Page last updated: 2024-11-01

nifedipine and Bleeding

nifedipine has been researched along with Bleeding in 7 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality."8.79Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995)
" hypertension clinical trial databases for amlodipine (Norvasc) and nifedipine in the gastrointestinal therapeutic system (GITS) formulation (Procardia XL)."4.80Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients. ( Kloner, RA; Levenstein, M; Materson, BJ; Vetrovec, GW, 1998)
"In patients with coronary disease, the use of short-acting nifedipine in moderate to high doses causes an increase in total mortality."4.79Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. ( Furberg, CD; Meyer, JV; Psaty, BM, 1995)
"To present cases in whom purpura or internal bleeding due to calcium-channel blockers was a presenting feature, including one subject with drug-induced haematuria and haematospermia due to amlodipine and one with the Rumpel-Leede sign."3.75Purpura and bleeding due to calcium-channel blockers: an underestimated problem? Case reports and a pilot study. ( Cox, NH; Robson, RH; Walsh, ML, 2009)
"Systemic hemodynamics and hepatic macro- and microcirculation (ultrasonic technique, biomicroscopy) were studied in intact rats and rats with acute massive hemorrhage after intravenous administration of the calcium antagonists verapamil and nifedipine."3.68[The effect of verapamil and nifedipine on the systemic hemodynamics and liver macro- and microcirculations in rats with acute massive blood loss]. ( Kovalenko, NIa; MatsievskiÄ­, DD, 1993)
" In one protocol, hemorrhage produced a complete resetting to hypotension in rats chronically treated (6 days) with captopril."3.68Antihypertensive drugs distinctly modulate the rapid resetting of the baroreceptors. ( de Abreu, GR; Salgado, HC, 1990)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (71.43)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Skalias, A1
Karamitsou, P1
Mitos, G1
Zarzava, E1
Tsapara, V1
Poutoglidis, A1
Gougousis, S1
Cox, NH1
Walsh, ML1
Robson, RH1
Opie, LH1
Messerli, FH1
Furberg, CD1
Psaty, BM1
Meyer, JV1
Kovalenko, NIa1
MatsievskiÄ­, DD1
Kloner, RA1
Vetrovec, GW1
Materson, BJ1
Levenstein, M1
de Abreu, GR1
Salgado, HC1

Reviews

2 reviews available for nifedipine and Bleeding

ArticleYear
Nifedipine. Dose-related increase in mortality in patients with coronary heart disease.
    Circulation, 1995, Sep-01, Volume: 92, Issue:5

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Confidence Intervals; Coronary Dise

1995
Safety of long-acting dihydropyridine calcium channel blockers in hypertensive patients.
    The American journal of cardiology, 1998, Jan-15, Volume: 81, Issue:2

    Topics: Amlodipine; Calcium Channel Blockers; Cause of Death; Cerebrovascular Disorders; Clinical Trials as

1998

Trials

1 trial available for nifedipine and Bleeding

ArticleYear
Does preoperative administration of hypotensive agents affect the quality of the surgical field during endoscopic sinus surgery? A triple-blind randomized controlled trial.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2023, Volume: 280, Issue:10

    Topics: Bisoprolol; Blood Loss, Surgical; Endoscopy; Hemorrhage; Humans; Nifedipine; Prospective Studies; Si

2023

Other Studies

4 other studies available for nifedipine and Bleeding

ArticleYear
Purpura and bleeding due to calcium-channel blockers: an underestimated problem? Case reports and a pilot study.
    Clinical and experimental dermatology, 2009, Volume: 34, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Calcium Channel Blockers; Female; Hemorrhage; Humans; Male; Mid

2009
Nifedipine and mortality. Grave defects in the dossier.
    Circulation, 1995, Sep-01, Volume: 92, Issue:5

    Topics: Angina Pectoris; Arrhythmias, Cardiac; Autonomic Nervous System; Calcium Channel Blockers; Coronary

1995
[The effect of verapamil and nifedipine on the systemic hemodynamics and liver macro- and microcirculations in rats with acute massive blood loss].
    Biulleten' eksperimental'noi biologii i meditsiny, 1993, Volume: 116, Issue:11

    Topics: Acute Disease; Animals; Cardiovascular Physiological Phenomena; Cardiovascular System; Drug Evaluati

1993
Antihypertensive drugs distinctly modulate the rapid resetting of the baroreceptors.
    Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:2 Suppl

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Carotid Arteries; Hemorrhage; Male; Nif

1990