (by -18/-12 and -20/-12 mm Hg for supine and standing systolic/diastolic pressures respectively, p less than 0." | 5.06 | A double-blind crossover comparison of amlodipine and placebo added to captopril in moderate to severe hypertension. ( Maclean, D; Mitchell, ET; Tyler, HM; Walker, P; Wilcox, RG, 1988) |
| "One hundred sixty patients with mild to moderate essential hypertension entered this double-blind parallel group comparison of amlodipine, verapamil, and placebo." | 5.06 | Comparison of amlodipine and verapamil in the treatment of mild to moderate hypertension. ( Lorimer, AR; Smedsrud, T; Tyler, HM; Walker, P, 1988) |
| "Amlodipine, a new long-acting dihydropyridine calcium antagonist, was compared with hydrochlorothiazie (HCTZ) in 145 patients with mild to moderate hypertension." | 5.06 | Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension. ( Ames, RP; Applegate, WB; Burris, JF; Davidov, ME; Mroczek, WJ; Ram, CV, 1988) |
| "In an acute, double-blind, crossover study on 12 patients with essential hypertension, the interaction between nifedipine and prazosin was investigated in the supine position." | 5.06 | Nifedipine-prazosin interaction in patients with essential hypertension. ( Farsang, C; Kiss, I, 1989) |
| "The antihypertensive efficacy and suitability for once daily dosing of amlodipine, a new calcium antagonist, was studied in a series of 205 patients with mild to moderate hypertension." | 5.06 | A dose-response study of amlodipine in mild to moderate hypertension. ( Frick, MH; McGibney, D; Tyler, HM, 1989) |
| "This is a double blind parallel group comparison in patients with mild-moderate hypertension, of amlodipine, verapamil and placebo." | 5.06 | A comparison of amlodipine, verapamil and placebo in the treatment of mild to moderate hypertension. Amlodipine Study Group. ( Lorimer, AR; Smedsrud, T; Tyler, HM; Walker, P, 1989) |
| "The antihypertensive effects of lisinopril 20 mg once daily and slow-release nifedipine 20 mg twice daily were compared in a double-blind, parallel group, 10-week study involving 274 patients with mild to moderate hypertension." | 5.06 | Lisinopril versus slow-release nifedipine in the treatment of mild to moderate hypertension: a multicentre study. The Cooperative Study Group. ( Serradimigni, A; Witchitz, S, 1989) |
| "The antihypertensive effectiveness and the clinical and biochemical safety of cicletanine were evaluated in 84 patients (28 women, 56 men) presenting with permanent essential hypertension without severe cardiovascular complications." | 5.06 | [Cicletanine administered with other antihypertensive agents]. ( Deschamps de Paillette, E; Grimberg, D; Tarrade, T, 1989) |
| "In a multi-center, double-blind parallel-group study involving patients with essential hypertension (grade I/II), the antihypertensive effect and toleration of the postsynaptic alpha-1 receptor blocker, urapidil, was compared with that of the calcium antagonist, nifedipine." | 5.06 | [Antihypertensive effect and tolerance to urapidil. Comparison with nifedipine in a multicenter double-blind study]. ( Feldhaus, P; Haerlin, R; Stumpe, KO, 1989) |
| " In order to examine whether nitrendipine was superior to slow release nifedipine as monotherapy in the treatment of mild to moderate essential hypertension, the two agents were administered to 22 patients in a double-blind randomized cross-over study, incorporating low and titrated dose regimes." | 5.06 | A double-blind randomized cross-over study of the efficacy and tolerability of nifedipine and nitrendipine in the treatment of mild to moderate hypertension. ( Heagerty, AM; Swales, JD, 1989) |
| "The effects of one month's treatment with each of nifedipine, verapamil, diltiazem, propranolol and placebo, given in random order, on fasting plasma glucose, haemoglobin Alc, serum fructosamine, immunoreactive insulin, cholesterol, and triglyceride were studied in a group of 19 patients with hypertension and non-insulin dependent diabetes mellitus." | 5.06 | The effects of verapamil, diltiazem, nifedipine and propranolol on metabolic control in hypertensives with non-insulin dependent diabetes mellitus. ( Chellingsworth, MC; Kendall, MJ; Pasi, J; Singh, BM; Wright, AD, 1989) |
| "The antihypertensive effects of nisoldipine, a calcium channel blocker, and atenolol, a beta-adrenergic blocker, were compared in patients with mild or moderate essential hypertension." | 5.06 | Comparison of nisoldipine and atenolol in the treatment of essential hypertension. ( Fukuyama, M; Okabayashi, H; Takahashi, H; Yoneda, S; Yoshimura, M, 1989) |
| "The relationship between the age and the clinical efficacy of a new long acting calcium entry blocker, nisoldipine, was investigated in essential hypertension using two double blind group studies, in which nifedipine or atenolol was used as a control drug." | 5.06 | [Age and efficacy of new long acting calcium blocker, nisoldipine, is essential hypertension]. ( Kaneko, Y; Kuwajima, I; Takeda, T, 1989) |
| "Recommendations for prevention of hypertension and tachycardia during the induction of anesthesia include the use of fentanyl and antihypertensive drugs and superficial anesthesia of the throat." | 5.06 | [The effect of nifedipine and fentanyl on changes in the circulatory reaction to endotracheal intubation]. ( Fauth, U; Halmágyi, M; Heinrichs, W; Karim, S; Tzanova, I, 1989) |
| "This double-blind placebo controlled study investigated the antihypertensive and humoral effects of nifedipine capsules in patients with essential hypertension inadequately controlled (seated diastolic blood pressure greater than or equal to 95 mm Hg) by hydrochlorothiazide (HCTZ) alone." | 5.06 | Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone. ( Abraham, PA; Halstenson, CE; Opsahl, JA, 1989) |
| "We studied the incidence of oedema 2 weeks following initiation of nifedipine therapy for hypertension in a group of 10 diabetic subjects, and also measured skin blood flow (SBF) with a laser Doppler flowmeter, before and after lowering the foot." | 5.06 | Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients. ( Rayman, G; Tooke, JE; Williams, SA, 1989) |
| "The effect of nifedipine (Adalat; Bayer-Miles)--a calcium channel blocker, which has a well-established place in nonobstetric hypertension--was compared with dihydralazine in 33 primigravidas with severe hypertension of pregnancy." | 5.06 | Nifedipine in acute hypertensive emergencies in pregnancy. ( Becker, P; Moodley, J; Seabe, SJ, 1989) |
| " Preliminary experience suggests that the gastrointestinal therapeutic system (GITS) push-pull osmotic pump formulation of nifedipine is safe and efficacious in the treatment of hypertension." | 5.06 | The nifedipine gastrointestinal therapeutic system in the treatment of hypertension. ( Frishman, WH; Garofalo, JL; Greenberg, SM; Rothschild, A; Rothschild, M; Soberman, J, 1989) |
| "The antihypertensive efficacy and tolerability of lisinopril, a new long acting angiotensin converting enzyme inhibitor, and nifedipine, in a retard formulation, were compared in a randomized six month double-blind study, in 45 patients with essential hypertension." | 5.06 | Lisinopril in essential hypertension: a six month comparative study with nifedipine. ( Breckenridge, AM; Grimmer, SF; Johnston, GD; Kondowe, G; Meany, B; Richardson, PJ, 1987) |
| "Sixteen patients with mild to moderate essential hypertension were randomly allocated to 6 weeks of treatment with nifedipine and captopril in a crossover trial." | 5.06 | The effect of nifedipine and captopril on platelet activation and prostanoid production in essential hypertension. ( Birkebaek, NH; Jakobsen, P; Vejby-Christensen, H; Winther, K, 1988) |
| " Ketanserin or slow-release nifedipine were added to the treatment of 24 patients with hypertension uncontrolled by a thiazide diuretic plus beta-adrenoceptor antagonist in an observer-blind, randomised parallel-group study of 6 months duration." | 5.06 | Comparison of ketanserin and slow-release nifedipine added to the treatment of hypertensive patients uncontrolled by a thiazide diuretic plus beta-adrenoceptor blocker. ( Ramsay, LE; Solomon, SA; Waller, PC, 1987) |
| "A randomised double blind parallel group study was performed to compare the efficacy and acceptability of slow release nifedipine (maximum dose 40 mg twice a day) with those of atenolol (maximum dose 100 mg once a day) as single agents for the treatment of essential hypertension." | 5.06 | Nifedipine and atenolol singly and combined for treatment of essential hypertension: comparative multicentre study in general practice in the United Kingdom. Nifedipine-Atenolol Study Review Committee. ( , 1988) |
| "The haemodynamic impact of alpha- and beta-adrenoceptor blockade (labetalol) was compared with that of slow-calcium channel blockade (nifedipine) in 32 patients with sustained elevation of systemic arterial pressure (systolic blood pressure greater than 160; diastolic blood pressure greater than 95 mmHg) following a recent myocardial infarction (6-22 h)." | 5.06 | Sympathetic (alpha-beta) or calcium channel blockade for hypertensive myocardial infarction? A haemodynamic comparison of labetalol and nifedipine. ( Hussain, M; Nelson, GI; Reynolds, GW; Richmond, A; Silke, B; Taylor, SH; Verma, SP; Wilson, JA, 1988) |
| "Fifty-one patients with urgent hypertension were treated in the emergency department with either oral nifedipine or oral clonidine in a randomized double-blind prospective study." | 5.06 | Oral nifedipine vs oral clonidine in the treatment of urgent hypertension. ( Atkin, S; Brosch, F; Jaker, M; Schmid, G; Soto, M, 1989) |
| "In an open crossover comparison of propranolol and nitrendipine, 19 patients with hypertension received 40 to 160 mg propranolol and 5 to 20 mg nitrendipine twice a day." | 5.06 | Hemodynamic and metabolic effects of the calcium channel blocking agent nitrendipine. ( Johnson, BF; Marwaha, R; Romero, L, 1986) |
| "Long-acting nifedipine and nitrendipine, a nifedipine analogue, have been proposed for single-drug therapy of hypertension." | 5.06 | Nitrendipine vs. long-acting nifedipine in mild, moderate and severe hypertension. ( De Cesare, N; Galli, C; Guazzi, MD; Salvioni, A; Tamborini, G, 1986) |
| " The antihypertensive efficacy of once-daily amlodipine was studied in a group of 30 patients with mild to moderate hypertension in a double-blind, placebo controlled parallel group study." | 5.06 | Once daily amlodipine in the treatment of mild to moderate hypertension. ( Jeffers, TA; Petrie, JC; Robb, OJ; Scott, AK; Towler, HM; Webster, J, 1987) |
| "Both nifedipine and captopril are effective in the treatment of systemic hypertension in the elderly, but their effects on cardiac function in this age group have not been evaluated." | 5.06 | Comparative effects of captopril and nifedipine on diastolic and systolic cardiac function in elderly hypertensive patients. ( Churi, A; Marmor, A; Schneeweiss, A; Traub, Y; Troshar, D, 1988) |
| "The efficacy of nitroglycerine, verapamil and nifedipine in controlling post-sternotomy hypertension was compared in four groups of 20 patients anaesthetized with fentanyl 100 micrograms kg-1 undergoing elective coronary artery surgery." | 5.06 | Comparison of nitroglycerine, verapamil and nifedipine in the management of arterial pressure during coronary artery surgery. ( Bovill, JG; Gielen, J; Hoeneveld, MH; Schuller, J; van Wezel, HB, 1986) |
| "The two dihydropyridine calcium antagonists, nicardipine and nifedipine, were compared in 12 patients with both stable angina pectoris and systemic hypertension using a double-blind, crossover protocol." | 5.06 | A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension. ( Bonandi, L; Dei Cas, L; Feroldi, P; Metra, M; Nodari, S; Nordio, G; Raddino, R; Visioli, O, 1988) |
| "The effect of nifedipine on uteroplacental blood flow was investigated in nine hypertensive women in the trimester of pregnancy and compared with the effects of a placebo in nine similar hypertensive women." | 5.06 | The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy. ( Davey, DA; Davies, N; Lindow, SW; Smith, JA, 1988) |
| "In this randomised, double-blind, crossover trial, the efficacy in hypertension of atenolol and nifedipine as single agents or in combination was compared." | 5.06 | Atenolol and sustained release nifedipine alone and in combination in hypertension. A randomised, double-blind, crossover study. ( Anderton, JL; Crowe, PF; Mittra, B; Perks, WH; Stanley, NN; Vallance, BD, 1988) |
| "This randomised, double-blind, crossover study investigated the haemodynamic effects of a beta-blocker (atenolol 50mg) and a calcium antagonist (sustained release nifedipine 20mg) given either separately or in combination in 3 groups of patients with mild to moderate essential hypertension." | 5.06 | Efficacy and tolerability of atenolol, nifedipine and their combination in the management of hypertension. ( Heath, ID; Larkin, H; Stanley, NN; Thirkettle, JL; Varma, MP, 1988) |
| "The effects of the addition of a calcium entry antagonist, nifedipine (20-mg tablet twice a day), to an angiotensin converting enzyme inhibitor, captopril (25 mg three times a day), and the addition of captopril to nifedipine were observed in two separate studies in patients with essential hypertension." | 5.06 | Captopril and nifedipine in combination for moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
| "In a cross-over study in 26 patients with mild to moderate essential hypertension The antihypertensive efficacy of captopril 25 mg b." | 5.06 | Cross-over comparison between captopril and nifedipine. ( Klein, WW; Mahr, G; Stuhlinger, W, 1986) |
| "Nifedipine has been used in hypertension, mainly as a third-line drug for rapid blood pressure reduction, for over 10 years." | 5.06 | Is nifedipine a suitable first-line treatment for essential hypertension in general practice? ( Adams-Strump, BJ; Gaw, N; Langan, JJ; Murray, TS; Sullivan, FM, 1987) |
| "Twenty-nine subjects with mild to moderate essential hypertension completed this 13 week randomized, double-blind, placebo-controlled study comparing the antihypertensive effects of nifedipine GITS (N) (30-60 mg/day), hydrochlorothiazide (H) (25-50 mg/day) and placebo (P)." | 5.06 | Nifedipine GITS and hydrochlorothiazide in essential hypertension. ( Callender, K; Halperin, AK; Hashimoto, F; Jueng, C, 1987) |
| "The efficacy and safety of nifedipine in a gastrointestinal therapeutic system (GITS) push-pull osmotic pump formulation was compared with long-acting propranolol in 49 patients with mild to moderate hypertension already receiving diuretics." | 5.06 | Multicenter comparison of the nifedipine gastrointestinal therapeutic system and long-acting propranolol in patients with mild to moderate systemic hypertension receiving diuretics. A preliminary experience. ( Frishman, WH; Garofalo, JL; Greenberg, SM; Rothschild, A; Rothschild, M; Soberman, J, 1987) |
| "The results of a multicenter trial conducted in order to determine the therapeutic efficacy of the gastrointestinal therapeutic system (GITS) formulation of nifedipine in comparison with hydrochlorothiazide and placebo in the management of mild to moderate essential hypertension are presented." | 5.06 | Antihypertensive effectiveness of the nifedipine gastrointestinal therapeutic system. ( Crook, J; Garrett, B; Gavras, H; Gavras, I; Halperin, AK; Higgins, JT; Mulinari, R; Reeves, RL; Zawada, ET, 1987) |
| "In a randomised, crossover study of patients with moderate to severe essential hypertension, the effects of the calcium entry antagonist nifedipine and the beta-receptor blocking drug acebutolol were studied on their own, and in combination." | 5.06 | Nifedipine and acebutolol in combination for the treatment of moderate to severe essential hypertension. ( MacGregor, GA; Markandu, ND; Shore, AC; Singer, DR, 1987) |
| "Thirty-nine patients with mild to moderate essential hypertension participated in a parallel, single-blind study comparing 6 weeks' treatment of nicardipine hydrochloride (90 mg/day) with nifedipine (40 mg/day)." | 5.06 | Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension. ( Armstrong, C; Blackwood, R; Garnham, J, 1987) |
| "In a series of controlled studies for periods of 4 to 6 weeks comprising 103 patients altogether, and in 1 long-term trial for 1 year, various dosages of instant and sustained-release verapamil were administered in the treatment of mild and moderate essential hypertension." | 5.06 | Instant and sustained-release verapamil in the treatment of essential hypertension. ( Hals, O; Lauve, O; Midtbø, K; Storstein, L; van der Meer, J, 1986) |
| "Three therapies were used to treat 35 patients with mild to moderate systemic hypertension: (1) the cardioselective beta-adrenoceptor blocker atenolol, (2) the calcium antagonist nifedipine and (3) combination therapy for those who failed to reach the target diastolic blood pressure (BP) of less than 90 mm Hg with monotherapy." | 5.06 | Atenolol plus nifedipine for mild to moderate systemic hypertension after fixed doses of either agent alone. ( Daniels, AR; Opie, LH, 1986) |
| "In a double-blind cross-over study, the effect on blood pressure (BP), heart rate (HR) and plasma noradrenaline concentration (pNA) of placebo or felodipine given in addition to hydrochlorothiazide was studied in 12 male patients with essential hypertension, not satisfactorily controlled with the diuretic alone." | 5.06 | Treatment of essential hypertension with felodipine in combination with a diuretic. ( Elmfeldt, D; Hedner, T; Samuelsson, O; Sjögren, E, 1986) |
| "We randomized patients with severe hypertension in the Medical Intensive Care Unit to a treatment regimen of oral nifedipine or intravenous nitroprusside." | 5.06 | A randomized comparison of nifedipine and sodium nitroprusside in severe hypertension. ( Franklin, C; Mamdani, B; Nightingale, S, 1986) |
| "Twelve patients with essential hypertension on no other drug treatment were entered into a randomised crossover study of 5, 10 and 20 mg capsules of nifedipine given 3 times a day and 20 mg tablets given twice a day." | 5.06 | Dose response and length of action of nifedipine capsules and tablets in patients with essential hypertension: a randomised crossover study. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Tucker, FA, 1986) |
| "The effectiveness of nifedipine as first-line monotherapy for mild diastolic hypertension (range: 95 to 105 mm Hg) was tested in this placebo-controlled, double-blind, randomized trial." | 5.06 | Monotherapy of mild hypertension with nifedipine. ( Corkadel, LK; Fan, F; Horwitz, LD; Pacheco, JP; Reeves, RL; Wright, RA, 1986) |
| "The acute effects of buccal nifedipine 20 mg on blood pressure, renal haemodynamics and electrolyte excretion were compared in 16 untreated patients (HT) with uncomplicated arterial hypertension (WHO I-II), 11 normotensives (NT) and 6 normotensives given a placebo." | 5.06 | Acute natriuretic effect of nifedipine in hypertensive patients and normotensive controls--a proximal tubular effect? ( Christensen, CK; Krusell, LR; Lederballe Pedersen, O, 1987) |
| "A study was carried out in 16 patients with moderately severe hypertension to investigate the effects of nifedipine, given alone or combined with a diuretic, on blood pressure and on renal and platelet function." | 5.06 | Effect of nifedipine and mefruside on renal function and platelet function in hypertensive patients. ( Anderton, JL; Burnet, ME; Fiskerstrand, CE; Notghi, A, 1987) |
| "The haemodynamic effects of piretanide, acebutolol and nifedipine were tested and compared at rest and on exercise in an open study of patients with essential hypertension, grade II (WHO)." | 5.06 | [Modification of resting and effort hemodynamics in essential arterial hypertension using antihypertensive agents]. ( Wiechmann, HW, 1987) |
| "In 93 patients with hypertension uncontrolled by bendrofluazide 5 mg plus atenolol 100 mg daily, the effects of adding nifedipine (up to 60 mg/day, n = 31), prazosin (up to 20 mg/day, n = 31), or hydralazine (up to 200 mg/day, n = 31) were compared in a 6 month open random parallel group study." | 5.06 | Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker. ( Parnell, L; Ramsay, LE; Waller, PC, 1987) |
| "The antihypertensive effect of diltiazem (180-270 mg/day) and nifedipine (40-60 mg/day) in slow-release forms was assessed over 8 weeks in a double-blind parallel study in 40 subjects with essential hypertension at rest and during exercise." | 5.06 | Antihypertensive and metabolic effects of diltiazem and nifedipine. ( Distler, A; Gotzen, R; Haertenberger, A; Meyer-Sabellek, WA; Roecker, L; Schulte, KL; Thiede, HM, 1986) |
| "We studied the renal effects of nicardipine, a calcium entry blocker, in seven patients with mild-to-moderate essential hypertension." | 5.06 | Renal effects of nicardipine in patients with mild-to-moderate essential hypertension. ( Baba, T; Boku, A; Ishizaki, T; Sone, K; Takebe, K, 1986) |
| " The incidence of severe hypertension was significantly lower when nifedipine (odds ratio, 0." | 5.05 | Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis. ( Bellos, I; Daskalakis, G; Loutradis, D; Papapanagiotou, A; Pergialiotis, V, 2020) |
| "Fifty-one patients with essential hypertension, 22 males and 29 females with a mean age of 51 (range, 28 to 65 years), were studied for more than 12 months in a controlled clinical trial with nitrendipine, a new calcium antagonist agent." | 5.05 | Clinical experience with long-term nitrendipine treatment in essential hypertension. ( Lasaridis, A; Settas, L; Tourkantonis, A, 1984) |
| "Patients with mild to moderate essential hypertension were treated in four centers with hydrochlorothiazide (HCTZ) 25 mg daily for 4 weeks." | 5.05 | Comparison of nitrendipine combined with low-dose hydrochlorothiazide to hydrochlorothiazide alone in mild to moderate essential hypertension. ( Glasser, SP; Leibowitz, DA; McMahon, SG; Ram, CV; Schoenberger, JA; Vanov, SK, 1984) |
| "One-hundred and five patients with hypertension received nitrendipine (10-40 mg/day) or hydralazine (50-200 mg/day) in a double-blind randomized design." | 5.05 | Efficacy and safety comparison of nitrendipine and hydralazine as antihypertensive monotherapy. ( Deedwania, PC; Fagan, TC; Mehta, JL; Sternleib, C; Vlachakis, N, 1984) |
| "Monotherapy with the calcium antagonists verapamil, nifedipine, nitrendipine or diltiazem was shown to have a good efficacy/tolerability ratio in the treatment of patients with essential hypertension and overall blood pressure responses were comparable as well as similar to those observed with betablockers and diuretics." | 5.05 | Calcium antagonists, firstline partners for betablockers in hypertension. ( Bühler, FR, 1984) |
| "The aim of this study was to investigate and compare the effects of two calcium antagonist drugs, verapamil (VER) and nifedipine (NIF), on blood pressure (BP), heart rate (HR), plasma catecholamines (pCA), renin (PRA), plasma aldosterone (pALD), and plasma volume (PV) in a group of patients with mild to moderate essential hypertension." | 5.05 | Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension. ( Agabiti-Rosei, E; Alicandri, CL; Beschi, M; Castellano, M; Corea, L; Fariello, R; Muiesan, G; Romanelli, G, 1982) |
| "In a double-blind, cross-over study for 6 weeks that included 28 patients with essential hypertension, WHO stage I-II, the hypotensive action of verapamil (160 mg thrice daily) was compared with nifedipine (20 mg slow release twice daily)." | 5.05 | Verapamil compared with nifedipine in the treatment of essential hypertension. ( Hals, O; Midtbø, K; van der Meer, J, 1982) |
| "The antihypertensive effect of 20 mg of nitrendipine (BAY e 5009) was compared with that of 40 mg, administered orally once daily to 12 patients with essential hypertension (WHO I-II)." | 5.05 | Experience with nitrendipine--a new calcium antagonist--in hypertension. ( Andrén, L; Hansson, L; Orö, L; Ryman, T, 1982) |
| "Nifedipine (10 mg qid) and captopril (25 mg qid) were tested alone and in combination in 14 patients suffering from severe primary hypertension." | 5.05 | Calcium-channel blockade with nifedipine and angiotensin converting-enzyme inhibition with captopril in the therapy of patients with severe primary hypertension. ( Bartorelli, A; De Cesare, N; Galli, C; Guazzi, MD; Salvioni, A; Tamborini, G; Tramontana, C, 1984) |
| "In a multi-center study, nifedipine (Bay a 1040, Adalat) (10 mg capsule) was administered, in liquid form and via sublingual route, to 22 cases who were diagnosed to have clinically severe systolic hypertension, and the depressor effect of the treatment was studied over a period of 4 h." | 5.05 | Acute antihypertensive effect of nifedipine by sublingual route in cases with clinically severe systolic hypertension. A study up to 4 h after administration. ( Arakawa, M; Fueki, T; Fukuda, T; Hirakawa, S; Ito, H; Kondo, Y; Mori, N; Shibasaki, T; Watanabe, I; Yasue, T, 1984) |
| "The antihypertensive efficacy and the acceptability of nifedipine (NI, Adalat) and the usefulness of its combination with a beta 1-selective blocking drug, acebutolol (AC), were studied in a placebo controlled trial on 15 patients with moderate hypertension." | 5.05 | Acebutolol and nifedipine in the treatment of arterial hypertension: efficacy and acceptability. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Liguori, V; Petitto, M; Santomauro, M; Villari, B, 1984) |
| " We studied the effects of two calcium antagonists, nifedipine and verapamil, on blood pressure, reactivity to exogenous noradrenaline and plasma noradrenaline concentration in 10 patients with essential hypertension." | 5.05 | Hypotensive action of calcium antagonists as related to plasma noradrenaline and reactivity to noradrenaline. ( Distler, A; Philipp, T; Reeck, S; Schwietzer, G; Thiede, HM, 1983) |
| "The efficacy of nifedipine in the treatment of hypertension was assessed in 15 patients whose hypertension continued while being treated with atenolol 100 mg and bendrofluazide 5 mg daily." | 5.05 | Role of nifedipine in treatment of hypertension. ( Dollery, CT; Murphy, MB; Scriven, AJ, 1983) |
| "The antihypertensive activity of nifedipine in medium-term treatment has been studied in 30 patients affected by II and III WHO grade essential hypertension." | 5.05 | A study of the antihypertensive effect and some pharmacodynamic aspects of nifedipine in medium-term treatment. ( Castellani, S; Galanti, G; Masotti, G; Morettini, A; Poggesi, L; Scarti, L, 1984) |
| "We compared the efficacy and safety of nitrendipine with that of hydralazine in 21 subjects with essential hypertension." | 5.05 | Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension. ( Aguila, E; Baz, R; Lopez, LM; Mehta, JL, 1984) |
| " A survey of 122 patients with resistant hypertension treated long-term with nifedipine and a control group of 102 similar patients treated with hydralazine revealed that nifedipine at an average dose of 40 mg daily caused a fall in blood pressure similar to that achieved with hydralazine in a dose of 86 mg daily." | 5.05 | Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients. ( Bulpitt, CJ; Dollery, CT; Murphy, MB, 1984) |
| "Exchangeable sodium, blood volume, plasma norepinephrine, epinephrine, renin levels, and pressor responses to infused norepinephrine or angiotensin II were assessed in 10 patients with essential hypertension on placebo, following six to eight weeks of monotherapy with nifedipine, 3 X 10-20 mg/day, and after six to eight weeks on nifedipine combined with the diuretic chlorthalidone, 25 to 50 mg/day." | 5.05 | Pressor factors and cardiovascular pressor responsiveness after short-term antihypertensive therapy with the calcium antagonist nifedipine alone or combined with a diuretic. ( Beretta-Piccoli, C; Bianchetti, MG; Bomio, F; Luisoli, S; Marone, C; Weidmann, P, 1984) |
| "1 The effect of oral nifedipine has been examined in patients with hypertension in whom arterial pressure was not adequately controlled by the combination of a beta-adrenoceptor antagonist (or alpha-methyldopa) and a diuretic." | 5.05 | Nifedipine in the treatment of hypertension: report of a double-blind controlled trial. ( Bayley, S; Dobbs, RJ; Robinson, BF, 1982) |
| "The acute effects of oral administration of niludipine (Bay a 7168), a new dihydropyridine derivative Ca2+-antagonist, on blood pressure (BP), hemodynamics and plasma renin activity (PRA) were investigated in patients with essential hypertension (n = 28) and normotensive volunteers (n = 7)." | 5.05 | Acute hypotensive, hemodynamic effects of long-term treatment with niludipine, a Ca2+-antagonist, in patients with essential hypertension. Niludipine monotherapy and combination with a beta-blocker and a diuretic). ( Aoki, K; Sato, K, 1982) |
| "The magnitude and duration of the antihypertensive effect of nifedipine were studied in 7 cases of moderate essential hypertension." | 5.05 | Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension. ( Bonnet, F; Corvol, P; Thibonnier, M, 1980) |
| "In a single-dose crossover study Captopril (SQ 14225), 1 mg/kg body weight, and Nifedipine (Bay a 1040) 20 mg were administered orally to 12 hospitalized patients with essential hypertension (Stage 1 or 2, W." | 5.05 | Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension. ( Corvol, P; Menard, J; Milliez, P; Sire, O; Soto, ME; Thibonnier, M, 1981) |
| "In a double-blind trial 26 patients with essential hypertension were treated with nifedipine or placebo for 8 weeks, following a 4-week run-in-placebo period in all patients." | 5.05 | Effects of treatment with nifedipine and metoprolol in essential hypertension. ( Eggertsen, R; Hansson, L, 1982) |
| "Niludipine (Bay a 7168), a newly developed Ca2+-antagonist, was administered to eight aged patients with moderate to severe hypertension in order to study the antihypertensive effects and duration of action of a single dose as well as to evaluate the long-term effects." | 5.05 | A study on the effects of niludipine in hypertensive patients. ( Kuwajima, I; Murakami, M; Ueda, K, 1982) |
| "Because captopril alone does not control blood pressure in all patients with essential hypertension, studies were performed to assess the effect of sodium intake and of captopril combined with hydrochlorothiazide, propranolol, and nifedipine." | 5.05 | Captopril: contrasting effects of adding hydrochlorothiazide, propranolol, or nifedipine. ( MacGregor, GA; Markandu, ND; Sagnella, GA; Smith, SJ, 1985) |
| "The antihypertensive efficacy of combination therapy with the angiotensin-converting enzyme inhibitor captopril and a diuretic or a calcium antagonist was compared in 16 patients with essential hypertension with a blood pressure of over 160/95 mm Hg having triple drug therapy." | 5.05 | Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics. ( Bolli, P; Brouwer, RM; Bühler, FR; Conen, D; Erné, P; Kiowski, W, 1985) |
| "A randomized cross-over trial was undertaken on 21 occupationally active persons who had a stable mild or moderate hypertension with the purpose of comparing the effect of a beta-adreno-receptor blocking agent (atenolol) with that of a calcium channel inhibitor (nifedipine)." | 5.05 | Working ability and exercise tolerance during treatment of a mild hypertension. I. Comparison between a beta-adreno-receptor blocking drug and a calcium antagonist. ( Green, KA; Lange Andersen, K; Ottmann, W; Piatkowski, W, 1985) |
| "The antihypertensive and cardiovascular effects of nitrendipine, a calcium entry blocker similar to nifedipine, have been evaluated in a double-blind, placebo-controlled study in 20 patients with hypertension." | 5.05 | Antihypertensive and cardiovascular effects of nitrendipine: a controlled study vs. placebo. ( de Simone, G; Fasano, ML; Ferrara, LA; Gagliardi, R; Soro, S, 1985) |
| "Thirty patients with moderate to severe hypertension (diastolic blood pressure greater than or equal to 115 mmHg), after a run-in wash out period of 15 days, were treated with muzolimine at a dosage of 20 mg once daily, given at 1 p." | 5.05 | Muzolimine and nitrendipine in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Iacono, C; Petitto, M, 1985) |
| "The effectiveness and tolerability of nitrendipine (Bay e 5009) and atenolol in the treatment of mild or moderate arterial hypertension in monotherapy and in association were evaluated in a randomized double-blind study." | 5.05 | Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension. ( de Divitiis, O; Di Somma, S; Fazio, S; Galderisi, M; Petitto, M; Santomauro, M; Villari, B, 1985) |
| "The aim of this study was to compare the new vasodilator felodipine with nifedipine in 18 patients with poorly controlled hypertension." | 5.05 | Comparative trial of felodipine and nifedipine in refractory hypertension. ( Aberg, H; Lindsjö, M; Mörlin, B, 1985) |
| "116 patients from 4 clinics participated in a double blind study to assess the efficacy of (BAY l 5240), a nifedipine-acebutolol fixed combination (10 mg + 100 mg), as compared to nifedipine 20 mg in essential hypertension." | 5.05 | Effects of BAY l 5240, a fixed combination of low dose nifedipine and acebutolol on hypertension: comparison with standard dose nifedipine. ( Gfrerer, G; Gunselmann, W; Hennies, L; Hess, K; Lejeune, P; Rittgerodt, K; Schreiber, U; Winn, K, 1985) |
| "Fifty patients with mild essential (primary) hypertension entered a double-blind, parallel-group study with either nicardipine 30 mg three times daily or placebo, randomly assigned as monotherapy for 6 weeks." | 5.05 | Nicardipine hydrochloride in essential hypertension--a controlled study. ( Asplund, J, 1985) |
| "The dose-response effects of oral nicardipine on the systemic blood pressure were examined in 54 patients with uncomplicated essential hypertension (DBP greater than or equal to 100 mm Hg)." | 5.05 | Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension. ( Frais, MA; Jackson, N; Lee, P; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "In a randomised, double-blind, cross over trial, 25 patients with mild to moderate primary hypertension were given nifedipine 20-40 mg twice daily and labetalol 200-400 mg twice daily after a 4 week period on placebo, followed by the two drugs in combination." | 5.05 | Antihypertensive and metabolic effects of nifedipine and labetalol alone and in combination in primary hypertension. ( Karlberg, BE; Ohman, KP; von Schenck, H; Weiner, L, 1985) |
| "114 patients from four clinics participated in a double blind study designed to assess the efficacy of a nifedipine-acebutolol fixed combination -10 mg + 100 mg - as compared with acebutolol -200 mg- in essential hypertension." | 5.05 | Effects of a fixed combination of low dose nifedipine and acebutolol on essential hypertension: comparison with standard dose acebutolol. ( Gfrerer, G; Gunselmann, W; Hoppe, I; Lejeune, P; Mummel, P; Petersen, B; Schreiber, U; Winkler, E, 1985) |
| "In a randomized, double-blind, placebo-controlled crossover trial, diltiazem and nifedipine were compared in 10 patients with stable angina pectoris and mild to moderate hypertension (supine diastolic blood pressure greater than or equal to 90 mm Hg)." | 5.05 | Comparison of diltiazem and nifedipine for both angina pectoris and systemic hypertension. ( Allen, L; Charlap, S; Dorsa, F; Frishman, WH; Goldberger, J; Kimmel, B; Stroh, J; Strom, J, 1985) |
| "A controlled multicentre trial was organised to compare the effects of 20 mg Nifedipine tablets (N) and 2,5 mg Indapamide tablets (I) during a 4 months' treatment period after a placebo period, in 59 patients with moderate essential hypertension (n = 59)." | 5.05 | [Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension]. ( Aubert, P; Chaignon, M; Guédon, J; Lucsko, M; Rapoud, JP, 1985) |
| "The aim of this study was to test the efficacy of a 20 mg tablet preparation of nifedipine alone in twice daily dosage, in the treatment of moderate hypertension (95 greater than or equal to DBP less than or equal to 115 mmHg)." | 5.05 | [Antihypertensive effect of a new form of nifedipine compared to a beta-blocker during chronic administration]. ( Bénichou, M; Griener, L; Kerihuel, JC; Perchicot, E; Serradimigni, A, 1985) |
| "Ambulatory monitoring of BP was performed in 11 patients whose 6 suffering from systo-diastolic (group 1) and 5 from systolic hypertension only (group 2) by Pressurometer III Del Mar Avionics after placebo (P), slow release Nifedipine (srN) 20 mg b." | 5.05 | Ambulatory BP monitoring after acute administration of slow release nifedipine, alone or in combination with acebutolol, in systo-diastolic and in systolic hypertension. ( Giannola, A; Immordino, R; Indovina, G; Novo, S; Raineri, A; Strano, A, 1985) |
| "The effects of slow-release nifedipine on blood pressure and cardiac workload have been studied during bicycle exercise testing in a randomized, double blind trial in 20 patients with mild to moderate hypertension." | 5.05 | Slow-release nifedipine versus placebo in the treatment of arterial hypertension. A double blind ergometric evaluation of cardiac workload. ( de Simone, G; di Lorenzo, L; Fasano, ML; Ferrara, LA; Lauria, R, 1985) |
| "The efficacy and safety of a new slow-release formulation of nifedipine ("Adalat Retard") were assessed in a double-blind cross-over trial in 19 subjects with essential hypertension (14 male, 5 female--ages: 34-72 years), 14 of whom continued previous antihypertensive medication." | 5.05 | Slow-release nifedipine as a single or additional agent in the treatment of essential hypertension--a placebo-controlled crossover study. ( Bune, AJ; Chalmers, JP; West, MJ; Wing, LM, 1985) |
| "During a double-blind cross-over study of 3 weeks duration 42 hypertensive outpatients with prevailingly mild angina pectoris received 30 mg daily of 4-(2'-nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarbonic acid dimethylester (nifedipine, Bay a 1040, Adalat) daily or placebo, respectively." | 5.04 | [On the clinical evaluation of therapy with nifedipine in association with various anithypertensive drugs (author's transl)]. ( Kaufmann, W; Laaser, U; Meurer, KA, 1977) |
| " Oral nifedipine is now considered an alternative first-line therapy, along with intravenous hydralazine and labetalol for women presenting with pre-eclampsia." | 4.98 | Focused Update on Pharmacologic Management of Hypertensive Emergencies. ( Broscious, R; Devabhakthuni, S; Noel, ZR; Watson, K, 2018) |
| "The present evidence suggests similar efficacy between nifedipine, hydralazine and labetalol in the treatment of severe hypertension in pregnancy." | 4.98 | Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. ( Sequeira, RP; Sridharan, K, 2018) |
| " We, along with others, have recently found that nifedipine, one of the most widely used DHPs, inhibits apoptotic cell death of endothelial cells (ECs) as well as vascular inflammation and subsequently improves endothelial function in patients with cardiovascular risk factors, including hypertension and/or diabetes, thus slowing the development and progression of atherosclerosis in these patients." | 4.84 | Role of oxidative stress in the development of vascular injury and its therapeutic intervention by nifedipine. ( Matsui, T; Nakamura, K; Yamagishi, S, 2008) |
| " Extended-release nifedipine and amlodipine are the two most commonly used oral CCAs in the management of pediatric hypertension." | 4.83 | A review of calcium channel antagonists in the treatment of pediatric hypertension. ( Sahney, S, 2006) |
| "Short-acting nifedipine has been abandoned as a treatment for severe hypertension in adults as a result of significant adverse effects." | 4.82 | Safety of short-acting nifedipine in children with severe hypertension. ( Flynn, JT, 2003) |
| "Calcium channel blockers (CCBs), which include both dihydropyridines such as nifedipine and amlodipine and non-dihydropyridines (verapamil and diltiazem), are among the most widely prescribed agents for the management of essential hypertension." | 4.82 | The role of existing and newer calcium channel blockers in the treatment of hypertension. ( Basile, J, 2004) |
| "The data from The International Nifedipine Intervention as a Goal in Hypertension Treatment (INSIGHT) Study indicate that effectively reducing blood pressure can decrease the incidence of cardiovascular events in high risk patients with concomitant pathology, including diabetes and hypercholesterolemia, as well as in smokers and those with poor family history." | 4.81 | Role of calcium channel blockers in the future, in view of the INSIGHT Study. ( Rosenthal, T, 2002) |
| "Referring to the INSIGHT trial published in The Lancet, Bayer Netherlands states in an advertisement in Dutch medical journals that nifedipine reduces cardiovascular events by 50% in patients with hypertension and at least one additional risk factor." | 4.81 | [Misleading advertisement of Adalat Oros]. ( Verheugt, FW, 2001) |
| " The International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT) is the first, large, randomized, double-blind study undertaken exclusively in high-risk hypertensive patients, with CV events as a prospectively defined primary end-point." | 4.81 | Long-term protection in at-risk hypertensive patients--a role for nifedipine GITS? ( Ruilope, LM, 2002) |
| " hypertension clinical trial databases for amlodipine (Norvasc) and nifedipine in the gastrointestinal therapeutic system (GITS) formulation (Procardia XL)." | 4.80 | Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients. ( Kloner, RA; Levenstein, M; Materson, BJ; Vetrovec, GW, 1998) |
| "Nifedipine administration for hypertensive emergencies can induce neurological and cardiac events due to abrupt hypotension." | 4.80 | Hypotension and coronary events on nifedipine: reassessing nifedipine safety. ( , 1998) |
| "Nifedipine, as most calcium-antagonist drugs, is widely used for the treatment of angina pectoris and primary hypertension." | 4.80 | [Edema and skin ulcers of the lower limbs as a collateral effect of nifedipine. A clinical case report]. ( Luca, S; Romeo, S, 1999) |
| "Tradiational drug therapy choices for hypertension in pregnancy continue to be hydralazine for acute reduction of blood pressure and methyldopa for the management of chronic hypertension." | 4.79 | Use of nifedipine in the hypertensive diseases of pregnancy. ( Doering, PL; Hatton, RC; Levin, AC, 1994) |
| "The dihydropyridine group of calcium channel blockers (type II calcium blockers) and, specifically, nifedipine are safe for use in pregnancy." | 4.79 | Nifedipine and its indications in obstetrics and gynecology. ( Childress, CH; Katz, VL, 1994) |
| "META-ANALYSIS: A meta-analysis of published randomized control trials of nifedipine in hypertension and stable angina pectoris was performed." | 4.79 | Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension. ( Caubet, JF; Chalmers, TC; Cory, D; Kupelnick, B; Ross, SD; Schmid, CH; Stason, W; Whiting, G, 1996) |
| " Two main classes of CCBs, dihydropyridines and benzothiazepines, are now clinically available for the treatment of hypertension in Japan." | 4.79 | [Calcium channel blocker for therapy of patients with hypertension]. ( Nakagawa, M; Sasaki, S, 1997) |
| "In view of the important impact of small-artery structural and functional abnormalities on complications of hypertension and recent data suggesting that some antihypertensive agents may correct some of these abnormalities, a study of resistance artery structure and function in 20 well-controlled essential hypertensive patients who had received for a prolonged period of time monotherapy with the once-a-day extended release formulation of the calcium channel antagonist nifedipine (nidefipine GITS) or with the beta-blocker atenolol is reviewed." | 4.79 | Structure and function of small arteries of essential hypertensive patients following chronic treatment with once-a-day nifedipine. ( Schiffrin, EL, 1997) |
| "Nifedipine and atenolol are first choice drugs in the treatment of arterial hypertension and angina pectoris." | 4.78 | [Pharmacology and clinical use of a fixed combination of nifedipine and slow release atenolol (Niften) in the treatment of arterial hypertension and angina pectoris]. ( Verdecchia, P, 1993) |
| "Nifedipine antagonises influx of calcium through cell membrane slow channels, and sustained release formulations of the calcium channel blocker have been shown to be effective in the treatment of mild to moderate hypertension and both stable and variant angina pectoris." | 4.78 | Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders. ( Brogden, RN; Murdoch, D, 1991) |
| "The calcium channel blocker nifedipine is an effective antihypertensive agent for the treatment of severe hypertension and hypertensive crises." | 4.77 | Treatment of severe hypertension and hypertensive crises with nifedipine. ( Houston, MC, 1987) |
| " As the first dihydropyridine available for use in the United States, nifedipine controls angina and hypertension with minimal depression of cardiac function." | 4.77 | Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications. ( Katz, AM; Leach, NM, 1987) |
| "The calcium channel blocker, nifedipine, is an effective antihypertensive agent for the treatment of hypertensive urgencies and emergencies." | 4.77 | Treatment of hypertensive urgencies and emergencies with nifedipine. ( Houston, MC, 1986) |
| "This review focuses on the potential use of the calcium antagonists diltiazem, nifedipine, and verapamil in the treatment of hypertensive emergencies." | 4.77 | The role of calcium entry blockers in hypertensive emergencies. ( Bauer, JH; Reams, GP, 1987) |
| " Verapamil is extremely effective in patients with supraventricular tachyarrhythmias, hypertrophic cardiomyopathy, and the various anginal syndromes, but it appears to be ineffective or possibly even deleterious in those with pulmonary hypertension, congestive heart failure of any cause, and Raynaud's phenomenon or disease." | 4.77 | Calcium antagonists in patients with cardiovascular disease. Current perspectives. ( Hillis, LD; Winniford, MD, 1985) |
| " Nifedipine and diltiazem are effective in the relief of angina, and verapamil is used in the treatment of supraventricular tachyarrhythmias." | 4.77 | Calcium channel blocking agents: physiologic basis of nursing intervention. ( Touloukian, JE, 1985) |
| " In chronic arterial hypertension, verapamil, and especially diltiazem seem to be superior to nifedipine." | 4.76 | Treatment of hypertension with calcium channel blockers: European data. ( Klein, WW, 1984) |
| "To compare the risk of readmission in those receiving no treatment, labetalol, nifedipine or both at hospital discharge following delivery complicated by presence of hypertension." | 4.31 | Postpartum medical management of hypertension and risk of readmission for hypertensive complications. ( Connealy, B; D Dahlke, J; Lovgren, T; Yao, R, 2023) |
| "Nifedipine is one of the common calcium channel blockers (CCBs) for hypertension that induce peroxisome-proliferator-activated receptor γ coactivator 1-α, which is envisioned as a potential therapeutic target in bone disease." | 4.31 | Association between clinical use of nifedipine and the risk of osteoporosis: a nationwide retrospective cohort study. ( Chang, CM; Chen, YC; Chou, YC; Lin, MH; Lin, TK; Sun, CA; Wu, WT, 2023) |
| "This study aimed to evaluate the efficacy of nifedipine controlled-release tablets combined with sacubitril valsartan in diabetic nephropathy (DN) patients with hypertension." | 4.31 | Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension. ( Hu, L; Liu, G; Wei, Y, 2023) |
| "This retrospective multi-institutional database analysis aimed to evaluate the blood-pressure-lowering efficacy and clinical outcomes of a generic versus brand-name nifedipine for hypertension management." | 4.12 | Comparative effectiveness of generic nifedipine versus Adalat long-acting nifedipine for hypertension treatment: A multi-institutional cohort study. ( Chen, WJ; Chu, PH; Chu, YC; Ho, CT; Hsiao, FC; Lin, CP; Tung, YC; Tzyy-Jer, H, 2022) |
| "A retrospective cohort study of patients with severe peripartum hypertension (systolic blood pressure ≥ 160 mmHg and/or diastolic blood pressure ≥ 110 mm Hg confirmed within 15 min) to determine whether the effectiveness of blood pressure control using nationally recommended medications (hydralazine, labetalol, nifedipine) differed by race/ethnicity." | 4.12 | Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension. ( Greene, NH; Kilpatrick, SJ; Pon, FF, 2022) |
| "To assess whether readmission for hypertension by 6 weeks postpartum differed between patients discharged on nifedipine or labetalol." | 4.12 | Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine. ( Do, SC; Druzin, ML; El-Sayed, YY; Girsen, AI; Herrero, T; Kan, P; Leonard, SA; Lyell, DJ; Panelli, DM, 2022) |
| "In patients with hypertension and dementia, nifedipine was associated with increased mortality risk (aHR 1." | 4.02 | Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study. ( Eriksdotter, M; Garcia-Ptacek, S; Kalar, I; Kramberger, MG; Schwertner, E; Secnik, J; von Euler, M; Winblad, B; Xu, H, 2021) |
| "In a prospective, multicenter, observational study, Chinese patients with CKD and uncontrolled hypertension were given nifedipine GITS 60 mg with a primary endpoint of change in office systolic BP (SBP) at 12 weeks." | 4.02 | Effectiveness and Tolerability of Nifedipine GITS in Patients with Chronic Kidney Disease and Uncontrolled Hypertension: A Prospective, Multicenter, Observational Study (ADRENAL). ( Chen, J; Chen, Q; Cheng, H; Hong, F; Huang, J; Li, R; Li, W; Liu, C; Liu, J; Lv, R; Shen, S; Song, W; Wang, H; Wang, J; Wei, L; Wu, H; Xiao, H; Yu, F; Zhang, T; Zhang, X, 2021) |
| " The American College of Obstetricians and Gynecologists recommends that acute-onset, severe hypertension be treated with first line-therapy (intravenous labetalol, intravenous hydralazine or oral nifedipine) within 60 minutes to reduce risk of maternal morbidity and death." | 3.96 | Identification of factors associated with delayed treatment of obstetric hypertensive emergencies. ( Akerman, MB; Elsayad, A; Halpern, TA; Heiselman, CJ; Heo, HJ; Kantorowska, A; Muscat, JC; Sicuranza, GB; Vintzileos, AM, 2020) |
| "So the objective of the present work was to formulate an advanced drug delivery system in the form of bio-responsive microneedles by incorporating nifedipine, a cardiodepressant and diltiazem, a vasodilator for effective synergism in the treatment of hypertension." | 3.96 | Engineering of Nanospheres Dispersed Microneedle System for Antihypertensive Action. ( Sardesai, M; Shende, P, 2020) |
| "The animals were treated for 56 days, 28 days with N (ω) -nitro-L-arginine methyl ester to induce hypertension, and then treated for another 28 days with the new di- hydropyridine and the standard drug nifedipine." | 3.96 | Long-chain fatty dihydropyridines: Docking calcium channel studies and antihypertensive activity. ( Cabrera, DDC; D'Oca, MGM; de Oliveira, MWB; Gonçalves, CAN; Machado, KDS; Nery, LEM; Santa-Helena, E; Scaini, JLR; Werhli, AV, 2020) |
| " This nationwide retrospective database analysis aimed to evaluate the efficacy and safety of a generic versus brand-name nifedipine for hypertension treatment." | 3.96 | Efficacy and safety outcomes of one generic nifedipine versus ADALAT long-acting nifedipine for hypertension management. ( Chen, WJ; Chu, PH; Chu, YC; Hsiao, FC; Hsu, TJ; Lin, CP; Tung, YC, 2020) |
| "Nifedipine, a known substrate to breast cancer resistance protein (ABCG2/BCRP), is used for the treatment of hypertension during breastfeeding." | 3.91 | ABCG2 c.421C>A polymorphism alters nifedipine transport to breast milk in hypertensive breastfeeding women. ( Benzi, JRL; de Carvalho Cavalli, R; de Moraes, NV; de Oliveira Filgueira, GC; Duarte, G; Malfará, BN; Zanelli, CF, 2019) |
| "The aim of the current study was to assess the association between 3 different calcium channel blockers (CCBs) (nifedipine, amlodipine and felodipine) and gingival overgrowth in patients with a diagnosis of severe refractory hypertension." | 3.88 | Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients. ( de Souza, RC; Ferreira, DC; Fischer, RG; Gonçalves, LS; Vidal, F, 2018) |
| " Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury." | 3.85 | Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017) |
| "In 1710 mild to moderate hypertension patients switching treatment from amlodipine or lercanidipine to barnidipine monotherapy or in combination with other antihypertensive drug classes, mean blood pressure decreased during 3-month follow-up." | 3.85 | Replacement of Amlodipine and Lercanidipine by Barnidipine: Tolerability and Effectiveness in a Real-Life Study. ( de Vries, C; Haerden, Y; Lins, R, 2017) |
| " It was concluded that the formulated nifedipine pulsatile dosage form could be useful in the treatment of hypertension." | 3.85 | Development and Characterization Pulsatile Microspheres of Nifedipine for Hypertension. ( Gupta, GD; Taneja, R, 2017) |
| "Doppler ultrasound and myography were utilised to assess uterine artery functional and structural changes pre-pregnancy and at gestational day 18 in SHRSP (untreated and nifedipine treated) and in the normotensive Wistar-Kyoto (WKY) rat." | 3.83 | Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat. ( Beattie, E; Delles, C; Graham, D; Griffin, S; Indahl, M; Morgan, H; Small, HY, 2016) |
| "Nifedipine immediate release (IR) is a short-acting dihydropyridine calcium channel blocker historically used for hypertensive crisis, but its use has decreased because of reports of adverse reactions such as myocardial infarction (MI), arrhythmias, and stroke." | 3.83 | Safety of Immediate-Release Nifedipine. ( Benken, ST; Means, L; Tesoro, EP, 2016) |
| " We therefore investigated the effects of diltiazem on cardiac gene expression in normotensive and hypertensive rats with left ventricular hypertrophy and compared the results with our previous findings on verapamil and nifedipine." | 3.83 | Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects. ( Borlak, J; Zwadlo, C, 2016) |
| "To measure the plasma concentrations of adrenomedullin (ADM),atrial natriuretic peptide (ANP), and brain natriuretic peptide (BNP), and investigate their pathophysiological functions in patients with primary aldosteronism (PA)." | 3.81 | Pathophysiological functions of adrenomedullin and natriuretic peptides in patients with primary aldosteronism. ( Hu, W; Wang, W; Xu, CG; Zhang, XB; Zhou, PH, 2015) |
| "Atrasentan attenuated the development of hypertension in heterozygous TGRs, but had no effects in Hannover Sprague-Dawley rats." | 3.81 | Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet. ( Dobešová, Z; Kuneš, J; Vaněčková, I; Vernerová, Z; Zicha, J, 2015) |
| " Patients with hypertension (ie, blood pressure [BP] >140/90 mm Hg, or >130/80 mm Hg in patients at high or very high cardiovascular risk) received once-daily nifedipine GITS (30, 60 or 90 mg) in combination with another antihypertensive or as add-on to existing therapy." | 3.81 | Effectiveness of combination therapy with nifedipine GITS: a prospective, 12-week observational study (AdADOSE). ( Dello, Z; Hussain, W; Motaweih, AK; Petri, T; Schmidt, B; Usova, E, 2015) |
| "Nifedipine is a dihydropyridine calcium channel blocker used for the treatment of hypertension in pregnant women." | 3.81 | Analysis of nifedipine in human plasma and amniotic fluid by liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetics in hypertensive pregnant women. ( Carvalho, DM; Cavalli, RC; Duarte, G; Filgueira, GC; Filgueira, OA; Lanchote, VL; Marques, MP; Moisés, EC, 2015) |
| " Using this unique model we investigated effects on AAA formation of the L-type calcium channel blocker nifedipine, in view of the unclear relationship between hypertension and AAA, and unclear mechanisms of aneurysm protective effects of some blood pressure lowering drugs." | 3.81 | Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications. ( Cai, H; Miao, XN; Siu, KL, 2015) |
| "As hypertension (HT) is one of the risk factors for lower urinary tract symptoms, we investigated the effect of an angiotensin II type I receptor blocker, olmesartan, on bladder dysfunction in the spontaneously hypertensive rat (SHR)." | 3.80 | Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress. ( Dimitriadis, F; Kinoshita, Y; Martin, DT; Ohmasa, F; Oikawa, R; Oiwa, H; Saito, M; Satoh, I; Shimizu, S; Tomita, S; Tsounapi, P, 2014) |
| " In the first study, we investigated the effects of a 3-month treatment with an ARB with additional PPARγ agonist activity, telmisartan, or with a dihydropyridine calcium channel blocker, nifedipine, on insulin signalling in patients with mild-moderate essential hypertension." | 3.80 | Effect of antihypertensive treatments on insulin signalling in lympho-monocytes of essential hypertensive patients: a pilot study. ( Agabiti Rosei, E; De Ciuceis, C; Di Gregorio, J; Donini, C; Flati, V; La Boria, E; Pasini, E; Petroboni, B; Porteri, E; Rizzoni, D; Rossini, C; Rufo, A, 2014) |
| "6 years, 54% men), a subgroup of 544 participants in the calcification side arm of the INSIGHT (International Nifedipine Study Intervention as Goal for Hypertension Therapy)." | 3.79 | Progression of coronary artery calcification is associated with long-term cardiovascular events in hypertensive adults. ( Apter, S; Grossman, C; Grossman, E; Morag-Koren, N; Motro, M; Shemesh, J, 2013) |
| "In case of non-treated hypertension several medications and their combinations were studied (captopril, and moxonidine as such, captopril + nifedipine, captopril + moxonidine)." | 3.79 | [The efficacy of antihypertension drugs and their combinations in the non-treated hypertension]. ( Chiritso, MM; Grishin, OV; Ruksin, VV, 2013) |
| "Nifedipine as a pharmacologic agent for treating hypertension and angina pectoris has been available worldwide since the early 1980's." | 3.78 | Once daily nifedipine: the formulation dictates the pharmacokinetic characteristics and the therapeutic responses. ( Elliott, HL; Meredith, PA; Toal, CB, 2012) |
| "In this case report, we describe the clinical course over a 14-year follow-up in a 47-year-old diabetes patient with severe chronic periodontitis and nifedipine-induced gingival overgrowth." | 3.78 | Clinical case report of long-term follow-up in type-2 diabetes patient with severe chronic periodontitis and nifedipine-induced gingival overgrowth. ( Fujinami, K; Shibukawa, Y; Yamashita, S, 2012) |
| "To describe the case of treatment with amlodipine in a poorly controlled hypertension in a pediatric patient diagnosed with tricodistrofia." | 3.78 | Amlodipine in pediatric patient with uncontrolled multifactorial hypertension. Formulation of amlodipine oral suspension. ( Arias Santos, I; Lago Rivero, N; Paradela Carreiro, A, 2012) |
| "To compare the clinical efficacy and safety of sublingual nifedipine and intravenous urapidil in the treatment of acute postoperative hypertension." | 3.77 | [Efficacy of sublingual nifedipine and intravenous urapidil for treatment of acute postoperative hypertension]. ( Lou, N; Wang, DF; Wang, Z, 2011) |
| "To determine the effect of combination of edible oils on blood pressure, anthropometric parameters, lipid profile, lipid peroxidative markers, antioxidant status and electrolytes in drug (nifedipine) taking patients with hypertension." | 3.77 | Effect of combination of edible oils on blood pressure, lipid profile, lipid peroxidative markers, antioxidant status, and electrolytes in patients with hypertension on nifedipine treatment. ( Al-Numair, KS; Chandramohan, G; Kalaiarasi, P; Pugalendi, KV; Rao, RK; Sudhakar, B, 2011) |
| "Long-acting nifedipine GITS/OROS, alone or in combination with other antihypertensive agents, provides effective and well tolerated treatment of hypertension in a broad spectrum of patients routinely seen in day-to-day clinical practice." | 3.77 | Efficacy and tolerability of long-acting nifedipine GITS/OROS monotherapy or combination therapy in hypertensive patients: results of a 12-week international, prospective, multicentre, observational study. ( El Maksod, A; Hung, KY; Ningling, S; Ueng, KC; Yuehui, Y, 2011) |
| "Drug-induced gingival overgrowth (DIGO) is a significant problem for periodontologists and this side effect is frequently associated with three particular drugs: phenytoin, cyclosporin A and nifedipine." | 3.76 | Non-surgical treatment of gingival overgrowth induced by nifedipine: a case report on an elderly patient. ( Cabral, PA; Cimões, R; de Carvalho Farias, B; Gusmão, ES; Jamelli, SR, 2010) |
| "Two hundred eighty-six outpatients prescribed three different CCBs (benidipine [CAS 91599-74-5], amlodipine [CAS 111470-99-6] and controlled release nifedipine (nifedipine CR) [CAS 21829-25-4]) for hypertension in combination with ARBs during a 4-year period were registered in a retrospective comparative study." | 3.76 | Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study. ( Futenma, A; Imai, H; Kimura, Y; Maeda, K; Miura, N; Suga, N; Yamada, H, 2010) |
| "Nifedipine may inhibit vascular remodeling and improve vascular function by selective activation of PPARgamma through the activation of Cu/ZnSOD in hypertension." | 3.76 | Nifedipine activates PPARgamma and exerts antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP. ( Guo, F; Hashimoto, R; Itoh, S; Kishi, H; Kobayashi, S; Matsuzaki, M; Umeji, K; Umemoto, S, 2010) |
| "Combination use of Jimaitong and nifedipine has synergistic effects on anti-hypertension in spontaneously hypertensive rats." | 3.76 | [Effect of Jimaitong tablet combined with nifedipine on blood-pressure and mechanisms investigation in spontaneously hypertensive rats]. ( Chen, S; Fang, Q; Lv, G; Lv, L; Wu, X; Yu, S, 2010) |
| " The pharmacokinetics of verapamil and of one of its metabolites, norverapamil, is changed after multiple oral dosing as has been described in patients with supraventricular tachyarrhythmias, angina pectoris or in patients with essential hypertension." | 3.76 | Pharmacokinetics of calcium channel blocking agents. ( Anderson, P, 1986) |
| "A 54-year-old woman started to take nifedipine orally for hypertension on February 18, 2006." | 3.75 | [A case of Sjögren syndrome with nifedipine-induced pneumonia]. ( Chida, E; Nagashima, H; Ogawa, J; Yamauchi, K, 2009) |
| "A 43 year old man with HIV and HCV infection and liver cirrhosis developed fatal lactic acidosis within five days from starting nifedipine for arterial hypertension." | 3.75 | Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals. ( Mian, P; Moling, O; Pagani, L; Pristerà, R; Rimenti, G; Spoladore, G; Vedovelli, C, 2009) |
| "Nifedipine is a therapeutic drug in acute attacks of hypertension because of its rapid absorption from oral mucosa." | 3.75 | Antihypertensive role of glossopharyngeal nerve stimulation by nifedipine using as calcium channel blocking agent in hypertension: an experimental study. ( Atalay, C; Aydin, MD; Aydin, N; Bayram, E; Gundogdu, C; Halici, Z; Kotan, D; Ulvi, H, 2009) |
| "Electron paramagnetic resonance (EPR) spectroscopy was used to investigate the gamma-radiation damage in the crystalline powder form of nine calcium channel blockers from the 1,4-dihydropyridine derivatives, which are in clinical use for treatment of arteria hypertension and ischemic heart disease." | 3.74 | The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state. ( Mielcarek, J; Naskrent, M, 2007) |
| "Nifedipine GITS proved to be effective and well tolerated for the treatment of hypertension in 3003 Chinese patients." | 3.74 | Efficacy and safety of nifedipine GITS in Chinese patients with hypertension--a post-marketing surveillance study. ( Chen, H; He, Q; Huo, Y; Landen, H; Ma, J; Zhang, J, 2007) |
| "Nifedipine GITS proved to be effective and well tolerated for the treatment of hypertension in 7395 Chinese patients under normal daily practice conditions." | 3.74 | Efficacy and safety of nifedipine GITS in Asians with hypertension: results of a post-marketing surveillance study in China. ( Guozhang, L; Junren, Z; Landen, H; Ningling, S; Runlin, G; Tingjie, Z; Weizhong, Z, 2007) |
| "Losartan reduced significantly the systolic blood pressure as well as the aorta and left ventricular hypertrophy." | 3.74 | Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats. ( Tinel, H, 2007) |
| " Chronic captopril treatment of SHR prevented hypertension development by suppression of their sympathetic vasoconstriction including its nifedipine-sensitive component, but failed to influence enhanced NE-induced arterial contractions or increased relaxation to nifedipine in vitro." | 3.74 | Nifedipine-sensitive noradrenergic vasoconstriction is enhanced in spontaneously hypertensive rats: the influence of chronic captopril treatment. ( Dobesová, Z; Kunes, J; Lísková, S; Paulis, L; Pintérová, M; Zicha, J, 2007) |
| "Hypertension in an 83-year-old woman with early Alzheimer disease was treated with a calcium channel blocker, nilvadipine, for 3 months." | 3.74 | Effect of nilvadipine on regional cerebral blood flow in a patient with early Alzheimer disease. ( Araki, N; Imabayashi, E; Kuji, I; Matsuda, H; Ohkubo, T; Shimazu, K, 2008) |
| "Among the L-type calcium channel blockers (CCBs), particularly dihydropyridines like nifedipine [1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid dimethyl ester], a common adverse effect is vasodilatory edema." | 3.74 | The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay. ( Black, N; Dhamija, S; Kowala, MC; Liachenko, S; Madore, S; Major, TC; Morenko, B; Okerberg, C; Sobocinski, G; Tinholt, P, 2008) |
| "Study aim was assessment of clinical efficacy of mono therapy with nifedipine SR/GITS and combination of nifedipine SR/GITS and bisoprolol as well as investigation of functional state of sympathoadrenal system (SAS) in pregnant women with arterial hypertension." | 3.74 | [Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol]. ( Brytkova, IaV; Bukhonkina, IuM; Pavlova, LN; Striuk, RI, 2008) |
| " She would like to know whether she can continue using metformin during the pregnancy and also is concerned about the effect of the gastric bypass surgery." | 3.74 | A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery. ( Coustan, DR, 2008) |
| "A 77-year-old male with uncontrollable hypertension developed shock, heart block, and multiorgan failure 2 days after clarithromycin was added to his antihypertensive treatment (nifedipine, captopril, doxazosin)." | 3.73 | Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock. ( Cortiñas-Sáez, M; Cuartero-del-Pozo, AB; Gerónimo-Pardo, M; Jiménez-Vizuete, JM; Peyró-García, R, 2005) |
| "It is generally agreed that short acting calcium channel blockers (CCB) as nifedipine are not safe as the reflex increase in sympathetic activity and thus, their use in hypertension (HTN) is questionable." | 3.73 | Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine. ( Sweileh, WM, 2005) |
| "Short-acting nifedipine is still advocated for use in children with severe hypertension, but is no longer recommended for use in adults because of adverse effects from rapid blood pressure reduction." | 3.73 | Ventricular arrhythmia following short-acting nifedipine administration. ( Castaneda, MP; Del Rio, M; Flynn, JT; Walsh, CA; Woroniecki, RP, 2005) |
| "The effect of a nifedipine induced reduction in systemic blood pressure on pulse amplitude (PA) as assessed with pneumotonometry and fundus pulsation amplitude (FPA), as measured with laser interferometry was investigated in 16 untreated patients with moderate to severe systemic hypertension (mean arterial pressure 123 (SD 12) mm Hg)." | 3.73 | Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension. ( Bayerle-Eder, M; Gasic, S; Kolodjaschna, J; Polska, E; Schmetterer, L; Wolzt, M, 2005) |
| "Nifedipine OROS proved to be effective and well tolerated for the treatment of hypertension in 2044 Chinese patients." | 3.73 | Nifedipine OROS in Chinese patients with hypertension--results of a post-marketing surveillance study in Taiwan. ( Chen, ZC; Hu, SA; Hung, KC; Hung, YJ; Landen, H; Ueng, KC; Yeh, PS, 2005) |
| "This study was designed to examine the hypothesis that a calcium channel blocker nifedipine (CCB) could enhance the cardioprotective effect of an angiotensin-ll receptor blocker candesartan (ARB) in the treatment for heart failure." | 3.73 | Nifedipine enhances the cardioprotective effect of an angiotensin-II receptor blocker in an experimental animal model of heart failure. ( Hayashi, T; Horimoto, H; Inamoto, S; Kitaura, Y; Mieno, S; Mori, T; Okabe, M; Okuda, N, 2005) |
| " In the present study the hyperbaric index (hyperBI) and hypobaric index (hypoBI) were compared with the mean blood pressure (BP) over 24 h to evaluate the antihypertensive effect of long-acting nifedipine on essential hypertension." | 3.73 | Chronobiological analysis by ambulatory blood pressure monitoring of the hyperbaric and hypobaric indexes for evaluation of the antihypertensive effect of long-acting nifedipine. ( Imamoto, S; Ito, T; Iwano, K; Kanae, K; Koga, A; Kunoh, M; Miyazaki, H; Mochizuki, S; Ohsawa, S; Satoh, C; Seki, S; Takeda, S; Taniguchi, M, 2005) |
| "The Ca(2+) antagonists nifedipine has been used for more than three decades to treat hypertension, but its effects on the transcriptional regulation of cardiac genes are basically unknown." | 3.73 | Nifedipine represses ion channels, transporters and Ca(2+)-binding proteins in hearts of spontaneously hypertensive rats. ( Borlak, J; Zwadlo, C, 2006) |
| "To assess the variation of body composition at term in patients with normal pregnancy and patients with gestational hypertension (GH) treated with nifedipine." | 3.72 | Nifedipine-induced changes in body composition in hypertensive patients at term. ( Altomare, F; Andreoli, A; Arduini, D; De Lorenzo, A; Larciprete, G; Novelli, G; Valensise, H; Vasapollo, B, 2003) |
| "MCAs from srSHR and prestroke SHRSP exhibited pressure-dependent constriction and constricted in response to vasopressin or serotonin in the presence of nifedipine or the absence of [Ca2+]o." | 3.72 | Stroke development in stroke-prone spontaneously hypertensive rats alters the ability of cerebrovascular muscle to utilize internal Ca2+ to elicit constriction. ( Smeda, JS, 2003) |
| "The prototype 1,4-dihydropyridine (1,4-DHP) nifedipine, indicated for the management of hypertension and angina pectoris, has drawbacks of rapid onset of vasodilating action and a short half-life." | 3.72 | Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes. ( Bohlooli, S; Grant, MH; Mahmoudian, M; Skellern, GG; Tettey, JN, 2004) |
| "MCAs from DSS rats after stroke constricted in response to vasopressin but were unable to constrict in response to pressure or PDB in the presence of nifedipine, whereas those from DSS rats before stroke and from DSR rats constricted in response to all the stimuli." | 3.71 | Cerebrovascular alterations in pressure and protein kinase C-mediated constriction in Dahl salt-sensitive rats. ( Payne, GW; Smeda, JS, 2002) |
| "Two cases are reported in which depression was associated with the use of calcium channel blocker, nifedipine." | 3.71 | Depression--an adverse event with nifedipine. ( Gandhi, RR; Gohel, DR; Oza, YK; Patalia, AH; Rathod, NR, 2002) |
| " In anaesthetized Wistar rats, baroreceptor-unloading-mediated reflex activation of SNS, as indicated by tachycardia and increase of plasma catecholamines, was observed after mean arterial pressure (MAP) was decreased by 15 mmHg during 4-h administration of nifedipine, a CCB." | 3.71 | Resetting baroreceptors to a lower arterial pressure level by enalapril avoids baroreflex mediated activation of sympathetic nervous system by nifedipine. ( Wang, Z; Zhang, W, 2001) |
| "To evaluate the use of short-acting nifedipine for treatment of severe hypertension in children." | 3.71 | The use of short-acting nifedipine in pediatric patients with hypertension. ( Blaszak, RT; Ellis, EN; Savage, JA, 2001) |
| "The objective of the present study was to evaluate the efficacy and safety of a therapeutic interchange between high-dose calcium channel blocker therapy and a fixed-dose combination of amlodipine/ benazepril (Lotrel; Novartis Pharmaceuticals, USA) in patients with moderate to severe hypertension." | 3.71 | Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension. ( Faulkner, M; Hilleman, DE; Reyes, AP; Wurdeman, RL, 2001) |
| "The main objective of this study was to evaluate well-being and physical activity of 248 hypertensive patients, including 177 females, who had previously been included in the Latin-American Study on Lacidipine in Hypertension (LASTLHY)." | 3.71 | Semipersonalized psychological evaluation of quality of life in hypertensive patients during a trial with two calcium antagonists: a multicenter Latin-American Study (LASTLHY). ( Alcocer, L; Armas-Hernández, MJ; Armas-Padilla, MC; Hernández-Hernández, R; Lezama, E; Velasco, M, 2001) |
| "Short-acting nifedipine (SA-NIF) is widely prescribed for acute hypertension (HTN) in children despite reports of ischemic complications in adults." | 3.71 | Adverse neurologic events associated with rebound hypertension after using short-acting nifedipine in childhood hypertension. ( Feldman, HI; Kasner, SE; Leonard, MB; Schulman, SL, 2001) |
| "The three treatments regressed cardiac hypertrophy and normalized sodium/hydrogen ion exchange exchange activity in SHR, and losartan was the most effective treatment for reversing cardiac hypertrophy, despite producing effects on blood pressure and sodium/hydrogen exchange activity similar to that of other antihypertensive drugs." | 3.71 | Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats. ( Alvarez, BV; Cingolani, HE; De Hurtado, MC; Ennis, IL, 2002) |
| "In 21 pregnancies complicated by pregnancy-induced hypertension (PIH) which was treated by antihypertensive drugs (labetalol, nifedipine), fetal behavioural recordings (quiet state, C1F; active state, C2F; no coincidence, NOC) and Doppler measurements of blood flow velocity in the umbilical artery (UA) (resistance index, RI) were made on two occasions (27-32 and 33-36 weeks of gestation)." | 3.70 | Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states. ( Bruschettini, PL; Gazzolo, D; Russo, A; Santi, F; Scopesi, F; Visser, GH, 1998) |
| " Nitroglycerin was named as first choice only for pulmonary oedema or myocardial infarction." | 3.70 | [Diagnostic and therapeutic procedures by doctors for patients in a hypertensive crisis. An inquiry in 56 internal medicine clinics]. ( Grieshaber, M; Schwietzer, G; Stahl, RA; Wenzel, UO, 1998) |
| "To assess the effects of a vasodilatory beta-adrenoceptor blocker, nipradilol, and a long-acting Ca channel blocker, barnidipine, on insulin sensitivity." | 3.70 | Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension. ( Awata, T; Inaba, M; Katayama, S; Kosegawa, I; Morita, T, 1998) |
| "Nifedipine is a Ca-antagonist drug that reduces contractility of vascular smooth muscle, and is used in the treatment of arterial hypertension and of stable and vasospastic angina." | 3.70 | Nifedipine and extracellular water in dialysis arterial hypertension. ( Carpinteri, G; Iannetti, E; Trovato, GM, 1998) |
| "Oral combinations of nifedipine and atenolol are widely used in the treatment of hypertension, proving particularly effective when the atenolol is released immediately and the nifedipine is released in a sustained manner." | 3.70 | Development of tablets for controlled joint release of nifedipine and atenolol. ( Concheiro, A; Gómez-Amoza, JL; Iglesias, R; Martínez-Pacheco, R; Souto, C; Taboada, C, 1998) |
| "To evaluate 24-hour blood pressure control and frequency of adverse effects in patients with mild to moderate hypertension switched from nifedipine gastrointestinal therapeutic system (Nif-GITS) to nifedipine coat core (Nif-CC)." | 3.70 | Comparison of 24-hour ambulatory blood pressure data in hypertensive patients switched from nifedipine-GITS to nifedipine-CC. ( Hilleman, DE; Lucas, BD; Mohiuddin, SM; Mooss, AN; Ryschon, KL; Wurdeman, RL, 1999) |
| "Ninety patients, 50 males and 40 females, and their ages ranged between 42 and 70 years, with severe hypertension were treated by either sublingual verapamil tablets 40 mg (30 patients) or 80 mg (30 patients) or sublingual nifedipine capsules 10 mg (30 patients)." | 3.70 | Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine. ( Al-Waili, NS; Hasan, NA, 1999) |
| "The effects of the Ca2+ channel blockers diltiazem, nifedipine and amlodipine were investigated on both arterial hypertension and myocardial changes induced by chronic blockade of nitric oxide synthesis." | 3.70 | Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat. ( Antunes, E; de Luca, IM; de Nucci, G; de Oliveira, CF; Metze, K; Moreno, H; Nathan, LP; Sucupira, M; Zappellini, A; Zatz, R, 1999) |
| " Although nifedipine-treated patients had a higher prevalence of coronary heart disease diagnosis than diuretic-treated patients (52% versus 35%), their relative risk of mortality was 0." | 3.70 | Mortality in the Jerusalem 70-year-olds longitudinal study: does nifedipine have a role? ( Bursztyn, M; Ginsberg, G; Maaravi, Y; Spilberg, O; Stessman, J, 1999) |
| "We studied 34 older, nonsmoking patients (mean age 74 +/- 5 years) with uncomplicated hypertension before and after the normalization of blood pressure (BP) was achieved with the angiotensin-converting enzyme inhibitor quinapril alone or in combination with the Ca2+ antagonist nifedipine." | 3.70 | Platelet hyperactivity in hypertensive older patients is controlled by lowering blood pressure. ( Di Veroli, C; Gazzaniga, PP; Lenti, L; Marigliano, V; Pignatelli, P; Pulcinelli, FM; Riondino, S, 1999) |
| " Nifedipine treatment in both young and adult hypertensive rats prevented the V3 rise due to hypertension and to the aging process." | 3.70 | Age-related difference in cardiac adaptation to chronic hypertension in rats, with and without nifedipine treatment. ( Malhotra, A; Nakouzi, A; Pathak, D; Raizada, V; Skipper, B, 1999) |
| "Similar lesion topography which resembled an inverted fir tree in two patients with nifedipine-related pemphigus vulgaris is described." | 3.70 | Lesion topography in two cases of nifedipine-related pemphigus. ( Bialy-Golan, A; Brenner, S; Golan, H; Ruocco, V, 1999) |
| " To test the method in a clinical application, peripheral vascular resistance was determined by the noninvasive method before and after administration of nifedipine in 6 patients with essential hypertension." | 3.70 | Noninvasive, continuous evaluation of peripheral vascular resistance in humans. ( Honda, N; Horita, M; Hoshiba, Y; Kitagawa, I; Masuya, H; Matsuura, K; Morise, T; Shinzato, R; Takekoshi, N, 2000) |
| "One hundred patients with hypertension who were receiving amlodipine." | 3.70 | Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers. ( Beckey, NP; Korman, L; Parra, D, 2000) |
| " Endothelin-1 (ET-1), one of the endogenous pathological humoral factors of cardiovascular diseases such as hypertension and heart failure, has a strong vasoconstrictive action and could induce hypertension and cardiac hypertrophy." | 3.70 | Possible involvement of endothelin-1 in cardioprotective effects of benidipine. ( Akashi, T; Harada, M; Hosoya, T; Ikeda, K; Nakagawa, O; Nakao, K; Tojo, K; Tokudome, G, 2000) |
| " After treatment with a sustained release formulation of the calcium antagonist, nifedipine, their blood pressure returned to normal, anal tone was reduced, and the frequency and intensity of anal pain was suppressed." | 3.69 | Hereditary proctalgia fugax and constipation: report of a second family. ( Celik, AF; Donnelly, TC; Katsinelos, P; Khan, MI; Read, NW, 1995) |
| " In order to investigate further whether the increased sensitivity to inhibition by nifedipine of the responses to noradrenaline of aortae from spontaneously hypertensive stroke-prone (SHRSP) rats is related to the development of the hypertension, we have compared the sensitivity to noradrenaline, potassium chloride (KCl) and nifedipine of aortae from SHRSP and control (Wistar-Kyoto) WKY rats of different age groups (young: 3-5 weeks, and adult: 13-16 weeks)." | 3.69 | The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age. ( Iwanov, V; Jiang, GC; Moulds, RF, 1995) |
| "We investigated the regression of left ventricular (LV) hypertrophy with long-term treatment of nifedipine in patients with systemic hypertension." | 3.69 | Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension. ( Maeda, M; Nakano, T; Oonishi, T; Teramura, S; Yamakado, T, 1994) |
| " The atherogenic significance of Ca ions and arterial Ca overload was examined under the influence of nicotine, oxidatively modified low-density lipoproteins, spontaneous hypertension, and an elevated extracellular Ca concentration or vitamin D3." | 3.69 | Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations. ( Czirfuzs, A; Fleckenstein-Grün, G; Frey, M; Matyas, S; Thimm, F, 1994) |
| "Nifedipine was administered to 49 pregnant women with gestational hypertension as first-line therapy, and were longitudinally studied as paired observations for 3 or 10 day intervals of treatment with nifedipine until delivery." | 3.69 | The use of nifedipine as first-line hypotensive therapy in gestational hypertension. ( Caruso, A; De Carolis, MP; De Carolis, S; Ferrazzani, S; Mancinelli, S; Romano, D, 1994) |
| "A 66-year-old hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure was treated by adding enalapril, an angiotensin converting enzyme inhibitor, to the furosemide and nifedipine regimen because of an insufficient antihypertensive response for 1 month." | 3.69 | Reversible hyperkalemia during antihypertensive therapy in a hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure. ( Azukizawa, S; Kaneko, M; Kigoshi, T; Matsui, A; Morimoto, S; Nakano, S; Uchida, K, 1994) |
| " Nifedipine is often used to control hypertension in kidney graft recipients." | 3.69 | Nifedipine aggravates cyclosporine A-induced gingival hyperplasia. ( Albers, N; Beier, C; Bohnhorst, B; Bökenkamp, A; Brodehl, J; Offner, G, 1994) |
| "We assessed the action of nifedipine on vascular reactivity to angiotensin II (AII) in pregnant women at risk for hypertension." | 3.69 | Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women. ( Conti, C; Garzetti, GG; Rezai, B; Romanini, C; Tranquilli, AL, 1994) |
| "The effect of a single 20 mg sublingual dose of nifedipine on function of proximal tubule of nephron in patients with essential hypertension was studied by measuring changes in renal excretion of water, sodium, uric acid and beta-2-microglobulin (B2m) after nifedipine administration." | 3.69 | [Effect of nifedipine on proximal tubular function in patients with essential hypertension]. ( Pupek-Musialik, D; Rutz, A; Tykarski, A, 1994) |
| "To clarify the effect of the calcium antagonist Nifedipine and the ACE inhibitor Enalapril on cardiac autonomic activity, power spectral analysis of heart rate variability (PSA) was conducted in 39 elderly patients with essential hypertension (mean age: 63: +/- 11 years) before and after treatment." | 3.69 | [Effect of nifedipine and enalapril on cardiac autonomic activity in elderly hypertensive patients]. ( Matsubayashi, K; Okabayashi, J; Ozawa, T; Sato, T, 1994) |
| "The authors examined the efficacy and safety of the combination of verapamil and nifedipine in the control of hypertension." | 3.69 | Verapamil and nifedipine in combination for the treatment of hypertension. ( Bottini, PB; Carr, AA; Kaesemeyer, WH; Prisant, LM, 1994) |
| " Study 1: A long-term (4 weeks) treatment with slow-release nifedipine (Nif), 40-60 mg/day, was performed in 9 in-patients with essential hypertension (EHT)." | 3.69 | [Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism]. ( Iimura, O; Shimamoto, K; Yokoyama, T, 1995) |
| " Hypertension was treated by nifedipine retard and occasionally by furosemide." | 3.69 | Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation. ( Alivanis, P; Dioudis, C; Goutsaridis, N; Grekas, D; Kalevrosoglou, I; Papoulidou, F; Tourkantonis, A, 1995) |
| "To evaluate the effect of acute blood pressure (BP) changes on the myocardial perfusion in hypertensives, 10 patients with and 10 patients without left ventricular hypertrophy (LVH) were examined with 99TCm-Sestamibi scintigraphy at rest and after acute pharmacological BP reduction using nifedipine and captopril." | 3.69 | Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy. ( Berglund, G; Boström, PA; Diemer, H; Lilja, B; Mansour, P; Mattiasson, I; Nehoum, A, 1995) |
| "Our purpose was to evaluate the hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies." | 3.69 | Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies. ( Hogg, BB; Newman, RB; Scardo, JA; Vermillion, ST, 1996) |
| "The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats." | 3.69 | Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996) |
| " The effect of a 2-week treatment with nifedipine, captopril and prazosin upon glycaemia, serum insulin (IRI) and C-peptide (CP) following oral and intravenous glucose load were investigated in three groups, each including 10 non-diabetic patients with essential hypertension (h) and 10 hypertensive type 2 (non-insulin-dependent) diabetics (h + d), aged 32-63 years." | 3.69 | Effect of nifedipine, captopril and prazosin on secretory function of pancreatic beta-cells in hypertensive patients with type-2 (non-insulin-dependent) diabetes and in hypertensive non-diabetics. ( Czyzyk, A; Jasik, M; Kasperska-Dworak, A, 1996) |
| "Despite the absence of an approved Food and Drug Administration (FDA) indication, the use of oral or "sublingual" nifedipine for hypertension in the hospitalized patient has become an increasingly common practice." | 3.69 | "Inappropriate" physician habits in prescribing oral nifedipine capsules in hospitalized patients. ( Mansoor, GA; Rehman, F; White, WB, 1996) |
| " Mibefradil treatment resulted in lower blood pressure, reduced cardiac hypertrophy, near-normal structure of conduit and small arteries and lower endothelin-1 mRNA abundance." | 3.69 | Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats. ( Li, JS; Schiffrin, EL; Sventek, P, 1996) |
| " We have previously described an increased sensitivity to inhibition by nifedipine of noradrenaline-induced contractures of blood vessels in hypertension." | 3.69 | Relationship between nifedipine sensitivity of aortae and blood pressure of stroke-prone spontaneously hypertensive rats. ( Iwanov, V; Jiang, GC; Moulds, RF, 1996) |
| "Nifedipine is a commonly used agent in treating hypertension and angina because of its vasodilator properties." | 3.69 | Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis. ( Cunningham, SK; Fiad, TM; Hayes, FJ; McKenna, TJ, 1997) |
| "The objective of this study was to clarify potential differences in the metabolism of glucose and lipids in a long-term treatment (for 5 years) for hypertension among nifedipine-retard and captopril in young, nonobese hypertensive men (HT)." | 3.69 | Metabolic effects of long-term treatments with nifedipine-retard and captopril in young hypertensive patients. ( Masuo, K; Mikami, H; Ogihara, T; Tuck, ML, 1997) |
| "To investigate the effect of 7 to 14 days of therapy with nifedipine (sustained-release preparation) on the 24-hour blood pressure patterns of pregnant women with pre-eclampsia or chronic hypertension, and to test the utility of blood pressure monitoring in modulating the timing and dosage of the drug." | 3.69 | 24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy. ( Benedetto, C; Carandente, F; Chiarolini, L; Giarola, M; Maulà, V; Zonca, M, 1997) |
| "This study was conducted to investigate the effects of long-term administration of a calcium-channel antagonist (nifedipine) and a beta-blocker (acebutolol) on physical fitness in men with mild hypertension." | 3.69 | Effects of long-term antihypertensive therapy on physical fitness of men with mild hypertension. ( Doba, N; Hinohara, S; Kajiwara, N; Kanmatsuse, K; Kushiro, T; Tomiyama, H; Yamashita, M; Yoshida, H, 1997) |
| " Description of their management, usage of nifedipine, and pregnancy outcome." | 3.69 | Sublingual nifedipine in human pregnancy. ( Gallery, ED; Györy, AZ, 1997) |
| "Antihypertensive efficacy of the calcium channel blocker, nilvadipine, was investigated in 21 patients with essential hypertension in relation to the intracellular sodium concentration ([Na]i) in erythrocytes and clinical variables, such as age, body weight, pretreatment blood pressure and plasma renin activity." | 3.68 | Erythrocyte sodium cannot predict hypotensive effects of calcium channel blockers. ( Ishibashi, K; Ishida, T; Ishida-Kainouchi, M; Kajiyama, G; Kanbe, M; Matsuura, H; Okura, Y; Oshima, T; Ozono, R; Watanabe, M, 1993) |
| "Nifedipine antihypertensive effect was evaluated in 20 patients with essential hypertension." | 3.68 | [A method for determining individual nifedipine sensitivity in treating hypertension patients]. ( Atakhanov, ShE; Baliakina, EV; Gabbasov, ZA; Iurenev, AP; Popov, EG, 1993) |
| " DESIGN OF STUDIES: Mean cerebral circulation parameters were studied in chronic stroke patients with hypertension and treated acutely or chronically (2 weeks) with nicardipine or nifedipine retard." | 3.68 | Effects of dihydropyridines on cerebral blood vessels. ( Hashimoto, H; Kuriyama, Y; Nagatsuka, K; Omae, T; Sawada, T, 1993) |
| "Acute effects of Nifedipine, a calcium channel blocking agent (CCBA), on central haemodynamics in patients with severe hypertension and angiographically proved coronary artery disease (CAD) has been studied using Nuclear Ventriculography (MUGA)." | 3.68 | Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease. ( Bhatia, ML; Jangid, DR; Kasliwal, RR; Trehan, N, 1993) |
| "Patients undergoing kidney transplantation often suffer from essential hypertension and coronary artery disease, for which perioperative treatment with nifedipine proved to be effective." | 3.68 | [Anesthesia for renal transplantation: continuous neuromuscular blockade with atracurium and the management of intraoperative hypertension with nifedipine]. ( Blobner, M; Felber, AR; Gögler, S; Jelen, G; Jelen-Esselborn, S, 1993) |
| "The effect of rectal administration of nifedipine for the management of intraoperative hypertension was studied in 12 adult neurosurgical patients, physical status II and III." | 3.68 | Rectal nifedipine for the management of intraoperative hypertension. ( Gaur, A; Kaushik, S; Pande, RK, 1993) |
| "The aim was to determine if long term treatment with nifedipine or nisoldipine affects structural remodelling of cardiac myocytes and is effective in attenuating or preventing reparative and reactive myocardial fibrosis in essential hypertension." | 3.68 | Cardiac structural remodelling after treatment of spontaneously hypertensive rats with nifedipine or nisoldipine. ( Campbell, SE; Kazda, S; Rakusan, K; Turek, Z, 1993) |
| " This study evaluated the influence of aging, superimposed chronic hypertension on aging, and treatment with nifedipine on cardiac myosin isozyme proportions." | 3.68 | Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine. ( Blomquist, TM; Minser, R; Pathak, D; Raizada, V; Woodfin, B, 1993) |
| "Thirteen patients with established hypertension underwent radionuclide ventriculography before and after nifedipine administration." | 3.68 | Role of left ventricular regional nonuniformity in hypertensive diastolic dysfunction. ( Arakawa, K; Ikeda, M; Nakashima, Y; Nii, T, 1993) |
| "Effects of Ca ion channel blockers, nicardipine, diltiazem and nifedipine on intraoperative hypertension were evaluated clinically in ninety surgical patients who received various surgical procedures under total intravenous anesthesia with droperidol, fentanyl and ketamine." | 3.68 | [Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension]. ( Hashimoto, Y; Hirota, K; Ishihara, H; Koh, H; Matsuki, A; Takagi, H, 1993) |
| "In 212 cyclosporine-treated renal transplant recipients with stable graft function at 1 year and with potential follow-up of 5 years the prevalence of arterial hypertension was 81." | 3.68 | Hypertension after renal transplantation. ( Angelini, C; Aroldi, A; Braga, M; Montagnino, G; Ponticelli, C; Tarantino, A, 1993) |
| "The nifedipine gastrointestinal therapeutic system (GITS) was recently approved for use in the treatment of angina and hypertension." | 3.68 | P&T Committee review of nifedipine GITS: new modality for angina and hypertension. ( Horn, J; Krakoff, L; Vetrovec, G; Weintraub, M, 1990) |
| "Ketanserin and calcium antagonists are frequently used for the treatment of arterial hypertension in the elderly." | 3.68 | [Cardiac interactions between ketanserin and the calcium antagonist nifedipine]. ( Alberio, L; Beretta-Piccoli, C; Koch, P; Tanzi, F; Zehender, M, 1992) |
| "The antihypertensive effect of slow release nifedipine (CAS 21829-25-4) tablets (20 mg, Adalat) administered once or twice daily was studied in patients with essential hypertension of WHO stage I or II." | 3.68 | Effect of slow release nifedipine tablets in patients with essential hypertension. ( Abe, K; Hashimoto, J; Imai, Y; Minami, N; Munakata, M; Sakuma, H; Sakuma, M; Sasaki, S; Sekino, H; Watanabe, N, 1992) |
| "The effect of treatment of hypertension with nifedipine on plasma renin activity, blood serum level of aldosterone in the course of renin test, and cortisol and growth hormone concentrations after stimulation with insulin hypoglycemia was followed during two weeks of treatment in 40 patients with essential hypertension." | 3.68 | [Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension]. ( Kokot, F; Wnuk, R, 1991) |
| " The pressor response to norepinephrine and angiotensin II, as well as several other blood pressure modulating factors, were studied in normal subjects (n = 9) and patients with essential hypertension (n = 10) before and after 8 weeks of treatment with the long-acting dihydropyridine amlodipine." | 3.68 | Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II. ( Beretta-Piccoli, C; Bühler, FR; Donati, L; Heinen, G; Kusch, F, 1992) |
| " With this end in mind, 21 patients with ischemic heart disease and arterial hypertension were divided into three groups of seven subjects each and submitted to different drug treatments with single daily doses: group 1 received isosorbide-5-mononitrate (60 mg), group 2 amlodipine (10 mg), and group 3 a combination of both drugs at the same dosage, for four weeks." | 3.68 | [The association of amlodipine with isosorbide-5-mononitrate in the treatment of ischemic-hypertensive cardiopathy]. ( D'Aprile, N; Faglia, S; Kristodhullo, A; Mondillo, S; Palazzuoli, V, 1992) |
| "The purpose of the present investigation was to study the distensibility of the ascending aorta in patients with arterial hypertension and normal subjects before and after administration of a calcium antagonist, nifedipine." | 3.68 | Ascending aorta distensibility abnormalities in hypertensive patients and response to nifedipine administration. ( Boudoulas, H; Kallikazaros, I; Stefanadis, C; Stratos, C; Toutouzas, P, 1992) |
| "In 40 patients with idiopathic systemic hypertension, skin blood flow was evaluated with laser-Doppler flowmetry, transcutaneous measurements of partial pressure of oxygen (PO2) and partial pressure of carbon dioxide (PCO2), and determination of capillary permeability before and after treatment with nifedipine (10 mg tid for four weeks)." | 3.68 | Microcirculation in systemic hypertension. ( Belcaro, GV; Cesarone, MR; Laurora, G, 1992) |
| "The combination of nifedipine and prazosin was more successful in preventing myocardial damage in 16 patients with hypertension than was nifedipine alone in two other patients with hypertension." | 3.68 | Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus). ( Bawaskar, HS; Bawaskar, PH, 1992) |
| "The aim of this research was to assess whether the antihypertensive therapy with nifedipine, a dihydropyridine calcium-antagonist, is able to control hypertension not only at rest but also during exercise." | 3.68 | [The effect of nifedipine on arterial pressure and exercise tolerance in hypertensive patients]. ( Cherchi, A; Lai, C; Leo, MR; Onnis, E; Orani, E; Sau, F; Seguro, C; Soro, A, 1992) |
| "Haemodynamic responses at rest and during exercise were studied in 18 patients with essential hypertension following long-term treatment with amlodipine." | 3.68 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1992) |
| "To evaluate the role of regional hemodynamics in the anti-hypertensive effect of mepirodipine, a new dihydropyridine-derivative calcium antagonist, we measured systemic, renal, hepatic, and forearm hemodynamics in 10 patients with essential hypertension treated with mepirodipine (15 mg/day) for 4 weeks." | 3.68 | The role of renal hemodynamics in the antihypertensive action of mepirodipine, a new calcium antagonist. ( Fujita, T; Noda, H; Ogata, E, 1992) |
| "The pharmacokinetics of oral nifedipine were studied in 15 women with pregnancy-induced hypertension in the third trimester of pregnancy to determine if the drug's disposition was different from that in nonpregnant patients." | 3.68 | Oral nifedipine pharmacokinetics in pregnancy-induced hypertension. ( Akl, SA; Prevost, RR; Sibai, BM; Whybrew, WD, 1992) |
| " Nifedipine given in therapeutic doses for the treatment of hypertension was associated with a threefold increase in the ED50 for phenylephrine (92 to 277 ng/min; p less than 0." | 3.68 | Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension. ( Blaschke, TF; Ford, GA; Hoffman, BB; Katzir, D, 1991) |
| "The aim of the present study was to define the protective effects of verapamil and nifedipine on mechanical performance and energy and substrate metabolism of the postischemically reperfused myocardium in a chronic pressure overload cardiac hypertrophy model." | 3.68 | Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy. ( Buser, PT; Higgins, CB; Wagner, S; Wikman-Coffelt, J; Wu, S, 1991) |
| "The effects of nifedipine SR and lacidipine on blood pressure, left ventricular (LV) hypertrophy, and diastolic function were evaluated in 15 male patients (mean age of 45 +/- 8 years) with mild-to-moderate hypertension." | 3.68 | Remodeling of left ventricular geometry and function induced by lacidipine and nifedipine SR in mild-to-moderate hypertension. ( Arosio, E; Lechi, A; Montesi, G; Montresor, G; Sheiban, I; Tonni, S, 1991) |
| "7 years, mean +/- SD) received intravenous doses of labetalol, an alpha 1- and beta-adrenergic blocker, on 15 separate occasions for treatment of hypertension." | 3.68 | Intravenously administered labetalol for treatment of hypertension in children. ( Bunchman, TE; Lynch, RE; Wood, EG, 1992) |
| "The prevalence and severity of cough during long-term enalapril treatment were examined by comparing a cohort of 136 hypertensive patients who started treatment with enalapril with consecutive age and sex-matched patients who commenced nifedipine therapy during the same period." | 3.68 | Prevalence of persistent cough during long-term enalapril treatment: controlled study versus nifedipine. ( Foster, G; Ramsay, LE; Yeo, WW, 1991) |
| "In sixteen patients with moderate essential hypertension the effects of 10-day nifedipine treatment on serum uric acid and renal excretion of uric acid were evaluated." | 3.68 | [Uric acid and arterial hypertension. III. Effect of nifedipine on serum uric acid level and its renal excretion in primary arterial hypertension]. ( Tykarski, A, 1991) |
| "The time course of structural and functional parameters using echocardiography and the level of atrial natriuretic factor (ANF) employing immunoradiometric assay were examined in 37 patients with essential hypertension taking a 3-week therapy with nifedipine (corinfar) in doses individually chosen." | 3.68 | [Structural-functional state of the hypertensive heart and atrial natriuretic factor during treatment with nifedipine]. ( Bobrov, VA; Konoshevich, SN; Polivoda, SN; Shershnev, VG, 1991) |
| "We describe 2 cases of severe photosensitivity dermatitis following the use of nifedipine for arterial hypertension." | 3.68 | Photodermatitis due to nifedipine: report of 2 cases. ( Gatti, S; Lomuto, M; Zenarola, P, 1991) |
| "Amlodipine administered once daily (5-10 mg) lowered blood pressure and reduced total peripheral resistance in patients with mild-to-severe essential hypertension without any reflex tachycardia." | 3.68 | Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension. ( Digranes, O; Helland, B; Jordal, O; Lund-Johansen, P; Omvik, P; Stray, T; White, W, 1991) |
| "Thirty patients attending Somerset Hospital Outpatient Department, Cape Town, who were on nifedipine for hypertension or chest pain, were followed up for 6 months after alternative therapy was instituted." | 3.68 | Significant cost-saving with modification of antihypertensive therapy. ( Keeton, GR; Monteagudo, MT, 1991) |
| "In ten patients (age: 47-59 yr) with moderately severe essential hypertension, the humoral and hemodynamic effects of a 4-day therapy with 2 x 75 micrograms clonidine, 2 x 20 mg nifedipine (slow-release), and their combination were investigated and compared with baseline values." | 3.68 | Interactions of clonidine and nifedipine in moderately severe hypertensive patients. ( Hüting, J; Mitrovic, V; Patyna, W; Schlepper, M; von Bruchhausen, V, 1991) |
| "In the present study, 20 patients with both hypertension and stabile angina pectoris were treated twice daily for 6 months with 50 mg atenolol and 20 mg retard-formulation nifedipine." | 3.68 | [Therapy of hypertensive coronary patients. Open long-term study with a combination of atenolol and nifedipine]. ( Lindner, UK, 1991) |
| "In 40 patients (pts) with essential hypertension (EH) the plasma levels of insulin, glucagon, gastrin and prolactin during 2 week therapy with nifedipine were evaluated." | 3.68 | [Essential hypertension. Treatment with nifedipine and levels of insulin, glucagon, gastrin and prolactin]. ( Kokot, F; Wnuk, R, 1991) |
| "The effects of antihypertensive drugs, such as nifedipine, chlorpromazine, reserpine and thiopental on mean arterial blood pressure (ABP), mean intracranial pressure (ICP) and cerebral perfusion pressure (CPP) were studied in 43 patients with systemic hypertension and intracranial hypertension due to hemorrhagic cerebrovascular diseases and other causes." | 3.68 | Effects of antihypertensive drugs on intracranial hypertension. ( Handa, Y; Hayashi, M; Hirose, S; Kawano, H; Kobayashi, H; Nozaki, J, 1991) |
| "The hemodynamic and humoral effects and trough-to-peak 24-hour blood pressure responses of 2 nifedipine formulations, capsules and continuous-release once-daily formulation tablets, were evaluated in 10 patients with mild to moderate essential hypertension." | 3.68 | Hemodynamic comparison of two nifedipine formulations in patients with essential hypertension. ( Frohlich, ED; Ketelhut, R; Losem, CJ; McLoughlin, MJ; Messerli, FH, 1991) |
| "Thirty-nine patients with severe hypertension (diastolic blood pressure greater than 120 mm Hg) predominantly drawn from an inner-city population were placed on nifedipine gastrointestinal therapeutic system (GITS) for long-term treatment to achieve a sustained diastolic blood pressure less than 95 mm Hg." | 3.68 | Sustained calcium channel blockade in the treatment of severe hypertension. A two year experience. ( Ardeljan, M; Geizhals, M; Krakoff, LR; Phillips, RA, 1990) |
| "An attenuation of adrenergic activity during the inhibition of endogenous angiotensin II formation was evaluated by determining plasma norepinephrine concentration after a single oral administration of captopril compared to that after nifedipine in essential hypertension." | 3.68 | Captopril attenuates reflex adrenergic response in essential hypertension. ( Masuyama, Y; Mohara, O, 1991) |
| "The short term or acute intravenous administration of nifedipine has been reported to increase urine flow rate and sodium clearance but does not significantly alter the patient's serum or urine electrolytes as other vasodilators." | 3.68 | [Effects of nifedipine, in primary hypertension, on calcium metabolism and on the excretion of the main urinary electrolytes]. ( Ariano, R; Gnocchi, E; Pecchini, F; Rivetti, V, 1991) |
| "As many as 98 patients suffering from essential hypertension (EH) were examined for the effects of verapamil and nifedipine." | 3.68 | [The hemodynamic reactions of hypertension patients taking the calcium antagonists finoptin and korinfar]. ( Geller, AL; Goldabin, VI; Goloshchapov, OA; Mashin, AA, 1990) |
| "Pharmacodynamics and disposition of amlodipine, a dihydropyridine calcium antagonist, were compared between elderly and young patients with hypertension." | 3.68 | Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition. ( Abernethy, DR; Gutkowska, J; Winterbottom, LM, 1990) |
| "Eight patients with mild to moderate uncomplicated essential hypertension who had been taking nifedipine 20 mg twice daily for at least six weeks." | 3.68 | Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure. ( Buckley, MG; Cappuccio, FP; MacGregor, GA; Markandu, ND; Pevahouse, JB; Sagnella, GA, 1990) |
| "The Ca2(+)-ATPase activity and calmodulin (CaM) of erythrocytes and the effect of nifedipine on them were studied in subjects with essential hypertension (EHT)." | 3.68 | [Changes of Ca2(+)-ATPase and calmodulin in erythrocytes and their responses to nifedipine in essential hypertension]. ( Song, K, 1990) |
| "The short-term effect of 20 mg of oral nifedipine on maternal and fetal hemodynamics was investigated in 12 women with pregnancy-induced hypertension." | 3.68 | Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine. ( Ekblad, UU; Erkkola, RU; Pirhonen, JP, 1990) |
| "This study aimed determining the chronic effects of nifedipine (N) on left ventricular filling in 25 patients (mean age 55) with mild to moderate arterial hypertension." | 3.68 | [Effects of chronic administration of nifedipine on echo-Doppler parameters of left ventricular filling in hypertensive patients]. ( Baccarini, S; Barilli, AL; Bernardini, B; Bigoli, M; Bolognesi, R; Ghirarduzzi, A; Manca, C; Piazza, A; Tomasi, C, 1990) |
| "Clinical, hemodynamic and neurohumoral data are available supporting the validity of a differentiated approach to administration of combined treatment with furosemide, digoxin and calcium antagonists nifedipine and verapamil in advanced-aged patients with hypertension complicated by circulatory disorders." | 3.68 | [Evaluation of the effectiveness of calcium antagonists combined with digoxin and furosemide in hypertension complicated by circulatory insufficiency in elderly patients]. ( Orynchak, MA, 1990) |
| "The hematocrit, hemoglobin, serum total protein and serum albumin concentration increased significantly following sublingual administration of nifedipine in patients with essential hypertension (p less than 0." | 3.68 | Increase in hematocrit by nifedipine in hypertensive patients. ( Ichikawa, S; Murata, K; Sakamaki, T; Takayama, Y, 1990) |
| "This study was undertaken to observe the changes in heart function and evaluate the effects of nifedipine on diastolic function in 70 patients with uncomplicated hypertension by M-mode and Doppler echocardiography." | 3.68 | Effects of nifedipine on diastolic function in hypertensive patients--an echocardiographic study. ( Gao, SY; Hu, ZM; Xiang, SQ, 1990) |
| "Ten patients with essential hypertension (WHO grade I-II) were treated in an open dose-adjustment study with the standard regimen of slow-release nifedipine 20 mg b." | 3.68 | Dose adjustment of nifedipine in hypertensive patients. ( Bacracheva, N; Rietbrock, N; Thuermann, P, 1990) |
| "Pharmacokinetics and pharmacodynamics of nifedipine were studied in 12 patients with renal failure and hypertension, after a single dose and during an 18-week treatment period." | 3.68 | Nifedipine as an antihypertensive drug in patients with renal failure--pharmacokinetics and effects. ( Anderson, P; Bondesson, U; Odar-Cederlöf, I, 1990) |
| " In their retrospective study they studied the acute antihypertensive effect of nifedipine in patients with essential hypertension who were smokers and nonsmokers." | 3.68 | [Blood pressure lowering effect of nifedipine in smokers and non-smokers]. ( Farsang, C; Kiss, I, 1990) |
| "The effect of lowering the maternal blood pressure with sublingual nifedipine on the fetal heart rate was studied in 51 patients with severe pregnancy-induced hypertension." | 3.68 | Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension. ( Fenakel, K; Friedman, A; Lurie, S, 1990) |
| "Nitrendipine, a calcium entry blocker, was administered by gavage (3 mg/100 g body weight/day) to rats with prolonged angiotensin-II-(AII) induced hypertension." | 3.67 | Nitrendipine reverses vasoconstriction and renal hemodynamic changes in experimental hypertension. ( Huelsemann, JL; McKenzie, DE; Sterzel, RB; Wilcox, CS, 1984) |
| "Ten male patients with essential hypertension were studied on a constant diet (100 mEq of sodium daily) while on placebo, immediately following a 20-mg oral dose of nitrendipine, and during 1 week of nitrendipine therapy (10 mg twice daily)." | 3.67 | Renal effects of nitrendipine monotherapy in essential hypertension. ( Barrett, JD; Eggena, P; Golub, MS; Sambhi, MP; Thananopavarn, C, 1984) |
| "The hemodynamic effects of nitrendipine have been studied at rest and during exercise in eight patients with mild to moderate essential hypertension." | 3.67 | Acute and long-term effects of nitrendipine on resting and exercise hemodynamics in essential hypertension. ( Detry, JM; Lavenne, F; Melin, JA; Nannan, ME; Vanbutsele, RJ, 1984) |
| "The efficacy and safety of nitrendipine in oral doses of 5-40 mg twice daily, alone or in combination with hydrochlorothiazide (50-150 mg/day) and/or propranolol (40-120 mg/day), were evaluated in an open study of 50 patients with severe hypertension with supine diastolic blood pressure (BP) greater than 115 mm Hg." | 3.67 | Efficacy and safety of nitrendipine in patients with severe hypertension: a multiclinic study. ( Jain, AK; Maronde, R; McMahon, FG; Mroczek, W; Ryan, JR; Vlachakis, N, 1984) |
| "The antihypertensive efficacy of the calcium entry blocker nitrendipine administered as monotherapy (20-80 mg; mean, 36/day) on the average for 144 days to 46 patients with essential hypertension (WHO I and II) was investigated in relation to age, pretreatment blood pressure, and plasma renin activity." | 3.67 | Antihypertensive therapy with the long-acting calcium antagonist nitrendipine. ( Block, LH; Bolli, P; Bühler, FR; Erne, P; Kiowski, W; Müller, FB, 1984) |
| "Thirty-seven white patients of both sexes were studied to determine the efficacy and tolerance of nitrendipine for long ambulatory treatment in patients suffering from mild to moderate essential arterial hypertension whose response to the drug had been effective in a previous study." | 3.67 | Long-term effectiveness of BAY e 5009-nitrendipine in the treatment of mild and moderate arterial hypertension. ( Baglivo, HP; Castro, JM; Esper, RC; Esper, RJ; Menna, J; Rohwedder, RW, 1984) |
| " (160 mg, n = 9) on the pressor effect of the unselective alpha-adrenergic agonist noradrenaline, as well as on 3H-yohimbine binding to platelet alpha 2-adrenoceptors was studied in patients with essential hypertension." | 3.67 | Effect of nifedipine and verapamil on alpha-receptor-activation in patients with essential hypertension. ( Distler, A; Fritschka, E; Kribben, A; Lenz, T; Philipp, T; Schudrowitsch, L, 1984) |
| "The effect of long-term treatment with nitrendipine on systemic pressor responses to norepinephrine (NE) and angiotensin II (AII) was evaluated in 11 subjects with mild, uncomplicated hypertension." | 3.67 | Altered pressor responses in long-term nitrendipine treatment. ( Simon, G; Snyder, DK, 1984) |
| "Fourteen patients with vascular disease were studied to evaluate the efficacy of nicardipine hydrochloride as a hypotensive agent in the treatment of acute hypertension occurring during anaesthesia." | 3.67 | Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients. ( Furuya, H; Kishi, Y; Okumura, F, 1984) |
| "Nicardipine, a new calcium antagonist, was given to an insulin-treated diabetic patient with severe hypertension that had resisted ordinary antihypertensive treatment." | 3.67 | Effect of nicardipine in a hypertensive patient with diabetes mellitus. ( Miura, K; Sakata, S, 1984) |
| "We observed marked gingival hyperplasia, similar clinically and histologically to the hyperplasia caused by 5:5 sodium diphenylhydantoin (Dilantin) during the last 18 months in five patients treated by nifedipine." | 3.67 | Gingival hyperplasia caused by nifedipine--a preliminary report. ( Behar, S; Engelberg, IS; Kishon, Y; Ramon, Y, 1984) |
| "Intra-arterial pressure, baroreflex sensitivity and the baroreflex set point were measured in eight patients with essential hypertension during a control period and then after acute treatment (2 h after a 30 mg oral dose) and after chronic treatment (at least 2 months) with nicardipine hydrochloride, a calcium channel antagonist." | 3.67 | Baroreflex setting and sensitivity after acute and chronic nicardipine therapy. ( Littler, WA; Watson, RD; Young, MA, 1984) |
| "The use of nifedipine in patients with hypertension, heart failure, and acute myocardial infarction is discussed." | 3.67 | Nifedipine in hypertension and heart failure. ( Matsui, S; Murakami, E; Murakami, H; Takekoshi, N, 1984) |
| "The calcium antagonist, nifedipine, was given orally to 21 women with acute episodes of severe hypertension during pregnancy or in the puerperium." | 3.67 | Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine. ( Redman, CW; Walters, BN, 1984) |
| "Weekly subcutaneous implantation of 25-mg nitrendipine pellets prevented onset of both spontaneous and deoxycorticosterone-salt hypertension in rats." | 3.67 | Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets. ( Hall, CE; Hungerford, S, 1984) |
| "The antihypertensive effects of nitrendipine were evaluated in 12 subjects with hypertension, one of whom could not tolerate the drug for more than 3 days; hence hemodynamics were studied in the 11 subjects who were treated for 2 wk." | 3.67 | Clinical and systemic hemodynamic effects of nitrendipine. ( Abi-Samra, F; Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1984) |
| "Thirteen patients with essential hypertension were started on pindolol 10-20 mg daily and twelve on nifedipine 20-60 mg daily." | 3.67 | Effect of pindolol and nifedipine alone and in combination on haemodynamic parameters/variables in essential hypertension. ( Otsuka, K; Tsukiyama, H; Yamamoto, Y, 1984) |
| "Both the acute blood pressure lowering and renal effects of the calcium antagonist nicardipine and those after 1 week's treatment were investigated in 10 normotensive volunteers and in 10 patients with mild to moderate essential hypertension." | 3.67 | Antihypertensive and renal effects of nicardipine. ( Geyskes, GG; van Nistelrooy, AE; van Schaik, BA, 1984) |
| "The responses to a supine rest, norepinephrine (NE) and angiotensin II (Ang II) were investigated in the absence and presence of calcium antagonist nifedipine or diltiazem in essential (genetic, arterial) hypertension and normotension in humans." | 3.67 | Increased cardiovascular responses to norepinephrine and calcium antagonists in essential hypertension compared with normotension in humans. ( Aoki, K; Kawaguchi, Y; Sato, K, 1985) |
| " The combination of nitrendipine plus enalapril was also examined in ischemic failure and in rats with spontaneous hypertension." | 3.67 | Enalapril in experimental hypertension and acute heart failure: comparison with calcium channel blockers. ( Adkins, E; Emmert, S; Ludden, CT; Ribeiro, LG; Seymour, AA; Sweet, CS, 1986) |
| "In six patients with essential hypertension, pharmacokinetics and pharmacodynamics of nifedipine were investigated during 6 weeks of treatment." | 3.67 | Pharmacokinetics and hemodynamic effects of long-term nifedipine treatment in hypertensive patients. ( Breimer, DD; Faber, H; Kleinbloesem, CH; van Brummelen, P, 1987) |
| " For this purpose, in a group of 11 patients with essential hypertension we have compared the blood pressure lowering effects of a single oral dose of nifedipine before (100 mmol Na+/day and 40 mmol K+/day) and after sodium depletion (20 mmol Na+/day and 40 mmol K+/day: each period was of 6-8 day duration)." | 3.67 | Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients. ( Bolla, G; Cuspidi, C; Gradnik, R; Leonetti, G; Rupoli, L; Sangiorgio, P; Zanchetti, A, 1987) |
| "To elucidate the renal effects and especially the natriuretic properties of calcium entry blockers, we studied the effect of sublingual nifedipine 20 mg in 16 patients with mild to moderate essential hypertension." | 3.67 | Acute natriuresis induced by inhibition of proximal tubular reabsorption of sodium and water in hypertensives following acute calcium entry blockade with nifedipine. ( Christensen, CK; Jespersen, LT; Krusell, LR; Pedersen, OL; Thomsen, K, 1987) |
| "In comparison with a nonspecific vasodilator, sodium nitroprusside (SNP), we intended to deduce the characteristics of nifedipine (NIF) and captopril (CAP) in the treatment of hypertension." | 3.67 | The effects of nifedipine and captopril on renal function in patients with essential hypertension: comparison with sodium nitroprusside. ( Hara, A; Kawai, C; Matsunaga, M; Nakamura, T; Ogawa, K; Pak, CH, 1987) |
| "The acute and chronic hemodynamic effects of nisoldipine were studied in 19 patients (17 men, 2 women; mean age 43 years) with essential hypertension at rest supine and sitting and during steady state 100 W bicycle exercise." | 3.67 | Central hemodynamic effects at rest and during exercise of acute and chronic treatment with nisoldipine in essential hypertension. ( Haugland, H; Lund-Johansen, P; Omvik, P, 1987) |
| "In six patients with essential hypertension, the pharmacokinetics of nisoldipine were investigated before, during, and after 4 weeks of treatment." | 3.67 | Pharmacokinetics and hemodynamic effects of long-term nisoldipine treatment in hypertensive patients. ( Breimer, DD; Danhof, M; Quekel, RP; van Brummelen, P; van Harten, J, 1989) |
| "Acute effects of coronary vasodilators (nifedipine, nicardipine, and nitroglycerin) on atrial natriuretic peptide (ANP) and the renin-angiotensin-aldosterone system were studied in normal subjects and patients with essential hypertension." | 3.67 | Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension. ( Aizawa, T; Ishihara, M; Iwasaki, T; Niwa, A; Shinoda, T; Yamada, T, 1989) |
| "Fourteen patients with previously untreated essential hypertension and left ventricular hypertrophy were treated with a fixed-dose combination of acebutolol 200 mg and nifedipine 20 mg once daily for a followup of 25." | 3.67 | Regression of left ventricular hypertrophy by acebutolol and nifedipine. ( Behr, U; Franz, IW; Ketelhut, R; Tönnesmann, U, 1989) |
| "Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean arterial pressure 132 +/- 4 4 mm Hg) by the combination of a converting enzyme inhibitor and a diuretic." | 3.67 | Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic. ( Mimran, A; Ribstein, J, 1985) |
| "In the present study, we report a case of pheochromocytoma whose high blood pressure was well controlled by single-agent therapy with long-acting nifedipine, in spite of the failure of the combination of labetalol and prazosin in lowering blood pressure satisfactorily." | 3.67 | Effectiveness of long-acting nifedipine in pheochromocytoma. ( Fujiwara, R; Kutsumi, Y; Miyabo, S; Nakai, T; Takahashi, S; Tamai, T, 1989) |
| "As many as 52 patients with essential hypertension aggravated by circulatory failure were examined for the clinical, hemodynamic and neurohumoral parameters during furosemide stimulation." | 3.67 | [The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension]. ( Orynchak, MA, 1989) |
| "The aim of the study was to investigate the effect of nifedipine on blood flow and resistance in the forearm vascular bed of skeletal muscle in 10 male patients with primary hypertension and 10 age-matched male normotensives." | 3.67 | Vasodilation in the vascular bed of skeletal muscle after intravenous nifedipine in normotensives and hypertensives. ( Anlauf, M; Weber, F, 1989) |
| " In this study, nifedipine was administered in doses of 40 to 80 mg/day to 14 patients with essential hypertension, and its hemodynamic effects were evaluated by non-invasive methods, and its effect on glucose metabolism by an arginine infusion test." | 3.67 | Hemodynamic and endocrine effects of acute and chronic administration of nifedipine. ( Chiasson, JL; Larochelle, P; Parent, R, 1989) |
| " This hypertension was managed with either prazosin (n = 29) or nifedipine (n = 17)." | 3.67 | Cyclosporine-associated hypertension in cardiopulmonary transplantation. The beneficial effect of nifedipine on renal function. ( Bateman, DN; Dark, JH; Kirk, AJ; Omar, I, 1989) |
| "This study was undertaken to determine the acute effects of nifedipine on left ventricular filling, examined by Doppler echocardiography in patients with arterial hypertension and normal left ventricular systolic function." | 3.67 | [Modification of left ventricular filling after acute administration of nifedipine in hypertensive patients. Doppler echocardiographic study]. ( Baccarini, S; Barilli, A; Bernardini, B; Bigoli, M; Bolognesi, R; Ghirarduzzi, A; Manca, C; Piazza, A, 1989) |
| "Electronic data collection was used in this open study to survey the safety and efficacy of nifedipine when used in the treatment of 3972 patients with mild to moderate essential hypertension." | 3.67 | Safety and efficacy of nifedipine 20 mg tablets in hypertension using electronic data collection in general practice. ( Marley, JE, 1989) |
| "The antihypertensive efficacy and effects on body fluid composition of monotherapy with the calcium antagonist nifedipine were investigated in 15 patients with essential hypertension." | 3.67 | Effect of long-term nifedipine treatment on body fluid composition in essential hypertension. ( Andersen, GS; Toftdahl, DB, 1989) |
| "1 years) with arterial hypertension nifedipine has been administered sublingually in a single dose of 20 mg and the hypotensive effect of that drug under the control of its concentration in the blood serum was evaluated." | 3.67 | [Nifedipine level in the blood and its immediate hypotensive effect after its sublingual administration to aged patients]. ( Czarnecka, D; Dubiel, JP; Grodzicki, T; Gryglewska, B; Kawecka-Jaszcz, K; Kocemba, J; Skoczeń, M; Witek, J, 1989) |
| "Fifty-two cases of hypertension were treated with verapamil." | 3.67 | [Therapeutic effect of verapamil in hypertension: an analysis of 52 cases]. ( Wang, JJ; Wen, ZB; Zong, JL, 1989) |
| "In nine young normotensive subjects with no family history of hypertension and nine age-matched normotensive subjects with one parent with essential hypertension, effective renal plasma flow (p-aminohippuric acid clearance), glomerular filtration rate (inulin clearance), and excretion of sodium and exogenously administered lithium were measured for 90 minutes before and after administration of a single 20-mg oral dose of the calcium entry blocker nifedipine." | 3.67 | Abnormal renal responses to calcium entry blockade in normotensive offspring of hypertensive parents. ( Colla, R; Coruzzi, P; Guerra, A; Montanari, A; Novarini, A; Ragni, G; Vallisa, D, 1988) |
| "The influence of nifedipine treatment on plasma (PV) and extracellular fluid volume (ECV), the ratio of plasma volume to interstitial fluid volume (PV:IF), glomerular filtration rate (GFR), renal clearances of Na+ and K+, plasma concentrations of renin (PRC), angiotensin II (pANG II), aldosterone (pAldo), adrenaline (PA) and noradrenaline (PNA) were studied in 18 consecutive patients with essential hypertension." | 3.67 | The influence of nifedipine treatment on counter-regulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Mølbak, AG; Nielsen, F; Nielsen, MD, 1985) |
| "The hemodynamic effects of the slow release form of a calcium channel blocker, nifedipine retard, in essential hypertension patients after angiotensin II (AII) infusion were studied using nuclear ventriculography." | 3.67 | Hemodynamic effects of nifedipine in hypertension in the presence of elevated angiotensin-II and beta-adrenergic blockade. ( Battler, A; Blau, A; Cohen, D; Eldar, M; Eliahou, HE; Iaina, A; Kapuler, S; Neufeld, HN; Rath, S, 1986) |
| "Nifedipine slow release tablets were substituted for minoxidil in the treatment of 13 patients with hypertension refractory to conventional therapy." | 3.67 | Nifedipine substituted for minoxidil in the treatment of refractory hypertension. ( Bing, RF; Heagerty, AM; Swales, JD; Thurston, H, 1987) |
| "Thirteen patients with hypertension and normal renal function received nitrendipine, a calcium entry blocker." | 3.67 | Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension. ( Bravo, EL; Fouad, FM; Pedrinelli, R; Tarazi, RC; Textor, SC, 1986) |
| " On this basis, functional and therapeutical regimen of regression of cardiac hypertrophy (prazosin, clonidine, nifedipine) are analyzed in concentric as well as in excentric hypertrophy in patients with arterial hypertension." | 3.67 | [Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects]. ( Strauer, BE, 1985) |
| "The effect of long-term treatment with the calcium antagonist nisoldipine on development of hypertension, cardiac hypertrophy, and plasma levels of atrial natriuretic peptides (ANP) was determined in spontaneously hypertensive rats (SHR) and Wistar-Kyoto rats (WKY) of the same age." | 3.67 | Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats. ( Hirth, C; Kazda, S; Morich, F; Stasch, JP, 1987) |
| " We prospectively studied the effects of amlodipine, a once-a-day dihydropyridine calcium channel antagonist, in 19 patients with essential hypertension." | 3.67 | Amlodipine therapy corrects renal abnormalities encountered in the hypertensive state. ( Bauer, JH; Hamory, A; Lau, A; Reams, GP, 1987) |
| "The effects of 2 calcium antagonist drugs, verapamil and nifedipine, on blood pressure, heart rate (HR), plasma catecholamines, plasma renin activity and some echocardiographic indexes of left ventricular anatomy and function were studied in 67 patients with essential hypertension." | 3.67 | Adrenergic activity and left ventricular function during treatment of essential hypertension with calcium antagonists. ( Agabiti-Rosei, E; Beschi, M; Castellano, M; Muiesan, G; Muiesan, ML; Romanelli, G, 1986) |
| "Nifedipine, in a slow release preparation, was given at a mean daily dosage of 47 +/- 4 mg to 12 patients with severe hypertension in whom arterial pressure was not satisfactorily controlled (mean blood pressure, 172 +/- 6/111 +/- 4 mmHg) by the association of a converting enzyme inhibitor and a diuretic." | 3.67 | Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic. ( Mimran, A; Ribstein, J, 1986) |
| "Evidence has been provided on the increased presence, in essential hypertension, of endogenous digitalis-like factor(s) [DLIS, digoxin-like immunoreactive substance(s)] able to cross-react with antidigoxin antibodies and to inhibit the membrane-bound sodium-potassium pump." | 3.67 | Acute hypotensive effect of calcium antagonists and endogenous digitalis-like immunoreactivity in human essential hypertension. ( Balzan, S; Clerico, A; Del Chicca, MG; Fommei, E; Gazzetti, P; Genovesi-Ebert, A; Ghione, S; Giaconi, S; Marabotti, C; Palombo, C, 1986) |
| "The objective of this prospective study was to evaluate the effect of nifedipine administered at usual daily doses of 30 to 40 mg on the carotid flow in arterial hypertension." | 3.67 | [Effects of nifedipine on carotid blood flow and baroreflex response in essential arterial hypertension. Preliminary results]. ( Allal, J; Barraine, R; Baylac-Domengetroy, F; Begon, F; Chaix, AF; Coisne, D; Gallimard, JF; Petitalot, JP, 1986) |
| "Nifedipine was used successfully in nine patients with refractory hypertension and left ventricular hypertrophy who had symptoms of congestive heart failure despite preserved left ventricular systolic function." | 3.67 | Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function. ( Dzau, VJ; Given, BD; Lee, TH; Stone, PH, 1985) |
| "To assess the clinical efficacy of chronic nitrendipine therapy in mild to moderate essential hypertension, we studied blood pressure (BP) and heart rate responses in 22 subjects receiving maintenance nitrendipine therapy." | 3.67 | Effects of chronic nitrendipine on casual (office) and 24-hour ambulatory blood pressure. ( McCabe, EJ; Meeran, MK; Smith, VE; White, WB, 1985) |
| ", a new calcium entry blocker similar in structure to nifedipine, on blood pressure has been evaluated in 14 patients (aged 24-62 years) with uncomplicated mild or moderate arterial hypertension." | 3.67 | Age related antihypertensive effect of nitrendipine, a new calcium entry blocking agent. ( Fasano, ML; Ferrara, LA; Soro, S, 1985) |
| "The effects and safety of using sublingually nifedipine 10-20 mg as acute antihypertensive treatment were evaluated in 108 patients with hypertensive emergencies or urgency without intensive care monitoring." | 3.67 | Treatment of hypertensive emergencies with nifedipine. ( Donas, G; Karachalios, GN; Stathakakis, V; Tsimiklis, S, 1988) |
| "Changes in glomerular filtration rate and effective renal plasma flow following a protein meal were measured in seven patients with essential hypertension on no treatment and after 6 weeks' treatment with nifedipine and mefruside." | 3.67 | Effect of nifedipine and mefruside on renal reserve in hypertensive patients. ( Anderton, JL; Notghi, A, 1988) |
| "Sublingual nifedipine was used for the treatment of acute severe hypertension in 12 children with renal disease." | 3.67 | Sublingual nifedipine in acute severe hypertension. ( Brocklebank, JT; Evans, JH; Shaw, NJ, 1988) |
| "The hypothesis that nifedipine may cause an insidious but reversible change in glucose tolerance, similar to that associated with thiazide therapy, was studied in six nondiabetic and six noninsulin-dependent diabetic patients with hypertension." | 3.67 | Effect of nifedipine on glucose tolerance, serum insulin, and serum fructosamine in diabetic and nondiabetic patients. ( Al-Hussary, N; Atkins, TW; Beevers, DG; Gill, JS; Pasi, KJ; Zezulka, AV, 1987) |
| "The immediate haemodynamic effects of the calcium antagonist nilvadipine have been studied in ten patients with established mild essential hypertension." | 3.67 | Effect of the calcium antagonist nilvadipine on haemodynamics at rest and during cold stimulation in essential hypertension. ( Hashimoto, N; Hattori, N; Nakamura, S; Ohta, H; Satoh, S; Takabatake, T; Yamada, Y; Yamamoto, Y, 1987) |
| "Acute nifedipine tests and courses of nifedipine treatment were conducted in 30 patients with essential hypertension." | 3.67 | [Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients]. ( Liventseva, MM; Nechesova, TA; Pavlova, AI; Sidorenko, GI, 1988) |
| ") was evaluated as a replacement therapy for long-acting nifedipine (40-120 mg/day) in 21 patients with severe hypertension, who were resistant to or intolerant of nifedipine." | 3.67 | Nisoldipine: a replacement therapy for nifedipine in the treatment of severe hypertension. ( Grossman, E; Rosenthal, T, 1988) |
| " Nifedipine has been shown to cause acute and chronic natriuresis and diuresis, which are important in the ability to use nifedipine chronically in essential hypertension." | 3.67 | Acute effects of nifedipine on renal electrolyte excretion in normal and hypertensive subjects. ( Graves, J; Kenamond, TG; Whittier, FC, 1988) |
| "Slow-release nifedipine has been used in the treatment of severe hypertension in 23 pregnant women." | 3.67 | Nifedipine as a second line antihypertensive drug in pregnancy. ( Beevers, DG; Constantine, G; Luesley, DM; Reynolds, AL, 1987) |
| "The effect of nifedipine on plasma lipids given over a period of one month to 14 patients with essential hypertension was studied." | 3.67 | The effect of nifedipine on plasma lipids in patients with essential hypertension. ( Jarvensiven, P; Lehto, H; Lehtonen, A; Tanskanen, A, 1986) |
| "The aim of this study was to investigate the effect of orally administered, slow-release, nifedipine tablets on the circadian rhythm of blood pressure and heart rate, in hospital patients with clinical diagnosis of hypertension validated by a chronobiologic inferential statistic method." | 3.67 | Slow-release nifedipine: effect on the circadian rhythm of blood pressure in essential hypertension. ( degli Uberti, E; Margutti, A; Montanari, L; Pansini, R; Portaluppi, F; Rambaldi, R; Strozzi, C; Trasforini, G, 1987) |
| "To assess the effect of potent vasodilator therapy in patients with severe or resistant hypertension, 10 patients underwent therapy with captopril and nifedipine alone and in combination." | 3.67 | Effects of combination therapy with captopril and nifedipine in severe or resistant hypertension. ( Lane, TJ; Podesla, S; Viadero, JJ; White, WB, 1986) |
| "The influence of long-term nifedipine treatment on body fluid compartments, renal function, the renin-angiotensin system, and the adrenergic system was studied in 18 patients with essential hypertension." | 3.67 | Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension. ( Bruun, NE; Hartling, OJ; Ibsen, H; Moelbak, AG; Nielsen, F; Nielsen, MD, 1986) |
| "The effect of 8 weeks treatment with the calcium antagonist felodipine--a new long-acting dihydropyridine derivative--in a dose of 10 mg twice daily was studied in 10 male patients with essential hypertension, WHO grade I-II, aged 25-62 years." | 3.67 | The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension. ( Hökfelt, B; Hulthén, UL; Katzman, PL, 1986) |
| ") test was used to study the effect of a calcium inhibitor, Nifedipine, on middle cerebral artery smooth muscle and its cerebrovascular effects in 28 subjects: 8 cases of hypertension, 9 of sylvian artery stenosis confirmed by arteriography (5 approximately equal to 30% and 4 greater than or equal to 50%) and 11 healthy volunteers." | 3.67 | [Transcranial Doppler study of sylvian vascular reactivity as affected by a calcium inhibitor. Preliminary results apropos of 28 cases]. ( Bertrand, P; De Bray, JM; Jeanvoine, H; Joseph, PA; Maugin, D, 1987) |
| "Nifedipine has been used in the management of hypertension in 36 consecutive patients who could not tolerate, or were not controlled by, atenolol and thiazide diuretics." | 3.67 | Use of nifedipine as the drug of third choice in management of hypertension. ( Muir, AL; Roulston, JE; Wathen, CG, 1986) |
| "A new vasodilating agent, minoxidil, was used in 17 patients with essential hypertension that had not responded sufficiently to combined treatment with 3 or 4 conventional hypotensive agents." | 3.67 | [The vasodilator minoxidil in the treatment of hypertension]. ( Iurenev, AP; Nekrasova, AA; Panfilov, VV; Patrusheva, IF, 1987) |
| "The results are reported from the administration of nifedipine to 39 patients with arterial hypertension." | 3.67 | [Nifedipine in the treatment of arterial hypertension]. ( Dimitrova, V; Dzhoneva, S; Monova, D; Simeonova, N; Stoianova, M, 1987) |
| "Nifedipine (Adalat) was used in managing acute hypertension in 20 patients with coronary heart disease during endarterectomy for carotid stenosis." | 3.67 | [Treatment of hypertensive crises with nifedipine (Adalat) in patients at risk of infarct during interventions on the extracranial cerebral vessels]. ( Balzer, K; Fanoulas, G; Fidorra, K; Gresser, S; Müller, C, 1987) |
| "To assess the role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems in the diuretic and natriuretic actions of nifedipine, a calcium-channel blocker, 20 mg of nifedipine was administered orally to 15 patients with essential hypertension." | 3.67 | Hypotensive and natriuretic effects of nifedipine in essential hypertension. Role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems. ( Abe, K; Kohzuki, M; Kudo, K; Omata, K; Sato, M; Seino, M; Tanno, M; Tsunoda, K; Yasujima, M; Yoshinaga, K, 1986) |
| "The antihypertensive effects of the calcium antagonist diltiazem, both alone and combined with the diuretic mefruside, were assessed over 14 months in 36 patients with essential hypertension." | 3.67 | Effects of diltiazem alone and combined with mefruside on cardiovascular response at rest and during exercise, carbohydrate metabolism and serum lipoproteins in patients with systemic hypertension. ( Distler, A; Gotzen, R; Meyer-Sabellek, W; Röcker, L; Schulte, KL, 1987) |
| "Moderate dietary sodium restriction with moderate dietary potassium supplementation was used in patients with essential hypertension who were treated with nifedipine retard by mouth every twelve hours." | 3.67 | [The combination of nifedipine and a low sodium diet with potassium supplement in the therapy of essential arterial hypertension]. ( Digiesi, V; Parigi, P, 1987) |
| "A new oral sustained release formulation containing 20 mg nifedipine (Coral retard) was administered twice daily to 30 patients suffering from coronary diseases and/or hypertension, in order to assess its clinical effectiveness." | 3.67 | Clinical efficacy and bioavailability of a sustained release nifedipine formulation. ( Piovella, C, 1987) |
| "The results of treating 235 hypertensive patients who had been prescribed nifedipine in a hypertension clinic were examined for factors affecting blood pressure response and the frequency of side-effects." | 3.67 | An audit of nifedipine in a hypertension clinic. ( Beevers, DG; Beevers, M; Gill, JS; Zezulka, AV, 1986) |
| "In patients with essential hypertension, the pharmacokinetics of nifedipine in 2 forms (capsule, 10 mg nifedipine dissolved in an organic solvent; slow release tablet, 20 mg nifedipine) and their pharmacodynamic effectiveness on arterial pressure were studied." | 3.67 | Pharmacokinetics and pharmacodynamics of conventional and slow release forms of nifedipine in essential hypertensive patients. ( Abe, K; Imai, Y; Nihei, M; Sasaki, S; Sekino, H; Yoshinaga, K, 1986) |
| "Felodipine is a new dihydropyridine calcium antagonist, and in hypertension it is a much more effective "third-line" drug than hydralazine." | 3.67 | Felodipine compared to nifedipine as "third-line drug" in resistant hypertension. ( Maclean, D; Mitchell, ET; Readman, AS, 1986) |
| "The radioactive microsphere technique was used to study hemodynamic mechanisms of action of 2 calcium antagonists--foridon and nifedipine in conscious rabbits with acute hypertension evoked by immobilization." | 3.67 | [Hemodynamic mechanisms of the hypotensive action of the new calcium antagonist foridon in acute hypertension in rabbits. A comparison with nifedipine]. ( Dugin, SF; Glukhovtsev, EV; Medvedev, OS, 1986) |
| "The effects of chronic dietary salt-loading and nifedipine therapy on hypertension-prone (SBH), -resistant (SBN) and parental (SB) Sabra rats were investigated." | 3.67 | Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment. ( Ben-Ishay, D; Ebsen, W; Garthoff, B; Kazda, S; Luckhaus, G, 1985) |
| "The effects of nifedipine (Adalat) on glucose metabolism and insulin release were studied in rats and in patients with type 2 diabetes mellitus complicated with hypertension." | 3.67 | Effects of nifedipine on insulin secretion and glucose metabolism in rats and in hypertensive type 2 (non-insulin dependent) diabetics. ( Kajiyama, S; Kanatsuna, T; Kano, Y; Kitagawa, Y; Kondo, M; Mori, H; Nakamura, N; Nakano, K; Nishioka, H; Yoshida, T, 1985) |
| "Ten mg of nifedipine was administered to 19 patients with severe hypertension (mean blood pressure 187 +/- 17/122 +/- 12 mm Hg) without intensive care monitoring." | 3.67 | Oral nifedipine for the treatment of patients with severe hypertension. ( Bursten, SL; Davidson, RC; Keeley, PA; Kenny, MA; Stewart, DK, 1985) |
| "Cardiovascular, baroreflex and humoral responses were evaluated in 8 patients with essential hypertension during a control period and then after oral treatment for 5 days with nicardipine hydrochloride 60 mg/d, a calcium channel antagonist." | 3.67 | Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy. ( Biggi, A; Coruzzi, P; Musiari, L; Novarini, A; Ravanetti, C, 1985) |
| "Exchangeable sodium, blood volume, plasma norepinephrine (NE), epinephrine, renin and aldosterone levels, and pressor responses to infused NE or angiotensin II (AII) were assessed in ten patients with essential hypertension on placebo, following 6 to 8 weeks of calcium-antagonist nifedipine (NIF), 3 X 10 to 20 mg/day, and after 6 to 8 weeks on NIF combined with the diuretic chlorthalidone (CHLOR), 25 to 50 mg/day." | 3.67 | Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine. ( Beretta-Piccoli, C; Bianchetti, MG; Bomio, F; Luisoli, S; Marone, C; Weidmann, P, 1985) |
| "The cost-effectiveness of nifedipine for the control of acute hypertension is analyzed." | 3.67 | Managing acute hypertension: cost considerations. ( Cameron, JM; Ellrodt, AG; Luce, BR; Riedinger, M, 1985) |
| "The central and peripheral haemodynamic effects of the administration of 10 mg nifedipine sublingually in 6 patients with essential hypertension were compared with those observed after the administration of one 20 mg slow release tablet of nifedipine in 7 other hypertensive patients of the same age." | 3.67 | [Central and peripheral hemodynamic effects of nifedipine administered orally and sublingually in essential arterial hypertension]. ( Bouthier, JD; Levenson, J; Maarek, BC; Safar, ME; Simon, AC, 1985) |
| "Nine patients with untreated essential hypertension (random blood pressure 173/109 +/- 14/7 mmHg) were studied before and after 16 weeks' treatment with oral nifedipine 10 mg three times a day." | 3.67 | [Effect of nifedipine on arterial pressure and control of the cardiac reflex]. ( Littler, WA; McLeay, RA; Stallard, J; Watson, RD, 1985) |
| "This study was designed to evaluate the efficacy of oral nicardipine in 91 patients with uncomplicated essential hypertension over a period of 12 months." | 3.67 | A study of the long-term efficacy and tolerability of oral nicardipine in hypertensive patients. ( Frais, MA; Jackson, N; Lee, P; Reynolds, G; Silke, B; Taylor, SH; Verma, SP, 1985) |
| "The importance of counterregulatory mechanisms triggered by arterial vasodilation for the antihypertensive response to the calcium entry blocking agent nifedipine was investigated in 13 men with mild to moderate essential hypertension." | 3.67 | Acute and chronic sympathetic reflex activation and antihypertensive response to nifedipine. ( Bertel, O; Bolli, P; Bühler, F; Erne, P; Kiowski, W, 1986) |
| "The antihypertensive effect of finoptin (verapamil) and corinfar (nifedipin) and their impact on the hemodynamics and the repolarization complex of the ECG were studied in 52 patients with essential hypertension and 48 patients with secondary arterial hypertension." | 3.67 | [Treatment of arterial hypertension with calcium antagonists]. ( Grigorian, TZ; Gurgenian, SV; Mikaelian, ES; Nikogosian, KG; Tatinian, NG, 1985) |
| "The antihypertensive and vasodilator effects of felodipine, a new calcium antagonist of the dihydropyridine group, were examined in 15 patients with moderate to severe hypertension." | 3.67 | Effect of felodipine and metoprolol on muscle and skin arteries in hypertensive patients. ( Clement, DL; De Pue, NY, 1985) |
| "The new calcium antagonist felodipine with a pronounced arteriolar dilating capacity was used to treat 11 patients with severe hypertension resistant to treatment (4 with essential hypertension, 5 with renoparechymatous hypertension, 2 with renovascular hypertension)." | 3.67 | Renal effects of felodipine in hypertensive patients with reduced renal function. ( Aurell, M; Björck, S; Granérus, G; Herlitz, H, 1985) |
| "To determine the efficacy of nifedipine combined with propranolol in the treatment of hypertension, 23 patients with essential hypertension uncontrolled while they were receiving propranolol, 120 mg/d, entered a dose response trial of four 8-week periods while continuing propranolol therapy." | 3.67 | Effect of nifedipine and propranolol on blood flow, venous compliance and blood pressure in essential hypertension. ( Ogilvie, RI, 1985) |
| "Labile high blood pressure and associated complaints (eg, severe headache, palpitation, and vague discomfort in the chest) in a 28-year-old woman with pheochromocytoma were stabilized by adding nifedipine to the conventional regimen of alpha- and beta-blocking agents." | 3.67 | Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine. ( Chimori, K; Miura, K; Miyazaki, S; Nakajima, T, 1985) |
| "The efficacy of Nifedipine (N) as an antihypertensive drug was assessed in 4 children aged 6-12 years with acute severe hypertension." | 3.67 | [Experiences with nifedipine in the treatment of acute hypertension in childhood]. ( Jüngst, BK; Schranz, D; Stopfkuchen, H; Ziegler, R, 1985) |
| "Twelve patients with uncomplicated systemic hypertension were treated with nifedipine (30 mg/day) and diltiazem (180 mg/day) for 1 month each, and performed two stage (50 watt and 100 watt) of bicycle ergometer exercise before and after each period of administration." | 3.67 | Effects of nifedipine and diltiazem on hemodynamic responses at rest and during exercise in hypertensive patients. ( Nakano, T; Oonishi, N; Takezawa, H; Yamakado, T, 1985) |
| "Long-acting nifedipine tablets were given to 47 severely and moderately hypertensive patients with renal insufficiency, cardiovascular, cerebrovascular, and peripheral vascular disease, diabetes mellitus, asthma, and systemic lupus erythematosus." | 3.67 | Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases. ( Bursztyn, M; Grossman, E; Rosenthal, T, 1985) |
| "Eight untreated patients with essential hypertension (average casual blood pressure 180/110 +/- 27/12 mm Hg) were studied following control, acute (a single oral dose of 30 mg nicardipine hydrochloride), and chronic (2 months nicardipine oral therapy) treatment periods." | 3.67 | The effect of nicardipine on blood pressure, its variability and reflex cardiac control. ( Littler, WA; Young, MA, 1985) |
| "In 16 people with essential hypertension, heart rate (HR), blood pressure (BP) and relative cardiac volumes were measured at rest and during submaximal upright exercise before and after 10 mg of sublingual nifedipine using radionuclide ventriculography." | 3.67 | Afterload reduction by nifedipine--the acute haemodynamic response to exercise in hypertensive subjects. ( Hannan, WJ; Muir, AL; Turnbull, LW; Wathen, CG, 1985) |
| "We present a case of a 79-year-old woman with periods of syncope, complete heart block (CHB), and ventricular standstill during periods of increased vagal tone following sublingual nifedipine for hypertension." | 3.67 | Syncope and conduction disturbances following sublingual nifedipine for hypertension. ( Wolford, R; Zangerle, KF, 1985) |
| "The effect of nifedipine on cellular electrolytes was studied in 14 patients (10 males, 4 females, age 39-62 years) with untreated primary hypertension." | 3.67 | Effect of nifedipine on cellular electrolytes in fourteen patients with untreated primary hypertension. ( Ericsson, F, 1985) |
| "The effect of nicardipine on experimental hyperlipemia induced by a 1% cholesterol diet in spontaneously hypertensive rats (SHR) was investigated by the change of hemodynamics and the determination of lipid contents of the serum, liver, heart and aorta." | 3.67 | [Effect of nicardipine on cholesterol-fed S.H.R]. ( Kawashima, I; Nakayama, S; Ohba, T; Sakamoto, K; Tonooka, M; Yasuhara, H, 1985) |
| " Two cases and a review of the literature relating to treatment of hypertensive emergencies with nifedipine are presented." | 3.67 | Nifedipine in the management of hypertensive emergencies: report of two cases and review of the literature. ( Checcio, LM; Cohan, JA, 1985) |
| "A study was carried out to evaluate the efficacy and tolerance of oral nifedipine in hypertensive emergencies." | 3.67 | Oral nifedipine in hypertensive emergencies. ( Alexander, T; Dennison, D; Jose, J; Mathai, D; Pulimond, BM, 1985) |
| "The calcium-channel blocker, nifedipine, was used as additional oral therapy to beta-adrenergic receptor blockade by the cardioselective agent, atenolol, in the therapy of 31 patients with hypertension." | 3.66 | Antihypertensive effects of nifedipine combined with cardioselective beta-adrenergic receptor antagonism by atenolol. ( Jee, L; Opie, LH; White, D, 1982) |
| "Captopril was administered (50 mg orally) to 88 untreated hypertensive patients (70 with essential hypertension, eight with renal arterial disease, 10 with renal parenchymal disease) and to 25 hypertensive patients treated with sympatholytic or beta-blocking agent (20 with essential hypertension, five with renal arterial disease)." | 3.66 | Evaluation of the chronotropic property of captopril in hypertensive patients. ( Abe, K; Goto, T; Haruyama, T; Hiwatari, M; Imai, Y; Kasai, Y; Sato, K; Sato, M; Tajima, J; Yoshinaga, K, 1982) |
| "Nifedipine has been assessed as a possible alternative to other third line drugs in the management of patients with difficult to control hypertension." | 3.66 | Nifedipine in the treatment of difficult hypertensives. ( Dean, S; Kendall, MJ, 1983) |
| "In 13 patients with essential and renal hypertension, the influence of nifedipine on the intracellular free Ca2+ concentration was tested." | 3.66 | Effect of nifedipine on blood pressure and on intracellular calcium in arterial hypertension. ( Losse, H; Vetter, H; Zidek, W, 1982) |
| "The acute effects of two calcium channel blockers, nifedipine and verapamil, were compared in eight normotensive subjects and eight patients with essential hypertension." | 3.66 | Comparison of cardiovascular, renal, and humoral effects of acute administration of two calcium channel blockers in normotensive and hypertensive subjects. ( Cuspidi, C; Leonetti, G; Sampieri, L; Terzoli, L; Zanchetti, A, 1982) |
| "Nifedipine was given to 15 patients with essential hypertension for 6 weeks and to 8 normotensive subjects for 5 days." | 3.66 | Contrasting effects of nifedipine, captopril, and propranolol in normotensive and hypertensive subjects. ( MacGregor, GA; Markandu, ND; Rotellar, C; Sagnella, GA; Smith, SJ, 1982) |
| "The efficacy and safety of 20 mg of nifedipine as a single oral dose have been studied with respect to the use of the drug as an alternative treatment of hypertensive emergencies." | 3.66 | An oral calcium antagonist for treatment of hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC, 1982) |
| "Ten milligrams nifedipine was administered orally to young and old persons with or without hypertension, and the acute effects of nifedipine on the renin-angiotensin-aldosterone system were studied one half to 3 hours later." | 3.66 | Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension. ( Hiramatsu, K; Kubota, T; Yamada, T; Yamagishi, F, 1982) |
| "Nine patients with untreated essential hypertension (mean casual blood pressure 173/109 +/- 14/7 mm Hg) (+/- SD) were studied in the control state and after 16 weeks of treatment with nifedipine, 10 mg orally every 8 hours." | 3.66 | The effect of nifedipine on arterial pressure and reflex cardiac control. ( Littler, WA; McLeay, RA; Stallard, TJ; Watson, RD, 1983) |
| "The acute response to nifedipine 5 mg was studied in 11 young normotensive subjects and 18 older normotensive subjects who were age matched with 33 patients with uncomplicated essential hypertension." | 3.66 | The acute response to nifedipine is related to pre-treatment blood pressure. ( MacGregor, GA; Markandu, ND; Rotellar, C; Sagnella, GA; Smith, SJ, 1983) |
| "The effect of daily treatment (sometimes interrupted) with the calcium blocker nisoldipine at two different dose levels, one double the other, on the development of spontaneous hypertension in the rat was evaluated." | 3.66 | Prevention of spontaneous and glucocorticoid hypertension in rats by nisoldipine. ( Hall, CE; Hungerford, S, 1983) |
| "Nifedipine, a calcium antagonist with a predominant vasodilator action, was evaluated for the treatment of hypertension." | 3.66 | Nifedipine in the treatment of hypertension. ( Blake, S; Brennan, F; Cannon, P; Flanagan, M, 1983) |
| "The forearm vascular resistance (FVR) following intra-arterial infusions of the calcium influx inhibitors nicardipine and verapamil and sodium nitroprusside was compared to that following 10 min arterial occlusion in 10 normotensive (NT) individuals aged 45 +/- 12 years, 12 patients with mild essential hypertension (EH) aged 42 +/- 14 years and 11 patients with moderate EH aged 49 +/- 11 years." | 3.66 | Calcium influx mediated vasoconstriction: studies in patients with mild and moderate essential hypertension. ( Bolli, P; Bühler, FR; Hulthén, UL, 1983) |
| "Sublingual nifedipine 20 mg as an emergency treatment for severe hypertension or hypertensive crisis in 30 patients gave an effective and gradual reduction in blood pressure." | 3.66 | Emergency treatment of hypertensive crisis with sublingual nifedipine. ( Brand, G; Effert, S; Erbel, R; Meyer, J, 1983) |
| "The calcium antagonists nicardipin and verapamil were used to demonstrate enhanced calcium influx dependent vasoconstriction in the forearm circulation of patients with essential hypertension (n = 11) as compared to normotensive subjects (n = 10) while non-specific vasodilatory responses were comparable." | 3.66 | [Calcium antagonists: a potent vasodilatory principle and alternative basic antihypertensive therapy]. ( Bolli, P; Bühler, FR; Erne, P, 1983) |
| "We have assessed the potential antihypertensive effect of a new slow channel blocker, nicardipine, in a group of patients with essential hypertension." | 3.66 | The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise. ( Hornung, RS; Jones, RI; Raftery, EB; Sonecha, T, 1983) |
| "The antihypertensive effect of nifedipine (Adalat), a Ca2+-antagonistic drug, was studied in patients with mild or severe hypertension." | 3.66 | Antihypertensive effect of nifedipine and its relationship to severity of hypertension. ( Ashizawa, H; Ijichi, H; Ochi, Y; Shikuma, R; Takahashi, H; Takashina, R; Takeda, K; Yoshimura, M, 1983) |
| "The effects on blood pressure and renal function of a single 20-mg sublingual dose of nifedipine were investigated in 10 patients with mild to moderate arterial hypertension insufficiently treated on beta-blocker monotherapy." | 3.66 | Renal effects of acute calcium blockade with nifedipine in hypertensive patients receiving beta-adrenoceptor-blocking drugs. ( Christensen, CK; Lederballe Pedersen, O; Mikkelsen, E, 1982) |
| "The immediate hemodynamic effects of a new calcium-channel blocking agent nitrendipine were studied in 12 patients with mild established essential hypertension." | 3.66 | Immediate hemodynamic effects of a new calcium-channel blocking agent (nitrendipine) in essential hypertension. ( Dunn, FG; Frohlich, ED; Messerli, FH; Oigman, W; Reisin, E; Ventura, HO, 1983) |
| "The calcium antagonists, diltiazem and nifedipine, are effective in mild-to-moderate chronic essential hypertension." | 3.66 | Role of calcium antagonists in the treatment of essential hypertension. ( Brandt, D; Härringer, M; Klein, W; Vrecko, K, 1983) |
| "Twenty patients with hypertension uncontrolled by existing therapy with two or three antihypertensive agents (a beta-blocker plus a thiazide diuretic in 10 and with the addition of hydralazine or prazosin in the other 10) were studied to assess the effects of additional long-term administration of nifedipine." | 3.66 | Nifedipine in combination therapy for resistant hypertension. ( Beevers, DG; Sloan, PJ, 1983) |
| "The action of nifedipine tablets was examined in 17 patients with essential hypertension focusing particularly on the profile of blood pressure (BP) reduction over 24 hours resulting from both twice-daily and once-daily therapy (dose range 40 to 120 mg daily)." | 3.66 | Nifedipine tablets for systemic hypertension: a study using continuous ambulatory intraarterial recording. ( Gould, BA; Hornung, RS; Jones, RI; Raftery, EB; Sonecha, TN, 1983) |
| "The hypotensive effect of nifedipine was studied in 9 patients with severe hypertension." | 3.66 | Management of severe hypertension with nifedipine in combination with clonidine or propranolol. ( Abe, K; Chiba, S; Haruyama, T; Imai, Y; Irokawa, N; Ito, T; Miura, Y; Otsuka, Y; Saito, K; Sakurai, Y; Sato, M; Yasujima, M; Yoshinaga, K, 1980) |
| "The immediate hypotensive effect of oral nifedipine was assessed in 15 patients with moderate to severe hypertension." | 3.66 | The immediate hypotensive effect of oral nifedipine. ( Chia, BL; Choo, M; Ee, B; Tan, A, 1982) |
| "16 patients suffering from hypertension and angina pectoris (class II according to the NYHA) are treated with 100 mg atenolol once daily for three weeks." | 3.66 | [Effects of therapy with a association of nifedipine and atenolol in patients with systemic arterial hypertension and angina pectoris]. ( Attisano, N; Grenci, G; Martelli, G; Sarica, G; Schirripa, V, 1982) |
| "The acute and long-term hypotensive effects of low doses of nifedipine, and the correlation between the fall in the blood pressure (BP) and the plasma nifedipine concentration, were investigated in patients with essential hypertension." | 3.66 | Acute and long-term hypotensive effects and plasma concentrations of nifedipine in patients with essential hypertension. ( Aoki, K; Kawaguchi, Y; Sato, K; Yamamoto, M, 1982) |
| "The calcium antagonist nifedipine (Adalat) was administered to 60 patients with essential hypertension and investigations were performed on acute and chronic hypotensive effects." | 3.66 | Antihypertensive effects of the calcium antagonistic agent nifedipine. ( Inoue, E; Komatsu, H; Kotsumi, K; Maeda, K; Minamikawa, H; Tanaka, C; Tsukano, Y, 1982) |
| "The effects of sublingual nifedipine, a calcium antagonist vasodilator, were assessed in 43 patients with moderate to severe hypertension in an emergency room setting." | 3.66 | Efficacy of sublingual nifedipine in the acute treatment of systemic hypertension. ( Beer, N; Cohen, A; Frishman, W; Gallegos, I; Klein, N; Sonnenblick, E, 1981) |
| " Nifedipine, a calcium antagonist drug, was given sublingually (10 mg) to seven normal subjects and 19 patients with essential hypertension." | 3.66 | Acute and chronic effects of nifedipine on plasma renin activity and plasma adrenaline and noradrenaline in controls and hypertensive patients. ( Agabiti-Rosei, E; Bentivoglio, M; Boschetti, E; Corea, L; Miele, N; Muiesan, G, 1979) |
| "Ten mg of Nifedipine, a Ca++ antagonist, was administered orally in 2 groups of patients; Group 1: 6 patients in hypertensive emergency and Group II: 12 patients with intractable, severe hypertension." | 3.66 | A study on the effects of nifedipine in hypertensive crises and severe hypertension. ( Hada, Y; Kamata, C; Kuramoto, K; Kuwajima, I; Matsushita, S; Murakami, M; Ueda, K, 1978) |
| "Oral (17 cases) or sublingual (9 cases) administration of nifedipine (10 mg), a new coronary dilator, induced a prompt and large pressure reduction in patients with severe primary hypertension." | 3.65 | Nifedipine, a new antihypertensive with rapid action. ( Fiorentini, C; Guazzi, M; Magrini, F; Moruzzi, P; Olivari, MT; Polese, A, 1977) |
| "The Ca2+ antagonistic coronary vasodilator, Nifedipine, was sublingually administered by a dose of 30 mg to 19 patients with hypertension." | 3.65 | Hypotensive action and increased plasma renin activity by Ca2+ antagonist (Nifedipine) in hypertensive patients. ( Aoki, K; Kato, S; Sato, I; Tazumi, K; Yoshida, T, 1976) |
| "Preeclampsia is associated with maternal and perinatal morbidity." | 3.30 | Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features. ( Cleary, EM; Costantine, MM; Kudrimoti, M; Patton, KG; Racchi, NW; Rood, KM, 2023) |
| " If BP is not at goal during 4 week's visit, dosage of antihypertensive agents will be doubled." | 2.94 | A comparative study for the effects of nifedipine GITS and amlodipine besylate administrated in daytime or at nighttime on recovery of blood pressure rhythm and arterial stiffness in the young and middle-aged subjects with non-dipper hypertension (NARRAS) ( Liu, J, 2020) |
| "Background Hypertension is common among patients with Alzheimer disease." | 2.90 | Blood Pressure Lowering With Nilvadipine in Patients With Mild-to-Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension. ( Claassen, JAHR; de Heus, RAA; Donders, R; Lawlor, BA; Olde Rikkert, MGM; Santoso, AMM, 2019) |
| "Nilvadipine treatment lowered systolic blood pressure (Δ=-11." | 2.90 | Effects of Nilvadipine on Cerebral Blood Flow in Patients With Alzheimer Disease. ( Claassen, JAHR; de Heus, RAA; de Jong, DLK; Donders, R; Günther, M; Lawlor, BA; Olde Rikkert, MGM; Rijpma, A; van Osch, MJP, 2019) |
| "A total of 626 patients with preeclampsia were enrolled, screened, and assigned by random to groups receiving either nifedipine + placebo or nifedipine + celastrol orally." | 2.84 | Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial. ( Liang, Y; Wang, D; Xiao, S; Zhang, M, 2017) |
| " A trend to dose-response relationship was observed in each subgroup." | 2.82 | Nifedipine GITS/Candesartan Combination Therapy Lowers Blood Pressure Across Different Baseline Systolic and Diastolic Blood Pressure Categories: DISTINCT Study Subanalyses. ( Cha, G; Kjeldsen, SE; Mancia, G; Villa, G, 2016) |
| "The improvement in postprandial lipidemia by nifedipine may add to its anti-atherogenic effects in hypertensive patients." | 2.82 | Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia. ( Charach, G; Grosskopf, I; Harats, D; Kamari, Y; Shaish, A, 2016) |
| " There was a low rate of adverse events in all treatment groups." | 2.82 | Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study. ( Choi, DJ; Kim, DS; Kim, DW; Kim, JH; Lee, HY; Lee, SY; Park, CG; Park, JB; Park, SW; Rim, SJ; Shim, WJ; Shin, JH; Youn, HJ, 2016) |
| "Essential hypertension has been extensively reported to cause endothelial dysfunction." | 2.82 | Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus. ( D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM, 2016) |
| " The primary assessment included the incidence of treatment-emergent adverse events (TEAEs)." | 2.82 | Fixed-dose combination of nifedipine gastrointestinal therapeutic system and candesartan cilexetil in patients with moderate-to-severe essential hypertension: an open-label, long-term safety and efficacy study. ( Dzongowski, P; Kjeldsen, SE; Li, N; Radlmaier, A; Wang, L, 2016) |
| " CR nifedipine (80 mg per day) was generally well tolerated, with the most common drug-related treatment-emergent adverse event being tachycardia (6." | 2.80 | Long-term safety and efficacy of high-dose controlled-release nifedipine (80 mg per day) in Japanese patients with essential hypertension. ( Asano, K; Kajikawa, M; Kimoto, M; Matsuda, Y; Shimamoto, K, 2015) |
| "The aim of this study was to evaluate the effects of perindopril or barnidipine alone or combined with simvastatin on metabolic parameters and hepatic steatosis degree." | 2.80 | Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients. ( D'Angelo, A; Derosa, G; Maffioli, P; Mugellini, A; Pesce, RM, 2015) |
| "The current study addresses the 24-h antihypertensive efficacy and safety of arotinolol combined with a different calcium channel blocker." | 2.79 | The efficacy and safety of arotinolol combined with a different calcium channel blocker in the treatment of Chinese patients with essential hypertension: a one-year follow-up study. ( Chen, W; Fang, H; Liu, X; Xu, W, 2014) |
| "Hypertension is associated with endothelial dysfunction and activated Rho-associated kinases (ROCKs)." | 2.77 | Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension. ( Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Iwamoto, Y; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J, 2012) |
| "Proteinuria is associated with adverse cardiovascular and renal outcomes that are not prevented by current treatments." | 2.76 | Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease. ( Dhaun, N; Goddard, J; Haughie, S; Johnston, NR; Kerr, D; MacIntyre, IM; Melville, V; Webb, DJ, 2011) |
| "The nifedipine group was administered slow-release nifedipine (20 mg) once daily." | 2.73 | Nifedipine improves endothelial function: role of endothelial progenitor cells. ( Dohi, Y; Kimura, G; Kondo, T; Kureishi-Bando, Y; Murohara, T; Numaguchi, Y; Rabelink, TJ; Sugiura, T; Ueda, R; Yoshida, O, 2008) |
| "Previous chronotherapy studies have shown that the circadian pattern of blood pressure (BP) remains unchanged after either morning or evening dosing of several calcium channel blockers (CCB), including amlodipine, isradipine, verapamil, nitrendipine, and cilnidipine." | 2.73 | Dose- and administration time-dependent effects of nifedipine gits on ambulatory blood pressure in hypertensive subjects. ( Ayala, DE; Calvo, C; Chayán, L; Fernández, JR; Fontao, MJ; Hermida, RC; López, JE; Mojón, A; Rodríguez, M, 2007) |
| "Nifedipine is a short-acting calcium antagonist formulated into several different oral preparations, each of which may have different effects on haemodynamics and autonomic nervous function." | 2.71 | Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension. ( Andoh, N; Horinaka, S; Ishimitsu, T; Kobayashi, N; Matsuoka, H; Minami, J; Numabe, A, 2004) |
| "Because hypertension is associated with potentially reversible structural and functional alterations in the cerebral circulation that may improve with treatment, we investigated whether long-term pharmacological reduction of systolic blood pressure will improve, rather than worsen, cerebral blood flow and its regulation." | 2.71 | Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects. ( Babikian, V; Cheng, DM; Cupples, LA; Gagnon, M; Iloputaife, I; Kiely, DK; Lipsitz, LA; Serrador, J; Sorond, F; Vyas, M, 2005) |
| "Nifedipine was effective in 4 of 18 patients, carvedilol, in 4 of 12 patients (22." | 2.71 | Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trial. ( Angeli, P; Boccagni, P; Burra, P; Carraro, A; Cillo, U; Fagiuoli, S; Fasolato, S; Galioto, A; Gatta, A; Guarda, S; Sartori, M; Semplicini, A; Sticca, A; Zanus, G, 2005) |
| "Enalapril was started at 10 mg/day, felodipine-ER at 5 mg/day and nifedipine-GITS at 30 mg/day, all once daily." | 2.70 | Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril. ( Joyner, CD; Leenen, FH; Myers, MG; Toal, CB, 2002) |
| "Nifedipine was absorbed rapidly by not only intestinal mucosa but also the nasal or oral mucosa." | 2.70 | Evaluation of the method for nifedipine administration for a rapid onset of clinical effect: a clinical study in normal volunteers. ( Komiyama, T; Kubota, R; Shimada, H, 2001) |
| "More enalapril-treated than nifedipine-treated patients required supplemental treatment with hydrochlorothiazide (59% versus 34%, P<0." | 2.70 | Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat ( Bella, JN; Dahlöf, B; De Quattro, V; de Simone, G; Devereux, RB; Hahn, RT; Palmieri, V; Sharpe, N; Walker, JF, 2001) |
| "Therapy with OSMO-Adalat of patients with AH combination with KPA provides a good hypotensive effect and relieves symptoms of encephalopathy, myocardial ischemia and orthostatic insufficiency in low risk of side effects." | 2.70 | [Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries]. ( Khirmanov, VN; Sorokoumov, VA; Tiurina, TV; Zakharova, IV, 2001) |
| "Fenoldopam seems to be an efficient alternative to nifedipine, especially because of its more rapid onset of action." | 2.69 | DA1-receptor stimulation by fenoldopam in the treatment of postcardiac surgical hypertension. ( Berger, J; Gombotz, H; Mahla, E; Metzler, H; Plaza, J, 1998) |
| "nilvadipine or terazosin was administered for 2 weeks in a randomized crossover manner." | 2.69 | Comparative efficacies of a calcium antagonist and an alpha1 blocker in elderly hypertensive patients with stroke. ( Abe, I; Fujishima, M; Hasuo, Y; Nishino, Y; Onaka, U; Setoguchi, M, 1998) |
| "Hypertension is a prevalent disease among African Americans, and successful treatment rates are low." | 2.69 | Comparison of the efficacy of dihydropyridine calcium channel blockers in African American patients with hypertension. ISHIB Investigators Group. International Society on Hypertension in Blacks. ( Flack, JM; Hall, WD; Preisser, J; Reed, JW; Yunis, C, 1998) |
| "Nitroglycerin was removed at 6 a." | 2.69 | Contrasting effects of vasodilators on blood pressure and sodium balance in the hypertension of autonomic failure. ( Biaggioni, I; Jordan, J; Paranjape, SY; Pohar, B; Robertson, D; Robertson, RM; Shannon, JR, 1999) |
| " Each time, 24-h blood pressure registration was performed, followed by a clearance study to obtain a 3-h dose-response curve for intravenously infused NG-monomethyl-L-arginine (L-NMMA, respectively 0." | 2.69 | Divergent effects of ACE-inhibition and calcium channel blockade on NO-activity in systemic and renal circulation in essential hypertension. ( Beutler, JJ; Dijkhorst-Oei, LT; Koomans, HA; Rabelink, TJ; Stroes, ES, 1998) |
| "Both nifedipine treatments did neither greatly modify the circadian blood pressure pattern nor reflexly increase heart rate." | 2.69 | Ambulatory blood pressure profiles in essential hypertensives after treatment with a new once daily nifedipine formulation. ( Herholz, C; Hopf, R; Lemmer, B; Nold, G; Sturm, M, 1999) |
| "Isosorbide dinitrate aerosol (ISA) is a nitric oxide fast-acting donor." | 2.69 | Comparison between isosorbide dinitrate aerosol and nifedipine in the treatment of hypertensive emergencies. ( Lozano-Nuevo, JJ; Narvaez-Rivera, JL; Rodriguez-Lopez, L; Rubio-Guerra, AF; Vargas-Ayala, G, 1999) |
| "1." | 2.69 | Control of vascular tone in isolated mesenteric arterial segments from hypertensive patients. ( Hutri-Kähönen, N; Kähönen, M; Nordback, I; Pörsti, I; Sand, J; Taurio, J; Wu, X, 1999) |
| "Nifedipine GITS was well tolerated." | 2.69 | [24-hour blood pressure monitoring in diagnosis and therapy of arterial hypertension]. ( Bachmann, LM; Holm, D; Vetter, W, 1999) |
| "As melatonin has been found to play a role in the mechanisms of cardiovascular regulation, we designed the present study to evaluate whether the evening ingestion of the pineal hormone might interfere with the antihypertensive therapy in hypertensive patients well-controlled by nifedipine monotherapy." | 2.69 | Cardiovascular effects of melatonin in hypertensive patients well controlled by nifedipine: a 24-hour study. ( Fogari, R; Lusardi, P; Piazza, E, 2000) |
| "Amlodipine has potential advantages in children since it can be dissolved into a liquid preparation and has a long elimination half-life, allowing for once-daily administration." | 2.69 | A randomized prospective crossover trial of amlodipine in pediatric hypertension. ( Arbus, GS; Blowey, D; Khattak, S; Koren, G; Lyszkiewicz, DA; Rogan, JW, 2000) |
| " A low incidence of adverse events possibly or probably related to barnidipine (10 or 20 mg/day) monotherapy was reported in the first and second years with headache, peripheral oedema and palpitations the most commonly reported." | 2.69 | The long-term efficacy and safety profile of barnidipine. ( Smilde, JG, 2000) |
| "Treatment with prazosin GITS did not produce any statistically or clinically significant change in the metabolic parameters at the end of 24 weeks, while with nifedipine SR there was a significant increase in the serum LDL values at 24 weeks (p = 0." | 2.69 | Prazosin GITS vs sustained release nifedipine in patients with hypertension and abnormal lipid profile: a randomized, controlled, multicenter study. Madras Hypertension Study Group. ( Joglekar, SJ; Misra, KP; Mukherjee, S; Nanivadekar, AS, 1998) |
| " At the end of the dosing interval, felodipine lowered office DBP (mm Hg) by -18 +/- 12/14 +/- 1 compared to -14 +/- 2/11 +/- 1 for nifedipine (P < or = ." | 2.68 | Differential effects of felodipine and nifedipine on 24-h blood pressure and left ventricular mass. ( Leenen, FH; Myers, MG; Tanner, J, 1995) |
| "Moexipril is a new nonpeptide angiotensin-converting enzyme (ACE) inhibitor with an intermediate duration of action." | 2.68 | Antihypertensive effects of moexipril, a new ACE inhibitor, as add-on therapy to nifedipine in patients with essential hypertension. ( Fox, A; Persson, B; Stimpel, M; Widgren, BR, 1995) |
| "Amlodipine was better tolerated than nifedipine slow release." | 2.68 | Patient compliance and therapeutic coverage: comparison of amlodipine and slow release nifedipine in the treatment of hypertension. The Belgian Collaborative Study Group. ( Block, P; De Backer, G; Degaute, JP; Detry, JM, 1995) |
| "Nifedipine is a dihydropyridine calcium antagonist, and lisinopril is an angiotensin-converting enzyme inhibitor." | 2.68 | Lisinopril improves aortic compliance and renal flow. Comparison with nifedipine. ( Shimamoto, H; Shimamoto, Y, 1995) |
| "Chronic left ventricular hypertrophy (LVH) is associated with depressed contractile performance, abnormal compliance of the chamber, and ultimately, the development of a left ventricular failure." | 2.68 | [The effect of hypotensive drugs on left ventricular mass and diastolic function]. ( Haczyński, J; Jołda-Mydłowska, B; Spring, A; Witkowska, M, 1995) |
| "Atenolol treatment significantly increased triglyceride levels and decreased the HDL-cholesterol levels after 9 months in both groups." | 2.68 | Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects. ( Goyal, RK; Satia, MC; Shukla, ML, 1995) |
| " To assess the effect of orlistat on the bioavailability of nifedipine GITS, a third party-blind, placebo-controlled, randomized, two-way crossover study was performed in 18 healthy volunteers." | 2.68 | Lack of effect of orlistat on the bioavailability of a single dose of nifedipine extended-release tablets (Procardia XL) in healthy volunteers. ( Melia, AT; Mulligan, TE; Zhi, J, 1996) |
| "In nifedipine-treated non-pregnant controls, only EC80 for adrenaline-induced aggregation decreased." | 2.68 | Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy. ( Manninen, A, 1996) |
| "Orlistat was given in doses of 50 mg 3 times daily mid-meal for 7 (nifedipine and captopril) or 8 days (atenolol and furosemide)." | 2.68 | Effect of the lipase inhibitor orlistat on the pharmacokinetics of four different antihypertensive drugs in healthy volunteers. ( Jonkmann, JH; Schmidtke-Schrezenmeier, G; Tam, YK; van Brummelen, P; Weber, C, 1996) |
| "Nifedipine did not produce any effect on LV regional wall motion in group 1, but it induced significant changes in LV regional wall motion in seven patients in group 2." | 2.68 | Relation between exercise-induced left ventricular wall motion abnormalities and coronary artery disease in hypertensive patients: effects of blood pressure normalization. ( Berti, M; Maltagliati, A; Muratori, M; Passaretti, B; Pepi, M; Tamborini, G; Tavasci, E, 1997) |
| "There was a statistically significant difference between daily dosage requirements of tacrolimus at 90 (p = 0." | 2.68 | Nifedipine interaction with tacrolimus in liver transplant recipients. ( Gordon, FD; Jenkins, RL; Lewis, WD; Marcos-Alvarez, A; Seifeldin, RA, 1997) |
| "Hypertensive NIDDM subjects were treated for 3 months with captopril, nifedipine, or doxazosin." | 2.68 | Na+/Li+ and Na+/H+ countertransport activity in hypertensive non-insulin-dependent diabetic patients: role of insulin resistance and antihypertensive treatment. ( Canessa, ML; Castellino, P; DeFronzo, RA; Giordano, M; Solini, A, 1997) |
| "Nifedipine gastrointestinal therapeutic system (GITS) is a once-a-day formulation of nifedipine providing stable plasma concentrations over the entire 24 h dosing interval." | 2.68 | Efficacy of a low dose nifedipine GITS (20 mg) in patients with mild to moderate hypertension. ( Toal, CB, 1997) |
| "Calcium channel blockers facilitate the renal excretion of sodium and this effect is maintained during chronic administration of these drugs." | 2.68 | The natriuretic effect of nifedipine gastrointestinal therapeutic system remains despite the presence of mild-to-moderate renal failure. ( Barrios, V; Campo, C; Esteban, E; Garcia-Vallejo, O; Lahera, V; Manero, M; Rodicio, JL; Ruilope, LM, 1997) |
| " Compared with placebo, barnidipine lowered blood pressure, with a trend toward a dose-response relationship over the dose range 10-30 mg." | 2.68 | Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group. ( Hart, W; Holwerda, NJ, 1997) |
| " Adverse events, possibly related to drug, were more common with nifedipine SR (34%) than with trandolapril (17%; p < 0." | 2.67 | Comparison of the efficacy and safety of trandolapril and nifedipine SR in mild-to-moderate hypertension. Investigator Study Group. ( Pauly, NC; Steiner, G, 1994) |
| "25 hypertensive patients with normal or impaired renal function underwent pharmacokinetic and safety studies after single and multiple dose administration of nifedipine GITS (Gastro-Intestinal Therapeutic System) 60mg tablets." | 2.67 | Pharmacokinetic profile of nifedipine GITS in hypertensive patients with chronic renal impairment. ( Brendel, E; Griffel, L; Iaina, A; Kobelt, R; Schneider, R; Stolero, D, 1994) |
| " The type and incidence of adverse events seen with both drugs are characteristic of the dihydropyridine class of drugs and were mainly due to pharmacologically induced vasodilation, but lacidipine caused a significantly lower incidence of ankle edema than nifedipine SR." | 2.67 | A long-term study comparing lacidipine and nifedipine SR in hypertensive patients: safety data. ( Leonetti, G; Salvi, S, 1994) |
| " However, lacidipine exhibited a lower incidence of adverse events (particularly ankle edema and tachycardia) than nifedipine SR." | 2.67 | Calcium antagonist antihypertensive treatment of non-insulin-dependent diabetics: efficacy and safety of lacidipine versus nifedipine SR. ( Circo, A; D'Onofrio, V; Gulizia, M; Platania, F; Rizzini, P; Valenti, R, 1994) |
| "Carvedilol is a safe, efficient, once/day choice as monotherapy for mild to moderate essential hypertensive patients." | 2.67 | [Use of carvedilol compared to nifedipine in the treatment of mild and moderate essential arterial hypertension]. ( Dantas, M; Freitas, AF; Furtado, MR; Kohlmann, NE; Kohlmann, O; Plavnik, FL; Portela, JE; Spritzer, N; Spritzer, T, 1994) |
| "Fourteen subjects with untreated essential hypertension were subjected to 2-h water immersion (WI) study." | 2.67 | Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor. ( Coruzzi, P; Mossini, GL; Musiari, L; Novarini, A, 1993) |
| "Losartan (DuP 753) is a novel orally active angiotensin II antagonist that lowers blood pressure." | 2.67 | Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension. ( Carroll, J; Grossman, E; Peleg, E; Rosenthal, T; Shamiss, A, 1994) |
| " The analysis was further extended to simulate the blood pressure responses to alternative fixed dosage regimens." | 2.67 | Prediction and optimisation of the antihypertensive response to nifedipine. ( Donnelly, R; Elliott, HL; Meredith, PA, 1994) |
| " About 8% of patients had a low compliance rate, irrespective of the dosage regimen." | 2.67 | [Time of drug intake in hypertension and angina pectoris. A controlled monitoring study]. ( Erne, P; Heynen, G; Saxenhofer, H; Waeber, B, 1994) |
| " After 3 months the drug dosage was doubled if the systolic blood pressure goal (SBP < 160 mmHg and SBP reduction of at least 20 mmHg) had not been reached." | 2.67 | Antihypertensive efficacy and tolerability of different drug regimens in isolated systolic hypertension in the elderly. ( Alli, C; Avanzini, F; Bettelli, G; Colombo, F; Corso, R; Mariotti, G; Radice, M; Tognoni, G; Torri, V, 1994) |
| "Nifedipine was administered as capsules, nitrendipine was given from a small plastic tube (vial), containing 1 ml alcoholic solution." | 2.67 | Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules. ( Blanke, P; Reimnitz, P; Rohr, G, 1994) |
| "Nifedipine and captopril were administered as monotherapy in increasing dosage while a diuretic was added after 8 weeks in patients who failed to reach the target BP (24-h mean diastolic BP < 90 mm Hg) on monotherapy." | 2.67 | Nifedipine versus captopril in the management of moderate hypertension in black patients. ( Davis, J; Eitzman, L; Sareli, P; Skoularigis, J; Strugo, V, 1994) |
| "Treatment with enalapril for 48 months may have a beneficial effect on the decline of microalbumin excretion in NIDDM patients." | 2.67 | Effects of long-term enalapril treatment on persistent micro-albuminuria in well-controlled hypertensive and normotensive NIDDM patients. ( Hara, T; Hotta, N; Kawamura, T; Matsumae, H; Matsuo, S; Nakayama, M; Sakamoto, N; Sano, T; Sasaki, H, 1994) |
| "Of them 36 had dilated cardiomyopathy (DC), 30 ischemic heart disease (IHD), 19 suffered from essential hypertension (EH)." | 2.67 | [Differential use of vasodilators in various types of cardiac insufficiency]. ( Cheltsov, VV; Moiseev, VS; Shatkovskiĭ, NP, 1993) |
| "Prazosin was not recommended because of its low response rate." | 2.67 | Comparison of sublingual captopril, nifedipine and prazosin in hypertensive emergencies during hemodialysis. ( Huang, HW; Lin, CF; Lin, SL; Shiao, WY; Wu, SG; Yang, YH, 1993) |
| "Nisoldipine, which has a higher coronary vascular selectivity and less negative inotropism than nifedipine, is as effective and as well tolerated as nifedipine in patients whose hypertension is inadequately controlled on atenolol." | 2.67 | Comparison of nisoldipine and nifedipine as additional treatment in hypertension inadequately controlled by atenolol. ( Earle, KA; Hoffbrand, BI; Nievel, JG; Restrick, LJ; Simmonds, NJ, 1993) |
| " Dosing with 25 mg carvedilol once daily or 20 mg nifedipine SR twice daily resulted in mean peak reductions in supine blood pressure of 21/11 and 20/16 mm Hg, respectively, after 1 week of treatment with each respective monotherapy." | 2.67 | Safety of the coadministration of carvedilol and nifedipine sustained-release in the treatment of essential hypertension. ( de Vries Robles, P; Juttmann, JR; Venuti, RP, 1992) |
| "Amlodipine was associated with a significantly lower incidence of vasodilator-related adverse effects at initiation of therapy (headache, flushing, tachycardia) compared with nitrendipine, which may reflect its slower onset of action." | 2.67 | Amlodipine compared to nitrendipine in hypertensive patients: the effects on toleration in relationship to the onset of action. ( Borges, ET; Christeler, P; Guillaume-Gentil, M; Hollenstein, U; Mannhart, M; Waeber, B, 1992) |
| " Doxazosin produced rightward shifts of the PE pressor dose-response curves but had no effect on responses to AII." | 2.67 | Vascular pressor responses in treated and untreated essential hypertension. ( Donnelly, R; Elliott, HL; Howie, CA; Reid, JL; Sumner, DJ, 1990) |
| " Most adverse events were mild or moderate and the investigators' overall evaluation of tolerability was excellent or good for 91% of patients." | 2.67 | A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice. ( Varrone, J, 1991) |
| " Each drug was given separately in a random fashion in fixed dosage for 4 weeks with a washout period of 2 weeks in between the drugs." | 2.67 | The effects of antihypertensive agents on the quality of life in Indian hypertensives. ( Kumar, K; Rajan, AG; Somani, PN; Sundar, S, 1991) |
| "The effects of short- and long-term administration of nifedipine on serum lipids, lipoproteins, and apolipoproteins (apo) were studied." | 2.67 | Effects of short- and long-term administration of nifedipine on serum lipoprotein metabolism in patients with mild hypertension. ( Arakawa, K; Sasaki, J, 1990) |
| "Nifedipine was administered to 47 patients for 2 years, and the change of PWV was compared with age-matched control hemodialysis patients." | 2.67 | Effect of nifedipine administration on pulse wave velocity (PWV) of chronic hemodialysis patients--2-year trial. ( Hattori, Y; Okazawa, M; Saito, Y; Shirai, K; Uchino, J; Yoshida, S; Yoshida, T, 1990) |
| "Nilvadipine was well tolerated (only three patients were discontinued due to side effects)." | 2.67 | Evaluation of the clinical pharmacology of nilvadipine in patients with mild to moderate essential hypertension. ( Chen, CF; DeQuattro, V; Douglas, J; Saunders, E; Singh, S; Svetkey, LP; Vlachkis, ND; Weir, MR; Wiedl, SC; Woodward, DL, 1990) |
| "This randomized multicentre study in elderly hypertensives with two unbalanced groups (2 patients under labetalol for 1 patient under nifedipine) compared the efficacy and safety of labetalol, whose dosage could be adjusted (1, 2, then 3 tablets/day) according to blood pressure level (BP greater than or equal to 160/95 mmHg), to that of nifedipine given at its recommended dosage (2 tablets/day)." | 2.67 | [Hypertension in the elderly. Comparison of the efficacy and tolerability of labetalol and nifedipine. A multicenter, randomized, single-blind study]. ( d'Allens, H; Decoulx, M; Godon, P; Pappo, M, 1990) |
| " Sitting (and standing) blood pressure and heart rate one to four hours after dosing were recorded at entry (191/95 mmHg) and at the end of the run-in period (186/93 mmHg)." | 2.67 | Hypertension in the elderly: a study of a combination of atenolol and nifedipine. ( Cheadle, B; Duckett, GK, 1990) |
| "Nifedipine was slightly, but not significantly, more potent." | 2.67 | Verapamil versus nifedipine in slow-release preparations for the treatment of mild to moderate hypertension. ( Meisel, S; Nussinovitch, N; Rosenthal, T; Shamiss, A, 1990) |
| "2 mmHg) in pressure compared with pressures during placebo administration in both short- as well as long-term administration in group B patients." | 2.67 | Effect of calcium and calcium blockers in hypertension. ( Gupta, RK; Singh, RB; Singh, RG, 1990) |
| " The dosage of felodipine or nifedipine was doubled if seated diastolic blood pressure exceeded 95 mmHg, 2 or 4 weeks after randomisation." | 2.67 | Control of blood pressure in hypertensive patients with felodipine extended release or nifedipine retard. ( Littler, WA, 1990) |
| "Nifedipine did not cause significant changes in systolic or diastolic variability; a small but nonsignificant decrease in diastolic variability was seen with atenolol and the combination of atenolol and nifedipine." | 2.66 | Effect of calcium antagonists on ambulatory blood pressure and its variations. ( Clement, DL; De Pue, NY; Packet, L, 1987) |
| " Twenty-one patients with concentric LVH (thickness of interventricular septum, IVS, and left posterior wall, LPW, above 11 mm) were given a 2D and M-mode echocardiogram before (pre) and 12 and 24 weeks, respectively, after therapy was initiated (mean oral cl dosage 150 micrograms; nf, 30 mg/day)." | 2.66 | Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients. ( Brückner, S; Kleine, P; Meissner, E; von Bruchhausen, V, 1987) |
| "Amlodipine is a new long-acting calcium antagonist that has a long half-life and appears to be suitable for once-daily administration." | 2.66 | A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure in hypertensive patients. ( Allenby, KS; Burris, JF; Mroczek, WJ, 1988) |
| "Several drugs used in the treatment of hypertension have been shown to affect lipid metabolism." | 2.66 | Acute and chronic effects of dihydropyridines on triglycerides in humans. ( Cortese, C; Ferrara, LA; Gnasso, A; Mancini, M; Marotta, T; Pasanisi, F, 1988) |
| "Nitrendipine is a new calcium antagonist of the 1,4-dihydropyridine group with strong vasodilating properties." | 2.66 | Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate. ( Grosser, KD; Späh, F, 1988) |
| " Thus amlodipine administered once daily is an effective and safe agent for second-step therapy in mild to moderate essential hypertension." | 2.66 | Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension. ( Chrysant, SG; Glasser, SP; Graves, J; Koehn, DK; Rofman, B, 1989) |
| "Amlodipine treated patients had lower arterial pressures in both the supine and upright positions (P less than ." | 2.66 | Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide. ( Chrysant, C; Chrysant, SG; Hitchcock, A; Trus, J, 1989) |
| " Thus, there is evidence that application of concentration-effect analysis is useful in predicting the steady-state antihypertensive effect from the first dose-response to the drug." | 2.66 | Prediction of response to antihypertensive therapy with enalapril and nifedipine. ( Donnelly, R; Elliott, HL; Meredith, PA; Reid, JL, 1989) |
| "Amlodipine treatment was associated with a slightly higher incidence of side effects compared with placebo, but most of this difference was the result of edema, which was usually well tolerated." | 2.66 | The safety of amlodipine. ( Osterloh, I, 1989) |
| "We have assessed the efficacy and tolerance of Nifedipine twice daily and Nisoldipine once daily, both alone and in combination with a beta-blocker in 171 essential hypertensives in a randomized parallel comparison fashion." | 2.66 | The efficacy and tolerability of nifedipine (NIF) and nisoldipine (NIS) both alone and combined with a beta-blocker in patients with essential hypertension: a multicenter, parallel-group study. ( Rosenfeld, JB; Zabludowski, J, 1989) |
| "Nifedipine was associated with a significant increase in cardiac output and stroke volume at rest and at peak exercise, while propranolol decreased cardiac output at rest and at peak exercise." | 2.66 | Nifedipine, but not propranolol, improves left ventricular systolic and diastolic function in patients with hypertension. ( Boucher, CA; Christensen, DM; Federman, EB; Miller, DD; Ruddy, TD; Zusman, RM, 1989) |
| "Both nifedipine and enalapril were effective in lowering supine and erect systolic and diastolic BP, with nifedipine causing a significant (P less than 0." | 2.66 | A comparison of long acting nifedipine and enalapril in elderly hypertensives: a randomised, single-blind, cross-over study. ( Ewer, TC; Gilchrist, NL; Livesey, JH; Nicholls, MG; Sainsbury, R, 1988) |
| "Felodipine was generally well tolerated." | 2.66 | Antihypertensive effects of felodipine compared with placebo. ( Elmfeldt, D; Hedner, T, 1985) |
| "The felodipine treated patients experienced more ankle swelling and flushing than those in the hydralazine group who experienced more headache and minor gastro-intestinal upset." | 2.66 | Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group. ( , 1986) |
| "Foridon is not indicated for the treatment of renal hypertension." | 2.66 | [Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation]. ( Demidiuk, VT; Mikunis, RI; Monastyrskiĭ, IuI; Pshelutskiĭ, FF; Serkova, VK, 1988) |
| "Nitrendipine is a newly-developed calcium channel blocker derived from the dehydropyridine series which, according to experimental studies, affects marked dilation of the peripheral and coronary vessels." | 2.66 | [Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study]. ( Blasini, R; Brügmann, U; Reiniger, G; Rudolph, W, 1985) |
| "Bendroflumethiazide 5 mg was given to 17 patients with essential hypertension who had persistent mild to moderate hypertension despite treatment with nifedipine slow-release tablets 20 mg bid." | 2.66 | The effects of bendroflumethiazide added to nifedipine in patients with hypertension. ( Beevers, DG; Gill, JS; Zezulka, AV, 1987) |
| "Nifedipine is a calcium-channel blocker that produces vasodilatation and decreased peripheral resistance in humans." | 2.66 | Double-blind, placebo-controlled trial of twice-daily nifedipine as a step-2 agent in mild essential hypertension. ( Brown, TS; Deterding, J; Gavras, H; Gavras, I; Klotman, PE; Svetkey, LP; Weinberger, MH, 1987) |
| "Nifedipine was well tolerated and appeared to be an effective and safe drug in the treatment of acute rises of blood pressure in infants and children." | 2.66 | Blood pressure and hormonal responses to sublingual nifedipine in acute childhood hypertension. ( Bonzel, KE; Müller-Wiefel, DE; Rascher, W; Ruder, H; Schärer, K, 1986) |
| "Nifedipine therapy was associated with an increase in high-density lipoprotein cholesterol levels and a decrease in serum triglyceride levels." | 2.66 | Comparison of nifedipine and propranolol used in combination with diuretics for the treatment of hypertension. ( Christensen, D; Federman, E; Kochar, MS; McCarron, D; Porush, JG; Spitalewitz, S; Zusman, R, 1987) |
| " Both nisoldipine and the diuretic had a flat dose-response curve." | 2.66 | Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs. ( Daniels, AR; Opie, LH, 1987) |
| "Nicardipine was tolerated very well, and orthostatic hypotension was never observed." | 2.66 | Effect of nicardipine in elderly hypertensive patients. ( Bellet, M; Bouchacourt, P; Forette, F; Guerret, M; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1985) |
| "Hypertensive emergencies are a diverse group of disorders characterized by a marked elevation of systemic arterial pressure that is associated with acute end-organ dysfunction." | 2.66 | Efficacy and safety of sublingual nifedipine in hypertensive emergencies. ( Ault, MJ; Ellrodt, AG; Murata, GH; Riedinger, MS, 1985) |
| "The pharmacodynamic and pharmacokinetic profiles of nifedipine and nisoldipine were compared in a double blind, placebo-controlled study." | 2.66 | The pharmacodynamics and pharmacokinetics of a new calcium antagonist nisoldipine in normotensive and hypertensive subjects. ( Meredith, PA; Pasanisi, F; Reid, JL, 1985) |
| "Verapamil was discontinued in 2 patients who developed severe dyspnea at rest after 3-4 days of continued oral treatment." | 2.65 | Clinical use of calcium channel blockers as ventricular unloading agents. ( Agostoni, PG; Cipolla, C; Fabbiocchi, F; Guazzi, MD; Pepi, M; Sganzerla, P, 1983) |
| " The interaction of nifedipine and cimetidine is thus of clinical significance because of its pharmacodynamic effect." | 2.65 | [Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine]. ( Heidemann, H; Janisch, HD; Kirch, W; Ohnhaus, EE; Rämsch, K, 1983) |
| "Nifedipine is a simple, effective, and safe alternative drug for managing hypertensive emergencies, especially when continuous monitoring of the patient cannot be guaranteed." | 2.65 | Nifedipine in hypertensive emergencies. ( Bertel, O; Conen, D; Dubach, UC; Lang, C; Müller, J; Radü, EW, 1983) |
| "Nicardipine was given three times a day (mean dose: 69." | 2.65 | [Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine]. ( Bellet, M; Bouchacourt, P; Forette, F; Henry, JF; Hervy, MP; Poyard-Salmeron, C, 1984) |
| "In patients with chronic renal failure, decrement in BP was 25/16 mmHg (systolic and diastolic BP, respectively)." | 2.65 | [Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension]. ( Breuer, G; Kaufmann, W; Wambach, G, 1984) |
| "Nifedipine, 30 mg/day, was added and the dose was titrated upwards to 90 mg/day to achieve normal blood pressure." | 2.65 | The combination of propranolol and nifedipine in the treatment of hypertension: acute and long term effects. ( Ishay, DB; Kobrin, I; Leibel, B; Stessman, J; Yagil, Y, 1983) |
| "Pregnancy-induced hypertension is a major cause of maternal and fetal morbidity and mortality." | 2.61 | Hypertension and Pregnancy: Management and Future Risks. ( Jim, B; Reddy, S, 2019) |
| "Amlodipine has an inherently long pharmacokinetic half-life, whereas, in contrast, nifedipine has an inherently short half-life but in the GITS formulation the sophisticated delivery system allows for once-daily dosing." | 2.48 | Long-acting dihydropyridine calcium-channel blockers and sympathetic nervous system activity in hypertension: a literature review comparing amlodipine and nifedipine GITS. ( Elliott, HL; Meredith, PA; Toal, CB, 2012) |
| "Nifedipine is a dihydropyridine calcium-channel blocker (CCB) introduced approximately 30 years ago for the prophylaxis of angina symptoms, and then later utilized as an anti-hypertensive agent." | 2.45 | Review of nifedipine GITS in the treatment of high risk patients with coronary artery disease and hypertension. ( Beckey, C; Lundy, A; Lutfi, N, 2009) |
| "Calcium antagonists are used in the treatment of hypertension and angina." | 2.44 | The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension. ( Coca, A; Sierra, C, 2008) |
| "Hypertension is a global condition affecting billions worldwide." | 2.44 | Long-acting nifedipine in the management of the hypertensive patient. ( Nuzum, DS; Snider, ME; Veverka, A, 2008) |
| " However, the short-acting formulations of nifedipine had pharmacokinetic properties that were far from ideal and in 1995, several studies involving various dosing regimens reported possible dangerous effects in secondary prevention." | 2.44 | Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension. ( Dunselman, PH; Kragten, JA, 2007) |
| "Hypertension is an important modifiable risk factor for cardiovascular disease; its prevention and treatment currently represent major health concerns around the world, especially in western countries." | 2.43 | Use of nifedipine in the treatment of hypertension. ( Leoncini, G; Parodi, A; Pontremoli, R, 2005) |
| "Both drugs are used to treat hypertension, but only verapamil can be used to produce atrioventricular block in patients with atrial fibrillation." | 2.43 | Mechanism of tissue-selective drug action in the cardiovascular system. ( Barrett, TD; Maurice, DH; Triggle, DJ; Walker, MJ, 2005) |
| " It is desirable for antihypertensives to have a long duration of action so that once-daily dosing is possible." | 2.43 | Barnidipine: a new calcium channel blocker for hypertension treatment. ( Liau, CS, 2005) |
| "Nifedipine is a dihydropyridine calcium channel antagonist with predominantly vasodilatory activity." | 2.43 | Modified-release nifedipine: a review of the use of modified-release formulations in the treatment of hypertension and angina pectoris. ( Croom, KF; Wellington, K, 2006) |
| "Hypertension that complicates preeclampsia in pregnancy is a disorder that requires special consideration in both prevention and pharmacologic treatment." | 2.43 | Pathophysiology and medical management of systemic hypertension in preeclampsia. ( Frishman, WH; Schlocker, SJ; Tejani, N; Veresh, M, 2006) |
| " It compared the antihypertensive effect between increasing ARB dosage and the addition of controlled-release nifedipine." | 2.43 | [NICE-Combi study: effect of nifedipine in combination with an angiotensin II receptor blocker on BP control and renal protection]. ( Hasebe, N, 2006) |
| " The nifedipine gastrointestinal therapeutic system (GITS) formulation provides a once-daily dosing regimen with a continuous and slow release of the drug, resulting in a smooth plasma concentration/time profile." | 2.42 | Clinical use of nifedipine GITS in the treatment of hypertension: an overview. ( Levenson, J; Simon, A, 2003) |
| "The release of Adalat Oros 60 on the Belgian market was justified since it has been clearly demonstrated that the dosage of 60 mg significantly increases the proportion of responders to nifedipine monotherapy." | 2.42 | [Medication of the month. Adalat Oros 60 mg]. ( Kulbertus, H, 2004) |
| "Hypertension and hypercholesterolemia are frequently associated, and their treatment is proven to reduce cardiovascular risk." | 2.42 | Combined antihypertensive and lipid-lowering treatment. ( Cesari, M; Pessina, AC, 2004) |
| "High-altitude pulmonary edema is a non-cardiac edema that often precedes acute mountain sickness." | 2.42 | [Visiting high altitudes--healthy persons and patients with risk diseases]. ( Fischer, R, 2004) |
| "While nitroprusside is commonly used to treat severe hypertension, it is an extremely toxic drug that should only be used in rare circumstances." | 2.41 | The diagnosis and management of hypertensive crises. ( Marik, PE; Varon, J, 2000) |
| "Hypertension affects about 5% of western populations and in the majority of cases it is of unknown aetiology." | 2.41 | Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts. ( Dalton, GR; Evans, SJ; Levi, AJ, 2000) |
| " In contrast with several other calcium antagonists, barnidipine does not affect the steady-state kinetics of digoxin, whereas, like other calcium antagonists its bioavailability may be increased by the concomitant administration of cimetidine." | 2.41 | Interaction profile and tolerability of barnidipine. ( Beudeker, HJ; van der Aar, EM; van der Velden, JW, 2000) |
| "Nifedipine is an effective and safe drug to use when tocolytic therapy is indicated for preterm labor." | 2.41 | Calcium channel blockers in the management of preterm labor and hypertension in pregnancy. ( Bos, JM; Dekker, GA; Geijn, HP; Lok, CA; Papatsonis, DN, 2001) |
| " These differences can be attributed at least in part to the low catecholamine profile of verapamil and the marked rapid adrenergic activation with short-acting nifedipine, which could also explain the adverse effects found when this agent is given to patients with acute coronary syndromes." | 2.40 | Calcium channel blockers for hypertension: dissecting the evidence for adverse effects. ( Opie, LH, 1997) |
| " The interpretation of the results of these studies and their application to clinical practice requires an understanding of study design constraints, conflicting results and limitations in extrapolating study findings to other dosage strengths, formulations or agents within the calcium channel antagonist class." | 2.40 | Calcium channel antagonists: morbidity and mortality--what's the evidence? ( Parra, D; Straka, RJ; Swanson, AL, 1998) |
| "We still do not have an ideal drug to treat acute severe hypertension in pregnancy." | 2.40 | Management of acute severe hypertension and encephalopathy. ( Mabie, WC, 1999) |
| "The drug is equally effective in treating hypertension in elderly and younger patients and does not appear to adversely affect glucose or lipid metabolism." | 2.39 | Nilvadipine. A review of its pharmacodynamic and pharmacokinetic properties, therapeutic use in hypertension and potential in cerebrovascular disease and angina. ( Brogden, RN; McTavish, D, 1995) |
| "Nilvadipine is a new calcium antagonist of the the dihydropyridine group." | 2.39 | Nilvadipine: profile of a new calcium antagonist. An overview. ( Rosenthal, J, 1994) |
| " Thus, compared with other agents, amlodipine with its relatively smooth concentration-time profile and long elimination half-life will be superior in maintaining blood pressure control both with perfect compliance and when dosage regimens are perturbed due to missed drug doses." | 2.39 | Therapeutic coverage: reducing the risks of partial compliance. ( Elliott, HL; Meredith, PA, 1994) |
| " More controlled trials with less aggressive dosing regimens and placebo controls need to be performed to assess the most appropriate treatment for HUs with the fewest adverse effects." | 2.39 | Oral antihypertensives for hypertensive urgencies. ( Gales, MA, 1994) |
| "Amlodipine is an intrinsically long-acting, vasoselective calcium antagonist structurally related to nifedipine, but with unique binding and pharmacologic properties that distinguish it from other agents of this class." | 2.39 | Unique pharmacologic properties of amlodipine. ( Burges, R; Moisey, D, 1994) |
| "Felodipine is a highly vascular selective calcium entry blocker, with a vascular selectivity ratio greater than 100, as shown experimentally." | 2.39 | Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine. ( Cheng, CP; Elvelin, L; Little, WC; Nordlander, M, 1995) |
| "Nifedipine is a short-acting calcium antagonist formulated into several different oral preparations, each of which offers a distinct drug release profile." | 2.39 | The nifedipine gastrointestinal therapeutic system (GITS). Evaluation of pharmaceutical, pharmacokinetic and pharmacological properties. ( Foster, RT; Grundy, JS, 1996) |
| "Verapamil was associated with constipation." | 2.38 | Quality of life in the treatment of hypertension. The effect of calcium antagonists. ( Bulpitt, C; Fletcher, A, 1992) |
| "Nifedipine has both vasodilator and relaxant actions in arterial smooth muscle and other tissues, like uterus." | 2.38 | [Nifedipine in gynecology and obstetrics]. ( Palma-Aguirre, JA; Rodríguez-Palomares, C, 1992) |
| "Amlodipine is a dihydropyridine calcium antagonist drug with distinctive pharmacokinetic characteristics which appear to be attributable to a high degree of ionisation." | 2.38 | Clinical pharmacokinetics of amlodipine. ( Elliott, HL; Meredith, PA, 1992) |
| " Ambulatory monitoring studies have confirmed that once-daily dosing provides 24-h control of blood pressure." | 2.38 | Amlodipine in the treatment of hypertension. ( Kaplan, NM, 1991) |
| "A case or primary hyperaldosteronism due to unilateral macronodular adrenal hyperplasia is presented." | 2.38 | [Primary hyperaldosteronism caused by unilateral macronodular hyperplasia]. ( Bernardin, M; Chapuis, Y; Dorey, F; Fouchard, J; Louvel, A; Luton, JP, 1989) |
| "Nifedipine does cause a long-term reduction in sodium balance." | 2.38 | Nifedipine and systemic hypertension. ( MacGregor, GA, 1989) |
| "Verapamil was more often associated with conduction problems (up to 9%) and dyspnea or heart failure (up to 8%)." | 2.37 | Review of the cardiovascular adversity of the calcium antagonist beta-blocker combination: implications for antihypertensive therapy. ( Brouwer, RM; Bühler, FR; Follath, F, 1985) |
| " Blood pressure control shows a smooth profile over 24 h with once-daily dosing, and there is no tolerance with long-term administration of the drug." | 2.37 | Amlodipine in hypertension: an overview of the clinical dossier. ( Julius, S, 1988) |
| "Diltiazem may increase glomerular filtration rate via attenuation of the intrarenal effects of angiotensin II or norepinephrine." | 2.37 | Effects of calcium entry blockers on renin-angiotensin-aldosterone system, renal function and hemodynamics, salt and water excretion and body fluid composition. ( Bauer, JH; Reams, G; Sunderrajan, S, 1985) |
| "Nisoldipine is an orally administered calcium entry blocking drug structurally related to nifedipine." | 2.37 | Nisoldipine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of angina pectoris, hypertension and related cardiovascular disorders. ( Friedel, HA; Sorkin, EM, 1988) |
| " The elimination half-life of all 3 prototypical calcium antagonists is probably significantly prolonged during long-term dosing with clinically effective regimens." | 2.37 | Kinetics and dynamics of calcium entry antagonists in systemic hypertension. ( Hamann, SR; McAllister, RG; Schloemer, GL, 1986) |
| "Nifedipine generally has little depressant action in this setting and usually improves cardiac function, especially if the sympathetic reflexes are intact." | 2.37 | Use of calcium antagonists in ventricular dysfunction. ( Josephson, MA; Singh, BN, 1985) |
| "Treatment with nifedipine can safely be combined with administration of a beta receptor blocking agent." | 2.36 | Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem. ( Henry, PD, 1980) |
| "Clinical experience in the treatment of hypertension with this class of agents is confined to verapamil, nifedipine, and diltiazem." | 2.36 | Calcium antagonists. Clinical use in the treatment of systemic hypertension. ( Frishman, WH; Ocken, S; Spivack, C, 1983) |
| " The activation of the adrenergic and renin angiotension systems seen after nifedipine administration is less pronounced after chronic administration of the drug and is nearly absent after verapamil and diltiazem." | 2.36 | [Calcium antagonists in the therapy of hypertension]. ( Heidbreder, E; Heidland, A; Hörl, WH; Schäfer, RM, 1983) |
| "A review of the pathophysiology and treatment of pre-eclampsia indicates that vasospasm and vascular hyperreactivity are important elements in the disease process and its control." | 2.36 | Possible treatment of pre-eclampsia with calcium channel blocking agents. ( Zaret, GM, 1983) |
| "Amiodarone is an extremely potent drug which is effective for both supraventricular as well as ventricular arrhythmias." | 2.36 | New antiarrhythmic drugs. ( Hess, DS; Scheinman, MM, 1983) |
| " Therapy success: systolic blood pressure ~140 mm Hg and diastolic blood pressure ~90 mm Hg, therapy failure: persistent systolic blood pressure ≥ 160 or diastolic blood pressure ≥ 110 mm Hg after maximum dosage of therapy (EL)." | 1.91 | Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia. ( Dong, W; Peng, Z; Xiao, Y; Zhang, J, 2023) |
| "Arterial hypertension is among factors with the potential for increasing the risk of cognitive impairment in elderly subjects." | 1.72 | Delayed Decline of Cognitive Function by Antihypertensive Agents: A Cohort Study Linked with Genotype Data. ( Hojnacki, D; Podolsky, R; Schaller, B; Sternberg, Z; Tian, M; Yu, J, 2022) |
| "The purpose of this research work was to evaluate the Pharmacokinetic (PK), Pharmacodynamic (PD), and the distribution pattern of mucoadhesive microspheres of nifedipine." | 1.62 | Pharmacokinetic and Pharmacodynamic Studies of Nifedipine Loaded Microspheres for the Treatment of Hypertension. ( Garg, R; Gupta, GD; Lal, C, 2021) |
| "Hypertension is a major risk factor for cerebrovascular disease." | 1.62 | Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats. ( Gao, W; Liu, C; Liu, X; Liu, Y; Luo, C; Man, S, 2021) |
| "Nifedipine was resumed during periodontal treatment when the patient's hypertension worsened." | 1.62 | Treatment of calcium channel blocker-induced gingival overgrowth without modifying medication. ( Miyashita, Y; Morikawa, S; Nakagawa, T; Nasu, M, 2021) |
| "TCMs combined with Nifedipine sustained-release tablets group generated a total 20-year cost of 11,517." | 1.56 | Cost-effectiveness analysis of combining traditional Chinese medicine in the treatment of hypertension: compound Apocynum tablets combined with Nifedipine sustained-release tablets vs Nifedipine sustained-release tablets alone. ( Feng, S; Guo, J; Hu, M; Liu, QB; Xu, Q; Yang, N, 2020) |
| "Once hypertension is established, increased mechanical stretch stress becomes a leading cause of vascular remodeling." | 1.46 | Role of nifedipine and hydrochlorothiazide in MAPK activation and vascular smooth muscle cell proliferation and apoptosis. ( Bardeesi, ASA; Deng, L; Guo, Y; Li, C; Li, Y; Li, Z; Liu, K; Liu, S; Pei, T; Ping, S; Sheng, P; Wang, H; Wang, J; Zhou, Y, 2017) |
| " On top of the previous stable treatment regimen (which excluded calcium-channel blockers), a 10 mg dosing of barnidipine hydrochloride at bedtime was added to all subjects during a 12-week period." | 1.43 | Effect of bedtime dosing of barnidipine hydrochloride in non-dipper hypertensive patients with obstructive sleep apnoea not treated with continuous positive airway pressure. ( Bravi, E; Cassi, A; Crippa, G; Zabzuni, D, 2016) |
| "Treatment with rutin and quercetin ameliorated the effects of high salt diet on these biochemical indices." | 1.40 | Rutin and quercetin show greater efficacy than nifedipin in ameliorating hemodynamic, redox, and metabolite imbalances in sodium chloride-induced hypertensive rats. ( Akindahunsi, AA; Akinmoladun, AC; Crown, OO; Olaleye, MT, 2014) |
| "Nifedipine is a widely used anti-anginal and anti-hypertensive agent." | 1.40 | Nifedipine-induced histological changes in the parotid glands of hypertensive rats. ( Daskala, I; Kotsiou, A; Seferos, N; Tesseromatis, C; Tsamouri, M, 2014) |
| "Although continuous intravenous (IV) calcium infusion is recommended for calcium channel blocker (CCB) overdose, its clinical efficacy is inconsistent and the dosage required is unclear." | 1.39 | A novel dosing regimen for calcium infusion in a patient of massive overdose of sustained-release nifedipine. ( Li, GQ; Liu, Y; Wei, LQ; Zhou, H, 2013) |
| " On the other hand, under the condition of Ang II-induced hypertension, administration of a hypotensive dosage of cilnidipine showed no effect on the plasma aldosterone levels, whereas a hypotensive dosage of nifedipine significantly increased the plasma aldosterone levels." | 1.38 | L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action. ( Aritomi, S; Konda, T; Yoshimura, M, 2012) |
| "Efforts to increase the awareness and treatment of hypertension in the population at large may lower the incidence of hypertensive crisis and its complications." | 1.37 | Dutch guideline for the management of hypertensive crisis -- 2010 revision. ( Beutler, JJ; de Gooijer, A; Gaillard, CA; Kroon, AA; van den Born, BJ; van den Meiracker, AH, 2011) |
| " Chronic administration (45 days) produced no toxic effects in vital organs and systems of Wistar rats and ISIAH rats." | 1.37 | Glycidipine, a promising hypotensive and cardioprotective agent. ( Belenichev, IF; Bryzgalov, AO; Khvostov, MV; Pavlov, SV; Tolstikova, TG, 2011) |
| " To evaluate the contribution of Gi-proteins and L-VDCC to vasoconstriction induced by exogenous norepinephrine, dose-response curves were determined before and after acute nifedipine administration." | 1.36 | Role of nifedipine-sensitive sympathetic vasoconstriction in maintenance of high blood pressure in spontaneously hypertensive rats: effect of Gi-protein inactivation by pertussis toxin. ( Karen, P; Kunes, J; Pintérová, M; Zicha, J, 2010) |
| "Hypertension was induced by DOCA-salt." | 1.35 | Synthesis and pharmacological investigation of 3-(substituted 1-phenylethanone)-4-(substituted phenyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates. ( Bhole, RP; Bhusari, KP; Chikhale, RV; Khedekar, PB, 2009) |
| " Hypertensive patients received daily treatment with an oral dosage of 30 mg nifedipine GITS for 16 days." | 1.35 | Arg347Cys polymorphism of alpha1A-adrenoceptor gene is associated with blood pressure response to nifedipine GITS in Chinese hypertensive patients. ( Hong, X; Huo, Y; Liu, H; Xu, X; Zhang, Y, 2009) |
| " In both age groups, chronic nifedipine administration reduced neurogenic contractions of isolated superior mesenteric artery, but did not significantly affect the dose-response curve to exogenous noradrenaline in 8-week-old rats." | 1.35 | Effect of chronic nifedipine treatment on blood pressure and adrenergic responses of isolated mesenteric artery in young rats with developing spontaneous hypertension. ( Török, J; Zemančíková, A, 2009) |
| "The treatment with nifedipine in the CIH group attenuated blood pressure (159+/-2 mm Hg; P<0." | 1.35 | Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels. ( Gozal, D; Gu, Y; Nozdrachev, AD; Ortines, RV; Prabhu, SD; Soukhova-O'Hare, GK, 2008) |
| " Dosing 3 mg/kg/d cediranib for 4 days induced a marked hypertension of 35 to 50 mmHg." | 1.35 | Inhibition of vascular endothelial growth factor-a signaling induces hypertension: examining the effect of cediranib (recentin; AZD2171) treatment on blood pressure in rat and the use of concomitant antihypertensive therapy. ( Curwen, JO; Kendrew, J; Musgrove, HL; Ogilvie, DJ; Richmond, GH; Wedge, SR, 2008) |
| "Nifedipine, a dihydropyridine calcium antagonist, improves endothelial function in patients with hypercholesterolaemia by enhancing nitric oxide (NO) activity, and increases endothelial NO bioavailability by antioxidant mechanisms." | 1.34 | Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus. ( Inami, N; Iwasaka, T; Kimura, Y; Nishikawa, M; Nomura, S; Omoto, S; Shouzu, A, 2007) |
| " Nifedipine, a dihydropyridine-type calcium antagonist, improves endothelial function in hypercholesterolemia by enhancing nitric oxide function, and increases endothelial nitric oxide bioavailability by antioxidative mechanisms." | 1.33 | Long-term treatment with nifedipine modulates procoagulant marker and C-C chemokine in hypertensive patients with type 2 diabetes mellitus. ( Iwasaka, T; Nishikawa, M; Nomura, S; Omoto, S; Shouzu, A, 2005) |
| " Once-daily dosing with nifedipine GITS has been shown to achieve smooth and continuous blood pressure control, identical to conventional first-line diuretic therapy." | 1.33 | Nifedipine gastrointestinal therapeutic system--hypertension management to improve cardiovascular outcomes. ( Heagerty, AM, 2005) |
| "Nifedipine was intravenously administered at a dose of 1 mg/kg." | 1.33 | Diminished responses to nifedipine imply severe end-organ damage in spontaneously hypertensive rats. ( Cai, GJ; Lu, LH; Shen, FM; Su, DF; Xie, HH, 2005) |
| "Essential hypertension is associated with several alterations in arterial function." | 1.33 | Increased wall tension in response to vasoconstrictors in isolated mesenteric arterial rings from patients with high blood pressure. ( Kähönen, M; Kööbi, P; Mäki-Jouppi, J; Mustonen, J; Nordback, I; Pörsti, I; Sand, J; Tahvanainen, A; Taurio, J, 2006) |
| "Nifedipine was the most frequently prescribed antihypertensive (44." | 1.32 | Inadequate control of blood pressure in Nigerians with diabetes. ( Okoro, EO; Oyejola, BA, 2004) |
| " Medical records (from five Canadian pediatric hospitals) of all pediatric hypertensive hospitalized children who were treated with short-acting nifedipine from January 1995 to December 1998 were retrospectively reviewed for patient demographics, dosing regimen, use of concomitant medications, co-morbid conditions, and presence/absence of minor and serious adverse events." | 1.32 | The safety and use of short-acting nifedipine in hospitalized hypertensive children. ( Filler, G; Girardin, C; Goodyer, P; Gowrishankar, M; Harley, F; MacLaine, P; Midgley, J; Ogborn, M; Orrbine, E; Rosychuk, RJ; Yiu, V, 2004) |
| " We report two cases that developed cerebrovascular and cardiovascular adverse events associated with aggressive treatment of increased blood pressure by the use of sublingual nifedipine capsule." | 1.32 | Adverse events associated with aggressive treatment of increased blood pressure. ( Akay, S; Ayrik, C; Cevik, AA; Yanturali, S, 2004) |
| "Enalapril was able to prevent the increase in LV and kidney weights (p=0." | 1.31 | A comparative study of morphological changes in spontaneously hypertensive rats and normotensive Wistar Kyoto rats treated with an angiotensin-converting enzyme inhibitor or a calcium-channel blocker. ( Jurjus, AR; Saleh, FH, 2001) |
| "Nifedipine treatment decreased circulating plasma lipoperoxides and isoprostanes and increased plasma antioxidant capacity." | 1.31 | Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension. ( Favilla, S; Ghiadoni, L; Magagna, A; Pompella, A; Salvetti, A; Taddei, S; Virdis, A, 2001) |
| " glabra saponins at a dosage of 200mg/Kg of body weight." | 1.31 | [Antihypertensive effect of Herniaria glabra saponins in the spontaneously hypertensive rat]. ( Cherrah, Y; Hassar, M; Lyoussi, B; Rhiouani, H; Settaf, A, 2001) |
| "The cost of treating hypertension represents a substantial percentage of total pharmacy expenditures at medical centers and by managed care organizations in the United States." | 1.31 | Pharmacist-managed hypertension therapy conversion. ( Yanchick, JK, 2001) |
| "Nifedipine was used in 553 (95." | 1.31 | Use of oral antihypertensive medication preceding blood pressure elevation in hospitalized patients. ( de Macedo, CR; de Macedo, JM; Lopes, AA; Noblat, AC; Noblat, L, 2001) |
| " There have been few case reports of adverse events in children." | 1.31 | Evaluation of the safety of short-acting nifedipine in children with hypertension. ( Deming, DD; Egger, DW; Hamada, N; Perkin, RM; Sahney, S, 2002) |
| " Relative bioavailability was significantly increased with Eudragit nanoparticles compared to the nifedipine/PEG solution." | 1.30 | The antihypertensive effect of orally administered nifedipine-loaded nanoparticles in spontaneously hypertensive rats. ( Atkinson, J; Fluckiger, L; Hoffman, M; Kim, YI; Lartaud-Idjouadiene, I; Maincent, P, 1997) |
| " The hypotensive effect of YM430 reached its maximum about 2 hr after dosing and lasted for over 10 hr." | 1.30 | Hypotensive effects of YM430, a 1,4-dihydropyridine derivative, in spontaneously hypertensive rats and renal hypertensive dogs. ( Shibasaki, K; Takenaka, T; Takizawa, K; Uchida, W, 1997) |
| "Type 2 diabetes is increasing in prevalence and is predominantly managed in general practice." | 1.30 | A cautionary tale. ( Phillips, PJ; Popplewell, PY; Tallis, GA, 1997) |
| "Hypertension was diagnosed based on the clinic BP." | 1.30 | Evaluation of the antihypertensive effect of barnidipine, a dihydropyridine calcium entry blocker, as determined by the ambulatory blood pressure level averaged for 24 h, daytime, and nighttime. Barnidipine Study Group. ( Abe, K; Imai, Y; Nishiyama, A; Sekino, M; Yoshinaga, K, 1997) |
| "Gingival overgrowth was noticed in 29% of the patients." | 1.30 | The clinical effects of nifedipine on periodontal status. ( Caglayan, F; Caglayan, G; Eratalay, K; Tavassoli, S; Yamalik, N, 1998) |
| "To compare the effects of chronic administration of two dihydropyridines, nifedipine and amlodipine, and the non-dihydropyridine Ca2+ antagonist mibefradil on fluid filtration of large arteries and extravasation of albumin in spontaneously hypertensive rats." | 1.30 | Different effects of calcium antagonists on fluid filtration of large arteries and albumin permeability in spontaneously hypertensive rats. ( Koen, R; Lacolley, P; Levy, BI; Poitevin, P, 1998) |
| " The results obtained show that Adalat in dosage 60 mg daily during 7 days is most effective in cases with concomitant border-line hypertension." | 1.30 | [Premedication with different groups of hypotensive drugs in preparation of patients with concomitant arterial hypertension to planned surgical treatment]. ( Eliutin, DV; Mil'tsyn, AS; Sadchikov, DV, 1998) |
| "Hypertension is frequently associated to abdominal obesity, and hyperinsulinism could play a role in its pathogenesis." | 1.30 | Effects of 3-month nifedipine treatment on endocrine-metabolic parameters in patients with abdominal obesity and mild hypertension. ( Avogadri, E; Camanni, F; Ghigo, E; Grottoli, S; Maccario, M; Oleandri, SE; Procopio, M; Rossetto, R, 1998) |
| " The suitability of barnidipine for once-daily dosing was confirmed in a randomized, double-blind, placebo-controlled, crossover study of 20 patients." | 1.30 | Efficacy and tolerability of once-daily barnidipine in the clinical management of patients with mild to moderate essential hypertension. ( Spieker, C, 1998) |
| " As a group, the principal (type I) adverse effects of these drugs relate to the pharmacological action of calcium channel blockade, namely vasodilation, and include dizziness, flushing, palpitations and peripheral oedema." | 1.30 | Diversity and intensity of adverse events in the treatment of hypertension with barnidipine. ( Beudeker, HJ; Nishi, M; van der Velden, JW, 1998) |
| "Nifedipine treatment for 5 days significantly reduced the blood pressure in cadmium-hypertensive and normotensive rats." | 1.30 | The effects of short-term nifedipine treatment on responsiveness of aortic rings of cadmium-hypertensive rats. ( Oğütman, C; Ozdem, SS, 1999) |
| "The hypertension resolved after the intussusception was reduced." | 1.30 | [Hypertensive manifestation of an acute intestinal intussusception]. ( Bourdat-Michel, G; Durand, C; Paget, C; Rossignol, AM, 1999) |
| "Postmortem examination confirmed congestive heart failure with chronic, fibrosing cardiomyopathy similar to that in other gorillas." | 1.30 | Chronic hypertension with subsequent congestive heart failure in a western lowland gorilla (Gorilla gorilla gorilla). ( Barnhart, JS; Bell, MD; Miller, CL; Schwartz, AM, 1999) |
| " Co-administration with propranolol markedly decreased the heart rate, but little affected the heart weight, suggesting changes in the heart rate during the long-term administration of KW-3049 did not largely affect cardiac hypertrophy." | 1.29 | Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats. ( Deguchi, T; Hara, T; Hattori, O; Kato, Y; Saijyo, T; Suzuki, K; Tanaka, H, 1993) |
| "Nifedipine treatment significantly prevented STZ-induced increase in cholesterol and triglyceride levels." | 1.29 | Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats. ( Bangaru, RA; Gandhi, TP; Goyal, RK; Satia, MC; Shah, TS, 1995) |
| "Acute myocardial infarction is characterized by a more pronounced rise in plasma ANP concentration in hypertensive patients than in those without a history of hypertension." | 1.29 | Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction. ( Górecki, A; Ignatowska-Switalska, H; Januszewicz, A; Kochanowski, J; Lapiński, M; Opolski, G; Stolarz, P; Słomka, K; Wocial, B, 1995) |
| " These results suggested that AJ-2615 has potential as a long-acting (once daily dosage regimen) antihypertensive drug without causing a steep blood pressure fall and tachycardia." | 1.29 | Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals. ( Fukuya, F; Hosoki, K; Ikeno, A; Karasawa, T; Minato, H; Nose, I; Takeyama, K, 1993) |
| " Pharmacokinetic parameters were as follows: Cmax, 59." | 1.29 | [Effects of slow-release nifedipine on hemodynamics and pharmacokinetics in elderly hypertensives]. ( Nakamura, H; Shimamoto, H; Shimamoto, Y, 1994) |
| "Mild to moderate hypertension is usually asymptomatic and therefore the impact on quality of life and side-effects of the antihypertensive treatment can have a negative effect on treatment compliance." | 1.29 | Quality of life in hypertension. ( Os, I, 1994) |
| "Hypertension was treated with enalapril, enalapril and nifedepine and nifedepine alone." | 1.29 | Proteinuria in essential hypertension. ( Doifode, DV; Kate, SK; Soni, PS, 1994) |
| "Hypertension is commonly associated with an endothelial dysfunction that may contribute to the rise in blood pressure." | 1.29 | Impairement of endothelium-dependent relaxation in chronic two-kidney, one clip hypertensive rats. ( Choi, KC; Kang, YJ; Kim, WJ; Lee, J; Park, JW; Woo, YJ; Yoo, KJ; Yoo, KS, 1994) |
| "Treatment with nifedipine resulted in a prolongation of segment length." | 1.29 | Effect of nifedipine on coronary capillary geometry in normotensive and hypertensive rats. ( Cicutti, N; Kazda, S; Rakusan, K; Turek, Z, 1994) |
| "Hypertension was examined as an independent variable for its effect on patient outcome." | 1.29 | Case management in cerebral revascularization. ( Edwards, WH; Hoyle, RM; Jenkins, JM; Martin, RS; Mulherin, JL, 1994) |
| "Indomethacin treatment did not affect the mastoparan contraction even though mastoparan has been shown to stimulate phospholipase A2 in other cell types." | 1.29 | Enhanced vascular reactivity to mastoparan, a G protein activator, in genetically hypertensive rats. ( Kanagy, NL; Webb, RC, 1994) |
| "Gingival hyperplasia was only weakly related to plaque and calculus but was unrelated to CsA dose (mg/kg/day), duration of CsA therapy (months), CsA blood or saliva levels (ng/ml), or the concurrent administration of a Nif or Dz." | 1.29 | Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists. ( Francis, DM; Fullinfaw, R; Higgins, TJ; King, GN; Walker, RG; Wiesenfeld, D, 1993) |
| "Atenolol was initiated in 7." | 1.29 | Implementation of local guidelines for cost-effective management of hypertension. A trial of the firm system. ( Aron, DC; Aucott, JN; Dombrowski, R; Fuehrer, SM; Laich, J; Pelecanos, E, 1996) |
| " Good response was noted in corinfar-retard combination with Cordanum in patients with moderate hemodynamic changes, hypertonicity of sympathoadrenal system, tachycardia." | 1.29 | [The clinical efficacy of Korinfar-retard in combination with Cordanum, triampur and Capoten in patients with arterial hypertension]. ( Chil'tsov, VV; Ignat'ev, VG; Kukes, VG; Pavlov, SS; Pavlova, LI; Privalov, AN; Rumiantsev, AS, 1996) |
| "Nifedipine was the most efficient drug in inhibiting the rise in intracellular calcium ion concentration ([Ca2+]i) when added in vitro and in neutrophils of patients receiving this drug, whereas verapamil had no significant effect." | 1.29 | Inhibited neutrophil functions in patients treated with nifedipine but not with verapamil or diltiazem. ( Levy, R; Nagauker-Shriker, O; Schlaeffer, F, 1996) |
| "Hypertension was associated with enhanced pressor response, whereas the diabetic state counteracted this effect." | 1.29 | Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| " In conclusion, isolated mesenteric arteries from obese Zucker rats do not show relevant structural changes, and the pharmacodynamic behaviour of such vessels appears to be the same as that of control preparations." | 1.29 | Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats. ( Kam, KL; Pfaffendorf, M; van Zwieten, PA, 1996) |
| " For both drug classes, we suggest that long-acting agents be considered, providing therapeutic coverage well beyond the normal dosing interval." | 1.29 | 1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart? ( Leenen, FH, 1996) |
| "3-3 mg/kg), dose-response curves of the antihypertensive effect did not change and body weight gain was equal to that of the vehicle-treated group." | 1.28 | Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs. ( Haruno, A; Kanda, A; Miyake, H; Nagasaka, M, 1992) |
| "Nilvadipine appears to be an effective hypotensive agent at single daily doses of 8 mg." | 1.28 | Nilvadipine in hypertension with renal dysfunction. ( Albert, FW; Berger, HH, 1992) |
| "The results confirm that effective treatment of hypertension significantly reduced basal [Ca2+]i in platelets but raise doubts whether elevated basal [Ca2+]i is necessarily the sole mechanism by which the sensitivity of platelets to aggregatory agents is increased in hypertension." | 1.28 | Treatment of hypertension induces a fall in platelet basal cytoplasmic calcium concentration without influencing platelet aggregation. ( Baig, MW; Davies, JA; Lees, AD; Orchard, MA; Perrins, EJ; Prentice, CR; Wilson, J, 1992) |
| "Indomethacin pretreatment caused an apparent dose-related increase in pressor responses in all animals." | 1.28 | Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension. ( Hamilton, CA; Huang, YT; Reid, JL, 1992) |
| "Hypertension is a known risk factor in the genesis of coronary artery disease." | 1.28 | Influence of mild to moderate treated hypertension on 9-11 year mortality in patients with pre-existing coronary heart disease. ( Gupta, KD; Gupta, R; Kasliwal, P, 1992) |
| "Nifedipine was added at 10 weeks of age." | 1.28 | Dietary sodium and the antihypertensive effect of nifedipine in spontaneously hypertensive rats. ( Leenen, FH; Yuan, B, 1992) |
| "When hypertension was treated with corinfar, the activity of COD and GP was increased by 10 and 18%, respectively." | 1.28 | [Changes in the activity of antioxidant enzymes in patients with hypertension]. ( Iarema, NI; Konovalova, GG; Lankin, VZ, 1992) |
| "Verapamil was more effective than nifedipine in improving natriuresis and ANP release to saline load and in lowering the albumin excretion rate." | 1.28 | Effects of angiotensin converting enzyme inhibitors and calcium antagonists on atrial natriuretic peptide release and action and on albumin excretion rate in hypertensive insulin-dependent diabetic patients. ( Abaterusso, C; Brocco, E; Carraro, A; Cipollina, MR; Fioretto, P; Frigato, F; Muollo, B; Riva, F; Trevisan, M; Velussi, M, 1992) |
| "Amlodipine is a low-clearance, dihydropyridine calcium antagonist." | 1.28 | Pharmacokinetics and pharmacodynamics of amlodipine. ( Abernethy, DR, 1992) |
| "Nifedipine is a calcium channel antagonist." | 1.28 | [The use of intravenous nifedipine for the treatment of severe hypertensive crisis. A clinical case]. ( Fabbrini, GP; Grassi, P; Maione, M; Mazzi, C; Nannicini, P, 1992) |
| "Moderate pyridoxine deficiency in rats has been shown to induce hypertension, which can be corrected by pyridoxine supplementation." | 1.28 | Increased calcium influx in caudal artery of rats made hypertensive with pyridoxine deficiency. ( Bose, R; Dakshinamurti, K; Viswanathan, M, 1991) |
| " Administration of nifedipine to Sprague-Dawley and WKY rats did not affect the dose-response curve to AVP, but nifedipine administration in SHR led to a significant inhibition of the pressor responses to AVP." | 1.28 | Pressor actions of arginine vasopressin in pithed Sprague-Dawley, Wistar-Kyoto and spontaneously hypertensive rats before and after treatment with nifedipine or pertussis toxin. ( Tabrizchi, R; Triggle, CR, 1991) |
| "Treatment of severe hypertension is beneficial, but reversibility of target-organ damage has not been characterized." | 1.28 | Effect of nifedipine GITS on left ventricular mass and diastolic function in severe hypertension. ( Ardeljan, M; Eison, HB; Garbowit, DL; Goldman, ME; Krakoff, LR; Phillips, RA; Shimabukuro, S, 1991) |
| "Concomitantly, cardiac hypertrophy was attenuated in the treated group compared with the placebo group (heart-to-body weight ratios of 4." | 1.28 | Vascular injury: mechanisms and manifestations. ( Nayler, WG, 1991) |
| "2 mg/kg/day for 20 days) chronically receiving AML, there was an enhancement of the antihypertensive effect of AML within a few days after starting chronic dosing, and thereafter a significant reduction of BP at 24 hr after dosing and constant effects of AML during subsequent treatment." | 1.28 | [Antihypertensive effects of amlodipine, a new calcium antagonist]. ( Ishiko, J; Munehasu, S; Suzuki, M; Yamanaka, K, 1991) |
| " Chronic administration of YM-09730-5 (3 mg/kg) reduced the severity of glomerular lesions in the kidney and vasculitis in the mesenteric artery." | 1.28 | Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats. ( Fujimoto, K; Inagaki, O; Kawashima, K; Oohata, H; Suzuki, T; Toda, H, 1991) |
| " It was found that in a part of patients the long-term administration of antihypertensive drugs led to an increased accumulation of kynurenine as a manifestation of pyridoxal-5-phosphate deficiency." | 1.28 | Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension. ( Liepinja, DJ; Rudzite, VK; Silava, AK; Vitols, AV, 1990) |
| "Nifedipine (1 mg/kg ip) was equally effective in preventing the increase in MBP caused by endothelin, norepinephrine, or ANG II." | 1.28 | Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin. ( Anania, V; Demontis, MP; Madeddu, P; Manunta, P; Pazzola, A; Soro, A; Tonolo, G; Troffa, C; Varoni, MV; Yang, XP, 1990) |
| " Patients treated with cyclosporine and prednisone alone had their cyclosporine dosage adjusted to maintain their cyclosporine level between 400 and 900 ng/mL between 1 and 6 months following transplantation." | 1.28 | The effect of calcium channel blockers on the cyclosporine dose requirement in renal transplant recipients. ( Babcock, S; Chan, L; Howard, RL; Shapiro, JI, 1990) |
| "Nifedipine was withdrawn due to a considerable increase in heart rate in three patients and skin allergy in one." | 1.28 | Acute and long-term treatment of hypertension with nifedipine in the elderly. ( Czarnecka, D; Dubiel, JP; Grodzicki, T; Kawecka-Jaszcz, K; Kocemba, J; Skalska, A; Skoczen, M; Witek, J, 1990) |
| "Hypokalemia was found by normal urine excretion of potassium and normal intraerythrocyte potassium contents." | 1.28 | [Hypokalemia caused by nifedipine]. ( Angelova, I; Kundurdzhiev, A; Popiliev, I, 1990) |
| "Hypertension is a frequent complication of a scorpion's sting in children, and specific antihypertensive therapy is indicated in severe cases." | 1.28 | Vasodilators and hypertensive encephalopathy following scorpion envenomation in children. ( Gueron, M; Sofer, S, 1990) |
| "Nifedipine appears to be a promising agent for the prehospital treatment of severe hypertension, but its proper role is not yet defined." | 1.28 | Prehospital use of nifedipine for severe hypertension. ( Duda, J; Heller, MB; Kaplan, R; Maha, RJ; Menegazzi, J; Paris, PM; Stewart, RB, 1990) |
| "Nifedipine did not produce any depression of contractile and pump functions of the heart." | 1.28 | [Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects]. ( Bobrov, VA; Konoshevich, SN, 1989) |
| "Hypertension was not observed in rats fed with a vitamin D-deficient diet or treated with streptozotocin." | 1.28 | [Pharmacological study on blood pressure in rats with bone disorders]. ( Shamoto, T, 1989) |
| "In the kidney, hypertension is associated with a compensatory shift in the autoregulatory response to pressure." | 1.28 | Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats. Studies in the isolated perfused hydronephrotic kidney. ( Epstein, M; Hayashi, K; Loutzenhiser, R, 1989) |
| "Nifedipine is an effective agent in acute hypertensive episodes, even in patients receiving chronic calcium-channel blocker therapy." | 1.28 | Nifedipine in the treatment of hypertensive episodes in the coronary care unit. ( Hilleman, DE; Malesker, MA; Mohiuddin, SM; Mooss, AN; Rovang, KS; Sketch, MH, 1989) |
| "Hypertension was developed in 5-week-old male rats fed a low calcium diet, which evokes hypocalcemia and nutritional hyperparathyroidism, for 2 weeks." | 1.28 | Elevation of blood pressure in young rats fed a low calcium diet. Effects of nifedipine and captopril. ( Arai, M; Matsumoto, S; Nagatsu, T; Shamoto, T; Togari, A, 1989) |
| "Pretreatment with captopril in a dose of 25 mg." | 1.28 | Captopril--nifedipine interaction in hypertension. ( Dadkar, VN; Dhar, HL; Khokhani, RC; Moulick, ND, 1989) |
| " Also on long-term administration of NIF in hypertensive patients, renal function improved." | 1.28 | [The effects of nifedipine on blood pressure and renal function]. ( Igarashi, N, 1989) |
| " These preliminary data suggest that in patients with severe hypertension, effective long-term control of BP with a once-a-day dosage of nifedipine in the GITS formulation may be achieved without adverse hemodynamic effects." | 1.28 | Cardiac and hemodynamic adjustments to rapid and sustained blood pressure reduction. ( Ardeljan, M; Eison, HB; Goldman, ME; Krakoff, LR; Phillips, RA, 1989) |
| "Nifedipine treatment resulted in variable improvement in tardive dyskinesia in eight geriatric psychiatric patients." | 1.28 | Calcium channel blockers for tardive dyskinesia in geriatric psychiatric patients. ( Kushnir, SL; Ratner, JT, 1989) |
| "In nifedipine-treated rats, the pressor actions of guanabenz and clonidine were virtually abolished, while the onset of the depressor responses were significantly accelerated." | 1.27 | Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats. ( Lappe, RW; Saslow, BA; Wendt, RL, 1984) |
| " Adverse reactions may be reduced by the use of long-acting nifedipine, which would permit a reduction in the dosage of captopril and minoxidil." | 1.27 | Long acting nifedipine in the treatment of severe hypertension. ( Bursztyn, M; Grossmann, E; Rosenthal, T, 1984) |
| " As revealed by the dose-response curves in SHR both drugs produce similar maximal drops in blood pressure by about 54%." | 1.27 | Differential influence of the calcium antagonist nitrendipine and the vasodilator hydralazine on normal and elevated blood pressure. ( Garthoff, B; Knorr, A, 1984) |
| " These results suggest that the rate of absorption of this drug varies widely among individuals." | 1.27 | Specific HPLC assay for serum nifedipine. ( Fernandez, PG; Galway, BA; Kim, BK; Snedden, W, 1984) |
| "Fifteen males with previously untreated essential hypertension in WHO stage I, aged 20-64 years were studied on an outpatient basis." | 1.27 | Haemodynamic effects of nifedipine in essential hypertension at rest and during exercise. ( Lund-Johansen, P; Omvik, P, 1983) |
| "When felodipine was given as single drug to 14 previously untreated hypertensives in a single-blind manner, BP was rapidly reduced by about 15% while HR increased by 25%." | 1.27 | Short-term effects of felodipine, a new dihydropyridine, in hypertension. ( Aberg, H; Andersson, O; Bengtsson, C; Elmfeldt, D; Haglund, K; Hedner, T; Ostman, J; Seideman, P; Sjöberg, KH; Strömgren, E, 1984) |
| "Nitrendipine is a calcium antagonistic 1,4-dihydropyridine derivative with a pronounced antihypertensive activity in animal experiment." | 1.27 | Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension. ( Garthoff, B; Kazda, S; Knorr, A, 1983) |
| "Nine patients with untreated, essential hypertension (mean casual blood pressure 173/109 +/- 14/7 mmHg (+/- s." | 1.27 | The effect of nifedipine on arterial pressure and reflex cardiac control. ( Littler, WA; McLeay, RA; Stallard, TJ; Watson, RD, 1983) |
| "They also have great potential for the treatment of hypertension, cerebrovascular disorders, and Raynaud's phenomenon." | 1.27 | Calcium channel blocking drugs. Part II: Clinical applications. ( Brill, DM; Fozzard, HA, 1985) |
| "Nifedipine was less efficacious in relaxing the contractile response to Bay k 8644 compared to the contractile response to K+ in SHRs femoral arteries." | 1.27 | Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats. ( Aoki, K; Asano, M; Matsuda, T, 1986) |
| "Amlodipine is a long-acting dihydropyridine-based calcium antagonist developed for use on a once-a-day basis." | 1.27 | The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload. ( Nayler, WG, 1988) |
| " amlodipine, clearance tended to be decreased in elderly as compared with young patients with resulting prolongation in elimination half-life (64 +/- 20 vs." | 1.27 | Amlodipine in elderly hypertensive patients: pharmacokinetics and pharmacodynamics. ( Abernethy, DR; Gutkowska, J; Lambert, MD, 1988) |
| "Felodipine, a new dihydropyridine, was given to 58 hypertensive patients in combination with an adrenergic beta-receptor antagonist and a diuretic agent." | 1.27 | Long term experience of felodipine in combination with beta-blockade and diuretics in refractory hypertension. ( Collste, P; Danielsson, M; Elmfeldt, D; Feleke, E; Gelin, A; Hedner, T; Rydén, L, 1985) |
| " Nine patients were treated for 42 days at a fixed dosage of 1 tablet/day." | 1.27 | [Nitrendipine, a new calcium antagonist, in the therapy of arterial hypertension]. ( Aimi, M; Bianco, C; Conti, G; Corbacelli, C; Cosmi, F; Mollaioli, M; Ricca, M, 1985) |
| "To be considered ideal for the treatment of hypertension, a class of drugs should produce a maintained reduction of arterial pressure primarily through a fall in total peripheral resistance that is at least uniformly distributed through the organ circulations of the target organs of hypertensive vascular disease." | 1.27 | Hemodynamic effects of calcium entry-blocking agents in normal and hypertensive rats and man. ( Frohlich, ED, 1985) |
| "Nifedipine therapy was associated with an improved LV filling in nearly all cases of HCM and HHD, and in some cases of IHD." | 1.27 | [Stress pulsed Doppler echocardiography in the evaluation of diastolic left ventricular function]. ( Asai, M; Fukuda, N; Ishimoto, T; Mori, H; Niki, T; Ohkushi, H; Oki, T; Taoka, M; Tominaga, T, 1985) |
| "In hypertensive cardiac hypertrophy, the elevated coronary perfusion pressure compensates importantly for the raised coronary resistance." | 1.27 | Electrocardiographic alterations suggestive of myocardial injury elicited by rapid pressure lowering in hypertension. ( Alimento, M; Guazzi, MD; Maltagliati, A; Pepi, M; Tosi, E, 1988) |
| "Thus nifedipine was better than glyceryl trinitrate for the control of post-sternotomy hypertension in patients with good left ventricular function." | 1.27 | Influence of glyceryl trinitrate and nifedipine on coronary sinus blood flow and global myocardial metabolism during coronary artery operation. ( Bovill, JG; Fiolet, JW; Koolen, JJ; Patrick, MR; van der Stroom, JG; van Wezel, HB, 1986) |
| " After nifedipine, both the mSBP and the mDBP decreased, with onset of effect five minutes after dosage and maximum decrease at 60 min (mSBP 134." | 1.27 | Treatment of hypertensive crisis in children with nifedipine. ( Albajara, L; Cagigas, P; Garcia, S; Lopez-Herce, J; Ruza, F, 1988) |
| "Treatment with nifedipine in combination with furosemide and propranolol led to a more significant decrease in calcium responses than that expressed with monotherapy." | 1.27 | Platelets as a model for studying the action of antihypertensive drugs. ( Avdonin, PV; Kravchenko, AN; Mazaev, AV; Nekrasova, AA; Shkhvatsabaya, IK, 1988) |
| "The treatment with nifedipine induced a significant reduction in both systolic and diastolic blood pressures; the infusions of angiotensin II (0." | 1.27 | Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients. ( Leonetti, G; Terzoli, L; Zanchetti, A, 1987) |
| "Nifedipine was administered to treat arterial hypertension (greater than 180 mm Hg, systolic)." | 1.27 | Effects of nifedipine on intracranial pressure in neurosurgical patients with arterial hypertension. ( Sano, T; Suzuki, T; Takeshita, H; Tateishi, A; Tokuno, H, 1988) |
| "Two women with preeclampsia treated unsuccessfully with alpha-methyldopa and magnesium sulfate became profoundly hypotensive when oral nifedipine was added." | 1.27 | Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia? ( Cámera, MI; Martinotti, A; Mayorga, LM; Vignolo, CA; Waisman, GD, 1988) |
| "Nifedipine was given for 20 weeks, mixed into commercial rat chow (0." | 1.27 | Improved myocardial capillarisation in spontaneously hypertensive rats treated with nifedipine. ( Hoofd, L; Kazda, S; Kubat, K; Rakusan, K; Turek, Z, 1987) |
| "When nifedipine was given to patients already on bendrofluazide, there was an additional fall in blood pressure." | 1.27 | Nifedipine, sodium intake, diuretics, and sodium balance. ( Cappuccio, FP; MacGregor, GA; Markandu, ND; Pevahouse, JB, 1987) |
| "Nifedipine was more potent in inhibiting the contraction to K+ and serotonin in WKY diabetic arteries as compared with WKY controls." | 1.27 | Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery. ( Agrawal, DK; McNeill, JH, 1987) |
| "Treatment of hypertension in systemic lupus erythematosus (SLE) may be complicated by unwanted immunologic vascular and renal side effects of drugs." | 1.27 | Nifedipine in the treatment of hypertension in systemic lupus erythematosus. ( Bursztyn, M; Many, A; Rosenthal, T, 1987) |
| "Urgent hypertension is defined by severe elevations of blood pressure without associated end-organ damage." | 1.27 | Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department. ( Catapano, MS; Marx, JA, 1986) |
| "When verapamil or nifedipine were added prior to and during Ca2+ repletion, the force developed was reduced to 25% of that of uninhibited contraction." | 1.27 | Ca2+ influx in spontaneously hypertensive rats is sensitive to calcium antagonists. ( Heinle, H; Lindner, V, 1987) |
| " All patients received 20 mg nifedipine, in slow-release tablet form, twice daily; at Week 4, dosage was increased to 40 mg twice daily in 8." | 1.27 | The antihypertensive efficacy of nifedipine alone and in combination in general practice. ( Duffy, J; Macdonald, G, 1987) |
| "The serum concentrations and urinary excretion of nifedipine and 3 of its metabolites have been compared in two groups of hypertensive patients, one receiving prolonged (1-2 years) nifedipine monotherapy, the second receiving the same dosage of nifedipine in conjunction with a variety of other antihypertensive and cardioactive drugs." | 1.27 | The metabolism of nifedipine during long-term therapy. ( Fernandez, PG; Nath, C; Snedden, W, 1986) |
| " Following long term administration of felodipine cardiac output remained elevated owing to an increase in stroke volume." | 1.27 | Haemodynamic effects of short and long term administration of felodipine in spontaneously hypertensive rats. ( Nordlander, M, 1985) |
| "Treatment with nifedipine inhibited both the development of hypertension and this specific change in the plasma proteins, in spite of continuous dietary salt loading." | 1.27 | Characteristic changes of plasma proteins in the Dahl hypertensive rat strain (DS) during the development of hypertension. ( Garthoff, B; Morich, FJ, 1985) |
| "Nifedipine monotherapy was problematic because of side-effects and development of resistance to therapy after a few months." | 1.26 | Long-term therapy of arterial hypertension with nifedipine given alone or in combination with a beta-adrenoceptor blocking agent. ( Christensen, CK; Husted, SE; Lederballe Pedersen, O; Nielsen, HK, 1982) |
| "When nifedipine was given to rats at a dosage of 0." | 1.26 | Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine. ( Hall, CE; Hungerford, S, 1982) |
| " Substantial and prolonged falls in blood pressure were observed following oral dosing with 3 mg/kg of nifedipine in renal hypertensive rats, with 10 mg/kg of nifedipine in normotensive and spontaneously hypertensive rats and with 10 mg/dg of hydralazine in all three groups of animals." | 1.26 | Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats. ( Fujie, K; Kubo, T; Misu, Y; Yamashita, M, 1981) |
| "The hypotensive effect of nifedipine (a Ca2+-antagonist) was studied in acute tests and during the long-term administration of the drug together with propranolol." | 1.26 | Hypotensive action of nifedipine (Ca2+-antagonist) and propranolol in acute trials and its long-term therapy of hypertensive coronary heart disease patients. ( Aoki, K; Kato, K; Kawaguchi, Y; Kondo, S; Mochizuki, A; Sato, K; Yamamoto, M, 1981) |
| " The findings indicate that different regulatory mechanisms are activated during acute and chronic administration of nifedipine." | 1.26 | Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension. ( Christensen, NJ; Kornerup, HJ; Mikkelsen, E; Pedersen, EB; Pedersen, OL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1027 (40.18) | 18.7374 |
| 1990's | 974 (38.11) | 18.2507 |
| 2000's | 353 (13.81) | 29.6817 |
| 2010's | 156 (6.10) | 24.3611 |
| 2020's | 46 (1.80) | 2.80 |
| Authors | Studies |
|---|---|
| Rovnyak, GC | 1 |
| Atwal, KS | 1 |
| Hedberg, A | 1 |
| Kimball, SD | 1 |
| Moreland, S | 1 |
| Gougoutas, JZ | 1 |
| O'Reilly, BC | 1 |
| Schwartz, J | 1 |
| Malley, MF | 1 |
| Shanklin, JR | 1 |
| Johnson, CP | 1 |
| Proakis, AG | 1 |
| Barrett, RJ | 1 |
| Kurokawa, M | 1 |
| Sato, F | 1 |
| Fujiwara, I | 1 |
| Hatano, N | 1 |
| Honda, Y | 2 |
| Yoshida, T | 5 |
| Naruto, S | 1 |
| Mastumoto, J | 1 |
| Uno, H | 1 |
| Kukla, MJ | 1 |
| Breslin, HJ | 1 |
| Gill, A | 2 |
| Carson, JR | 1 |
| Almond, HR | 1 |
| Brannan, MD | 1 |
| Carmosin, RJ | 1 |
| Flaim, SF | 1 |
| Gleason, MM | 1 |
| Keely, SL | 1 |
| Ludovici, DW | 1 |
| Pitis, PM | 1 |
| Evans, JM | 1 |
| Fake, CS | 1 |
| Hamilton, TC | 1 |
| Poyser, RH | 1 |
| Watts, EA | 1 |
| Chikhale, RV | 1 |
| Bhole, RP | 1 |
| Khedekar, PB | 1 |
| Bhusari, KP | 1 |
| Alam, O | 1 |
| Khan, SA | 1 |
| Siddiqui, N | 1 |
| Ahsan, W | 1 |
| Verma, SP | 4 |
| Gilani, SJ | 1 |
| Seto, SL | 1 |
| Barra, ME | 1 |
| Hamidi, A | 1 |
| Sin, JH | 1 |
| Devine, LT | 1 |
| Liang, L | 1 |
| Kung, JY | 1 |
| Mitchelmore, B | 1 |
| Cave, A | 1 |
| Banh, HL | 1 |
| Yin, J | 1 |
| Mei, Z | 1 |
| Shi, S | 1 |
| Du, P | 1 |
| Qin, S | 1 |
| Bastian, IN | 1 |
| Antony, KM | 1 |
| Wu, HZ | 1 |
| Cheng, Y | 1 |
| Yu, D | 1 |
| Li, JB | 1 |
| Jiang, YF | 1 |
| Zhu, ZN | 1 |
| Tung, YC | 2 |
| Lin, CP | 2 |
| Hsiao, FC | 2 |
| Ho, CT | 2 |
| Tzyy-Jer, H | 1 |
| Chu, YC | 2 |
| Chen, WJ | 2 |
| Chu, PH | 2 |
| Lee, HW | 1 |
| Huang, CC | 1 |
| Leu, HB | 1 |
| Lin, YJ | 1 |
| Kikuchi, D | 1 |
| Obara, T | 1 |
| Miura, R | 1 |
| Suzuki, N | 1 |
| Hirakawa, H | 1 |
| Josaka, R | 1 |
| Ito, M | 1 |
| Tokunaga, M | 1 |
| Usui, K | 1 |
| Okada, K | 1 |
| Hollingworth, SA | 1 |
| Ankrah, D | 1 |
| Uzochukwu, BSC | 1 |
| Okeke, CC | 1 |
| Ruiz, F | 1 |
| Thacher, E | 1 |
| Greene, NH | 1 |
| Pon, FF | 1 |
| Kilpatrick, SJ | 2 |
| Do, SC | 1 |
| Leonard, SA | 1 |
| Kan, P | 1 |
| Panelli, DM | 1 |
| Girsen, AI | 1 |
| Lyell, DJ | 1 |
| El-Sayed, YY | 1 |
| Druzin, ML | 1 |
| Herrero, T | 1 |
| van de Vusse, D | 1 |
| Mian, P | 2 |
| Schoenmakers, S | 1 |
| Flint, RB | 1 |
| Visser, W | 1 |
| Allegaert, K | 1 |
| Versmissen, J | 2 |
| Taguchi, R | 1 |
| Shigemi, D | 1 |
| Yasunaga, H | 1 |
| Wautlet, CK | 1 |
| Hoffman, MC | 1 |
| Cleary, EM | 1 |
| Racchi, NW | 1 |
| Patton, KG | 1 |
| Kudrimoti, M | 1 |
| Costantine, MM | 1 |
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| Shao, Y | 1 |
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| Zhang, X | 2 |
| Sternberg, Z | 1 |
| Podolsky, R | 1 |
| Yu, J | 1 |
| Tian, M | 1 |
| Hojnacki, D | 1 |
| Schaller, B | 1 |
| Lovgren, T | 3 |
| Connealy, B | 2 |
| Yao, R | 2 |
| D Dahlke, J | 2 |
| Zohny, YM | 1 |
| Awad, SM | 1 |
| Rabie, MA | 1 |
| Al-Saidan, OA | 1 |
| Fishel Bartal, M | 1 |
| Blackwell, SC | 1 |
| Pedroza, C | 1 |
| Lawal, D | 1 |
| Amro, F | 1 |
| Samuel, J | 1 |
| Chauhan, SP | 3 |
| Sibai, BM | 3 |
| Chang, CM | 1 |
| Chen, YC | 1 |
| Wu, WT | 1 |
| Lin, TK | 1 |
| Chou, YC | 1 |
| Lin, MH | 1 |
| Sun, CA | 1 |
| Tayag, JCS | 1 |
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| Kokuba, S | 1 |
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| Shiohira, H | 1 |
| Nakamura, K | 4 |
| Wasif, U | 1 |
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| Lo, DF | 1 |
| Wei, Y | 1 |
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| Liu, G | 3 |
| Ashworth, D | 1 |
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| Bick, D | 1 |
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| Nelson-Piercy, C | 3 |
| Sparkes, J | 1 |
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| Webb, A | 1 |
| Wilson, H | 1 |
| Myers, J | 2 |
| Chappell, LC | 3 |
| Yoselevsky, EM | 1 |
| Seely, EW | 1 |
| Celi, AC | 1 |
| Robinson, JN | 1 |
| McElrath, TF | 1 |
| Bhat, AD | 1 |
| Keasler, PM | 1 |
| Kolluru, L | 1 |
| Dombrowski, MM | 1 |
| Palanisamy, A | 1 |
| Singh, PM | 1 |
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| Xiao, Y | 1 |
| Dong, W | 1 |
| Webster, LM | 2 |
| Reed, K | 1 |
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| Patel, P | 1 |
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| Salama, M | 1 |
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| Gaber, W | 1 |
| Hamza, H | 1 |
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| Gamal, A | 1 |
| Abdallah, S | 1 |
| de Heus, RAA | 3 |
| Olde Rikkert, MGM | 3 |
| Tully, PJ | 1 |
| Lawlor, BA | 3 |
| Claassen, JAHR | 3 |
| Hoorn, EJ | 1 |
| Blazevic, A | 1 |
| Rabelink, NM | 1 |
| Liu, W | 1 |
| Liu, Y | 5 |
| Fu, J | 2 |
| Saade, GR | 1 |
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| Kantorowska, A | 1 |
| Heiselman, CJ | 1 |
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| Elsayad, A | 1 |
| Muscat, JC | 1 |
| Sicuranza, GB | 1 |
| Vintzileos, AM | 1 |
| Heo, HJ | 1 |
| Bellos, I | 1 |
| Pergialiotis, V | 1 |
| Papapanagiotou, A | 1 |
| Loutradis, D | 1 |
| Daskalakis, G | 1 |
| Amssayef, A | 1 |
| Ajebli, M | 1 |
| Eddouks, M | 1 |
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| Umair, M | 1 |
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| Saeed, H | 1 |
| Saleem, Z | 1 |
| Tauqeer, F | 1 |
| Sardesai, M | 1 |
| Shende, P | 1 |
| Santa-Helena, E | 1 |
| Cabrera, DDC | 1 |
| D'Oca, MGM | 1 |
| Scaini, JLR | 1 |
| de Oliveira, MWB | 1 |
| Werhli, AV | 1 |
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| Kalar, I | 1 |
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| Secnik, J | 1 |
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| Dennison, D | 1 |
| Pulimond, BM | 1 |
| Bondarenko, IP | 1 |
| Dubinskiĭ, AA | 1 |
| Pasieshvili, LM | 1 |
| Matsuda, S | 1 |
| Ueda, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Nifedipine XL Versus Placebo for the Treatment of Preeclampsia With Severe Features During Induction of Labor[NCT04392375] | Phase 4 | 110 participants (Actual) | Interventional | 2020-06-09 | Completed | ||
| A European Multicentre Double-blind Placebo-controlled Phase III Trial of Nilvadipine in Mild to Moderate Alzheimer's Disease[NCT02017340] | Phase 3 | 511 participants (Actual) | Interventional | 2013-04-24 | Completed | ||
| A Comparative Study for the Effects of Nifedipine GITS and Amlodipine Besylate on Recovery of Blood Pressure Rhythm and Arterial Stiffness in the Young and Middle-aged Subjects With Non-dipper Hypertension[NCT02940548] | Phase 4 | 99 participants (Actual) | Interventional | 2016-12-31 | Terminated (stopped due to The patient recruitment and follow-ups were influenced with the pandemic of COVID-19) | ||
| A 12 Weeks, Multi-center, Open Label, Randomized, Active Drug Parallel Control Trial to Compare the Effectiveness of Valsartan/Amlodipine and Nifedipine in Treating Chinese Hypertensive Patients Not Respond to Mono Antihypertensive Treatment[NCT01167153] | Phase 4 | 564 participants (Actual) | Interventional | 2010-05-31 | Completed | ||
| Effectiveness and Tolerability of Long-Acting Nifedipine Gastrointestinal Therapeutic System in Chronic Kidney Disease With Uncontrolled Hypertension Patients, a Prospective, Multicenter, Observational Study[NCT03194633] | 871 participants (Actual) | Observational | 2017-07-10 | Completed | |||
| A Randomized Control Trial of Furosemide or Placebo With Usual Antihypertensives in the Antepartum Management of Severe Hypertension With Wide Pulse Pressure[NCT04615624] | Phase 3 | 65 participants (Actual) | Interventional | 2021-01-04 | Completed | ||
| A Multicenter, Double-blind, Parallel-group Comparative Study Between Oral BAYA1040_CR 80 mg and 40 mg for 8 Weeks in Patients With Essential Hypertension for Whom Oral BAYA1040_CR 40 mg is Insufficient[NCT01287260] | Phase 3 | 352 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| A Multicenter, Multifactorial, Randomized, Double-Blind, Placebo-Controlled Dose-Finding Study of Nifedipine GITS and Candesartan in Combination Compared to Monotherapy in Adult Patients With Essential Hypertension[NCT01303783] | Phase 2 | 1,381 participants (Actual) | Interventional | 2011-04-30 | Completed | ||
| AdADOSE - Antihypertensive Treatment With Adalat® in Different Doses and Combination Therapy[NCT01118286] | 4,497 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| Evaluation of Some Emerging Biomarkers of Cardiovascular Risk Stratification in Hypertensive Patients: a 5-years Follow-up[NCT02064218] | 0 participants | Observational | 2007-11-30 | Recruiting | |||
| A Prospective, Open-label, Active-controlled, Randomized Study Comparing Nifedipine GITS Versus Valsartan Versus a Combination of Both on Central Blood Pressure in Inadequately Controlled Essential Hypertension.[NCT01071122] | Phase 4 | 365 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| Comparison of Oral Nifedipine to Oral Labetolol for the Management of Severe Postpartum Hypertension[NCT02168309] | 50 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| Amlodipine Versus Nifedipine ER for the Management of Postpartum Hypertension: A Randomized Controlled Noninferiority Trial[NCT04790279] | Phase 4 | 132 participants (Actual) | Interventional | 2021-04-09 | Completed | ||
| Post Kidney Transplant Nocturnal Hypertension Prevalence and Management Study[NCT01120613] | 0 participants (Actual) | Interventional | 2010-04-30 | Withdrawn (stopped due to primary investigator left institution; not enough patients) | |||
| A Multicenter Study Evaluating the Efficacy of Nifedipine GITS - Telmisartan Combination in Blood Pressure Control and Beyond: Comparison of Two Treatment Strategies.[NCT00750113] | Phase 4 | 405 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
| THE EFFECTS OF SITAXSENTAN ONCE DAILY DOSING ON PROTEINURIA, 24-HOUR BLOOD PRESSURE, AND ARTERIAL STIFFNESS IN SUBJECTS WITH CHRONIC KIDNEY DISEASE[NCT00810732] | Phase 2 | 27 participants (Actual) | Interventional | 2007-05-09 | Completed | ||
| Randomized,Open-label,Parallel Design Comparator Study of Effect of Nifedipine GITS/OROS (Adalat) 30 mg in Combination With Valsartan (Diovan) 80 mg Compared to Valsartan (Diovan) 160 mg Monotherapy in Patients Whose Blood Pressure is Not Well Controlled [NCT00993109] | Phase 4 | 360 participants (Actual) | Interventional | 2010-02-28 | Completed | ||
| the Effect of Nifedipine Controlled Release Tablets in Hypertensive Patients on Chronic Maintenance Hemodialysis and the Influence of Hemodialysis on the Plasma Concentration of Nifedipine[NCT01021501] | Phase 4 | 20 participants (Anticipated) | Interventional | 2009-12-31 | Not yet recruiting | ||
| The Antihypertensives and Vascular, Endothelial and Cognitive Function Trial (AVEC Trial)[NCT00605072] | Phase 2 | 53 participants (Actual) | Interventional | 2008-01-31 | Completed | ||
| Brain Changes in Pediatric Obstructive Sleep Apnea[NCT05368077] | 70 participants (Anticipated) | Interventional | 2022-05-14 | Recruiting | |||
| Alternative in Beta Blocker Intolerance; the ABBI Trial[NCT00893984] | Phase 4 | 6 participants (Actual) | Interventional | 2009-05-31 | Terminated (stopped due to Lack of patient recruitment) | ||
| Effects of Change in Blood Pressure on Retinal Capillary Rarefaction in Patients With Arterial Hypertension - a Pilot Study[NCT06098300] | 30 participants (Anticipated) | Observational | 2023-09-01 | Recruiting | |||
| A Comparison of Fetal Hemodynamic Measurements Between Pregnant Women Taking Anti-hypertensive Medication and Controls[NCT00759278] | 0 participants (Actual) | Observational | 2008-08-31 | Withdrawn (stopped due to No participants) | |||
| [NCT00000542] | Phase 3 | 0 participants | Interventional | 1993-08-31 | Completed | ||
| [NCT00005332] | 0 participants | Observational | 1991-09-30 | Completed | |||
| Fixed-Dose Combination of Perindopril/Amlodipine (Amlessa®) and Fixed-Dose Combination of Perindopril/Indapamide /Amlodipine (Co-Amlessa®) - Contribution to Management in Newly Diagnosed and Uncontrolled Hypertensive Patients[NCT03738761] | Phase 4 | 471 participants (Actual) | Interventional | 2018-02-13 | Completed | ||
| The Pathophysiology and Treatment of Supine Hypertension in Patients With Autonomic Failure[NCT00223717] | Phase 1 | 152 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| A Pivotal Study To Evaluate The Effectiveness of Isometric Handgrip Therapy In Prehypertensive And Hypertensive Patients[NCT04467879] | 146 participants (Actual) | Interventional | 2020-06-01 | Terminated (stopped due to New Protocol and Outcome Measures in Review) | |||
| Emergency Department Interventions to Improve Blood Pressure Follow-up[NCT00798551] | 10 participants (Actual) | Interventional | 2008-04-16 | Completed | |||
| A Phase II, Randomized, Single-Blind, Controlled Clinical Trial to Evaluate the Efficacy and Safety of Hemolink[Tm] (o-Raffinose Cross-Linked Human Hemoglobin) in Subjects Undergoing Primary Coronary Artery Bypass Grafting Surgery[NCT00038454] | Phase 2/Phase 3 | 180 participants | Interventional | Suspended | |||
| A Triple Blinded Randomized Controlled Trial of Oral Melatonin in Elevated Blood Pressure Individual (MRCTEBP)[NCT03764020] | Phase 3 | 320 participants (Anticipated) | Interventional | 2019-06-01 | Not yet recruiting | ||
| Comparison of Single and Combination Diuretics in Low-Renin Hypertension[NCT02351973] | Phase 4 | 423 participants (Actual) | Interventional | 2009-11-30 | Active, not recruiting | ||
| Manidipine Versus Amlodipine in Patients With Hypertension: Effects on Peripheral Edema Evaluated by Bioimpedance Analysis[NCT03106597] | Phase 4 | 46 participants (Actual) | Interventional | 2015-08-20 | Terminated (stopped due to Difficulty in enrolling subjects) | ||
| South Danish Hypertension and Diabetes Study[NCT01062763] | Phase 3 | 119 participants (Actual) | Interventional | 2010-03-31 | Completed | ||
| Prevalence and Incidence of Dyskalemia in Hypertensive Patients Initiating a Fixed Dose Combination Pill of Telmisartan and Amlodipine[NCT05155436] | Phase 4 | 1,090 participants (Actual) | Interventional | 2022-01-15 | Completed | ||
| Is Procardia XL 60 mg Q Daily Equivalent to 30 mg XL Given Twice Daily?[NCT03595982] | Phase 4 | 5 participants (Actual) | Interventional | 2018-09-15 | Terminated (stopped due to Low enrollment) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
(NCT04392375)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 20 |
| Placebo | 19 |
(NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 8 |
| Placebo | 6 |
Measured acute antihypertension therapy between enrollment and delivery (NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| Nifedipine 30MG | 18 |
| Placebo | 27 |
(NCT04392375)
Timeframe: At delivery
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Cesarean Delivery | Vaginal Delivery | |
| Nifedipine 30MG | 11 | 42 |
| Placebo | 17 | 32 |
Some participants could have more than one indication for Cesarean Delivery. (NCT04392375)
Timeframe: Between enrollment and delivery, assessed up to 18 weeks
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| First stage arrest | Second stage arrest | Nonreassuring fetal status | Worsening maternal status | |
| Nifedipine 30MG | 8 | 1 | 3 | 2 |
| Placebo | 6 | 5 | 7 | 1 |
The sitting blood pressure was trough value (23-26 hours after drug administration) measured by sphygmomanometer. Blood pressure was measured on both arms and the arm with higher msDBP was used at visit 1 and following visits. Measurement of blood pressure was carried out 3 times at each visit on the selected arm. The results and mean value of three sitting blood pressures were recorded for analysis. (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | mm Hg (Mean) |
|---|---|
| Valsartan/Amlodipine | -8.5 |
| Nifedipine | -4.8 |
The sitting blood pressure was trough value (23-26 hours after drug administration) measured by sphygmomanometer. Blood pressure was measured on both arms and the arm with higher mean sitting diastolic blood pressure (MSDBP) was used at visit 1 and following visits. Measurement of blood pressure was carried out 3 times at each visit on the selected arm. The results and mean value of three sitting blood pressures were recorded for analysis. (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | mm Hg (Mean) |
|---|---|
| Valsartan/Amlodipine | -16.8 |
| Nifedipine | -10.6 |
Orthostatic pulse was measured by sphygmomanometer when subject stood for 1 minute at clinic during each visit. (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | beats/min (Mean) |
|---|---|
| Valsartan/Amlodipine | -0.6 |
| Nifedipine | 0.4 |
Sitting pulse was measured by sphygmomanometer after subject sat for 5 minutes at clinic during each visit. (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | beats/min (Mean) |
|---|---|
| Valsartan/Amlodipine | -1.1 |
| Nifedipine | 0.0 |
Blood Pressure (BP) target was defined as mean sitting BP<140/90 mm Hg in non-diabetic patients and<130/80 mm Hg in diabetic patients at 12 weeks. (NCT01167153)
Timeframe: 12 weeks
| Intervention | Percentage of participants (Number) |
|---|---|
| Valsartan/Amlodipine | 79.03 |
| Nifedipine | 57.36 |
The arm with higher sitting blood pressure was selected for all examinations throughout the study. Orthostatic blood pressure was measured when subject stood for 1 minute. Orthostatic blood pressures were measured at screening and each visit. (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | mm Hg (Mean) | |
|---|---|---|
| Orthostatic diastolic blood pressure | Orthostatic systolic blood pressure | |
| Nifedipine | -3.3 | -8.6 |
| Valsartan/Amlodipine | -7.2 | -13.3 |
"Effective SBP control rate was defined as proportion of subjects in whom MSSBP < 140 mmHg or MSSBP reduction ≥ 20 mmHg from baseline.~Effective DBP control rate was defined as proportion of subjects in whom MSDBP < 90 mmHg or MSDBP reduction ≥10 mmHg from baseline." (NCT01167153)
Timeframe: Baseline, 12 weeks
| Intervention | Percentage of participants (Number) | |
|---|---|---|
| Achieving Effective SBP Control | Achieving Effective DBP Control | |
| Nifedipine | 63.40 | 76.98 |
| Valsartan/Amlodipine | 82.40 | 92.88 |
Primary outcome (NCT02168309)
Timeframe: 24 hours
| Intervention | hours (Mean) |
|---|---|
| Labetalol | 37.6 |
| Nifedipine | 38.2 |
Secondary outcome (NCT02168309)
Timeframe: 0-10 days
| Intervention | days (Mean) |
|---|---|
| Labetalol | 4.0 |
| Nifedipine | 4.3 |
Carotid-femoral pulse wave velocity (PWV), a measure of arterial stiffness, is determined from the time taken for the arterial pulse to propagate from the carotid to the femoral artery. Baseline was defined as the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6
| Intervention | Meter per second (Mean) | ||
|---|---|---|---|
| Baseline | Change at Week 3 | Change at Week 6 | |
| Nifedipine | 7.94 | -0.21 | -0.38 |
| Placebo | 7.74 | -0.21 | 0.29 |
| Sitaxsentan | 7.97 | -0.19 | -0.41 |
Mean urine total protein assessment included 24-hour urine collections to assess total protein excretion per 24 hours. Baseline was derived from an average of Week 0 (pre-dose) 24-hour urine collections prior to each treatment period. Week 6 was derived from an average of Week 6 24-hour urine collections for each treatment period. (NCT00810732)
Timeframe: Baseline, Week 6
| Intervention | Grams per 24 hours (Mean) | |
|---|---|---|
| Baseline | Change at week 6 | |
| Nifedipine | 1.95 | 0.01 |
| Placebo | 2.07 | -0.06 |
| Sitaxsentan | 2.07 | -0.62 |
The 24-hour ambulatory BP monitoring was performed by using a BP cuff which was attached to the participant's arm, using the same arm throughout the study, with a small monitor that comfortably sits in the pocket of participant. Mean values over 24-hour measurements at each measurement period were calculated. The change in total 24-hour ambulatory monitoring of systemic arterial BP, SBP and DBP at Week 3 and 6 relative to baseline were reported. Baseline was as an average of the pre-dose measurement for the measure collected at Week 0 of each treatment period. Week 3 and Week 6 was an average of measurement for the measure collected at Week 3 and 6 of each treatment period. (NCT00810732)
Timeframe: Baseline, Week 3 and 6
| Intervention | Millimeter of Mercury (mmHg) (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean Systemic Arterial BP: Baseline | Mean Systemic Arterial BP: Change at Week 3 | Mean Systemic Arterial BP: Change at Week 6 | Mean Systemic Arterial SBP :Baseline | Mean Systemic Arterial SBP: Change at Week 3 | Mean Systemic Arterial SBP: Change at Week 6 | Mean Systemic Arterial DBP: Baseline | Mean Systemic Arterial DBP: Change at Week 3 | Mean Systemic Arterial DBP: Change at Week 6 | |
| Nifedipine | 93.78 | -2.95 | -3.54 | 125.12 | -4.20 | -4.47 | 78.27 | -2.09 | -2.86 |
| Placebo | 92.98 | -1.20 | -0.35 | 125.17 | -2.81 | -1.57 | 77.58 | -0.86 | -0.41 |
| Sitaxsentan | 92.94 | -4.59 | -3.74 | 124.03 | -4.88 | -3.99 | 77.56 | -4.85 | -3.60 |
This reports the change in the least square mean from baseline to 12 months, adjusted for age (NCT00605072)
Timeframe: Baseline-12 months
| Intervention | cm/sec (Least Squares Mean) |
|---|---|
| ACEI (Lisinopril) | -0.3 |
| ARB (Candesartan) | -2.85 |
| HCTZ | 0.35 |
Blood pressure was measured as follows: the participant was in the sitting position, rested for 5 minutes, no caffeine or smoking 2 hours prior to measurement, using appropriate cuff size (covering 60% of upper arm length and 80% of arm circumference), correct cuff placement (1-2 inches above brachial pulse on bare arm), and the bell of the stethoscope. The systolic blood pressure was defined as the pressure corresponding to the first korotkoff sounds (K1) and the diastolic as the pressure corresponding to the last korotkoff sound (K5). Blood pressure was measured in both arms and recorded (NCT00605072)
Timeframe: Baseline-12 months
| Intervention | mm Hg (Least Squares Mean) |
|---|---|
| ACEI (Lisinopril) | 28 |
| ARB (Candesartan) | 27 |
| HCTZ | 21 |
This test consists of series of digits of increasing length, some of which are recited as presented, and some of which are to be recited in reversed order. The forward digit span score ranges from 0 (ie cannot repeat two digits) to 8 ( participant can repeat up to 8 digits) (NCT00605072)
Timeframe: Baseline-12 months
| Intervention | number of digits repeated (Least Squares Mean) |
|---|---|
| ACEI (Lisinopril) | -0.3 |
| ARB (Candesartan) | 0.02 |
| HCTZ | -0.04 |
This is a 12-item list learning test in which individuals are presented three learning and recall trials followed by a delayed recall and 24 item recognition test. The HVLT-R has been identified as an ideal memory measure for elderly patients, and appropriate reliability and validity have been shown in older individuals. The test score is the number of correct answers in the delayed recall ( score range 0-12) (NCT00605072)
Timeframe: Baseline-12 months
| Intervention | number words remembered (Least Squares Mean) |
|---|---|
| ACEI (Lisinopril) | -1 |
| ARB (Candesartan) | -2 |
| HCTZ | -3 |
This test requires the connection of sequentially numbered circles (A), and the connection of circles marked by numbers and letters in alternating sequence (B). This test is considered a benchmark of executive function. The test score is the time required to complete the task in seconds. (NCT00605072)
Timeframe: Baseline-12 months
| Intervention | seconds (Least Squares Mean) |
|---|---|
| ACEI (Lisinopril) | -14 |
| ARB (Candesartan) | 17 |
| HCTZ | 4 |
(NCT00893984)
Timeframe: 30 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Nebivolol | 0 |
(NCT00893984)
Timeframe: 30 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Nebivolol | 0 |
Mild symptoms include weight gain, edema, and headaches (NCT00893984)
Timeframe: 30 Days
| Intervention | participants (Number) |
|---|---|
| Nebivolol | 1 |
(NCT00893984)
Timeframe: 30 Days
| Intervention | Participants (Count of Participants) |
|---|---|
| Nebivolol | 0 |
(NCT01062763)
Timeframe: 4 months
| Intervention | participants (Number) |
|---|---|
| Addition of Spironolactone | 4 |
| Placebo | 0 |
Change of diastolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months
| Intervention | mm Hg (Mean) |
|---|---|
| Addition of Spironolactone | -3.9 |
| Placebo | -0.3 |
Change of systolic blood pressure from baseline to study end at four months. (NCT01062763)
Timeframe: 4 months
| Intervention | mm Hg (Mean) |
|---|---|
| Addition of Spironolactone | -9.6 |
| Placebo | -0.7 |
Survey to assess Frequency of side effects of nifedipine including peripheral edema (most common side effect, dose related), flushing, headache, dizziness, fatigue, constipation, nausea, and muscle cramps. (NCT03595982)
Timeframe: up to 24 hours
| Intervention | events (Number) |
|---|---|
| Procardia XL 30 mg | 1 |
| Procardia XL 60 mg | 2 |
Blood pressure reading (NCT03595982)
Timeframe: up to 24 hours
| Intervention | mmHg (Mean) | |
|---|---|---|
| Systolic | Diastolic | |
| Procardia XL 30 mg | 155 | 92 |
| Procardia XL 60 mg | 146 | 84 |
215 reviews available for nifedipine and Blood Pressure, High
| Article | Year |
|---|---|
Comparative peripheral edema for dihydropyridines calcium channel blockers treatment: A systematic review and network meta-analysis.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Edema; Humans; Hypertension; Ne | 2022 |
Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis.
Topics: Amlodipine; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; P | 2022 |
Different dosage regimens of nifedipine, labetalol, and hydralazine for the treatment of severe hypertension during pregnancy: a network meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Hypertension, Pr | 2022 |
Pharmacokinetics of the most commonly used antihypertensive drugs throughout pregnancy methyldopa, labetalol, and nifedipine: a systematic review.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Hypertension, Pregnancy-Induced; Labetalol; M | 2022 |
Hypertensive Crisis in Pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hydralazine; Hypertension; Labetalol; Nifedipine; Pregnancy | 2022 |
Synthesis of Dihydropyrimidines: Isosteres of Nifedipine and Evaluation of Their Calcium Channel Blocking Efficiency.
Topics: Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Humans; Hypert | 2023 |
Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydralazine; Hypertension; Infant | 2023 |
Comparative efficacy and safety of oral antihypertensive agents in pregnant women with chronic hypertension: a network metaanalysis.
Topics: Abruptio Placentae; Amlodipine; Antihypertensive Agents; Atenolol; Cesarean Section; Chronic Disease | 2020 |
Focused Update on Pharmacologic Management of Hypertensive Emergencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Brain Ischemia; Emergencies; Enalapri | 2018 |
Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Female; Headache; Humans; Hydralazine; Hy | 2018 |
Hypertension and Pregnancy: Management and Future Risks.
Topics: Antihypertensive Agents; Aspirin; Cardiovascular Diseases; Chronic Disease; Diuretics; Female; Human | 2019 |
Calcium channel blockers and risk of breast cancer: a meta-analysis of 17 observational studies.
Topics: Adult; Aged; Antihypertensive Agents; Breast Neoplasms; Calcium Channel Blockers; Case-Control Studi | 2014 |
Hypertensive emergencies in pregnancy.
Topics: Antihypertensive Agents; Eclampsia; Emergencies; Female; Humans; Hydralazine; Hypertension; Hyperten | 2014 |
Oral nifedipine versus intravenous labetalol for the treatment of severe hypertension in pregnancy.
Topics: Administration, Oral; Antihypertensive Agents; Female; Humans; Hypertension; Infusions, Intravenous; | 2015 |
Hypertensive Emergencies in Pregnancy.
Topics: Antihypertensive Agents; Cesarean Section; Chronic Disease; Congenital Abnormalities; Emergencies; E | 2016 |
The ACTION study: nifedipine in patients with symptomatic stable angina and hypertension.
Topics: Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Comorbidity; Cor | 2008 |
[Hypertensive crisis].
Topics: Aged; Calcium Channel Blockers; Diagnosis, Differential; Electrocardiography; Emergencies; Emergency | 2009 |
Long-acting nifedipine in the management of the hypertensive patient.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Delayed | 2008 |
Review of nifedipine GITS in the treatment of high risk patients with coronary artery disease and hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Coronary | 2009 |
[Calcium antagonists: current and future applications based on new evidence. Calcium antagonists and diabetes].
Topics: Antioxidants; Calcium Channel Blockers; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Reti | 2010 |
Nifedipine and telmisartan for the treatment of hypertension: the TALENT study.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium | 2011 |
Long-acting dihydropyridine calcium-channel blockers and sympathetic nervous system activity in hypertension: a literature review comparing amlodipine and nifedipine GITS.
Topics: Amlodipine; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Nifedipine; Sympathetic Ne | 2012 |
[Clinical efficacy and perinatal outcome of nifedipine for severe preeclampsia: meta-analysis].
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; Hypertension; Infant, Newborn; | 2012 |
Role of calcium channel blockers in the future, in view of the INSIGHT Study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiova | 2002 |
Clinical use of nifedipine GITS in the treatment of hypertension: an overview.
Topics: Delayed-Action Preparations; Humans; Hypertension; Nifedipine | 2003 |
Clinical trial experience around the globe: focus on calcium-channel blockers.
Topics: Amiloride; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Clinical Trials as To | 2003 |
Current treatment of patients with hypertension: therapeutic implications of INSIGHT.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; | 2003 |
Safety of short-acting nifedipine in children with severe hypertension.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Child; Clinical Trials as Topic; Humans; Hyperten | 2003 |
[Medication of the month. Adalat Oros 60 mg].
Topics: Clinical Trials as Topic; Delayed-Action Preparations; Humans; Hypertension; Nifedipine; Vasodilator | 2004 |
Combined antihypertensive and lipid-lowering treatment.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Arteriosclerosis; Cardiovascular Diseases; Comorb | 2004 |
New advances in the field of calcium channel antagonists: cardiovascular effects and structure-activity relationships.
Topics: Angina Pectoris; Animals; Calcium Channel Blockers; Calcium Channels; Cardiovascular System; Diltiaz | 2003 |
[Visiting high altitudes--healthy persons and patients with risk diseases].
Topics: Acclimatization; Acetazolamide; Acute Disease; Altitude; Altitude Sickness; Anti-Inflammatory Agents | 2004 |
The role of existing and newer calcium channel blockers in the treatment of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nit | 2004 |
Use of nifedipine in the treatment of hypertension.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; N | 2005 |
[Treatment of hypertensive patients with impaired glucose tolerance (IGT)].
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2005 |
Mechanism of tissue-selective drug action in the cardiovascular system.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Binding Sites; Calcium Channels; Cardiovascular System; Chemist | 2005 |
Barnidipine: a new calcium channel blocker for hypertension treatment.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Nifedipine | 2005 |
[Ischemic heart disease combined with hypertension: peculiarities of course and selection of therapy].
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive | 2005 |
The role of the new beta-blockers in treating cardiovascular disease.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Atenolol; Benzopyrans | 2005 |
Modified-release nifedipine: a review of the use of modified-release formulations in the treatment of hypertension and angina pectoris.
Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Hum | 2006 |
[Indications for calcium channel antagonist therapy according to the latest large clinical trials].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Cli | 2005 |
Pathophysiology and medical management of systemic hypertension in preeclampsia.
Topics: Adrenergic beta-Antagonists; Aspirin; Calcium; Calcium Channel Blockers; Cerebral Hemorrhage; Female | 2006 |
A review of calcium channel antagonists in the treatment of pediatric hypertension.
Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipi | 2006 |
[PICA study--hypertension and asymptomatic cerebral infarction].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarcti | 2006 |
Nifedipine Gastrointestinal Therapeutic System (GITS) in the treatment of coronary heart disease and hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Cost Savings; D | 2007 |
[STONE study and INSIGHT study: efficacy of nifedipine in the prevention of cardiovascular disease in hypertensive patients].
Topics: Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Nifedipine; Randomized Cont | 2006 |
[NICE-Combi study: effect of nifedipine in combination with an angiotensin II receptor blocker on BP control and renal protection].
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Doubl | 2006 |
[Effect of calcium channel blocker in combination with an angiotensin II receptor blocker in Japanese patients with hypertension].
Topics: Angiotensin Receptor Antagonists; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Hyper | 2006 |
[J-MIND study: effect of nifedipine on renal function in Japanese hypertensive patients with diabetes mellitus].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabet | 2006 |
[JMIC-B study and its sub-analyses: effect of nifedipine in Japanese hypertensive patients with coronary artery disease].
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronary Disease; Humans; Hyperte | 2006 |
Role of oxidative stress in the development of vascular injury and its therapeutic intervention by nifedipine.
Topics: Antioxidants; Apoptosis; Atherosclerosis; Calcium Channels; Cardiovascular Diseases; Cytokines; Diab | 2008 |
Understanding the calcium channel blockers.
Topics: Action Potentials; Angina Pectoris; Animals; Arrhythmias, Cardiac; Arteriosclerosis; Calcium; Calciu | 1984 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; | 1984 |
From beta blockers to Ca2+ blockers in hypertension: a review.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Coronary Circulation; Drug Therapy, Combinati | 1982 |
Clinical value of calcium antagonists in treatment of cardiovascular disorders.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calciu | 1983 |
Hypertension--drug management.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Captopril; Diaz | 1982 |
Treatment of vasospastic angina.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Anemia; Angina Pectoris, Variant; | 1983 |
Clinical applications of slow channel blocking compounds.
Topics: Adrenergic beta-Antagonists; Animals; Arrhythmias, Cardiac; Blood Platelets; Blood Vessels; Calcium | 1983 |
Calcium influx blockers in the treatment of essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aging; Animals; Drug Therapy, Combination; Forearm; Humans | 1984 |
Present concepts and perspectives of antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Therapy, Combi | 1982 |
Comparative pharmacology of calcium antagonists: nifedipine, verapamil and diltiazem.
Topics: Angina Pectoris; Angina Pectoris, Variant; Animals; Arrhythmias, Cardiac; Benzazepines; Calcium; Car | 1980 |
Mechanism of action of calcium-channel-blocking agents.
Topics: Action Potentials; Angina Pectoris; Arrhythmias, Cardiac; Blood Vessels; Calcium; Calcium Channel Bl | 1982 |
Calcium channel blocking drugs.
Topics: Anesthesia; Angina Pectoris; Animals; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophi | 1983 |
Hypertension: calcium-blocking agents in treatment.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Hypertens | 1984 |
Slow channel blockers.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Cons | 1983 |
[Calcium antagonists in cardiology].
Topics: Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Coronary Disease; Dilt | 1983 |
Calcium antagonists. Clinical use in the treatment of systemic hypertension.
Topics: Angina Pectoris; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1983 |
[Calcium antagonists in the therapy of hypertension].
Topics: Biological Transport; Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Hyperten | 1983 |
Calcium, drug action and hypertension.
Topics: Animals; Arteries; Calcium; Chelating Agents; Humans; Hydralazine; Hypertension; Lanthanum; Muscle C | 1983 |
Possible treatment of pre-eclampsia with calcium channel blocking agents.
Topics: Calcium Channel Blockers; Eclampsia; Female; Fetus; Humans; Hypertension; Nifedipine; Placenta; Pre- | 1983 |
Treatment of hypertension with calcium channel blockers: European data.
Topics: Age Factors; Blood Pressure; Calcium Channel Blockers; Coronary Disease; Diltiazem; Europe; Humans; | 1984 |
Calcium entry blockers as vasodilators in man.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Vascular Res | 1984 |
Hypertensive crisis.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1984 |
Microcirculatory actions and uses of naturally-occurring (magnesium) and novel synthetic calcium channel blockers.
Topics: Anesthesia; Animals; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Cell Membrane Pe | 1984 |
New antiarrhythmic drugs.
Topics: Amiodarone; Angina Pectoris; Anti-Arrhythmia Agents; Blood Circulation; Bradycardia; Diltiazem; Half | 1983 |
Calcium antagonists in the treatment of hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Diltiazem; Heart Rate; Humans; Hypertension; Nife | 1982 |
[New therapeutic approaches to arterial hypertension].
Topics: Angiotensin II; Benzothiadiazines; Calcium; Calcium Channel Blockers; Captopril; Diuretics; Drug The | 1982 |
Calcium entry blockers: uses and implications for anesthesiologists.
Topics: Anesthesia, General; Animals; Arrhythmias, Cardiac; Biotransformation; Calcium Channel Blockers; Cor | 1982 |
[Indications for use of calcium antagonists].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium; Cardiotonic Agents; Coronary Disease | 1980 |
Calcium blockade as a therapeutic principle in arterial hypertension. Clinical aspects and experimental studies on isolated vessels from spontaneously hypertensive rats and normotensive man.
Topics: Animals; Biological Transport; Blood Pressure; Blood Vessels; Calcium; Calcium Channel Blockers; Fem | 1981 |
Hypertension treatment and prevention of new atherosclerotic plaque formation.
Topics: Animals; Arteriosclerosis; Calcium Channel Blockers; Coronary Angiography; Coronary Vessels; Endothe | 1994 |
Future prospects for calcium antagonists.
Topics: Animals; Calcium Channel Blockers; Coronary Vessels; Forecasting; Hypertension; Kidney; Muscle, Smoo | 1994 |
Intracranial pheochromocytoma--a case of noradrenaline-secreting glomus jugulare tumor.
Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Diagnosis, Differential; Diltiazem; Embolizatio | 1995 |
Etiology, pathophysiology, and treatment of left ventricular hypertrophy: focus on severe hypertension.
Topics: Administration, Oral; Blood Pressure; Delayed-Action Preparations; Drug Delivery Systems; Female; Hu | 1993 |
Use of nifedipine in the hypertensive diseases of pregnancy.
Topics: Female; Humans; Hydralazine; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy; Pregnancy Complicat | 1994 |
Trough:peak ratio of the blood pressure response to dihydropyridine calcium antagonists. Italian Nifedipine GITS Study Group.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dihydropyridines; H | 1994 |
Nilvadipine. A review of its pharmacodynamic and pharmacokinetic properties, therapeutic use in hypertension and potential in cerebrovascular disease and angina.
Topics: Aging; Angina Pectoris; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular | 1995 |
Poisoning with anti-hypertensive drugs: calcium antagonists.
Topics: Age Factors; Antihypertensive Agents; Calcium; Diltiazem; Drug Overdose; Humans; Hypertension; Nifed | 1995 |
Nilvadipine: profile of a new calcium antagonist. An overview.
Topics: Antihypertensive Agents; Biological Availability; Blood Pressure; Calcium Channel Blockers; Cerebrov | 1994 |
[Pharmacology and clinical use of a fixed combination of nifedipine and slow release atenolol (Niften) in the treatment of arterial hypertension and angina pectoris].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Delayed-Action Pre | 1993 |
Therapeutic coverage: reducing the risks of partial compliance.
Topics: Drug Administration Schedule; Enalapril; Humans; Hypertension; Nifedipine; Patient Compliance | 1994 |
[Hypertensive encephalopathy].
Topics: Animals; Brain Diseases; Diagnosis, Differential; Humans; Hypertension; Nifedipine; Nitroglycerin; P | 1993 |
Nifedipine and its indications in obstetrics and gynecology.
Topics: Animals; Female; Fetus; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Cardio | 1994 |
[Advances in cardiovascular diseases in China].
Topics: Catheter Ablation; Humans; Hypertension; Myocardial Infarction; Nifedipine; Urokinase-Type Plasminog | 1993 |
Pharmacology of the dihydropyridine calcium antagonists: relationship between lipophilicity and pharmacodynamic responses.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Humans; | 1993 |
Oral antihypertensives for hypertensive urgencies.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Captopril; Clonidine; Female; Humans; | 1994 |
Unique pharmacologic properties of amlodipine.
Topics: Amlodipine; Animals; Aorta; Calcium Channel Blockers; Delayed-Action Preparations; Dogs; Hypertensio | 1994 |
Similarities and differences between calcium antagonists: pharmacological aspects.
Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Hum | 1993 |
Nifedipine gastrointestinal therapeutic system (GITS). A review of its pharmacodynamic and pharmacokinetic properties and therapeutic efficacy in hypertension and angina pectoris.
Topics: Administration, Oral; Angina Pectoris; Drug Delivery Systems; Humans; Hypertension; Nifedipine; Phar | 1995 |
[Calcium antagonists--much noise about nothing?].
Topics: Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertension; Myocardial Infarct | 1995 |
Vascular selective calcium entry blockers in the treatment of cardiovascular disorders: focus on felodipine.
Topics: Amlodipine; Calcium Channel Blockers; Coronary Disease; Felodipine; Heart Failure; Hemodynamics; Hum | 1995 |
Short acting dihydropyridine (vasodilating) calcium channel blockers for hypertension: is there a risk?
Topics: Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Humans; | 1996 |
[Emergency situations in hypertension].
Topics: Administration, Sublingual; Antihypertensive Agents; Captopril; Crisis Intervention; Emergencies; Fe | 1996 |
[Selected passages from the clinical trials of Cordaflex].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hungary; Hypert | 1996 |
1995: the year of the calcium antagonist controversy.
Topics: Calcium Channel Blockers; Humans; Hypertension; Myocardial Infarction; Myocardial Ischemia; Nifedipi | 1996 |
The nifedipine gastrointestinal therapeutic system (GITS). Evaluation of pharmaceutical, pharmacokinetic and pharmacological properties.
Topics: Animals; Calcium Channel Blockers; Delayed-Action Preparations; Digestive System; Humans; Hypertensi | 1996 |
The value of nifedipine in the treatment of hypertension, coronary heart disease and myocardial infarction (post-infarction therapy).
Topics: Adult; Aged; Calcium Channel Blockers; Coronary Disease; Female; Germany; Humans; Hypertension; Male | 1996 |
Critical appraisal of recent studies on nifedipine and other calcium channel blockers in coronary artery disease and hypertension.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hypertension; Meta-Ana | 1996 |
A 1996 update on antihypertensive agents.
Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Carbazoles; Car | 1996 |
Searching for signals: mortality and cardiovascular events in published randomized control trials of nifedipine in ischemic heart disease and hypertension.
Topics: Humans; Hypertension; Myocardial Ischemia; Nifedipine; Randomized Controlled Trials as Topic; Vasodi | 1996 |
Antihypertensive therapy debate: contribution from the Shanghai Trial Of Nifedipine in the Elderly (STONE).
Topics: Age Factors; Aged; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Humans; | 1996 |
Benefit versus risk of calcium antagonists in hypertensive patients with concomitant risk factors.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Risk Factors | 1996 |
Calcium channel blockers for hypertension: dissecting the evidence for adverse effects.
Topics: Calcium Channel Blockers; Catecholamines; Cerebrovascular Disorders; Drug Evaluation; Gastrointestin | 1997 |
Safety of nifedipine in patients with hypertension: a meta-analysis.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Cross-Over Studies; Diuretics; D | 1997 |
[Calcium channel blocker for therapy of patients with hypertension].
Topics: Benzimidazoles; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Humans; Hypertension; | 1997 |
Diversity of calcium antagonists.
Topics: Angina Pectoris; Arteriosclerosis; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hype | 1997 |
Structure and function of small arteries of essential hypertensive patients following chronic treatment with once-a-day nifedipine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arterioles; Atenolol; Blood Pressure; Calcium Channel Bloc | 1997 |
[Exercise hemodynamic in hypertension associated with coronary microangiopathy, coronary heart disease and without ischemic syndrome effect of nifedipine].
Topics: Coronary Disease; Echocardiography; Ergometry; Female; Heart Function Tests; Hemodynamics; Humans; H | 1997 |
[Controversy about using calcium antagonists for treatment of coronary disease and hypertension].
Topics: Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Topic; Coronary Disease; Hum | 1997 |
Use of calcium channel blockers in hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Stud | 1998 |
Calcium channel antagonists: morbidity and mortality--what's the evidence?
Topics: Administration, Sublingual; Aged; Calcium Channel Blockers; Gastrointestinal Hemorrhage; Humans; Hyp | 1998 |
Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients.
Topics: Amlodipine; Calcium Channel Blockers; Cause of Death; Cerebrovascular Disorders; Clinical Trials as | 1998 |
Pharmacological profile of barnidipine: a single optical isomer dihydropyridine calcium antagonist.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Dogs; Guinea Pigs; Hypertension; Nifedipine; Ra | 1998 |
[Atenolol/nifedipine combination: efficacy and tolerability of low dose synergistic bitherapy in the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Dose-Respo | 1998 |
Hypotension and coronary events on nifedipine: reassessing nifedipine safety.
Topics: Angina, Unstable; Calcium Channel Blockers; Contraindications; Drug Evaluation; France; Humans; Hype | 1998 |
Management of acute severe hypertension and encephalopathy.
Topics: Acute Disease; Antihypertensive Agents; Brain Diseases; Female; Humans; Hypertension; Nifedipine; Ni | 1999 |
[Edema and skin ulcers of the lower limbs as a collateral effect of nifedipine. A clinical case report].
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Chronic Disease; | 1999 |
Intramural hematoma of the thoracic aorta in octogenarians: is non operation justified?
Topics: Aged; Aged, 80 and over; Analgesics; Aorta, Thoracic; Aortic Diseases; Aortography; Arteriosclerosis | 1999 |
Diagnosis and management of hypertensive emergencies.
Topics: Adrenergic alpha-Agonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aortic | 1999 |
Does combination therapy with a calcium channel blocker and an ACE inhibitor have additive effects on blood pressure reduction?
Topics: Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Ch | 2000 |
The diagnosis and management of hypertensive crises.
Topics: Antihypertensive Agents; Aortic Aneurysm; Aortic Dissection; Clonidine; Diazoxide; Enalaprilat; Fema | 2000 |
Circadian heart rate response to chronotherapy versus conventional therapy in patients with hypertension and myocardial ischemia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amlodipine; Atenolol; Blood Pressure; C | 2000 |
Experimental studies on myocardial stretch and ventricular arrhythmia in hypertrophied and non-hypertrophied hearts.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Death, Sudden, | 2000 |
Barnidipine, a long-acting slow onset calcium antagonist.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dogs; Guinea Pigs; Humans; Hypertension; Nifedipi | 2000 |
Interaction profile and tolerability of barnidipine.
Topics: Aged; Calcium Channel Blockers; Drug Interactions; Humans; Hypertension; Middle Aged; Nifedipine | 2000 |
Barnidipine.
Topics: Aged; Animals; Area Under Curve; Biological Availability; Calcium Channel Blockers; Hemodynamics; Hu | 2001 |
Hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Emergencies; Humans; Hypertension; Nifedipine | 2001 |
Calcium channel blockers in the management of preterm labor and hypertension in pregnancy.
Topics: Breast Feeding; Calcium Channel Blockers; Female; Humans; Hypertension; Maternal-Fetal Exchange; Nif | 2001 |
The INSIGHT and NORDIL trials: Are calcium antagonists equivalent to established drug therapies for cardiovascular protection?
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Diuretics | 2001 |
Dangers, myths, controversy. Sublingual nifedipine for hypertensive crisis.
Topics: Administration, Sublingual; Calcium Channel Blockers; Emergencies; Humans; Hypertension; Nifedipine | 2000 |
[Misleading advertisement of Adalat Oros].
Topics: Advertising; Calcium Channel Blockers; Data Interpretation, Statistical; Deception; Diuretics; Drug | 2001 |
The patient with hypertension.
Topics: Anesthesia, Dental; Calcium Channel Blockers; Coronary Disease; Dental Care for Chronically Ill; Eme | 2001 |
[Are newer antihypertensive agents better than the older ones? Results of trials (CAPPP, STOP-2, NORDIL, INSIGHT and ALLHAT) with newer antihypertensive agents].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Bloc | 2001 |
Long-term protection in at-risk hypertensive patients--a role for nifedipine GITS?
Topics: Amiloride; Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Drug Comb | 2002 |
Angiotensin converting enzyme inhibition and dihydropyridine calcium channel blockade in the treatment of left ventricular hypertrophy in arterial hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Atenolol; Calcium Channe | 2002 |
[Calcium antagonists in cardiology].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Calcium; Coronary Disease; Human | 1978 |
Clinical aspects of Ca-blocking agents.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Cricetinae; Humans; Hyper | 1978 |
Quality of life in the treatment of hypertension. The effect of calcium antagonists.
Topics: Calcium Channel Blockers; Captopril; Humans; Hypertension; Male; Nifedipine; Propranolol; Quality of | 1992 |
[Nifedipine in gynecology and obstetrics].
Topics: Amenorrhea; Antihypertensive Agents; Female; Fetus; Humans; Hypertension; Nifedipine; Obstetric Labo | 1992 |
Clinical pharmacokinetics of amlodipine.
Topics: Absorption; Amlodipine; Angina Pectoris; Biological Availability; Calcium Channel Blockers; Drug Int | 1992 |
Sustained release nifedipine formulations. An appraisal of their current uses and prospective roles in the treatment of hypertension, ischaemic heart disease and peripheral vascular disorders.
Topics: Coronary Disease; Delayed-Action Preparations; Drug Combinations; Drug Design; Humans; Hypertension; | 1991 |
Doppler flow velocimetry in hypertension in pregnancy.
Topics: Female; Fetus; Hemodynamics; Humans; Hypertension; Labetalol; Mass Screening; Nifedipine; Placenta; | 1991 |
[Amlodipine].
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1991 |
[Amlodipin (Norvasc). A new calcium antagonist with long half-life].
Topics: Amlodipine; Angina Pectoris; Calcium Channel Blockers; Half-Life; Humans; Hypertension; Nifedipine | 1991 |
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Human | 1991 |
Amlodipine: an effective once-daily antihypertensive agent.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Administration S | 1991 |
The clinical consequences of the absorption, distribution, metabolism and excretion of amlodipine.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1991 |
Amlodipine in the treatment of hypertension.
Topics: Amlodipine; Blood Pressure Determination; Calcium Channel Blockers; Clinical Trials as Topic; Dose-R | 1991 |
Influence of nifedipine on experimental arteriosclerosis.
Topics: Animals; Arteriosclerosis; Hypertension; Nifedipine; Rabbits; Rats | 1990 |
Use of nifedipine in hypertension and Raynaud's phenomenon.
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Raynaud Disease | 1990 |
Nifedipine interactions in hypertensive patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Humans; Hypertension; Nifedipine | 1990 |
[Effect of moderate salt restriction on the antihypertensive action of nifedipine: a double blind study].
Topics: Clinical Trials as Topic; Diet, Sodium-Restricted; Double-Blind Method; Drug Evaluation; Humans; Hyp | 1990 |
Use of crossover trials to obtain antihypertensive dose-response curves and to study combination therapy during the development of benazepril.
Topics: Antihypertensive Agents; Benzazepines; Blood Pressure; Dose-Response Relationship, Drug; Drug Admini | 1990 |
Review of the cardiovascular adversity of the calcium antagonist beta-blocker combination: implications for antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Drug Ther | 1985 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Calcium antagonists in the treatment of hypertension.
Topics: Biological Transport, Active; Calcium; Calcium Channel Blockers; Captopril; Diltiazem; Diuretics; Dr | 1985 |
Amlodipine in hypertension: an overview of the clinical dossier.
Topics: Amlodipine; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1988 |
Nifedipine and hypertension: roles of vasodilation and sodium balance.
Topics: Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Humans; Hypertension; Muscle, S | 1989 |
Calcium channel blockers. Potential medical benefits and side effects.
Topics: Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise; Humans; Hypertension; Nifedipine; Uni | 1989 |
An atenolol/nifedipine tablet for hypertension--useful or not?
Topics: Atenolol; Drug Combinations; Humans; Hypertension; Nifedipine | 1989 |
[Primary hyperaldosteronism caused by unilateral macronodular hyperplasia].
Topics: Adrenal Gland Diseases; Adrenal Glands; Adult; Clonidine; Follow-Up Studies; Humans; Hyperaldosteron | 1989 |
Nifedipine and systemic hypertension.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diuretics; Dr | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hyperte | 1989 |
Calcium channel blockade in heart failure.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Heart; Heart Failure; Hemodyna | 1989 |
[Calcium antagonists in the treatment of moderate arterial hypertension].
Topics: Calcium Channel Blockers; Heart; Hemodynamics; Humans; Hypertension; Nifedipine; Verapamil | 1989 |
Calcium-entry blocking agents in the treatment of systemic hypertension.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diuretics; Drug Ther | 1985 |
Selection of optimal drug therapy for the patient with angina pectoris.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Arrhythmias, Cardiac; Blood Pressure; Calcium Channel | 1985 |
Nifedipine in combination therapy for chronic hypertension. A review.
Topics: Adrenergic beta-Antagonists; Chronic Disease; Drug Therapy, Combination; Humans; Hypertension; Nifed | 1985 |
Antihypertensive drugs in pregnancy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Diazoxide; Diuretics; Female; Fetus; Humans; H | 1985 |
Antihypertensive therapy with calcium-channel blockers: comparison with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Tri | 1985 |
[Calcium antagonists in the treatment of arterial hypertension].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Diuretics | 1985 |
Combination therapy with beta-adrenoceptor blockers and calcium antagonists.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Verapamil | 1986 |
Clinical trials of verapamil: comparative studies of verapamil with beta-blockers and nifedipine.
Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Humans; Hypertension; Nifedipine; Verapamil | 1988 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension | 1985 |
Effects of calcium entry blockers on renin-angiotensin-aldosterone system, renal function and hemodynamics, salt and water excretion and body fluid composition.
Topics: Animals; Blood Pressure; Body Fluids; Calcium Channel Blockers; Diltiazem; Diuresis; Glomerular Filt | 1985 |
Pharmacokinetics of calcium channel blocking agents.
Topics: Administration, Oral; Angina Pectoris; Atrial Fibrillation; Biological Availability; Cardiomegaly; C | 1986 |
[Arterial hypertension in the newborn infant. Etiologies. Treatment].
Topics: Acebutolol; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Endoc | 1988 |
Nisoldipine. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of angina pectoris, hypertension and related cardiovascular disorders.
Topics: Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Nifedipine | 1988 |
[Calcium antagonists in arterial hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Drug Interactions; Heart Diseases; Hemodynamics; Humans; Hypert | 1988 |
The comparative effects of clonidine hydrochloride and nifedipine in the treatment of hypertensive crises.
Topics: Clonidine; Emergencies; Humans; Hypertension; Nifedipine | 1988 |
Geriatric hypertension: the growing use of calcium-channel blockers.
Topics: Aged; Calcium; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1988 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; | 1988 |
Calcium antagonists in the treatment of hypertension. An overview.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Verapamil | 1988 |
[Dynamic behavior of arterial pressure during exertion. Effects of treatment with 2 different calcium blockers: nifedipine and verapamil].
Topics: Adult; Blood Pressure; Exercise Test; Humans; Hypertension; Male; Middle Aged; Nifedipine; Physical | 1988 |
Treatment of severe hypertension and hypertensive crises with nifedipine.
Topics: Hemodynamics; Humans; Hypertension; Nifedipine | 1987 |
Differential effects of 1,4-dihydropyridine calcium channel blockers: therapeutic implications.
Topics: Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Hemod | 1987 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Prep | 1987 |
The role of calcium channel blockers in the treatment of hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiaz | 1986 |
Kinetics and dynamics of calcium entry antagonists in systemic hypertension.
Topics: Administration, Oral; Animals; Calcium Channel Blockers; Diltiazem; Half-Life; Hemodynamics; Humans; | 1986 |
[Does every 3d patient with essential hypertension have an undiagnosed sleep apnea syndrome?].
Topics: Adult; Blood Pressure; Combined Modality Therapy; Humans; Hypertension; Male; Middle Aged; Nifedipin | 1986 |
Advances in calcium blocker therapy.
Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B | 1986 |
Treatment of hypertensive urgencies and emergencies with nifedipine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Emergencies; Hemodynamics | 1986 |
Calcium channel blockers in systemic hypertension.
Topics: Animals; Calcium Channel Blockers; Delayed-Action Preparations; Diltiazem; Drug Interactions; Humans | 1986 |
Nifedipine in myocardial ischemia, systemic hypertension, and other cardiovascular disorders.
Topics: Angina Pectoris; Calcium Channel Blockers; Cardiovascular Diseases; Coronary Disease; Humans; Hypert | 1986 |
Sodium intake, high blood pressure, and calcium channel blockers.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Humans; Hypertension; Kidney; Nifedipine | 1987 |
The role of calcium entry blockers in hypertensive emergencies.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emergencies; Humans; H | 1987 |
Calcium antagonists in patients with cardiovascular disease. Current perspectives.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atrial Fibrillation; Atrial Flutter; Benzazepines; Cardio | 1985 |
Use of calcium antagonists in ventricular dysfunction.
Topics: Calcium Channel Blockers; Diltiazem; Heart Diseases; Heart Ventricles; Hemodynamics; Humans; Hyperte | 1985 |
Cerebral blood flow autoregulation and hypertension.
Topics: Aged; Animals; Antihypertensive Agents; Brain Diseases; Cerebrovascular Circulation; Chronic Disease | 1985 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron | 1985 |
Calcium channel blocking agents: physiologic basis of nursing intervention.
Topics: Angina Pectoris; Angina Pectoris, Variant; Atrioventricular Node; Calcium; Calcium Channel Blockers; | 1985 |
Hypertensive cardiovascular emergencies.
Topics: Antihypertensive Agents; Brain Diseases; Cerebrovascular Disorders; Clonidine; Coronary Disease; Dia | 1985 |
Calcium-channel blockers and systemic hypertension.
Topics: Acute Disease; Angina Pectoris; Animals; Calcium Channel Blockers; Chronic Disease; Diltiazem; Drug | 1985 |
Calcium antagonists in the treatment of hypertension: a critical overview.
Topics: Aldosterone; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiac Output; Catecholamines; Hear | 1985 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltia | 1985 |
917 trials available for nifedipine and Blood Pressure, High
| Article | Year |
|---|---|
Trial of Intrapartum Extended-Release Nifedipine to Prevent Severe Hypertension Among Pregnant Individuals With Preeclampsia With Severe Features.
Topics: Blood Pressure; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Pre-Eclampsia; Pregnancy | 2023 |
Effects of Nifedipine and Labetalol Combined with Magnesium Sulfate on Blood Pressure Control, Blood Coagulation Function, and Maternal and Infant Outcome in Patients with Pregnancy-Induced Hypertension.
Topics: Antihypertensive Agents; Blood Coagulation; Blood Pressure; Female; Humans; Hypertension; Hypertensi | 2022 |
Oral combined hydrochlorothiazide and lisinopril vs nifedipine for postpartum hypertension: a comparative-effectiveness pilot randomized controlled trial.
Topics: Antihypertensive Agents; Bayes Theorem; Blood Pressure; Double-Blind Method; Female; Humans; Hydroch | 2023 |
A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA).
Topics: Animals; Antihypertensive Agents; Female; Humans; Hypertension; Infant; Infant, Newborn; Labetalol; | 2023 |
A randomized controlled trial comparing the efficacy of nifedipine and enalapril in the postpartum period.
Topics: Antihypertensive Agents; Enalapril; Female; Humans; Hypertension; Nifedipine; Postpartum Period; Pre | 2023 |
Quantifying adherence to antihypertensive medication for chronic hypertension during pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Chromatography, High Pressure Liquid; | 2019 |
Methyldopa versus nifedipine or no medication for treatment of chronic hypertension during pregnancy: A multicenter randomized clinical trial.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Egypt; Female; Humans; Hypertension; Hypertens | 2019 |
Blood Pressure Variability and Progression of Clinical Alzheimer Disease.
Topics: Aged; Alzheimer Disease; Antihypertensive Agents; Blood Pressure Determination; Cognition Disorders; | 2019 |
Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug Therapy, | 2019 |
A comparative study for the effects of nifedipine GITS and amlodipine besylate administrated in daytime or at nighttime on recovery of blood pressure rhythm and arterial stiffness in the young and middle-aged subjects with non-dipper hypertension (NARRAS)
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; H | 2020 |
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; T | 2021 |
Comparison of ambulatory blood pressure-lowering effects of higher doses of different calcium antagonists in uncontrolled hypertension: the Calcium Antagonist Controlled-Release High-Dose Therapy in Uncontrolled Refractory Hypertensive Patients (CARILLON)
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bl | 2017 |
Celastrol synergizes with oral nifedipine to attenuate hypertension in preeclampsia: a randomized, placebo-controlled, and double blinded trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug | 2017 |
Impact of baseline blood pressure on the magnitude of blood pressure lowering by nifedipine gastrointestinal therapeutic system: refreshing the Wilder's principle.
Topics: Antihypertensive Agents; Blood Pressure; China; Dose-Response Relationship, Drug; Heart Rate; Humans | 2017 |
Longitudinal changes in vascular function parameters in pregnant women with chronic hypertension and association with adverse outcome: a cohort study.
Topics: Adult; Antihypertensive Agents; Birth Weight; Black People; Blood Pressure; Chronic Disease; Cohort | 2019 |
Comparative effectiveness of antihypertensive drugs prescribed in Ethiopian healthcare practice: A pilot prospective, randomized, open label study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood | 2018 |
A randomized multicenter study on ambulatory blood pressure and arterial stiffness in patients treated with valsartan/amlodipine or nifedipine GITS.
Topics: Adult; Amlodipine, Valsartan Drug Combination; Ankle Brachial Index; Blood Pressure; Blood Pressure | 2019 |
A randomized controlled trial on the blood pressure-lowering effect of amlodipine and nifedipine-GITS in sustained hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Case-Co | 2019 |
Blood Pressure Lowering With Nilvadipine in Patients With Mild-to-Moderate Alzheimer Disease Does Not Increase the Prevalence of Orthostatic Hypotension.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel | 2019 |
Effects of Nilvadipine on Cerebral Blood Flow in Patients With Alzheimer Disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Calcium Channel Blockers; Cerebrovascular Circulation; D | 2019 |
Effect of nifedipine versus telmisartan on prevention of atrial fibrillation recurrence in hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Atrial Fibrillation; Benzimidazoles; Benzoates; Blood Press | 2013 |
Acute changes in blood pressure in patients with neuroblastoma treated with ¹³¹I-metaiodobenzylguanidine (MIBG).
Topics: 3-Iodobenzylguanidine; Adolescent; Age Factors; Blood Pressure; Child; Child, Preschool; Female; Hum | 2013 |
Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparation | 2014 |
Valsartan/amlodipine compared to nifedipine GITS in patients with hypertension inadequately controlled by monotherapy.
Topics: Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Asian People; De | 2013 |
Feasibility of regression of hypertension using contemporary antihypertensive agents.
Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Blood Pressure D | 2013 |
The efficacy and safety of arotinolol combined with a different calcium channel blocker in the treatment of Chinese patients with essential hypertension: a one-year follow-up study.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Amlodipine; Anti | 2014 |
Randomized trial comparing the effects of a low-dose combination of nifedipine GITS and valsartan versus high-dose monotherapy on central hemodynamics in patients with inadequately controlled hypertension: FOCUS study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calci | 2014 |
Vitamin D and nifedipine in the treatment of Chinese patients with grades I-II essential hypertension: a randomized placebo-controlled trial.
Topics: Aged; Blood Pressure; C-Reactive Protein; China; Dietary Supplements; Double-Blind Method; Essential | 2014 |
Nifedipine plus candesartan combination increases blood pressure control regardless of race and improves the side effect profile: DISTINCT randomized trial results.
Topics: Administration, Oral; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Press | 2014 |
[Dynamics of the hemostasis parameters in patients with arterial hypertension in treatment with combined antihypertensive agents].
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Drug Administration Schedule; Drug Combinat | 2014 |
Long-term safety and efficacy of high-dose controlled-release nifedipine (80 mg per day) in Japanese patients with essential hypertension.
Topics: Aged; Asian People; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Double-Bl | 2015 |
Comparison of the effects of barnidipine+losartan compared with telmisartan+hydrochlorothiazide on several parameters of insulin sensitivity in patients with hypertension and type 2 diabetes mellitus.
Topics: Adipokines; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; | 2015 |
Barnidipine or Lercanidipine on Echocardiographic Parameters in Hypertensive, Type 2 Diabetics with Left Ventricular Hypertrophy: A Randomized Clinical Trial.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines | 2015 |
Combination therapy with nifedipine GITS 60 mg: subanalysis of a prospective, 12-week observational study (AdADOSE).
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Delayed-Action Prepara | 2016 |
[Treatment of Level 2 Hypertension by Diagnosis and Treatment Program of Integrative Medicine: a Multi-centre, Randomized Controlled Trial].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drugs, Chinese Herbal; Humans; Hypertension; | 2015 |
Perindopril and barnidipine alone or combined with simvastatin on hepatic steatosis and inflammatory parameters in hypertensive patients.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Hum | 2015 |
Importance of sustained and "tight" blood pressure control in patients with high cardiovascular risk.
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cardio | 2016 |
Prognostic importance of pretreatment and on-treatment blood pressure: Further analysis of the ACTION database and the effect of nifedipine gastrointestinal therapeutic system.
Topics: Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Cardio | 2016 |
Nifedipine GITS/Candesartan Combination Therapy Lowers Blood Pressure Across Different Baseline Systolic and Diastolic Blood Pressure Categories: DISTINCT Study Subanalyses.
Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Ch | 2016 |
Nifedipine Treatment for Hypertension is Associated with Enhanced Lipolytic Activity and Accelerated Clearance of Postprandial Lipemia.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hyperlipidemias; Hypertension; | 2016 |
Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study.
Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension; Middle Aged; Nifedipine; Prospective Stu | 2016 |
Barnidipine compared to lercanidipine in addition to losartan on endothelial damage and oxidative stress parameters in patients with hypertension and type 2 diabetes mellitus.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; | 2016 |
[Effect of Jingui Shenqi pill combined with nifedipine for the treatment of elderly hypertensive patients with spleen-kidney Yang deficiency syndrome].
Topics: Aged; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Humans; Hypertension; Kidney Disease | 2015 |
Blood pressure response to six-minute walk test in hypertensive subjects exposed to high altitude: effects of antihypertensive combination treatment.
Topics: Adult; Altitude; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Double-Blind Me | 2016 |
Blood pressure-lowering effects of nifedipine/candesartan combinations in high-risk individuals: subgroup analysis of the DISTINCT randomised trial.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blocker | 2017 |
Oral nifedipine vs. intravenous labetalol for treatment of pregnancy-induced severe pre-eclampsia.
Topics: Administration, Intravenous; Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; D | 2016 |
Fixed-dose combination of nifedipine gastrointestinal therapeutic system and candesartan cilexetil in patients with moderate-to-severe essential hypertension: an open-label, long-term safety and efficacy study.
Topics: Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Drug Therapy, Com | 2016 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Oral labetalol compared to oral nifedipine for postpartum hypertension: A randomized controlled trial.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; | 2017 |
Nifedipine versus carvedilol in the treatment of de novo arterial hypertension after liver transplantation: results of a controlled clinical trial.
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Carbazoles; Carvedilol; Drug Therapy, Combina | 2008 |
Chronotherapy with nifedipine GITS in hypertensive patients: improved efficacy and safety with bedtime dosing.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rh | 2008 |
Nifedipine improves endothelial function: role of endothelial progenitor cells.
Topics: Adult; Apoptosis; Blood Pressure; Calcium Channel Blockers; Cell Count; Cell Differentiation; Cell M | 2008 |
[The efficiency of combinations of Enalapril and long-acting Nifedipin and Moxonidine in patients with arterial hypertension and a metabolic syndrome].
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, | 2008 |
Sex differences in blood pressure response to antihypertensive therapy in Chinese patients with hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Asian People; Atenolol; Blood Pressure; Captopril; China; Dela | 2008 |
Influence of nifedipine coat-core and amlodipine on systemic arterial stiffness modulated by sympathetic and parasympathetic activity in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Arteries; Blood Pressure; Calcium Channel Blockers; Female; Heart; Heart Ra | 2009 |
[Comparative assessment of a calcium antagonist with controlled release of nifedipine and enalapril in arterial hypertension in subjects older than 60 years].
Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blocker | 2009 |
Reduction of morning blood pressure surge after treatment with nifedipine GITS at bedtime, but not upon awakening, in essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug-Related Side Ef | 2009 |
Potential protective effect of long-term therapy with Xuezhikang on left ventricular diastolic function in patients with essential hypertension.
Topics: Aged; Biological Products; Blood Flow Velocity; C-Reactive Protein; Calcium Channel Blockers; Case-C | 2009 |
Compiled report on clinical efficacy and safety of nifedipine retard 10/20/nifedipine CD 30, as a first-line/add-on therapy in patients of hypertension: ENHANS trial.
Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Drug Therapy, Combination; Female; Humans; Hypertens | 2009 |
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combin | 2009 |
Reverse remodeling and improved function by antihypertensive treatment in hypertensive patients with coronary artery disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Coronary Ar | 2010 |
Arterial wave reflection during antihypertensive therapy with barnidipine: a 6-month, open-label study using an integrated cardiovascular ultrasound approach in patients with newly diagnosed hypertension.
Topics: Aged; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Carotid Arteries; Echocardiogra | 2009 |
Preferential benefits of nifedipine GITS in systolic hypertension and in combination with RAS blockade: further analysis of the 'ACTION' database in patients with angina.
Topics: Aged; Angina Pectoris; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; B | 2011 |
Effectiveness of barnidipine 10 or 20 mg plus losartan 50-mg combination versus losartan 100-mg monotherapy in patients with essential hypertension not controlled by losartan 50-mg monotherapy: A 12-week, multicenter, randomized, open-label, parallel-grou
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relati | 2010 |
Plasma plasminogen activator inhibitor 1 (PAI-1) and P-selectin levels in urgent hypertension: effect of single dose captopril and nifedipine on fibrinolytic activity.
Topics: Adult; Antihypertensive Agents; Captopril; Female; Fibrinolysis; Humans; Hypertension; Male; Middle | 2010 |
Effect of antihypertensive treatment on circulating endothelial progenitor cells in patients with mild essential hypertension.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Endothelial Cells; Female; Humans; Hydroch | 2011 |
Blood pressure control by the nifedipine GITS-telmisartan combination in patients at high cardiovascular risk: the TALENT study.
Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Moni | 2011 |
Effects of barnidipine in comparison with hydrochlorothiazide on endothelial function, as assessed by flow mediated vasodilatation in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Brachial Artery; Calcium Channel Blockers; Endothelium, Vascul | 2011 |
Selective endothelin-A receptor antagonism reduces proteinuria, blood pressure, and arterial stiffness in chronic proteinuric kidney disease.
Topics: Adult; Antihypertensive Agents; Arteries; Blood Pressure; Cross-Over Studies; Double-Blind Method; D | 2011 |
Combination of angiotensin II receptor antagonist with calcium channel blocker or diuretic as antihypertensive therapy for patients with chronic kidney disease.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2011 |
A crossover comparison of urinary albumin excretion as a new surrogate marker for cardiovascular disease among 4 types of calcium channel blockers.
Topics: Aged; Aged, 80 and over; Albuminuria; Biomarkers; Calcium Channel Blockers; Cardiovascular Diseases; | 2013 |
Comparison of the efficacy of nifedipine and hydralazine in hypertensive crisis in pregnancy.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hydralazine; H | 2011 |
Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension.
Topics: Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Cell Movement; Endothelium, Vascu | 2012 |
Microalbuminuria and sRAGE in high-risk hypertensive patients treated with nifedipine/telmisartan combination treatment: a substudy of TALENT.
Topics: Adolescent; Adult; Aged; Albuminuria; Antihypertensive Agents; Benzimidazoles; Benzoates; Drug Combi | 2012 |
Improved blood pressure control with nifedipine GITS/valsartan combination versus high-dose valsartan monotherapy in mild-to-moderate hypertensive patients from Asia: results from the ADVISE study, a randomized trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Asian People; Blood Pressure; Comorbidity; Drug Co | 2012 |
Efficacy of domestic bisoprolol,enalapril and nifedipine retard in mild to moderate hypertension: a randomized double-blind multicenter clinical trial in China.
Topics: Bisoprolol; Blood Pressure; China; Double-Blind Method; Enalapril; Humans; Hypertension; Nifedipine | 2002 |
Oxidative stress and TGFbeta in kidney-transplanted patients with cyclosporin-induced hypertension. Effect of carvedilol and nifedipine.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocker | 2002 |
Efficacy and safety of nifedipine tablets for the acute treatment of severe hypertension in pregnancy.
Topics: Acute Disease; Blood Pressure; Capsules; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregna | 2002 |
[Coagulative and fibrinolytic changes in patients with essential hypertension and the effect of sustained-release nifedipine].
Topics: Adult; Aged; Aged, 80 and over; Blood Coagulation; Delayed-Action Preparations; Female; Fibrinolysis | 2002 |
Improvement of insulin sensitivity by a long-acting nifedipine preparation (nifedipine-CR) in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Area Under Curve; Blood Glucose; Calcium Channel Blockers; Delaye | 2002 |
Persistence of the antihypertensive efficacy of amlodipine and nifedipine GITS after two 'missed doses': a randomised, double-blind comparative trial in Asian patients.
Topics: Amlodipine; Antihypertensive Agents; Asia, Southeastern; Blood Pressure Monitoring, Ambulatory; Dose | 2002 |
Metabolic effects of combined antihypertensive treatment in patients with essential hypertension.
Topics: Antihypertensive Agents; Atenolol; Blood Glucose; Cholesterol; Double-Blind Method; Drug Administrat | 2002 |
Effect of calcium antagonist on cerebral blood flow and oxygen metabolism in patients with hypertension and chronic major cerebral artery occlusion: a positron emission tomography study.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Carotid Stenosis; Cerebrovascular Circulation; Femal | 2003 |
Differential effects of once-daily antihypertensive drugs on blood pressure, left ventricular mass and sympathetic activity: Nifedipine-GITS versus felodipine-ER versus enalapril.
Topics: Antihypertensive Agents; Biomarkers; Blood Pressure; Data Interpretation, Statistical; Enalapril; Fe | 2002 |
Effects of angiotensin converting enzyme inhibitor on renal function in patients of membranoproliferative glomerulonephritis with mild to moderate renal insufficiency.
Topics: Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Dose-Response Relationship, D | 2002 |
Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).
Topics: Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular D | 2003 |
Combination of lisinopril and nifedipine GITS increases blood pressure control compared with single drugs in essential hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Fem | 2003 |
Evaluation of the effect of the sublingually administered nifedipine and captopril via transcranial doppler ultrasonography during hypertensive crisis.
Topics: Administration, Sublingual; Analysis of Variance; Antihypertensive Agents; Blood Flow Velocity; Bloo | 2003 |
Regression of left ventricular hypertrophy after treatment of hypertension: comparison of directed M-echocardiography with magnetic resonance imaging in quantification of serial mass changes.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Echocardiography; Enalapril; Female; Humans | 2003 |
Restoration of nocturnal dip in blood pressure is associated with improvement in left ventricular ejection fraction. A 1-year clinical study comparing the effects of amlodipine and nifedipine retard on ambulatory blood pressure and left ventricular systol
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; C | 2003 |
The dilemma of immediate preoperative hypertension: to treat and operate, or to postpone surgery?
Topics: Administration, Intranasal; Aged; Aged, 80 and over; Antihypertensive Agents; Appointments and Sched | 2003 |
Effects of nifedipine on carotid and femoral arterial wall thickness in previously untreated hypertensive patients.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Carotid Arteries; Cholesterol; Echocardiography; Fe | 2003 |
Treatment of mild-to-moderate hypertension with calcium channel blockers: a multicentre comparison of once-daily nifedipine GITS with once-daily amlodipine.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Administration Schedule; Dru | 2003 |
Differential effects of lercanidipine and nifedipine GITS on plasma norepinephrine in chronic treatment of hypertension.
Topics: Adult; Aged; Calcium Channel Blockers; Dihydropyridines; Female; Hemodynamics; Humans; Hypertension; | 2003 |
Effects of protocol-driven care versus usual outpatient clinic care on survival rates in patients with type 2 diabetes.
Topics: Aged; Antihypertensive Agents; Blood Glucose; Cholesterol, HDL; Cholesterol, LDL; Clinical Protocols | 2003 |
Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ankle; Antihyperte | 2003 |
Effects of manidipine and nifedipine on blood pressure and renal function in patients with chronic renal failure: a multicenter randomized controlled trial.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Kid | 2003 |
Effects of calcium channel antagonists on left ventricular hypertrophy and diastolic function in patients with essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Dihydropyri | 2003 |
Pycnogenol, French maritime pine bark extract, improves endothelial function of hypertensive patients.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Angiotensin II; Blood Chemical Analysis; Blood Pressure; | 2004 |
Effects of the combination of low-dose nifedipine GITS 20 mg and losartan 50 mg in patients with mild to moderate hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination | 2004 |
[Assessment of the efficacy and tolerance of delayed-action nifedipine as the monotherapy or in combination with metoprolol in patients with arterial hypertension].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Preparatio | 2003 |
Comparison of nifedipine retard with angiotensin converting enzyme inhibitors in Japanese hypertensive patients with coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JMIC-B) randomized trial.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Asian People; Blood Pressure; Calcium Channel Blocke | 2004 |
Comparison of once-daily nifedipine controlled-release with twice-daily nifedipine retard in the treatment of essential hypertension.
Topics: Adult; Aged; Autonomic Nervous System; Blood Pressure; Delayed-Action Preparations; Female; Heart Ra | 2004 |
Effects of low-dose nifedipine GITS on sympathetic activity in young and older patients with hypertension.
Topics: Adult; Age Factors; Aged; Angiotensin II; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 2004 |
Large artery wall thickening and its determinants under antihypertensive treatment: the IMT-INSIGHT study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Carot | 2004 |
Comparison of the effects of a 7-day period of non-compliance on blood pressure control using three different antihypertensive agents.
Topics: Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Enalapril; H | 2004 |
Antihypertensive effects of long-acting calcium channel blockers on hemodialysis days--a randomized crossover trial between benidipine and nifedipine CR.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channe | 2004 |
Nifedipine retard was as effective as angiotensin converting enzyme inhibitors in preventing cardiac events in high-risk hypertensive patients with diabetes and coronary artery disease: the Japan Multicenter Investigation for Cardiovascular Diseases-B (JM
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Coronary Disease; Dia | 2004 |
Comparison of the effects of telmisartan and nifedipine gastrointestinal therapeutic system on blood pressure control, glucose metabolism, and the lipid profile in patients with type 2 diabetes mellitus and mild hypertension: a 12-month, randomized, doubl
Topics: Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Glucose; Blood Pressure; Cholesterol; Chol | 2004 |
Long-term renoprotection by perindopril or nifedipine in non-hypertensive patients with Type 2 diabetes and microalbuminuria.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diabetes Mel | 2004 |
Effects of calcium antagonists in hypertensive patients with renal dysfunction: a prospective, randomized, parallel trial comparing benidipine and nifedipine.
Topics: Calcium Channel Blockers; Dihydropyridines; Disease Progression; Female; Humans; Hypertension; Hyper | 2004 |
Effects of valsartan and nifedipine coat-core on systemic arterial stiffness in hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Flow Velocity; Blo | 2004 |
Effects of nifedipine GITS and diuretics in isolated systolic hypertension--a subanalysis of the INSIGHT study.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocker | 2004 |
Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Flow Velocity; Blood P | 2005 |
Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Flow Velocity; Blood P | 2005 |
Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Flow Velocity; Blood P | 2005 |
Antihypertensive therapy increases cerebral blood flow and carotid distensibility in hypertensive elderly subjects.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Flow Velocity; Blood P | 2005 |
Controlled-release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension: the NICE Combi (Nifedipine and Candesartan Combination) Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Albuminuria; Antihypertensive Agents; Benzimidazoles; Bi | 2005 |
The effect of combination therapy on regression of left ventricular hypertrophy in cases with hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Ch | 2004 |
Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with symptomatic stable angina and hypertension: the ACTION trial.
Topics: Adrenergic beta-Antagonists; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Corona | 2005 |
Comparison between nifedipine and carvedilol in the treatment of de novo arterial hypertension after liver transplantation: preliminary results of a controlled clinical trial.
Topics: Blood Pressure; Carbazoles; Carvedilol; Female; Heart Rate; Humans; Hypertension; Liver Transplantat | 2005 |
Effect of telmisartan/hydrochlorothiazide combination versus nifedipine GITS on ambulatory blood pressure and sympathetic activation.
Topics: Adult; Aged; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug | 2005 |
[Efficacy and tolerability of two forms of nifedipine in the treatment of hypertension].
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-Response Relat | 2005 |
Effects of nilvadipine and amlodipine in patients with mild to moderate essential hypertension: a double blind, prospective, randomised clinical trial.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocke | 2005 |
Effects of nifedipine GITS 20 mg or enalapril 20 mg on blood pressure and inflammatory markers in patients with mild-moderate hypertension.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Determination; | 2005 |
Single- or double-blind treatment With Balsamodendron mukul and nifedipine in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combinatio | 2005 |
[Non-hemodynamic effects of calcium channel blocker nifedipine: effects on functional activity of blood cells and endothelium].
Topics: Antigens, CD; Calcium Channel Blockers; Endothelium, Vascular; Female; Hemodynamics; Humans; Hyperte | 2005 |
[Efficacy of antihypertensive drugs in pregnancy].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Female; Hemod | 2005 |
Cost-effectiveness analysis of hypertension treatment: controlled release nifedipine and candesartan low-dose combination therapy in patients with essential hypertension--the Nifedipine and Candesartan Combination (NICE-Combi) Study.
Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Ch | 2005 |
Beneficial effect of T-type calcium channel blockers on endothelial function in patients with essential hypertension.
Topics: Adult; Aged; Blood Flow Velocity; Brachial Artery; Calcium Channel Blockers; Case-Control Studies; D | 2005 |
Long-term treatment with imidapril but not with nifedipine enhances plasma NOx concentration in patients with essential hypertension.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Female; Humans; Hyperten | 2006 |
Synergistic effect of ginger and nifedipine on human platelet aggregation: a study in hypertensive patients and normal volunteers.
Topics: Adenosine Diphosphate; Adult; Collagen; Drug Synergism; Epinephrine; Female; Humans; Hypertension; M | 2006 |
Control of edema in hypertensive subjects treated with calcium antagonist (nifedipine) or angiotensin-converting enzyme inhibitors with Pycnogenol.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Capilla | 2006 |
[Rational approach to selection of antihypertensive therapy in persons with metabolic syndrome: efficacy of monotherapy with spirapril and its combination with retard form of nifedipine].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cholesterol, LDL; Drug Th | 2006 |
[The effects of antidepressant treatment on efficacy of antihypertensive therapy in elderly hypertension].
Topics: Aged; Antidepressive Agents; Antidepressive Agents, Second-Generation; Antihypertensive Agents; Bloo | 2006 |
[Individualising the evidence--single case randomized trial].
Topics: Adrenergic alpha-Antagonists; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double | 2006 |
Intravenous nifedipine for control of hypertension in patients after coronary artery bypass graft surgery.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Coronary Artery Bypass; Coronary Circulation; Dose-Resp | 1988 |
Chronic treatment with long-acting nifedipine reduces vasoconstriction to endothelin-1 in essential hypertension.
Topics: Acetylcholine; Adult; Brachial Artery; Calcium Channel Blockers; Delayed-Action Preparations; Dose-R | 2007 |
Effect of barnidipine on blood pressure and serum metabolic parameters in patients with essential hypertension: a pilot study.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Aged; Antihypertensive Agents; Aryldialkylphosphatas | 2006 |
Controlled release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-combi) study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analysi | 2006 |
Favourable effects of nilvadipine on cognitive function and regional cerebral blood flow on SPECT in hypertensive patients with mild cognitive impairment.
Topics: Aged; Amlodipine; Antihypertensive Agents; Brain; Cerebrovascular Circulation; Cognition Disorders; | 2007 |
Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarcti | 2007 |
Dose- and administration time-dependent effects of nifedipine gits on ambulatory blood pressure in hypertensive subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Chronotherapy; Circadian Rhythm; Dose-Response Rela | 2007 |
Angiotensin receptor blocker improves coronary flow velocity reserve in hypertensive patients: comparison with calcium channel blocker.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Flow Velocity; Blood Pressure; Calcium Channel | 2007 |
Crossover study of amlodipine versus nifedipine CR with home blood pressure monitoring via cellular phone: internet-mediated open-label crossover trial of calcium channel blockers for hypertension (i-TECHO trial).
Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Calcium Channel Blockers; Cell Phone; Cross-O | 2007 |
The relationship between the acute changes of the systolic blood pressure and the brachial-ankle pulse wave velocity.
Topics: Administration, Sublingual; Aged; Blood Flow Velocity; Blood Pressure; Brachial Artery; Female; Huma | 2007 |
Formulation of long-acting nifedipine tablets influences the heart rate and sympathetic nervous system response in hypertensive patients.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cross-Over Studies; Drug | 2008 |
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relation | 2007 |
High doses of lercanidipine are better tolerated than other dihydropyridines in hypertensive patients with metabolic syndrome: results from the TOLERANCE study.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Cross-Sectio | 2008 |
Tolerability of high doses of lercanidipine versus high doses of other dihydropyridines in daily clinical practice: the TOLERANCE Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Sectional | 2008 |
Antihypertensive effects on blood pressure at rest and during exercise of calcium antagonists, beta-receptor blockers, and their combination in hypertensive patients.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Chol | 1984 |
Efficacy of nitrendipine as baseline antihypertensive therapy.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Heart Rate; Humans; Hyper | 1984 |
Nitrendipine in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Black People; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Doubl | 1984 |
Clinical experience with long-term nitrendipine treatment in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Proteins; Body Weight; Calcium; Calcium Channel Blockers; Clinica | 1984 |
Crossover comparison of nitrendipine with propranolol in patients with essential hypertension.
Topics: Adult; Blood Pressure; Body Weight; Calcium Channel Blockers; Catecholamines; Humans; Hypertension; | 1984 |
Comparison of nitrendipine combined with low-dose hydrochlorothiazide to hydrochlorothiazide alone in mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method | 1984 |
Efficacy and safety comparison of nitrendipine and hydralazine as antihypertensive monotherapy.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method | 1984 |
Calcium channel blockers as antihypertensive agents.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Disease; | 1984 |
Relationship between the antihypertensive effect and steady-state plasma concentration of nifedipine given alone or in combination with a beta-adrenoceptor blocking agent.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Humans; Hypertension; M | 1980 |
Calcium antagonists, firstline partners for betablockers in hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dil | 1984 |
Effects and mechanism of nifedipine after oral, sublingual, intravenous and intracoronary administration. Survey on clinical results.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Clinical Trials as Topic; Double-Blind Method; Drug Th | 1984 |
Antihypertensive and humoral effects of verapamil and nifedipine in essential hypertension.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Blockers; | 1982 |
Acute antihypertensive and hormonal effects of a calcium antagonist in essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hormones; Humans; Hypertension; N | 1982 |
Verapamil compared with nifedipine in the treatment of essential hypertension.
Topics: Adult; Body Weight; Calcium Channel Blockers; Creatinine; Double-Blind Method; Electrocardiography; | 1982 |
Experience with nitrendipine--a new calcium antagonist--in hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Fema | 1982 |
Clinical use of calcium channel blockers as ventricular unloading agents.
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Top | 1983 |
Calcium channel blocking agents.
Topics: Benzazepines; Calcium; Calcium Channel Blockers; Cardiomegaly; Clinical Trials as Topic; Coronary Di | 1981 |
[Effect of cimetidine and ranitidine on the pharmacokinetics and anti-hypertensive effect of nifedipine].
Topics: Adult; Blood Pressure; Cimetidine; Clinical Trials as Topic; Drug Administration Schedule; Drug Inte | 1983 |
[Clinical usefulness of nifedipine in the treatment of hypertensive crisis].
Topics: Clinical Trials as Topic; Female; Humans; Hypertension; Male; Nifedipine; Pyridines | 1983 |
[Hypertension treatment with nifedipine (Corinfar)].
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 1983 |
[Antihypertensive efficacy of nifedipine. Clinical and ergometric evaluation].
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Female; Hemodynamics; Humans; Hypertension; Ma | 1983 |
Disparate unloading efficacy of the calcium channel blockers, verapamil and nifedipine, on the failing hypertensive left ventricle.
Topics: Cardiac Output; Clinical Trials as Topic; Echocardiography; Female; Heart Failure; Heart Ventricles; | 1984 |
Calcium-channel blockade with nifedipine and angiotensin converting-enzyme inhibition with captopril in the therapy of patients with severe primary hypertension.
Topics: Adult; Blood Pressure; Blood Urea Nitrogen; Captopril; Drug Therapy, Combination; Female; Heart Rate | 1984 |
Acute antihypertensive effect of nifedipine by sublingual route in cases with clinically severe systolic hypertension. A study up to 4 h after administration.
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic | 1984 |
Comparison of nifedipine (retard formulation) and mefruside in the treatment of mild to moderate hypertension--a prospective randomized double-blind crossover study in general practice.
Topics: Clinical Trials as Topic; Diuretics; Double-Blind Method; Female; Humans; Hypertension; Male; Mefrus | 1984 |
Acebutolol and nifedipine in the treatment of arterial hypertension: efficacy and acceptability.
Topics: Acebutolol; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Drug Therapy, C | 1984 |
Changes in left ventricular mass during a double-blind study with chlorthalidone and slow-release nifedipine.
Topics: Adult; Blood Pressure; Chlorthalidone; Clinical Trials as Topic; Delayed-Action Preparations; Double | 1984 |
[Comparative double-blind, randomized, crossover study controlled with placebo, of the efficacy of depot nifedipine in patients refractory to basic antihypertensive therapy].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Met | 1984 |
[Comparative double-blind, crossover and randomized study of the antihypertensive activity of nifedipine in primary arterial hypertension].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; F | 1984 |
[Comparison of the anti-hypertensive effects of combinations of nifedipine retard with acebutolol or atenolol].
Topics: Acebutolol; Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Fe | 1984 |
Hypotensive action of calcium antagonists as related to plasma noradrenaline and reactivity to noradrenaline.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Humans; Hypertension; Male; Nif | 1983 |
Nifedipine in hypertensive emergencies.
Topics: Adult; Aged; Blood Pressure; Cerebrovascular Circulation; Clinical Trials as Topic; Clonidine; Emerg | 1983 |
Role of nifedipine in treatment of hypertension.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Administration Sche | 1983 |
Acute and chronic hypotensive effects of nifedipine and niludipine in hypertensive patients with chronic renal failure.
Topics: Adolescent; Adult; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Female; Humans; Hyper | 1984 |
[Treatment of arterial hypertension in the aged with a calcium antagonist: nicardipine].
Topics: Aged; Calcium Channel Blockers; Double-Blind Method; Drug Evaluation; Female; Humans; Hypertension; | 1984 |
A study of the antihypertensive effect and some pharmacodynamic aspects of nifedipine in medium-term treatment.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Humans; Hypert | 1984 |
Effects of nitrendipine and hydralazine on plasma catecholamines in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Chromatography, High Pressure Liquid; Dopamine; Drug Evaluation; Epinep | 1984 |
Role of nifedipine in the treatment of resistant hypertension. Comparison with hydralazine in hospital outpatients.
Topics: Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Male; Middle Aged; Nifedipine; Outpa | 1984 |
[Hypotensive properties of nisoldipine. Comparative study in essential, renal and renovascular hypertension].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Electrolytes; Female; Heart Rate; Humans; Hydroc | 1984 |
Detection of a diurnal rhythm in arterial blood pressure in the evaluation of 24-hour antihypertensive therapy.
Topics: Adult; Aged; Ambulatory Care; Blood Pressure Determination; Circadian Rhythm; Humans; Hypertension; | 1984 |
Pressor factors and cardiovascular pressor responsiveness after short-term antihypertensive therapy with the calcium antagonist nifedipine alone or combined with a diuretic.
Topics: Adult; Aged; Blood Pressure; Cardiovascular System; Chlorthalidone; Drug Evaluation; Drug Therapy, C | 1984 |
Blockade of slow calcium channels and regulation of circulatory pressor responses in uncomplicated hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertens | 1983 |
Antihypertensive effects at rest and during exercise of a calcium blocker, nifedipine, alone and in combination with metoprolol.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; He | 1982 |
Nifedipine in the treatment of hypertension: report of a double-blind controlled trial.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Diuretics; Double-Blind Method; | 1982 |
Acute hypotensive, hemodynamic effects of long-term treatment with niludipine, a Ca2+-antagonist, in patients with essential hypertension. Niludipine monotherapy and combination with a beta-blocker and a diuretic).
Topics: Adult; Benzothiadiazines; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Femal | 1982 |
[Calcium antagonists in the treatment of arterial hypertension].
Topics: Benzazepines; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; | 1982 |
[Labetalol in the treatment of arterial hypertension. A Brazilian multicenter study].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therap | 1982 |
[Nifedipine in the treatment of essential hypertension].
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Hemodynamics; Humans; Hypertension; Isometric | 1982 |
Reduced pressor effect of angiotensin II and of noradrenaline in normal man following the oral administration of the calcium-antagonist nifedipine.
Topics: Administration, Oral; Adult; Aldosterone; Angiotensin II; Blood Pressure; Calcium Channel Blockers; | 1982 |
The combination of propranolol and nifedipine in the treatment of hypertension: acute and long term effects.
Topics: Adult; Aged; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged; Nifedipine; Propran | 1983 |
Antihypertensive effect of fractionated sublingual administration of nifedipine in moderate essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Clinical Trials a | 1980 |
[Nifedipine and essential arterial hypertension refractory to hypotensive therapy: results of a preliminary double-blind study].
Topics: Adult; Aged; Chlorthalidone; Clinical Trials as Topic; Clonidine; Double-Blind Method; Female; Human | 1981 |
Antihypertensive and hormonal effects of single oral doses of captopril and nifedipine in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Captopril; Female; Humans; Hypertension; Male; Middl | 1981 |
[Dilzem: a new alternative to the therapy of angina pectoris and hypertension].
Topics: Angina Pectoris; Arrhythmias, Cardiac; Benzazepines; Calcium Channel Blockers; Clinical Trials as To | 1981 |
Abnormalities and drug-induced alterations of vasopressin in human hypertension.
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle Aged; N | 1981 |
Calcium blockers: more than angina.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Muscl | 1982 |
Effects of treatment with nifedipine and metoprolol in essential hypertension.
Topics: Adult; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension | 1982 |
A study on the effects of niludipine in hypertensive patients.
Topics: Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Place | 1982 |
Short- and long-term efficacy of a calcium-antagonistic agent (nifedipine) combined with methyldopa in the treatment of severe hypertension.
Topics: Drug Therapy, Combination; Edema; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Methyldopa; | 1980 |
[Can the "double blind" be recognized before the identifying codes are revealed?].
Topics: Albuminuria; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Hy | 1995 |
[Comparison of treatment effects with an angiotensin converting enzyme inhibitor--lisinopril and a calcium blocker--nifedipine retard on urinary albumin excretion in patients with non-complicated essential hypertension].
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blocke | 1995 |
Comparative efficacy of two long-acting formulations of nifedipine in the treatment of hypertension. The Switch Study Investigators.
Topics: Adolescent; Adult; Aged; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Middle Age | 1995 |
[The effect of long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents on the quality of life in patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working
Topics: Adult; Antihypertensive Agents; Azerbaijan; Captopril; Humans; Hydrochlorothiazide; Hypertension; Ma | 1995 |
Indapamide reduces hypertensive left ventricular hypertrophy: an international multicenter study.
Topics: Adult; Aged; Atenolol; Blood Pressure; Double-Blind Method; Enalapril; Female; France; Humans; Hydro | 1993 |
Side effects of dihydropyridine therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Blood Pressure; Delayed-Action Preparations; Drug Admini | 1993 |
Comparison of the efficacy and safety of trandolapril and nifedipine SR in mild-to-moderate hypertension. Investigator Study Group.
Topics: Angiotensin-Converting Enzyme Inhibitors; Delayed-Action Preparations; Female; Humans; Hypertension; | 1994 |
Pharmacokinetic profile of nifedipine GITS in hypertensive patients with chronic renal impairment.
Topics: Administration, Oral; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Kidney Diseases; Mal | 1994 |
The 24-hour efficacy of a new once-daily formulation of nifedipine. Italian Nifedipine GITS Study Group.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Mi | 1994 |
Differential effects of felodipine and nifedipine on 24-h blood pressure and left ventricular mass.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, | 1995 |
Factors determining the blood pressure response to enalapril and nifedipine in hypertension associated with NIDDM.
Topics: Albuminuria; Aldosterone; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Glucose; Blood P | 1995 |
Determination of systemic haemodynamic alterations induced by slow-release nifedipine in elderly hypertensive patients using a non-invasive method: double-blind cross-sectional random study.
Topics: Aged; Blood Pressure Determination; Cross-Sectional Studies; Delayed-Action Preparations; Double-Bli | 1995 |
Antihypertensive effects of moexipril, a new ACE inhibitor, as add-on therapy to nifedipine in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Press | 1995 |
Contribution of atrial reservoir function to ventricular filling in hypertensive patients. Effects of nifedipine administration.
Topics: Adult; Aged; Atrial Function, Left; Blood Flow Velocity; Female; Humans; Hypertension; Male; Middle | 1995 |
Assessment of the Vital Signs Quality of Life Questionnaire in three studies on hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans | 1995 |
Nilvadipine increases cerebral blood flow in elderly hypertensives: comparison with nifedipine.
Topics: Aged; Aging; Antihypertensive Agents; Aorta; Cerebrovascular Circulation; Compliance; Cross-Over Stu | 1995 |
A long-term study comparing lacidipine and nifedipine SR in hypertensive patients: safety data.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Delayed-Ac | 1994 |
Calcium antagonist antihypertensive treatment of non-insulin-dependent diabetics: efficacy and safety of lacidipine versus nifedipine SR.
Topics: Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cholesterol; Delay | 1994 |
Effects of lacidipine and nifedipine on lower limb veins in nonphlebopathic patients.
Topics: Adult; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Double-Blind Method; | 1994 |
The use of lacidipine in the management of hypertensive crises: a comparative study with nifedipine.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel | 1994 |
Angiotensin-converting enzyme inhibition in diabetic nephropathy: ten years' experience.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Bendroflumethiazide; Blood Pressure; C | 1995 |
[Use of carvedilol compared to nifedipine in the treatment of mild and moderate essential arterial hypertension].
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Carbazoles; Carvedilol; Clinical Protocols; Del | 1994 |
Effect of dose adjustment on enalapril-induced cough and the response to inhaled capsaicin.
Topics: Administration, Inhalation; Adult; Aged; Analysis of Variance; Capsaicin; Cough; Cross-Over Studies; | 1995 |
[Nilvadipin for nifedipine induced calf edema. Results of a double blind randomized comparative study].
Topics: Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Double-Blind Method; Edema; Female; Hea | 1994 |
[The long-term monotherapy with preparations from the 4 basic groups of antihypertensive agents of patients with mild and moderate arterial hypertension. The Multicenter Captopril and the Quality of Life Study. The working group of the Multicenter Captopr
Topics: Adult; Azerbaijan; Captopril; Hemodynamics; Humans; Hydrochlorothiazide; Hypertension; Male; Middle | 1995 |
Regulation of sodium excretion in human hypertension: long-term effects of calcium antagonist and angiotensin converting enzyme inhibitor.
Topics: Adult; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Calcium Cha | 1993 |
Effectiveness of nifedipine gastrointestinal therapeutic system for treatment of hypertension: results of the MATH Trial.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Delayed-Action Preparations; Drug Delivery System | 1993 |
Hemodynamic and humoral effects of the angiotensin II antagonist losartan in essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bod | 1994 |
Use of drugs with more than a twenty-four-hour duration of action.
Topics: Aged; Amlodipine; Cross-Over Studies; Drug Administration Schedule; Female; Humans; Hypertension; Ma | 1994 |
Invasive hemodynamic evaluation of sublingual captopril and nifedipine in patients with arterial hypertension after abdominal aortic surgery.
Topics: Administration, Sublingual; Aged; Analysis of Variance; Aorta, Abdominal; Captopril; Female; Hemodyn | 1995 |
Metabolic effects of anti-hypertensive treatment with nifedipine or furosemide: a double-blind, cross-over study.
Topics: Aged; Analysis of Variance; Body Weight; Cross-Over Studies; Double-Blind Method; Female; Furosemide | 1995 |
The influence of nimodipine on hemodynamic parameters and peak and trough plasma concentrations of nifedipine chronically administered to elderly hypertensive patients.
Topics: Aged; Blood Pressure; Cross-Over Studies; Delayed-Action Preparations; Double-Blind Method; Drug Int | 1995 |
Patient compliance and therapeutic coverage: comparison of amlodipine and slow release nifedipine in the treatment of hypertension. The Belgian Collaborative Study Group.
Topics: Amlodipine; Cross-Over Studies; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Mid | 1995 |
[Clinical experience with alpha blockers and calcium antagonists in the perioperative treatment of pheochromocytoma].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Aged; Humans; Hypertension; Male; Nifedipine; Phenoxyben | 1994 |
Comparative effects of fosinopril and nifedipine on regression of left ventricular hypertrophy in hypertensive patients: a double-blind study.
Topics: Blood Pressure; Blood Pressure Determination; Double-Blind Method; Drug Therapy, Combination; Echoca | 1995 |
Vasodilators: scorpion envenoming and the heart (an Indian experience).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Bradycardia; Cardiovascular Diseases; Child; Ch | 1994 |
Effect of two different therapeutic approaches on total and cardiovascular mortality in a Cardiovascular Study in the Elderly (CASTEL).
Topics: Aged; Aged, 80 and over; Atenolol; Chlorthalidone; Clonidine; Drug Therapy, Combination; Female; Hea | 1994 |
Lisinopril versus slow release nifedipine in patients with essential hypertension: a multicentre study.
Topics: Blood Cell Count; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Heart Ra | 1994 |
Female preponderance for lisinopril-induced cough in hypertension.
Topics: Adult; Aged; Cough; Double-Blind Method; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged | 1994 |
Differential effects of chronic oral antihypertensive therapies on systemic arterial circulation and ventricular energetics in African-American patients.
Topics: Administration, Oral; Analysis of Variance; Antihypertensive Agents; Atenolol; Black People; Cross-O | 1995 |
Within-patient correlation between the antihypertensive effects of atenolol, lisinopril and nifedipine.
Topics: Adolescent; Adult; Age Factors; Aged; Atenolol; Blood Pressure; Blood Pressure Monitoring, Ambulator | 1994 |
Prediction and optimisation of the antihypertensive response to nifedipine.
Topics: Blood Pressure; Computer Simulation; Delayed-Action Preparations; Dose-Response Relationship, Drug; | 1994 |
Lisinopril improves aortic compliance and renal flow. Comparison with nifedipine.
Topics: Aged; Aorta; Compliance; Female; Hemodynamics; Humans; Hypertension; Lisinopril; Male; Nifedipine; P | 1995 |
Morning versus evening administration of nifedipine gastrointestinal therapeutic system in the management of essential hypertension.
Topics: Aged; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Cross-Over Studies; Double-Blind Meth | 1994 |
Nifedipine kinetics and dynamics in hypertensive patients: a new approach.
Topics: Aged; Blood Pressure; Chromatography, High Pressure Liquid; Female; Half-Life; Humans; Hypertension; | 1994 |
A comparison of nifedipine with methyldopa in pregnancy induced hypertension.
Topics: Adult; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pregnancy; Pregnancy Complications, Car | 1994 |
[Time of drug intake in hypertension and angina pectoris. A controlled monitoring study].
Topics: Aged; Amlodipine; Angina Pectoris; Confidence Intervals; Cross-Over Studies; Female; Humans; Hyperte | 1994 |
Long-term protective effect of a calcium antagonist on renal function in hypertensive renal transplant patients on cyclosporine therapy: a 5-year prospective randomized study.
Topics: Analysis of Variance; Antihypertensive Agents; Cadaver; Creatinine; Cyclosporine; Female; Follow-Up | 1994 |
A comparative study of long acting diltiazem (Tildiem LA) with sustained release nifedipine (nifedipine SR) and bendrofluazide in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Delaye | 1994 |
Effects of celiprolol vs. nifedipine on serum lipoproteins in patients with mild to moderate hypertension.
Topics: Adult; Aged; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins B; Blood Pressure; Celiprolol; | 1994 |
The effects of enalapril and nifedipine on carbohydrate and lipid metabolism in NIDDM.
Topics: Apolipoprotein A-I; Apolipoproteins B; Biomarkers; Blood Glucose; Blood Pressure; China; Cholesterol | 1994 |
Trough and peak effects of a single daily dose of nifedipine gastrointestinal therapeutic system (GITS) as assessed by ambulatory blood pressure monitoring. Italian Nifedipine GITS Study Group.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Delayed-Action Preparations | 1994 |
[Does long-term blood pressure reduction in patients with essential hypertension improve concomitant metabolic disorders?].
Topics: Adult; Blood Glucose; Blood Pressure; Body Composition; Body Mass Index; Female; Follow-Up Studies; | 1994 |
[Comparative and double-blind study of the efficacy and safety of cilazapril compared to nifedipine retard in the treatment of mild and moderate arterial hypertension].
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cilazapril; Double-Blind Method; Fe | 1994 |
Controlled study with a new sustained-release formulation of nifedipine in essential hypertensive patients.
Topics: Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up St | 1994 |
Acute natriuretic effect of nifedipine on different sodium intakes in essential hypertension: evidence for distal tubular effect?
Topics: Adult; Aged; Blood Pressure; Body Weight; Cross-Over Studies; Double-Blind Method; Female; Humans; H | 1994 |
A comparison of lisinopril and nifedipine in the treatment of mild to moderate hypertension. A multicentre study.
Topics: Adolescent; Adult; Aged; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine | 1994 |
Renal effects of nifedipine and captopril in patients with essential hypertension and reduced renal reserve.
Topics: Adult; Captopril; Diuresis; Female; Hemodynamics; Humans; Hypertension; Kidney; Male; Middle Aged; N | 1994 |
[Lisinopril and nifedipine have neutral effects on lipids].
Topics: Adult; Double-Blind Method; Female; Humans; Hypertension; Lipids; Lisinopril; Male; Middle Aged; Nif | 1994 |
Antihypertensive efficacy and tolerability of different drug regimens in isolated systolic hypertension in the elderly.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Chlorthalidon | 1994 |
Double-blind crossover study of once daily nifedipine coat core in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Me | 1994 |
Comparative study of buccoadhesive formulations and sublingual capsules of nifedipine.
Topics: Adhesiveness; Administration, Buccal; Administration, Sublingual; Adult; Blood Pressure; Capsules; D | 1994 |
Normalization of cardiac structure and function after regression of cardiac hypertrophy.
Topics: Adult; Case-Control Studies; Heart Ventricles; Hemodynamics; Humans; Hypertension; Hypertrophy, Left | 1994 |
Treatment of hypertensive emergency. Comparison of a new dosage form of the calcium antagonist nitrendipine with nifedipine capsules.
Topics: Administration, Oral; Adult; Aged; Capsules; Chi-Square Distribution; Double-Blind Method; Emergenci | 1994 |
Effects of manidipine hydrochloride on blood pressure in hypertensive patients--a comparison with nifedipine retard.
Topics: Adult; Aged; Blood Pressure; Dihydropyridines; Female; Humans; Hypertension; Male; Middle Aged; Nife | 1993 |
Nifedipine versus captopril in the management of moderate hypertension in black patients.
Topics: Adult; Aged; Black People; Blood Pressure; Captopril; Echocardiography; Humans; Hypertension; Middle | 1994 |
Effects of long-term enalapril treatment on persistent micro-albuminuria in well-controlled hypertensive and normotensive NIDDM patients.
Topics: Acetylglucosaminidase; Albuminuria; beta 2-Microglobulin; Blood Pressure; Body Weight; Cholesterol; | 1994 |
Intracellular ionic consequences of dietary salt loading in essential hypertension. Relation to blood pressure and effects of calcium channel blockade.
Topics: Analysis of Variance; Blood Pressure; Calcium; Electrolytes; Erythrocytes; Female; Humans; Hydrogen- | 1994 |
[The clinical efficacy of the new delayed-action calcium antagonist Cordipin-Retard].
Topics: Adult; Antihypertensive Agents; Delayed-Action Preparations; Hemodynamics; Humans; Hypertension; Mal | 1993 |
[Effect of nilvadipine on nifedipine-induced edema of the lower leg. Results of a double-blind randomized comparative study].
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans | 1994 |
Noninvasive assessment of the direct action of oral nifedipine and nicardipine on left ventricular contractile state in patients with systemic hypertension: importance of reflex sympathetic responses.
Topics: Adrenergic beta-Antagonists; Adult; Double-Blind Method; Echocardiography, Doppler; Heart Ventricles | 1993 |
Comparison of captopril, hydralazine and nifedipine as third drug in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Benzothiadiazines; Captopril; Diuretics; Drug Therapy, Combinati | 1993 |
[Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually].
Topics: Administration, Sublingual; Aged; Aortic Aneurysm, Abdominal; Captopril; Drug Evaluation; Humans; Hy | 1993 |
Calcium antagonist-induced gingival hyperplasia.
Topics: Adult; Aged; Calcium Channel Blockers; Cross-Sectional Studies; Diltiazem; Gingival Hyperplasia; Hum | 1994 |
A comparison of the effects of nifedipine and verapamil on exercise performance in patients with mild to moderate hypertension.
Topics: Double-Blind Method; Exercise Test; Hemodynamics; Hormones; Humans; Hypertension; Male; Middle Aged; | 1993 |
Lipids and cardiovascular reactivity changes in hypertensive cigarette smokers: enalapril versus nifedipine treatment effects.
Topics: Adult; Aged; Blood Pressure; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; | 1994 |
[The effect of monotherapy with nifedipine and hydrochlorothiazide on the psychological characteristics and quality of life of hypertension patients].
Topics: Adult; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedipine; Psychological Tests | 1993 |
Antihypertensive efficacy of a slow release nifedipine tablet formulation given once daily in patients with mild to moderate hypertension. A placebo-controlled, double-blind parallel-group trial.
Topics: Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Humans; | 1994 |
Double-blind comparison of amlodipine and nifedipine retard in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Aging; Amlodipine; Blood Pressure; Double-Blind Method; Drug Administration Schedule; F | 1994 |
Antihypertensive effects of nifedipine gastrointestinal therapeutic system on clinic and ambulatory blood pressure in essential hypertensives. Italian GITS Study Group.
Topics: Blood Pressure; Blood Pressure Monitors; Delayed-Action Preparations; Digestive System; Double-Blind | 1993 |
[The comparative effect of calcium antagonists on hemodynamics in patients with a stable form of essential hypertension (a randomized study)].
Topics: Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hemodynamics; Humans; Hyperte | 1994 |
Comparison of cilazapril and nifedipine retard on ambulatory blood pressure, metabolic, rheological and platelet function in hypertensive patients.
Topics: Blood Platelets; Blood Pressure; Cilazapril; Delayed-Action Preparations; Dose-Response Relationship | 1994 |
ACE inhibition versus calcium antagonism in the treatment of mild to moderate hypertension: a multicentre study. Ireland-Netherlands Lisinopril-Nifedipine Study Group.
Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Lisinopr | 1993 |
Sublingual captopril in hypertensive urgencies.
Topics: Administration, Sublingual; Captopril; Emergencies; Humans; Hypertension; Nifedipine | 1993 |
Transdermal clonidine as an adjunct to nifedipine-GITS therapy in patients with mild-to-moderate hypertension.
Topics: Administration, Cutaneous; Adult; Aged; Blood Pressure; Chemotherapy, Adjuvant; Clonidine; Female; H | 1993 |
Slowing of mitral valve annular calcium in systemic hypertension by nifedipine and comparisons with enalapril and atenolol.
Topics: Adult; Atenolol; Calcinosis; Echocardiography, Doppler; Enalapril; Female; Heart Valve Diseases; Hum | 1993 |
Effect and tolerability of combining lovastatin with nifedipine or lisinopril.
Topics: Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypercholesterole | 1993 |
[Evaluation of a combination of a diuretic and nifedipine retard for the treatment of hypertensive patients refractory to nifedipine retard].
Topics: Aged; Aged, 80 and over; Chlorthalidone; Delayed-Action Preparations; Drug Therapy, Combination; Fem | 1993 |
Increased blood pressure and neural tone in the silent ischemia of hypertension: disparate effects of immediate release nifedipine.
Topics: Activities of Daily Living; Adult; Aged; Angina Pectoris; Blood Pressure; Circadian Rhythm; Echocard | 1993 |
Intravenous urapidil versus sublingual nifedipine in the treatment of hypertensive urgencies.
Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; | 1993 |
[Differential use of vasodilators in various types of cardiac insufficiency].
Topics: Adult; Aged; Blood Pressure; Captopril; Cardiomyopathy, Dilated; Female; Humans; Hypertension; Male; | 1993 |
Comparison of sublingual captopril, nifedipine and prazosin in hypertensive emergencies during hemodialysis.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Captopril; Chemistry, Pharmaceutical; Femal | 1993 |
Modification of exercise performance by sharp reduction of blood pressure. A study in patients with uncomplicated hypertension.
Topics: Anaerobic Threshold; Blood Pressure; Captopril; Double-Blind Method; Exercise Tolerance; Female; Hum | 1993 |
Improved baroreflex sensitivity in elderly hypertensives on lisinopril is not explained by blood pressure reduction alone.
Topics: Aged; Ambulatory Care; Baroreflex; Blood Pressure; Blood Pressure Determination; Double-Blind Method | 1993 |
[Effect of long-term monotherapy with propranolol and nifedipine on the quality of life and psychological status of patients with hypertension].
Topics: Adult; Blood Pressure; Chronic Disease; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedip | 1993 |
The effect of N-3 fatty acids and nifedipine on platelet function in hypertensive males.
Topics: Adult; beta-Thromboglobulin; Bleeding Time; Blood Platelets; Docosahexaenoic Acids; Double-Blind Met | 1993 |
Effects of magnesium and nifedipine infusions on insulin action, substrate oxidation, and blood pressure in aged hypertensive patients.
Topics: Aged; Aging; Blood Glucose; Blood Pressure; Body Mass Index; Calcium; Calorimetry; Drug Synergism; E | 1993 |
Effects of dilevalol (R,R-labetalol) compared with nifedipine on heart rate, blood pressure and muscle blood flow at rest and on exercise in hypertensive patients.
Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Exercise; Heart Rate; Humans; Hyperten | 1993 |
[Long-term effects of captopril versus nifedipine retard on the lipid profile of mild to moderate normolipidemic essential hypertension patients. In representation of the Eastern Andalouz Cooperative Study].
Topics: Adult; Captopril; Delayed-Action Preparations; Female; Humans; Hypertension; Lipids; Male; Middle Ag | 1993 |
Calcium antagonists in heart transplant recipients: effects on cardiac and renal function and cyclosporine pharmacokinetics.
Topics: Cyclosporine; Diltiazem; Heart Transplantation; Hemodynamics; Humans; Hypertension; Immunosuppressio | 1993 |
Oral labetalol versus oral nifedipine in hypertensive urgencies in the ED.
Topics: Administration, Oral; Blood Pressure; Clinical Protocols; Diastole; Drug Administration Schedule; Em | 1993 |
Converting-enzyme inhibitor versus calcium antagonist in cyclosporine-treated renal transplants.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Cyclospori | 1993 |
Renal responses to nifedipine and captopril in hypertensive insulin-dependent diabetic men: a randomized cross-over study.
Topics: Adult; Albuminuria; Blood Pressure; Captopril; Diabetes Mellitus, Type 1; Double-Blind Method; Human | 1993 |
[The effect of nifedipine in hypertensive cardiopathy. An echocardiographic and electrocardiographic study].
Topics: Adult; Analysis of Variance; Echocardiography; Electrocardiography; Female; Hemodynamics; Humans; Hy | 1993 |
Effect of prolonged nifedipine or captopril therapy on lymphocyte magnesium and potassium levels in hypertension.
Topics: Adult; Aged; Captopril; Female; Humans; Hypertension; Lymphocytes; Magnesium; Male; Middle Aged; Nif | 1993 |
Comparison of the effects of an angiotensin converting enzyme inhibitor and a calcium antagonist in hypertensive, macroproteinuric diabetic patients: a randomised double-blind study.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 1993 |
Double-blind comparison between nifedipine and amlodipine for the treatment of essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Double-Blind Method; Female; Hormones; Humans; Hypertension | 1993 |
Harmonic regression analysis of the effect of drug treatment on the diurnal rhythm of blood pressure and angina.
Topics: Amlodipine; Angina Pectoris; Blood Pressure; Circadian Rhythm; Double-Blind Method; Humans; Hyperten | 1993 |
Effects of fish oil, nifedipine and their combination on blood pressure and lipids in primary hypertension.
Topics: Adult; Blood Pressure; Cholesterol; Docosahexaenoic Acids; Double-Blind Method; Drug Therapy, Combin | 1993 |
Early side-effects of antihypertensive therapy: comparison of amlodipine and nifedipine retard.
Topics: Adult; Aged; Amlodipine; Delayed-Action Preparations; Dizziness; Double-Blind Method; Edema; Female; | 1993 |
Effects of atenolol withdrawal in patients on triple antihypertensive therapy.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Captopril; Double-Blind Method; Drug Therapy, Combinatio | 1993 |
[Evaluation of the efficacy and tolerance of three antihypertensive agents used as single-drug therapy, nifedipine, prazosin and acebutolol in severe, idiopathic hypertension in adolescents].
Topics: Acebutolol; Adolescent; Blood Glucose; Blood Pressure; Cholesterol, LDL; Clinical Protocols; Female; | 1993 |
Comparison of nifedipine and propranolol as second line agent for hypertension in black Kenyans.
Topics: Adult; Aged; Black People; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Humans; H | 1993 |
Hyperfiltration and conservation of renal function in hypertensive nephrosclerosis patients.
Topics: Adult; Aged; Analysis of Variance; Antihypertensive Agents; Enalapril; Female; Glomerular Filtration | 1993 |
Effects of isradipine and nifedipine retard in hypertensive patients with type II diabetes mellitus.
Topics: Blood Glucose; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Double-Blind Method; Female; | 1993 |
Effect of short-term antihypertensive therapy on left ventricular wall tension. A double-blind comparison of isradipine and nifedipine.
Topics: Cardiac Volume; Double-Blind Method; Female; Heart Ventricles; Humans; Hypertension; Isradipine; Mal | 1993 |
The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Diure | 1993 |
Effects of antihypertensive drugs atenolol and nifedipine on sexual function in older men: a placebo-controlled, crossover study.
Topics: Aged; Analysis of Variance; Atenolol; Double-Blind Method; Humans; Hypertension; Male; Middle Aged; | 1993 |
Nifedipine attenuates the hypertensive response to tracheal intubation in pregnancy-induced hypertension.
Topics: Administration, Sublingual; Adult; Anesthesia, Intravenous; Apgar Score; Blood Gas Analysis; Blood P | 1993 |
Comparison of nisoldipine and nifedipine as additional treatment in hypertension inadequately controlled by atenolol.
Topics: Atenolol; Black People; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension | 1993 |
Captopril-induced fall in glomerular filtration rate in cyclosporine-treated hypertensive patients.
Topics: Adult; Blood Pressure; Captopril; Cyclosporine; Female; Glomerular Filtration Rate; Humans; Hyperten | 1993 |
[A one year study of single administration of nilvadipine. Results of the effectiveness and long-term tolerance in hypertension].
Topics: Aged; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Long-Term Care; M | 1993 |
Blood pressure control effects on the progression of chronic renal failure.
Topics: Captopril; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Nifedipine; Pro | 1993 |
[The effect of hypotensive drugs on left ventricular mass and diastolic function].
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Drug Therapy, Combination; | 1995 |
[Multicenter National Study for the evaluation of the efficacy and tolerance of nifedipine oral release osmotic system in mild to moderate hypertension].
Topics: Administration, Oral; Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory | 1995 |
Addition of urapidil or metoprolol to the treatment of hypertensive non-responders to nifedipine monotherapy: efficacy and metabolic effects. Italian Urapidil Study Group.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cholesterol, HDL; Cholesterol, LDL; Drug Therapy, Co | 1995 |
Comparative effects of atenolol versus nifedipine on serum lipids and other biochemical parameters in diabetic and non-diabetic hypertensive subjects.
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Creatin | 1995 |
Time course of regression of vascular structural changes and its relation to cytosolic free calcium in hypertensives after nilvadipine treatment.
Topics: Adult; Aged; Analysis of Variance; Calcium; Calcium Channel Blockers; Cytosol; Female; Humans; Hyper | 1995 |
Influence of non-steroidal anti-inflammatory drugs on renal function and 24h ambulatory blood pressure-reducing effects of enalapril and nifedipine gastrointestinal therapeutic system in hypertensive patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cros | 1995 |
Hypertension and non-insulin-dependent diabetes. A comparison between an angiotensin-converting enzyme inhibitor and a calcium antagonist.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Glucose; Blood | 1995 |
Twenty-four-hour blood pressure monitoring during treatment with extended-release felodipine versus slow-release nifedipine: cross-over study.
Topics: Adolescent; Adult; Aged; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over | 1995 |
Sublingual nifedipine compared with intravenous hydrallazine in the acute treatment of severe hypertension in pregnancy: potential for use in rural practice.
Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hydra | 1996 |
Felodipine as an alternative to more expensive calcium antagonists in mild to moderate hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Drug Costs; Felo | 1996 |
[Hemodynamics in arterial hypertension treated with running endurance training or nifedipine therapy].
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Administrati | 1996 |
Comparison of nifedipine alone and with diltiazem or verapamil in hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Data Interpretation, Statistical; Diltiazem; Double | 1996 |
Effects of dihydropyridine calcium antagonists on albuminuria in patients with diabetes.
Topics: Adult; Albuminuria; Calcium Channel Blockers; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, S | 1996 |
Comparison of enalapril versus nifedipine to decrease left ventricular hypertrophy in systemic hypertension (the PRESERVE trial).
Topics: Antihypertensive Agents; Double-Blind Method; Echocardiography; Enalapril; Female; Follow-Up Studies | 1996 |
Lack of effect of orlistat on the bioavailability of a single dose of nifedipine extended-release tablets (Procardia XL) in healthy volunteers.
Topics: Administration, Oral; Adult; Analysis of Variance; Biological Availability; Calcium Channel Blockers | 1996 |
Calcium channel blockers versus ACE inhibitors as antihypertensives in polycystic kidney disease.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 1996 |
Greater reduction of urinary albumin excretion in hypertensive type II diabetic patients with incipient nephropathy by lisinopril than by nifedipine.
Topics: Adolescent; Adult; Aged; Albuminuria; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blin | 1996 |
Influence of renal failure on cytochrome P450 activity in hypertensive patients using a "cocktail" of antipyrine and nifedipine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Antipyrine; Biotransformati | 1996 |
Blood pressure and progression of renal failure in the elderly.
Topics: Aged; Aged, 80 and over; Aging; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; B | 1996 |
Renal hemodynamics in hypertensive renal allograft recipients: effects of calcium antagonists and ACE inhibitors.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Female; G | 1996 |
Treatment of hypertensive venous leg ulcers with nifedipine.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Leg Ulcer; Male; Mid | 1995 |
Trough:peak ratio of nifedipine gastrointestinal therapeutic system and nifedipine retard in essential hypertensive patients: an Italian multicentre study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Fema | 1996 |
Intraplatelet free calcium and calcium-regulating hormones in plasma are not related to the antihypertensive effect of nifedipine in hypertensive pregnancy.
Topics: Adult; Blood Platelets; Calcium; Calcium Channel Blockers; Contraceptive Agents; Female; Humans; Hyd | 1995 |
Comparison of nifedipine GITS and hydrochlorothiazide in the management of elderly patients with stage I-III diastolic hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Volume; Calcium Channel Bloc | 1996 |
Comparisons of long-term effects of lisinopril vs nifedipine vs conventional therapy in the treatment of mild-to-moderate hypertension in patients with chronic obstructive pulmonary disease.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Female; Humans; Hypertensi | 1996 |
Nifedipine and captopril exert divergent effects on heart rate variability in patients with acute episodes of hypertension.
Topics: Acute Disease; Administration, Sublingual; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Em | 1996 |
Nifedipine reduces thromboxane A2 production by platelets without changing aggregation in hypertensive pregnancy.
Topics: Adult; Antihypertensive Agents; Blood Platelets; Blood Pressure; Female; Humans; Hypertension; In Vi | 1996 |
Treatment of hypertension associated with stable angina pectoris: favourable interaction between new metoprolol formulation (OROS) and nifedipine.
Topics: Angina Pectoris; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blo | 1996 |
Effect of alpha-adrenergic blockers, ACE inhibitors, and calcium channel antagonists on renal function in hypertensive non-insulin-dependent diabetic patients.
Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood | 1996 |
INSIGHT: international nifedipine GITS study intervention as a goal in hypertension treatment.
Topics: Aged; Aged, 80 and over; Amiloride; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics | 1996 |
Effect of the lipase inhibitor orlistat on the pharmacokinetics of four different antihypertensive drugs in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 1996 |
Shanghai trial of nifedipine in the elderly (STONE).
Topics: Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Cerebrovascular Disorders; Cohort Studies; Hum | 1996 |
Structure and function of resistance arteries of hypertensive patients treated with a beta-blocker or a calcium channel antagonist.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Arteries; Atenolol; Calcium Channel Blockers; Female; Huma | 1996 |
[Comparative antihypertensive action of 20 mg delayed-action nifedipine with either 25 or 50 mg atenolol. A study on the treatment of patients with mild to moderately severe arterial hypertension].
Topics: Aged; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Delayed-Action Preparations; Dose | 1996 |
[Multicenter comparative study of felodipine-ER and nifedipine-OROS in the treatment of mild-to-moderate arterial hypertension].
Topics: Adult; Aged; Analysis of Variance; Chi-Square Distribution; Drug Tolerance; Felodipine; Female; Hear | 1996 |
A comparison of the effect of enalapril and metoprolol on renal function, potassium balance, lipid profile, cardiac function, exercise tolerance and quality of life in hypertensive dialysis patients.
Topics: Adult; Anemia; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Cell Count; | 1995 |
The antihypertensive efficacy of the novel calcium antagonist mibefradil in comparison with nifedipine GITS in moderate to severe hypertensives with ambulatory hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel B | 1997 |
Calcium antagonists, a useful additional therapy in treatment resistant hypertension: comparison of felodipine ER and nifedipine Retard by 24-h ambulatory blood pressure monitoring.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double | 1997 |
Calcium channel blockers blunt postural cutaneous vasoconstriction in hypertensive patients.
Topics: Adult; Aged; Calcium Channel Blockers; Cross-Over Studies; Female; Foot; Humans; Hypertension; Laser | 1997 |
Relation between exercise-induced left ventricular wall motion abnormalities and coronary artery disease in hypertensive patients: effects of blood pressure normalization.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Echocardiogr | 1997 |
Effectiveness of a manually controlled infusion scheme of propofol and alfentanil mixture for endotracheal intubation in hypertensive patients: in comparison with thiamylal and nifedipine plus thiamylal.
Topics: Aged; Alfentanil; Anesthetics, Intravenous; Blood Pressure; Female; Heart Rate; Humans; Hypertension | 1996 |
Effects of nifedipine and enalapril on cardiac autonomic nervous function during the tilt test in elderly patients with hypertension.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous System; Blood P | 1997 |
Predictors of the progression of diabetic nephropathy and the beneficial effect of angiotensin-converting enzyme inhibitors in NIDDM patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 1997 |
Benidipine counteracts sodium-induced alterations in systemic and regional hemodynamics.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydro | 1997 |
Effects of nifedipine and nicardipine on regional cerebral blood flow distribution in patients with arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; | 1996 |
Patient compliance and therapeutic coverage: amlodipine versus nifedipine SR in the treatment of hypertension and angina: interim results. Steering Committee and Cardiologists and General Practitioners involved in the Belgium Multicentre Study on Patient
Topics: Amlodipine; Angina Pectoris; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Patient Co | 1994 |
Nifedipine interaction with tacrolimus in liver transplant recipients.
Topics: Adult; Aged; Calcium Channel Blockers; Creatinine; Drug Interactions; Female; Humans; Hypertension; | 1997 |
Nilvadipine in hypertension--experience in ambulatory treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Blood Pressure; Calcium Channel Blocker | 1997 |
Safety of nifedipine in patients with hypertension: a meta-analysis.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Cross-Over Studies; Diuretics; D | 1997 |
Endothelin-1-induced vasopressor responses in essential hypertension.
Topics: Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc | 1997 |
Regression of nifedipine-induced gingival hyperplasia following switch to a same class calcium channel blocker, isradipine.
Topics: Adult; Aged; Antihypertensive Agents; Biopsy; Calcium Channel Blockers; Dental Plaque Index; Evaluat | 1997 |
Intravenous infusions of nifedipine: an alternative for the prevention of hypertension in eye surgery under local anesthesia.
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Blood Pressure; Calcium Channel Blockers; Double-Blind M | 1997 |
Nifedipine, captopril, metoprolol and nifedipine with metoprolol in hypertensive crisis in non-intensive care setting.
Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Captopril; Cost-Ben | 1996 |
Mibefradil in the treatment of systemic hypertension: comparative studies with other calcium antagonists.
Topics: Adult; Aged; Amlodipine; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; E | 1997 |
Safety of mibefradil, a new once-a-day, selective T-type calcium channel antagonist.
Topics: Aged; Amlodipine; Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Chronic Disease; Drug A | 1997 |
Chronic hemorheological effects of the calcium antagonist nilvadipine in essential hypertension.
Topics: Blood Pressure; Blood Viscosity; Calcium Channel Blockers; Chronic Disease; Female; Hematocrit; Huma | 1997 |
Quality of life comparison between bisoprolol and nifedipine retard in hypertension.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bisoprolol; Blood Pre | 1997 |
Efficacy of captopril and nifedipine in black and white patients with hypertensive crisis.
Topics: Administration, Oral; Adult; Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; | 1997 |
Evaluation of two forms of sustained release nifedipine using 24 h ambulatory blood pressure monitoring.
Topics: Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Delayed-Action Prep | 1997 |
[The Multicenter Captopril and the Quality of Life Study: the effect of antihypertensive agents from the basic groups on the quality of life of patients in different populations. The working group of the Multicenter Captopril and the Quality of Life Study
Topics: Antihypertensive Agents; Azerbaijan; Captopril; Demography; Humans; Hydrochlorothiazide; Hypertensio | 1996 |
[Nifedipine in the treatment of moderate and severe arterial hypertension. Long-term effect on arterial pressure and on the left ventricle].
Topics: Adult; Aged; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; Hypertensio | 1997 |
Na+/Li+ and Na+/H+ countertransport activity in hypertensive non-insulin-dependent diabetic patients: role of insulin resistance and antihypertensive treatment.
Topics: Adult; Antihypertensive Agents; Antiporters; Blood Pressure; Captopril; Diabetes Mellitus, Type 2; D | 1997 |
Efficacy of a low dose nifedipine GITS (20 mg) in patients with mild to moderate hypertension.
Topics: Adult; Antihypertensive Agents; Digestive System; Female; Humans; Hypertension; Male; Middle Aged; N | 1997 |
[Comparative study to assess the efficacy and adverse effects of amlodipine and nifedipine retard in patients with stable exertional angina and hypertension].
Topics: Aged; Amlodipine; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Drug Administration Sch | 1997 |
The effects of long-term treatment on left ventricular hypertrophy in patients with essential hypertension: relation to changes in neurohumoral factors.
Topics: Adult; Aged; Aldosterone; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atrial | 1997 |
Equivalent reduction of proteinuria in hypertensives by either nifedipine GITS or enalapril: disparate effects on neurohormones and ambulatory blood pressure and the influence of salt.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Blood Pressure Monitoring, Ambulator | 1997 |
Effects of antihypertensive agents on circadian blood pressure in hypertensive patients with previous brain infarction.
Topics: Acebutolol; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Ca | 1997 |
Twenty-four-hour blood pressure monitoring during treatment with extended-release felodipine versus slow-release nifedipine in elderly patients with mild to moderate hypertension: a randomized, double-blind, cross-over study.
Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bloc | 1997 |
[The effect of nifedipine on peroxidation and some antioxidant factors in polymorphonuclear granulocytes of peripheral blood].
Topics: Adolescent; Adult; Child; Child, Preschool; Glutathione Peroxidase; Humans; Hypertension; Lipid Pero | 1997 |
Nifedipine-retard versus nifedipine-capsules for the therapy of hypertensive crisis in black patients.
Topics: Administration, Oral; Adult; Black People; Blood Pressure; Delayed-Action Preparations; Double-Blind | 1998 |
Differential properties of mibefradil in hypertension and angina.
Topics: Angina Pectoris; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Heart Rat | 1997 |
Comparison of effects of controlled onset extended release verapamil at bedtime and nifedipine gastrointestinal therapeutic system on arising on early morning blood pressure, heart rate, and the heart rate-blood pressure product.
Topics: Analysis of Variance; Blood Pressure; Chronotherapy; Delayed-Action Preparations; Double-Blind Metho | 1998 |
The natriuretic effect of nifedipine gastrointestinal therapeutic system remains despite the presence of mild-to-moderate renal failure.
Topics: Administration, Oral; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium | 1997 |
Barnidipine, a novel calcium antagonist for once-daily treatment of hypertension: a multicenter, double-blind, placebo-controlled, dose-ranging study. Dutch Barnidipine Multicenter Study Group.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Edema; Female; Flushing; He | 1997 |
The addition of a diuretic to anti-hypertensive therapy for early severe hypertension in pregnancy.
Topics: Adult; Amiloride; Antihypertensive Agents; Diuretics; Drug Combinations; Drug Therapy, Combination; | 1998 |
[The effect of short term administration of cordafen on lipid peroxidation, activity of certain antioxidant enzymes and levels of reduced glutathione in erythrocytes].
Topics: Administration, Oral; Adult; Calcium Channel Blockers; Drug Administration Schedule; Erythrocytes; G | 1997 |
Effect of hypotensive drugs on the circadian blood pressure pattern in essential hypertension: a comparative study.
Topics: Adrenergic beta-Antagonists; Aged; Amiloride; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 1997 |
Evaluation of changes in sympathetic nerve activity and heart rate in essential hypertensive patients induced by amlodipine and nifedipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Circadia | 1998 |
A comparison of the safety and efficacy of mibefradil and nifedipine SR in patients with renal disease and hypertension.
Topics: Adult; Aged; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; | 1998 |
Compliance and antihypertensive efficacy of amlodipine compared with nifedipine slow-release.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitor | 1998 |
Comparative effects of felodipine ER, amlodipine and nifedipine GITS on 24 h blood pressure control and trough to peak ratios in mild to moderate ambulatory hypertension: a forced titration study.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bloc | 1998 |
A randomised crossover comparison of reserpine and sustained-release nifedipine in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Delayed-Action Preparation | 1997 |
Nifedipine and cancer mortality: ten-year follow-up of 2607 patients after acute myocardial infarction.
Topics: Aged; Calcium Channel Blockers; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; | 1998 |
Distinct vasodilation, without reflex neurohormonal activation, induced by barnidipine in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Femal | 1998 |
Nifedipine versus expectant management in mild to moderate hypertension in pregnancy. Gruppo di Studio Ipertensione in Gravidanza.
Topics: Adult; Birth Weight; Calcium Channel Blockers; Delayed-Action Preparations; Female; Gestational Age; | 1998 |
A comparison of the antihypertensive efficacy and safety of felodipine IV and nifedipine IV in patients with hypertensive crisis or emergency not responding to oral nifedipine.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Emergencies; Fel | 1998 |
DA1-receptor stimulation by fenoldopam in the treatment of postcardiac surgical hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Catheterization, | 1998 |
Comparison of 24-hour blood pressure, heart rate, and autonomic nerve activity in hypertensive patients treated with cilnidipine or nifedipine retard.
Topics: Autonomic Pathways; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dihydropyridines; | 1998 |
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Epinephrin | 1998 |
Regression of left ventricular hypertrophy in hypertensive patients after 1 year of treatment with rilmenidine: a double-blind, randomized, controlled (versus nifedipine) study.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diastole; Double-Blind Met | 1998 |
Reduction of cardiovascular structural changes by nifedipine GITS in essential hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepa | 1998 |
Captopril, but not nifedipine, improves endothelium-dependent vasodilation in hypertensive patients.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arteries; Calcium Channel Blockers; Captopril; Doubl | 1998 |
Comparative efficacies of a calcium antagonist and an alpha1 blocker in elderly hypertensive patients with stroke.
Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Aging; Blood Pressure Monitoring, Ambulatory; | 1998 |
[Clinical study on combined treatment of shuizhi tuyuan powder and nifedipine in treating hypertension patients complicated with left ventricular hypertrophy].
Topics: Adult; Aged; Animals; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertens | 1996 |
Comparison of the efficacy of dihydropyridine calcium channel blockers in African American patients with hypertension. ISHIB Investigators Group. International Society on Hypertension in Blacks.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Black People; Blood Pressure; Body Weight; Calcium | 1998 |
Renal and haemodynamic effects of amlodipine and nifedipine in hypertensive renal transplant recipients.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; C | 1998 |
A study of losartan, alone or with hydrochlorothiazide vs nifedipine GITS in elderly patients with diastolic hypertension.
Topics: Aged; Aging; Antihypertensive Agents; Calcium Channel Blockers; Diastole; Double-Blind Method; Drug | 1998 |
The International Nifedipine GITS Study of Intervention as a Goal in Hypertension Treatment (INSIGHT) trial.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic | 1998 |
Steady-state trough plasma mibefradil concentrations and correlation to blood pressure response in hypertensive patients with chronic renal disease.
Topics: Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dose | 1998 |
Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Administration Schedule; | 1998 |
Abnormal sonographic endometrial findings in asymptomatic postmenopausal women: possible role of antihypertensive drugs.
Topics: Aged; Antihypertensive Agents; Atrophy; Biopsy; Calcium Channel Blockers; Endometrium; Female; Human | 1998 |
Study population and treatment titration in the International Nifedipine GITS Study: Intervention as a Goal in Hypertension Treatment (INSIGHT).
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiova | 1998 |
Long-term efficacy and adverse event of nifedipine sustained-release tablets for cyclosporin A-induced hypertension in patients with psoriasis.
Topics: Adult; Aged; Blood Pressure Determination; Calcium Channel Blockers; Cyclosporine; Delayed-Action Pr | 1998 |
Contrasting effects of vasodilators on blood pressure and sodium balance in the hypertension of autonomic failure.
Topics: Aged; Autonomic Nervous System; Blood Pressure; Circadian Rhythm; Female; Heart Rate; Humans; Hypert | 1999 |
Divergent effects of ACE-inhibition and calcium channel blockade on NO-activity in systemic and renal circulation in essential hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiac Output; Dose-Resp | 1998 |
A perspective on the calcium antagonists in blacks (CAB) trial.
Topics: Amlodipine; Antihypertensive Agents; Black or African American; Blood Pressure; Blood Pressure Monit | 1998 |
A randomised double-blind study comparing nifedipine GITS 20 mg and bendrofluazide 2.5 mg administered once daily in mild-to-moderate hypertension.
Topics: Aged; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; | 1999 |
Effect of treatment on flow-dependent vasodilation of the brachial artery in essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Arm; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Br | 1999 |
Evaluation of amlodipine dosing for conversion of nifedipine extended-release to amlodipine in the treatment of hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparati | 1999 |
Long-acting lacidipine versus short-acting nifedipine in the treatment of asymptomatic acute blood pressure increase.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure | 1999 |
Reduced bcl-2 concentrations in hypertensive patients after lisinopril or nifedipine administration.
Topics: Administration, Oral; Antihypertensive Agents; Apoptosis; Arteries; Biomarkers; Blood Pressure; Cell | 1999 |
[The additional efficacy of the nifedipine-diuretic combination depends on the potency of the drug administered first and not the sequence of administration. A double blind study in salt-sensitive black hypertensives].
Topics: Adult; Antihypertensive Agents; Black People; Calcium Channel Blockers; Cross-Over Studies; Diuretic | 1999 |
Nebivolol versus nifedipine in the treatment of essential hypertension: a double-blind, randomized, comparative trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzopyrans; Blood Pressure; Calc | 1998 |
Baroreflex sensitivity changes with calcium antagonist therapy in elderly subjects with isolated systolic hypertension.
Topics: Age Factors; Aged; Baroreflex; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cros | 1999 |
Systolic Hypertension in Europe (Syst-Eur) trial phase 2: objectives, protocol, and initial progress. Systolic Hypertension in Europe Investigators.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Bloc | 1999 |
Controlled study of the effect of angiotensin converting enzyme inhibition versus calcium-entry blockade on insulin sensitivity in overweight hypertensive patients: Trandolapril Italian Study (TRIS).
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Blood Pressure; Calcium; | 1999 |
Ambulatory blood pressure profiles in essential hypertensives after treatment with a new once daily nifedipine formulation.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circad | 1999 |
Physical Symptoms Distress Index: a sensitive tool to evaluate the impact of pharmacological agents on quality of life.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Constipation; Dou | 1999 |
[Effect of antihypertensive agents on plasma endothelin, nitric oxide and so on in essential hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agent | 1997 |
Comparison between isosorbide dinitrate aerosol and nifedipine in the treatment of hypertensive emergencies.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Electrocardiography; Emergency Medical Services; Fe | 1999 |
Control of vascular tone in isolated mesenteric arterial segments from hypertensive patients.
Topics: Adult; Aged; Aged, 80 and over; Calcimycin; Calcium Channel Blockers; Endothelium, Vascular; Enzyme | 1999 |
Cilnidipine, the N- and L-type calcium channel antagonist, reduced on 24-h urinary catecholamines and C-peptide in hypertensive non-insulin-dependent diabetes mellitus.
Topics: Aged; C-Peptide; Calcium Channel Blockers; Catecholamines; Chromatography, High Pressure Liquid; Cro | 1999 |
24-hour ambulatory blood pressure monitoring: a comparison between transdermal glyceryl-trinitrate and oral nifedipine.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Analysis of Variance; Female; Humans; Hypert | 1999 |
Acute hypotensive, natriuretic, and hormonal effects of nifedipine in salt-sensitive and salt-resistant black normotensive and hypertensive subjects.
Topics: Adult; Aldosterone; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; | 1999 |
Therapeutic approach to patients complaining of high blood pressure in a cardiological emergency room.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Captopril; Coronary Care Units; Emergency Medical | 1999 |
A randomized, double-blind trial of oral nifedipine and intravenous labetalol in hypertensive emergencies of pregnancy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; | 1999 |
A randomized, double-blind, hemodynamic evaluation of nifedipine and labetalol in preeclamptic hypertensive emergencies.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; E | 1999 |
Sex difference in response of blood pressure to calcium antagonism in the treatment of moderate-to-severe hypertension.
Topics: Blood Pressure; Calcium Channel Blockers; Diastole; Female; Humans; Hypertension; Male; Nifedipine; | 1999 |
Cross-over comparison of nifedipine Oros and felodipine extended release with blind 24 h ambulatory blood pressure assessments.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; | 1999 |
Use of calcium-channel blockers in pediatric renal transplant recipients.
Topics: Adolescent; Amlodipine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Drug Therapy, | 1999 |
[24-hour blood pressure monitoring in diagnosis and therapy of arterial hypertension].
Topics: Adult; Aged; Blood Pressure Monitors; Calcium Channel Blockers; Female; Humans; Hypertension; Male; | 1999 |
Comparative study of nifedipine CD retard 30 tablets vs enalapril in patients of uncomplicated essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Delayed-Action Preparations; Enalapril; Female; Humans; Hypert | 1999 |
Bisoprolol and nifedipine retard in elderly hypertensive patients: effect on quality of life.
Topics: Adrenergic beta-Agonists; Affect; Aged; Aging; Antihypertensive Agents; Bisoprolol; Calcium Channel | 2000 |
Cardiovascular effects of melatonin in hypertensive patients well controlled by nifedipine: a 24-hour study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Drug | 2000 |
Medical therapy, symptoms, and the distress the cause: relation to quality of life in patients with angina pectoris and/or hypertension.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Amlodipine; Angina Pectoris | 2000 |
Nifedipine or prazosin as a second agent to control early severe hypertension in pregnancy: a randomised controlled trial.
Topics: Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypertension; Ni | 2000 |
Nifedipine administered in pregnancy: effect on the development of children at 18 months.
Topics: Calcium Channel Blockers; Child Development; Female; Follow-Up Studies; Humans; Hypertension; Infant | 2000 |
Effect of lacidipine and nifedipine GITS on platelet function in patients with essential hypertension.
Topics: Arachidonic Acid; Biomarkers; Blood Platelets; Blood Pressure; Calcium Channels; Dihydropyridines; F | 2000 |
Natriuretic effect of barnidipine, a long-acting dihydropyridine calcium channel blocker, in patients with essential hypertension.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis; | 2000 |
Effect of enalapril and nifedipine on orthostatic hypotension in older hypertensive patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel B | 2000 |
[The effect of amlodipine, nifedipine and perindopril on insulin sensitivity and blood lipid of patients with essential hypertension].
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Insulin | 1998 |
Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT).
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Calcium Channel Blockers; Chemistry, Ph | 2000 |
[Comparative study of diuretics in hypertensive patients. Calcium antagonist also improves prognosis].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Humans; Hypertension; Nifedi | 2000 |
A randomized prospective crossover trial of amlodipine in pediatric hypertension.
Topics: Adolescent; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulato | 2000 |
Underestimation of 24-hour hypotensive efficacy of nifedipine GITS versus enalapril: ambulatory recording as an adjunct to clinical blood pressure measurement.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Double-Blind Met | 2000 |
[Osmo-adalat in the treatment of isolated systolic and systolic-diastolic arterial hypertension in aged patients].
Topics: Age Factors; Aged; Calcium Channel Blockers; Circadian Rhythm; Diastole; Female; Humans; Hypertensio | 2000 |
Comparison of efficacy and side effects of combination therapy of angiotensin-converting enzyme inhibitor (benazepril) with calcium antagonist (either nifedipine or amlodipine) versus high-dose calcium antagonist monotherapy for systemic hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Be | 2000 |
Effects of short- and long-acting calcium channel blockers on the relationship between blood pressure and physical activity.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circad | 2001 |
Comparative effects of mibefradil and nifedipine gastrointestinal transport system on autonomic function in patients with mild to moderate essential hypertension.
Topics: Autonomic Nervous System; Calcium Channel Blockers; Double-Blind Method; Electrocardiography; Female | 2001 |
Blood pressure control in patients with mild to moderate essential hypertension switched from nifedipine gastrointestinal therapeutic system (GITS) 30 mg to nifedipine GITS 20 mg.
Topics: Aged; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 2001 |
Treatment of hypertension in the very old.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 2000 |
The long-term efficacy and safety profile of barnidipine.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combinatio | 2000 |
Barnidipine monotherapy and combination therapy in older patients with essential hypertension: a long-term study.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel B | 2000 |
Are there any relevant differences within the calcium antagonist class?
Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Humans; Hype | 2000 |
Effect of prazosin GITS, atenolol, nifedipine SR, and enalapril on ADP-induced platelet aggregation.
Topics: Adenosine Diphosphate; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Angiotensin | 1998 |
Prazosin GITS vs sustained release nifedipine in patients with hypertension and abnormal lipid profile: a randomized, controlled, multicenter study. Madras Hypertension Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Delayed-Action Preparations; Female; Heart Rate; Humans; Hyper | 1998 |
Comparison of two calcium blockers on hemodynamics, left ventricular mass, and coronary vasodilatory in advanced hypertension.
Topics: Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Coronary Vessels; Diastole; Echocard | 2001 |
Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black Pe | 2001 |
Effect of acute blood pressure reduction on endothelial function in the brachial artery of patients with essential hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Brachial A | 2001 |
Evaluation of the method for nifedipine administration for a rapid onset of clinical effect: a clinical study in normal volunteers.
Topics: Administration, Intranasal; Administration, Oral; Administration, Sublingual; Adult; Blood Pressure; | 2001 |
Calcium channel blocker nifedipine slows down progression of coronary calcification in hypertensive patients compared with diuretics.
Topics: Aged; Amiloride; Calcinosis; Calcium Channel Blockers; Cardiomyopathies; Coronary Artery Disease; Di | 2001 |
Differential effects of nifedipine and co-amilozide on the progression of early carotid wall changes.
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Atenolol; Blood Pressure; Carotid Arter | 2001 |
Better microvascular function on long-term treatment with lisinopril than with nifedipine in renal transplant recipients.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Blood Pressure; Calcium Channel B | 2001 |
Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma.
Topics: Adult; Aged; Antihypertensive Agents; Asthma; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Br | 2001 |
Reduction of left ventricular mass by lisinopril and nifedipine in hypertensive renal transplant recipients: a prospective randomized double-blind study.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Cyclosporine; Delayed-Action Preparations; | 2001 |
A single (investigator)-blind randomised control trial comparing the effects of quinapril and nifedipine on platelet function in patients with mild to moderate hypertension.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; beta-Thromboglobulin; Blood Platelets; Blood Pressu | 2001 |
Blood pressure reduction and tolerability of amlodipine versus nifedipine retard in Chinese patients with type 2 diabetes mellitus and hypertension: a randomized 1-year clinical trial.
Topics: Administration, Oral; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, | 2001 |
Bisoprolol and nifedipine SR in the treatment of hypertension in the elderly.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Bisoprolol; Blood Pressure; Calcium Channel Bl | 1990 |
Effects of once-daily angiotensin-converting enzyme inhibition and calcium channel blockade-based antihypertensive treatment regimens on left ventricular hypertrophy and diastolic filling in hypertension: the prospective randomized enalapril study evaluat
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Diastole; | 2001 |
Effective blood pressure treatment improves LDL-cholesterol susceptibility to oxidation in patients with essential hypertension.
Topics: Adult; Antihypertensive Agents; Atenolol; Cholesterol, LDL; Double-Blind Method; Drug Therapy, Combi | 2001 |
A random comparison of fosinopril and nifedipine GITS in patients with primary renal disease.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Del | 2001 |
[Efficacy of OSMO-Adalat in patients with arterial hypertension in combination with kinked precerebral arteries].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Carotid Artery Diseases; De | 2001 |
Influence of the angiotensin II receptor antagonist losartan on diuretic-induced metabolic effects in elderly hypertensive patients: comparison with a calcium channel blocker.
Topics: Aged; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blo | 2001 |
Efficacy, tolerability and influence on "quality of life" of nifedipine GITS versus amlodipine in elderly patients with mild-moderate hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; | 2001 |
Nifedipine and enalapril equally reduce the progression of nephropathy in hypertensive type 2 diabetics.
Topics: Albuminuria; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Disea | 2001 |
Efficacy of nifedipine or lisinopril in the treatment of hypertension after renal transplantation: a double-blind randomised comparative trial.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Female; Humans; Hypertension; Kidney Transplant | 2001 |
Sustained improvement of renal graft function for two years in hypertensive renal transplant recipients treated with nifedipine as compared to lisinopril.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hyper | 2001 |
[Changes in blood rheological properties in patients with hypertension].
Topics: Adrenergic beta-Antagonists; Blood; Blood Viscosity; Calcium Channel Blockers; Diuretics; Drug Thera | 2001 |
[The effect of Nifedipine on postpartum blood loss in patients with pregnancy induced hypertension].
Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Nifedipine; Postpartum Hemorrhage; Pregnancy | 2000 |
[Greater reduction of urinary albumin excretion in hypertensive patients with perindopril than nifedipine].
Topics: Adult; Aged; Albuminuria; Antihypertensive Agents; Blood Pressure; Female; Glomerular Filtration Rat | 1999 |
Persistence of antihypertensive efficacy after missed doses: comparison of amlodipine and nifedipine gastrointestinal therapeutic system.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studi | 2002 |
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Cha | 2002 |
[The novel method for selection of preparations for treatment of arterial hypertension based on spectral analysis of heart rhythm variability].
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aten | 2001 |
Twenty-four hour ambulatory blood pressure in the International Nifedipine GITS Study Intervention as a Goal in Hypertension Treatment (INSIGHT).
Topics: Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Blood Pressure Determination; Blood Pre | 2002 |
Factors related to the occurrence of microalbuminuria during antihypertensive treatment in essential hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Antihyper | 2002 |
Effects of chronic calcium channel blockade on sympathetic nerve activity in hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepar | 2002 |
Efficacy and safety of two different formulations of nifedipine (GITS) vs. slow release microgranules in patients with mild and moderate hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Double-Blind Method; F | 2002 |
A comparative crossover evaluation of amlodipine and nifedipine GITS before and after a missed dose: 48-h blood pressure profiles.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Digestive | 2002 |
Prospective controlled trial of two nifedipine extended release formulations in the treatment of essential hypertension.
Topics: Adolescent; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Calcium | 2002 |
Haemodynamic effects of a calcium antagonistic agent (nifedipine) in hypertension: therapeutic implications.
Topics: Hemodynamics; Humans; Hypertension; Middle Aged; Nifedipine; Pyridines | 1978 |
Treatment of hypertension with nifedipine, a calcium antagonistic agent.
Topics: Administration, Oral; Blood Pressure; Calcium; Chemical Phenomena; Chemistry; Clinical Trials as Top | 1979 |
[On the clinical evaluation of therapy with nifedipine in association with various anithypertensive drugs (author's transl)].
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Drug Evaluation; Drug Synergi | 1977 |
24-hour blood pressure control after single daily doses of nivaldipine in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Administration | 1992 |
Comparison of the efficacy of nilvadipine and nitrendipine on circadian blood pressure.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Double-Blind Method; Drug Administration | 1992 |
The tolerability of nilvadipine compared to nifedipine in patients with essential hypertension.
Topics: Alanine Transaminase; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Tolerance; | 1992 |
Comparisons of once-daily nilvadipine with enalapril and diuretic in patients with essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Administration Schedule; Drug The | 1992 |
Antihypertensive drug effects on placental flow velocity waveforms in pregnant women with severe hypertension.
Topics: Arteries; Blood Flow Velocity; Double-Blind Method; Female; Humans; Hydralazine; Hypertension; Nifed | 1992 |
[Comparative hypotensive effectiveness of various calcium antagonists in patients with persistent essential hypertension (randomized study)].
Topics: Blood Pressure; Calcium Channel Blockers; Chronic Disease; Dihydropyridines; Diltiazem; Dose-Respons | 1992 |
[A prospective study on the effect of nifedipine of the cardiovascular complications in the elderly hypertensives].
Topics: Aged; Angina Pectoris; Arrhythmias, Cardiac; Cerebrovascular Disorders; Female; Humans; Hypertension | 1992 |
Lisinopril and nifedipine administration inhibits the ex vivo uptake of [45Ca2+] by platelets from hypertensive diabetic patients.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Platelets; Bucladesine; Calcium; Diabet | 1992 |
Evaluation of the antihypertensive effect of lisinopril compared with nifedipine in patients with mild to severe essential hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Female; Humans; Hypertensio | 1992 |
A comparative trial of lisinopril and nifedipine in mild to moderate hypertension in general practice.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bias; Enalapril; Family Practice; Female; H | 1992 |
[Cough during treatment with angiotensin-converting enzyme inhibitors is gender related].
Topics: Angiotensin-Converting Enzyme Inhibitors; Cough; Dipeptides; Double-Blind Method; Drug Evaluation; F | 1992 |
[Treatment with lisinopril or nifedipine in essential hypertension. A Norwegian multicenter study of the effect, tolerance and quality of life of 828 patients].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Cough; Dipeptides; Double-Blind Method; Femal | 1992 |
[Comparison of nicardipine and nifedipine in treatment of Chinese senile hypertension placebo-control, double-blind, randomized and crossover study].
Topics: Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Nicardip | 1992 |
Hemodynamic effects of isradipine and nifedipine in chronic sustained hypertension.
Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Hemodynamics; Humans; Hypertension; Infusions, Int | 1992 |
New sustained-release nifedipine formulation in treatment of essential hypertension. Unidipin Cooperative Study Group.
Topics: Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Fema | 1992 |
Safety of the coadministration of carvedilol and nifedipine sustained-release in the treatment of essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; Del | 1992 |
Comparison of the effects of carvedilol and nifedipine in patients with essential hypertension and non-insulin-dependent diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Carbazoles; Carvedilol; | 1992 |
Comparison of the effect of celiprolol and nifedipine on blood pressure and plasma lipids.
Topics: Acyltransferases; Adult; Antihypertensive Agents; Apoproteins; Blood Pressure; Celiprolol; Cholester | 1992 |
Quality of life on antihypertensive therapy: a double-blind trial comparing quality of life on pinacidil and nifedipine in combination with a thiazide diuretic. European Pinacidil Study Group.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Data Interpre | 1992 |
[Effect of nilvadipine on diurnal blood pressure profile. Use of a new calcium channel blocker in mild to intermediate hypertension].
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Female; Humans; Hypertensio | 1992 |
[The efficacy of nitrendipine in patients with stable arterial hypertension. The data from a cooperative study in the USSR. The Working Group for the Cooperative Study of Nitrendipine].
Topics: Adult; Chi-Square Distribution; Drug Tolerance; Humans; Hydrochlorothiazide; Hypertension; Lipids; M | 1992 |
Comparison of enalapril and nifedipine in treating non-insulin dependent diabetes associated with hypertension: one year analysis.
Topics: Albuminuria; Blood Pressure; Body Weight; Diabetes Mellitus, Type 2; Double-Blind Method; Enalapril; | 1992 |
Intravenous nifedipine for prevention of myocardial ischaemia after coronary revascularization.
Topics: Blood Pressure; Coronary Artery Bypass; Creatine Kinase; Electrocardiography; Electrocardiography, A | 1992 |
Comparison of nitroglycerin with nifedipine in patients with hypertensive crisis or severe hypertension.
Topics: Acute Disease; Aged; Aged, 80 and over; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Ma | 1992 |
Serum concentration-effect relationship of (+/-)-nicardipine and nifedipine in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Fema | 1992 |
[Effects of furosemide, propranolol and nifedipine on urinary excretion of Tamm-Horsfall protein in patients with arterial hypertension].
Topics: Adult; Circadian Rhythm; Female; Furosemide; Humans; Hypertension; Male; Middle Aged; Mucoproteins; | 1992 |
Peritoneal clearances in hypertensive CAPD patients after oral administration of clonidine, enalapril, and nifedipine.
Topics: Biological Transport; Clonidine; Enalapril; Female; Humans; Hypertension; Kidney Failure, Chronic; M | 1992 |
A comparison of the acute hypotensive effects of two different doses of nifedipine.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Hypertensio | 1992 |
Double-blind comparison of captopril with nifedipine in hypertension complicated by intermittent claudication.
Topics: Blood Pressure; Captopril; Double-Blind Method; Exercise Test; Female; Humans; Hypertension; Intermi | 1992 |
[Skin blood flow and veno-arteriolar response in essential hypertension].
Topics: Adult; Female; Humans; Hypertension; Leg; Male; Microcirculation; Middle Aged; Nifedipine; Rest; Ski | 1992 |
[Effectiveness and tolerance of amlodipine in treatment of patients with mild to moderate hypertension. Results of a long-term study with a new calcium antagonist].
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Drug Evaluation; Female; Humans; | 1992 |
[A comparison between amlodipine and nifedipine retard in patients with essential arterial hypertension].
Topics: Adult; Aged; Amlodipine; Analysis of Variance; Calcium Channel Blockers; Delayed-Action Preparations | 1992 |
Quality of life with three antihypertensive treatments. Cilazapril, atenolol, nifedipine.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Cilazap | 1992 |
Amlodipine compared to nitrendipine in hypertensive patients: the effects on toleration in relationship to the onset of action.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; | 1992 |
Comparison of early side effects with amlodipine and nifedipine retard in hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocke | 1992 |
Changes in left ventricular dimensions and systolic function in 100 mildly hypertensive men during one year's treatment with atenolol vs. hydrochlorothiazide and amiloride (Moduretic): a double-blind, randomized study.
Topics: Adult; Aged; Atenolol; Cardiomegaly; Double-Blind Method; Echocardiography; Humans; Hydrochlorothiaz | 1992 |
[Nifedipine versus nitroglycerin in aortocoronary bypass surgery. The effect on hemodynamics, kidney function and homologous blood requirement].
Topics: Adult; Aged; Blood Transfusion; Coronary Artery Bypass; Female; Hemodynamics; Humans; Hypertension; | 1992 |
Atenolol compared with nifedipine: effect on cognitive function and mood in elderly hypertensive patients.
Topics: Affect; Aged; Aged, 80 and over; Atenolol; Cognition; Double-Blind Method; Female; Humans; Hypertens | 1992 |
[24-hour blood pressure decrease with nifedipine with a new galenic action].
Topics: Adult; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Female; Humans; Hypertension; | 1992 |
Effectiveness of once-daily monotherapy with a new nifedipine sustained release calcium antagonist.
Topics: Adult; Aged; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Dru | 1992 |
Intravenous nifedipine to treat hypertension after coronary artery revascularization surgery. A comparison with sodium nitroprusside.
Topics: Blood Pressure; Coronary Artery Bypass; Coronary Disease; Creatine Kinase; Electrocardiography, Ambu | 1992 |
Exercise performance in patients with uncomplicated essential hypertension. Effects of nifedipine-induced acute blood pressure reduction.
Topics: Blood Pressure; Breath Tests; Double-Blind Method; Drug Evaluation; Exercise; Exercise Test; Humans; | 1992 |
Comparison of the effects of nilvadipine and captopril on glucose and lipid metabolism in NIDDM patients with hypertension.
Topics: Analysis of Variance; Apolipoprotein A-I; Apolipoprotein A-II; Apolipoproteins B; Blood Glucose; Blo | 1992 |
Effects of long-acting nifedipine on casual office blood pressure measurements, 24-hour ambulatory blood pressure profiles, exercise parameters and left ventricular mass and function in black patients with mild to moderate systemic hypertension.
Topics: Adult; Ambulatory Care; Black People; Blood Pressure; Blood Pressure Determination; Circadian Rhythm | 1992 |
Effects of antihypertensive therapy on human alpha- and beta-adrenoceptors.
Topics: Dihydroergotoxine; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifed | 1991 |
Lisinopril or nifedipine in essential hypertension? A Norwegian multicenter study on efficacy, tolerability and quality of life in 828 patients.
Topics: Antihypertensive Agents; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Lisinopril; M | 1991 |
Lisinopril and nifedipine in essential hypertension: a Norwegian multicenter study on efficacy, tolerability and quality of life in 828 patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Enalapril; Female; Heart | 1991 |
Interaction of citrus juices with felodipine and nifedipine.
Topics: Biological Availability; Blood Pressure; Citrus; Drug Interactions; Evaluation Studies as Topic; Fel | 1991 |
Comparison of felodipine with nifedipine as additions to metoprolol in the treatment of hypertension. U.K. Multicentre Hospital Group.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Felodipine; Heart Rate; | 1990 |
Calcium antagonists as first-line antihypertensive agents: a placebo-controlled, comparative trial of isradipine and nifedipine.
Topics: Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate; Humans; Hypertens | 1990 |
Vascular pressor responses in treated and untreated essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Blood Pressure; Catecholamines; D | 1990 |
The combination of chlorthalidone with nifedipine does not exert an additive antihypertensive effect in essential hypertensives: a crossover multicenter study.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Interactions; Drug Therapy, C | 1991 |
First clinical experience with isradipine in the treatment of hypertension in Portugal.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-B | 1991 |
A comparative study of carvedilol, slow-release nifedipine, and atenolol in the management of essential hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Carbazoles; Carvedilol; | 1991 |
Effects of nifedipine and nitrendipine on insulin secretion in obese patients.
Topics: Adult; Analysis of Variance; Blood Glucose; C-Peptide; Double-Blind Method; Female; Humans; Hyperten | 1991 |
Nifedipine vs. enalapril in treatment of hypertensive patients with glucose intolerance.
Topics: Blood Glucose; Cholesterol; Enalapril; Glucose; Humans; Hypertension; Insulin; Middle Aged; Nifedipi | 1991 |
The effects of nisoldipine, diltiazem, nifedipine, and verapamil on hemodynamic parameters and red blood cells-platelet interactions in patients with arterial hypertension.
Topics: Adult; Aged; Arteries; Blood Platelets; Blood Pressure; Calcium Channel Blockers; Diltiazem; Erythro | 1991 |
Studies of captopril alone and in combination with the benzothiazepine diltiazem or the dihydropyridine nifedipine in treating essential hypertension.
Topics: Adult; Aged; Blood Pressure; Captopril; Diltiazem; Double-Blind Method; Drug Therapy, Combination; H | 1991 |
Nifedipine improves left ventricular function in patients with hypertension.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Female; Heart Rate; Humans; Hypertension; Infusion Pump | 1991 |
Comparative study of lacidipine and nifedipine SR in the treatment of hypertension: an Italian multicenter study. The Northern Italian Study Group of Lacidipine in Hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines | 1991 |
Angiotensin converting enzyme inhibitors versus calcium antagonists in the treatment of diabetic hypertensive patients.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Creatinine; Diab | 1992 |
Sublingual nifedipine in hypertensive emergencies with special reference to cerebrovascular accident.
Topics: Administration, Sublingual; Blood Pressure; Cerebrovascular Disorders; Emergencies; Humans; Hyperten | 1991 |
[Nifedipine-clonidine combination in essential hypertension. Hemodynamic and neurohumoral findings of the combination in comparison with the effect of the individual substances].
Topics: Clonidine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hemodynamics; Humans | 1991 |
[A comparison of the effects of verapamil and nifedipine on the quality of life].
Topics: Adult; Affect; Aged; Blood Pressure; Cognition; Delayed-Action Preparations; Double-Blind Method; Fe | 1991 |
[Screening of single doses of the main antihypertensive drugs at rest and during various exercise tests in patients with hypertension].
Topics: Adult; Blood Pressure; Drug Evaluation; Exercise; Exercise Test; Humans; Hydrochlorothiazide; Hypert | 1991 |
Nicardipine and nifedipine in the treatment of essential arterial hypertension.
Topics: Adult; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Heart Rate; Humans; Hyperte | 1991 |
Nifedipine and nisoldipine in hypertensive diabetics.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Diabetes Complications; Diabetes Mellitus; Humans; Hyper | 1991 |
No adverse effect of non-steroidal anti-inflammatory drugs, sulindac and diclofenac sodium, on blood pressure control with a calcium antagonist, nifedipine, in elderly hypertensive patients.
Topics: Aged; Blood Pressure; Diclofenac; Dinoprostone; Drug Therapy, Combination; Female; Humans; Hypertens | 1991 |
[Hemodynamic response of patients with arterial hypertension to graded pedal isometric exercise after administration of vasodilators of different classes].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Drug Evaluation; Exercise Test; Female; Hemodynamic | 1991 |
The effect of enalapril and calcium antagonists on blood pressure and cerebral perfusion in elderly hypertensives.
Topics: Aged; Blood Pressure; Cerebrovascular Circulation; Enalapril; Female; Humans; Hypertension; Male; Mi | 1991 |
Metabolic effects of enalapril and nifedipine in diabetic hypertensives.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Enalapril; Glycated Hemoglobin; Humans; Hypertension; Insu | 1991 |
[Comparison of the effects of diazepam, nifedipine, propranolol and a combination of nifedipine and propranolol, by sublingual administration, in patients with hypertensive crisis].
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Diazepam; Drug Therapy, Combination; Female | 1991 |
Short-term effects of atenolol and nifedipine on atrial natriuretic peptide, plasma renin activity, and plasma aldosterone in patients with essential hypertension.
Topics: Adult; Aldosterone; Atenolol; Atrial Natriuretic Factor; Female; Humans; Hypertension; Male; Middle | 1991 |
Normalization of left ventricular mass and associated changes in neurohormones and atrial natriuretic peptide after 1 year of sustained nifedipine therapy for severe hypertension.
Topics: Atrial Natriuretic Factor; Cardiomegaly; Chlorthalidone; Delayed-Action Preparations; Echocardiograp | 1991 |
Atrial natriuretic peptide lowering effect of antihypertensives in patients with essential hypertension.
Topics: Antihypertensive Agents; Atrial Natriuretic Factor; Captopril; Humans; Hypertension; Nifedipine | 1991 |
A double-blind crossover study of the effect of concomitant diuretic therapy in hypertensive patients treated with amlodipine.
Topics: Adult; Amlodipine; Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Double-Blind Metho | 1991 |
[Therapy of mild to moderate hypertension. Efficacy and tolerance of Amlodipine in comparison with the combination nifedipine/mefruside].
Topics: Adult; Aged; Amlodipine; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hypertension; | 1991 |
Acute and sustained changes in sodium balance during nifedipine treatment in essential hypertension.
Topics: Aged; Aldosterone; Analysis of Variance; Atrial Natriuretic Factor; Blood Pressure; Delayed-Action P | 1991 |
Amlodipine: an effective once-daily antihypertensive agent.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Administration S | 1991 |
[The hemodynamic effects of isradipine and nifedipine in hypertension].
Topics: Adult; Blood Pressure; Cardiac Output; Dihydropyridines; Female; Heart; Heart Function Tests; Humans | 1991 |
A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Blood Pressure Determination; Calcium Channel B | 1991 |
A study of the efficacy and safety of amlodipine for the treatment of hypertension in general practice.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Edema; Female; Headache; Human | 1991 |
A double-blind, parallel, comparative evaluation of amlodipine against captopril in the monotherapeutic treatment of mild and moderate essential hypertension: interim results.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug Administr | 1991 |
Amlodipine compared to nitrendipine for the treatment of mild-to-moderate hypertension.
Topics: Amlodipine; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; N | 1991 |
Efficacy and tolerability of amlodipine in patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hypertension; | 1991 |
Clinical evaluation of amlodipine, a new long-acting calcium antagonist, in mild and moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Hear | 1991 |
Effects of antihypertensive drugs on glomerular function in normotensive and hypertensive subjects: hormonal aspects.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Dietary Carbohydrates; Dietary Proteins; Enalapril; F | 1991 |
Twenty-four-hour blood pressure control using once daily treatment with a calcium antagonist or an angiotensin converting enzyme inhibitor.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Enalapril; Female; Humans; Hypertension; Male; | 1991 |
Dose-response clarification in early drug development.
Topics: Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Doxazosin; Enalapril; Hum | 1991 |
[Acute reduction of blood pressure: comparative study of nifedipine and clonidine].
Topics: Adult; Aged; Blood Pressure; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1991 |
[Value of isometric and dynamic exercise tests with standard drug doses for selecting long-term antihypertensive treatment with vasodilators, adrenergic beta blockaders and diuretics].
Topics: Adult; Exercise; Exercise Test; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Nifedi | 1991 |
Double-blind, randomized comparative study of the antihypertensive effect of nicardipine slow-release and nifedipine slow-release in hypertensive patients with coronary heart disease.
Topics: Blood Pressure Monitors; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Human | 1991 |
Nifedipine alters serum theophylline levels in asthmatic patients with hypertension.
Topics: Adult; Asthma; Blood Pressure; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension; | 1991 |
Albuminuria induced by exercise in hypertensive type I and type II diabetic patients: a randomised, double-blind study on the effects of acute administration of captopril and nifedipine.
Topics: Adolescent; Adult; Albuminuria; Blood Pressure; Captopril; Diabetes Mellitus, Type 1; Diabetes Melli | 1991 |
Captopril, nifedipine and their combination for therapy of hypertensive urgencies.
Topics: Captopril; Drug Therapy, Combination; Humans; Hypertension; Nifedipine | 1991 |
Effects of nifedipine GITS and atenolol monotherapy on serum lipids, blood pressure, heart rate, and weight in mild to moderate hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Body Weight; Delayed-Action Preparations; Double-Blind Method | 1991 |
Plasma renin activity and norepinephrine as predictors for antihypertensive effects of nifedipine and captopril.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Female; | 1991 |
Long-term effect of nifedipine and hydrochlorothiazide on blood pressure and sodium homeostasis at varying levels of salt intake in mildly hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Homeostasis; Humans; Hydrochlorothiazide; | 1991 |
Natriuretic effect of calcium-channel blockers in hypertensives.
Topics: Adult; Calcium Channel Blockers; Diltiazem; Double-Blind Method; Hemodynamics; Humans; Hypertension; | 1991 |
Single-dose sublingual nifedipine as the only treatment in hypertensive urgencies and emergencies.
Topics: Administration, Sublingual; Adult; Aged; Capsules; Emergencies; Female; Hemodynamics; Humans; Hypert | 1991 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Monitors; Calcium Channel Blockers; Exercise; Female; Hem | 1990 |
A comparison of diltiazem, esmolol, nifedipine and nitroprusside therapy of post-CABG hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Coronary Artery Bypass; Coronary Circulation; Diltiazem | 1990 |
Effects of nifedipine versus hydralazine on sympathetic activity and cardiac function in patients with hypertension persisting on diuretic plus beta-blocker therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Catecholamines; Diuretics; Double-Blind Me | 1990 |
A comparative study of atenolol, nifedipine and their combination in the treatment of hypertension.
Topics: Adult; Atenolol; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyp | 1991 |
The effect of nifedipine on fetal umbilical artery Doppler waveforms in pregnancies complicated by hypertension.
Topics: Blood Flow Velocity; Blood Pressure; Double-Blind Method; Female; Heart Rate, Fetal; Humans; Hyperte | 1991 |
Comparison between perindopril and nifedipine in hypertensive and normotensive diabetic patients with microalbuminuria. Melbourne Diabetic Nephropathy Study Group.
Topics: Adolescent; Adult; Aged; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diab | 1991 |
Comparison of sublingual captopril and nifedipine in immediate treatment of hypertensive emergencies. A randomized, single-blind clinical trial.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Evaluation Studies as Topic; Fem | 1991 |
[Therapy comparison between the combination hydergine/nifedipine and nifedipine alone in patients with isolated systolic hypertension].
Topics: Aged; Blood Pressure; Dihydroergotoxine; Double-Blind Method; Drug Therapy, Combination; Female; Hea | 1991 |
Captopril compared to atenolol in mild to moderate hypertension in a randomized double-blind controlled trial.
Topics: Adult; Atenolol; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hyperten | 1991 |
[Clinical effects of nifedipine on blood pressure and left ventricular performance in patients with isolated hypertension].
Topics: Aged; Blood Pressure; Echocardiography, Doppler; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1991 |
Treatment of hypertensive urgencies with oral nifedipine, nicardipine, and captopril.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Female; Humans; Hypertension; Ma | 1991 |
Comparison of the effects of atenolol and nifedipine on glucose, insulin, and lipid metabolism in patients with hypertension.
Topics: Atenolol; Blood Glucose; Humans; Hypertension; Insulin; Kinetics; Lipids; Male; Middle Aged; Nifedip | 1991 |
The effects of antihypertensive agents on the quality of life in Indian hypertensives.
Topics: 1-Propanol; Adult; Aged; Atenolol; Captopril; Data Collection; Humans; Hypertension; India; Male; Mi | 1991 |
Cough and enalapril: assessment by spontaneous reporting and visual analogue scale under double-blind conditions.
Topics: Adult; Aged; Cough; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; | 1991 |
Short-term efficacy and safety of a single five-milligram dose of oral nifedipine in uncontrolled essential systemic hypertension.
Topics: Administration, Oral; Adult; Aged; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; | 1991 |
Assessment of quality of life by patient and spouse during antihypertensive therapy with atenolol and nifedipine gastrointestinal therapeutic system.
Topics: Adult; Aged; Atenolol; Central Nervous System; Delayed-Action Preparations; Double-Blind Method; Hum | 1991 |
Effects of short- and long-term administration of nifedipine on serum lipoprotein metabolism in patients with mild hypertension.
Topics: Administration, Oral; Apolipoproteins; Blood Pressure; Delayed-Action Preparations; Drug Administrat | 1990 |
Use of nifedipine in hypertension and Raynaud's phenomenon.
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Raynaud Disease | 1990 |
Long-term therapy with slow-release nifedipine in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Delayed-Action Preparations; Dose-Response Relationship, D | 1990 |
Effects of nifedipine on left ventricular diastolic function in hypertension; echo Doppler study.
Topics: Aged; Blood Pressure; Captopril; Diastole; Echocardiography, Doppler; Female; Heart Rate; Humans; Hy | 1990 |
Early regression of left ventricular diastolic abnormalities in hypertensive patients treated with nifedipine.
Topics: Adult; Blood Pressure; Diastole; Echocardiography; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1990 |
Nifedipine interactions in hypertensive patients.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Drug Interactions; Humans; Hypertension; Nifedipine | 1990 |
Effect of nifedipine administration on pulse wave velocity (PWV) of chronic hemodialysis patients--2-year trial.
Topics: Adult; Arteriosclerosis; Heart; Humans; Hypertension; Middle Aged; Nifedipine; Pulse; Renal Dialysis | 1990 |
Acute effects of sublingual nifedipine on left ventricular function in hemodialysis hypertensive patients.
Topics: Administration, Sublingual; Adult; Echocardiography, Doppler; Female; Humans; Hypertension; Male; Mi | 1990 |
Effect of nifedipine monotherapy on platelet aggregation in patients with untreated essential hypertension.
Topics: Adult; Blood Pressure; Humans; Hypertension; Lipids; Male; Middle Aged; Nifedipine; Platelet Aggrega | 1990 |
Co-dergocrine mesylate inhibits the increase in plasma catecholamines caused by nifedipine in essential hypertension.
Topics: Aldosterone; Catecholamines; Dihydroergotoxine; Drug Therapy, Combination; Female; Humans; Hypertens | 1990 |
Nifedipine gastrointestinal therapeutic system in the treatment of hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension (MATH) Study Group.
Topics: Adult; Aged; Blood Pressure; Body Weight; Delayed-Action Preparations; Female; Heart Rate; Hemodynam | 1990 |
Antihypertensive effectiveness of nifedipine gastrointestinal therapeutic system in the elderly. The Modern Approach to the Treatment of Hypertension (MATH) Study Group.
Topics: Aged; Aging; Blood Pressure; Cohort Studies; Delayed-Action Preparations; Electrolytes; Female; Hear | 1990 |
Endocrine and renal effects of nifedipine gastrointestinal therapeutic system in patients with essential hypertension. Results of a multicenter trial. The Modern Approach to the Treatment of Hypertension Study Group.
Topics: Aged; Blood Pressure; Diabetes Complications; Electrolytes; Endocrine Glands; Female; Heart Rate; He | 1990 |
[Antihypertensive therapy with co-dergocrine mesilate/nifedipine in comparison with nifedipine in type II diabetes].
Topics: Aged; Aged, 80 and over; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Dihydroergotoxine | 1990 |
[Effects of calcium antagonists or beta-blockade on left ventricular diastolic function in essential hypertension].
Topics: Adult; Atenolol; Diastole; Echocardiography; Echocardiography, Doppler; Female; Humans; Hypertension | 1990 |
[Comparative study of hypotensive effects of foridon and corinfar (results of the single-blind placebo-controlled study)].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Mid | 1990 |
[Comparison of chlorthalidone and sustained-action nifedipine in the treatment of mild to moderate arterial hypertension].
Topics: Aged; Chlorthalidone; Delayed-Action Preparations; Drug Evaluation; Female; Humans; Hypertension; Ma | 1990 |
[Regression of left ventricular hypertrophy in hypertensive patients under long-term therapy with antihypertensive agents].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Female; Gallopamil; Humans; Hype | 1990 |
Effects of amlodipine on blood pressure, heart rate, catecholamines, lipids and responses to adrenergic stimulus.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Catecholamines; Doubl | 1990 |
Arterial vasodilator effects of the dihydropyridine calcium antagonist amlodipine alone and in combination with verapamil in systemic hypertension.
Topics: Amlodipine; Calcium Channel Blockers; Drug Therapy, Combination; Female; Forearm; Humans; Hypertensi | 1990 |
Amlodipine with enalapril therapy in moderate-severe essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy | 1990 |
Assessment of left ventricular function after sublingual administration of nifedipine in patients with moderate to severe hypertension.
Topics: Administration, Sublingual; Adult; Blood Pressure; Cardiomegaly; Echocardiography; Echocardiography, | 1990 |
The calcium antagonist isradipine in the therapy of hypertension. A double-blind crossover comparison with nifedipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; | 1990 |
[Electrocardiographic and echocardiographic changes during antihypertensive therapy].
Topics: Acebutolol; Adolescent; Adult; Aged; Antihypertensive Agents; Captopril; Cardiomegaly; Chlorthalidon | 1990 |
[Effect of moderate salt restriction on the antihypertensive action of nifedipine: a double blind study].
Topics: Clinical Trials as Topic; Diet, Sodium-Restricted; Double-Blind Method; Drug Evaluation; Humans; Hyp | 1990 |
Long-term treatment of hypertension in the elderly with a combination of atenolol and nifedipine.
Topics: Aged; Atenolol; Clinical Trials as Topic; Delayed-Action Preparations; Dizziness; Drug Combinations; | 1990 |
Comparative efficacy and safety of enalapril and sustained-release nifedipine in patients with mild to moderate hypertension. The Enalapril vs Nifedipine French Study Group.
Topics: Double-Blind Method; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Multicenter Studies | 1990 |
Evaluation of the clinical pharmacology of nilvadipine in patients with mild to moderate essential hypertension.
Topics: Blood Pressure; Double-Blind Method; Drug Evaluation; Heart Rate; Humans; Hypertension; Multicenter | 1990 |
Spironolactone versus nifedipine in essential hypertension.
Topics: Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Female; | 1990 |
Intranasal nifedipine for post-bypass hypertension--hemodynamics and pharmacokinetics.
Topics: Administration, Intranasal; Blood Pressure; Coronary Artery Bypass; Dose-Response Relationship, Drug | 1990 |
[Hypertension in the elderly. Comparison of the efficacy and tolerability of labetalol and nifedipine. A multicenter, randomized, single-blind study].
Topics: Aged; Aged, 80 and over; Humans; Hypertension; Labetalol; Multicenter Studies as Topic; Nifedipine; | 1990 |
Hypertension in the elderly: a study of a combination of atenolol and nifedipine.
Topics: Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Drug Combinations; Female; Heart Rate; Hum | 1990 |
A dose finding study of the combination of atenolol and nifedipine in hypertension.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Me | 1990 |
Enalapril and nifedipine in the treatment of mild to moderate essential hypertension: a 6 month comparison.
Topics: Adolescent; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Enalapril; | 1990 |
Comparison of the efficacy and long-term tolerability of a combination of atenolol and nifedipine with atenolol alone in the treatment of hypertension.
Topics: Adult; Aged; Atenolol; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; M | 1990 |
A comparison of verapamil and nifedipine on quality of life.
Topics: Adult; Aged; Blood Pressure; Cognition; Double-Blind Method; Female; Humans; Hypertension; Male; Mid | 1990 |
Effects of nifedipine on systemic hydraulic vascular load in patients with hypertension.
Topics: Aorta; Blood Flow Velocity; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hypertension; | 1990 |
[Effect of the treatment on hemodynamic indicators and plasma testosterone level in patients with juvenile hypertension].
Topics: Adolescent; Adult; Antihypertensive Agents; Hemodynamics; Humans; Hypertension; Nifedipine; Proprano | 1990 |
[The effect of korinfar on the systemic hemodynamics and myocardial contractile function in hypertension patients].
Topics: Adult; Chronic Disease; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardial Co | 1990 |
Effects of different calcium antagonists on proteinuria associated with diabetes mellitus.
Topics: Aged; Creatinine; Delayed-Action Preparations; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Di | 1990 |
Antihypertensive effects of a new sustained-release formulation of nifedipine.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Delayed-Action Preparations; Double-Blind Metho | 1990 |
Influence of co-dergocrine mesilate/nifedipine compared to mefruside/nifedipine on circadian blood pressure in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Dihydroergotoxine; Drug Ther | 1990 |
Verapamil versus nifedipine in slow-release preparations for the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Drug Tolerance; Female; Humans; Hypertensi | 1990 |
[Blood pressure monitoring in aged hypertensive patients treated with sustained-release nicardipine or nifedipine].
Topics: Aged; Aged, 80 and over; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Ni | 1990 |
Labetalol and nifedipine in the management of essential hypertension.
Topics: Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Labetalol; Male; Middle Aged; Nif | 1990 |
Effect of calcium and calcium blockers in hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Gluconate; Female; Humans; Hypertension; | 1990 |
[The results of a clinical study of the preparation kardil].
Topics: Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipine; USS | 1990 |
Comparative trial of nifedipine retard and atenolol in the treatment of elderly patients with mild to moderate hypertension.
Topics: Aged; Atenolol; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Female; Human | 1990 |
Control of blood pressure in hypertensive patients with felodipine extended release or nifedipine retard.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Drug Evaluation; Felo | 1990 |
Verapamil but not nifedipine impairs left ventricular function during exercise in hypertensive patients.
Topics: Blood Pressure; Exercise; Female; Gated Blood-Pool Imaging; Heart Rate; Humans; Hypertension; Male; | 1990 |
Interaction of enalapril with sodium restriction, diuretics, and slow-channel calcium-blocking drugs.
Topics: Blood Pressure; Combined Modality Therapy; Diet, Sodium-Restricted; Drug Interactions; Drug Synergis | 1990 |
[The effects of nifedipine and captopril on blood pressure, clinical chemical parameters and general health].
Topics: Adult; Aged; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1990 |
Long-acting nifedipine versus metoprolol as monotherapy for essential hypertension. A randomized, controlled crossover study.
Topics: Adult; Aged; Delayed-Action Preparations; Humans; Hypertension; Metoprolol; Middle Aged; Nifedipine; | 1990 |
Regression of left ventricular hypertrophy in hypertension: comparative effects of three different drugs.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Catecholamines; Female; Humans; Hypert | 1985 |
Nifedipine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy, in ischaemic heart disease, hypertension and related cardiovascular disorders.
Topics: Absorption; Adrenergic beta-Antagonists; Angina Pectoris; Animals; Blood Platelets; Calcium Channel | 1985 |
Effects of intravenous ketanserin on severely hypertensive patients with double-blind crossover assessment of central side-effects.
Topics: Adult; Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; In | 1987 |
Central hemodynamic changes of calcium antagonists at rest and during exercise in essential hypertension.
Topics: Adult; Calcium Channel Blockers; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nife | 1987 |
Comparative trial of lisinopril and nifedipine in mild to severe essential hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Clinical Trials as Topic; Double-Blind Met | 1987 |
Ketanserin versus nifedipine in the treatment of essential hypertension in patients over 50 years old: an international multicenter study.
Topics: Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Flushing; Heart Rate; Humans; Hyperte | 1987 |
Studies on the natriuretic effect of nifedipine in hypertensive patients: increase in levels of plasma atrial natriuretic factor without participation of the renal kallikrein-kinin system.
Topics: Adult; Aprotinin; Atrial Natriuretic Factor; Blood Pressure; Creatinine; Drug Evaluation; Humans; Hy | 1987 |
Effect of calcium antagonists on ambulatory blood pressure and its variations.
Topics: Adult; Aged; Ambulatory Care; Atenolol; Blood Pressure; Double-Blind Method; Drug Therapy, Combinati | 1987 |
Effects of reactive hyperemia and nifedipine on forearm vascular resistance in essential hypertension: evidence for functional abnormality.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Forearm; Humans; Hyperemia; Hypertension; Ischemia; Male | 1987 |
Calcium antagonists and thiazide diuretics in the treatment of hypertension.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Delayed-Action Preparations; Drug Therapy, Combination; | 1987 |
Acute hemodynamic effect of nifedipine in hypertensives with chronic renal failure: the influence of volume status.
Topics: Adult; Blood Pressure; Glomerulonephritis; Heart Rate; Hematocrit; Hemodynamics; Humans; Hypertensio | 1987 |
Regression of cardiac hypertrophy after antihypertensive therapy with nifedipine and captopril.
Topics: Adult; Blood Pressure; Captopril; Cardiomegaly; Echocardiography; Heart; Heart Rate; Humans; Hyperte | 1987 |
Effect of nifedipine and verapamil on carbohydrate metabolism in hypertensive patients with impaired glucose tolerance.
Topics: Adult; Arginine; Blood Glucose; Carbohydrate Metabolism; Glucose Tolerance Test; Growth Hormone; Hum | 1987 |
A double-blind, placebo-controlled, crossover trial to investigate the additive hypotensive effect of a diuretic (mefruside) to that produced by nifedipine.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Diuretics; Double-Blind Method; Drug Synergis | 1987 |
Calcium antagonists and sodium balance: effect of changes in sodium intake and of the addition of a thiazide diuretic on the blood pressure lowering effect of nifedipine.
Topics: Adult; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; | 1987 |
Comparative pharmacokinetics and antihypertensive effects of the nifedipine tablet and capsule.
Topics: Aged; Blood Pressure; Capsules; Double-Blind Method; Half-Life; Humans; Hypertension; Male; Metoprol | 1987 |
Acute antihypertensive effect of angiotensin converting enzyme inhibition and calcium entry blockade.
Topics: Adult; Angiotensin II; Blood Pressure; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Mi | 1987 |
Comparative efficacy of lisinopril and nifedipine retard in essential hypertension: a double-blind, placebo-controlled trial.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Double-Blind Method; Enalapri | 1987 |
Slow-release metoprolol and nifedipine in essential hypertension: 24 hour noninvasive ambulatory blood pressure monitoring.
Topics: Adult; Ambulatory Care; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Female; Hu | 1987 |
Effects of clonidine and nifedipine on left ventricular hypertrophy and muscle mass in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Clonidine; Echocardiography; Female; Heart; Heart Rate; H | 1987 |
Multicenter placebo-controlled comparison of amlodipine and atenolol in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Atenolol; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topi | 1988 |
A randomized placebo-controlled comparison of amlodipine and atenolol in mild to moderate systemic hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Atenolol; Blood Pressure; Calcium Channel Blockers; Clinical Tr | 1988 |
Once-daily amlodipine in the treatment of mild to moderate hypertension.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Heart Rate | 1988 |
A double-blind evaluation of the effect of amlodipine on ambulatory blood pressure in hypertensive patients.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; | 1988 |
Amlodipine: a double-blind evaluation of the dose-response relationship in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Re | 1988 |
A double-blind crossover comparison of amlodipine and placebo added to captopril in moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; | 1988 |
Comparison of amlodipine and verapamil in the treatment of mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as To | 1988 |
Long-term open evaluation of amlodipine versus hydrochlorothiazide in patients with essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hydro | 1988 |
Double-blind comparison of amlodipine and hydrochlorothiazide in patients with mild to moderate hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as To | 1988 |
Acute and chronic effects of dihydropyridines on triglycerides in humans.
Topics: Adult; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Double-Blind Method; Fe | 1988 |
Treatment of hypertensive urgencies and emergencies with nitrendipine, nifedipine, and clonidine: effect on blood pressure and heart rate.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy, Combination; Emerg | 1988 |
Factors determining the response to calcium antagonists in hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Hum | 1988 |
Nifedipine-prazosin interaction in patients with essential hypertension.
Topics: Adult; Blood Pressure; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Female; He | 1989 |
Nifedipine as low-dose monotherapy for essential hypertension: a primary care study.
Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Humans; Hypertension; Middle Aged; Nife | 1989 |
Calcium channel blockers. Potential medical benefits and side effects.
Topics: Blood Pressure; Calcium Channel Blockers; Diltiazem; Exercise; Humans; Hypertension; Nifedipine; Uni | 1989 |
Safety and efficacy of amlodipine added to hydrochlorothiazide therapy in essential hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy | 1989 |
A dose-response study of amlodipine in mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dose-Re | 1989 |
Antihypertensive effectiveness of amlodipine in combination with hydrochlorothiazide.
Topics: Alanine Transaminase; Amlodipine; Aspartate Aminotransferases; Calcium Channel Blockers; Cholesterol | 1989 |
A comparison of amlodipine, verapamil and placebo in the treatment of mild to moderate hypertension. Amlodipine Study Group.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Huma | 1989 |
Increase of plasma atrial natriuretic peptide levels after sublingual administration of nifedipine in essentially hypertensive patients.
Topics: Adult; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Heart Rate; Humans; Hypertension; Mid | 1989 |
Lisinopril versus slow-release nifedipine in the treatment of mild to moderate hypertension: a multicentre study. The Cooperative Study Group.
Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Delayed-Action Pr | 1989 |
[Regression of left heart hypertrophy in hypertensive patients as a result of antihypertensive therapy].
Topics: Acebutolol; Adult; Antihypertensive Agents; Atenolol; Cardiac Output; Cardiac Volume; Cardiomegaly; | 1989 |
Prediction of response to antihypertensive therapy with enalapril and nifedipine.
Topics: Blood Pressure; Drug Evaluation; Enalapril; Humans; Hypertension; Models, Biological; Nifedipine; Pr | 1989 |
[Beta receptor block versus calcium antagonism. A comparative study of bopindolol and nifedipine with special regard to quality of life].
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dou | 1989 |
The safety of amlodipine.
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; D | 1989 |
The efficacy and tolerability of nifedipine (NIF) and nisoldipine (NIS) both alone and combined with a beta-blocker in patients with essential hypertension: a multicenter, parallel-group study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Body Weight; Double-Blind Method; Drug The | 1989 |
[Cicletanine administered with other antihypertensive agents].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Clonidi | 1989 |
Captopril: contrasting effects of adding hydrochlorothiazide, propranolol, or nifedipine.
Topics: Blood Pressure; Body Weight; Captopril; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hype | 1985 |
Antihypertensive treatment using calcium antagonists in combination with captopril rather than diuretics.
Topics: Adult; Aged; Amiloride; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril | 1985 |
Short-term and long-term renal response to nifedipine monotherapy.
Topics: Clinical Trials as Topic; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Kidney Function | 1989 |
[Antihypertensive effect and tolerance to urapidil. Comparison with nifedipine in a multicenter double-blind study].
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Clinical Trials as Topic; Double-Blind Meth | 1989 |
A double-blind randomized cross-over study of the efficacy and tolerability of nifedipine and nitrendipine in the treatment of mild to moderate hypertension.
Topics: Adult; Aged; Blood Chemical Analysis; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1989 |
Antihypertensive therapy in the geriatric patient. I: A review of the role of calcium channel blockers.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Humans; Hyperte | 1989 |
The effects of verapamil, diltiazem, nifedipine and propranolol on metabolic control in hypertensives with non-insulin dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Blood Pressure; Cholesterol; Diabetes Mellitus, Type 2; Diltiazem; Female; Fruc | 1989 |
A comparison of felodipine and nifedipine as monotherapies for the treatment of mild to moderate hypertension.
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Double-Blind Method; Felodipine; Femal | 1989 |
Calcium channel blockade in heart failure.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Heart; Heart Failure; Hemodyna | 1989 |
Comparison of nisoldipine and atenolol in the treatment of essential hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Calcium Channel Blockers; Captopril; Heart Rate; Humans; Hype | 1989 |
[Age and efficacy of new long acting calcium blocker, nisoldipine, is essential hypertension].
Topics: Adult; Age Factors; Aged; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topi | 1989 |
[The effect of nifedipine and fentanyl on changes in the circulatory reaction to endotracheal intubation].
Topics: Adult; Blood Pressure; Epinephrine; Female; Fentanyl; Heart Rate; Humans; Hypertension; Intubation, | 1989 |
Antihypertensive and humoral effects of nifedipine in essential hypertension uncontrolled by hydrochlorothiazide alone.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therap | 1989 |
Dependent oedema and attenuation of postural vasoconstriction associated with nifedipine therapy for hypertension in diabetic patients.
Topics: Adult; Aged; Clinical Trials as Topic; Diabetes Complications; Edema; Female; Humans; Hypertension; | 1989 |
[Comparative study of the use of nifedipine and captopril in hypertensive emergencies].
Topics: Adolescent; Adult; Aged; Blood Pressure; Captopril; Clinical Trials as Topic; Drug Evaluation; Emerg | 1989 |
Chlorthalidone does not increase the hypotensive effect of nifedipine in essential hypertensives: a crossover multicentre study.
Topics: Adult; Aged; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Synergism; Drug Therapy, Comb | 1989 |
Haemodynamic parameters in hypertensive patients: changes induced by lacidipine and nifedipine.
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Hem | 1989 |
Short-term effect of captopril and nifedipine on micro-albuminuria induced by exercise in hypertensive diabetic patients.
Topics: Albuminuria; Captopril; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Drug Evaluation; Exerc | 1989 |
[Treatment with nifedipine retard: increasing doses as a therapeutic method].
Topics: Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Evalua | 1989 |
Attenuation of electroconvulsive therapy induced hypertension with sublingual nifedipine.
Topics: Administration, Sublingual; Aged; Blood Pressure; Depressive Disorder; Drug Evaluation; Electroconvu | 1989 |
Nifedipine in acute hypertensive emergencies in pregnancy.
Topics: Acute Disease; Adolescent; Adult; Blood Pressure; Dihydralazine; Emergencies; Female; Humans; Hypert | 1989 |
Nifedipine, but not propranolol, improves left ventricular systolic and diastolic function in patients with hypertension.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; M | 1989 |
The nifedipine gastrointestinal therapeutic system in the treatment of hypertension.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Double-Blind Method; Female; Humans; Hyperte | 1989 |
Individual responses to converting enzyme inhibitors and calcium antagonists.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Clinical | 1988 |
Lisinopril in essential hypertension: a six month comparative study with nifedipine.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blin | 1987 |
A comparison of long acting nifedipine and enalapril in elderly hypertensives: a randomised, single-blind, cross-over study.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Enal | 1988 |
The effect of nifedipine and captopril on platelet activation and prostanoid production in essential hypertension.
Topics: Adult; Blood Platelets; Blood Pressure; Captopril; Cyclic AMP; Epoprostenol; Female; Heart Rate; Hum | 1988 |
Humoral and haemodynamic interactions between clonidine and nifedipine in human essential hypertension.
Topics: Clonidine; Drug Interactions; Hemodynamics; Humans; Hypertension; Nifedipine | 1985 |
Antihypertensive effects of felodipine compared with placebo.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Diuretics; Drug T | 1985 |
Antihypertensive effect of felodipine combined with beta-blockade. A comparison between 2 and 3 daily dosages.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Body Weight; Clin | 1985 |
Felodipine in comparison with prazosin in hypertensive patients inadequately controlled on beta-blockade.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Femal | 1985 |
Working ability and exercise tolerance during treatment of a mild hypertension. I. Comparison between a beta-adreno-receptor blocking drug and a calcium antagonist.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Clinical Tri | 1985 |
Antihypertensive therapy with calcium-channel blockers: comparison with beta blockers.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Clinical Tri | 1985 |
Comparison of sublingual captopril and nifedipine.
Topics: Administration, Oral; Capsules; Captopril; Clinical Trials as Topic; Humans; Hypertension; Male; Mid | 1986 |
Nifedipine tablet vs. hydralazine in patients with persisting hypertension who receive combined diuretic and beta-blocker therapy.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aged; Analysis of Variance; Blood Pressure | 1986 |
Relative potency of a beta-blocking and a calcium entry blocking agent as antihypertensive drugs in black patients.
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Black or | 1986 |
Felodipine vs hydralazine: a controlled trial as third line therapy in hypertension. Cooperative Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Double-Blind Method; Felodipine; Female; Humans; Hydralazine; | 1986 |
Calcium antagonists and the second drug for hypertensive therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; | 1986 |
Comparison of ketanserin and slow-release nifedipine added to the treatment of hypertensive patients uncontrolled by a thiazide diuretic plus beta-adrenoceptor blocker.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Benzothiadiazines; Blood Pressure; Body Weight; Clinical T | 1987 |
Nifedipine and atenolol singly and combined for treatment of essential hypertension: comparative multicentre study in general practice in the United Kingdom. Nifedipine-Atenolol Study Review Committee.
Topics: Adolescent; Adult; Aged; Atenolol; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, C | 1988 |
Sympathetic (alpha-beta) or calcium channel blockade for hypertensive myocardial infarction? A haemodynamic comparison of labetalol and nifedipine.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; He | 1988 |
[Betaxolol versus nifedipine in the treatment of essential hypertension].
Topics: Adrenergic beta-Antagonists; Betaxolol; Blood Pressure; Echocardiography; Female; Heart Rate; Humans | 1988 |
Oral nifedipine vs oral clonidine in the treatment of urgent hypertension.
Topics: Administration, Oral; Adult; Aged; Clonidine; Double-Blind Method; Emergencies; Female; Humans; Hype | 1989 |
Antihypertensive and cardiovascular effects of nitrendipine: a controlled study vs. placebo.
Topics: Administration, Oral; Adult; Blood Pressure; Double-Blind Method; Drug Evaluation; Echocardiography; | 1985 |
Age, race, blood pressure and renin: predictors for antihypertensive treatment with calcium antagonists.
Topics: Adolescent; Adult; Age Factors; Aged; Black People; Blood Pressure; Calcium Channel Blockers; Female | 1985 |
Hemodynamic and metabolic effects of the calcium channel blocking agent nitrendipine.
Topics: Administration, Oral; Adult; Aged; Blood Glucose; Blood Pressure; Cholesterol; Chromatography, High | 1986 |
Pharmacokinetics of calcium channel blocking agents.
Topics: Administration, Oral; Angina Pectoris; Atrial Fibrillation; Biological Availability; Cardiomegaly; C | 1986 |
Nitrendipine vs. long-acting nifedipine in mild, moderate and severe hypertension.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nife | 1986 |
Once daily amlodipine in the treatment of mild to moderate hypertension.
Topics: Adult; Amlodipine; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind | 1987 |
Comparison of bisoprolol with nifedipine for treatment of essential hypertension in the elderly: comparative double-blind trial.
Topics: Aged; Aging; Bisoprolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Heart Rate; | 1987 |
[Calcium antagonists and blood filterability].
Topics: Adult; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Erythrocyte De | 1987 |
[Effects of chronic administration of several calcium antagonists on pituitary release of TSH].
Topics: Adult; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hyper | 1987 |
[Comparison of the effects of oxprenolol and nifedipine on blood pressure at rest and during physical exercise in essential hypertension].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Exercise; Female | 1988 |
Myocardial metabolism, catecholamine balance, and left ventricular function during coronary artery surgery: effects of nitroprusside and nifedipine.
Topics: Blood Pressure; Cardiac Output; Coronary Artery Bypass; Epinephrine; Heart Rate; Humans; Hypertensio | 1987 |
Influence of calcium entry blockade on alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in the forearm of hypertensive patients.
Topics: Adult; Azepines; Calcium Channel Blockers; Female; Forearm; Hemodynamics; Humans; Hypertension; Isra | 1987 |
[Pharmacodynamics of cordipine in hypertension].
Topics: Administration, Sublingual; Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as | 1988 |
Monotherapy of hypertension with darodipine: a new calcium-channel blocker.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertensio | 1988 |
The efficacy and tolerability of atenolol, nifedipine, and their combination in the management of hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Combinati | 1988 |
Pathogenesis of hypertension in hemodialysis patients: a pharmacological study.
Topics: Adult; Aged; Blood Pressure; Captopril; Clonidine; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1988 |
Comparative effects of captopril and nifedipine on diastolic and systolic cardiac function in elderly hypertensive patients.
Topics: Aged; Captopril; Clinical Trials as Topic; Diastole; Female; Heart Rate; Humans; Hypertension; Male; | 1988 |
Hypertensive emergencies in old age: effects of angiotensin converting enzyme inhibition.
Topics: Administration, Sublingual; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Blood | 1988 |
Rapid development of tolerance to the antihypertensive effect of nisoldipine.
Topics: Adolescent; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Double- | 1988 |
[Use of foridon in the treatment of arterial hypertension and hypertension of the lesser circulation].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Clonidine; Drug Syne | 1988 |
[Treatment of idiopathic arterial hypertension with delayed-action nifedipine].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Delayed-Action Prepa | 1988 |
[Nifedipine therapy in uncomplicated essential hypertension and hypertensive problem cases].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hyperten | 1988 |
Nicardipine versus nifedipine: multicentre controlled trial in essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relations | 1988 |
Comparative effects of pinacidil and nifedipine in the treatment of arterial hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Guanidines; | 1988 |
Comparison of nitroglycerine, verapamil and nifedipine in the management of arterial pressure during coronary artery surgery.
Topics: Blood Pressure; Coronary Vessels; Electrocardiography; Hemodynamics; Humans; Hypertension; Intraoper | 1986 |
Effects of first-line antihypertensive agents on sexual function and sex hormones.
Topics: Adult; Antihypertensive Agents; Atenolol; Captopril; Estradiol; Follicle Stimulating Hormone; Humans | 1988 |
Addition of chlorthalidone to slow-release nifedipine in the treatment of arterial hypertension: a controlled study versus placebo.
Topics: Adult; Chlorthalidone; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hyper | 1988 |
A randomized double-blind crossover study of nicardipine and nifedipine in patients with angina pectoris and concomitant essential hypertension.
Topics: Adult; Angina Pectoris; Blood Pressure; Double-Blind Method; Heart; Humans; Hypertension; Male; Midd | 1988 |
[Antihypertensive and anti-ischemic effect of nitrendipine. Double-blind, randomized, crossover and placebo controlled acute study].
Topics: Angina Pectoris; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Double-Blind | 1985 |
[Antihypertensive effect of nitrendipine, nifedipine and acebutolol and their combination on resting and exercise blood pressure in hypertensive patients].
Topics: Acebutolol; Adult; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Exercise Test | 1985 |
Muzolimine and nitrendipine in the treatment of arterial hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Captopril; Clinical Trials as Topic; Double-Blind M | 1985 |
[Verapamil and nitrendipine in beta blocker-resistant hypertensive patients].
Topics: Atenolol; Calcium Channel Blockers; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged | 1985 |
Nitrendipine and atenolol: comparison and combination in the treatment of arterial hypertension.
Topics: Adult; Atenolol; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinical Trials as Topic; Do | 1985 |
Benidipine hydrochloride--a new calcium-channel blocker of the dihydropyridine type. Pharmacokinetics, pharmacodynamics, tolerance and dose finding in mild to moderate hypertension.
Topics: Adult; Antihypertensive Agents; Biological Availability; Blood Pressure; Calcium Channel Blockers; D | 1988 |
The effect of sublingual nifedipine on uteroplacental blood flow in hypertensive pregnancy.
Topics: Adult; Blood Flow Velocity; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Placenta; Preg | 1988 |
Interaction of slow-channel calcium blocking drugs with sodium restriction, diuretics and angiotensin converting enzyme inhibitors.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Diet, Sodium-Restricted; Diuretics; Drug I | 1988 |
Effects of long term treatment with pinacidil and nifedipine on left ventricular anatomy and function in patients with mild to moderate systemic hypertension.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Echocardiography; Female; Guanidines; Heart Ventricle | 1988 |
Calcium antagonists: use in hypertension evaluation of calcium antagonists in combination with diuretics.
Topics: Bendroflumethiazide; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; | 1988 |
[Antihypertensive therapy in young hypertensive patients. Effect of tredalat in comparison with adalat on blood pressure behavior and metabolism, especially renin excretion].
Topics: Acebutolol; Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Dr | 1988 |
[Comparative evaluation of the hypotensive effects of finoptin and corinfar after their sublingual administration].
Topics: Administration, Sublingual; Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Calciu | 1988 |
Atenolol and sustained release nifedipine alone and in combination in hypertension. A randomised, double-blind, crossover study.
Topics: Adult; Aged; Atenolol; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Delayed-Action Prepa | 1988 |
Efficacy and tolerability of atenolol, nifedipine and their combination in the management of hypertension.
Topics: Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Creatinine; Double-Blind Method; Dr | 1988 |
Atenolol-nifedipine combinations compared to atenolol alone in hypertension: efficacy and tolerability.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Dr | 1988 |
Postoperative hypertension: a comparison of diltiazem, nifedipine, and nitroprusside.
Topics: Clinical Trials as Topic; Coronary Artery Bypass; Diltiazem; Female; Ferricyanides; Hemodynamics; Hu | 1988 |
Captopril and nifedipine in combination for moderate to severe essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Captopril; Drug Administration Schedule; Drug | 1987 |
Ketanserin compared to nifedipine and methyldopa in patients aged above 50 years: two international multicentre studies. For the International Study Group.
Topics: Blood Pressure; Body Weight; Clinical Trials as Topic; Drug Therapy, Combination; Female; Heart Rate | 1986 |
Changes in systemic and pulmonary vascular reactivity in hypertension following nifedipine and verapamil.
Topics: Adult; Blood Circulation; Blood Pressure; Clinical Trials as Topic; Cognition; Cold Temperature; Hem | 1987 |
[Acute treatment of arterial hypertension using calcium antagonists: comparison between diltiazem and nifedipine].
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Emergencies; Female; Heart Rate; H | 1987 |
The effects of bendroflumethiazide added to nifedipine in patients with hypertension.
Topics: Adult; Bendroflumethiazide; Blood Glucose; Blood Pressure; Body Weight; Clinical Trials as Topic; De | 1987 |
Cross-over comparison between captopril and nifedipine.
Topics: Captopril; Drug Therapy, Combination; Humans; Hypertension; Nifedipine | 1986 |
Evaluation of the antihypertensive effect of nifedipine.
Topics: Adolescent; Adult; Aged; Blood Pressure; Child; Clinical Trials as Topic; Female; Humans; Hypertensi | 1987 |
[Sublingual hypotensive treatment. Does it compare homogeneous groups of hypertensive patients?].
Topics: Administration, Oral; Aged; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1987 |
Captopril and nifedipine interactions in the treatment of essential hypertensives: a crossover study.
Topics: Adult; Aged; Captopril; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Fema | 1987 |
Is nifedipine a suitable first-line treatment for essential hypertension in general practice?
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; | 1987 |
Double-blind, placebo-controlled trial of twice-daily nifedipine as a step-2 agent in mild essential hypertension.
Topics: Adult; Aged; Benzothiadiazines; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparation | 1987 |
Nifedipine GITS and hydrochlorothiazide in essential hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparation | 1987 |
Innovative drug delivery systems in cardiovascular medicine: nifedipine-GITS and clonidine-TTS.
Topics: Administration, Cutaneous; Angina Pectoris; Clinical Trials as Topic; Clonidine; Delayed-Action Prep | 1987 |
[Cordipin in the treatment of primary arterial hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertensi | 1987 |
[Delayed-action nifedipine in the treatment of primary hypertension: its effect on blood pressure and serum lipids and lipoproteins].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Delayed-Action Prepa | 1987 |
[Nifedipine (Cordipin) in the monotherapy of mild and moderate arterial hypertension].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertensi | 1987 |
Multicenter comparison of the nifedipine gastrointestinal therapeutic system and long-acting propranolol in patients with mild to moderate systemic hypertension receiving diuretics. A preliminary experience.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Diuretics; Female; Heart Rate; Humans; Hypertens | 1987 |
Antihypertensive effectiveness of the nifedipine gastrointestinal therapeutic system.
Topics: Adult; Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Drug Evalua | 1987 |
Nifedipine and acebutolol in combination for the treatment of moderate to severe essential hypertension.
Topics: Acebutolol; Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hype | 1987 |
Nisoldipine. Central haemodynamics at rest and during exercise in essential hypertension: acute and chronic studies.
Topics: Adult; Calcium Channel Blockers; Cardiac Output; Female; Hemodynamics; Humans; Hypertension; Male; N | 1988 |
Effect of nifedipine on cardiovascular responses to laryngoscopy and intubation.
Topics: Administration, Sublingual; Adult; Anesthesia, General; Hemodynamics; Humans; Hypertension; Intubati | 1988 |
Aims of combination therapy--improved quality of life or better blood pressure control?
Topics: Atenolol; Blood Pressure; Delayed-Action Preparations; Drug Therapy, Combination; Humans; Hypertensi | 1988 |
A double-blind study of the blood pressure lowering effect of a thiazide diuretic in hypertensive patients already on nifedipine and a beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Double-Blind Method; Drug Therapy, Combi | 1987 |
Comparison of the efficacy of nicardipine, a new calcium channel blocker, with nifedipine in the treatment of mild to moderate essential hypertension.
Topics: Adult; Aged; Blood Pressure; Body Weight; Female; Heart Rate; Humans; Hypertension; Male; Middle Age | 1987 |
Effect of nifedipine on carbohydrate metabolism and serum lipoproteins in hypertensive patients with and without diabetes mellitus.
Topics: Adult; Aged; Blood Pressure; Carbohydrate Metabolism; Diabetes Complications; Diabetes Mellitus; Fem | 1987 |
Effects of a low-sodium diet on antihypertensive and natriuretic responses to acute administration of nifedipine.
Topics: Adult; Aged; Blood Pressure; Combined Modality Therapy; Diet, Sodium-Restricted; Double-Blind Method | 1987 |
Nifedipine for postoperative blood pressure control following coronary artery vein grafts.
Topics: Blood Pressure; Coronary Artery Bypass; Heart Rate; Humans; Hypertension; Nifedipine; Nitroprusside; | 1986 |
The role of calcium channel blockers in the treatment of hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diltiaz | 1986 |
Calcium-channel blockers for combined angina pectoris and systemic hypertension.
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chr | 1986 |
Instant and sustained-release verapamil in the treatment of essential hypertension.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; E | 1986 |
[Nifedipine with a long-term effect in older hypertensive patients. A controlled clinical trial].
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Fe | 1986 |
Atenolol plus nifedipine for mild to moderate systemic hypertension after fixed doses of either agent alone.
Topics: Adult; Atenolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combin | 1986 |
Treatment of essential hypertension with felodipine in combination with a diuretic.
Topics: Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Double-Blind Method; | 1986 |
[Age and efficacy of calcium entry blocker in essential hypertension--double blind trial using nicardipine].
Topics: Adult; Age Factors; Aged; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Method; F | 1986 |
[A comparison between nicardipine hydrochloride (YC-93) and trimethaphan camsylate for treatment of acute hypertension during surgery. A double blind study in 12 institutions].
Topics: Acute Disease; Adolescent; Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Double-Bl | 1986 |
[Antihypertensive effects of nicardipine hydrochloride (YC-93) on patients with hypertension during neuroleptanesthesia].
Topics: Adult; Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intrao | 1986 |
[Result of randomized comparative clinical study of nicardipine hydrochloride and trimethaphan camsylate on control of blood pressure during surgery].
Topics: Aged; Antihypertensive Agents; Clinical Trials as Topic; Female; Humans; Hypertension; Intraoperativ | 1986 |
Blood pressure and hormonal responses to sublingual nifedipine in acute childhood hypertension.
Topics: Adolescent; Blood Pressure; Catecholamines; Child; Child, Preschool; Clinical Trials as Topic; Drug | 1986 |
A randomized comparison of nifedipine and sodium nitroprusside in severe hypertension.
Topics: Administration, Oral; Clinical Trials as Topic; Costs and Cost Analysis; Critical Care; Ferricyanide | 1986 |
Dose response and length of action of nifedipine capsules and tablets in patients with essential hypertension: a randomised crossover study.
Topics: Adult; Capsules; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hyperte | 1986 |
Calcium-channel blockers for hypertensive emergencies.
Topics: Adult; Calcium Channel Blockers; Child; Clinical Trials as Topic; Emergencies; Heart Rate; Humans; H | 1986 |
Monotherapy of mild hypertension with nifedipine.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hyperten | 1986 |
Calcium channel blockers in the management of hypertension in the elderly.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Female; Heart Rate; Humans | 1986 |
Comparison of sublingual captopril and nifedipine in hypertensive crises.
Topics: Captopril; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Nifedipine; Random A | 1987 |
[Effectiveness and tolerance of slow-release nifedipine in the treatment of moderate arterial hypertension in the elderly. A comparative multicenter study].
Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Met | 1986 |
[Nisoldipine in the treatment of essential hypertension. Efficacy and tolerance].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1987 |
[Rapid control of acute hypertensive conditions by administration of sublingual nifedipine].
Topics: Acute Disease; Blood Pressure; Clinical Trials as Topic; Female; Humans; Hypertension; Male; Middle | 1986 |
Calcium antagonists in the treatment of arterial hypertension in the elderly.
Topics: Age Factors; Aged; Aged, 80 and over; Calcium Channel Blockers; Clinical Trials as Topic; Female; Hu | 1986 |
[Physical performance in antihypertensive therapy. Results of a calcium antagonist-beta blocker combination].
Topics: Acebutolol; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Exercise Test; | 1987 |
Comparison of nifedipine and propranolol used in combination with diuretics for the treatment of hypertension.
Topics: Adult; Blood Pressure; Cholesterol, HDL; Clinical Trials as Topic; Diuretics; Double-Blind Method; D | 1987 |
Calcium-channel blockers for combined systemic hypertension and myocardial ischemia.
Topics: Angina Pectoris; Calcium Channel Blockers; Chronic Disease; Clinical Trials as Topic; Coronary Disea | 1987 |
Nifedipine monotherapy in the hypertensive elderly: a placebo-controlled clinical trial.
Topics: Aged; Aged, 80 and over; Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Edem | 1987 |
Acute natriuretic effect of nifedipine in hypertensive patients and normotensive controls--a proximal tubular effect?
Topics: Adult; Albuminuria; beta 2-Microglobulin; Blood Pressure; Body Water; Humans; Hypertension; Kidney T | 1987 |
A comparative study of atenolol/nifedipine and atenolol/diuretic in hypertension.
Topics: Atenolol; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fe | 1986 |
[Hypertensive crisis in hemodialysis treated with nifedipine].
Topics: Administration, Oral; Female; Humans; Hypertension; Male; Nifedipine; Renal Dialysis | 1987 |
Effect of nifedipine and mefruside on renal function and platelet function in hypertensive patients.
Topics: Blood Pressure; Diuretics; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Humans; Hy | 1987 |
Effect of sodium balance and calcium channel blocking drugs on blood pressure responses.
Topics: Adult; Angiotensin II; Blood Pressure; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; D | 1987 |
Monotherapy with the calcium channel antagonist nisoldipine for systemic hypertension and comparison with diuretic drugs.
Topics: Adult; Amiloride; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blin | 1987 |
[Modification of resting and effort hemodynamics in essential arterial hypertension using antihypertensive agents].
Topics: Acebutolol; Antihypertensive Agents; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; | 1987 |
Comparison of nifedipine, prazosin and hydralazine added to treatment of hypertensive patients uncontrolled by thiazide diuretic plus beta-blocker.
Topics: Adult; Aged; Atenolol; Bendroflumethiazide; Blood Pressure; Drug Administration Schedule; Drug Thera | 1987 |
Antihypertensive and metabolic effects of diltiazem and nifedipine.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Diltiazem; Double-Blind Method; Female; Heart Ra | 1986 |
[Prevention of hypertensive attacks after carotid surgery. The value of nifedipine and diltiazem].
Topics: Aged; Anesthesia Recovery Period; Anesthesia, General; Carotid Arteries; Diltiazem; Drug Evaluation; | 1986 |
Comparative trial of felodipine and nifedipine in refractory hypertension.
Topics: Aged; Ankle; Antihypertensive Agents; Blood Pressure; Body Weight; Calcium Channel Blockers; Clinica | 1985 |
Effects of felodipine on rest and exercise heart rate and blood pressure in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Bendroflumethiazide; Blood Pressure; Clinical Trials as Topic; Doubl | 1985 |
Effects of BAY l 5240, a fixed combination of low dose nifedipine and acebutolol on hypertension: comparison with standard dose nifedipine.
Topics: Acebutolol; Adult; Age Factors; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; | 1985 |
Are calcium antagonists cardioprotective?
Topics: Angina Pectoris; Animals; Blood Viscosity; Calcium Channel Blockers; Clinical Trials as Topic; Coron | 1985 |
Nicardipine hydrochloride in essential hypertension--a controlled study.
Topics: Adult; Age Factors; Calcium Channel Blockers; Clinical Trials as Topic; Female; Humans; Hypertension | 1985 |
Effect of nicardipine in elderly hypertensive patients.
Topics: Age Factors; Aged; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Female; Heart | 1985 |
Anti-hypertensive dose-response effects of nicardipine in stable essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as T | 1985 |
[Controlled study on the treatment of hypertension with verapamil in retard form].
Topics: Blood Pressure; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Electroc | 1985 |
Nifedipine in the treatment of essential hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Heart Rate; Humans; Hype | 1985 |
[Comparative, open and randomized evaluation of the antihypertensive activity of nifedipine and prazosin hydrochloride].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Heart Rat | 1985 |
Third-line therapy. A cautionary note.
Topics: Atenolol; Bendroflumethiazide; Captopril; Chlorthalidone; Female; Humans; Hypertension; Male; Methyl | 1985 |
Antihypertensive and metabolic effects of nifedipine and labetalol alone and in combination in primary hypertension.
Topics: Adult; Aged; Blood Glucose; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Ther | 1985 |
Antihypertensive, haemodynamic and metabolic effects of nifedipine slow-release tablets in elderly patients.
Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Double-Blind Method; Female; Hemodynami | 1985 |
Effects of a fixed combination of low dose nifedipine and acebutolol on essential hypertension: comparison with standard dose acebutolol.
Topics: Acebutolol; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; | 1985 |
[Immediate and long-term antihypertensive effects of nifedipine in mild and moderate hypertension].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Female; Furosemide; Hear | 1985 |
Felodipine in hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Felodipine; Female; Heart | 1985 |
The effects of nifedipine on platelet aggregation and plasma 6-keto-PGF1 alpha, and its interaction with indomethacin.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Animals; Blood Pressure; Clinical Trials as Topic; Double-Blind | 1985 |
The correlation between the hypotensive effect of increasing single doses of nifedipine tablets with its plasma concentration in patients with essential hypertension.
Topics: Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypertension; Male; M | 1985 |
[Hemodynamic effect of a calcium channel blocker agent (nifedipine) in arterial hypertension].
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Female; Heart Rate; Hemodynamics; Humans; Hypertens | 1985 |
Comparison of diltiazem and nifedipine for both angina pectoris and systemic hypertension.
Topics: Adult; Aged; Angina Pectoris; Benzazepines; Blood Pressure; Clinical Trials as Topic; Diltiazem; Dou | 1985 |
[Evaluation of the antihypertensive effect of capsule and tablet forms of nifedipine in moderate hypertension].
Topics: Aldosterone; Capsules; Clinical Trials as Topic; Double-Blind Method; Humans; Hypertension; Nifedipi | 1985 |
[Nifedipine as a vasodilator antihypertensive with a rapid action].
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Brain Diseases; Cardiomyopathies; Emergencies; Hem | 1985 |
[Comparative effects of nifedipine and indapamide in the treatment of arterial hypertension].
Topics: Adult; Blood Pressure; Body Weight; Clinical Trials as Topic; Diastole; Diuretics; Heart Rate; Human | 1985 |
[Antihypertensive effect of a new form of nifedipine compared to a beta-blocker during chronic administration].
Topics: Acebutolol; Adult; Aged; Blood Pressure; Body Weight; Clinical Trials as Topic; Female; Heart Rate; | 1985 |
Renal effects of nicardipine in patients with mild-to-moderate essential hypertension.
Topics: Adult; Calcium Channel Blockers; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertens | 1986 |
Acute diuretic/natriuretic properties of felodipine in man.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Diuresis; Felodipine; Female; Heart Rate; Huma | 1985 |
Ambulatory BP monitoring after acute administration of slow release nifedipine, alone or in combination with acebutolol, in systo-diastolic and in systolic hypertension.
Topics: Acebutolol; Adult; Aged; Ambulatory Care; Blood Pressure; Blood Pressure Determination; Humans; Hype | 1985 |
Slow-release nifedipine versus placebo in the treatment of arterial hypertension. A double blind ergometric evaluation of cardiac workload.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Exercise Test; Female; Hear | 1985 |
Blood pressure, heart rate and A-V conduction responses to nicardipine in hypertensive patients receiving atenolol.
Topics: Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart | 1985 |
Slow-release nifedipine as a single or additional agent in the treatment of essential hypertension--a placebo-controlled crossover study.
Topics: Adult; Aged; Body Weight; Delayed-Action Preparations; Double-Blind Method; Female; Heart Rate; Huma | 1985 |
Efficacy and safety of sublingual nifedipine in hypertensive emergencies.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Emergencies; Female; Humans; Hypertension; Male; | 1985 |
The pharmacodynamics and pharmacokinetics of a new calcium antagonist nisoldipine in normotensive and hypertensive subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Kinetics; Male; Nifedipine; N | 1985 |
1440 other studies available for nifedipine and Blood Pressure, High
| Article | Year |
|---|---|
Dihydropyrimidine calcium channel blockers. 4. Basic 3-substituted-4-aryl-1,4-dihydropyrimidine-5-carboxylic acid esters. Potent antihypertensive agents.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Crystallization; Hypertensio | 1992 |
Synthesis, calcium-channel-blocking activity, and antihypertensive activity of 4-(diarylmethyl)-1-[3-(aryloxy)propyl]piperidines and structurally related compounds.
Topics: Animals; Antihypertensive Agents; Aorta; Calcium; Calcium Channel Blockers; Hypertension; Male; Mole | 1991 |
A new class of calcium antagonists. 2. Synthesis and biological activity of 11-[[4-[4-(4-fluorophenyl)-1-piperazinyl]butyryl]amino]-6,11- dihydrodibenzo[b,e]-thiepin maleate and related compounds.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Chemical Phenomena; Chemistry; Chemistr | 1991 |
Antihypertensive dihydropyridines with 1,4,4-trisubstitution.
Topics: Animals; Antihypertensive Agents; Chemical Phenomena; Chemistry; Dihydropyridines; Hypertension; Mol | 1990 |
2-Ethynylbenzenealkanamines. A new class of calcium entry blockers.
Topics: Alkynes; Amines; Animals; Calcium Channel Blockers; Coronary Circulation; Guinea Pigs; Hypertension; | 1988 |
Synthesis and antihypertensive activity of substituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Biological Assay; Hypertension; Indicators and Reagen | 1983 |
Synthesis and pharmacological investigation of 3-(substituted 1-phenylethanone)-4-(substituted phenyl)-1, 2, 3, 4-tetrahydropyrimidine-5-carboxylates.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Edema; Hyper | 2009 |
Antihypertensive activity of newer 1,4-dihydro-5-pyrimidine carboxamides: synthesis and pharmacological evaluation.
Topics: Animals; Antihypertensive Agents; Desoxycorticosterone; Drug Evaluation, Preclinical; Hypertension; | 2010 |
Efficacy and Safety of Immediate-Release Nifedipine in Critically Ill Patients.
Topics: Antihypertensive Agents; Blood Pressure; Critical Illness; Humans; Hypertension; Hypotension; Nifedi | 2023 |
Gestational weight gain among gravidae with hypertension receiving labetalol versus nifedipine.
Topics: Antihypertensive Agents; Blood Pressure; Female; Gestational Weight Gain; Humans; Hypertension; Labe | 2022 |
Comparative effectiveness of generic nifedipine versus Adalat long-acting nifedipine for hypertension treatment: A multi-institutional cohort study.
Topics: Cohort Studies; Drugs, Generic; Humans; Hypertension; Nifedipine; Retrospective Studies | 2022 |
Comparative efficacy of generic nifedipine versus brand-name amlodipine for hypertension management in Taiwan.
Topics: Amlodipine; Calcium Channel Blockers; Drugs, Generic; Heart Failure; Humans; Hypertension; Ischemic | 2022 |
Antihypertensive drug prescription trends for pregnant women with hypertension in acute hospitals in Japan.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Drug Prescriptions; Female; Hospitals | 2022 |
Antihypertensive medicine use differs between Ghana and Nigeria.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihyperten | 2022 |
Race/ethnicity differences in response to acute antihypertensive treatment of peripartum severe hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Ethnicity; Female; Humans; Hydralazine; Hypertension; Labet | 2022 |
Postpartum Readmission for Hypertension After Discharge on Labetalol or Nifedipine.
Topics: Antihypertensive Agents; Cohort Studies; Female; Humans; Hypertension; Hypertension, Pregnancy-Induc | 2022 |
Trends in antihypertensive prescription for pregnant women with hypertension and their peripartum outcomes before and after label and guideline revisions in Japan.
Topics: Antihypertensive Agents; Cesarean Section; Drug Prescriptions; Female; Humans; Hydralazine; Hyperten | 2022 |
Delayed Decline of Cognitive Function by Antihypertensive Agents: A Cohort Study Linked with Genotype Data.
Topics: Adrenergic Antagonists; Adult; Aged; Amlodipine; Antihypertensive Agents; Apolipoprotein E4; Calcium | 2022 |
Postpartum medical management of hypertension and risk of readmission for hypertensive complications.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; Patien | 2023 |
Postpartum medical management of hypertension and risk of readmission for hypertensive complications.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; Patien | 2023 |
Postpartum medical management of hypertension and risk of readmission for hypertensive complications.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; Patien | 2023 |
Postpartum medical management of hypertension and risk of readmission for hypertensive complications.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Labetalol; Nifedipine; Patien | 2023 |
Association between clinical use of nifedipine and the risk of osteoporosis: a nationwide retrospective cohort study.
Topics: Calcium Channel Blockers; Cohort Studies; Female; Humans; Hypertension; Male; Nifedipine; Osteoporos | 2023 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; | 2023 |
Critical commentary on labetalol and nifedipine use in postpartum hypertension management.
Topics: Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Hypertension, Pregnancy-Induc | 2023 |
Reply to 'Critical commentary on labetalol and nifedipine use in postpartum hypertension management'.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Nifedipine; Postpartum Period | 2023 |
Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension.
Topics: Biphenyl Compounds; Delayed-Action Preparations; Diabetes Mellitus; Diabetic Nephropathies; Drug Com | 2023 |
Comparison of outcomes following intravenous magnesium compared with intravenous labetalol and oral nifedipine in 355 pregnant Han Chinese women with preeclampsia.
Topics: Antihypertensive Agents; Blood Pressure; East Asian People; Female; Humans; Hypertension; Infant, Ne | 2023 |
The Case | A 59-year-old woman with pressing thirst.
Topics: Amides; Calcium Channel Blockers; Female; Fumarates; Humans; Hypertension; Hyponatremia; Middle Aged | 2019 |
Letter to the Editor regarding research integrity.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pre-Eclampsia; Pregna | 2020 |
Identification of factors associated with delayed treatment of obstetric hypertensive emergencies.
Topics: Administration, Intravenous; Administration, Oral; Adult; After-Hours Care; Antihypertensive Agents; | 2020 |
Reply to letter regarding 'Methyldopa versus Nifedipine or no medication for treatment of chronic hypertension during pregnancy'.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Methyldopa; Nifedipine; Pre-Eclampsia; Pregna | 2020 |
Aqueous extract of oakmoss produces antihypertensive activity in L-NAME-induced hypertensive rats through sGC-cGMP pathway.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Arterial Pressure; B | 2021 |
Clinical efficacy of various anti-hypertensive regimens in hypertensive women of Punjab; a longitudinal cohort study.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Diuretics; | 2020 |
Engineering of Nanospheres Dispersed Microneedle System for Antihypertensive Action.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Cadmium Chloride; Chemi | 2020 |
Long-chain fatty dihydropyridines: Docking calcium channel studies and antihypertensive activity.
Topics: Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Calcium; Calcium Channel Blockers; C | 2020 |
Pharmacokinetic and Pharmacodynamic Studies of Nifedipine Loaded Microspheres for the Treatment of Hypertension.
Topics: Animals; Antihypertensive Agents; Horses; Hypertension; Microspheres; Nifedipine; Rats; Rats, Wistar | 2021 |
Calcium channel blockers, survival and ischaemic stroke in patients with dementia: a Swedish registry study.
Topics: Alzheimer Disease; Amlodipine; Brain Ischemia; Calcium Channel Blockers; Humans; Hypertension; Ische | 2021 |
Efficacy and safety outcomes of one generic nifedipine versus ADALAT long-acting nifedipine for hypertension management.
Topics: Drugs, Generic; Humans; Hypertension; Nifedipine; Retrospective Studies; Taiwan | 2020 |
Shunaoxin pills improve the antihypertensive effect of nifedipine and alleviate its renal lipotoxicity in spontaneous hypertension rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; China; Drugs, Chinese Herbal; Hypertension; Kidney | 2021 |
Cost-effectiveness analysis of combining traditional Chinese medicine in the treatment of hypertension: compound Apocynum tablets combined with Nifedipine sustained-release tablets vs Nifedipine sustained-release tablets alone.
Topics: Antihypertensive Agents; Apocynum; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Therapy, | 2020 |
Treatment of calcium channel blocker-induced gingival overgrowth without modifying medication.
Topics: Aged; Amlodipine; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Gingival Overgrowth; Humans; | 2021 |
Effectiveness and Tolerability of Nifedipine GITS in Patients with Chronic Kidney Disease and Uncontrolled Hypertension: A Prospective, Multicenter, Observational Study (ADRENAL).
Topics: Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Prospective Studies; Rena | 2021 |
Committee Opinion No. 692 Summary: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Committee Opinion No. 692: Emergent Therapy for Acute-Onset, Severe Hypertension During Pregnancy and the Postpartum Period.
Topics: Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Drug Administration Routes; E | 2017 |
Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Blood Pressure; Calcium Channel Blockers; Clarithr | 2017 |
Acute Generalized Exanthematous Pustulosis Secondary to Nifedipine.
Topics: Acute Generalized Exanthematous Pustulosis; Antihypertensive Agents; Calcium Channel Blockers; Femal | 2016 |
Influence of 3 calcium channel blockers on gingival overgrowth in a population of severe refractory hypertensive patients.
Topics: Adult; Aged; Amlodipine; Brazil; Calcium Channel Blockers; Felodipine; Female; Gingival Overgrowth; | 2018 |
Co-Amorphous Simvastatin-Nifedipine with Enhanced Solubility for Possible Use in Combination Therapy of Hypertension and Hypercholesterolemia.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Calorimetry, Differential Scanning; Drug Combinat | 2018 |
CRHR2 (Corticotropin-Releasing Hormone Receptor 2) in the Nucleus of the Solitary Tract Contributes to Intermittent Hypoxia-Induced Hypertension.
Topics: Amphibian Proteins; Animals; Autonomic Nervous System; Calcium; Calcium Channel Blockers; Hypertensi | 2018 |
Hemodynamic Response to Gabapentin in Conscious Spontaneously Hypertensive Rats.
Topics: Analgesics; Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Cha | 2018 |
Exaggerated blood pressure response to fasudil or nifedipine in hypertensive Ren-2 transgenic rats: role of altered baroreflex.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Baroreflex; Blood Pressure; Calcium Channel | 2019 |
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; | 2019 |
Nifedipine induced gingival enlargement in an edentulous patient: a case report with one year follow up.
Topics: Aged; Calcium Channel Blockers; Gingiva; Gingival Hyperplasia; Gingivectomy; Humans; Hypertension; M | 2018 |
ABCG2 c.421C>A polymorphism alters nifedipine transport to breast milk in hypertensive breastfeeding women.
Topics: Adult; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Feed | 2019 |
Oral regimen management of acute hypertension in pregnancy.
Topics: Antihypertensive Agents; Female; Humans; Hypertension; Labetalol; Methyldopa; Nifedipine; Pregnancy; | 2019 |
[Variability of the response of the microvascular bed to medicamental vasodilation in patients with arterial hypertension].
Topics: Female; Forearm; Humans; Hypertension; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; | 2012 |
Progression of coronary artery calcification is associated with long-term cardiovascular events in hypertensive adults.
Topics: Adult; Aged; Calcinosis; Cardiovascular Diseases; Coronary Artery Disease; Coronary Vessels; Disease | 2013 |
Olmesartan ameliorates urinary dysfunction in the spontaneously hypertensive rat via recovering bladder blood flow and decreasing oxidative stress.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Bl | 2014 |
Drugs for treating hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drugs, Generic; Humans; Hydrochlorothia | 2013 |
[The efficacy of antihypertension drugs and their combinations in the non-treated hypertension].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Drug Therapy, | 2013 |
Rutin and quercetin show greater efficacy than nifedipin in ameliorating hemodynamic, redox, and metabolite imbalances in sodium chloride-induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Antioxidants; Arterial Pressure; Biomarkers; Disease Models, Anima | 2014 |
Early treatment to prevent hypertension: a laudable goal.
Topics: Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Female; Humans; Hyperte | 2013 |
Differential regulation of atrial contraction by P1 and P2 purinoceptors in normotensive and spontaneously hypertensive rats.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Carbonyl Cyanide m-Chlorophenyl | 2014 |
Effects of 1,8-cineole on hypertension induced by chronic exposure to nicotine in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cyclohexanols; Eucalyptol; Eucalyptus; Hypertensio | 2014 |
Nifedipine-sensitive blood pressure component in hypertensive models characterized by high activity of either sympathetic nervous system or renin-angiotensin system.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Hypertension; Male; Nifed | 2014 |
Calcium oscillations in human mesenteric vascular smooth muscle.
Topics: Adolescent; Adult; Aged; Aniline Compounds; Boron Compounds; Calcium Signaling; Cell Membrane; Femal | 2014 |
Effect of antihypertensive treatments on insulin signalling in lympho-monocytes of essential hypertensive patients: a pilot study.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Bloc | 2014 |
Nifedipine-induced histological changes in the parotid glands of hypertensive rats.
Topics: Animals; Antihypertensive Agents; Body Weight; Disease Models, Animal; Hypertension; Male; Nifedipin | 2014 |
Alagebrium (ALT-711) improves the anti-hypertensive efficacy of nifedipine in diabetic-hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Drug Therapy, Com | 2014 |
Pathophysiological functions of adrenomedullin and natriuretic peptides in patients with primary aldosteronism.
Topics: Adrenalectomy; Adrenomedullin; Adult; Atrial Natriuretic Factor; Essential Hypertension; Female; Hum | 2015 |
Endothelin A receptor blocker atrasentan lowers blood pressure by the reduction of nifedipine-sensitive calcium influx in Ren-2 transgenic rats fed a high-salt diet.
Topics: Animal Feed; Animals; Antihypertensive Agents; Atrasentan; Blood Pressure; Calcium; Calcium Channels | 2015 |
Barnidipine real-life tolerability in arterial hypertension: results from the BASIC-HT study.
Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Medica | 2015 |
Papilledema in a Hypertensive Adult With Grade 4 Retinopathy.
Topics: Adolescent; Antihypertensive Agents; Calcium Channel Blockers; Enalapril; Follow-Up Studies; Humans; | 2015 |
Regulation of myogenic tone and structure of parenchymal arterioles by hypertension and the mineralocorticoid receptor.
Topics: Animals; Antihypertensive Agents; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels, L | 2015 |
Effectiveness of combination therapy with nifedipine GITS: a prospective, 12-week observational study (AdADOSE).
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Drug Therapy, Comb | 2015 |
Analysis of nifedipine in human plasma and amniotic fluid by liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetics in hypertensive pregnant women.
Topics: Adult; Amniotic Fluid; Antihypertensive Agents; Chromatography, High Pressure Liquid; Female; Humans | 2015 |
A 12-year-old boy with dyspnea, hypertension, hematuria, and proteinuria.
Topics: Child; Diagnosis, Differential; Dyspnea; Furosemide; Glomerulonephritis; Hematuria; Humans; Hyperten | 2015 |
Effects of late-onset and long-term captopril and nifedipine treatment in aged spontaneously hypertensive rats: Echocardiographic studies.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Drug Evaluati | 2015 |
Barnidipine ameliorates the vascular and renal injury in L-NAME-induced hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cytoprotection; Disease | 2015 |
Ca-channel blocker-induced gingival overgrowth that improved with non-surgical therapy during visiting care: a case report.
Topics: Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Debridement; Essential Hyperte | 2015 |
Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm, Abdominal; Calcium Channel | 2015 |
Ontogenetic changes in contribution of calcium sensitization and calcium entry to blood pressure maintenance of Wistar-Kyoto and spontaneously hypertensive rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arteries; Blood Pressure; Calcium; Calcium C | 2015 |
Metabolic approaches to antihypertensive treatment in diabetic patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Calcium | 2015 |
Abnormal uterine artery remodelling in the stroke prone spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Gestational Age; Hypertension; Nifedipine; | 2016 |
Vesicovascular reflexes in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Blood Vessels; Epinephrine; Hyper | 2016 |
Hypotensive and antihypertensive effects of a hydroalcoholic extract from Senecio nutans Sch. Bip. (Compositae) in mice: Chronotropic and negative inotropic effect, a nifedipine-like action.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Electrocardiogra | 2016 |
Pharmacokinetic-pharmacodynamic analyses of antihypertensive drugs, nifedipine and propranolol, in spontaneously hypertensive rats to investigate characteristics of effect and side effects.
Topics: Action Potentials; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Ca | 2016 |
Effect of bedtime dosing of barnidipine hydrochloride in non-dipper hypertensive patients with obstructive sleep apnoea not treated with continuous positive airway pressure.
Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bloc | 2016 |
Safety of Immediate-Release Nifedipine.
Topics: Aged; Arrhythmias, Cardiac; Calcium Channel Blockers; Drug Compounding; Female; Follow-Up Studies; H | 2016 |
Gene expression profiling of calcium-channel antagonists in the heart of hypertensive and normotensive rats reveals class specific effects.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Gene Expression Profiling; Gene Expression Regulation; | 2016 |
Role of acetazolamide and telmisartan/nifedipine-GITS combination in antagonizing the blood pressure rise induced by high altitude exposure.
Topics: Acetazolamide; Altitude; Altitude Sickness; Benzimidazoles; Benzoates; Blood Pressure; Gastrointesti | 2016 |
Role of nifedipine and hydrochlorothiazide in MAPK activation and vascular smooth muscle cell proliferation and apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Proliferation; Cells, Cultured; Extracellular Signal-Regulated MA | 2017 |
Replacement of Amlodipine and Lercanidipine by Barnidipine: Tolerability and Effectiveness in a Real-Life Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridine | 2017 |
Development and Characterization Pulsatile Microspheres of Nifedipine for Hypertension.
Topics: Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Compounding; Drug Delivery Systems; Hum | 2017 |
Endothelium-independent vasorelaxant activity of Trachyspermum ammi essential oil on rat aorta.
Topics: Animals; Aorta; Aorta, Thoracic; Apiaceae; Calcium; Calcium Channel Blockers; Cyclohexane Monoterpen | 2017 |
Hypertension and generalised tonic-clonic seizures occurring 41 days after elective caesarian section.
Topics: Adult; Cesarean Section; Eclampsia; Elective Surgical Procedures; Epilepsy, Generalized; Epilepsy, T | 2008 |
Late blood pressure reduction in SHR subjected to transient captopril treatment in youth: possible mechanisms.
Topics: Age Factors; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Press | 2008 |
Unusual case of recurrent renal artery stenosis: lessons to learn.
Topics: Adult; Angiography; Enalapril; Graft Occlusion, Vascular; Humans; Hypertension; Male; Nifedipine; Re | 2009 |
Klebsiella septicemia presenting as renal subcapsular abscess and hypertension in a neonate.
Topics: Female; Humans; Hypertension; Infant, Newborn; Kidney Diseases; Klebsiella Infections; Nifedipine; T | 2008 |
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, C | 2008 |
Nifedipine intake increases the risk for periodontal destruction in subjects with type 2 diabetes mellitus.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Calcium Channel Blockers; Cohort Studies; Cros | 2008 |
"Pulse" treatment with high-dose angiotensin blocker reverses renal arteriolar hypertrophy and regresses hypertension.
Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anim | 2009 |
A comparison of the effects of commercially available hawthorn preparations on calcium transients of isolated cardiomyocytes.
Topics: Animals; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Crataegus; Heart Failure; Herb-Drug | 2008 |
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydr | 2009 |
Is combined L- and T-channel blockade better than L-channel blockade in therapy?
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydr | 2009 |
Arg347Cys polymorphism of alpha1A-adrenoceptor gene is associated with blood pressure response to nifedipine GITS in Chinese hypertensive patients.
Topics: Aged; Asian People; Blood Pressure; Chromatography, High Pressure Liquid; Female; Genotype; Humans; | 2009 |
Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Collagen; Disease Models, Animal; Fibros | 2009 |
Non-surgical treatment of gingival overgrowth induced by nifedipine: a case report on an elderly patient.
Topics: Aged; Dental Prophylaxis; Dental Scaling; Follow-Up Studies; Gingival Hemorrhage; Gingival Overgrowt | 2010 |
Molecular mechanisms regulating urogenital expression of nitric oxide synthase in spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Channel Blockers; Doxazosin; Gene Expression; Gene Ex | 2009 |
[A case of Sjögren syndrome with nifedipine-induced pneumonia].
Topics: Female; Humans; Hypertension; Middle Aged; Nifedipine; Pneumonia; Sjogren's Syndrome; Vasodilator Ag | 2009 |
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcito | 2009 |
Rapid large artery remodeling following the administration and withdrawal of calcium channel blockers in spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Calcium Channel Blockers; Diltiazem; Endothelium; Hypertension; Male | 2009 |
Identification of potential therapeutic targets in hypertension-associated bladder dysfunction.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Doxazosin; Gene Expression; Gene Expression | 2010 |
Fatal lactic acidosis precipitated by nifedipine in a patient treated with disulfiram and antiretrovirals.
Topics: Acidosis, Lactic; Adult; Alcohol Deterrents; Alcoholism; Anti-Retroviral Agents; Antihypertensive Ag | 2009 |
Aripiprazole and hypertension in adolescents.
Topics: Adolescent; Antipsychotic Agents; Aripiprazole; Calcium Channel Blockers; Female; Humans; Hypertensi | 2009 |
Effect of chronic nifedipine treatment on blood pressure and adrenergic responses of isolated mesenteric artery in young rats with developing spontaneous hypertension.
Topics: Age Factors; Aging; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Calcium Channel Block | 2009 |
Antihypertensive role of glossopharyngeal nerve stimulation by nifedipine using as calcium channel blocking agent in hypertension: an experimental study.
Topics: Administration, Sublingual; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocke | 2009 |
Role of nifedipine-sensitive sympathetic vasoconstriction in maintenance of high blood pressure in spontaneously hypertensive rats: effect of Gi-protein inactivation by pertussis toxin.
Topics: Animals; Blood Pressure; Calcium Channels, L-Type; Calcium Signaling; GTP-Binding Protein alpha Subu | 2010 |
Effects of combination therapy with angiotensin II type I receptor blockers and calcium channel blockers on renal function in hypertensive patients/a retrospective, "real-world" comparative study.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Creatinine; Dih | 2010 |
Effects of ingestion of grapefruit juice or grapefruit on the hypotensive effect and plasma concentrations of dihydropyridine calcium antagonists (amlodipine and nifedipine): a case study.
Topics: Amlodipine; Beverages; Blood Pressure; Calcium Channel Blockers; Citrus paradisi; Cytochrome P-450 C | 2010 |
[Hypertensive urgency or hypertensive emergency?].
Topics: Adult; Antihypertensive Agents; Blood Pressure Determination; Emergencies; Female; Follow-Up Studies | 2010 |
Nifedipine activates PPARgamma and exerts antioxidative action through Cu/ZnSOD independent of blood-pressure lowering in SHRSP.
Topics: Anilides; Animals; Aorta; Blood Pressure; Calcium Channel Blockers; Cells, Cultured; Endothelium, Va | 2010 |
Therapeutically relevant blood pressure differences with two nifedipine (60 mg) osmotic delivery systems of differing design: three case reports.
Topics: Aged; Atrial Fibrillation; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Fe | 2010 |
Antihypertensive efficacy of Melothria maderaspatana leaf extract on sham-operated and uninephrectomized DOCA-salt hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Cucurbitac | 2010 |
[Effect of Jimaitong tablet combined with nifedipine on blood-pressure and mechanisms investigation in spontaneously hypertensive rats].
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Heart R | 2010 |
Prevention of hypertensive crises in rats induced by acute and chronic norepinephrine excess.
Topics: Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Infu | 2010 |
[CCB uptitration is superior to ARB uptitration in CKD patients who do not reach target blood pressure with ARB/CCB combined therapy].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Chro | 2010 |
Large-conductance Ca2+-activated K+ channel beta1-subunit knockout mice are not hypertensive.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Type; Heart; Hea | 2011 |
Preventive dietary potassium supplementation in young salt-sensitive Dahl rats attenuates development of salt hypertension by decreasing sympathetic vasoconstriction.
Topics: Animals; Blood Pressure; Dietary Supplements; Female; Hemodynamics; Hypertension; Nifedipine; Potass | 2011 |
Unexpected occurrence of adrenal Cushing's syndrome in a patient with systemic lupus erythematosus.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adult; Angiomyolipoma; Antihyperten | 2011 |
[Efficacy of sublingual nifedipine and intravenous urapidil for treatment of acute postoperative hypertension].
Topics: Administration, Sublingual; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Injections, | 2011 |
Effect of combination of edible oils on blood pressure, lipid profile, lipid peroxidative markers, antioxidant status, and electrolytes in patients with hypertension on nifedipine treatment.
Topics: Antioxidants; Blood Pressure; Calcium Channel Blockers; Electrolytes; Humans; Hypertension; Lipid Pe | 2011 |
Metabotropic regulation of RhoA/Rho-associated kinase by L-type Ca2+ channels: new mechanism for depolarization-evoked mammalian arterial contraction.
Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Coronary Vasos | 2011 |
Efficacy and tolerability of long-acting nifedipine GITS/OROS monotherapy or combination therapy in hypertensive patients: results of a 12-week international, prospective, multicentre, observational study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Delayed-Action Prepa | 2011 |
[Acute management at the rising of arterial pressure which is not menacing to a life].
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged; Angiotensin-Converting Enzyme Inhibitors; | 2011 |
Dutch guideline for the management of hypertensive crisis -- 2010 revision.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calc | 2011 |
Comparison of daily anti-hypertensive effects of amlodipine and nifedipine coat-core using ambulatory blood pressure monitoring - utility of "hypobaric curve" and "hypobaric area".
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulat | 2011 |
Assessment on antihypertensive effect and safety of nifedipine controlled-release tablet administered at 80 mg/day in practical clinic.
Topics: Adult; Age Factors; Aged; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pre | 2012 |
L/N-type calcium channel blocker suppresses reflex aldosterone production induced by antihypertensive action.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Block | 2012 |
Once daily nifedipine: the formulation dictates the pharmacokinetic characteristics and the therapeutic responses.
Topics: Calcium Channel Blockers; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug and Narcotic | 2012 |
Glycidipine, a promising hypotensive and cardioprotective agent.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiotonic Agents; Drug Combinations; Dru | 2011 |
Retinitis preceding systemic lupus erythematosus in absence of anti-phospholipid antibodies.
Topics: Adolescent; Antibodies, Antiphospholipid; Atenolol; Cyclophosphamide; Diagnosis, Differential; Drug | 2012 |
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulc | 2012 |
Clinical case report of long-term follow-up in type-2 diabetes patient with severe chronic periodontitis and nifedipine-induced gingival overgrowth.
Topics: Calcium Channel Blockers; Chronic Periodontitis; Diabetes Mellitus, Type 2; Gingival Overgrowth; Gly | 2012 |
[Broadened indications for the use of selective β-adrenoblockers].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Bisoprolol; Calcium Channel Blockers; Female; | 2012 |
Antihypertensive drugs and lip cancer in non-Hispanic whites.
Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hydrochlorothiazide; Hypertension; Lip Neoplas | 2012 |
Amlodipine in pediatric patient with uncontrolled multifactorial hypertension. Formulation of amlodipine oral suspension.
Topics: Administration, Oral; Amlodipine; Calcium Channel Blockers; Child, Preschool; Female; Humans; Hypert | 2012 |
Dual influence of spontaneous hypertension on membrane properties and ATP production in heart and kidney mitochondria in rat: effect of captopril and nifedipine, adaptation and dysadaptation.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Antihypertensive Agents; Blood Pressure; | 2012 |
Differential gene expression profiles in spontaneously hypertensive rats induced by administration of enalapril and nifedipine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Brain; Enalapril; Heart; Hydrogen Peroxide; Hypert | 2013 |
A novel dosing regimen for calcium infusion in a patient of massive overdose of sustained-release nifedipine.
Topics: Adult; Calcium; Calcium Channel Blockers; Calcium Gluconate; Female; Humans; Hypertension; Nifedipin | 2013 |
Cerebrovascular alterations in pressure and protein kinase C-mediated constriction in Dahl salt-sensitive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorders; Disease Models, Animal | 2002 |
Calcium channel blockers revisited.
Topics: Angina Pectoris; Antihypertensive Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; China; Cli | 2002 |
Calcium channel blocker on trial: hypertension specialists win landmark libel lawsuits against Canadian Broadcasting Corporation.
Topics: Calcium Channel Blockers; Canada; Drug and Narcotic Control; Drug Industry; Humans; Hypertension; Ni | 2002 |
Antihypertensive therapy, nifedipine, and autonomic dysreflexia.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Autonomic Dysreflexia; Calcium Ch | 2002 |
Generic substitution--is it safe in patients at high cardiovascular risk?
Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Drugs, Generic; Female; Humans; Hypertensio | 2002 |
Antiplatelet activity of semotiadil fumarate.
Topics: Adenosine Diphosphate; Adult; Amlodipine; Calcium Channel Blockers; Case-Control Studies; Collagen; | 2002 |
Ultrastructural changes in myocardium of hypertensive rats treated with nifedipine.
Topics: Animals; Heart; Heart Ventricles; Hypertension; Microscopy, Electron; Myocardium; Nifedipine; Rats; | 2002 |
"What goes up must immediately come down!" Which indication for short-acting nifedipine in children with arterial hypertension?
Topics: Adolescent; Adult; Blood Flow Velocity; Child; Humans; Hypertension; Nifedipine; Vasodilator Agents | 2003 |
The role of the critical event committee in a major cardiovascular outcome study.
Topics: Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; N | 2002 |
Nifedipine-induced changes in body composition in hypertensive patients at term.
Topics: Adult; Blood Pressure; Body Composition; Body Water; Calcium Channel Blockers; Electric Impedance; F | 2003 |
Depression--an adverse event with nifedipine.
Topics: Calcium Channel Blockers; Depression; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 2002 |
[Oral or sublingual nifedipine: utility and long-term effectiveness of medical education to decrease its use in increased blood pressure].
Topics: Administration, Oral; Administration, Sublingual; Drug Utilization; Education, Medical; Humans; Hype | 2003 |
Persistent lowering of arterial pressure after continuous and intermittent therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Drug The | 2003 |
Comparison of inhibitory effects of Y-27632, a Rho kinase inhibitor, in strips of small and large mesenteric arteries from spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Enzyme Inhibitors; Hypertension | 2003 |
Life-style and medication compliance in elderly patients.
Topics: Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Administration Schedule; Humans; | 1998 |
Effects of long-acting calcium channel antagonists on neurohumoral factors: comparison of nifedipine coat-core with amlodipine.
Topics: Aged; Aged, 80 and over; Aldosterone; Amlodipine; Blood Pressure; Calcium Channel Blockers; Chemistr | 2003 |
Experimental study of myocardial collagen during nifedipine therapy of arterial hypertension.
Topics: Animals; Calcium Channel Blockers; Collagen; Hypertension; Myocardium; Nifedipine; Rats; Rats, Inbre | 2003 |
Stroke development in stroke-prone spontaneously hypertensive rats alters the ability of cerebrovascular muscle to utilize internal Ca2+ to elicit constriction.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Disease Models | 2003 |
Administration of nifedipine CR immediately after awakening prevents a morning surge in hypertensive patients. Case report of three cases.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Calcium Channel Blockers; Circadian Rhythm; Delayed-Ac | 2003 |
[When hypertension becomes an emergency case: lower the blood pressure, but slowly!].
Topics: Administration, Oral; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Diagnosis, Diffe | 2003 |
[Heart rate variability in patients with hypertension and type 2 diabetes treated with long acting calcium antagonists].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bl | 2003 |
May we die twice?
Topics: Amiloride; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications | 2003 |
Expression of the nuclear factor-kappaB and proto-oncogenes c-fos and c-jun are induced by low extracellular Mg2+ in aortic and cerebral vascular smooth muscle cells: possible links to hypertension, atherogenesis, and stroke.
Topics: Animals; Aorta, Thoracic; Biomarkers; Calcium; Calcium Channel Blockers; Cardiovascular Diseases; Di | 2003 |
Inadvertent intravenous administration of a high dose of ephedrine.
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Ephedrine; Heart Rate; Humans; Hypertension | 2004 |
Inadequate control of blood pressure in Nigerians with diabetes.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care Facilities; Angiotensin-Converting Enzym | 2004 |
Treating high blood pressure in Africans with type 2 diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channe | 2004 |
Ocular ischemia associated with uncontrolled hypertension in lupus erythematosus.
Topics: Adult; Blood Pressure; Fluorescein Angiography; Humans; Hypertension; Ischemia; Lupus Erythematosus, | 2004 |
[Clinical features and up-to-date therapy of hypertensive emergencies].
Topics: Administration, Sublingual; Calcium Channel Blockers; Contraindications; Emergencies; Humans; Hypert | 2004 |
The safety and use of short-acting nifedipine in hospitalized hypertensive children.
Topics: Adolescent; Calcium Channel Blockers; Child; Child, Preschool; Female; Humans; Hypertension; Infant; | 2004 |
[Nifedipine GITS--clinical efficacy and effect on quality of life in elderly patients with hypertension].
Topics: Aged; Calcium Channel Blockers; Delayed-Action Preparations; Female; Humans; Hypertension; Male; Mid | 2004 |
Protection of blood-brain barrier breakdown by nifedipine in adrenaline-induced acute hypertension.
Topics: Albumins; Animals; Blood Pressure; Blood-Brain Barrier; Calcium Channel Blockers; Capillary Permeabi | 2004 |
Adverse events associated with aggressive treatment of increased blood pressure.
Topics: Administration, Oral; Aged; Aged, 80 and over; Brain Ischemia; Capsules; Chronic Disease; Female; He | 2004 |
Metabolism of the dihydropyridine calcium channel blockers mebudipine and dibudipine by isolated rat hepatocytes.
Topics: Angina Pectoris; Animals; Cell Culture Techniques; Half-Life; Hepatocytes; Hydroxylation; Hypertensi | 2004 |
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltia | 2005 |
Long-term treatment with nifedipine modulates procoagulant marker and C-C chemokine in hypertensive patients with type 2 diabetes mellitus.
Topics: Aged; Biomarkers; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Chemokine CCL2; Ch | 2005 |
Clarithromycin-nifedipine interaction as possible cause of vasodilatory shock.
Topics: Aged; Anti-Bacterial Agents; Antihypertensive Agents; Clarithromycin; Drug Synergism; Heart Block; H | 2005 |
Benefits and safety of long-acting calcium antagonists in coronary artery disease: the Action Trial.
Topics: Calcium Channel Blockers; Coronary Artery Disease; Humans; Hypertension; Nifedipine; Randomized Cont | 2005 |
Treatment of complicated and uncomplicated hypertension with nifedipine in Palestine.
Topics: Calcium Channel Blockers; Diabetes Complications; Female; Humans; Hypertension; Male; Middle East; N | 2005 |
Modulation of blood pressure, lipid profiles and redox status in hypertensive patients taking different edible oils.
Topics: Antihypertensive Agents; Blood Pressure; Dietary Fats, Unsaturated; Humans; Hypertension; Lipids; Mi | 2005 |
Ventricular arrhythmia following short-acting nifedipine administration.
Topics: Administration, Sublingual; Adult; Female; Humans; Hypertension; Nifedipine; Tachycardia, Ventricula | 2005 |
Hypertension in children with chronic renal failure.
Topics: Antihypertensive Agents; Blood Pressure; Child; Dihydralazine; Glomerular Filtration Rate; Humans; H | 2005 |
Effect of a nifedipine induced reduction in blood pressure on the association between ocular pulse amplitude and ocular fundus pulsation amplitude in systemic hypertension.
Topics: Aged; Blood Pressure; Elasticity; Eye; Female; Heart Rate; Humans; Hypertension; Intraocular Pressur | 2005 |
[Gynecomastia (of the adult)].
Topics: Calcium Channel Blockers; Diagnosis, Differential; Gynecomastia; Humans; Hypertension; Male; Middle | 2005 |
Nifedipine OROS in Chinese patients with hypertension--results of a post-marketing surveillance study in Taiwan.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; China; Delayed-Action Pr | 2005 |
Role of protein kinase C in Ca channel blocker-induced renal arteriolar dilation in spontaneously hypertensive rats--studies in the isolated perfused hydronephrotic kidney.
Topics: Angiotensin II; Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels; Dose-Respo | 2005 |
Nifedipine gastrointestinal therapeutic system--hypertension management to improve cardiovascular outcomes.
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Drug Therap | 2005 |
[Efficacy of and tolerance to combined therapy with dihydropyridine and non-dihydropyridine Ca antagonists in patients with moderate arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-R | 2005 |
Nifedipine enhances the cardioprotective effect of an angiotensin-II receptor blocker in an experimental animal model of heart failure.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Body Weight; C | 2005 |
Chronobiological analysis by ambulatory blood pressure monitoring of the hyperbaric and hypobaric indexes for evaluation of the antihypertensive effect of long-acting nifedipine.
Topics: Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Delayed-Action Preparations | 2005 |
Taking a bite out of nifedipine.
Topics: Acute Disease; Autonomic Dysreflexia; Contraindications; Drug Labeling; Humans; Hypertension; Nifedi | 2005 |
Diminished responses to nifedipine imply severe end-organ damage in spontaneously hypertensive rats.
Topics: Animals; Aorta; Baroreflex; Blood Pressure; Body Weight; Calcium Channel Blockers; Hypertension; Kid | 2005 |
Predictors of health-related quality of life in hypertensive recipients following renal transplantation.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Female; Health Status Ind | 2005 |
Impact of antihypertensive treatments on erectile responses in aging spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Apomorphine; Blood Pressure; Enalapril; Hydralazine; Hydroc | 2006 |
Nifedipine represses ion channels, transporters and Ca(2+)-binding proteins in hearts of spontaneously hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Calreticulin; Cytoskeletal Proteins; Gene Expression | 2006 |
Vasodilators in aortic regurgitation.
Topics: Antihypertensive Agents; Aortic Valve Insufficiency; Disease Progression; Enalapril; Humans; Hyperte | 2006 |
Blood pressure variability, baroreflex sensitivity and organ damage in spontaneously hypertensive rats treated with various antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Aorta; Atenolol; Baroreflex; Biphenyl Compounds; Blood Pressure; C | 2006 |
[Emergency checklist in hypertensive crisis].
Topics: Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Clonidine; Diuretic | 2006 |
Ambient particulate matter affects cardiac recovery in a Langendorff ischemia model.
Topics: Air Pollutants; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Coronary Circulation; | 2006 |
Effects of nine antihypertensive drugs on blood pressure variability in sinoaortic-denervated rats.
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Calcium Channel Blockers; Carotid Sinus; Cl | 2006 |
Hematuria in a patient with class IV lupus nephritis.
Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerula | 2006 |
The effect of ionizing radiation of 1,4-dihydropyridine derivatives in the solid state.
Topics: Calcium Channel Blockers; Dihydropyridines; Electron Spin Resonance Spectroscopy; Felodipine; Gamma | 2007 |
Effect of nifedipine on adiponectin in hypertensive patients with type 2 diabetes mellitus.
Topics: Adiponectin; Aged; Biomarkers; Calcium Channel Blockers; Diabetes Complications; Diabetes Mellitus, | 2007 |
Nifedipine-lopinavir/ritonavir severe interaction: a case report.
Topics: Acute Kidney Injury; Anti-HIV Agents; Drug Interactions; HIV Infections; Humans; Hypertension; Lopin | 2007 |
Increased wall tension in response to vasoconstrictors in isolated mesenteric arterial rings from patients with high blood pressure.
Topics: Adult; Aged; Aged, 80 and over; Diclofenac; Female; Humans; Hypertension; In Vitro Techniques; Male; | 2006 |
The effect of nifedipine on oral contraceptive-induced hypertension in rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Ethinyl Estradiol; Female; Hypertension; Natriure | 2006 |
Efficacy and safety of nifedipine GITS in Chinese patients with hypertension--a post-marketing surveillance study.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; China; Female; Humans; Hypertension; Male; Middle Ag | 2007 |
Efficacy and safety of nifedipine GITS in Asians with hypertension: results of a post-marketing surveillance study in China.
Topics: Asian People; Blood Pressure; Calcium Channel Blockers; China; Female; Humans; Hypertension; Male; M | 2007 |
The NAD(P)H oxidase inhibitor apocynin improves endothelial NO/superoxide balance and lowers effectively blood pressure in spontaneously hypertensive rats: comparison to calcium channel blockade.
Topics: Acetophenones; Animals; Blood Pressure; Calcium Channel Blockers; Endothelium, Vascular; Enzyme Inhi | 2007 |
Beneficial effects of the combination of nifedipine and losartan in hypertensive Dahl salt-sensitive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Calcium Channel Blockers; D | 2007 |
Nifedipine-sensitive noradrenergic vasoconstriction is enhanced in spontaneously hypertensive rats: the influence of chronic captopril treatment.
Topics: Adrenergic Agonists; Animals; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Ch | 2007 |
[Correction of ventricular late potentials with drug and non-drug methods in patients with essential hypertension].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Delayed-Action Prep | 2007 |
The effect of Ramadan fasting on ambulatory blood pressure in hypertensive patients using combination drug therapy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood P | 2008 |
Effect of pretreatment with atenolol and nifedipine on ZD6126-induced cardiac toxicity in rats.
Topics: Adrenergic beta-Antagonists; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Antineoplasti | 2007 |
Effect of nilvadipine on regional cerebral blood flow in a patient with early Alzheimer disease.
Topics: Aged, 80 and over; Alzheimer Disease; Antihypertensive Agents; Cerebrovascular Circulation; Cysteine | 2008 |
[A rare case of nifedipine bezoar].
Topics: Aged, 80 and over; Bezoars; Calcium Channel Blockers; Colon, Sigmoid; Female; Humans; Hypertension; | 2008 |
The dangers of immediate-release nifedipine in the emergency treatment of hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Chemistry, Pharmaceutical; Emergencies; Female; Humans; | 2008 |
Delayed effects of hypotensive drugs on structural characteristics of the renal glomerular system in hypertensive NISAG rats.
Topics: Animals; Antihypertensive Agents; Enalapril; Hypertension; Kidney Glomerulus; Losartan; Male; Nifedi | 2007 |
[Dynamics of parameters of 24-hour blood pressure monitoring and spiro-ergometric test in patients with arterial hypertension during treatment with long acting form of nifedipine].
Topics: Aged; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Delayed-Action Preparations; E | 2007 |
The T- and L-type calcium channel blocker (CCB) mibefradil attenuates leg edema induced by the L-type CCB nifedipine in the spontaneously hypertensive rat: a novel differentiating assay.
Topics: Animals; Antihypertensive Agents; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channe | 2008 |
Using low dose oral nifedipine to prevent cancellation of cataract surgery for patients with preoperative hypertension.
Topics: Blood Pressure; Cataract Extraction; Humans; Hypertension; Nifedipine; Preoperative Care; Vasodilato | 2009 |
Effects of antihypertensive drugs on capillary rarefaction in spontaneously hypertensive rats: intravital microscopy and histologic analysis.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; | 2008 |
[Clinical efficacy of antihypertensive therapy of pregnant women with arterial hypertension with long acting nifedipine and bisoprolol].
Topics: Adrenergic beta-Antagonists; Adult; Bisoprolol; Blood Pressure; Calcium Channel Blockers; Delayed-Ac | 2008 |
[Clinical efficacy of the use of prolonged nifedipine in patients with arterial hypertension and chronic obstructive lung disease].
Topics: Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dose-Response Relationship, D | 2008 |
A 40-year-old woman with diabetes contemplating pregnancy after gastric bypass surgery.
Topics: Adult; Antihypertensive Agents; Breast Feeding; Diabetes Mellitus, Type 2; Female; Gastric Bypass; G | 2008 |
Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Ty | 2008 |
Inhibition of vascular endothelial growth factor-a signaling induces hypertension: examining the effect of cediranib (recentin; AZD2171) treatment on blood pressure in rat and the use of concomitant antihypertensive therapy.
Topics: Angiogenesis Inhibitors; Animals; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Ca | 2008 |
Effects of nifedipine on the hypotensive actions of alpha 2-agonists in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Blood Pressure; Clonidine; Drug Interactio | 1984 |
Large arteries in hypertension: acute effects of a new calcium entry blocker, nitrendipine.
Topics: Adult; Arteries; Blood Pressure; Calcium Channel Blockers; Female; Forearm; Heart Rate; Humans; Hype | 1984 |
Nitrendipine: hemodynamic effects in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart; Hemodynamics; Hypertension | 1984 |
Nitrendipine reverses vasoconstriction and renal hemodynamic changes in experimental hypertension.
Topics: Angiotensin II; Animals; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Hyper | 1984 |
Renal effects of nitrendipine monotherapy in essential hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Calcium Channel Blockers; Cardiac Output; Epinephrine; Glome | 1984 |
Acute and long-term effects of nitrendipine on resting and exercise hemodynamics in essential hypertension.
Topics: Adult; Atenolol; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Female; Heart Rate; Hemod | 1984 |
Efficacy and safety of nitrendipine in patients with severe hypertension: a multiclinic study.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Heart Rate | 1984 |
Nitrendipine in hypertension that is difficult to control.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug | 1984 |
Antihypertensive therapy with the long-acting calcium antagonist nitrendipine.
Topics: Adult; Aged; Blood Pressure; Body Weight; Calcium Channel Blockers; Female; Heart Rate; Humans; Hype | 1984 |
The calcium channel blocker nitrendipine in single- and multiple-agent antihypertensive regimens: preliminary report of a multicenter study.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Body Weight; Calcium Channel Blockers; Drug Therapy, Combi | 1984 |
Long-term effectiveness of BAY e 5009-nitrendipine in the treatment of mild and moderate arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Mal | 1984 |
Calcium antagonists for antihypertensive baseline therapy. First International Nitrendipine Symposium. Interlaken, April 13-14, 1984.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Nitrendipine | 1984 |
Place of calcium antagonists in antihypertensive therapy: introduction and round-table discussion.
Topics: Blood Pressure; Calcium Channel Blockers; Diet, Sodium-Restricted; Diuretics; Humans; Hypertension; | 1984 |
Mode of antihypertensive action of nitrendipine.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Diet; Dihydralazine; Heart; Hypertension; H | 1984 |
Parallel reduction of calcium-influx-dependent vasoconstriction and platelet-free calcium concentration with calcium entry and beta-adrenoceptor blockade.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Aged; Blood Platelets; Blood Pressure; Calcium; Calc | 1984 |
Converting enzyme inhibition to identify and treat renin-mediated or sodium-volume related forms of increased peripheral resistance in hypertension and in congestive heart failure.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arterioles; Captopril; Enalapril; | 1983 |
'Calcium agonist' in salt-dependent hypertension: hints at calcium-mediated blood pressure increase.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
[Active calcium and sodium transport by cardiac plasma membranes in the genetically hypertensive rat].
Topics: Animals; Calcium; Calmodulin; Cell Membrane; Hypertension; In Vitro Techniques; Ion Channels; Male; | 1984 |
Effect of nifedipine and verapamil on alpha-receptor-activation in patients with essential hypertension.
Topics: Adult; Aged; Blood Platelets; Dose-Response Relationship, Drug; Drug Evaluation; Drug Interactions; | 1984 |
Drugs and the heart. III. Calcium antagonists.
Topics: Angina Pectoris; Aniline Compounds; Arrhythmias, Cardiac; Calcium; Cardiomegaly; Diuretics; Heart Di | 1980 |
Nifedipine.
Topics: Angina Pectoris; Calcium; Hemodynamics; Humans; Hypertension; Nifedipine; Pyridines | 1980 |
[Centra, peripheral, and volumetric hemodynamic changes in the treatment of essential hypertension with calcium antagonists and beta blockaders].
Topics: Adrenergic beta-Antagonists; Calcium; Female; Hemodynamics; Humans; Hypertension; Male; Nifedipine; | 1980 |
[The present status of treatment of hypertension (author's transl)].
Topics: Adrenergic beta-Antagonists; Captopril; Clonidine; Humans; Hypertension; Nifedipine; Prazosin | 1981 |
Long-term therapy of arterial hypertension with nifedipine given alone or in combination with a beta-adrenoceptor blocking agent.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; H | 1982 |
Calcium antagonists in hypertension.
Topics: Calcium; Calcium Channel Blockers; Cell Membrane; Hemodynamics; Humans; Hypertension; Nifedipine; Ve | 1982 |
Antihypertensive effects of nifedipine combined with cardioselective beta-adrenergic receptor antagonism by atenolol.
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Antihypertensive Agents; Atenolol; Blood Pressure; Dru | 1982 |
Evaluation of the chronotropic property of captopril in hypertensive patients.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Autonomic Nervous Syst | 1982 |
Felodipine, an arteriolar dilator with pronounced antihypertensive effect.
Topics: Antihypertensive Agents; Arterioles; Blood Pressure; Felodipine; Humans; Hypertension; Kidney; Male; | 1983 |
Nifedipine in the treatment of difficult hypertensives.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Dru | 1983 |
[Calcium antagonists in the treatment of chronic arterial hypertension and hypertensive crisis].
Topics: Acute Disease; Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hu | 1983 |
The use of nifedipine as third line therapy in the treatment of severe hypertension.
Topics: Adrenergic beta-Antagonists; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1983 |
Use of nifedipine as an adjunct to current antihypertensive therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hype | 1984 |
[Calcium antagonists in the therapy of hypertension].
Topics: Adrenergic beta-Antagonists; Calcium Channel Blockers; Diuretics; Drug Synergism; Headache; Humans; | 1984 |
Pressor response to beta-blocking drugs.
Topics: Adrenergic beta-Antagonists; Atenolol; Blood Pressure; Female; Humans; Hypertension; Isoproterenol; | 1984 |
Treatment with verapamil reduces blood pressure and tends to normalize vascular responsiveness and ion transport in the spontaneously hypertensive rat.
Topics: Animals; Aorta; Blood Pressure; Calcium; Hypertension; Male; Muscle Contraction; Muscle, Smooth, Vas | 1982 |
Effect of nifedipine on blood pressure and on intracellular calcium in arterial hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium; Calcium Channel Blockers; Creatinine; Erythrocytes; Female; Hu | 1982 |
Comparison of cardiovascular, renal, and humoral effects of acute administration of two calcium channel blockers in normotensive and hypertensive subjects.
Topics: Blood Pressure; Calcium Channel Blockers; Catecholamines; Heart Rate; Hemodynamics; Humans; Hyperten | 1982 |
Contrasting effects of nifedipine, captopril, and propranolol in normotensive and hypertensive subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Captopril; Humans; Hypertension; Male; Nifedipine; | 1982 |
Slow channel inhibitors verapamil and nifedipine in the management of hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Isometric Contraction | 1982 |
An oral calcium antagonist for treatment of hypertensive emergencies.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Clonidine; Emergencies; Female; Heart Rate; Humans; | 1982 |
Heterogeneity of systemic hemodynamic response to a new calcium entry blocker, nitrendipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Hemodynamics; Hypertension; Nifedipine; Nitrendip | 1982 |
[Use of nifedipine derivatives in treating ischemic heart disease patients].
Topics: Angina Pectoris; Cardiac Complexes, Premature; Chronic Disease; Coronary Disease; Dose-Response Rela | 1984 |
Cardiac rhythm in hypertension assessed through 24 hour ambulatory electrocardiographic monitoring. Effects of load manipulation with atenolol, verapamil, and nifedipine.
Topics: Adult; Atenolol; Cardiomegaly; Echocardiography; Electrocardiography; Female; Heart Conduction Syste | 1983 |
Assessment of left ventricular performance in patients with variable states of hypertrophy secondary to essential hypertension using a new load-independent index, E' max/V 100.
Topics: Adult; Aged; Cardiomegaly; Female; Heart; Hemodynamics; Humans; Hypertension; Isosorbide Dinitrate; | 1983 |
[Echocardiographic and arterial pressure changes after acute and prolonged (3 months) administration of nifedipine].
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Echocardiography; Edema; Heart; Humans; Hypertension; Leg | 1984 |
Left ventricular unloading with calcium antagonists.
Topics: Cardiac Output; Cardiomegaly; Drug Evaluation; Hemodynamics; Humans; Hypertension; Myocardial Contra | 1984 |
Regression of structural cardiovascular changes by antihypertensive therapy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Cardiovascular System; Circadian Rhy | 1984 |
Reversal of left ventricular hypertrophy and improvement of cardiac function in man by nifedipine.
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Cardiomegaly; Cardiomyopathy, Dilated; Cardiomyopathy, | 1984 |
Calcium channels in the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Diltiazem; Electric Conductivity; Heart; Hypertension; Ion Ch | 1981 |
[Effects of calcium antagonists (verapamil and nifedipine) on blood levels of calcium and cyclic AMP in humans].
Topics: Adult; Calcium; Coronary Disease; Cyclic AMP; Electrocardiography; Electrolytes; Female; Heart; Huma | 1981 |
Calcium channel blockers for cardiovascular disorders.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium; Calcium Channel Blockers; | 1982 |
Calcium channel blockers: a pathophysiologically based antihypertensive treatment concept for the future?
Topics: Calcium Channel Blockers; Humans; Hypertension; Ion Channels; Nifedipine; Vascular Resistance; Verap | 1982 |
Acute effects of the calcium antagonist, nifedipine, on blood pressure, pulse rate, and the renin-angiotensin-aldosterone system in patients with essential hypertension.
Topics: Adult; Age Factors; Aldosterone; Angiotensin I; Angiotensin II; Blood Pressure; Calcium; Heart Rate; | 1982 |
New antihypertensive drugs. Angiotensin converting enzyme inhibitors and calcium antagonists.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopr | 1984 |
The effect of nifedipine on arterial pressure and reflex cardiac control.
Topics: Adult; Blood Pressure; Blood Pressure Determination; Cold Temperature; Female; Forearm; Heart Rate; | 1983 |
[Clinical pharmacology of the newer antihypertensive agents].
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Captopril; Guanfacine; Guanidines | 1983 |
The acute response to nifedipine is related to pre-treatment blood pressure.
Topics: Adult; Age Factors; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipin | 1983 |
Prevention of spontaneous and glucocorticoid hypertension in rats by nisoldipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cortisone; Glucocorticoids; Hypertension; Male; N | 1983 |
Sympathetic nerve and hormonal responses to a single dose of nifedipine in patients with essential hypertension and normal subjects: comparison among renin-subgroups.
Topics: Adult; Aged; Aldosterone; Blood Pressure; Female; Hormones; Humans; Hypertension; Male; Middle Aged; | 1983 |
[Long-term effects of nifedipine on blood pressure, cardiac dynamics, and plasma renin activity in patients with essential hypertension].
Topics: Adult; Aged; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1983 |
Acute treatment of hypertension with nifedipine.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Reni | 1983 |
Nifedipine in the treatment of hypertension.
Topics: Absorption; Adult; Aged; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Drug | 1983 |
Altered pressor responses in long-term nitrendipine treatment.
Topics: Adult; Aged; Angiotensin II; Blood Pressure; Calcium; Creatinine; Double-Blind Method; Heart Rate; H | 1984 |
[Critical remarks on the therapy of hypertension].
Topics: Antihypertensive Agents; Diuretics; Emergencies; Humans; Hypertension; Nifedipine; Reference Standar | 1984 |
Use of calcium antagonists as monotherapy in the management of hypertension.
Topics: Calcium; Calcium Channel Blockers; Humans; Hypertension; Nicardipine; Nifedipine; Nitroprusside; Pra | 1984 |
Long acting nifedipine in the treatment of severe hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin; Sod | 1984 |
[Treatment of essential arterial hypertension with nifedipine: relation between changes of arterial pressure and plasma renin activity].
Topics: Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin; Time Factors | 1984 |
Nifedipine in hypertensive emergencies.
Topics: Adult; Emergencies; Female; Humans; Hypertension; Nifedipine; Pyridines | 1983 |
Nifedipine in hypertensive emergencies.
Topics: Adolescent; Child; Emergencies; Humans; Hypertension; Nifedipine; Pyridines | 1983 |
Calcium antagonists, nitrates, and new antianginal drugs.
Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Isosorbide Dinitrate; Lidoflazine; | 1983 |
Calcium antagonists in hypertension: relation to abnormal sodium transport.
Topics: Blood Pressure; Female; Humans; Hypertension; Leukocytes; Male; Middle Aged; Nifedipine; Potassium; | 1983 |
Acute hypotensive response to nifedipine added to prazosin in treatment of hypertension.
Topics: Adult; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Male; Nifedipine; Prazosin; Qui | 1983 |
Diabetogenic effects of nifedipine.
Topics: Aged; Blood Glucose; Diabetes Mellitus; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1984 |
Effects of nifedipine on pulmonary arterial hypertension in patients with respiratory insufficiency without acute failure.
Topics: Aged; Blood Pressure; Carbon Dioxide; Chronic Disease; Forced Expiratory Flow Rates; Heart Rate; Hum | 1984 |
[Clinical use of new antihypertensives].
Topics: Alkaloids; Antihypertensive Agents; Benzylisoquinolines; Captopril; Diazoxide; Diterpenes; Humans; H | 1984 |
[Antihypertensives and the prevention of development of genetic hypertension in the hypertensive SHR rat].
Topics: Animals; Antihypertensive Agents; Atenolol; Captopril; Cardiomegaly; Dihydralazine; Dose-Response Re | 1980 |
[The use of nifedipine (Corinfar) in hypertensive crises].
Topics: Adult; Aged; Blood Pressure; Brain Diseases; Cardiovascular Diseases; Female; Humans; Hypertension; | 1984 |
Haemodynamic effects of nicardipine hydrochloride. Studies during its use to control acute hypertension in anaesthetized patients.
Topics: Acute Disease; Adolescent; Adult; Aged; Anesthesia, General; Female; Hemodynamics; Humans; Hypertens | 1984 |
Differential influence of the calcium antagonist nitrendipine and the vasodilator hydralazine on normal and elevated blood pressure.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Heart Rate; Hydralazine; Hypertension; Nifedipine | 1984 |
Effect of nicardipine in a hypertensive patient with diabetes mellitus.
Topics: Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 1; Humans; Hypertension; Male; Mid | 1984 |
Acute effects of nifedipine in African hypertensives.
Topics: Adult; Black People; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Kenya; Middle A | 1984 |
[Calcium antagonists in the treatment of arterial hypertension. Attempt at a differential therapy].
Topics: Adult; Aged; Blood Pressure; Calcium; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination | 1984 |
Calcium entry blockers for the treatment of severe hypertension and hypertensive crisis.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Heart Ventr | 1984 |
[The hypertensive crisis].
Topics: Acute Disease; Calcium Channel Blockers; Clonidine; Coronary Disease; Diazoxide; Dihydralazine; Dilt | 1984 |
Nifedipine in the treatment of systemic hypertension.
Topics: Humans; Hypertension; Nifedipine | 1984 |
Chewing nifedipine to rapidly treat hypertension.
Topics: Administration, Oral; Adult; Aged; Capsules; Cheek; Dose-Response Relationship, Drug; Emergencies; F | 1984 |
[Immediate antihypertensive effect of nifedipine].
Topics: Adult; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension; Male; Middle | 1984 |
Specific HPLC assay for serum nifedipine.
Topics: Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Male; Nifedipine; Pharmaceutical | 1984 |
[Arrest of a sudden rise in arterial pressure with nifedipine (corinfar)].
Topics: Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation; Female; Humans; Hypertension; Mal | 1984 |
[Use of nifedipine in the treatment of hypertensive crisis].
Topics: Antihypertensive Agents; Humans; Hypertension; Nifedipine; Vasodilator Agents | 1984 |
[Hypertensive crisis: treatment of emergencies with nifedipine].
Topics: Antihypertensive Agents; Emergency Medical Services; Female; Humans; Hypertension; Male; Middle Aged | 1984 |
Treatment of normotensive and hypertensive patients with preterm labor using oral nifedipine, a calcium antagonist.
Topics: Adult; Female; Humans; Hypertension; Infant, Newborn; Nifedipine; Obstetric Labor, Premature; Pregna | 1984 |
[A short-term clinical observation during the treatment of essential hypertension by atenolol composite tablets].
Topics: Adult; Atenolol; Chlorthalidone; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; | 1984 |
Calcium channel blockers. New treatment for cardiovascular disease.
Topics: Adult; Angina Pectoris; Calcium; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; Cardiovascu | 1983 |
[Initial and chronic effect of nifedipine in hypertensive patients].
Topics: Blood Pressure; Female; Humans; Hypertension; Kallikreins; Male; Nifedipine; Potassium; Pulse; Sodiu | 1983 |
Hypotension induced changes in cerebral microflow and EEG and their pharmacological alterations.
Topics: Animals; Blood Pressure; Brain Ischemia; Cats; Cerebrovascular Circulation; Electroencephalography; | 1983 |
[Nifedipine--a new modality in the management of hypertension].
Topics: Humans; Hypertension; Nifedipine | 1984 |
[Effect of EG-1088, EG-626 and nifedipine on vascular lesions associated with hypertension and hyperlipidemia in stroke-prone spontaneously hypertensive rats (SHR-SP)].
Topics: Animals; Aorta; Arteries; Basilar Artery; Blood Pressure; Cerebral Arteries; Hyperlipidemias; Hypert | 1984 |
Calcium influx mediated vasoconstriction: studies in patients with mild and moderate essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged | 1983 |
Gingival hyperplasia caused by nifedipine--a preliminary report.
Topics: Aged; Coronary Artery Bypass; Female; Gingiva; Gingival Hyperplasia; Humans; Hypertension; Male; Mid | 1984 |
Nifedipine versus nitroprusside for controlling hypertensive episodes during coronary artery bypass surgery.
Topics: Adult; Aged; Coronary Artery Bypass; Ferricyanides; Hemodynamics; Humans; Hypertension; Intraoperati | 1984 |
Nifedipine in hypertensive emergencies of children.
Topics: Adolescent; Blood Pressure; Child; Combined Modality Therapy; Drug Evaluation; Emergencies; Female; | 1983 |
[Treatment of the crisis of arterial hypertension with nifedipine].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Fact | 1983 |
Emergency treatment of hypertensive crisis with sublingual nifedipine.
Topics: Administration, Oral; Aged; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Mouth Floo | 1983 |
[Use of sublingual nifedipine in the hypertensive crisis].
Topics: Aged; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1983 |
[Calcium antagonists: a potent vasodilatory principle and alternative basic antihypertensive therapy].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Vasodi | 1983 |
Acute treatment of hypertensive crisis with nifedipine.
Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1983 |
[Nifedipine: possible drug of choice in hypertensive emergencies].
Topics: Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1983 |
[Arterial hypertension with secondary hyperaldosteronism, reversible by nifedipine, in systemic scleroderma].
Topics: Aged; Female; Humans; Hyperaldosteronism; Hypertension; Nifedipine; Scleroderma, Systemic | 1983 |
[Different effect of nifedipine in normotensive and hypertensive individuals: a functional anomaly of vascular smooth muscle in essential hypertension?].
Topics: Adult; Age Factors; Aged; Blood Pressure; Calcium; Female; Humans; Hypertension; Male; Middle Aged; | 1983 |
[Long-term effectiveness of nifedipine combined with propranolol in the treatment of hypertension].
Topics: Adult; Aged; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle | 1983 |
The effect of a new calcium channel blocker nicardipine on 24-hour ambulatory blood pressure and the pressor response to isometric and dynamic exercise.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Iso | 1983 |
Haemodynamic effects of nifedipine in essential hypertension at rest and during exercise.
Topics: Adult; Blood Pressure; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1983 |
Antihypertensive effect of nifedipine and its relationship to severity of hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines; | 1983 |
Calcium channel blocking agents. Council on scientific affairs.
Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Asthma; Calcium Channel Blockers; Cardiomyopathy, Hy | 1983 |
Baroreflex setting and sensitivity after acute and chronic nicardipine therapy.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1984 |
[Nifedipine in hypertensive emergencies and severe hypertension].
Topics: Acute Disease; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Drug Therapy, Combination; F | 1984 |
Nifedipine in hypertension and heart failure.
Topics: Adult; Aged; Blood Pressure; Delayed-Action Preparations; Drug Therapy, Combination; Female; Heart F | 1984 |
Short-term effects of felodipine, a new dihydropyridine, in hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Evaluation; Felodipi | 1984 |
Treatment of severe pregnancy-associated hypertension with the calcium antagonist nifedipine.
Topics: Adolescent; Adult; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pilot Projects; Pregnan | 1984 |
Differential sensitivity of Dahl salt-sensitive and Dahl salt-resistant rats to the hypotensive action of acute nifedipine administration.
Topics: Animals; Blood Pressure; Diet; Drug Resistance; Hypertension; Male; Nifedipine; Rats; Sodium Chlorid | 1984 |
[Calcium antagonists in the management of hypertension].
Topics: Aged; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nicardipine; | 1984 |
Control of spontaneous and deoxycorticosterone-salt hypertension and polyuria by nitrendipine pellets.
Topics: Animals; Antihypertensive Agents; Body Weight; Desoxycorticosterone; Female; Hypertension; Nifedipin | 1984 |
Systemic and regional hemodynamics in normotensive and spontaneously hypertensive rats after slow-channel calcium blocker nitrendipine.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Heart Rate; Hemodynamics; Hyperte | 1984 |
Clinical and systemic hemodynamic effects of nitrendipine.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Volume; Cardiac Output; Dose-Response Re | 1984 |
Effect of pindolol and nifedipine alone and in combination on haemodynamic parameters/variables in essential hypertension.
Topics: Adult; Blood Pressure; Cardiac Output; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; | 1984 |
Antihypertensive and renal effects of nicardipine.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Headache; Humans; Hyper | 1984 |
Antihypertensive effect of nicardipine hydrochloride in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipin | 1982 |
Renal effects of acute calcium blockade with nifedipine in hypertensive patients receiving beta-adrenoceptor-blocking drugs.
Topics: Adult; Albuminuria; beta 2-Microglobulin; Blood Pressure; Female; Heart Rate; Humans; Hypertension; | 1982 |
Cerebral ischaemia after nifedipine treatment.
Topics: Aged; Arrhythmias, Cardiac; Female; Humans; Hypertension; Ischemic Attack, Transient; Male; Nifedipi | 1981 |
The long-term management of hypertension with verapamil.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Constipation; Female; Heart Rate; Hu | 1982 |
Nitrendipine and other calcium entry blockers (calcium antagonists) in hypertension.
Topics: Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Dogs; Gallopamil; Heart; Hypertension; M | 1983 |
Calcium channel blockers.
Topics: Angina Pectoris; Angina Pectoris, Variant; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem | 1983 |
Immediate hemodynamic effects of a new calcium-channel blocking agent (nitrendipine) in essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Female; Heart Rate; Hemodynamics; H | 1983 |
Role of calcium antagonists in the treatment of essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Catecholamines; Diltiazem; Female; | 1983 |
Therapeutic uses of calcium channel blockers.
Topics: Angina Pectoris; Anti-Arrhythmia Agents; Calcium Channel Blockers; Cardiovascular System; Diltiazem; | 1983 |
Nifedipine in combination therapy for resistant hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Humans; Hypertension; Middle Aged; | 1983 |
Hemodynamic study of nifedipine administration in hypertensive patients.
Topics: Adult; Blood Pressure; Cardiac Output; Double-Blind Method; Heart Rate; Hemodynamics; Humans; Hypert | 1983 |
Nifedipine tablets for systemic hypertension: a study using continuous ambulatory intraarterial recording.
Topics: Adult; Aged; Blood Pressure Determination; Circadian Rhythm; Drug Administration Schedule; Exercise | 1983 |
Binding of [3H]nitrendipine to heart and brain membranes from normotensive and spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Brain; Hypertension; Kinetics; Male; Membranes; Myocardium; Nifedipine; Nitr | 1983 |
Acute oral management of hypertension: blood pressure response to prazosin and nifedipine.
Topics: Blood Pressure; Humans; Hypertension; Hypotension, Orthostatic; Middle Aged; Nifedipine; Prazosin; P | 1983 |
[Sublingual nifedipine in the therapy of hypertensive crisis].
Topics: Acute Disease; Administration, Oral; Aged; Female; Humans; Hypertension; Male; Nifedipine; Pyridines | 1983 |
[Calcium antagonists in the treatment of arterial hypertension].
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Muscle, Smo | 1983 |
[Sublingual nifedipine in hypertension].
Topics: Administration, Oral; Adult; Aged; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Mi | 1983 |
Prevention of DOCA-salt hypertension with the calcium blocker nitrendipine.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Desoxycorticosterone; Fe | 1983 |
The response of forearm resistance vessels to dilator agents in patients with primary hypertension: use of nifedipine in long term therapy.
Topics: Forearm; Humans; Hypertension; Male; Nifedipine; Pyridines; Time Factors; Vascular Resistance; Vasod | 1983 |
The effect of nifedipine on arterial pressure and reflex cardiac control.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyri | 1983 |
Nifedipine tablets for hypertension: a study using continuous ambulatory intra-arterial recording.
Topics: Blood Pressure; Circadian Rhythm; Heart Rate; Humans; Hypertension; Monitoring, Physiologic; Nifedip | 1983 |
[Calcium antagonists. Concept and therapeutic applications].
Topics: Angina Pectoris; Angina Pectoris, Variant; Calcium Channel Blockers; Cardiomyopathy, Hypertrophic; C | 1982 |
Antihypertensive effect of KB-944, a new calcium antagonist, in conscious normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Benzothiazoles; Blood Pressure; Calcium Channel Blockers; Desoxyco | 1982 |
Prevention of hypertensive vasculopathy by nifedipine in salt-loaded Dahl rats.
Topics: Animals; Blood Pressure; Body Weight; Female; Hematocrit; Hypertension; Nifedipine; Pyridines; Rats; | 1982 |
[Efficacy of nifedipine in combination with propranolol in the therapy of primary arterial hypertension of moderate degree].
Topics: Drug Evaluation; Drug Therapy, Combination; Humans; Hypertension; Nifedipine; Propranolol | 1982 |
[Efficacy of nifedipine in combination with propranolol in the therapy of primary arterial hypertension of moderate degree].
Topics: Drug Therapy, Combination; Humans; Hypertension; Nifedipine; Propranolol | 1982 |
Nifedipine for rapid control of severe hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; | 1982 |
[Cardiovascular effects of nifedipine for systemic hypertension associated with aortocoronary bypass graft surgery (author's transl)].
Topics: Adult; Aged; Coronary Artery Bypass; Hemodynamics; Humans; Hypertension; Intraoperative Complication | 1981 |
Management of severe hypertension with nifedipine in combination with clonidine or propranolol.
Topics: Adult; Blood Pressure; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertens | 1980 |
[Effects of a calcium antagonist, nifedipine, on arterial pressure and plasma renin activity in subjects with essential arterial hypertension].
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyri | 1981 |
[New hypotensive drugs].
Topics: Antihypertensive Agents; Captopril; Drug Evaluation; Guanfacine; Guanidines; Humans; Hypertension; L | 1981 |
Ischemic ECG changes with initial nifedipine therapy of severe hypertension.
Topics: Coronary Disease; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1982 |
Effects of calcium-entry antagonists in hypertension.
Topics: Calcium; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Pyridines; Sodium; Verapamil | 1982 |
The use of nifedipine as a third-step agent in the treatment of refractory hypertension.
Topics: Adult; Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1982 |
[The effect of nifedipine as hypotensive agent in patients with ischemic cardiopathy (author's transl)].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Coronary Disease; Female; Hemodynamics; Humans; Hyper | 1982 |
[Treatment of hypertensive emergencies with nifedipine].
Topics: Adult; Aged; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1982 |
Alternatives to beta-blockade in therapy of hypertension with angina pectoris: role of nifedipine or of labetalol.
Topics: Angina Pectoris; Blood Pressure; Drug Therapy, Combination; Ethanolamines; Exercise Test; Hemodynami | 1982 |
Evidence of a shared mechanism of vasoconstriction in pulmonary and systemic circulation in hypertension: a possible role of intracellular calcium.
Topics: Blood Pressure; Calcium Channel Blockers; Cardiac Output; Humans; Hypertension; Male; Nifedipine; Pu | 1982 |
Inhibition of DOC-salt and adrenal-regeneration hypertension with the calcium blocker nifedipine.
Topics: Adrenal Glands; Adrenalectomy; Animals; Blood Pressure; Desoxycorticosterone; Female; Heart Rate; Hy | 1982 |
[Treatment of hypertensive crises with oral nifedipine].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Female; Humans; Hypertension; Male; Middle Aged; N | 1982 |
The immediate hypotensive effect of oral nifedipine.
Topics: Administration, Oral; Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1982 |
Nitrendipine increases sodium excretion in acutely saline-loaded rats.
Topics: Animals; Calcium Channel Blockers; Diuresis; Female; Hypertension; Natriuresis; Nifedipine; Nitrendi | 1982 |
[Effects of therapy with a association of nifedipine and atenolol in patients with systemic arterial hypertension and angina pectoris].
Topics: Adult; Angina Pectoris; Atenolol; Drug Therapy, Combination; Humans; Hypertension; Male; Middle Aged | 1982 |
[Nifedipine in single-dose treatment of arterial hypertension].
Topics: Administration, Oral; Adult; Ambulatory Care; Blood Pressure; Female; Humans; Hypertension; Male; Mi | 1982 |
[New aspects of the treatment of angina pectoris and hypertension. 2d Mediterranean symposium, Madrid, 19 and 20 September 1980].
Topics: Angina Pectoris; Calcium Channel Blockers; Hypertension; Nifedipine; Pyridines | 1982 |
[Effects of a nifedipine-acebutolol combination in the treatment of patients with essential arterial hypertension].
Topics: Acebutolol; Adult; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Midd | 1982 |
[Nifedipine in the treatment of hypertension].
Topics: Calcium Channel Blockers; Drug Therapy, Combination; Humans; Hypertension; Methyldopa; Muscle, Smoot | 1982 |
[Effects of nifedipine on hemodynamics during exercise in essential hypertension].
Topics: Administration, Oral; Adult; Aged; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1982 |
Acute and long-term hypotensive effects and plasma concentrations of nifedipine in patients with essential hypertension.
Topics: Adult; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyri | 1982 |
[Paradoxical effect of nifedipine. A case report].
Topics: Coronary Disease; Electrocardiography; Female; Humans; Hypertension; Middle Aged; Nifedipine; Pyridi | 1982 |
[Effect of antihypertensive therapy on the oxygen consumption of the myocardium. III. Verapamil and nifedipine].
Topics: Adult; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Myocardium; Nifedipine; Oxygen Consump | 1981 |
[Treatment of hypertensive crisis with nifedipine].
Topics: Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1981 |
[Hemodynamic effects and effects on the renin-angiotensin-aldosterone system of the combination of nifedipine and acebutolol in patients with essential hypertension].
Topics: Acebutolol; Adult; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Midd | 1981 |
Antihypertensive effects of the calcium antagonistic agent nifedipine.
Topics: Administration, Oral; Calcium Channel Blockers; Heart Rate; Humans; Hypertension; Nifedipine; Pyridi | 1982 |
Efficacy of sublingual nifedipine in the acute treatment of systemic hypertension.
Topics: Acute Disease; Adult; Blood Pressure; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Inj | 1981 |
Nifedipine in hypertension. Expanding applications of a new drug.
Topics: Antihypertensive Agents; Humans; Hypertension; Nifedipine; Pyridines | 1981 |
[Hemodynamic evaluation of nifedipine in hypertensive subjects].
Topics: Adult; Drug Evaluation; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1980 |
[Acute effects of nifedipine and verapamil on arterial pressure, at rest and during and after exercise in hypertensive patients].
Topics: Adult; Aged; Blood Pressure; Exercise Test; Female; Humans; Hypertension; Male; Middle Aged; Nifedip | 1980 |
Specific determination of plasma nicardipine hydrochloride levels by gas chromatography-mass spectrometry.
Topics: Animals; Dogs; Gas Chromatography-Mass Spectrometry; Humans; Hypertension; Nicardipine; Nifedipine; | 1981 |
Antihypertensive effects of nifedipine on conscious normotensive and hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hydralazine; Hypertension; Hypertensio | 1981 |
Treatment of severe hypertension and hypertensive emergency with nifedipine, a calcium antagonistic agent.
Topics: Administration, Oral; Adult; Aged; Calcium; Drug Synergism; Drug Therapy, Combination; Emergencies; | 1981 |
[The effect of nifedipin on blood pressure and systolic time intervals in hypertensives and normotensives (author's transl)].
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction | 1981 |
[Combined evaluation of the therapeutic activity of nifedipine in coronary insufficiency alone and with hypertension].
Topics: Adult; Aged; Blood Pressure; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Nife | 1980 |
[Effect of graduated doses of nifedipine on ADP-induced platelet aggregation].
Topics: Adenosine Diphosphate; Drug Interactions; Humans; Hypertension; Nifedipine; Platelet Aggregation; Py | 1980 |
Calcium antagonists.
Topics: Angina Pectoris; Calcium Channel Blockers; Cell Membrane; Diltiazem; Heart; Humans; Hypertension; Mu | 1980 |
Evidence that the increased calcium sensitivity of resistance vessels in spontaneously hypertensive rats is an intrinsic defect of their vascular smooth muscle.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium; Disease Models, Animal; Felodipine; Hyper | 1981 |
Hypotensive action of nifedipine (Ca2+-antagonist) and propranolol in acute trials and its long-term therapy of hypertensive coronary heart disease patients.
Topics: Antihypertensive Agents; Blood Pressure; Calcium; Coronary Disease; Drug Therapy, Combination; Human | 1981 |
[The influence of lowering of cardiac afterload on the cardiac function in hypertensive patients (author's transl)].
Topics: Heart; Humans; Hypertension; Nifedipine; Stroke Volume; Systole | 1980 |
[Rapid hypotensive effect of nifedipine aerosol (author's transl)].
Topics: Adult; Aerosols; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; | 1980 |
Calcium antagonist nifedipine normalizes high blood pressure and prevents mortality in salt-loaded ds substrain of Dahl rats.
Topics: Animals; Calcium; Female; Hypertension; Nifedipine; Pyridines; Rats; Rats, Inbred Strains; Sodium Ch | 1981 |
[Effects of intravenous nicardipine hydrochloride (YC 93), a calcium antagonist, on renal function (author's transl)].
Topics: Glomerular Filtration Rate; Humans; Hypertension; Injections, Intravenous; Kidney; Nicardipine; Nife | 1981 |
[Clinical experience with short-term and long-term administration of nifedipine in arterial hypertension].
Topics: Emergencies; Humans; Hypertension; Middle Aged; Nifedipine; Pyridines | 1981 |
[Acute administration of nifedipine in hypertensive crisis].
Topics: Acute Disease; Aged; Humans; Hypertension; Middle Aged; Nifedipine; Pyridines | 1981 |
Cardiovascular protection by Ca antagonists.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Coronary Vasospasm; Diltia | 1980 |
[Nifedipine in the therapy of secondary hypertension].
Topics: Adrenal Gland Neoplasms; Humans; Hyperaldosteronism; Hypertension; Hypertension, Renovascular; Nifed | 1981 |
[Sublingual nifedipine in hypertensive crises].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Female; Humans; Hypertension; Male; Middle Aged; N | 1981 |
Effect of calcium antagonist, nifedipine, on blood pressure of various hypertensive rats.
Topics: Animals; Blood Pressure; Calcium; Hypertension; Male; Nifedipine; Pyridines; Rats | 1980 |
Adverse interaction between nifedipine and beta-blockade.
Topics: Angina Pectoris; Atenolol; Drug Interactions; Drug Therapy, Combination; Humans; Hypertension; Hypot | 1980 |
Different antihypertensive effects of nifedipine in conscious experimental hypertensive and normotensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Heart Rate; Hydralazine; Hyp | 1980 |
[PO2 and PCO2 after nifedipine administered by the sublingual route in hypertensive patients (author's transl)].
Topics: Administration, Oral; Adult; Blood Gas Analysis; Drug Evaluation; Female; Hemodynamics; Humans; Hype | 1980 |
Increased function of voltage-dependent Ca++ channels and Ca(++)-activated K+ channels in resting state of femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
[The lipid peroxidation indices of hypertension patients undergoing combined therapy with anaprilin, korinfar and hypothiazide].
Topics: Adult; Antihypertensive Agents; Antioxidants; Drug Evaluation; Drug Therapy, Combination; Female; Hu | 1995 |
Cardiovascular morbidity and ECT.
Topics: Arrhythmias, Cardiac; Cardiovascular Diseases; Comorbidity; Depressive Disorder; Drug Therapy, Combi | 1995 |
Are calcium antagonists safe?
Topics: Contraindications; Humans; Hypertension; Nifedipine | 1995 |
Effect of the new calcium antagonist (+/-)-(R*)-3-[(R*)-1-benzyl-3- piperidyl] methyl 1,4-dihydro-2,6-dimethyl-4-(m-nitrophenyl)-3,5- pyridinedicarboxylate hydrochloride (KW-3049) on cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegal | 1993 |
Calcium channels in vitamin B6 deficiency-induced hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Antiischemic effects of nifedipine in isolated working heart preparations of healthy, diabetic, and hypertensive rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiac Output; Coronary Circulation; Diabetes | 1994 |
Angiotensin blockade or calcium antagonists improve endothelial dysfunction in hypertension: studies in perfused mesenteric resistance arteries.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; B | 1994 |
Tacrolimus (FK506)-induced nephrotoxicity in spontaneous hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arterioles; Blood Urea Nitrogen; Creatinine; Hypertension; Ki | 1994 |
Mechanism of action of the inhibitory effect of nifedipine on the growth of cultured aortic cells from spontaneously hypertensive and normotensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Nifedipine prevents renal injury in rats with chronic nitric oxide inhibition.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 1995 |
Transforming growth factor-beta 1 expression and phenotypic modulation in the kidney of hypertensive rats.
Topics: Actins; Animals; Blotting, Northern; Cell Division; Cilazapril; Gene Expression; Genetic Markers; Hy | 1995 |
Syntheses, calcium channel agonist-antagonist modulation activities, and voltage-clamp studies of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-pyridinylpyridine-5-carboxylate racemates and enantiomers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Bradycardia; | 1995 |
Increased sensitivity to inhibition by nifedipine of responses of the mesenteric artery bed of the SHRSP to noradrenaline is not dependent on alpha 1-adrenoceptor subtypes.
Topics: Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; An | 1995 |
Risks and benefits of calcium antagonists.
Topics: Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Meta-Analysis as Topic; Nifedipine | 1995 |
Effects of Ca-antagonists on oxidative susceptibility of low density lipoprotein (LDL).
Topics: Adult; Amlodipine; Apolipoproteins; Calcium Channel Blockers; Electrophoresis, Agar Gel; Fatty Acids | 1995 |
Elevated plasma atrial natriuretic peptide concentrations in hypertensive patients with acute myocardial infarction.
Topics: Acebutolol; Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiac Output, Low; Creatine Ki | 1995 |
Rare primary signet ring carcinoma of the pancreas.
Topics: Aged; Carcinoma, Signet Ring Cell; Fatal Outcome; Female; Female Urogenital Diseases; Humans; Hypert | 1995 |
Calcium antagonists in coronary artery disease and hypertension. Time for reevaluation?
Topics: Calcium Channel Blockers; Case-Control Studies; Coronary Disease; Diuretics; Dose-Response Relations | 1995 |
Are calcium antagonists safe?
Topics: Contraindications; Humans; Hypertension; Nifedipine | 1995 |
Are calcium antagonists safe?
Topics: Contraindications; Humans; Hypertension; Nifedipine | 1995 |
Are calcium antagonists safe?
Topics: Contraindications; Humans; Hypertension; Nifedipine | 1995 |
Severe rhabdomyolysis in a kidney-transplant recipient receiving intravenous nifedipine.
Topics: Adult; Creatinine; Follow-Up Studies; Humans; Hypertension; Injections, Intravenous; Kidney Transpla | 1995 |
Antihypertensive effects of AJ-2615, a new calcium antagonist with alpha 1-adrenergic blocking activity in experimental hypertensive animals.
Topics: Adrenergic alpha-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Bloc | 1993 |
Functional role of Ca(2+)-activated K+ channels in resting state of carotid arteries from SHR.
Topics: Animals; Calcium; Carotid Arteries; Charybdotoxin; Hypertension; Male; Nifedipine; Potassium; Potass | 1993 |
[Effects of slow-release nifedipine on hemodynamics and pharmacokinetics in elderly hypertensives].
Topics: Aged; Delayed-Action Preparations; Female; Hemodynamics; Humans; Hypertension; Male; Nifedipine | 1994 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, | 1994 |
Dihydropyridine calcium antagonists and the trough: peak ratio: focus on adverse effects.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Vasodilation | 1994 |
[Nilvadipine in the hypertensive elderly. Risk factor for cerebral insufficiency. Study report].
Topics: Aged; Antihypertensive Agents; Brain; Calcium Channel Blockers; Cerebrovascular Circulation; Humans; | 1993 |
Hereditary proctalgia fugax and constipation: report of a second family.
Topics: Adult; Aged; Anal Canal; Constipation; Family; Female; Humans; Hypertension; Hypertrophy; Male; Midd | 1995 |
The difference in nifedipine sensitivity between hypertensive and normotensive rat aortae is dependent on age.
Topics: Adrenergic alpha-Antagonists; Aging; Animals; Aorta, Thoracic; Clonidine; Dioxanes; Hypertension; In | 1995 |
Arterial hemodynamics in human hypertension. Effects of the calcium channel antagonist nifedipine.
Topics: Adult; Arteries; Compliance; Female; Hemodynamics; Humans; Hypertension; Male; Nifedipine | 1995 |
Effects of angiotensin-converting enzyme inhibitors, Ca2+ channel antagonists, and alpha-adrenergic blockers on glucose and lipid metabolism in NIDDM patients with hypertension.
Topics: Adrenergic alpha-Antagonists; Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood | 1995 |
[Gingival hyperplasia induced by amlodipine].
Topics: Adult; Amlodipine; Calcium Channel Blockers; Gingival Hyperplasia; Humans; Hypertension; Male; Nifed | 1995 |
Quality of life in hypertension.
Topics: Angiotensin-Converting Enzyme Inhibitors; Humans; Hypertension; Lisinopril; Nifedipine; Patient Comp | 1994 |
Proteinuria in essential hypertension.
Topics: Adult; Aged; Colorimetry; Creatinine; Drug Combinations; Enalapril; Humans; Hypertension; Middle Age | 1994 |
Regression of left ventricular hypertrophy with long-term treatment of nifedipine in systemic hypertension.
Topics: Adult; Aged; Blood Pressure; Echocardiography; Female; Heart Rate; Humans; Hypertension; Hypertrophy | 1994 |
Body fat as a predictor of the antihypertensive effect of nifedipine.
Topics: Adipose Tissue; Adult; Aged; Aged, 80 and over; Blood Pressure; Female; Humans; Hypertension; Least- | 1995 |
Beta-adrenergic receptor antagonist antihypertensive medications impair arousal-induced modulation of working memory in elderly humans.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitor | 1994 |
[Calcium antagonists as the initial monotherapy in arterial hypertension].
Topics: Adult; Aged; Humans; Hypertension; Middle Aged; Nifedipine; Verapamil | 1993 |
Impairement of endothelium-dependent relaxation in chronic two-kidney, one clip hypertensive rats.
Topics: Acetylcholine; Animals; Constriction; Disease Models, Animal; Hypertension; In Vitro Techniques; Mal | 1994 |
Atrial fibrillation with hypertensive crisis.
Topics: Atrial Fibrillation; Electrocardiography; Furosemide; Humans; Hypertension; Male; Middle Aged; Nifed | 1994 |
[Therapy of arterial hypertension associated with acute stroke. Current trends and problems].
Topics: Acute Disease; Aged; Antihypertensive Agents; Blood Pressure Monitors; Cerebral Hemorrhage; Cerebrov | 1994 |
Experimental vasoprotection by calcium antagonists against calcium-mediated arteriosclerotic alterations.
Topics: Adult; Aged; Aged, 80 and over; Animals; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cells, | 1994 |
The use of nifedipine as first-line hypotensive therapy in gestational hypertension.
Topics: Adult; Female; Gestational Age; Humans; Hypertension; Infant, Newborn; Nifedipine; Pre-Eclampsia; Pr | 1994 |
The interaction of the calcium channel blockers verapamil and nifedipine with cyclosporin A in pediatric renal transplant patients.
Topics: Adolescent; Child; Child, Preschool; Cyclosporine; Drug Interactions; Graft Rejection; Half-Life; Hu | 1994 |
Reversible hyperkalemia during antihypertensive therapy in a hypertensive diabetic patient with latent hypoaldosteronism and mild renal failure.
Topics: Aged; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Furos | 1994 |
Atrial natriuretic peptide and cyclic guanosine-3'5'-monophosphate in hypertensive pregnancy and during nifedipine treatment.
Topics: Administration, Oral; Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Female; Humans; | 1994 |
Arterial smooth muscle responses in adult and moderately aged spontaneously hypertensive rats.
Topics: Aging; Aminoquinolines; Animals; Blood Platelets; Calcium; Endothelium, Vascular; Hypertension; Lymp | 1994 |
Nifedipine aggravates cyclosporine A-induced gingival hyperplasia.
Topics: Adolescent; Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Gingival Hyperplas | 1994 |
Nifedipine reduces pressor responsiveness to angiotensin II in pregnant women.
Topics: Adult; Angiotensin II; Blood Pressure; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnanc | 1994 |
Influence of long-term treatment with nifedipine on blood pressure, left ventricular mass and cardiac arrhythmias in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Aging; Arrhythmias, Cardiac; Blood Pressure; Cardiac Output; Circadian Rhyt | 1994 |
A new preparation of nifedipine for sublingual application in hypertensive urgencies.
Topics: Administration, Sublingual; Adult; Aerosols; Aged; Blood Pressure; Emergencies; Female; Humans; Hype | 1994 |
[Effect of nifedipine on proximal tubular function in patients with essential hypertension].
Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Kidney Tubules; Male; Nifedipine | 1994 |
Antihypertensive treatment in patients with a history of accelerated malignant hypertension, with special reference to clinical decision-making in changing treatment.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Drug Therapy, Combination; Female; | 1994 |
Effect of nifedipine on coronary capillary geometry in normotensive and hypertensive rats.
Topics: Animals; Capillaries; Coronary Vessels; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Rats | 1994 |
[Effect of nifedipine and enalapril on cardiac autonomic activity in elderly hypertensive patients].
Topics: Adult; Aged; Aged, 80 and over; Autonomic Nervous System; Enalapril; Female; Heart Rate; Humans; Hyp | 1994 |
Treating hypertension after stroke.
Topics: Administration, Oral; Cerebrovascular Disorders; Deglutition; Humans; Hypertension; Nifedipine | 1994 |
Case management in cerebral revascularization.
Topics: Aged; Aged, 80 and over; Angioplasty; Blood Vessel Prosthesis; Cerebral Revascularization; Cerebrova | 1994 |
Nifedipine and acute renal failure.
Topics: Acute Kidney Injury; Aged; Humans; Hypertension; Lung Diseases, Obstructive; Male; Nifedipine | 1993 |
Effect of nilvadipine on the development of neurological deficits in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Disorders; Eating; Hypertension; Male; Nifedipine | 1994 |
Verapamil and nifedipine in combination for the treatment of hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Drug Therapy, Combination; Edema; Female | 1994 |
[Relationship of the renin-angiotensin-aldosterone system with auricular natriuretic factor in its response to the action of thiazide diuretics and to nifedipine, a sustained-release calcium antagonist].
Topics: Aldosterone; Amiloride; Animals; Ants; Blood Pressure; Delayed-Action Preparations; Female; Heart Ra | 1994 |
Erythrocyte sodium cannot predict hypotensive effects of calcium channel blockers.
Topics: Age Factors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Erythrocytes; Female | 1993 |
[A method for determining individual nifedipine sensitivity in treating hypertension patients].
Topics: Adenosine Diphosphate; Adult; Drug Evaluation; Drug Tolerance; Humans; Hypertension; Male; Middle Ag | 1993 |
Attenuation of hypertensive-induced pulsus alternans by nifedipine and nitroglycerin.
Topics: Administration, Sublingual; Aged; Aortic Valve Stenosis; Atrial Fibrillation; Blood Pressure; Cardia | 1994 |
Tissue plasminogen activator in saliva of hypertensives treated with angiotensin converting enzyme inhibitors or calcium antagonists.
Topics: Adult; Aged; Blood Pressure; Enalapril; Female; Fibrinolysis; Humans; Hypertension; Male; Middle Age | 1993 |
[Effective and simple treatment of hypertension. Better compliance with slow-release nifedipin].
Topics: Animals; Humans; Hypertension; Nifedipine; Patient Compliance | 1994 |
[Renal insufficiency due to captopril in one patient with Burkitt's lymphoma].
Topics: Burkitt Lymphoma; Captopril; Child; Humans; Hypertension; Kidney; Kidney Neoplasms; Male; Neoplasm S | 1993 |
Effects of dihydropyridines on cerebral blood vessels.
Topics: Administration, Oral; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascu | 1993 |
The combination of magnesium sulphate and nifedipine: a cause of neuromuscular blockade.
Topics: Adult; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Magnesium Sulfate | 1994 |
Left ventricular function of the heart regressed by nifedipine in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Hemodynamics; Hypertension; Hypertrophy, Left Ventricular; Male; Nifedipine | 1994 |
Enhanced vascular reactivity to mastoparan, a G protein activator, in genetically hypertensive rats.
Topics: Animals; Blood Vessels; Ethylmaleimide; GTP-Binding Proteins; Hypertension; In Vitro Techniques; Ind | 1994 |
[The clofelin and nifedipine treatment of hypertensive crises in elderly patients].
Topics: Aged; Chronic Disease; Clonidine; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertens | 1993 |
[Left ventricular function in patients with arterial hypertension during the performance of acute drug tests with captopril and nifedipine].
Topics: Adult; Captopril; Drug Evaluation; Heart Function Tests; Humans; Hypertension; Hypertrophy, Left Ven | 1993 |
Acute antihypertensive effects of the new generation calcium antagonist 3-pyridine carboxylic acid 5-[(cyclopropylamino)-carbonyl]-1,4-dihydro-2,6-dimethyl-4-(2-nitrophen yl) octyl ester on conscious spontaneously hypertensive rats and renal hypertensive
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dose-R | 1993 |
Severe hypotension and fetal distress following sublingual administration of nifedipine to a patient with severe pregnancy induced hypertension at 33 weeks.
Topics: Adult; Female; Fetal Distress; Humans; Hypertension; Hypotension; Nifedipine; Pregnancy; Pregnancy C | 1993 |
Concentration-dependent effects of insulin on Ca2+ influx in vascular smooth muscle cells of normotensive and spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Hypertension; I | 1993 |
[Platelet calcium influx and changes of phosphatidyl inositol].
Topics: Adult; Blood Platelets; Calcium-Transporting ATPases; Female; Humans; Hypertension; Male; Middle Age | 1993 |
[A study on the dynamic effect of nifedipine on red blood cell cytoplasmic free calcium in hypertensive patients].
Topics: Adult; Aged; Calcium; Cytoplasm; Erythrocytes; Female; Humans; Hypertension; Male; Middle Aged; Nife | 1993 |
Nuclear imaging study of nifedipine induced modulations of central haemodynamics in severe hypertension with and without coronary artery disease.
Topics: Administration, Sublingual; Aged; Cardiac Output; Coronary Disease; Female; Gated Blood-Pool Imaging | 1993 |
[Anesthesia for renal transplantation: continuous neuromuscular blockade with atracurium and the management of intraoperative hypertension with nifedipine].
Topics: Adult; Anesthesia; Atracurium; Female; Fentanyl; Humans; Hypertension; Intraoperative Complications; | 1993 |
Effect of captopril on vasoconstriction and Ca2+ fluxes in aortic smooth muscle.
Topics: Analysis of Variance; Angiotensin II; Animals; Aorta, Thoracic; Bradykinin; Calcium; Calcium Channel | 1993 |
Rectal nifedipine for the management of intraoperative hypertension.
Topics: Administration, Rectal; Adolescent; Adult; Female; Hemodynamics; Humans; Hypertension; India; Intrao | 1993 |
Cardiac structural remodelling after treatment of spontaneously hypertensive rats with nifedipine or nisoldipine.
Topics: Animals; Cell Size; Fibrosis; Heart; Hypertension; Male; Myocardium; Nifedipine; Nisoldipine; Organ | 1993 |
Hypertension and hypoparathyroidism--narrowed therapeutic safety with nifedipine.
Topics: Adult; Contraindications; Female; Humans; Hypertension; Hypocalcemia; Hypoparathyroidism; Hypotensio | 1993 |
Nifedipine news.
Topics: Absorption; Administration, Oral; Emergencies; Humans; Hypertension; Nifedipine | 1993 |
Effects of semotiadil fumarate, a novel calcium antagonist, on blood pressure and heart rate in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Hear | 1993 |
Alterations in cardiac myosin isozymes associated with aging and chronic hypertension: their modulation with nifedipine.
Topics: Aging; Animals; Chronic Disease; Electrophoresis, Polyacrylamide Gel; Hypertension; Hypertrophy, Lef | 1993 |
[A reduction of left ventricular hypertrophy and an improvement in diastolic function after therapy with nifedipine retard in patients with hypertensive cardiopathy].
Topics: Adult; Aged; Delayed-Action Preparations; Diastole; Drug Evaluation; Echocardiography; Echocardiogra | 1993 |
Nifedipine overdose in a 70 year old man.
Topics: Aged; Bradycardia; Drug Overdose; Humans; Hypertension; Hypotension; Male; Nifedipine; Pulmonary Ede | 1993 |
Skin flux and the venoarteriolar response in essential hypertension.
Topics: Adult; Female; Humans; Hypertension; Male; Microcirculation; Middle Aged; Nifedipine; Regional Blood | 1993 |
Changes in vascular smooth muscle function in hypertension.
Topics: Animals; Arginine Vasopressin; Blood Pressure; Cholera Toxin; Hypertension; Male; Muscle, Smooth, Va | 1993 |
[Reproducibility of heart rate variability measurements in repeated 24-hour long-term ECG registration].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Diltiazem; Electrocardiography, Ambulatory; F | 1993 |
Severe hypotension with enalapril.
Topics: Enalapril; Humans; Hypertension; Hypotension; Nifedipine | 1993 |
Role of left ventricular regional nonuniformity in hypertensive diastolic dysfunction.
Topics: Adult; Analysis of Variance; Chi-Square Distribution; Diastole; Drug Evaluation; Echocardiography; F | 1993 |
[Effects of sublingual nifedipine on the velocity of pulse wave evaluated by Doppler echocardiography of the thoracic aorta].
Topics: Administration, Sublingual; Aorta, Thoracic; Depression, Chemical; Echocardiography, Doppler; Female | 1993 |
In vitro and in vivo electrocardiographic evaluation of the novel calcium antagonist monatepil on cardiac conduction system.
Topics: Anesthesia; Animals; Blood Pressure; Bundle of His; Calcium Channel Blockers; Dibenzothiepins; Dilti | 1993 |
Pharmacokinetic and pharmacodynamic comparisons of oral and sublingual nifedipine in hypertensive Mexican patients.
Topics: Administration, Oral; Administration, Sublingual; Aged; Blood Pressure; Female; Heart Rate; Humans; | 1993 |
Functional alterations in the aorta of the spontaneously hypertensive rat: pharmacological assessment with cyclopiazonic acid.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channels; Endoplasmic Reticulum; Hypertension; Indoles; M | 1993 |
Treatment of hypertension in acrodynia.
Topics: Acrodynia; Adolescent; Child; Female; Humans; Hypertension; Male; Nifedipine | 1993 |
[Clinical study of total intravenous anesthesia with droperidol, fentanyl and ketamine--effects of nicardipine, diltiazem and nifedipine on intraoperative hypertension].
Topics: Anesthesia, Intravenous; Calcium Channel Blockers; Diltiazem; Droperidol; Female; Fentanyl; Humans; | 1993 |
Bezafibrate-induced neutropenia.
Topics: Bezafibrate; Dyspnea; Female; Flushing; Humans; Hyperlipidemias; Hypertension; Leukocyte Count; Midd | 1993 |
Gingival hyperplasia in renal allograft recipients receiving cyclosporin-A and calcium antagonists.
Topics: Adult; Cross-Sectional Studies; Cyclosporine; Dental Calculus; Dental Plaque Index; Diltiazem; Drug | 1993 |
Response to "Monoamine oxidase inhibitors and hypertension".
Topics: Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hypertensi | 1993 |
[Glyco-lipid changes in hypertensive diabetic patients undergoing treatment with nifedipine and captopril].
Topics: Adult; Blood Glucose; Captopril; Cholesterol; Diabetes Complications; Diabetes Mellitus; Follow-Up S | 1993 |
Hypertension after renal transplantation.
Topics: Adult; Analysis of Variance; Antihypertensive Agents; Creatinine; Cyclosporine; Female; Graft Reject | 1993 |
Decongestant-induced hypertensive crisis.
Topics: Adult; Charcoal; Chlorpheniramine; Drug Overdose; Drug Therapy, Combination; Emergency Medicine; Fem | 1993 |
Arterial hypertension, nifedipine, and myasthenia gravis.
Topics: Humans; Hypertension; Male; Middle Aged; Myasthenia Gravis; Nifedipine | 1993 |
[Nifedipine reduces the increase of free intracellular calcium in primary hyperparathyroidism: role of calcium channels and PTH].
Topics: Analysis of Variance; Calcium; Calcium Channel Blockers; Calcium Channels; Female; Humans; Hyperpara | 1995 |
Inhibitory effect of cilnidipine on pressor response to acute cold stress in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Cold Temperature; Dihydropyridine | 1995 |
[Long-term treatment with calcium antagonists: advantageous effects and risks].
Topics: Calcium Channel Blockers; Controlled Clinical Trials as Topic; Humans; Hypertension; Myocardial Infa | 1995 |
[Mechanism of inhibition of aldosterone secretion by a Ca2+ channel blocker in patients with essential hypertension and patients with primary aldosteronism].
Topics: Adult; Aged; Aldosterone; Calcium Channel Blockers; Depression, Chemical; Female; Humans; Hyperaldos | 1995 |
Alternatives to oral antihypertensive agents.
Topics: Administration, Sublingual; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Vasodilator | 1995 |
Endothelial function in deoxycorticosterone-NaCl hypertension: effect of calcium supplementation.
Topics: Acetylcholine; Adenosine Diphosphate; Animals; Apamin; Arginine; Blood Pressure; Calcium, Dietary; D | 1996 |
Management of moderate to severe hypertension and proteinuria by nifedipine retard and perindopril after renal transplantation.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Creatinine; Delayed-Actio | 1995 |
The use of short acting calcium channel blockers.
Topics: Calcium Channel Blockers; Humans; Hypertension; Myocardial Infarction; Nifedipine | 1996 |
Calcium blockers and risk of myocardial infarction and coronary heart disease mortality.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Hemod | 1996 |
Nifedipine study.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cause of Death; Coronary Disease; Humans; Hyperte | 1996 |
Nimodipine in patients with heart disease.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Cerebrovascular Disorders; Clinical Trials as Top | 1996 |
Nifedipine trials.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hyperte | 1996 |
Nifedipine in patients with heart disease.
Topics: Administration, Sublingual; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as To | 1996 |
Corrections to the nifedipine meta-analysis.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Coronary Disease; Dose-Response Relationship, Dru | 1996 |
[The use of the delayed-action form of korinfar in arterial hypertension, stenocardia and hypertrophic cardiomyopathy].
Topics: Adult; Aged; Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Cardiomyopathy, Hyp | 1996 |
Implementation of local guidelines for cost-effective management of hypertension. A trial of the firm system.
Topics: Antihypertensive Agents; Atenolol; Cost-Benefit Analysis; Female; Health Education; Hospitals, Veter | 1996 |
Regional vascular effects of MPC-1304, a novel dihydropyridine derivative, in conscious normotensive and spontaneously hypertensive rats.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate | 1996 |
[Calcium antagonists: safe or unsafe?].
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Meta-Analysis as Topic; My | 1996 |
Nifedipine-induced gingival enlargement around dental implants: a clinical report.
Topics: Animals; Calcium Channel Blockers; Cats; Dental Care for Chronically Ill; Dental Implants; Female; G | 1995 |
[Effect of cilnidipine on renal function in SHR and endothelin-induced renal dysfunction].
Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Endothelins; Hyp | 1996 |
Clinical outcome of a mandatory formulary switch for dihydropyridine calcium channel blocker therapy at a Veteran's Administration Medical Center.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Connecticut; Felodipine; Female; Formularies, Hospit | 1996 |
Influence of age on the relaxation induced by nifedipine in aorta from spontaneously hypertensive and Wistar Kyoto rats.
Topics: Aging; Animals; Aorta; Endothelium, Vascular; Hypertension; Male; Muscle Contraction; Muscle, Smooth | 1995 |
Blood pressure and myocardial perfusion in hypertensive patients with and without left ventricular hypertrophy.
Topics: Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Calcium Channel Blockers; Captopril; Coron | 1995 |
Receptor occupation and pharmacokinetics of MPC-1304, a new Ca2+ channel antagonist, in spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Aorta; Binding, Competitive; Calcium Channel Blockers; Cerebral Corte | 1995 |
Hemodynamic effects of oral nifedipine in preeclamptic hypertensive emergencies.
Topics: Administration, Oral; Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Emergencies; Femal | 1996 |
Revisiting calcium channel blockers--from basic facts to clinical practice.
Topics: Aged; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Humans; Hypertension; Nifedipine | 1996 |
[The clinical efficacy of Korinfar-retard in combination with Cordanum, triampur and Capoten in patients with arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Captopril; Delayed-Action Preparations; Drug Combinations; Dru | 1996 |
Inhibited neutrophil functions in patients treated with nifedipine but not with verapamil or diltiazem.
Topics: Adult; Calcium; Calcium Channel Blockers; Chemotaxis, Leukocyte; Diltiazem; Humans; Hypertension; Ne | 1996 |
Regression of increased left ventricular masses in elderly hypertensive patients on lisinopril as assessed by magnetic resonance imaging.
Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; | 1996 |
Hypertensive urgencies: how to give a low dose of short-acting nifedipine.
Topics: Administration, Sublingual; Aged; Calcium Channel Blockers; Emergencies; Humans; Hypertension; Nifed | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium | 1996 |
The influence of blood pressure on intracellular Ca2+ content in erythrocytes: effects of cadmium chloride and nifedipine.
Topics: Animals; Blood Pressure; Cadmium Chloride; Calcium; Calcium Channel Blockers; Cytosol; Erythrocytes; | 1996 |
"Drug may have caused huge number of deaths": lessons learned during an encounter with The Fifth Estate.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Canada; Conflict of Interest; Drug Industry; Huma | 1996 |
Sample sizes and withdrawals in clinical trials.
Topics: Angina Pectoris; Humans; Hypertension; Nifedipine; Patient Dropouts; Patient Selection; Publishing; | 1996 |
[Case of a hypertensive centenarian who was able to record 24-hr ambulatory blood pressure].
Topics: Aged; Aged, 80 and over; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Bloc | 1996 |
Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Dose-Response Relationship, | 1996 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hype | 1996 |
Efficacy of different antihypertensive drugs in the emergency department.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Emergency Medical Services; Enalaprilat; Femal | 1996 |
Effect of nifedipine, captopril and prazosin on secretory function of pancreatic beta-cells in hypertensive patients with type-2 (non-insulin-dependent) diabetes and in hypertensive non-diabetics.
Topics: Adult; Antihypertensive Agents; Blood Glucose; C-Peptide; Calcium Channel Blockers; Captopril; Diabe | 1996 |
Membranous nephropathy associated with oxaprozin treatment.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Back Pain; Capillaries; Complement C3; Edema; Epithe | 1996 |
Phaeochromocytoma--a rare cause of hypertension in an 11-year-old girl.
Topics: Adrenal Gland Neoplasms; Antihypertensive Agents; Calcium Channel Blockers; Catecholamines; Child; F | 1996 |
"Inappropriate" physician habits in prescribing oral nifedipine capsules in hospitalized patients.
Topics: Administration, Oral; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1996 |
Antihypertensive effects of a new transdermal delivery system for clonidine in genetic and experimental hypertensive rats.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blocker | 1996 |
1,4-Dihydropyridines versus beta-blockers for hypertension: are either safe for the heart?
Topics: Adrenergic beta-Antagonists; Adult; Aged; Calcium Channel Blockers; Coronary Disease; Dihydropyridin | 1996 |
Controversies concerning calcium antagonists.
Topics: Calcium Channel Blockers; Clinical Trials as Topic; Coronary Disease; Humans; Hypertension; Nifedipi | 1996 |
Calcium channel blocker debate: true lies?
Topics: Angina Pectoris; Calcium Channel Blockers; Humans; Hypertension; Myocardial Contraction; Myocardial | 1996 |
The STONE Study (Shanghai Trial of Hypertension in the Elderly): a meeting report.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; China; Humans; Hypertension; Middle Aged; Nifedipine | 1996 |
Effect of antihypertensive treatment and N omega-nitro-L-arginine methyl ester on cardiovascular structure in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Blood Pressure | 1996 |
Antihypertensive effect of drugs: statistical distribution of the trough-to-peak ratio.
Topics: Analysis of Variance; Antihypertensive Agents; Atenolol; Biometry; Blood Pressure; Data Interpretati | 1996 |
Relationship between nifedipine sensitivity of aortae and blood pressure of stroke-prone spontaneously hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Cerebrovascular Disorders; Hypertension; In Vitro Techniques; Male; | 1996 |
Evidence for the risk of calcium channel blockers in hypertension was selective.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Selection Bias | 1996 |
Alterations in structure of elastic laminae of rat pulmonary arteries in hypoxic hypertension.
Topics: Animals; Calcium Channel Blockers; Cardiac Output; Elasticity; Hypertension; Hypoxia; Male; Microsco | 1996 |
Autoregulation of total and zonal glomerular filtration rate in spontaneously hypertensive rats during antihypertensive therapy.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 1996 |
[Is there a risk in treatment of hypertension with nifedipine?].
Topics: Calcium Channel Blockers; Cause of Death; Humans; Hypertension; Nifedipine; Risk Factors | 1996 |
Effects of nifedipine treatment on the renin-angiotensin-aldosterone axis.
Topics: Aged; Aldosterone; Blood Pressure; Delayed-Action Preparations; Female; Humans; Hypertension; Male; | 1997 |
Influence of cisapride on the pharmacokinetics and antihypertensive effect of sustained-release nifedipine.
Topics: Aged; Calcium Channel Blockers; Cisapride; Delayed-Action Preparations; Drug Interactions; Female; G | 1996 |
The antihypertensive effect of orally administered nifedipine-loaded nanoparticles in spontaneously hypertensive rats.
Topics: Acrylic Resins; Animals; Antihypertensive Agents; Area Under Curve; Blood Pressure; Calcium Channel | 1997 |
The effect of nifedipine on serum endothelin-1 levels in essential hypertension.
Topics: Administration, Sublingual; Adult; Blood Pressure; Calcium Channel Blockers; Endothelin-1; Female; H | 1997 |
Nifedipine and other calcium channel blockers.
Topics: Calcium Channel Blockers; Cause of Death; Humans; Hypertension; Nifedipine; Risk; Survival Analysis; | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Antihypertensive Agents; Drug Utilization; Emergencies; Humans; Hypertension; Nifedipine; Practice P | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Antihypertensive Agents; Drug Utilization; Emergencies; Humans; Hypertension; Nifedipine; Practice P | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Administration, Sublingual; Antihypertensive Agents; Drug Utilization; Emergencies; Humans; Hyperten | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Utilization; Emergencies; Humans; Hy | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Antihypertensive Agents; Drug Utilization; Emergencies; Humans; Hypertension; Nifedipine | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Anesthesia, Conduction; Antihypertensive Agents; Cataract Extraction; Emergencies; Humans; Hypertens | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Administration, Sublingual; Antihypertensive Agents; Capsules; Emergencies; Humans; Hypertension; Ni | 1997 |
Nifedipine for hypertensive emergencies.
Topics: Antihypertensive Agents; Emergencies; Humans; Hypertension; Nifedipine; Practice Patterns, Physician | 1997 |
Effect of barnidipine on blood flow to major organs and renal function in anaesthetized dogs and spontaneously hypertensive rats.
Topics: Anesthesia; Animals; Antihypertensive Agents; Calcium Channel Blockers; Diuresis; Dogs; Female; Hype | 1995 |
Hypotensive effects of a new transdermal delivery system for clonidine (M-5041T) in spontaneously and renal hypertensive rats.
Topics: Administration, Cutaneous; Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; C | 1995 |
Cardiac lipoprotein lipase in the spontaneously hypertensive rat.
Topics: Adenosine; Animals; Calcium Channel Blockers; Heparin; Hypertension; Intracellular Fluid; Lipoprotei | 1997 |
Hypotensive effects of YM430, a 1,4-dihydropyridine derivative, in spontaneously hypertensive rats and renal hypertensive dogs.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Calcium Channel | 1997 |
Pharmacokinetic and pharmacodynamic differences between nifedipine capsule and GITS formulations in hypertensive patients.
Topics: Biological Availability; Blood Pressure; Calcium Channel Blockers; Capsules; Delayed-Action Preparat | 1997 |
Defective excitation-contraction coupling in experimental cardiac hypertrophy and heart failure.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Chan | 1997 |
Effect of sublingual nifedipine on left ventricular diastolic dysfunction in hypertensives: echo-Doppler study at rest and during handgrip.
Topics: Administration, Sublingual; Adult; Calcium Channel Blockers; Diastole; Echocardiography, Doppler; Ha | 1996 |
Sympathetic modulation of the effect of nifedipine on myocardial contraction and Ca current in the rat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Calcium Channel Blockers; | 1997 |
The effect of nifedipine and methyldopa on maternal cerebral circulation.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Cerebral Arteries; Cerebrovascular Cir | 1997 |
Intracellular free magnesium concentrations in skeletal muscle in chronic uraemia.
Topics: Adult; Aged; Antihypertensive Agents; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Chron | 1997 |
Hypertension in children.
Topics: Adult; Biological Availability; Capsules; Child; Humans; Hypertension; Nifedipine | 1997 |
Metabolic effects of long-term treatments with nifedipine-retard and captopril in young hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Captopril; Female; Humans; | 1997 |
24-hour blood pressure monitoring to evaluate the effects of nifedipine in pre-eclampsia and in chronic hypertension in pregnancy.
Topics: Adult; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chronic Dise | 1997 |
Alterations in alpha subunit expression of cardiac Na+,K+-ATPase in spontaneously hypertensive rats: effect of antihypertensive therapy.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Hy | 1997 |
Effects of long-term antihypertensive therapy on physical fitness of men with mild hypertension.
Topics: Acebutolol; Adrenergic beta-Antagonists; Adult; Blood Pressure; Calcium Channel Blockers; Drug Thera | 1997 |
The calcium channel blocker controversy in 1997.
Topics: Calcium Channel Blockers; Cardiac Output, Low; Case-Control Studies; Clinical Trials as Topic; Human | 1997 |
Antihypertensive effect of some oxazolo[3,2-a]pyridines, thiazolo[3,2-a]pyridines and pyrido[2,1-b]oxazines in conscious spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; | 1997 |
The effects of cyclopiazonic acid on intracellular Ca2+ in aortic smooth muscle cells from DOCA-hypertensive rats.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Desoxycorti | 1997 |
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats.
Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biphenyl Compounds; Captopril; Cells, Cultur | 1997 |
Cardiac heparin-releasable lipoprotein lipase activity in fructose-hypertensive rats: effect of coronary vasodilation.
Topics: Adenosine; Animals; Blood Glucose; Blood Pressure; Coronary Vessels; Fructose; Heparin; Hypertension | 1997 |
Protective effects of CD-832 on organ damage in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Cerebrovascular Disorders; Diltiazem | 1997 |
Effects of m-nifedipine on dihydropyridine binding sites in hypertrophied left ventricular cell membranes from deoxycorticosterone acetate-salt hypertensive rats.
Topics: Animals; Binding Sites; Calcium; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; H | 1996 |
Insulin responses to oral glucose during 4-year treatment with nifedipine retard in hypertensive patients with and without NIDDM.
Topics: Administration, Oral; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Glucose; Glucose Toleranc | 1997 |
A pharmacogenetic approach to blood pressure in Lyon hypertensive rats. A chromosome 2 locus influences the response to a calcium antagonist.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Chrom | 1997 |
A cautionary tale.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Calcium Channel Blockers; Ch | 1997 |
Role of endothelium in the endothelin-1-mediated potentiation of the norepinephrine response in the aorta of hypertensive rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta, Thoracic; Bridge | 1997 |
Calcium signaling mechanisms in renal vascular responses to vasopressin in genetic hypertension.
Topics: Animals; Arginine Vasopressin; Calcium; Dose-Response Relationship, Drug; Drug Combinations; Gallic | 1997 |
Nifedipine GITS replacing nifedipine SR: ambulatory blood pressure assessment of efficacy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, | 1997 |
Sublingual nifedipine in human pregnancy.
Topics: Administration, Sublingual; Apgar Score; Birth Weight; Calcium Channel Blockers; Female; Humans; Hyp | 1997 |
[Slow release nifedipine in treatment of hypertension. 24-hour effect on blood pressure and heart rate--treatment follow-up of 391 patients].
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Delayed-Ac | 1997 |
[Introducing mibefradil--a new T-calcium channel blocker].
Topics: Antihypertensive Agents; Benzimidazoles; Calcium Channel Blockers; Diltiazem; Humans; Hypertension; | 1997 |
Short-acting nifedipine.
Topics: Adolescent; Calcium Channel Blockers; Female; Humans; Hypertension; Infant, Newborn; Male; Nifedipin | 1997 |
Tachycardia, orthostatic hypotension and profound weakness due to concomitant use of fluoxetine and nifedipine.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Drug Interactions; Drug | 1997 |
Evaluation of the antihypertensive effect of barnidipine, a dihydropyridine calcium entry blocker, as determined by the ambulatory blood pressure level averaged for 24 h, daytime, and nighttime. Barnidipine Study Group.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium | 1997 |
Antihypertensive agents that limit ventricular hypertrophy inhibit cardiac expression of insulin-like growth factor-I.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Enalapril; Heart; Hydralazine; Hypertension; Hyper | 1997 |
[Effect of transient cerebral ischemia on the synthesis of prostacyclin in dogs with arterial hypertension].
Topics: Animals; Calcium Channel Blockers; Coronary Thrombosis; Dogs; Epoprostenol; Hypertension; Ischemic A | 1997 |
Efficient inhibition of the development of cardiac remodeling by a long-acting calcium antagonist amlodipine.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiomegaly; Collagen; Hear | 1998 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Australia; Calcium Channel Blockers; Contraindications; Drug Labeling; Female; Humans | 1998 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Administration, Oral; Administration, Sublingual; Blood Pressure; Calcium Channel Blo | 1998 |
Withdrawal of nifedipine capsules: jeopardising the treatment of acute severe hypertension in pregnancy?
Topics: Acute Disease; Administration, Oral; Australia; Blood Pressure; Calcium Channel Blockers; Capsules; | 1998 |
Renal effects of the calcium channel blocker aranidipine and its active metabolite in anesthetized dogs and conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dihydropyridine | 1998 |
[New nifedipine preparation makes single daily dose possible].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hyperte | 1997 |
Pregnancy-induced hypertension, antihypertensive drugs and the development of fetal behavioural states.
Topics: Antihypertensive Agents; Cohort Studies; Embryo, Mammalian; Embryonic and Fetal Development; Female; | 1998 |
Ultrastructural changes during myocardial hypertrophy and its regression: long-term effects of nifedipine in adult spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Capillaries; Cell Size; Heart Ventricles; Hypertension; Hypertrophy, Left V | 1997 |
Enhanced efficacy of nilvadipine in hypertensives whose raised ambulatory blood pressure is sustained during sleep.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Female; Hum | 1998 |
Prevalence of coronary calcification in relation to age, gender and risk factor profile in the insight population.
Topics: Calcinosis; Calcium Channel Blockers; Coronary Angiography; Coronary Disease; Diabetes Complications | 1997 |
The clinical effects of nifedipine on periodontal status.
Topics: Adult; Age Factors; Aged; Analysis of Variance; Angina Pectoris; Calcium Channel Blockers; Dental Pl | 1998 |
The effects of lisinopril and nifedipine on parotid function: two case reports.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Female; | 1992 |
Different effects of calcium antagonists on fluid filtration of large arteries and albumin permeability in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Capillary Permeabilit | 1998 |
[Diagnostic and therapeutic procedures by doctors for patients in a hypertensive crisis. An inquiry in 56 internal medicine clinics].
Topics: Acute Disease; Administration, Sublingual; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists | 1998 |
Once-daily nifedipine sustained release (nifelan) on forearm vascular resistance and regression of left ventricular hypertrophy in patients with mild to moderate essential hypertension.
Topics: Adult; Aged; Calcium Channel Blockers; Female; Forearm; Hemodynamics; Humans; Hypertension; Hypertro | 1998 |
Replacing short-acting nifedipine with alternative medications at a large health maintenance organization.
Topics: Aged; Calcium Channel Blockers; Cohort Studies; Delayed-Action Preparations; Drug Utilization; Felod | 1998 |
[Premedication with different groups of hypotensive drugs in preparation of patients with concomitant arterial hypertension to planned surgical treatment].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Clonidine; Female; Humans; Hypertension; H | 1998 |
A moratorium should be placed on the use of short-acting nifedipine for hypertensive crises.
Topics: Calcium Channel Blockers; Child; Female; Humans; Hypertension; Hypotension; Nifedipine | 1998 |
Effects of 3-month nifedipine treatment on endocrine-metabolic parameters in patients with abdominal obesity and mild hypertension.
Topics: Adult; Blood Glucose; Body Constitution; Body Mass Index; Calcium Channel Blockers; Dehydroepiandros | 1998 |
[Levels of malonyl dialdehyde and vitamin A in blood serum after administration of therapeutic doses of nifedipine].
Topics: Adult; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Malondialdehyde; Middle Aged; N | 1998 |
Efficacy and tolerability of once-daily barnidipine in the clinical management of patients with mild to moderate essential hypertension.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; M | 1998 |
Diversity and intensity of adverse events in the treatment of hypertension with barnidipine.
Topics: Aged; Calcium Channel Blockers; Humans; Hypertension; Nifedipine; Treatment Outcome | 1998 |
Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR.
Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Ag | 1998 |
Effect of the vasodilatory beta-blocker, nipradilol, and Ca-antagonist, barnidipine, on insulin sensitivity in patients with essential hypertension.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Calcium Channel Blockers; Female; Glucose Clamp Techniq | 1998 |
I take Adalat (or nifedipine, also sold as Procardia) and captopril tablets daily for my high blood pressure. My physician told me not to take aspirin because of the possibility of drug interactions. From what I have read about aspirin, I hate to miss out
Topics: Aspirin; Captopril; Drug Interactions; Humans; Hypertension; Nifedipine | 1998 |
Early management of acute stroke in emergency departments: preliminary findings. Florida Medical Quality Assurance, Inc.
Topics: Acute Disease; Blood Pressure; Cerebrovascular Disorders; Cross-Sectional Studies; Electrocardiograp | 1998 |
Nifedipine and extracellular water in dialysis arterial hypertension.
Topics: Adult; Aged; Body Fluid Compartments; Calcium Channel Blockers; Echocardiography; Electric Impedance | 1998 |
Effects of treatment with nilvadipine on cerebral ischemia in rats.
Topics: Animals; Antihypertensive Agents; Brain; Calcium Channel Blockers; Cerebral Infarction; Hypertension | 1998 |
[The changes of intraerythrocyte calcium metabolism and their responses to nifedipine in patients with essential hypertension].
Topics: Adenosine Triphosphatases; Angiotensin II; Biological Transport, Active; Calcium; Calcium Channel Bl | 1997 |
Quality of life and calcium channel blockade with nifedipine GITS versus amlodipine in hypertensive patients in Spain. Gastrointestinal Therapeutic System.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind | 1998 |
Development of tablets for controlled joint release of nifedipine and atenolol.
Topics: Atenolol; Calcium Channel Blockers; Chemical Phenomena; Chemistry, Physical; Delayed-Action Preparat | 1998 |
Comparison of 24-hour ambulatory blood pressure data in hypertensive patients switched from nifedipine-GITS to nifedipine-CC.
Topics: Adult; Aged; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dosage Forms; Female; | 1999 |
Antihypertensive properties of KRN4884, a novel long-lasting potassium channel opener.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Cromaka | 1999 |
[A 73-year-old patient with hypertensive crisis. Was the use of calcium antagonist nifedipine justified?].
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Electrocardiogra | 1999 |
Effects of two calcium channel blockers on messenger RNA expression of endothelin-1 and nitric oxide synthase in cardiovascular tissue of hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Blotting, Southern; Brain; Calcium Channel Blockers; Cardiovascular | 1999 |
P&T Committee review of nifedipine GITS: new modality for angina and hypertension.
Topics: Angina Pectoris; Drug Evaluation; Formularies, Hospital as Topic; Hypertension; Nifedipine; Pharmacy | 1990 |
[Copper, zinc and vitamin C concentrations in polymorphonuclear granulocytes after administration of therapeutic doses of nifedipine in patients with primary hypertension].
Topics: Adult; Ascorbic Acid; Calcium Channel Blockers; Copper; Humans; Hypertension; Male; Middle Aged; Neu | 1998 |
Nifedipine effectively lowers salt-induced high blood pressure in diabetic rats.
Topics: Animals; Blood Pressure; Diabetic Angiopathies; Hypertension; Male; Nifedipine; Norepinephrine; Rats | 1999 |
Clinical presentation and management of patients with uncontrolled, severe hypertension: results from a public teaching hospital.
Topics: Acute Disease; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clonidine; Cross-S | 1999 |
Paracrine role of adventitial superoxide anion in mediating spontaneous tone of the isolated rat aorta in angiotensin II-induced hypertension.
Topics: Acridines; Angiotensin II; Animals; Anions; Aorta, Thoracic; Calcium; Data Interpretation, Statistic | 1999 |
Efficacy of sublingual verapamil in patients with severe essential hypertension: comparison with sublingual nifedipine.
Topics: Administration, Sublingual; Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Headache; | 1999 |
The effects of short-term nifedipine treatment on responsiveness of aortic rings of cadmium-hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Blood Pressure; Cadmium Chloride; Calcium C | 1999 |
[Hypertensive manifestation of an acute intestinal intussusception].
Topics: Acute Disease; Barium Sulfate; Calcium Channel Blockers; Enema; Humans; Hypertension; Infant; Intuss | 1999 |
Effect of Ca2+ channel blockers on arterial hypertension and heart ischaemic lesions induced by chronic blockade of nitric oxide in the rat.
Topics: Animals; Blood Pressure; Blood Pressure Determination; Body Weight; Calcium Channel Blockers; Diltia | 1999 |
Mortality in the Jerusalem 70-year-olds longitudinal study: does nifedipine have a role?
Topics: Aged; Coronary Disease; Creatinine; Diuretics; Female; Heart Failure; Humans; Hypertension; Israel; | 1999 |
Hypertensive encephalopathy and nephrotic syndrome: a possible link?
Topics: Anti-Inflammatory Agents; Antihypertensive Agents; Azathioprine; Brain Diseases; Calcium Channel Blo | 1999 |
Platelet hyperactivity in hypertensive older patients is controlled by lowering blood pressure.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Blood Pre | 1999 |
Adverse reactions to short-acting nifedipine in hypertensive crises.
Topics: Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 1999 |
[Effects of benidipine hydrochloride (Coniel) on blood pressure, heart rate and plasma norepinephrine concentration in spontaneously hypertensive rats].
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Heart Rate; Hyperte | 1999 |
Chronic hypertension with subsequent congestive heart failure in a western lowland gorilla (Gorilla gorilla gorilla).
Topics: Animals; Animals, Zoo; Antihypertensive Agents; Ape Diseases; Blood Pressure Determination; Chronic | 1999 |
Age-related difference in cardiac adaptation to chronic hypertension in rats, with and without nifedipine treatment.
Topics: Adaptation, Physiological; Aging; Animals; Antihypertensive Agents; Hypertension; Nifedipine; Rats; | 1999 |
Effects of nilvadipine on cytokine-levels and soluble factors in collagen disease complicated with essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; CD4-CD8 Ratio; Collagen Diseases; Cytokines; | 1999 |
Lesion topography in two cases of nifedipine-related pemphigus.
Topics: Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Israel; Italy; Jews; Middle Aged; Nife | 1999 |
Treatment with a Ca(2+) channel blocker, barnidipine, reduces platelet-derived growth factor B-chain mRNA in glomeruli of spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Gene Expression; Heart Rate; Hypertension; Kidney | 1999 |
The pharmacological effects of an aqueous extract from Acacia nilotica seeds.
Topics: Acacia; Acetylcholine; Animals; Atropine; Blood Pressure; Cats; Dose-Response Relationship, Drug; Gu | 1999 |
[New central agents in the treatment of arterial hypertension].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Adult; Antihyp | 1999 |
Reversible anterior ischaemic optic neuropathy in accelerated hypertension.
Topics: Administration, Sublingual; Humans; Hypertension; Nifedipine; Optic Neuropathy, Ischemic; Vasodilato | 1999 |
Pranidipine enhances the action of nitric oxide released from endothelial cells.
Topics: Amlodipine; Animals; Aorta, Thoracic; Calcium Channel Blockers; Cells, Cultured; Coculture Technique | 2000 |
Sympathoinhibition by central and peripheral infusion of nifedipine in spontaneously hypertensive rats.
Topics: Adrenal Glands; Animals; Blood Pressure; Brain Stem; Calcium Channel Blockers; Cerebral Cortex; Cere | 2000 |
Electromechanical alterations in the cerebrovasculature of stroke-prone rats.
Topics: Animals; Calcium; Calcium Channel Blockers; Cerebral Arteries; Electrophysiology; Genetic Predisposi | 2000 |
Cutting it close. It's the right dose and the right drug--how can it be too much?
Topics: Aged; Calcium Channel Blockers; Delayed-Action Preparations; Humans; Hypertension; Male; Medication | 2000 |
Arterial responses in vitro and plasma digoxin immunoreactivity after losartan and enalapril treatments in experimental hypertension.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensiv | 2000 |
Is there any difference between intermediate-acting and long-acting calcium antagonists in diurnal blood pressure and autonomic nervous activity in hypertensive coronary artery disease patients?
Topics: Autonomic Nervous System; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blo | 2000 |
Noninvasive, continuous evaluation of peripheral vascular resistance in humans.
Topics: Blood Pressure; Blood Pressure Determination; Electrocardiography; Female; Heart Rate; Humans; Hyper | 2000 |
Nifedipine in pregnancy.
Topics: Drug Interactions; Female; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car | 2000 |
Haemodynamic response following a 10% topload infusion of HemolinkTM in conscious, anaesthetized and treated spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Blood Substitutes; Blood Transfusion; Hemoglobins; Humans; Hypertension; In | 2000 |
Pemphigoid nodularis associated with nifedipine.
Topics: Aged; Humans; Hypertension; Male; Nifedipine; Pemphigoid, Bullous; Vasodilator Agents | 2000 |
[Sublingual captopril: indications and advantages?].
Topics: Administration, Oral; Administration, Sublingual; Adrenergic alpha-Antagonists; Angiotensin-Converti | 2000 |
Altered beta-adrenoceptor-mediated responses in the gastric smooth muscle of hypertensive rats.
Topics: Adrenergic beta-Agonists; Animals; Calcium; Calcium Channel Blockers; Colforsin; Electrophysiology; | 2000 |
The beneficial effects of calcium channel blockers on long-term kidney transplant survival are independent of blood-pressure reduction.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Creatinine; Follow-Up Studies; Gr | 2000 |
Nilvadipine protects low-density lipoprotein cholesterol from in vivo oxidation in hypertensive patients with risk factors for atherosclerosis.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Arteriosclerosis; Case-Control Studies; Cho | 2000 |
Nitric oxide synthase induction by ouabain in vascular smooth muscle cells from normotensive and hypertensive rats.
Topics: Animals; Blotting, Western; Calcimycin; Calcium; Calcium Channel Blockers; Cells, Cultured; Enzyme I | 2000 |
Nifedipine induces apoptosis in cultured vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Calcium; Calcium Channel Blockers; Cells, Cultured; DNA Fragmentation; Hypertens | 2000 |
Retrospective evaluation of the conversion of amlodipine to alternative calcium channel blockers.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Diltiazem; Felodipine; Female; Humans; Hyperte | 2000 |
Possible involvement of endothelin-1 in cardioprotective effects of benidipine.
Topics: Animals; Animals, Newborn; Calcium Channel Blockers; Cardiomegaly; Cells, Cultured; Dihydropyridines | 2000 |
Stroke precipitated by moderate blood pressure reduction.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Emergency Treatment; Felodipine; Female; Humans; Hyp | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Aged; Anticholesteremic Agents; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Di | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Aged; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Drug Therapy, Combination; Enalap | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Anticholesteremic Agents; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents | 2000 |
INSIGHT and NORDIL. International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment. Nordic Diltiazem Study.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; C | 2000 |
Left ventricular midwall function improves with antihypertensive therapy and regression of left ventricular hypertrophy in patients with asymptomatic hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Echocardiogr | 2001 |
Increased dilator response to heptanol and octanol in aorta from DOCA-salt-hypertensive rats.
Topics: Animals; Aorta; Desoxycorticosterone; Dose-Response Relationship, Drug; Heptanol; Hypertension; In V | 2001 |
Barnidipine: a step towards safer blood pressure control?
Topics: Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Nifedipine | 2000 |
Approach to the patient with hypertension, unexplained hypokalemia, and metabolic alkalosis.
Topics: Adenoma; Adrenalectomy; Aldosterone; Alkalosis; Antihypertensive Agents; Diagnosis, Differential; Hu | 2001 |
Occurrence and distribution of atrial natriuretic peptide-containing cells in the left ventricle of hypertensive rats. Effect of antihypertensive treatment.
Topics: Animals; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Blotting, Northern; Cap | 2001 |
A comparative study of morphological changes in spontaneously hypertensive rats and normotensive Wistar Kyoto rats treated with an angiotensin-converting enzyme inhibitor or a calcium-channel blocker.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Body Weight; Cal | 2001 |
Restoration of nitric oxide availability after calcium antagonist treatment in essential hypertension.
Topics: Acetylcholine; Antioxidants; Ascorbic Acid; Blood Pressure; Calcium Channel Blockers; Endothelium, V | 2001 |
Antihypertensive effects of Dorstenia psilurus extract in fructose-fed hyperinsulinemic, hypertensive rats.
Topics: Africa; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Cholesterol; Creatinine; Di | 2001 |
Calcium buffering of resting, voltage-dependent Ca2+ influx by sarcoplasmic reticulum in femoral arteries from spontaneously hypertensive rats at prehypertensive stage.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
[Antihypertensive effect of Herniaria glabra saponins in the spontaneously hypertensive rat].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Female; Heart Rate; Hypertension; Male; Nifedipine | 2001 |
Resetting baroreceptors to a lower arterial pressure level by enalapril avoids baroreflex mediated activation of sympathetic nervous system by nifedipine.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium | 2001 |
Factor analysis, including antihypertensive medication, of the outcome of pregnancy in pregnancy-associated hypertension.
Topics: Antihypertensive Agents; Apgar Score; Cesarean Section; Comorbidity; Disease Susceptibility; Female; | 2001 |
The use of short-acting nifedipine in children with hypertension: another example of the need for comprehensive drug testing in children.
Topics: Age Factors; Antihypertensive Agents; Child; Clinical Trials as Topic; Humans; Hypertension; Nicardi | 2001 |
The use of short-acting nifedipine in pediatric patients with hypertension.
Topics: Adolescent; Antihypertensive Agents; Blood Pressure; Body Weight; Case-Control Studies; Child; Child | 2001 |
Norepinephrine-induced calcium signaling pathways in afferent arterioles of genetically hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Arterioles; Calcium; Calcium Channel Blockers; Calcium Channels; | 2001 |
Efficacy and safety of a therapeutic interchange from high-dose calcium channel blockers to a fixed-dose combination of amlodipine/benazepril in patients with moderate-to-severe hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Blood Pressure; Calcium Channel Bloc | 2001 |
In vivo visualization of characteristics of renal microcirculation in hypertensive and diabetic rats.
Topics: Animals; Arterioles; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Hemo | 2001 |
Semipersonalized psychological evaluation of quality of life in hypertensive patients during a trial with two calcium antagonists: a multicenter Latin-American Study (LASTLHY).
Topics: Activities of Daily Living; Administration, Oral; Adult; Aged; Antihypertensive Agents; Calcium Chan | 2001 |
Pharmacist-managed hypertension therapy conversion.
Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Calcium Channel Blockers; Drug Costs; Fem | 2001 |
The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives.
Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Blood P | 2001 |
Dihydropyridine calcium channel blockers and peripheral side effects.
Topics: Calcium Channel Blockers; Dihydropyridines; Edema; Erythema; Exanthema; Humans; Hyperpigmentation; H | 2001 |
Ca2+ influx mediates enhanced alpha2-adrenergic contraction in aortas from rats treated with NOS inhibitor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2001 |
Use of oral antihypertensive medication preceding blood pressure elevation in hospitalized patients.
Topics: Administration, Oral; Antihypertensive Agents; Captopril; Female; Hospitalization; Humans; Hypertens | 2001 |
Chronic hypertension impairs flow-induced vasodilation and augments the myogenic response in fetal lung.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Chronic Disease; Ductus Arteriosus; Enzyme Inhi | 2002 |
Adverse neurologic events associated with rebound hypertension after using short-acting nifedipine in childhood hypertension.
Topics: Child; Female; Humans; Hypertension; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Male; | 2001 |
Evaluation of the safety of short-acting nifedipine in children with hypertension.
Topics: Adolescent; Blood Pressure; Calcium Channel Blockers; Child; Child, Preschool; Dose-Response Relatio | 2002 |
Carbamazepine decreases antihypertensive effect of nilvadipine.
Topics: Antihypertensive Agents; Antimanic Agents; Carbamazepine; Drug Interactions; Humans; Hypertension; M | 2002 |
Endothelial factors and microvascular hypertensive disease.
Topics: Acetylcholine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; | 2001 |
[Misleading advertisement of Adalat Oros].
Topics: Advertising; Calcium Channel Blockers; Data Interpretation, Statistical; Diuretics; Humans; Hyperten | 2002 |
[Misleading advertisement of Adalat Oros].
Topics: Advertising; Calcium Channel Blockers; Data Interpretation, Statistical; Deception; Diuretics; Human | 2002 |
Test and teach. Surgically correctable hypertension. Conn's syndrome and spironolactone bodies.
Topics: Adenoma; Adrenal Cortex Neoplasms; Adrenalectomy; Aldosterone; Humans; Hyperaldosteronism; Hypertens | 2001 |
Effect of nitric oxide synthase inhibitor N(omega) nitro-L-arginine methyl ester on relaxant responses to calcium channel antagonists in isolated aortic rings from Dahl normotensive and hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diltiazem; Enzyme Inhibitors; Female; Hypertensi | 2002 |
[Characteristics of sympathetic adrenal responses in marginal arterial hypertension].
Topics: Adult; Blood Pressure; Electrocardiography; Epinephrine; Heart Rate; Humans; Hypertension; Military | 2002 |
Novel mechanisms of the antiproliferative effects of amlodipine in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cell Division; Cells, Cultured; Growth Substances; Hy | 2002 |
Continuous blockade of L-type Ca2+ channels suppresses activation of calcineurin and development of cardiac hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Calcineurin Inhibitors; Calcium Channel Blockers | 2002 |
Blood pressure response in 24 hours in patients with high blood pressure treated with two nifedipine formulations once a day.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Double-Blind Method; H | 2002 |
Did nurses fail to 'give Procardia' as ordered? Case on point: Piro v. Chandler, 2000 WL 1634167 So.2d--LA.
Topics: Humans; Hypertension; Male; Malpractice; New Jersey; Nifedipine; Nursing Staff, Hospital; Stroke; Va | 2000 |
Influence of non-steroidal anti-inflammatory drugs on the blood-pressure-reducing effects of enalapril and nifedipine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Drug Interactions; | 1996 |
Aortic smooth muscle cell phenotypic modulation and fibrillar collagen deposition in angiotensin II-dependent hypertension.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Geneticall | 2002 |
Nifedipine in the treatment of hypertension in children.
Topics: Child; Humans; Hypertension; Nifedipine; Vasodilator Agents | 2002 |
Effects of antihypertensive therapy on cardiac sodium/hydrogen ion exchanger activity and hypertrophy in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Disease Mo | 2002 |
[Individual therapy of coronary disease].
Topics: Coronary Disease; Edema; Humans; Hypertension; Leg; Myocardial Infarction; Nifedipine; Pyridines | 1979 |
[Influence of nifedipine on the response to exercise in hypertensive patients].
Topics: Adult; Exercise Test; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1978 |
[Nifedipine in the treatment of hypertensive crises in acute myocardial infarct].
Topics: Humans; Hypertension; Myocardial Infarction; Nifedipine; Pyridines | 1978 |
[Physiopathological aspects of calcium metabolism at the myocardial level. Clinical experience with nifedipine].
Topics: Calcium; Coronary Disease; Female; Humans; Hypertension; Male; Myocardium; Nifedipine; Pyridines | 1978 |
Effects of nifedipine on blood pressure, regional hemodynamics, plasma renin activity and plasma catecholamines in patients with arterial hypertension.
Topics: Blood Pressure; Epinephrine; Hemodynamics; Humans; Hypertension; Nifedipine; Norepinephrine; Pyridin | 1979 |
Acute and chronic effects of nifedipine on plasma renin activity and plasma adrenaline and noradrenaline in controls and hypertensive patients.
Topics: Adult; Blood Pressure; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nif | 1979 |
[Changes in plasma renin activity induced by acute administration of nifedipine in hypertensive patients (author's transl)].
Topics: Humans; Hypertension; Middle Aged; Nifedipine; Pyridines; Renin | 1979 |
[Hemodynamic, humoral and renal effects of the acute administration of nifedipine in hypertensive patients].
Topics: Adult; Aged; Aldosterone; Blood Pressure; Catecholamines; Creatinine; Electrolytes; Female; Heart Ra | 1979 |
Clinical use of a calcium antagonistic agent (nifedipine) in acute pulmonary edema.
Topics: Adult; Aged; Blood Pressure; Calcium; Cardiomyopathies; Female; Humans; Hypertension; Male; Middle A | 1979 |
Effect of nifedipine on plasma renin, aldosterone and catecholamines in arterial hypertension.
Topics: Adult; Aged; Aldosterone; Catecholamines; Evaluation Studies as Topic; Female; Hemodynamics; Humans; | 1979 |
Tension development and Ca2+ uptake of isolated aorta from spontaneously hypertensive rats.
Topics: Animals; Aorta; Calcium; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Ra | 1979 |
[Effect of nifedipine in long-term administration on myocardial contraction and cardiac output in hypertensive coronary disease patients].
Topics: Adult; Aged; Cardiac Output; Coronary Disease; Humans; Hypertension; Middle Aged; Myocardial Contrac | 1978 |
[Calcium antagonists: hemodynamic effects in hypertensive patients].
Topics: Calcium; Hemodynamics; Humans; Hypertension; Nifedipine; Pyridines; Verapamil | 1979 |
[Treatment of hypertensive crises with calcium antagonists].
Topics: Antihypertensive Agents; Calcium; Drug Therapy, Combination; Humans; Hypertension; Hypertension, Ren | 1978 |
[Nifedipine in the treatment of hypertensive crises].
Topics: Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1978 |
[Effects of nifedipine on arterial hypertension: study of 26 cases].
Topics: Adult; Aged; Humans; Hypertension; Hypertension, Renal; Hypertension, Renovascular; Male; Middle Age | 1978 |
[Calcium antagonists: an echocardiographic evaluation of the morphofunctional changes in the left ventricle].
Topics: Calcium; Echocardiography; Female; Heart; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; | 1979 |
[Analogy of response to acute and chronic nifedipine therapy in hypertensive and non-hypertensive patients].
Topics: Adult; Angina Pectoris; Coronary Disease; Electrocardiography; Female; Heart; Hemodynamics; Humans; | 1979 |
Antihypertensive effect of cardiovascular Ca2+-antagonist in hypertensive patients in the absence and presence of beta-adrenergic blockade.
Topics: Adult; Blood Pressure; Calcium; Cardiac Output; Female; Furosemide; Heart Rate; Humans; Hypertension | 1978 |
Effects of extracellular calcium on potassium and noradrenaline induced contractions in the aorta of spontaneously hypertensive rats--increased sensitivity to nifedipine.
Topics: Animals; Aorta; Arteries; Calcium; Extracellular Space; Hypertension; Male; Muscle Contraction; Musc | 1978 |
A study on the effects of nifedipine in hypertensive crises and severe hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium; Cardiac Output; Female; Humans; Hypertension; Hypertension, Re | 1978 |
Acute and chronic effects of nifedipine in arterial hypertension.
Topics: Adult; Blood Pressure; Body Weight; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyr | 1978 |
[Influence of calcium antagonist, nifedipine, on arterial pressure. Preliminary considerations].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Blood Vessels; Female; Heart Rate; Humans; Hyp | 1978 |
[Calcium antagonists in the therapy of arterial hypertension].
Topics: Blood Pressure; Calcium; Heart; Humans; Hypertension; Nifedipine; Pyridines; Vascular Resistance | 1978 |
[Effect of Nifedipine (Adalat) on haemodynamic changes in patients with hypertension (author's transl)].
Topics: Blood Pressure; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Pyridines | 1977 |
Nifedipine, a new antihypertensive with rapid action.
Topics: Administration, Oral; Antihypertensive Agents; Blood Pressure; Cardiac Output; Female; Heart Rate; H | 1977 |
Hypotensive action and increased plasma renin activity by Ca2+ antagonist (Nifedipine) in hypertensive patients.
Topics: Adult; Calcium; Heart Rate; Humans; Hypertension; Middle Aged; Nifedipine; Pyridines; Renin | 1976 |
[Cardiac interactions between ketanserin and the calcium antagonist nifedipine].
Topics: Aged; Arrhythmias, Cardiac; Blood Pressure; Cardiac Complexes, Premature; Drug Interactions; Drug Th | 1992 |
Antihypertensive effects of MPC-1304, a novel calcium antagonist, in experimental hypertensive rats and dogs.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Co | 1992 |
Advances in antihypertensive treatment--profile of a new dihydropyridine. Proceedings of the 1st Nilvadipine Symposium. Munich, May 16, 1992.
Topics: Antihypertensive Agents; Humans; Hypertension; Nifedipine | 1992 |
Nilvadipine in hypertension with renal dysfunction.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Blood Pressure; Creatinine; Female; Heart Rate; H | 1992 |
Treatment of hypertension induces a fall in platelet basal cytoplasmic calcium concentration without influencing platelet aggregation.
Topics: Adult; Aged; Basal Metabolism; Blood Platelets; Blood Pressure; Calcium; Cytoplasm; Drug Therapy, Co | 1992 |
Effect of slow release nifedipine tablets in patients with essential hypertension.
Topics: Adult; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Female; Humans; Hypertension; | 1992 |
The reactivity of peripheral vessels of normo- and hypertensives.
Topics: Adenosine Triphosphatases; Adult; Blood Pressure; Blood Proteins; Cardenolides; Digoxin; Erythrocyte | 1992 |
A sustained occupancy in vivo of cardiovascular calcium antagonist receptors by mepirodipine and its relation to pharmacodynamic effect in spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Dihydropy | 1992 |
Effects of endothelin upon blood pressure in normotensive rabbits and in perinephritis hypertension.
Topics: Animals; Arginine; Blood Pressure; Calcium; Calcium Channel Blockers; Endothelins; Hypertension; Ind | 1992 |
Effect of dietary sodium intake on intracellular calcium in lymphocytes of salt-sensitive hypertensive patients.
Topics: Adult; Blood Pressure; Calcium; Calcium Channels; Cell Separation; Cytosol; Delayed-Action Preparati | 1992 |
[Changes of subtypes of alpha 1-adrenoceptor in blood vessels of spontaneously hypertensive rats].
Topics: Animals; Blood Vessels; Hypertension; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, | 1992 |
Changes in cardiovascular mass, left ventricular pumping ability and aortic distensibility after calcium antagonists in Wistar-Kyoto and spontaneously hypertensive rats.
Topics: Animals; Aorta; Compliance; Heart; Heart Ventricles; Hemodynamics; Hypertension; Male; Nifedipine; N | 1992 |
Case report: nifedipine-rifampicin interaction attenuates the effect on blood pressure in a patient with essential hypertension.
Topics: Adrenergic alpha-Antagonists; Aged; Blood Pressure; Drug Interactions; Ethambutol; Female; Humans; H | 1992 |
Influence of mild to moderate treated hypertension on 9-11 year mortality in patients with pre-existing coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Aspirin; Cohort Studies; Coronary Disease; Female; Humans; Hyper | 1992 |
[Effect of nifedipine treatment on the renin-aldosterone system and secretion of cortisol and growth hormone in patients with essential hypertension].
Topics: Adult; Aldosterone; Female; Growth Hormone; Humans; Hydrocortisone; Hypertension; Male; Middle Aged; | 1991 |
Calcium, calcium antagonism, atherosclerosis, and ischemia.
Topics: Animals; Arteriosclerosis; Calcium; Coronary Disease; Cytosol; Humans; Hypercholesterolemia; Hyperte | 1992 |
Effects of nifedipine-GITS on left ventricular mass and left ventricular filling.
Topics: Atrial Natriuretic Factor; Cardiomegaly; Chlorthalidone; Delayed-Action Preparations; Drug Therapy, | 1992 |
Metabolic and antihypertensive effects of nifedipine in hypertensive patients.
Topics: Adult; Blood Pressure; Body Mass Index; Electrolytes; Female; Heart Rate; Humans; Hypertension; Male | 1992 |
Combined effect of dietary calcium and calcium antagonists on blood pressure reduction in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Calcium, Dietary; Hypertension; Male; Nifedipine; | 1992 |
Combination of nifedipine and doxazosin in essential hypertension.
Topics: Aged; Analysis of Variance; Angiotensin II; Antihypertensive Agents; Blood Pressure; Doxazosin; Drug | 1992 |
Antihypertensive mechanism of amlodipine in essential hypertension: role of pressor reactivity to norepinephrine and angiotensin II.
Topics: Adult; Amlodipine; Angiotensin II; Antihypertensive Agents; Blood Pressure; Body Weight; Dose-Respon | 1992 |
[The association of amlodipine with isosorbide-5-mononitrate in the treatment of ischemic-hypertensive cardiopathy].
Topics: Adult; Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Coronary Disease; Drug Evaluat | 1992 |
Dietary sodium and the antihypertensive effect of nifedipine in spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Heart Ventricles; Hemodynamics; | 1992 |
[Pulsed Doppler study of left ventricular diastolic function and intervention by nifedipine in hypertension].
Topics: Adult; Aged; Diastole; Echocardiography, Doppler; Female; Humans; Hypertension; Male; Middle Aged; N | 1992 |
[Changes in the activity of antioxidant enzymes in patients with hypertension].
Topics: Adult; Aged; Antioxidants; Enzyme Activation; Female; Glutathione Peroxidase; Humans; Hypertension; | 1992 |
[Comparative study of the action of Finoptin, Korinfar and Capoten in patients with stage II hypertensive disease].
Topics: Adult; Aged; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Contraction; Nif | 1992 |
[Acute and chronic hypotensive effect of m-nifedipine].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Isomerism; Male; Nifedip | 1992 |
Higher salt consumption, digoxin-like factor, and nifedipine response are associated with salt sensitivity in essential hypertension.
Topics: Adult; Blood Pressure; Blood Proteins; Cardenolides; Diet, Sodium-Restricted; Digoxin; Female; Human | 1992 |
[The dynamics of the concentration of atrial natriuretic factor depending on changes in the arterial pressure level in patients with arterial hypertension].
Topics: Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Captopril; Chronic Disease; Humans; Hydrochl | 1992 |
[The effect of long-term therapy with a calcium antagonist on thrombocyte function in hypertension patients].
Topics: Adenosine Diphosphate; Blood Platelets; Hemodynamics; Humans; Hypertension; Lasers; Male; Middle Age | 1992 |
Ascending aorta distensibility abnormalities in hypertensive patients and response to nifedipine administration.
Topics: Adult; Aorta; Echocardiography; Elasticity; Humans; Hypertension; Male; Middle Aged; Nifedipine; Reg | 1992 |
Microcirculation in systemic hypertension.
Topics: Adult; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Capillary Permeability; Female; Humans; | 1992 |
Severe hypotension with enalapril.
Topics: Administration, Oral; Administration, Sublingual; Drug Therapy, Combination; Enalapril; Humans; Hype | 1992 |
[The effect of korinfar and anaprilin on lipid peroxidation and the antioxidant system in hypertension patients].
Topics: Adult; Antioxidants; Drug Therapy, Combination; Female; Humans; Hypertension; Lipid Peroxidation; Li | 1992 |
Effects of angiotensin converting enzyme inhibitors and calcium antagonists on atrial natriuretic peptide release and action and on albumin excretion rate in hypertensive insulin-dependent diabetic patients.
Topics: Adult; Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Calcium Cha | 1992 |
Hypotensive drugs and the cellular energetic potential.
Topics: Antihypertensive Agents; Clonidine; Humans; Hypertension; Nifedipine; Phosphates; Propranolol; Water | 1992 |
Management of the cardiovascular manifestations of poisoning by the Indian red scorpion (Mesobuthus tamulus).
Topics: Adult; Aged; Animals; Cardiovascular Diseases; Child; Child, Preschool; Drug Therapy, Combination; F | 1992 |
[Changes in the humoral systems in juvenile arterial hypertension and their correction by using nifedipine and anaprilin].
Topics: Adolescent; Aldosterone; Angiotensin II; Blood Pressure; Drug Evaluation; Humans; Hypertension; Nife | 1992 |
[Calcium antagonists have a favorable long-term effect on lipid metabolism. Dr. K. P. Pollack presents results of his studies. Interview by Christine Schaefer].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension; Lipids; Nifedipine | 1992 |
[The calcium antagonist isradipine (Lomir) in the treatment of patients with essential hypertension].
Topics: Adult; Aged; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Drug Tole | 1992 |
Nifedipine induced reversible gingival hyperplasia.
Topics: Female; Gingival Hyperplasia; Humans; Hypertension; India; Middle Aged; Nifedipine | 1992 |
[The efficacy of a 4-year course of drug treatment for patients with juvenile hypertension].
Topics: Adolescent; Adult; Drug Evaluation; Drug Resistance; Hemodynamics; Humans; Hypertension; Nifedipine; | 1992 |
[The effect of nifedipine on arterial pressure and exercise tolerance in hypertensive patients].
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Drug Evaluation; Exercise Tolerance; Heart Rate; | 1992 |
Sublingual captopril and nifedipine in immediate treatment of hypertensive emergencies.
Topics: Administration, Sublingual; Captopril; Emergencies; Humans; Hypertension; Nifedipine | 1992 |
[Metabolic consequences of long-term antihypertensive treatment with co-dergocrine mesylate/nifedipine in high age groups].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Cholesterol; Drug Combinations; Ergoloid Mesylates; F | 1992 |
The effect of nifedipine and dipyridamole on the Doppler blood flow waveforms of umbilical and uterine arteries in hypertensive pregnant women.
Topics: Adult; Arteries; Blood Flow Velocity; Dipyridamole; Female; Humans; Hypertension; Nifedipine; Pregna | 1992 |
[Nifedipine infusions are effective in transient hypertension in small children and infants].
Topics: Age Factors; Child, Preschool; Emergencies; Female; Humans; Hypertension; Infant; Infusions, Intrave | 1992 |
[Comparison of the hemodynamic effects of Corinfar in patients with neurocirculatory dystonia and hypertensive disease].
Topics: Adolescent; Adult; Echocardiography; Hemodynamics; Humans; Hypertension; Middle Aged; Neurocirculato | 1992 |
Nifedipine in divided doses does not reverse left ventricular hypertrophy in spontaneously hypertensive rats.
Topics: Adrenergic Fibers; Animals; Blood Pressure; Body Weight; Cardiac Output; Cardiomegaly; Drug Administ | 1992 |
Differential effects of nifedipine on plasma atrial natriuretic peptide in normal subjects and hypertensive patients.
Topics: Adult; Aged; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Electrocardiography; Female; H | 1992 |
[24-hour protection and control: a new era of calcium antagonists. Amlodipine provides 24 hours of efficacy and safety].
Topics: Amlodipine; Calcium Channel Blockers; Circadian Rhythm; Coronary Disease; Humans; Hypertension; Nife | 1992 |
Pharmacokinetics and pharmacodynamics of amlodipine.
Topics: Amlodipine; Antihypertensive Agents; Calcium Channel Blockers; Half-Life; Humans; Hypertension; Nife | 1992 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitors; Calcium Channel | 1992 |
[Are all calcium antagonists alike?].
Topics: Calcium Channel Blockers; Coronary Disease; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1992 |
The role of renal hemodynamics in the antihypertensive action of mepirodipine, a new calcium antagonist.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Forearm; Hemodynamics; Hum | 1992 |
[Sexual impotence caused by nifedipine].
Topics: Erectile Dysfunction; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1992 |
Effects of nifedipine and moxonidine on cardiac structure in spontaneously hypertensive rats. Stereological studies on myocytes, capillaries, arteries, and cardiac interstitium.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Coronary Circulation; Heart; Hyperten | 1992 |
Sublingual nicardipine versus nifedipine to treat hypertensive urgencies.
Topics: Administration, Sublingual; Adult; Blood Pressure; Emergencies; Female; Heart Rate; Humans; Hyperten | 1992 |
MAOIs and hypertension.
Topics: Administration, Sublingual; Humans; Hypertension; Monoamine Oxidase Inhibitors; Nifedipine | 1992 |
Oral antihypertensive agent.
Topics: Administration, Oral; Antihypertensive Agents; Emergencies; Humans; Hypertension; Infusions, Intrave | 1992 |
Oral nifedipine in the treatment of hypertensive crises in patients with hypertensive encephalopathy.
Topics: Administration, Oral; Adult; Antihypertensive Agents; Brain Diseases; Female; Humans; Hypertension; | 1992 |
Tissue plasminogen activator in essential hypertension.
Topics: Adult; Blood Pressure; Humans; Hypertension; Middle Aged; Nifedipine; Tissue Plasminogen Activator | 1992 |
Is sublingual nifedipine administration superior to oral administration in the active treatment of hypertension?
Topics: Acute Disease; Administration, Oral; Administration, Sublingual; Drug Evaluation; Emergencies; Femal | 1992 |
Accelerated hypertension caused by severe phimosis.
Topics: Adolescent; Atenolol; Blood Pressure; Humans; Hypertension; Male; Nifedipine; Phimosis; Urination Di | 1992 |
Oral nifedipine pharmacokinetics in pregnancy-induced hypertension.
Topics: Administration, Oral; Adult; Female; Half-Life; Humans; Hypertension; Metabolic Clearance Rate; Nife | 1992 |
[The use of intravenous nifedipine for the treatment of severe hypertensive crisis. A clinical case].
Topics: Anesthesia; Humans; Hypertension; Injections, Intravenous; Nifedipine; Severity of Illness Index | 1992 |
Impaired myogenic responsiveness of renal microvessels in Dahl salt-sensitive rats.
Topics: Animals; Arteries; Arterioles; Blood Pressure; Diet, Sodium-Restricted; Female; Homeostasis; Hydrone | 1992 |
Nocturnal blood pressure monitored by ambulatory blood pressure measurement in elderly hypertensive patients.
Topics: Aged; Blood Pressure; Blood Pressure Determination; Cerebral Infarction; Circadian Rhythm; Diabetes | 1992 |
Comparison of converting enzyme inhibitor and calcium channel blocker in SHR with nephrotoxic serum nephritis.
Topics: Analysis of Variance; Animals; Antibodies, Heterophile; Basement Membrane; Captopril; Glomerulonephr | 1992 |
Captopril improves impaired endothelium-dependent vasodilation in hypertensive patients.
Topics: Acetylcholine; Adult; Aged; Blood Pressure; Captopril; Endothelium, Vascular; Female; Forearm; Human | 1992 |
Increased calcium influx in caudal artery of rats made hypertensive with pyridoxine deficiency.
Topics: Animals; Arteries; Biological Transport, Active; Calcium; Calcium Channels; Egtazic Acid; Hypertensi | 1991 |
Responsiveness of peripheral veins to vasodilators and the effect of nifedipine on alpha-adrenergic responsiveness in hypertension.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Dose-Response Relationship, Drug; Female; Hand; Huma | 1991 |
Pressor actions of arginine vasopressin in pithed Sprague-Dawley, Wistar-Kyoto and spontaneously hypertensive rats before and after treatment with nifedipine or pertussis toxin.
Topics: Animals; Arginine Vasopressin; Decerebrate State; Dose-Response Relationship, Drug; Hypertension; Ma | 1991 |
[The characteristics of the cerebral circulation in arterial hypertension].
Topics: Blood Flow Velocity; Carotid Arteries; Carotid Artery Diseases; Cerebrovascular Circulation; Humans; | 1991 |
Nifedipine and hypotension.
Topics: Humans; Hypertension; Hypotension; Male; Middle Aged; Nifedipine | 1991 |
Sublingual nifedipine for hypertensive emergencies.
Topics: Administration, Sublingual; Cerebrovascular Disorders; Contraindications; Emergencies; Humans; Hyper | 1991 |
Acute effects of combined alpha/beta-adrenoceptor blockade v combined beta-receptor and slow channel calcium blockade in ischemic heart disease complicated by hypertension. Hemodynamic and adrenergic responses.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Calcium Channel Blockers; Cardiac Output; | 1991 |
Sublingual nifedipine.
Topics: Administration, Sublingual; Emergencies; Humans; Hypertension; Nifedipine | 1991 |
Differential effects of antihypertensive agents on proliferation of vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Animals; Cell Division; Cells, Cultured; Hypertension; Male; Muscle, S | 1991 |
Increased vascular reactivity to Bay K 8644 in genetic hypertension.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
Role of blood pressure in the natriuretic response to acute calcium channel blockade in humans.
Topics: Blood Pressure; Calcium Channels; Female; Humans; Hypertension; Kidney; Kidney Tubules, Distal; Kidn | 1991 |
Effects of long-term blood pressure control on left and right ventricular structure and function in hypertensive patients.
Topics: Blood Pressure; Captopril; Cardiomegaly; Echocardiography; Echocardiography, Doppler; Female; Heart | 1991 |
Effect of nifedipine GITS on left ventricular mass and diastolic function in severe hypertension.
Topics: Blood Pressure; Delayed-Action Preparations; Humans; Hypertension; Middle Aged; Nifedipine; Ventricu | 1991 |
Protective effects of calcium antagonists on energy and substrate metabolism during ischemia and reperfusion in hypertensive myocardial hypertrophy.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Cardiomegaly; Energy Metabolism; Hyperten | 1991 |
Remodeling of left ventricular geometry and function induced by lacidipine and nifedipine SR in mild-to-moderate hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Dihydropyridines; Hear | 1991 |
Nifedipine: use of an oral antihypertensive agent in the emergency department setting.
Topics: Administration, Oral; Adult; Emergencies; Emergency Service, Hospital; Female; Humans; Hypertension; | 1992 |
Hemodynamic effects of the vascular selective calcium antagonist felodipine in patients with impaired left ventricular function.
Topics: Coronary Disease; Felodipine; Heart Failure; Hemodynamics; Humans; Hypertension; Myocardial Contract | 1992 |
Intravenously administered labetalol for treatment of hypertension in children.
Topics: Adolescent; Child; Child, Preschool; Creatinine; Diazoxide; Heart Rate; Humans; Hydralazine; Hyperte | 1992 |
Gordon's syndrome--hypertension and hyperkalemia associated with normal glomerular filtration rate.
Topics: Adult; Furosemide; Glomerular Filtration Rate; Humans; Hyperkalemia; Hypertension; Male; Nifedipine; | 1992 |
Transcranial Doppler to evaluate the effects of antihypertensive medication on cerebral blood flow velocity.
Topics: Aged; Blood Flow Velocity; Blood Pressure; Cerebrovascular Circulation; Female; Humans; Hypertension | 1992 |
Abnormal renal hemodynamics in black salt-sensitive patients with hypertension.
Topics: Analysis of Variance; Black People; Blood Pressure; Glomerular Filtration Rate; Heart Rate; Hemodyna | 1991 |
Verapamil and nifedipine in combination for the treatment of hypertrophy heart disease.
Topics: Adrenal Gland Diseases; Blood Pressure; Cardiovascular Diseases; Drug Therapy, Combination; Humans; | 1991 |
Priapism in haemodialysis patient due to prazosin?
Topics: Adult; Drug Therapy, Combination; Heparin; Humans; Hypertension; Male; Methyldopa; Nifedipine; Prazo | 1991 |
Ambulatory blood pressure monitoring in elderly hypertensives treated with the new calcium antagonist, nilvadipine.
Topics: Aged; Aged, 80 and over; Ambulatory Care; Blood Pressure; Blood Pressure Determination; Calcium Chan | 1991 |
Prevalence of persistent cough during long-term enalapril treatment: controlled study versus nifedipine.
Topics: Cough; Enalapril; Female; Humans; Hypertension; Larynx; Male; Middle Aged; Nifedipine; Prevalence; T | 1991 |
Effects of nifedipine and moxonidine on cardiac structure in spontaneously hypertensive rats (SHR)--stereological studies on myocytes, capillaries, arteries, and cardiac interstitium.
Topics: Animals; Blood Pressure; Drug Evaluation, Preclinical; Heart; Hypertension; Imidazoles; Male; Myocar | 1991 |
Safer use of MAOIs with nifedipine to counteract potential hypertensive crisis.
Topics: Administration, Sublingual; Humans; Hypertension; Monoamine Oxidase Inhibitors; Nifedipine | 1991 |
[The comparative efficacy and prognosis of the long-term treatment with korinfar of men and women suffering from hypertension].
Topics: Adult; Calcium Channel Blockers; Chronic Disease; Dose-Response Relationship, Drug; Drug Evaluation; | 1991 |
[The effect of prazosin and korinfar on the central hemodynamics and liver blood flow in hypertension patients (based on 2-dimensional Doppler echography)].
Topics: Adolescent; Adult; Dose-Response Relationship, Drug; Drug Evaluation; Female; Hemodynamics; Humans; | 1991 |
Nifedipine-induced depression.
Topics: Aged; Depressive Disorder; Dexamethasone; Humans; Hydrocortisone; Hypertension; Male; Nifedipine | 1991 |
[The effects of lowering of blood pressure on pain sensitivity in spontaneously hypertensive rats].
Topics: Animals; Blood Pressure; Hypertension; Indans; Male; Nifedipine; Pain; Pain Measurement; Rats; Rats, | 1991 |
[Uric acid and arterial hypertension. III. Effect of nifedipine on serum uric acid level and its renal excretion in primary arterial hypertension].
Topics: Adult; Diuresis; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nifedipine; Time Factors; | 1991 |
Efficacy of intravenous verapamil in arterial hypertension refractory to three-step antihypertensive therapy.
Topics: Adult; Antihypertensive Agents; Clonidine; Echocardiography; Female; Hemodynamics; Humans; Hydrochlo | 1991 |
[The use of sublingual nifedipine in pediatric hypertensive patients at the Hospital de la Capital].
Topics: Administration, Sublingual; Adolescent; Capsules; Child; Drug Evaluation; Hospitals, General; Humans | 1991 |
[Changes in circulating endothelial cells in patients with essential hypertension].
Topics: Adult; Aged; Blood Pressure; Cell Count; Endothelium, Vascular; Female; Fluorescent Antibody Techniq | 1991 |
Nifedipine concentrations in maternal and umbilical serum, amniotic fluid, breast milk and urine of mothers and offspring.
Topics: Administration, Oral; Adult; Amniotic Fluid; Female; Fetal Blood; Humans; Hypertension; Maternal-Fet | 1991 |
[Effect of the root canal surgery on blood pressure of the aged and its prevention].
Topics: Aged; Aged, 80 and over; Blood Pressure; Dental Pulp Cavity; Female; Humans; Hypertension; Male; Mid | 1991 |
Vascular injury: mechanisms and manifestations.
Topics: Amlodipine; Animals; Aorta, Thoracic; Arteriosclerosis; Calcium; Calcium Channel Blockers; Cardiomeg | 1991 |
Negative inotropic activity of the calcium antagonists isradipine, nifedipine, diltiazem, and verapamil in diseased human myocardium.
Topics: Antihypertensive Agents; Calcium Channel Blockers; Depression, Chemical; Diltiazem; Dose-Response Re | 1991 |
[Antihypertensive effects of amlodipine, a new calcium antagonist].
Topics: Administration, Oral; Amlodipine; Animals; Calcium Channel Blockers; Dogs; Dose-Response Relationshi | 1991 |
Impaired venoarteriolar reflex as a possible cause for nifedipine-induced ankle oedema.
Topics: Adult; Angioedema; Ankle; Arterioles; Blood Pressure; Diabetic Neuropathies; Female; Humans; Hyperte | 1991 |
Inhibition of erythrocyte membrane Ca(2+)-pumping ATPase of hypertensive humans by nifedipine, a calcium entry blocker.
Topics: Ca(2+) Mg(2+)-ATPase; Calcium Channel Blockers; Calcium-Transporting ATPases; Erythrocyte Membrane; | 1991 |
[Structural-functional state of the hypertensive heart and atrial natriuretic factor during treatment with nifedipine].
Topics: Adult; Aged; Atrial Natriuretic Factor; Echocardiography; Female; Heart; Humans; Hypertension; Male; | 1991 |
Photodermatitis due to nifedipine: report of 2 cases.
Topics: Aged; Drug Eruptions; Female; Humans; Hypertension; Middle Aged; Nifedipine; Photosensitivity Disord | 1991 |
Long-term haemodynamic effects of amlodipine at rest and during exercise in essential hypertension.
Topics: Adult; Amlodipine; Calcium Channel Blockers; Drug Administration Schedule; Female; Heart; Heart Rate | 1991 |
The effects of the calcium antagonist amlodipine on blood pressure and platelet aggregation in hypertensive patients.
Topics: Amlodipine; Calcium Channel Blockers; Drug Administration Schedule; Exercise Test; Female; Heart Rat | 1991 |
Circadian variation in blood pressure: considerations for therapy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Calcium Channel B | 1991 |
[Transient subendocardial ischemia in abolition of hypertensive crises with nifedipine].
Topics: Adult; Aged; Blood Pressure; Cardiomegaly; Coronary Disease; Echocardiography; Electrocardiography; | 1991 |
Acute, chronic and postwithdrawal antihypertensive and renal effects of amlodipine in hypertensive patients.
Topics: Amlodipine; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Heart Rate; Humans | 1991 |
[The effect of lowered pressure on the diastolic ventricular function after antihypertensive treatment].
Topics: Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Cardiomegaly; Diastole; Female; | 1991 |
[Sublingual captopril versus nifedipine in the treatment of hypertensive crisis].
Topics: Administration, Sublingual; Analysis of Variance; Blood Pressure; Captopril; Female; Heart Rate; Hum | 1991 |
Effect of plasma from patients with essential hypertension on vascular resistance in the isolated perfused rat kidney.
Topics: Adult; Angiotensin II; Animals; Blood Pressure; Chromatography, Gel; Female; Humans; Hypertension; I | 1991 |
[Pulmonary hemodynamics in patients with hypertension during acute drug tests using obsidan and corinfar].
Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Hypertension, Pulmonary; Male; Middle Aged; Nifed | 1991 |
Significant cost-saving with modification of antihypertensive therapy.
Topics: Adult; Aged; Aged, 80 and over; Amiloride; Antihypertensive Agents; Cost Control; Female; Humans; Hy | 1991 |
Interactions of clonidine and nifedipine in moderately severe hypertensive patients.
Topics: Blood Pressure; Clonidine; Delayed-Action Preparations; Drug Interactions; Drug Therapy, Combination | 1991 |
[Therapy of hypertensive coronary patients. Open long-term study with a combination of atenolol and nifedipine].
Topics: Aged; Atenolol; Coronary Disease; Drug Therapy, Combination; Exercise Test; Female; Humans; Hyperten | 1991 |
Nifedipine-induced gum hyperplasia.
Topics: Adult; Female; Gingival Hyperplasia; Humans; Hypertension; Nifedipine | 1991 |
Nifedipine-induced gingival hyperplasia.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Female; Gingival Hyperplasia; Humans; Hypertension; Male; | 1991 |
[Essential hypertension. Treatment with nifedipine and levels of insulin, glucagon, gastrin and prolactin].
Topics: Adult; Female; Gastrins; Glucagon; Humans; Hypertension; Insulin; Male; Middle Aged; Nifedipine; Pro | 1991 |
Nifedipine increases urinary excretion of prostacyclin metabolite in hypertensive pregnancy.
Topics: 6-Ketoprostaglandin F1 alpha; Adult; Blood Pressure; Catecholamines; Creatinine; Dinoprostone; Epopr | 1991 |
Effects of antihypertensive drugs on intracranial hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Brain Edema; Cerebral Hemorrhage; Cerebrospina | 1991 |
Hemodynamic comparison of two nifedipine formulations in patients with essential hypertension.
Topics: Capsules; Delayed-Action Preparations; Echocardiography; Female; Hemodynamics; Humans; Hypertension; | 1991 |
Effect of nifedipine tablets on ambulatory blood pressure in patients aged less than 60 and greater than 65 years with systemic hypertension.
Topics: Aged; Aging; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Dose-Response Relationship, | 1991 |
Hypoglycemia associated with the administration of angiotensin-converting enzyme inhibitor in a diabetic hemodialysis patient.
Topics: Adult; Captopril; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Enalapril; Humans; Hypertension | 1991 |
Nifedipine: bite-and-swallow administration.
Topics: Administration, Oral; Capsules; Humans; Hypertension; Monoamine Oxidase Inhibitors; Nifedipine | 1991 |
[Hemodynamic comparison of intravenous nitroprusside and nifedipine for the control of arterial hypertension after cardiac surgery interventions].
Topics: Coronary Artery Bypass; Heart Valves; Hemodynamics; Humans; Hypertension; Injections, Intravenous; N | 1991 |
Sustained calcium channel blockade in the treatment of severe hypertension. A two year experience.
Topics: Adult; Calcium Channels; Echocardiography; Female; Heart Ventricles; Humans; Hypertension; Male; Mid | 1990 |
Safer use of MAOIs.
Topics: Administration, Sublingual; Depressive Disorder; Drug Interactions; Food; Humans; Hypertension; Mono | 1991 |
Captopril attenuates reflex adrenergic response in essential hypertension.
Topics: Administration, Oral; Adult; Aldosterone; Blood Pressure; Captopril; Female; Hemodynamics; Humans; H | 1991 |
Evaluation of drug therapy for treatment of hypertensive urgencies in the emergency department.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clonidine; Drug Therapy; Emergency Service, Hospital; Evalu | 1991 |
Treatment of hypertensive crisis.
Topics: Antihypertensive Agents; Cerebrovascular Disorders; Emergencies; Humans; Hypertension; Nifedipine; N | 1991 |
[Effects of nifedipine, in primary hypertension, on calcium metabolism and on the excretion of the main urinary electrolytes].
Topics: Calcium; Electrolytes; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1991 |
Combined use of nifedipine and diltiazem for the treatment of severe hypertension.
Topics: Aged; Diltiazem; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Humans; Hy | 1991 |
Gastric absorption of nifedipine.
Topics: Absorption; Acute Disease; Administration, Oral; Administration, Sublingual; Humans; Hypertension; M | 1991 |
Clinical significance of ambulatory blood pressure monitoring. Evaluation of severity of hypertension, efficacy of treatment and effects on nighttime blood pressure.
Topics: Blood Pressure Determination; Blood Pressure Monitors; Circadian Rhythm; Delayed-Action Preparations | 1991 |
The effect of nifedipine GITS on renal function in hypertensive patients with renal insufficiency.
Topics: Blood Pressure; Delayed-Action Preparations; Female; Glomerular Filtration Rate; Humans; Hypertensio | 1991 |
[Echocardiographic monitoring of treatment of mild hypertension using nifedipine].
Topics: Blood Pressure; Echocardiography; Humans; Hypertension; Male; Nifedipine; Vascular Resistance | 1991 |
Antihypertensive and diuretic effects of YM-09730-5, a new calcium antagonist, in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cerebrovascular Disorder | 1991 |
[The influence of changes in the blood pressure and plasma renin activity on the natriuretic effect of nifedipine].
Topics: Adult; Blood Pressure; Drug Evaluation; Female; Humans; Hypertension; Male; Middle Aged; Natriuresis | 1991 |
[The side effects of korinfar in hypertension patients].
Topics: Adult; Blood Pressure; Cerebrovascular Circulation; Chronic Disease; Drug Evaluation; Female; Humans | 1991 |
Effects of slow-release nifedipine on nighttime blood pressure.
Topics: Adult; Aged; Blood Pressure; Blood Pressure Monitors; Circadian Rhythm; Delayed-Action Preparations; | 1991 |
[Modification of the smoking-induced hemodynamic effect by nifedipine].
Topics: Calcium Channel Blockers; Catecholamines; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nif | 1991 |
Isolated T-wave abnormalities and evaluation of left ventricular wall motion after nifedipine for severe hypertension.
Topics: Echocardiography; Electrocardiography; Hemodynamics; Humans; Hypertension; Middle Aged; Movement; Ni | 1991 |
Effects of slow-release nifedipine on water-sodium, uric acid, and calcium metabolism, and on aldosterone secretion in patients with essential hypertension.
Topics: Aldosterone; Angiotensin II; Calcium; Delayed-Action Preparations; Humans; Hypertension; Nifedipine; | 1990 |
Comparison of the acute effects of captopril and of nifedipine on left ventricular diastolic function in elderly hypertensive patients.
Topics: Aged; Aged, 80 and over; Blood Pressure; Captopril; Diastole; Drug Therapy, Combination; Heart Rate; | 1990 |
[The clinical pharmacology and efficacy of the new Soviet calcium antagonist foridon].
Topics: Angina Pectoris; Calcium Channel Blockers; Coronary Disease; Drug Evaluation; Drug Therapy, Combinat | 1990 |
[The hemodynamic reactions of hypertension patients taking the calcium antagonists finoptin and korinfar].
Topics: Adult; Drug Evaluation; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedi | 1990 |
[Cardil (diltiazem) in the treatment of patients with ischemic heart disease and hypertension].
Topics: Coronary Disease; Diltiazem; Drug Evaluation; Hemodynamics; Humans; Hypertension; Nifedipine; Verapa | 1990 |
Acute haemodynamic effects of urapidil and nifedipine in hypertensive urgencies and emergencies.
Topics: Acute Disease; Aged; Aged, 80 and over; Antihypertensive Agents; Emergencies; Female; Heart Rate; He | 1990 |
[The role of therapy with a Ca++ antagonists (nifedipine) in the long-term prognosis of hypertensive patients with previous myocardial infarction].
Topics: Adult; Aged; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Myocardial Infarcti | 1990 |
Blood pressure, plasma renin activity and calcium metabolism in hypertensive pregnancy: the effect of nifedipine.
Topics: Adult; Blood Pressure; Calcium; Electrolytes; Female; Humans; Hypertension; Nifedipine; Pregnancy; P | 1990 |
[Arterial hypertension caused by low renin: comparison of the calcium antagonist nifedipine and the ACE-inhibitor enalapril as to antihypertensive efficacy].
Topics: Blood Pressure; Diabetes Mellitus, Type 2; Enalapril; Female; Humans; Hypertension; Male; Middle Age | 1990 |
[Intraerythrocyte levels of glucose-6-phosphate dehydrogenase in patients with essential arterial hypertension and persons with normal blood pressure. Modifications after nifedipine therapy].
Topics: Adult; Aged; Erythrocytes; Female; Glucosephosphate Dehydrogenase; Humans; Hypertension; Male; Middl | 1990 |
[Gingival hyperplasia and nifedipine].
Topics: Female; Gingival Hyperplasia; Humans; Hypertension; Middle Aged; Nifedipine | 1990 |
Marked gingival hyperplasia induced by nifedipine.
Topics: Female; Gingival Hyperplasia; Humans; Hypertension; Middle Aged; Nifedipine | 1990 |
Cardiovascular properties of LF 2.0254, a new potent vasoselective calcium channel blocker with a slow onset of action.
Topics: Anesthesia; Animals; Calcimycin; Calcium Channel Blockers; Calcium Chloride; Calcium Radioisotopes; | 1990 |
Significance of coronary circulation in hypertensive heart disease for development and prevention of heart failure.
Topics: Adult; Animals; Cardiac Output, Low; Cardiomegaly; Coronary Circulation; Coronary Disease; Coronary | 1990 |
Increased blood kynurenine level as a factor inhibiting the therapeutic effect of antihypertensive agents in combined long-term treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Cardiac Volume; Cardiomegaly; Clonidine; Drug Therap | 1990 |
Effects of amlodipine, a long-acting dihydropyridine calcium antagonist in aging hypertension: pharmacodynamics in relation to disposition.
Topics: Administration, Oral; Adult; Aged; Aging; Amlodipine; Atrial Natriuretic Factor; Blood Pressure; Cal | 1990 |
Long term reduction in sodium balance: possible additional mechanism whereby nifedipine lowers blood pressure.
Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Body Weight; Female; Humans; Hy | 1990 |
Protecting the vasculature: an eye toward the future.
Topics: Amlodipine; Animals; Arteries; Arteriosclerosis; Blood Pressure; Calcium Channel Blockers; Cerebrova | 1990 |
[Action of sublingual nifedipine on left ventricular filling in hypertensive crisis].
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Blood Pressure; Cardiomegaly; Echocardio | 1990 |
[Changes of Ca2(+)-ATPase and calmodulin in erythrocytes and their responses to nifedipine in essential hypertension].
Topics: Adult; Biological Transport, Active; Calcium; Calcium-Transporting ATPases; Calmodulin; Erythrocytes | 1990 |
Foridone and other calcium antagonists in the treatment of essential hypertension.
Topics: Antihypertensive Agents; Binding, Competitive; Blood Pressure; Calcium Channel Blockers; Calcium Cha | 1990 |
Comparison of sublingual captopril and sublingual nifedipine in hypertensive emergencies.
Topics: Administration, Sublingual; Blood Pressure; Captopril; Emergencies; Female; Heart Rate; Humans; Hype | 1990 |
Calcium channel blockers reverse the sustained elevation of blood pressure induced by chronic infusion of endothelin in conscious rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Endothelins; Hypertension; Male | 1990 |
Uterine and fetal flow velocity waveforms in hypertensive pregnancy: the effect of a single dose of nifedipine.
Topics: Adult; Apgar Score; Birth Weight; Blood Flow Velocity; Cerebral Arteries; Cesarean Section; Female; | 1990 |
Acute effects of antihypertensive agents on cerebral blood flow in hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Gas Analysis; Captopril; Cerebral Cortex; Cerebrovascular Ci | 1990 |
Reactivity and sensitivity of mesenteric vascular beds and aortic rings of spontaneously hypertensive rats to endothelin: effects of calcium entry blockers.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Endothelins; Hypertension; In Vitro Techniques; | 1990 |
Use of tensiomin (captopril) in the antihypertensive treatment of haemodialysis patients.
Topics: Adult; Antihypertensive Agents; Captopril; Drug Therapy, Combination; Female; Guanfacine; Guanidines | 1990 |
Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin.
Topics: Angiotensin II; Animals; Blood Pressure; Endothelins; Endothelium, Vascular; Hypertension; Hypotensi | 1990 |
[Effects of chronic administration of nifedipine on echo-Doppler parameters of left ventricular filling in hypertensive patients].
Topics: Adult; Aged; Echocardiography, Doppler; Female; Heart Ventricles; Humans; Hypertension; Male; Middle | 1990 |
Effects of nifedipine and enalapril on glomerular injury in rats with deoxycorticosterone-salt hypertension.
Topics: Animals; Desoxycorticosterone; Enalapril; Hypertension; Kidney Glomerulus; Male; Nifedipine; Platele | 1990 |
[Evaluation of the effectiveness of calcium antagonists combined with digoxin and furosemide in hypertension complicated by circulatory insufficiency in elderly patients].
Topics: Aged; Digoxin; Drug Therapy, Combination; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertens | 1990 |
Effect of plasma from essential hypertensives on vascular tone of aortic strips, isolated perfused mesentery and isolated perfused kidney.
Topics: Adult; Angiotensin II; Animals; Aorta; Blood Pressure; Female; Hemodynamics; Humans; Hypertension; K | 1990 |
The effect of calcium channel blockers on the cyclosporine dose requirement in renal transplant recipients.
Topics: Adult; Calcium Channel Blockers; Cyclosporins; Drug Interactions; Drug Therapy, Combination; Female; | 1990 |
Increase in hematocrit by nifedipine in hypertensive patients.
Topics: Adult; Blood Pressure; Blood Proteins; Female; Heart Rate; Hematocrit; Humans; Hypertension; Male; N | 1990 |
[Evaluation of the efficacy and tolerability of sustained-release nifedipine in arterial hypertension. Continuous monitoring of arterial pressure].
Topics: Adult; Aged; Delayed-Action Preparations; Female; Humans; Hypertension; Middle Aged; Monitoring, Phy | 1990 |
Long term reduction in sodium balance.
Topics: Humans; Hypertension; Nifedipine; Sodium | 1990 |
Effects of nifedipine on diastolic function in hypertensive patients--an echocardiographic study.
Topics: Adult; Aged; Diastole; Echocardiography; Echocardiography, Doppler; Female; Hemodynamics; Humans; Hy | 1990 |
Long-term improvement in renal function using nifedipine in cyclosporine-associated hypertension.
Topics: Creatinine; Cyclosporins; Humans; Hypertension; Kidney; Kidney Transplantation; Nifedipine | 1990 |
Acute and long-term treatment of hypertension with nifedipine in the elderly.
Topics: Administration, Sublingual; Aged; Aged, 80 and over; Blood Pressure; Drug Evaluation; Female; Humans | 1990 |
Nifedipine induced hyperglycaemia.
Topics: Administration, Sublingual; Glucose Tolerance Test; Humans; Hyperglycemia; Hypertension; Male; Middl | 1990 |
[Depin-E in the treatment of hypertensive crises in patients with essential and secondary arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Evaluation; Fem | 1990 |
Effects of cromakalim, a potassium channel opener, on regional blood flow in conscious spontaneously hypertensive rats.
Topics: Animals; Benzopyrans; Blood Pressure; Cromakalim; Heart Rate; Hemodynamics; Humans; Hypertension; In | 1990 |
[Hypokalemia caused by nifedipine].
Topics: Aged; Clonidine; Drug Therapy, Combination; Female; Humans; Hypertension; Hypokalemia; Nifedipine | 1990 |
Vasodilators and hypertensive encephalopathy following scorpion envenomation in children.
Topics: Acute Disease; Animals; Brain Diseases; Child; Child, Preschool; Humans; Hydralazine; Hypertension; | 1990 |
Oral nifedipine in the treatment of hypertensive urgency: cerebrovascular accident following a single dose.
Topics: Adult; Cerebrovascular Disorders; Humans; Hypertension; Male; Nifedipine | 1990 |
DOCA-salt treatment decreases serum total calcium but not ionized calcium concentrations in rats.
Topics: Animals; Calcium; Desoxycorticosterone; Hypertension; Male; Nephrectomy; Nifedipine; Rats; Rats, Inb | 1990 |
[Acute hemodynamic changes after nifedipine in older men with essential hypertension].
Topics: Aged; Echocardiography; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1990 |
Dose adjustment of nifedipine in hypertensive patients.
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Dose-Response Relationship, Drug; Female; Humans | 1990 |
Haemodynamic resistance of forearm vessels during prolonged drug treatment of essential hypertension.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Therapy, Combination | 1990 |
Nifedipine as an antihypertensive drug in patients with renal failure--pharmacokinetics and effects.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Age | 1990 |
[Blood pressure lowering effect of nifedipine in smokers and non-smokers].
Topics: Antihypertensive Agents; Blood Pressure; Drug Evaluation; Female; Health Surveys; Humans; Hungary; H | 1990 |
Effect of plasma from essential hypertensives on tension of aortic strips.
Topics: Adult; Animals; Aorta; Blood Pressure; Calcium; Female; Humans; Hypertension; In Vitro Techniques; I | 1990 |
Prehospital use of nifedipine for severe hypertension.
Topics: Administration, Oral; Adult; Blood Pressure; Emergencies; Emergency Medical Services; Humans; Hypert | 1990 |
Effect of nifedipine on fetal heart rate in the treatment of severe pregnancy-induced hypertension.
Topics: Female; Heart Rate, Fetal; Humans; Hypertension; Nifedipine; Pregnancy; Pregnancy Complications, Car | 1990 |
[Nifedipine and molsidomine treatment of circulatory insufficiency in elderly patients with hypertension].
Topics: Age Factors; Aged; Aged, 80 and over; Cardiac Glycosides; Diuretics; Drug Evaluation; Drug Therapy, | 1990 |
Effects of nifedipine SR and enalapril on office, home and ambulatory blood pressure in "white-coat" systemic hypertension.
Topics: Adult; Aged; Blood Pressure Determination; Enalapril; Female; Humans; Hypertension; Male; Middle Age | 1990 |
Regression of cardiac hypertrophy after therapy in animal hypertension.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Cardiomegaly; Hypertension; Nifedipine; Rats; Rats | 1985 |
Chronic treatment with nifedipine prevents development of hypertension and abnormal red cell Na+ transport in Dahl-S-rats.
Topics: Animals; Bumetanide; Erythrocyte Membrane; Erythrocytes; Female; Hypertension; In Vitro Techniques; | 1985 |
Decreased [3H]nitrendipine binding in the brainstem of deoxycorticosterone-NaCl hypertensive rats.
Topics: Animals; Brain Stem; Calcium; Desoxycorticosterone; Dihydropyridines; Hypertension; Ion Channels; Ki | 1985 |
An investigation of alpha-adrenoceptor responsiveness in the vas deferens of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1985 |
Calcium channel blocking drugs. Part II: Clinical applications.
Topics: Angina Pectoris; Angina Pectoris, Variant; Angina, Unstable; Arrhythmias, Cardiac; Calcium Channel B | 1985 |
Adrenoceptors, calcium, and vasoconstriction in normal and hypertensive humans.
Topics: Arm; Blood Platelets; Blood Pressure; Calcium; Cytoplasm; Humans; Hypertension; Nifedipine; Nitrendi | 1985 |
Increased cardiovascular responses to norepinephrine and calcium antagonists in essential hypertension compared with normotension in humans.
Topics: Adult; Angiotensin II; Calcium Channel Blockers; Diltiazem; Hemodynamics; Humans; Hypertension; Male | 1985 |
Does nifedipine reveal a functional abnormality of arteriolar smooth muscle cell in essential hypertension--the effect of altering sodium balance.
Topics: Arterioles; Calcium; Diuretics; Humans; Hypertension; Muscle, Smooth, Vascular; Nifedipine; Sodium; | 1985 |
Effect of felodipine on resistance vessels from spontaneously hypertensive and normotensive rats.
Topics: Animals; Calcium; Felodipine; Hypertension; Muscle Contraction; Nifedipine; Norepinephrine; Rats; Ra | 1985 |
Interference of the calcium antagonist nisoldipine with the abnormal response of vessels from hypertensive rats to alpha-adrenergic stimulation.
Topics: Adrenergic alpha-Agonists; Animals; Azepines; Hypertension; In Vitro Techniques; Male; Muscle Contra | 1985 |
[Changes in serum levels of ionic calcium during the treatment of hypertensive emergencies with nifedipine].
Topics: Adult; Aged; Biological Transport, Active; Blood Pressure; Calcium; Calmodulin; Humans; Hypertension | 1985 |
Increased Ca2+ sensitivity of alpha 1-adrenoceptor-stimulated contraction in SHR caudal artery.
Topics: Animals; Arteries; Calcium; Dose-Response Relationship, Drug; Drug Resistance; Hypertension; Ion Cha | 1986 |
Enalapril in experimental hypertension and acute heart failure: comparison with calcium channel blockers.
Topics: Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; D | 1986 |
Effects of Bay K 8644 and nifedipine on femoral arteries of spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Contractile effects of Bay k 8644, a dihydropyridine calcium agonist, on isolated femoral arteries from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Calcium metabolism, renin activity, and the antihypertensive effects of calcium channel blockade.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Humans; Hypertension; Ion Channels; Nifedipine; R | 1986 |
Reduced alpha 1-adrenoreceptor mediated responsiveness in vas deferens from spontaneously hypertensive rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Pharmacokinetics and hemodynamic effects of long-term nifedipine treatment in hypertensive patients.
Topics: Adult; Aged; Blood Pressure; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Kinetics; M | 1987 |
Renal clearance and micropuncture studies of nisoldipine effects in spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Glomerular Filtration Rate; Hypertension; Kidney; | 1987 |
Nifedipine does not blunt the aldosterone and cardiovascular response to angiotensin II and potassium infusion in hypertensive patients.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Blood Pressure; Drug Interactions; Female; Heart Rate; Hem | 1988 |
[Effect of nifedipine on the cationic profile of myocardium and skeletal muscle of normal and hypertensive rats].
Topics: Animals; Blood Pressure; Body Weight; Cations; Hypertension; Ion Channels; Male; Muscles; Myocardium | 1987 |
Hormonal and renal responses to oral once-daily calcium entry blocker in normotensive and hypertensive persons.
Topics: Adult; Aldosterone; Angiotensin II; Calcium Channel Blockers; Dopamine; Epinephrine; Female; Hemodyn | 1988 |
Effects of different sodium intakes on the antihypertensive and renal effects of single oral doses of nifedipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Aldosterone; Blood Pressure; Diet, Sodium-Restricted; Furosemide; | 1987 |
Acute antihypertensive effect of nifedipine on high and low salt diet.
Topics: Adult; Blood Pressure; Humans; Hypertension; Nifedipine; Sodium; Sodium, Dietary | 1987 |
Acute natriuresis induced by inhibition of proximal tubular reabsorption of sodium and water in hypertensives following acute calcium entry blockade with nifedipine.
Topics: Blood Pressure; Body Water; Female; Glomerular Filtration Rate; Heart Rate; Humans; Hypertension; Ki | 1987 |
The effects of nifedipine and captopril on renal function in patients with essential hypertension: comparison with sodium nitroprusside.
Topics: Adult; Aged; Blood Pressure; Captopril; Female; Ferricyanides; Glomerular Filtration Rate; Heart Rat | 1987 |
Central hemodynamic effects at rest and during exercise of acute and chronic treatment with nisoldipine in essential hypertension.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Female; Heart Rate; Hemodynamics; H | 1987 |
Effect of calcium antagonists on hypertension and diabetes in new hypertensive diabetic models.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Disea | 1987 |
Changes in sensitivity to angiotensin II in platelets.
Topics: Administration, Oral; Adult; Angiotensin II; Blood Platelets; Blood Pressure; Calcium; Captopril; Fe | 1987 |
[Central control of the baroreflex response to phenylephrine by dihydropyridines in the anesthetized rat].
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
[Effect of long-term treatment with nifedipine on the activity of the sympathetic-adrenal system, lipids and beta-thromboglobulin in patients with primary arterial hypertension].
Topics: Adrenal Glands; Adult; Beta-Globulins; Blood Platelets; Humans; Hypertension; Lipids; Middle Aged; N | 1988 |
The effect of amlodipine on hypertension-induced cardiac hypertrophy and reperfusion-induced calcium overload.
Topics: Aging; Amlodipine; Animals; Blood Pressure; Calcium; Calcium Channel Blockers; Cardiomegaly; Coronar | 1988 |
Amlodipine in elderly hypertensive patients: pharmacokinetics and pharmacodynamics.
Topics: Adult; Aged; Aging; Amlodipine; Blood Pressure; Calcium Channel Blockers; Female; Half-Life; Hormone | 1988 |
Effects of nisoldipine on renal function in normal volunteers and essential hypertensive patients.
Topics: Adult; Blood Pressure; Body Weight; Diet, Sodium-Restricted; Glomerular Filtration Rate; Humans; Hyp | 1989 |
Pharmacokinetics and hemodynamic effects of long-term nisoldipine treatment in hypertensive patients.
Topics: Administration, Oral; Aged; Calcium Channel Blockers; Child; Hemodynamics; Humans; Hypertension; Inf | 1989 |
Regression of cardiac hypertrophy: experimental and clinical results.
Topics: Animals; Cardiomegaly; Clonidine; Enalapril; Humans; Hypertension; Nifedipine; Prazosin; Rats; Rats, | 1987 |
Nifedipine and/or atenolol for mild to moderate hypertension: a general practice study.
Topics: Atenolol; Delayed-Action Preparations; Drug Combinations; Humans; Hypertension; Nifedipine | 1989 |
Calcium antagonists in prevention of hypertension and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Animals; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Hypertension; Male; Nifedipine | 1989 |
[The effect of nitroglycerin ointment on cardiovascular functions in hypertensive patients during emergence from anesthesia].
Topics: Administration, Intranasal; Adult; Aged; Anesthesia Recovery Period; Blood Pressure; Humans; Hyperte | 1989 |
Effects of calcium antagonists and nitroglycerin on atrial natriuretic peptide in normal subjects and patients with essential hypertension.
Topics: Adult; Aged; Angiotensin II; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Fe | 1989 |
Left ventricular function and collagen content after regression of hypertensive hypertrophy.
Topics: Animals; Cardiomegaly; Collagen; Heart; Hydroxyproline; Hypertension; Nifedipine; Rats; Rats, Inbred | 1989 |
A case of atrial septal defect combined with hypertension and left ventricular hypertrophy. Left ventricular failure induced by balloon occlusion and the effect of nifedipine.
Topics: Blood Pressure; Cardiac Output, Low; Cardiomegaly; Catheterization; Female; Heart Septal Defects, At | 1989 |
Converting enzyme inhibition specifically prevents the development and induces regression of cardiac hypertrophy in rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bridged | 1989 |
[Nifedipine in the treatment of hypertension. An echocardiographic assessment of the hemodynamic effects].
Topics: Adult; Cardiomegaly; Drug Evaluation; Echocardiography; Heart; Hemodynamics; Humans; Hypertension; M | 1989 |
Regression of left ventricular hypertrophy by acebutolol and nifedipine.
Topics: Acebutolol; Blood Pressure; Cardiomegaly; Drug Combinations; Echocardiography; Humans; Hypertension; | 1989 |
[Pharmacological study on blood pressure in rats with bone disorders].
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bone Dis | 1989 |
Rapid haemodynamic response to adrenocorticotrophin and the role of peripheral resistance in adrenocorticotrophin-induced hypertension in conscious sheep.
Topics: Adrenocorticotropic Hormone; Animals; Calcium Channel Blockers; Consciousness; Female; Hemodynamics; | 1989 |
[Calcium antagonists vs ACE inhibitors in the treatment of essential arterial hypertension in the aged].
Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Dr | 1989 |
Decrease in alpha 1-adrenoceptor reserve in mesenteric arteries isolated from spontaneously hypertensive rats.
Topics: Adrenergic alpha-Agonists; Animals; Dose-Response Relationship, Drug; Hypertension; Male; Mesenteric | 1989 |
Hypertensive crisis during coronary vessel surgery.
Topics: Adrenergic beta-Antagonists; Coronary Artery Bypass; Coronary Disease; Coronary Vessels; Humans; Hyp | 1989 |
Studies on the role of sodium- and potassium-activated adenosine triphosphatase inhibition in the pathogenesis of human hypertension. Changes in vascular and cardiac function following inhibition of the sodium pump in normotensive subjects and effects of
Topics: Adenosine Triphosphate; Adult; Blood Pressure; Calcium; Erythrocytes; Hemodynamics; Humans; Hyperten | 1985 |
Effect of chronic nifedipine in patients inadequately controlled by a converting enzyme inhibitor and a diuretic.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Creatinine; Dipeptides; | 1985 |
Pressure-induced vasoconstriction of renal microvessels in normotensive and hypertensive rats. Studies in the isolated perfused hydronephrotic kidney.
Topics: Animals; Homeostasis; Hydronephrosis; Hypertension; In Vitro Techniques; Kidney; Microcirculation; N | 1989 |
[New approach to the development of Ca antagonists].
Topics: Animals; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Humans; Hypertension; Nic | 1989 |
[Calcium antagonists in the treatment of hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nicardipine; Nifedipine; Verapamil | 1989 |
Dosage of nifedipine in hypertensive crises of infants and children.
Topics: Acute Disease; Administration, Sublingual; Child; Child, Preschool; Dose-Response Relationship, Drug | 1989 |
[The use of calcium antagonists for treating hypertension].
Topics: Calcium Channel Blockers; Diltiazem; Humans; Hypertension; Nifedipine; Verapamil | 1989 |
Nifedipine in the treatment of hypertensive episodes in the coronary care unit.
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Coronary Care Units; Coronary Disease; Female; Human | 1989 |
[Comparative study of nifedipine and nicardipine in the treatment of hypertensive crisis after aortocoronary bypass].
Topics: Coronary Artery Bypass; Humans; Hypertension; Nicardipine; Nifedipine; Postoperative Complications | 1989 |
[Nifedipine and verapamil in the treatment of ischemic heart disease and hypertension].
Topics: Angina Pectoris; Coronary Disease; Dose-Response Relationship, Drug; Humans; Hypertension; Nifedipin | 1989 |
Effectiveness of long-acting nifedipine in pheochromocytoma.
Topics: Adrenal Gland Neoplasms; Blood Pressure; Delayed-Action Preparations; Epinephrine; Female; Humans; H | 1989 |
Plasma catecholamine and cardiovascular responses to nifedipine in hypertensives WHO-stage II.
Topics: Administration, Sublingual; Adult; Blood Pressure; Catecholamines; Epinephrine; Female; Heart; Heart | 1989 |
Treatment of hypertensive crises in neurosurgery.
Topics: Animals; Antihypertensive Agents; Cerebrovascular Circulation; Dogs; Hemodynamics; Humans; Hypertens | 1989 |
[The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension].
Topics: Aged; Calcium Channel Blockers; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug The | 1989 |
[Stress hemodynamics in hypertensive patients treated with nifedipine].
Topics: Adult; Blood Pressure; Cardiac Output; Electrocardiography; Exercise Test; Heart Rate; Hemodynamics; | 1989 |
Vasodilation in the vascular bed of skeletal muscle after intravenous nifedipine in normotensives and hypertensives.
Topics: Adult; Drug Evaluation; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Muscles; Ni | 1989 |
[M-echocardiographic determination of left-ventricular diastolic noncompliance, diastolic wall stress and the rate of relaxation of the circumferential muscle fibers].
Topics: Adult; Aged; Cardiomyopathy, Hypertrophic; Compliance; Coronary Disease; Diastole; Echocardiography; | 1989 |
Elevation of blood pressure in young rats fed a low calcium diet. Effects of nifedipine and captopril.
Topics: Animals; Blood Pressure; Body Weight; Calcium; Captopril; Diet; Disease Models, Animal; Heart Rate; | 1989 |
Hemodynamic and endocrine effects of acute and chronic administration of nifedipine.
Topics: Aldosterone; Arginine; Blood Pressure; Cardiac Output; Endocrine Glands; Female; Glucagon; Glycated | 1989 |
Therapy of venous hypertension in calves with total artificial heart (TAH).
Topics: Animals; Antihypertensive Agents; Captopril; Cardiac Pacing, Artificial; Cattle; Central Venous Pres | 1989 |
Decreased rectal body temperature induced by different vasodilatory drugs.
Topics: Adult; Epoprostenol; Female; Humans; Hypertension; Hypothermia; Middle Aged; Nifedipine; Prazosin; R | 1989 |
Insulin secretion and glucose tolerance in non-insulin dependent diabetic patients after chronic nifedipine treatment.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Hyperte | 1989 |
Effects of sublingual administration of nifedipine on arterial pressure, plasma renin activity, and glomerular filtration rate in essential hypertension.
Topics: Administration, Sublingual; Adult; Blood Pressure; Drug Evaluation; Female; Glomerular Filtration Ra | 1989 |
[Association of intracellular free calcium concentration in lymphocytes with acute hypotensive response to nifedipine in patients with essential hypertension].
Topics: Adult; Calcium; Female; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Nifedipine; Renin | 1989 |
Cyclosporine-associated hypertension in cardiopulmonary transplantation. The beneficial effect of nifedipine on renal function.
Topics: Adult; Cyclosporins; Heart Transplantation; Humans; Hypertension; Kidney; Lipids; Lung Transplantati | 1989 |
Captopril--nifedipine interaction in hypertension.
Topics: Adult; Aged; Captopril; Drug Interactions; Humans; Hypertension; Middle Aged; Nifedipine | 1989 |
Diabetogenic effect of nifedipine.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1989 |
[Tolerance to delayed-action nifedipine].
Topics: Aged; Aged, 80 and over; Delayed-Action Preparations; Drug Tolerance; Female; Humans; Hypertension; | 1989 |
Nisoldipine inhibition of sodium influx into aorta from aldosterone-salt-hypertensive rats.
Topics: Aldosterone; Animals; Aorta; Calcium; Calcium Channel Blockers; Hydrogen; Hypertension; Ion Exchange | 1989 |
[Nifedipine and epistaxis recurrence].
Topics: Epistaxis; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1989 |
[Clinico-pharmacologic study on the liquid form of nifedipine in treating hypertensive crisis].
Topics: Administration, Oral; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hypertension | 1989 |
[Modification of left ventricular filling after acute administration of nifedipine in hypertensive patients. Doppler echocardiographic study].
Topics: Adult; Aged; Diastole; Echocardiography; Female; Humans; Hypertension; Male; Middle Aged; Myocardial | 1989 |
Interrelationship between plasma ionized calcium, plasma noradrenaline (NA) and pressor response to infused NA in patients with essential hypertension.
Topics: Blood Pressure; Calcium; Humans; Hypertension; Infusions, Intravenous; Ions; Nifedipine; Norepinephr | 1989 |
[The effects of nifedipine on blood pressure and renal function].
Topics: Administration, Oral; Adult; Animals; Blood Pressure; Humans; Hypertension; Kidney; Kidney Diseases; | 1989 |
[Changes in central and cerebral hemodynamics in patients with hypertension after a single-dose administration of corinfar].
Topics: Adult; Aged; Antihypertensive Agents; Cerebrovascular Circulation; Female; Hemodynamics; Humans; Hyp | 1989 |
[Changes in cerebral circulation under the influence of korinfar in hypertension patients].
Topics: Adult; Aged; Cerebrovascular Circulation; Drug Evaluation; Female; Headache; Humans; Hypertension; M | 1989 |
Rectal nifedipine in acute severe hypertension in young children.
Topics: Administration, Rectal; Adolescent; Child; Child, Preschool; Humans; Hypertension; Nifedipine | 1989 |
Sublingual nifedipine in acute severe hypertension.
Topics: Administration, Sublingual; Child; Humans; Hypertension; Infant; Nifedipine | 1989 |
Cardiac and hemodynamic adjustments to rapid and sustained blood pressure reduction.
Topics: Blood Pressure; Delayed-Action Preparations; Female; Heart; Heart Ventricles; Hemodynamics; Humans; | 1989 |
Safety and efficacy of nifedipine 20 mg tablets in hypertension using electronic data collection in general practice.
Topics: Blood Pressure; Data Collection; Drug Evaluation; Family Practice; Female; Heart Rate; Humans; Hyper | 1989 |
[Adverse effects of nifedipine and treatment dropouts].
Topics: Humans; Hypertension; Nifedipine; Patient Compliance | 1989 |
Effects of calcium antagonists on hypertension and diastolic function.
Topics: Blood Pressure; Diastole; Diltiazem; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Con | 1989 |
Calcium channel blockers for tardive dyskinesia in geriatric psychiatric patients.
Topics: Age Factors; Aged; Aged, 80 and over; Dyskinesia, Drug-Induced; Female; Humans; Hypertension; Male; | 1989 |
[Acute natriuretic effect of nifedipine in elderly people with essential hypertension].
Topics: Aged; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nifedipine | 1989 |
Effect of long-term nifedipine treatment on body fluid composition in essential hypertension.
Topics: Adult; Blood Pressure; Body Fluids; Extracellular Space; Female; Humans; Hypertension; Kidney; Male; | 1989 |
[Nifedipine level in the blood and its immediate hypotensive effect after its sublingual administration to aged patients].
Topics: Administration, Sublingual; Aged; Antihypertensive Agents; Humans; Hypertension; Nifedipine | 1989 |
Effects of nisoldipine on sympathetic activity, the renin-angiotensin-aldosterone system, and water-sodium-calcium metabolism in patients with essential hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium; Calcium Channel Blockers; Creatinine; Female; Humans; Hyperten | 1989 |
Abnormal contractile response of aortas from spontaneously hypertensive rats to Ca2+ after depletion of Ca2+ in Ca2+-free medium.
Topics: Animals; Aorta; Calcium; Dose-Response Relationship, Drug; Hypertension; In Vitro Techniques; Male; | 1989 |
Intranasal administration of nifedipine for treatment of hypertension.
Topics: Administration, Intranasal; Child, Preschool; Humans; Hypertension; Male; Nifedipine | 1989 |
Acute reduction of blood pressure in asymptomatic patients with severe hypertension. An idea whose time has come--and gone.
Topics: Antihypertensive Agents; Blood Pressure; Chlorthalidone; Clonidine; Drug Administration Schedule; Hu | 1989 |
[Therapeutic effect of verapamil in hypertension: an analysis of 52 cases].
Topics: Adult; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Verapamil | 1989 |
Acute natriuretic effect of nifedipine in elderly males with essential hypertension.
Topics: Aged; Blood Pressure; Diet; Glomerular Filtration Rate; Humans; Hypertension; Kidney Tubules; Middle | 1989 |
Suppression of renin-angiotensin system in the heart of spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Chromatography, Liquid; Heart; Hypertension; Male; Muzolimine; Myo | 1987 |
New approaches for the treatment of hypertensive urgencies and emergencies.
Topics: Antihypertensive Agents; Captopril; Emergencies; Enalapril; Humans; Hypertension; Labetalol; Nifedip | 1988 |
Regulation of alpha 2-adrenoceptor density in normotensive and hypertensive man.
Topics: Adenylyl Cyclases; Blood Platelets; Clonidine; Furosemide; Humans; Hypertension; Male; Nifedipine; N | 1987 |
Enalapril & nifedipine in essential hypertension; synergism of the hypotensive effects in combination.
Topics: Aged; Blood Pressure; Blood Urea Nitrogen; Creatinine; Drug Synergism; Drug Therapy, Combination; En | 1988 |
Abnormal renal responses to calcium entry blockade in normotensive offspring of hypertensive parents.
Topics: Adult; Blood Pressure; Calcium Channels; Female; Glomerular Filtration Rate; Humans; Hypertension; K | 1988 |
Free intracellular calcium in essential hypertension. Effects of nifedipine and captopril.
Topics: Adult; Aged; Blood Platelets; Blood Pressure; Calcium; Captopril; Female; Humans; Hypertension; Male | 1985 |
The influence of nifedipine treatment on counter-regulatory mechanisms in essential hypertension.
Topics: Adult; Aged; Body Fluid Compartments; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; R | 1985 |
Misleading paper about misleading statistics.
Topics: Blood Pressure; Humans; Hypertension; Nifedipine; Propranolol; Statistics as Topic | 1985 |
Long term experience of felodipine in combination with beta-blockade and diuretics in refractory hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alkaline Phosphatase; Antihypertensive Agents; Aspartate A | 1985 |
Sublingual captopril versus nifedipine in hypertensive crises.
Topics: Captopril; Humans; Hypertension; Mouth Floor; Nifedipine; Proline | 1985 |
[Central and peripheral hemodynamics during combined treatment of arterial hypertension with calcium antagonist nifedipine and beta-adrenergic blockader talinolol].
Topics: Adrenergic beta-Antagonists; Adult; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; | 1985 |
[Therapy of the hypertensive crisis].
Topics: Administration, Oral; Adrenergic beta-Antagonists; Calcium Channel Blockers; Clonidine; Dihydralazin | 1985 |
Treatment of hypertension with calcium antagonists.
Topics: Adrenergic beta-Antagonists; Aged; Calcium Channel Blockers; Costs and Cost Analysis; Diuretics; Fem | 1985 |
[Depot nifedipine in the treatment of patients with essential and renal hypertension without renal insufficiency].
Topics: Adrenergic beta-Antagonists; Adult; Delayed-Action Preparations; Drug Administration Schedule; Drug | 1985 |
Acute effect of nifedipine on blood pressure and left ventricular ejection fraction in severely hypertensive outpatients: predictive effects of acute therapy and prolonged efficacy when added to existing therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Cardiomegaly; Drug Therapy, Combination; F | 1986 |
Comparison of calcium antagonists with other antihypertensive agents.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Humans; Hypertension | 1986 |
Paradoxical effect of sodium restriction on blood pressure in people on slow-channel calcium blocking drugs.
Topics: Blood Pressure; Diet, Sodium-Restricted; Humans; Hypertension; Nifedipine; Time Factors; Verapamil | 1986 |
Hemodynamic effects of nifedipine in hypertension in the presence of elevated angiotensin-II and beta-adrenergic blockade.
Topics: Adrenergic beta-Antagonists; Adult; Angiotensin II; Blood Pressure; Drug Therapy, Combination; Femal | 1986 |
[Use of nifedipine in patients with advanced arteriosclerotic cardiopathy].
Topics: Adrenergic beta-Antagonists; Aged; Arrhythmias, Cardiac; Cardiac Output, Low; Coronary Artery Diseas | 1986 |
Nifedipine substituted for minoxidil in the treatment of refractory hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Delayed-Action Preparations; Diuretics; Dr | 1987 |
Effect of calcium entry blockers on blood pressure and vasoconstrictor responses to alpha-1 adrenoceptor stimulation in conscious spontaneously hypertensive rats.
Topics: Administration, Oral; Adrenergic alpha-Agonists; Animals; Aorta, Thoracic; Binding, Competitive; Blo | 1987 |
Sublingual nifedipine in the treatment of hypertensive crisis associated with monoamine oxidase inhibitors.
Topics: Acute Disease; Administration, Sublingual; Emergencies; Humans; Hypertension; Nifedipine | 1989 |
Nifedipine and myoclonic disorders.
Topics: Aged; Female; Humans; Hypertension; Myoclonus; Nifedipine | 1989 |
Increased vasodilator responsiveness to BRL 34915 in spontaneously hypertensive versus normotensive rats: contrast with nifedipine.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Rela | 1989 |
How urgent is 'urgent' hypertension?
Topics: Clonidine; Emergencies; Hospitalization; Humans; Hypertension; Nifedipine | 1989 |
Endothelium-mediated spontaneous response in aortic rings of deoxycorticosterone acetate-hypertensive rats.
Topics: Animals; Aorta, Thoracic; Calcium Chloride; Culture Techniques; Desoxycorticosterone; Dose-Response | 1989 |
Use of nifedipine as monotherapy in the management of hypertension.
Topics: Adult; Blood Pressure; Cardiomegaly; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Ni | 1985 |
[Nitrendipine, a new calcium antagonist, in the therapy of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hypertension; Male; | 1985 |
Hemodynamic effects of calcium entry-blocking agents in normal and hypertensive rats and man.
Topics: Animals; Calcium Channel Blockers; Diltiazem; Female; Hemodynamics; Humans; Hypertension; Male; Midd | 1985 |
Nitrendipine, a calcium-entry blocker. Renal and humoral effects in human arterial hypertension.
Topics: Adult; Aged; Aldosterone; Blood Volume; Body Fluids; Calcium Channel Blockers; Catecholamines; Elect | 1986 |
[Calcium antagonists in the therapy of essential arterial hypertension. Analysis of the results obtained with 3 drugs].
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1985 |
[Progression and regression of heart hypertrophy in arterial hypertension: pathophysiology and clinical aspects].
Topics: Blood Pressure; Cardiac Volume; Cardiomegaly; Cardiomyopathy, Hypertrophic; Clonidine; Coronary Circ | 1985 |
[Stress pulsed Doppler echocardiography in the evaluation of diastolic left ventricular function].
Topics: Cardiomegaly; Cardiomyopathy, Hypertrophic; Coronary Disease; Diastole; Echocardiography; Heart Vent | 1985 |
[Medium-term use of nitrendipine in the treatment of essential arterial hypertension].
Topics: Adult; Antihypertensive Agents; Drug Evaluation; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1985 |
Haemodynamic effects of vasodilating drugs on the common carotid and brachial circulations of patients with essential hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Brachial Artery; Captopril; Carotid Arteries | 1986 |
Binding of [3H]nitrendipine to cardiac and cerebral membranes from normotensive and renal, deoxycorticosterone/NaCl and spontaneously hypertensive rats.
Topics: Animals; Binding Sites; Brain; Desoxycorticosterone; Hypertension; Hypertension, Renal; In Vitro Tec | 1986 |
Increased plasma atrial natriuretic polypeptide in patients with severe essential hypertension and its decline with antihypertensive therapy with nifedipine.
Topics: Adult; Atrial Natriuretic Factor; Emergencies; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1986 |
[Therapeutic effect of nitrendipine in the treatment of systemic hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; N | 1986 |
[Nitrendipine in the treatment of elderly hypertensive patients. Study of observations on effectiveness and tolerance].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nife | 1986 |
[Hypertensive attacks in pheochromocytoma. Value of nifedipine by the sublingual route].
Topics: Adrenal Gland Neoplasms; Adult; Humans; Hypertension; Male; Nifedipine; Pheochromocytoma | 1986 |
[Essential arterial hypertension: main vasodilator effect of nifedipine].
Topics: Animals; Aorta; Blood Circulation; Blood Pressure; Female; Heart Rate; Hemodynamics; Humans; Hyperte | 1986 |
[Effect of nifedipine on blood pressure, calmodulin and cyclic nucleotides in plasma and aorta from spontaneously hypertensive rats].
Topics: Animals; Aorta; Blood Pressure; Calmodulin; DNA; Hypertension; Male; Nifedipine; Nucleotides, Cyclic | 1987 |
Role of nisoldipine on blood pressure, cardiac hypertrophy, and atrial natriuretic peptides in spontaneously hypertensive rats.
Topics: Animals; Atrial Natriuretic Factor; Blood Pressure; Cardiomegaly; Hypertension; Male; Nifedipine; Ni | 1987 |
Amlodipine therapy corrects renal abnormalities encountered in the hypertensive state.
Topics: Adult; Aged; Amlodipine; Blood Pressure; Body Fluids; Calcium Channel Blockers; Drug Evaluation; Glo | 1987 |
Cardiac hypertrophy in hypertension. Repolarization abnormalities elicited by rapid lowering of pressure.
Topics: Adult; Blood Pressure; Cardiomegaly; Electrocardiography; Female; Heart Rate; Humans; Hypertension; | 1988 |
Long-term effect of antihypertensive therapy on left ventricular hypertrophy.
Topics: Adult; Antihypertensive Agents; Atenolol; Cardiomegaly; Drug Therapy, Combination; Echocardiography; | 1987 |
A study of the action of amlodipine on adrenergically regulated sodium handling by the kidney in normotensive and hypertensive rats.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Hypertension; Kidney; Kidney Concentrating Ability; K | 1988 |
A study of the renal actions of amlodipine in the normotensive and spontaneously hypertensive rat.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Hypertension; Kidney Tubules; Kidney Tubules, Proxima | 1988 |
[Long-term treatment with nifedipine does not alter carbohydrate tolerance in normal subjects and does not worsen metabolic control in diabetics].
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Huma | 1987 |
[Hypertensive emergencies treated with nifedipine drops].
Topics: Administration, Oral; Aged; Aged, 80 and over; Drug Evaluation; Emergencies; Female; Humans; Hyperte | 1987 |
Electrocardiographic alterations suggestive of myocardial injury elicited by rapid pressure lowering in hypertension.
Topics: Adult; Blood Pressure; Cardiomegaly; Coronary Circulation; Electrocardiography; Ferricyanides; Heart | 1988 |
Amlodipine and captopril in moderate-severe essential hypertension.
Topics: Adolescent; Adult; Aged; Amlodipine; Calcium Channel Blockers; Captopril; Double-Blind Method; Drug | 1988 |
The role of endogenous inhibition of Na-K-ATPase in human hypertension--sodium pump activity as a determinant of peripheral vascular resistance.
Topics: Animals; ATPase Inhibitory Protein; Calcium Channel Blockers; Heart; Hemodynamics; Humans; Hyperaldo | 1985 |
Adrenergic activity and left ventricular function during treatment of essential hypertension with calcium antagonists.
Topics: Adult; Blood Pressure; Epinephrine; Female; Heart; Heart Rate; Humans; Hypertension; Isoproterenol; | 1986 |
[Calcium channel blockers and angiotensin converting enzyme inhibitors in the treatment of high blood pressure].
Topics: Calcium Channel Blockers; Captopril; Drug Interactions; Enalapril; Humans; Hypertension; Nifedipine; | 1986 |
Effect of nifedipine in hypertension not controlled by converting enzyme inhibitor and diuretic.
Topics: Adult; Aldosterone; Blood Pressure; Captopril; Drug Therapy, Combination; Enalapril; Female; Furosem | 1986 |
Acute hypotensive effect of calcium antagonists and endogenous digitalis-like immunoreactivity in human essential hypertension.
Topics: Adult; Aged; Blood Pressure; Blood Proteins; Calcium Channel Blockers; Cardenolides; Digoxin; Humans | 1986 |
Antihypertensive effects of the new calcium antagonist benidipine hydrochloride in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemical Phenomena; Chem | 1988 |
Influence of glyceryl trinitrate and nifedipine on coronary sinus blood flow and global myocardial metabolism during coronary artery operation.
Topics: Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Heart; Hemodynamics; Humans; Hypertensi | 1986 |
[Effects of nifedipine on carotid blood flow and baroreflex response in essential arterial hypertension. Preliminary results].
Topics: Aged; Blood Flow Velocity; Blood Pressure; Carotid Arteries; Female; Heart Rate; Humans; Hypertensio | 1986 |
Long-term effects of nifedipine on plasma levels of 25 hydroxyvitamin D and 1,25 dihydroxyvitamin D in hypertensive hemodialyzed patients.
Topics: Calcifediol; Calcitriol; Humans; Hypertension; Long-Term Care; Nifedipine; Renal Dialysis | 1986 |
[Problems in acute therapy of coronary heart disease using drugs that reduce preload and afterload].
Topics: Coronary Disease; Heart Failure; Hemodynamics; Humans; Hypertension; Molsidomine; Nifedipine; Nitrog | 1987 |
Does nifedipine ameliorate cyclosporin A nephrotoxicity?
Topics: Adult; Cyclosporins; Humans; Hypertension; Kidney; Kidney Diseases; Kidney Transplantation; Middle A | 1987 |
Preeclampsia: platelets and antiplatelet therapy.
Topics: Aspirin; Blood Coagulation; Blood Platelets; Diagnosis, Differential; Female; Fetus; Humans; Hyperte | 1988 |
The control of hypertension and its effect on renal function in rat remnant kidney.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Creatinine; Dietary Proteins; Dihydralazine; Fema | 1988 |
Short- and long-term efficacy of nifedipine in hypertensive patients with impaired renal function, with special reference to influencing factors.
Topics: Adult; Aldosterone; Blood Pressure; Blood Urea Nitrogen; Creatinine; Female; Humans; Hypertension; K | 1987 |
[Continuous blood pressure monitoring in cataract operations under local anesthesia].
Topics: Aged; Aged, 80 and over; Anesthesia, Local; Antihypertensive Agents; Blood Pressure; Blood Pressure | 1988 |
Diuretics and calcium antagonists in hypertension.
Topics: Bendroflumethiazide; Diuretics; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension | 1988 |
[Treatment of human arterial hypertension. Role of calcium channel inhibitors].
Topics: Antihypertensive Agents; Calcium Channel Blockers; Drug Therapy, Combination; Emergencies; Humans; H | 1985 |
Nifedipine in severely hypertensive patients with congestive heart failure and preserved ventricular systolic function.
Topics: Aged; Cardiomegaly; Electrocardiography; Female; Heart Failure; Heart Ventricles; Humans; Hypertensi | 1985 |
Cardiac hypertrophy and arterial distensibility in essential hypertension.
Topics: Adult; Aged; Arteries; Blood Flow Velocity; Cardiomegaly; Humans; Hypertension; Middle Aged; Nifedip | 1985 |
The influence of monotherapy with oxprenolol and nitrendipine on ambulatory blood pressure in hypertensives.
Topics: Adult; Ambulatory Care; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Human | 1985 |
Effects of chronic nitrendipine on casual (office) and 24-hour ambulatory blood pressure.
Topics: Adult; Aged; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1985 |
[Nitrendipine, a new calcium antagonist, as basis therapy in essential hypertension].
Topics: Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Humans; Hypertension; Mi | 1985 |
Age related antihypertensive effect of nitrendipine, a new calcium entry blocking agent.
Topics: Adult; Age Factors; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Middle Aged; Nif | 1985 |
[Treatment of hypertension during acute myocardial infarct and unstable angina].
Topics: Aged; Angina Pectoris; Angina, Unstable; Female; Humans; Hypertension; Male; Myocardial Infarction; | 1988 |
Nifedipine and surgical removal of phaeochromocytoma.
Topics: Adrenal Gland Neoplasms; Adult; Arrhythmias, Cardiac; Female; Humans; Hypertension; Intraoperative C | 1988 |
The inhibitory effects of nifedipine and fentanyl on circulatory response during laryngoscopy and intubation in patients pretreated with neosynephrine eye drops for mydriasis.
Topics: Female; Fentanyl; Hemodynamics; Humans; Hypertension; Intubation, Intratracheal; Laryngoscopy; Male; | 1988 |
[Treatment of hypertensive emergencies and crisis with sublingual nifedipine].
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Blood Pressure; Drug Evaluation; Emergen | 1988 |
[Renal hemodynamics in hypertensive nephritis: the effect of nifedipine].
Topics: Adult; Female; Glomerulonephritis; Hemodynamics; Humans; Hypertension; Male; Nifedipine; Renal Circu | 1988 |
Nifedipine does not adversely affect uteroplacental blood flow in the hypertensive term-pregnant rat.
Topics: Animals; Female; Hemodynamics; Hypertension; Nifedipine; Placenta; Pregnancy; Pregnancy Complication | 1988 |
Comparison of the cardiovascular effects of trans-diclofurime with different types of calcium antagonists in conscious spontaneously hypertensive rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Heart Rate; Hemodynamics; Hypertension | 1988 |
Lithium clearance and renal tubular sodium handling during acute and long-term nifedipine treatment in essential hypertension.
Topics: Absorption; Adult; Aged; Drug Administration Schedule; Female; Humans; Hypertension; Kidney Tubules; | 1988 |
Treatment of hypertensive emergencies with nifedipine.
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Blood Pressure; Emergencies; Heart Rate; | 1988 |
Effects of nilvadipine on the cardiovascular system in experimental animals.
Topics: Animals; Calcium; Calcium Channel Blockers; Coronary Disease; Coronary Vessels; Dogs; Female; Guinea | 1988 |
Antihypertensive effects of intravenous administration of benidipine hydrochloride and some other calcium antagonists in conscious, spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dose-Response | 1988 |
Treatment of hypertensive crisis in children with nifedipine.
Topics: Administration, Sublingual; Adolescent; Child; Female; Humans; Hypertension; Infant; Male; Nifedipin | 1988 |
Effects of verapamil and nifedipine on systemic hemodynamics in spontaneously hypertensive rats.
Topics: Animals; Consciousness; Dose-Response Relationship, Drug; Hemodynamics; Hypertension; Male; Nifedipi | 1988 |
[A comparison of the effects of nifedipine and nifedipine retard on blood pressure reduction before and after treadmill exercise].
Topics: Adult; Blood Pressure; Delayed-Action Preparations; Exercise Test; Female; Heart Rate; Humans; Hyper | 1988 |
The effect of salt loading on cellular Ca2+ in patients with essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Diet, Sodium-Restricted; Extracellular Space; Female; Humans; Hypert | 1988 |
[Open study to evaluate the efficacy and tolerance of prolonged-action nifedipine in the treatment of mild to moderate essential arterial hypertension].
Topics: Delayed-Action Preparations; Drug Evaluation; Humans; Hypertension; Nifedipine | 1988 |
[The relation of hypotensive effects of nifedipine and clonidine and changes in platelet-free calcium and serum-free calcium in essential hypertension].
Topics: Adult; Aged; Blood Platelets; Calcium; Clonidine; Female; Humans; Hypertension; Male; Middle Aged; N | 1988 |
Subcutaneous administration of nifedipine.
Topics: Aged; Emergencies; Female; Humans; Hypertension; Injections, Subcutaneous; Nifedipine | 1988 |
Acute drug interaction between indomethacin and nifedipine in hypertensive patients.
Topics: Drug Interactions; Female; Humans; Hypertension; Indomethacin; Male; Middle Aged; Nifedipine | 1988 |
The haemodynamic effects of intravenous nifedipine in normotensive and hypertensive subjects.
Topics: Adult; Female; Hemodynamics; Humans; Hypertension; Infusions, Intravenous; Male; Middle Aged; Nifedi | 1988 |
Relationship of cellular calcium to salt sensitivity in patients with essential hypertension.
Topics: Calcium; Humans; Hypertension; Lymphocytes; Middle Aged; Nifedipine; Sodium, Dietary | 1988 |
Platelets as a model for studying the action of antihypertensive drugs.
Topics: Adult; Aminoquinolines; Antihypertensive Agents; Blood Platelets; Calcium; Drug Therapy, Combination | 1988 |
Effects of nifedipine on blood pressure and heart rate in conscious neurogenic hypertensive rats.
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nifedipine; Rat | 1988 |
[Heart-filling pressure in patients with hypertension treated by nifedipine].
Topics: Adult; Blood Pressure; Chronic Disease; Diastole; Drug Evaluation; Heart; Humans; Hypertension; Male | 1988 |
[A case of acute respiratory failure precipitated by long-acting nifedipine].
Topics: Acute Disease; Aged; Delayed-Action Preparations; Drug Hypersensitivity; Humans; Hypertension; Male; | 1988 |
Safe use of clonidine, nifedipine and vitamin K in hepatic porphyria.
Topics: Adult; Clonidine; Humans; Hypertension; Liver Diseases; Male; Nifedipine; Porphyrias; Vitamin K | 1988 |
[Left and right ventricular diastolic properties in essential hypertension during cold pressor test: noninvasive assessment by pulsed Doppler echocardiography].
Topics: Adult; Blood Flow Velocity; Blood Pressure; Cold Temperature; Diastole; Echocardiography, Doppler; F | 1988 |
[Diastolic left ventricular volume flow in patients with arterial hypertension before and following acute antihypertensive medication].
Topics: Administration, Oral; Adult; Aged; Blood Flow Velocity; Blood Pressure; Cardiac Output; Drug Therapy | 1988 |
Effect of nifedipine and mefruside on renal reserve in hypertensive patients.
Topics: Adult; Dietary Proteins; Diuretics; Glomerular Filtration Rate; Humans; Hypertension; Mefruside; Mid | 1988 |
Sublingual nifedipine in acute severe hypertension.
Topics: Acute Disease; Administration, Sublingual; Adolescent; Child; Humans; Hypertension; Nifedipine | 1988 |
[Extracardiovascular effects of nifedipine in the treatment of hypertensive patients: glucose tolerance and behavior of immunoreactive insulin].
Topics: Adult; Blood Glucose; C-Peptide; Female; Glucose Tolerance Test; Humans; Hypertension; Insulin; Male | 1988 |
[Sublingual nifedipine or captopril as treatment of hypertensive crisis].
Topics: Administration, Sublingual; Adult; Aged; Aged, 80 and over; Captopril; Female; Humans; Hypertension; | 1988 |
Antihypertensive effects of nisoldipine and reference drugs in certain types of hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Desoxycorticosterone; Hypertension; Hypertension, | 1987 |
Effect of nifedipine on glucose tolerance, serum insulin, and serum fructosamine in diabetic and nondiabetic patients.
Topics: Blood Glucose; Diabetes Mellitus, Type 2; Female; Fructosamine; Glucose Tolerance Test; Hexosamines; | 1987 |
[Nifedipine-captopril combination in the treatment of refractory arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1986 |
[Hypertensive crisis: comparative study of oral captopril, sublingual captopril and sublingual nifedipine].
Topics: Administration, Oral; Adult; Blood Pressure; Captopril; Drug Evaluation; Female; Humans; Hypertensio | 1987 |
[Captopril and nifedipine: comparative study of the immediate arterial pressure response in various grades of hypertension].
Topics: Adult; Blood Pressure; Captopril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renin | 1987 |
Effect of the calcium antagonist nilvadipine on haemodynamics at rest and during cold stimulation in essential hypertension.
Topics: Adult; Aged; Calcium Channel Blockers; Catecholamines; Cold Temperature; Female; Hemodynamics; Human | 1987 |
[Combination of angiotensin-converting enzyme inhibitors and calcium antagonists: an effective therapeutic regimen in hypertensive crisis].
Topics: Blood Pressure; Captopril; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; | 1987 |
Blood pressure response to a calcium entry blocker in normotensive subjects with or without a family history of hypertension.
Topics: Adult; Blood Pressure; Epinephrine; Heart Rate; Humans; Hypertension; Male; Nifedipine; Norepinephri | 1987 |
The pathophysiological role of blood ionized calcium in essential hypertension.
Topics: Adult; Blood Pressure; Calcium; Humans; Hypertension; Middle Aged; Nifedipine; Norepinephrine; Plasm | 1987 |
Calcium antagonists and responsiveness of the adrenal glands to aldosterone-releasing stimuli in hypertensive patients.
Topics: Adrenal Glands; Adult; Aged; Aldosterone; Angiotensin II; Calcium Channel Blockers; Drug Evaluation; | 1987 |
Effect of water immersion on plasma renin activity, aldosteronaemia and vasopressinaemia in hypertensive patients before and during the treatment with nifedipine.
Topics: Adult; Female; Humans; Hypertension; Hypoaldosteronism; Immersion; Male; Nifedipine; Renin | 1986 |
Chronic effects of nitrendipine on renal hemodynamics and tubular transport.
Topics: Adult; Blood Pressure; Diuresis; Glomerular Filtration Rate; Humans; Hypertension; Kidney Tubules, P | 1988 |
Functional versus structural changes of forearm vascular resistance in hypertension.
Topics: Adult; Arteries; Blood Pressure; Constriction; Forearm; Humans; Hyperemia; Hypertension; Male; Middl | 1988 |
[Effect of an acute pharmacological test and a course of treatment with nifedipine on cerebral hemodynamic indices and information processing efficiency in hypertension patients].
Topics: Adolescent; Adult; Cerebrovascular Circulation; Coronary Disease; Efficiency; Female; Hemodynamics; | 1988 |
[Hypotensive effect of nifedipine in hypertension patients with different functional activity of the sympathetic-adrenal system].
Topics: Adrenal Glands; Adult; Blood Pressure; Drug Evaluation; Humans; Hypertension; Male; Nifedipine; Symp | 1988 |
[Effect of nifedipine on left ventricular function in arterial hypertension studied by Doppler echocardiography].
Topics: Adult; Echocardiography; Heart; Heart Ventricles; Hemodynamics; Humans; Hypertension; Male; Nifedipi | 1988 |
Effect of sublingual or oral nifedipine in the treatment of hypertension.
Topics: Administration, Oral; Administration, Sublingual; Adolescent; Child; Child, Preschool; Humans; Hyper | 1988 |
Effect of nifedipine on renal function in patients with essential hypertension.
Topics: Adult; Aged; Blood Pressure; Creatinine; Female; Glomerular Filtration Rate; Humans; Hypertension; K | 1988 |
Studies on the anti-vasoconstrictor activity of BRL 34915 in spontaneously hypertensive rats; a comparison with nifedipine.
Topics: Angiotensin II; Animals; Benzopyrans; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; | 1988 |
Fixed combination of atenolol and nifedipine in cardiovascular medicine. Partial proceedings of a workshop. London, 21 January, 1987.
Topics: Atenolol; Coronary Disease; Drug Therapy, Combination; Humans; Hypertension; Nifedipine | 1988 |
Treatment of hypertension with a combination of nifedipine and atenolol compared with atenolol alone. Preliminary report.
Topics: Adolescent; Adult; Aged; Atenolol; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hypert | 1988 |
Tolerability, safety and dosage of a fixed combination of sustained release nifedipine plus atenolol.
Topics: Adult; Aged; Atenolol; Blood Pressure; Delayed-Action Preparations; Drug Therapy, Combination; Drug | 1988 |
[Effect of corinfar on indicators of cerebral circulation in patients with hypertension].
Topics: Adult; Aged; Cerebrovascular Circulation; Female; Humans; Hypertension; Male; Middle Aged; Nifedipin | 1988 |
[Corinfar in the treatment of patients in the initial stages of arterial hypertension].
Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Female; Humans; Hypertension; Male; Nife | 1988 |
Nisoldipine: a replacement therapy for nifedipine in the treatment of severe hypertension.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Ag | 1988 |
A comparative study of the acute antihypertensive effect of Adalat capsules and Corinfar dragées, two different nifedipine preparations.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Capsules; Female; Heart Rate; Humans; Hypertensio | 1988 |
Role of cellular calcium in salt sensitivity of patients with essential hypertension.
Topics: Adult; Calcium; Female; Hemodynamics; Humans; Hypertension; Lymphocytes; Male; Middle Aged; Nifedipi | 1988 |
Effects of nifedipine on intracranial pressure in neurosurgical patients with arterial hypertension.
Topics: Adult; Aged; Brain Diseases; Female; Humans; Hypertension; Intracranial Pressure; Male; Middle Aged; | 1988 |
[Use of calcium antagonists (sublingually) in the treatment of hypertensive crises].
Topics: Administration, Sublingual; Aged; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; | 1988 |
Acute effects of nifedipine on renal electrolyte excretion in normal and hypertensive subjects.
Topics: Calcium; Humans; Hypertension; Kidney; Magnesium; Natriuresis; Nifedipine; Potassium; Sodium; Water | 1988 |
Treatment of hypertensive crisis with intranasal nifedipine.
Topics: Acute Disease; Administration, Intranasal; Adult; Child; Child, Preschool; Humans; Hypertension; Mal | 1988 |
Magnesium plus nifedipine: potentiation of hypotensive effect in preeclampsia?
Topics: Adult; Drug Synergism; Female; Humans; Hypertension; Magnesium Sulfate; Methyldopa; Nifedipine; Pre- | 1988 |
Increased current delivery and sperm collection using nifedipine during electroejaculation in men with high spinal cord injuries.
Topics: Adult; Blood Pressure; Ejaculation; Electric Stimulation; Humans; Hypertension; Infertility, Male; M | 1988 |
Nifedipine, its action on the cationic concentrations in heart, vessels, skeletal muscle and blood in tissues of normotensive and spontaneously hypertensive rats (SHR).
Topics: Animals; Blood Vessels; Body Water; Cations; Heart; Hypertension; Male; Muscles; Myocardium; Nifedip | 1988 |
[Effects of calcium antagonists on hemodynamic responses to upright posture and isometric exercise in elderly hypertensives].
Topics: Aged; Aged, 80 and over; Calcium Channel Blockers; Female; Hemodynamics; Humans; Hypertension; Isome | 1988 |
[Control of hypertensive crises with cordipin].
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1987 |
Nifedipine as a second line antihypertensive drug in pregnancy.
Topics: Adult; Atenolol; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertensio | 1987 |
Comment: Nifedipine in hypertensive emergencies.
Topics: Administration, Oral; Administration, Sublingual; Emergencies; Humans; Hypertension; Nifedipine | 1987 |
Nifedipine hepatitis.
Topics: Aged; Aged, 80 and over; Angina Pectoris; Biopsy; Chemical and Drug Induced Liver Injury; Female; Hu | 1987 |
The effect of antihypertensive treatment on the circulating hypertensive factor in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Cross Circulation; Furosemide; Hypertension; Male; Methyldopa; Nif | 1987 |
Improved myocardial capillarisation in spontaneously hypertensive rats treated with nifedipine.
Topics: Animals; Body Weight; Capillaries; Coronary Circulation; Hypertension; Male; Microcirculation; Myoca | 1987 |
Nifedipine, sodium intake, diuretics, and sodium balance.
Topics: Bendroflumethiazide; Blood Pressure; Drug Interactions; Drug Therapy, Combination; Female; Humans; H | 1987 |
Glycaemic control and exercise tolerance in hypertensive insulin-treated diabetes during nifedipine therapy.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 1; Exercise Test; Female; Humans; Hypertension; Male; | 1987 |
Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dr | 1987 |
Efficacy of sublingual nifedipine in the relief of immediate post-operative hypertension.
Topics: Administration, Sublingual; Adult; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Post | 1987 |
[Aggravation of chronic renal insufficiency by nifedipine].
Topics: Creatinine; Female; Humans; Hypertension; Kidney Failure, Chronic; Middle Aged; Nifedipine | 1987 |
[Nifedipine in the emergency and chronic treatment of arterial hypertension].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Em | 1987 |
[Clinical pharmacokinetics of the nifedipine preparations Adalat, Corinfar and Cordafen-Polfa].
Topics: Antihypertensive Agents; Biological Availability; Capsules; Humans; Hypertension; Nifedipine; Tablet | 1987 |
The effect of nifedipine on plasma lipids in patients with essential hypertension.
Topics: Adult; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Female; Humans; Hypertens | 1986 |
Calcium channel antagonists--cardiovascular therapy for the eighties?
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; | 1986 |
Calcium channel blockade with nifedipine reduces the systemic and the pulmonary vascular reactivity to adrenergic activation in hypertension.
Topics: Adult; Calcium Channel Blockers; Epinephrine; Humans; Hypertension; Male; Nifedipine; Norepinephrine | 1986 |
Acute and chronic hemodynamic effects of nisoldipine in essential hypertension at rest and during exercise.
Topics: Female; Hemodynamics; Humans; Hypertension; Male; Nifedipine; Nisoldipine; Physical Exertion | 1986 |
Long-term antihypertensive and metabolic effects of nifedipine slow-release tablets in elderly hypertensives.
Topics: Aged; Aged, 80 and over; Blood Pressure; Calcium; Creatinine; Delayed-Action Preparations; Female; H | 1986 |
Nifedipine, diuretics and sodium balance.
Topics: Blood Pressure; Diuretics; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Human | 1987 |
Slow-release nifedipine: effect on the circadian rhythm of blood pressure in essential hypertension.
Topics: Administration, Oral; Aged; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Female; H | 1987 |
Nifedipine in the treatment of hypertension in systemic lupus erythematosus.
Topics: Antibodies; Antibodies, Antinuclear; Blood Pressure; Complement System Proteins; DNA; Drug Evaluatio | 1987 |
Effects of calcium entry blockers on blood pressure and heart rate in neurogenic hypertensive dogs.
Topics: Animals; Bepridil; Blood Pressure; Calcium Channel Blockers; Denervation; Diltiazem; Dogs; Female; H | 1987 |
Nifedipine: a calcium channel blocking drug.
Topics: Angina Pectoris; Humans; Hypertension; Nifedipine; Raynaud Disease | 1987 |
[Essential arterial hypertension: therapeutic experience with "nifedipine A. R."].
Topics: Adult; Aged; Delayed-Action Preparations; Humans; Hypertension; Middle Aged; Nifedipine | 1987 |
Effects of combination therapy with captopril and nifedipine in severe or resistant hypertension.
Topics: Adult; Aged; Blood Pressure; Captopril; Drug Evaluation; Drug Therapy, Combination; Edema; Female; H | 1986 |
Similarities and differences in the antihypertensive effect of two calcium antagonist drugs, verapamil and nifedipine.
Topics: Adult; Blood Pressure; Echocardiography; Epinephrine; Female; Heart Rate; Humans; Hypertension; Male | 1986 |
[Effect of nifedipine pretreatment on SNP doses and overshoot hypertension after discontinuation of SNP in SNP-induced hypotension anesthesia].
Topics: Adjuvants, Anesthesia; Adult; Blood Pressure; Cyanides; Female; Ferricyanides; Humans; Hypertension; | 1986 |
Antihypertensive effect of a new calcium channel blocker, FK 235, in essential hypertension.
Topics: Adult; Aged; Aldosterone; Antihypertensive Agents; Calcium Channel Blockers; Female; Humans; Hyperte | 1986 |
Lack of effect of nifedipine on counterregulatory mechanisms in essential hypertension.
Topics: Adult; Aged; Aldosterone; Angiotensin II; Catecholamines; Female; Glomerular Filtration Rate; Humans | 1986 |
The effect of 8 weeks treatment with the calcium antagonist felodipine on blood pressure, heart rate, working capacity, plasma renin activity, plasma angiotensin II, urinary catecholamines and aldosterone in patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Antihypertensive Agents; Catecholamines; Felodipine; Heart Rate; | 1986 |
Management of urgent hypertension: a comparison of oral treatment regimens in the emergency department.
Topics: Administration, Oral; Antihypertensive Agents; Captopril; Clonidine; Drug Administration Schedule; E | 1986 |
Short-term efficacy of nifedipine in essential and renovascular hypertension.
Topics: Adult; Aged; Blood Pressure; Female; Humans; Hypertension; Hypertension, Renovascular; Male; Middle | 1986 |
Combined nifedipine and captopril treatment in moderately severe primary hypertension.
Topics: Aged; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Midd | 1986 |
Calcium antagonists: interactions in hypertension.
Topics: Adult; Blood Pressure; Clonidine; Drug Interactions; Female; Humans; Hypertension; Indomethacin; Mal | 1986 |
[Plasma noradrenaline level after oral administration of captopril].
Topics: Administration, Oral; Adult; Blood Pressure; Captopril; Female; Heart Rate; Humans; Hypertension; Ma | 1987 |
[Transcranial Doppler study of sylvian vascular reactivity as affected by a calcium inhibitor. Preliminary results apropos of 28 cases].
Topics: Adult; Aged; Calcium Channel Blockers; Cerebral Arteries; Cerebrovascular Circulation; Female; Human | 1987 |
Use of nifedipine as the drug of third choice in management of hypertension.
Topics: Adult; Aged; Atenolol; Benzothiadiazines; Blood Pressure; Diuretics; Humans; Hypertension; Middle Ag | 1986 |
[Plasma levels of nifedipine (Adalat Retard) in aged hypertensive patients].
Topics: Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1987 |
[Effect of hypotensive therapy and exercise schedules on the bicycle ergometry indices of essential hypertension patients].
Topics: Adult; Antihypertensive Agents; Benzothiadiazines; Blood Pressure; Diuretics; Drug Therapy, Combinat | 1987 |
[Pharmacodynamic interaction of clonidine and nifedipine].
Topics: Adult; Aged; Blood Pressure; Cardiac Output; Clonidine; Diastole; Drug Interactions; Female; Heart R | 1987 |
[The vasodilator minoxidil in the treatment of hypertension].
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Mi | 1987 |
New formulation of Adalat (nifedipine) tablets.
Topics: Humans; Hypertension; Male; Medication Errors; Middle Aged; Nifedipine | 1987 |
Dissociation between calcium influx blockage and smooth muscle relaxation by nifedipine in spontaneously hypertensive rats.
Topics: Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Hypertension; Male; Mu | 1987 |
Treatment of MAOI hypertensive crisis with sublingual nifedipine.
Topics: Acute Disease; Adult; Depressive Disorder; Female; Humans; Hypertension; Middle Aged; Monoamine Oxid | 1987 |
[Nifedipine in the treatment of arterial hypertension].
Topics: Adult; Aged; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertensio | 1987 |
[Treatment of hypertensive crises with nifedipine (Adalat) in patients at risk of infarct during interventions on the extracranial cerebral vessels].
Topics: Adult; Aged; Aged, 80 and over; Cardiac Output, Low; Carotid Artery Diseases; Carotid Artery, Intern | 1987 |
Nifedipine-associated myocardial ischemia or infarction in the treatment of hypertensive urgencies.
Topics: Administration, Oral; Coronary Disease; Electrocardiography; Emergencies; Female; Humans; Hypertensi | 1987 |
Comparative antihypertensive effects of nifedipine and nicardipine in adult and aged spontaneously hypertensive rats.
Topics: Aging; Animals; Antihypertensive Agents; Blood Pressure; Heart Rate; Hypertension; Nicardipine; Nife | 1987 |
Sublingual nifedipine in severe hypertension with advanced renal failure.
Topics: Administration, Oral; Adult; Aged; Female; Humans; Hypertension; Kidney Failure, Chronic; Male; Midd | 1987 |
Ca2+ influx in spontaneously hypertensive rats is sensitive to calcium antagonists.
Topics: Animals; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Hypertension; In Vitro Techniques; Male | 1987 |
Calcium, the renin-aldosterone system, and the hypotensive response to nifedipine.
Topics: Aldosterone; Blood Pressure; Calcium; Humans; Hypertension; Nifedipine; Renin-Angiotensin System | 1987 |
[Treatment of arterial hypertension with corinfar].
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hype | 1987 |
Rupture of a cerebral aneurysm associated with nifedipine treatment.
Topics: Adult; Female; Humans; Hypertension; Intracranial Aneurysm; Nifedipine; Rupture, Spontaneous; Subara | 1986 |
Symptomatic hypotension induced by nifedipine.
Topics: Drug Administration Schedule; Emergencies; Humans; Hypertension; Hypotension; Nifedipine | 1987 |
Hypotensive and natriuretic effects of nifedipine in essential hypertension. Role of renal kallikrein-kinin-prostaglandin and renin-angiotensin-aldosterone systems.
Topics: Adult; Blood Pressure; Female; Humans; Hypertension; Kallikreins; Male; Middle Aged; Natriuresis; Ni | 1986 |
Influence of the sympathetic nervous system and vasopressin on the blood pressure lowering effect of nifedipine in deoxycorticosterone acetate-salt hypertensive rats.
Topics: Analysis of Variance; Animals; Blood Pressure; Desoxycorticosterone; Heart Rate; Hypertension; Male; | 1987 |
Sublingual nifedipine therapy in accelerated hypertension and acute cardiac ischaemia.
Topics: Administration, Sublingual; Coronary Disease; Humans; Hypertension; Nifedipine | 1987 |
[Effect of the calcium antagonist nifedipine on blood pressure and its circadian rhythm in patients with hypertension].
Topics: Adult; Aged; Aged, 80 and over; Blood Pressure; Circadian Rhythm; Humans; Hypertension; Middle Aged; | 1987 |
Effects of diltiazem alone and combined with mefruside on cardiovascular response at rest and during exercise, carbohydrate metabolism and serum lipoproteins in patients with systemic hypertension.
Topics: Adult; Blood Pressure; Carbohydrate Metabolism; Diltiazem; Diuretics; Drug Therapy, Combination; Fem | 1987 |
Photoplethysmographic assessment of digital arterial compliance in the diagnosis and treatment of hypertension.
Topics: Adult; Arteries; Compliance; Female; Fingers; Hemodynamics; Humans; Hypertension; Light; Male; Middl | 1987 |
[The combination of nifedipine and a low sodium diet with potassium supplement in the therapy of essential arterial hypertension].
Topics: Combined Modality Therapy; Delayed-Action Preparations; Diet, Sodium-Restricted; Female; Humans; Hyp | 1987 |
Clinical efficacy and bioavailability of a sustained release nifedipine formulation.
Topics: Adult; Aged; Aged, 80 and over; Angina Pectoris; Biological Availability; Delayed-Action Preparation | 1987 |
The antihypertensive efficacy of nifedipine alone and in combination in general practice.
Topics: Adult; Aged; Aging; Blood Pressure; Drug Therapy, Combination; Family Practice; Female; Follow-Up St | 1987 |
Lack of a relationship between age and the antihypertensive effect of nifedipine tablets in patients up to 70 years of age.
Topics: Age Factors; Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1987 |
[Anti-hypertensive activity of P0285 and nifedipine in conscious normotensive rats and in rats with spontaneous, renal and desoxycorticosterone acetate-induced hypertension].
Topics: Animals; Calcium Channel Blockers; Desoxycorticosterone; Dihydropyridines; Heart Rate; Hypertension; | 1987 |
[Natriuretic effect of nifedipine in essential arterial hypertension].
Topics: Humans; Hypertension; Kidney Tubules, Distal; Natriuresis; Nifedipine | 1987 |
[Incidence and treatment of arterial hypertension in an emergency service].
Topics: Adult; Aged; Aged, 80 and over; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nifedi | 1987 |
A circulating hypertensive factor in primary hypertension: effect of antihypertensive therapy.
Topics: Adrenalectomy; Animals; Blood Proteins; Cross Circulation; Hypertension; Male; Nephrectomy; Nifedipi | 1987 |
Use of nicardipine in the anesthetic management of pheochromocytoma.
Topics: Adult; Anesthesia, Local; Blood Pressure; Cardiac Output; Epinephrine; Female; Fentanyl; Heart Rate; | 1986 |
High performance liquid chromatography analysis of nifedipine and some of its metabolites in hypertensive patients.
Topics: Aged; Biotransformation; Chromatography, High Pressure Liquid; Female; Humans; Hypertension; Male; M | 1986 |
Effect of nifedipine on calcium-induced contractions to potassium in the aorta and mesenteric arteries of spontaneously hypertensive and normotensive rats.
Topics: Animals; Aorta, Thoracic; Calcium; Hypertension; In Vitro Techniques; Mesenteric Arteries; Muscle Co | 1986 |
Role of nifedipine sublingually in accelerated hypertension.
Topics: Adolescent; Adult; Aged; Child; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1986 |
An audit of nifedipine in a hypertension clinic.
Topics: Age Factors; Aged; Blood Pressure; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fema | 1986 |
Influence of long-term antihypertensive therapy on cardiac function, coronary flow and myocardial oxygen consumption in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Coronary Circulation; Felodipine; Heart; Heart Rat | 1986 |
Cardiovascular effects of NPK-1886, a new dihydropyridine compound with calcium entry blocking activity.
Topics: Action Potentials; Animals; Blood Pressure; Calcium Channel Blockers; Cardiovascular System; Dihydro | 1986 |
[A new approach to the evaluation of hypertensive disease].
Topics: Acebutolol; Blood Pressure Determination; Humans; Hypertension; Monitoring, Physiologic; Nifedipine; | 1986 |
The efficacy and safety of long-term antihypertensive therapy with nifedipine.
Topics: Adult; Aged; Benzothiadiazines; Blood Glucose; Blood Pressure; Creatinine; Diuretics; Drug Evaluatio | 1986 |
Pharmacokinetics and pharmacodynamics of conventional and slow release forms of nifedipine in essential hypertensive patients.
Topics: Adult; Delayed-Action Preparations; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Nifed | 1986 |
An easy way to administer sublingual nifedipine.
Topics: Humans; Hypertension; Intraoperative Complications; Nifedipine | 1986 |
Nifedipine or verapamil counteracts hypertension in gravid ewes.
Topics: Animals; Blood Gas Analysis; Female; Hypertension; Nifedipine; Norepinephrine; Pre-Eclampsia; Pregna | 1986 |
The effects of nifedipine on regional vascular resistance and blood flow in the spontaneously hypertensive rat.
Topics: Animals; Blood Pressure; Cardiac Output; Hypertension; Male; Nifedipine; Rats; Rats, Inbred SHR; Rat | 1986 |
Effect of sodium balance and calcium channel-blocking drugs on plasma aldosterone responses to infusion of angiotensin II in normal subjects and patients with essential hypertension.
Topics: Adult; Aldosterone; Angiotensin II; Calcium; Calcium Channel Blockers; Diet, Sodium-Restricted; Dilt | 1986 |
[Treatment of hypertension with the calcium antagonist korinfar and its combination with obzidan].
Topics: Adult; Calcium Channel Blockers; Chronic Disease; Drug Evaluation; Drug Therapy, Combination; Hemody | 1986 |
Management of perioperative hypertension using sublingual nifedipine. Experience in elderly patients undergoing eye surgery.
Topics: Aged; Aged, 80 and over; Blood Pressure; Cataract Extraction; Female; Humans; Hypertension; Intraope | 1986 |
Conduction abnormalities due to nifedipine.
Topics: Heart Conduction System; Humans; Hypertension; Male; Nifedipine | 1986 |
[Effect of nifedipine on platelet function].
Topics: Adult; Aged; Coronary Disease; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Platelet | 1986 |
[Korinfar in the treatment of patients with arterial hypertension].
Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Eva | 1986 |
Felodipine compared to nifedipine as "third-line drug" in resistant hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Drug Evaluation; Drug Resistance; Felodipine; | 1986 |
Dose initiation of calcium antagonists in the treatment of hypertension.
Topics: Adult; Aged; Aged, 80 and over; Calcium Channel Blockers; Delayed-Action Preparations; Female; Human | 1986 |
Role of calcium channel blockade in chronic hypertension following successful management of hypertensive emergency.
Topics: Blood Pressure; Calcium Channel Blockers; Emergencies; Female; Follow-Up Studies; Humans; Hypertensi | 1986 |
[Hemodynamic mechanisms of the hypotensive action of the new calcium antagonist foridon in acute hypertension in rabbits. A comparison with nifedipine].
Topics: Acute Disease; Animals; Antihypertensive Agents; Calcium Channel Blockers; Drug Evaluation, Preclini | 1986 |
The metabolism of nifedipine during long-term therapy.
Topics: Chemical Phenomena; Chemistry; Female; Humans; Hypertension; Male; Nifedipine; Osmolar Concentration | 1986 |
Does a diuretic cause a further fall in blood pressure in hypertensive patients already on nifedipine?
Topics: Adult; Aged; Bendroflumethiazide; Blood Pressure; Drug Evaluation; Drug Therapy, Combination; Female | 1986 |
[Treatment of hypertensive emergencies with sublingual nifedipine].
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Blood Pressure; Emergencies; Female; Humans; H | 1986 |
[Enhanced hypotensive effect of long-acting nifedipine on elder patients with mild or moderate essential hypertension].
Topics: Adult; Age Factors; Aged; Aging; Benzothiadiazines; Delayed-Action Preparations; Diuretics; Drug The | 1986 |
Nifedipine therapy of phenylpropanolamine-induced hypertension.
Topics: Administration, Oral; Adolescent; Adolescent Behavior; Female; Hemodynamics; Humans; Hypertension; N | 1987 |
Effects of the calcium antagonist nifedipine on thromboxane B2 level and platelet aggregation in hypertensive patients.
Topics: Adenosine Diphosphate; Aged; Blood Pressure; Creatine Kinase; Humans; Hypertension; L-Lactate Dehydr | 1986 |
Comparative effects on blood pressure of different calcium-blocking agents.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Diltiazem; Diuretics; Female; Humans; Hypertension; | 1986 |
Slow-release nifedipine associated with muzolimine in the treatment of mild to moderate essential hypertension.
Topics: Adult; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; M | 1986 |
Calcium channel blockers and peripheral arterial flow in normal and in hypertensive subjects.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1986 |
Hemodynamic effects of acute administration of slow-release nifedipine in elderly patients with systolic hypertension.
Topics: Aged; Blood Pressure; Delayed-Action Preparations; Female; Heart Rate; Hemodynamics; Humans; Hyperte | 1986 |
Symptomatic hypotension induced by nifedipine in the acute treatment of severe hypertension.
Topics: Female; Humans; Hypertension; Hypotension; Male; Middle Aged; Nifedipine | 1987 |
[Experimental models of the use of calcium antagonists in arterial hypertension].
Topics: Animals; Blood Pressure; Heart Rate; Hypertension; Hypertension, Renovascular; Male; Nifedipine; Rat | 1986 |
[Nifedipine treatment of hypertensive crisis in the aged].
Topics: Administration, Oral; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Nifedipine; Time Fac | 1985 |
Calcium antagonists: hypotensive and humoral actions in different forms of hypertension.
Topics: Calcium; Calcium Channel Blockers; Emergencies; Heart Rate; Homeostasis; Hormones; Humans; Hypertens | 1985 |
Drugs for hypertensive emergencies.
Topics: Administration, Oral; Captopril; Clonidine; Diazoxide; Emergencies; Humans; Hydralazine; Hypertensio | 1985 |
Salt-induced hypertension in the 'Sabra' rat strain: influence of nifedipine treatment.
Topics: Aldosterone; Animals; Blood Pressure; Body Weight; Hypertension; Male; Myocardium; Nifedipine; Organ | 1985 |
Felodipine. A calcium-inhibiting vasodilator in refractory hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Felodipine; Female; | 1985 |
Effects of nifedipine on insulin secretion and glucose metabolism in rats and in hypertensive type 2 (non-insulin dependent) diabetics.
Topics: Aged; Animals; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Tolerance Test; Glycated Hemoglob | 1985 |
Vasodilatory effect of nicardipine and verapamil in the forearm of hypertensive as compared with normotensive man.
Topics: Adult; Aged; Blood Pressure; Calcium Channel Blockers; Forearm; Humans; Hypertension; Middle Aged; N | 1985 |
Calcium channel blockers--are they diuretics?
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Diuretics; Female; Humans; Hypertension; Kidney Tub | 1985 |
Oral nifedipine for the treatment of patients with severe hypertension.
Topics: Administration, Oral; Adult; Aged; Blood Pressure; Cardiac Output; Female; Humans; Hypertension; Mal | 1985 |
[Evaluation of the antihypertensive effectiveness of nifedipine at rest and after exertion. Variation of plasma renin activity and plasma lipids during the treatment interval].
Topics: Adult; Blood Pressure; Evaluation Studies as Topic; Humans; Hypertension; Lipids; Male; Middle Aged; | 1985 |
Cardiovascular, baroreflex and humoral responses in hypertensive patients during nicardipine therapy.
Topics: Adult; Aldosterone; Carotid Arteries; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle A | 1985 |
Body sodium-blood volume state, aldosterone, and cardiovascular responsiveness after calcium entry blockade with nifedipine.
Topics: Aged; Aldosterone; Angiotensin II; Blood Volume; Calcium; Chlorthalidone; Drug Therapy, Combination; | 1985 |
[Therapeutic approach to arterial hypertension: comparison and combination of acebutolol with nifedipine and captopril].
Topics: Acebutolol; Captopril; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hypertension; Mal | 1985 |
Effects of felodipine on resistance and capacitance vessels in patients with essential hypertension.
Topics: Adult; Aged; Antihypertensive Agents; Atenolol; Blood Pressure; Blood Vessels; Electrocardiography; | 1985 |
Treatment of a phaeochromocytoma of the urinary bladder with nifedipine.
Topics: Adult; Female; Humans; Hypertension; Nifedipine; Pheochromocytoma; Urinary Bladder Neoplasms | 1985 |
Calcium channel blocking agents and the heart.
Topics: Hematocrit; Humans; Hypertension; Nifedipine | 1985 |
Calcium-channel blockers in acute hypertension.
Topics: Acute Disease; Blood Pressure; Calcium Channel Blockers; Costs and Cost Analysis; Emergencies; Heart | 1985 |
Managing acute hypertension: cost considerations.
Topics: Acute Disease; California; Cost-Benefit Analysis; Drug Utilization; Emergencies; Humans; Hypertensio | 1985 |
[Acute effect of nifedipine on arterial pressure and the renin-angiotensin system in healthy subjects and hypertensives].
Topics: Adolescent; Adult; Aged; Aldosterone; Blood Pressure; Female; Heart Rate; Humans; Hypertension; Male | 1985 |
[Central and peripheral hemodynamic effects of nifedipine administered orally and sublingually in essential arterial hypertension].
Topics: Administration, Oral; Adult; Arteries; Blood Flow Velocity; Compliance; Forearm; Hemodynamics; Human | 1985 |
[Effect of nifedipine on arterial pressure and control of the cardiac reflex].
Topics: Adult; Cardiac Output; Cold Temperature; Female; Humans; Hypertension; Isometric Contraction; Male; | 1985 |
[Acute and chronic effects of a new calcium blocker, nicardipine, on renal hemodynamics in arterial hypertension].
Topics: Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; Nifedipine; | 1985 |
A study of the long-term efficacy and tolerability of oral nicardipine in hypertensive patients.
Topics: Administration, Oral; Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Mid | 1985 |
Acute and chronic sympathetic reflex activation and antihypertensive response to nifedipine.
Topics: Adult; Blood Pressure; Blood Volume; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipi | 1986 |
Hypertensive crisis associated with nifedipine withdrawal.
Topics: Aged; Humans; Hypertension; Male; Nifedipine | 1986 |
On the mechanism of the anti-hypertensive effect of Ca++-blockers.
Topics: Anesthesia; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dogs; Heart | 1986 |
[Use of Nifedipine (Corinfar) in hypertensive emergencies].
Topics: Emergencies; Humans; Hypertension; Nifedipine | 1985 |
Treatment of arterial hypertension with nifedipine in patients with chronic renal insufficiency.
Topics: Blood Pressure; Delayed-Action Preparations; Dosage Forms; Humans; Hypertension; Kidney Failure, Chr | 1985 |
[Treatment of arterial hypertension with calcium antagonists].
Topics: Blood Volume; Cardiac Output; Heart Rate; Humans; Hypertension; Nifedipine; Vascular Resistance; Ver | 1985 |
[Effect of nifedipine (adalate) in neurology patients with arterial hypertension].
Topics: Adult; Aged; Cerebrovascular Circulation; Cerebrovascular Disorders; Chronic Disease; Female; Humans | 1985 |
Potential prevention of myocardial rupture resulting from acute myocardial infarction.
Topics: Adult; Aged; Angina Pectoris; Female; Heart Rupture; Heart Septum; Heart Ventricles; Humans; Hyperte | 1985 |
Forearm vascular responses in normotensives and hypertensives after sublingual nifedipine.
Topics: Administration, Oral; Adult; Blood Circulation; Capsules; Forearm; Heart Rate; Humans; Hypertension; | 1985 |
Effect of felodipine and metoprolol on muscle and skin arteries in hypertensive patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Heart Rate; Humans; Hypere | 1985 |
Haemodynamic effects of intravenous felodipine in normotensive and hypertensive subjects.
Topics: Adolescent; Adult; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Heart Rate; Hemodyna | 1985 |
Felodipine as an alternative to minoxidil in severe refractory hypertension.
Topics: Antihypertensive Agents; Blood Pressure; Drug Resistance; Felodipine; Humans; Hypertension; Male; Mi | 1985 |
Acute haemodynamic and platelet effects of felodipine in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Coagulation; Blood Platelets; Blood Pressure; Felodipine; Fema | 1985 |
Effects of felodipine on renal function in animals.
Topics: Animals; Antihypertensive Agents; Dogs; Felodipine; Glomerular Filtration Rate; Hemodynamics; Hydral | 1985 |
Antihypertensive and water and sodium balance effects of felodipine, a new vasodilating calcium antagonist, in hypertensive patients.
Topics: Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Creatinine; Felodipine; Fe | 1985 |
Renal effects of felodipine in hypertensive patients with reduced renal function.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Felodipine; Female; Glomerular Filtration Rate | 1985 |
Haemodynamic effects of short and long term administration of felodipine in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Cardiac Output; Coronary Circulation; Drug Administration Schedule | 1985 |
Nifedipine-induced periorbital edema.
Topics: Angina Pectoris; Edema; Female; Humans; Hypertension; Middle Aged; Nifedipine; Orbital Diseases | 1985 |
Nifedipine in antihypertensive therapy.
Topics: Humans; Hypertension; Nifedipine | 1985 |
Effect of nifedipine and propranolol on blood flow, venous compliance and blood pressure in essential hypertension.
Topics: Adult; Aged; Blood Pressure; Compliance; Drug Therapy, Combination; Forearm; Humans; Hypertension; M | 1985 |
Preoperative management of pheochromocytoma with the calcium-antagonist nifedipine.
Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Electrocardiography; Female; Humans; Hypertension; N | 1985 |
Nifedipine in the treatment of hypertension in the elderly.
Topics: Age Factors; Aged; Blood Pressure; Female; Humans; Hypertension; Male; Nifedipine; Time Factors | 1985 |
[Experiences with nifedipine in the treatment of acute hypertension in childhood].
Topics: Acute Disease; Blood Pressure; Child; Drug Therapy, Combination; Female; Humans; Hypertension; Male; | 1985 |
Effects of nifedipine and diltiazem on hemodynamic responses at rest and during exercise in hypertensive patients.
Topics: Adult; Aged; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Diltiazem; Fema | 1985 |
Comments on hypertension symposium.
Topics: Humans; Hypertension; Nifedipine; Prazosin | 1985 |
[The hypertensive emergency and severe hypertension: experiences with nifedipine].
Topics: Adult; Aged; Blood Pressure; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; Nifedipin | 1985 |
[Nifedipine in the hypertensive crisis--effect of intravenous administration].
Topics: Adult; Aged; Blood Pressure; Emergencies; Female; Humans; Hypertension; Infusions, Parenteral; Male; | 1985 |
[Nifedipine in therapy-resistant hypertension].
Topics: Aged; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Female; Humans; Hyp | 1985 |
Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases.
Topics: Adult; Aged; Angina Pectoris; Asthma; Cerebrovascular Disorders; Diabetes Complications; Edema; Fema | 1985 |
[The use of nifedipine in the treatment of hypertensive crises in patients with chronic uremia undergoing periodic hemodialysis].
Topics: Chronic Disease; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Renal Dialysis; Uremia | 1985 |
[Nifedipine drops in the treatment of hypertensive emergencies].
Topics: Administration, Oral; Emergencies; Female; Humans; Hypertension; Male; Nifedipine | 1985 |
Characteristic changes of plasma proteins in the Dahl hypertensive rat strain (DS) during the development of hypertension.
Topics: Animals; Blood Pressure; Blood Proteins; Electrophoresis, Polyacrylamide Gel; Female; Hypertension; | 1985 |
[Effect of korinfar on the central and peripheral hemodynamics of hypertension patients].
Topics: Adult; Calcium Channel Blockers; Drug Evaluation; Hemodynamics; Humans; Hypertension; Male; Middle A | 1985 |
The effect of acute and chronic nicardipine therapy on forearm arterial haemodynamics in essential hypertension.
Topics: Blood Pressure; Calcium; Calcium Channel Blockers; Female; Forearm; Heart Rate; Hemodynamics; Humans | 1985 |
The effect of nicardipine on blood pressure, its variability and reflex cardiac control.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Female; Heart Rate; Humans; Hypertension; Male; Mid | 1985 |
Nifedipine in hemodialyzed patients.
Topics: Female; Humans; Hypertension; Male; Nifedipine; Renal Dialysis | 1985 |
[Efficacy of treatment with hydroalcoholic solutions of nifedipine in various cardiovascular emergencies].
Topics: Adult; Aged; Coronary Disease; Emergencies; Ethanol; Female; Humans; Hypertension; Male; Middle Aged | 1985 |
Afterload reduction by nifedipine--the acute haemodynamic response to exercise in hypertensive subjects.
Topics: Adult; Atenolol; Blood Pressure; Cardiac Output; Drug Therapy, Combination; Exercise Test; Hemodynam | 1985 |
[Antihypertensive effect of nasal nifedipine and its plasma concentration during anesthesia and surgery].
Topics: Administration, Intranasal; Adult; Aged; Antihypertensive Agents; Blood Pressure; Female; Humans; Hy | 1985 |
Syncope and conduction disturbances following sublingual nifedipine for hypertension.
Topics: Aged; Blood Pressure; Emergencies; Epistaxis; Female; Heart Block; Humans; Hypertension; Nifedipine; | 1985 |
Healing of malignant hypertensive arteriopathy in Dahl rats by nifedipine.
Topics: Animals; Blood Pressure; Female; Hypertension; Mesenteric Arteries; Nifedipine; Rats; Sodium Chlorid | 1985 |
[Therapeutic effect of nifedipine in the treatment of systemic hypertension].
Topics: Adult; Aged; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; | 1985 |
Pharmacokinetics of nifedipine and prediction of plasma concentration on essential hypertensive patients.
Topics: Adult; Drug Administration Schedule; Female; Humans; Hypertension; Kinetics; Male; Middle Aged; Nife | 1985 |
Effect of nifedipine on cellular electrolytes in fourteen patients with untreated primary hypertension.
Topics: Adult; Blood Pressure; Calcium; Electrolytes; Erythrocytes; Female; Humans; Hypertension; Male; Midd | 1985 |
Hemodynamic effects of calcium channel blockers at rest and during exercise in essential hypertension.
Topics: Adult; Calcium Channel Blockers; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; | 1985 |
Treatment of hypertensive emergencies with the calcium channel blocker nifedipine.
Topics: Blood Pressure; Cerebrovascular Circulation; Emergencies; Humans; Hypertension; Nifedipine | 1985 |
[Treatment of arterial hypertension with a calcium-channel blocking agent, nicardipine hydrochloride].
Topics: Adult; Aged; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nicardipine; | 1985 |
Control of hypertension with nifedipine in the setting of aortic dissection.
Topics: Aortic Aneurysm; Aortic Dissection; Asthma; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1985 |
[Effect of nicardipine on cholesterol-fed S.H.R].
Topics: Animals; Aorta; Arteriosclerosis; Body Weight; Heart Rate; Hyperlipidemias; Hypertension; Lipids; Li | 1985 |
[Treatment of hypertensive crisis with sublingual nifedipine].
Topics: Administration, Oral; Female; Humans; Hypertension; Male; Mouth Floor; Nifedipine | 1985 |
Nifedipine in the management of hypertensive emergencies: report of two cases and review of the literature.
Topics: Administration, Oral; Aged; Blood Pressure; Cardiac Output; Cerebrovascular Disorders; Emergencies; | 1985 |
Nicardipine and nifedipine: effects on diuresis and serum aldosterone levels in spontaneously hypertensive rats.
Topics: Aldosterone; Animals; Blood Pressure; Diuresis; Hypertension; Male; Nicardipine; Nifedipine; Rats; R | 1985 |
[Hypertensive crisis during E.P.H. gestosis treated with sublingual nifedipine. Report of a case].
Topics: Administration, Oral; Adolescent; Female; Humans; Hypertension; Nifedipine; Pre-Eclampsia; Pregnancy | 1985 |
[Nifedipine in short supply].
Topics: Angina Pectoris; Humans; Hungary; Hypertension; Nifedipine | 1985 |
Oral nifedipine in hypertensive emergencies.
Topics: Adolescent; Adult; Blood Pressure; Child; Emergencies; Female; Humans; Hypertension; Male; Middle Ag | 1985 |
[Management of hypertensive crises with corinfar].
Topics: Adult; Aged; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine | 1985 |
Use of the calcium-channel blocker nifedipine in the management of hypertensive emergency.
Topics: Adult; Aged; Blood Pressure; Capsules; Emergencies; Female; Humans; Hypertension; Male; Middle Aged; | 1985 |
[Pharmacological studies on pinacidil, a new anti-hypertensive agent. 1. Antihypertensive effects in SHR and DOC/saline hypertensive rats].
Topics: Administration, Oral; Animals; Antihypertensive Agents; Desoxycorticosterone; Female; Guanidines; Hy | 1985 |