Page last updated: 2024-11-01

nifedipine and Asthma

nifedipine has been researched along with Asthma in 103 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).

Research Excerpts

ExcerptRelevanceReference
"Incidence, frequency, and severity of persistent cough, pulmonary functions, and bronchial hyperresponsiveness did not change in either the candesartan or calcium antagonist group."9.09Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma. ( Abe, S; Hashimoto, M; Oashi, K; Saikai, T; Suzuki, K; Tanaka, H; Tanaka, S; Teramoto, S, 2001)
"Twenty patients of bronchial asthma were given 5 mg of either nifedipine or verapamil as aerosol therapy in a randomized fashion."9.07Effect of aerosolised verapamil and nifedipine in bronchial asthma. ( Bidani, R; Chopra, R; Gupta, S; Meena, HS, 1993)
"The effect of nifedipine on serum theophylline levels in 13 female hypertensive patients having asthma on theophylline therapy has been investigated."9.07Nifedipine alters serum theophylline levels in asthmatic patients with hypertension. ( Canberk, A; Eroğlu, L; Yilmaz, E, 1991)
"The clinical effects of a calcium antagonist--nifedipine on Xinjiang local pollen sensitive asthmatics were reported."9.06[Effects of nifedipine on pollen-antigen-induced bronchoconstriction in asthmatics]. ( Zhang, XL, 1989)
"The protective effect of nifedipine and diltiazem on methacholine-induced bronchoconstriction was studied in 12 allergic asthmatic patients."9.06Differential effects of nifedipine and diltiazem on methacholine-induced bronchospasm in allergic asthma. ( De Gasperi, M; Ferrari, M; Lechi, A; Olivieri, M, 1989)
"Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma."9.06Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987)
"In order to study the dose-related effect of nifedipine on expiratory flow rates, 15 asthmatic patients were given sublingually 10 mg and 20 mg of the drug on two different days and the FVC and FEV1 were measured during 90 minutes."9.06Nifedipine in asthma. Dose-related effect on resting bronchial tone. ( Chaniac, A; Gruzman, C; Katz, I; Lidgi, M; Molho, M, 1987)
" To test whether nifedipine reduces corticosteroid requirements of patients with asthma, a 16-week double-blind crossover trial comparing nifedipine with placebo was performed."9.06Nifedipine in corticosteroid-dependent asthma: preliminary study. ( al-Waili, NS, 1989)
"Four patients with documented exercise-induced asthma (EIA) were pretreated orally in random, double-blind fashion with the calcium channel blockers nifedipine 20 mg and flordipine 25 and 50 mg and placebo, then subjected to exercise challenge on a cycloergometer."9.06Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma. ( Gordon, EH; Klaustermeyer, WB; Wong, SC, 1987)
"To investigate whether the effects of nifedipine on methacholine induced broncho-constriction could impair pulmonary gas exchange in bronchial asthma a randomised, double blind, crossover study in 13 symptom free asthmatic subjects was designed."9.06Effect of nifedipine on arterial hypoxaemia occurring after methacholine challenge in asthma. ( Agusti-Vidal, A; Ballester, E; Roca, J; Rodriguez-Roisin, R, 1986)
"The effect on bronchial smooth muscle of slow release theophylline plus placebo and theophylline plus slow release nifedipine administered for a prolonged period to 12 asthmatic and hypertensive patients has been studied."9.06Long-term treatment with oral nifedipine plus theophylline in the management of chronic bronchial asthma. ( Lombardi, C; Spedini, C, 1986)
"A randomized double-blind crossover trial with nifedipine (10 mg orally four times a day for 2 weeks) was carried out in 11 asthmatic patients."9.06Therapy with nifedipine in asthma: a randomized double-blind crossover trial. ( Benzaray, S; Chagnac, A; Katz, I; Lidji, M; Molho, M, 1988)
"This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA)."9.06The effect of nifedipine on exercise-induced asthma. ( Guleria, JS; Pande, JN; Sharma, SK, 1986)
" for 2 weeks, was studied in a randomized, double-blind, crossover trial in nine patients with asthma receiving theophylline."9.06Effect of nifedipine and theophylline in asthma. ( Cohen, E; Garty, M; Ilfeld, DN; Mazar, A; Rosenfeld, JB; Spitzer, S, 1986)
" The effect of three single doses of nifedipine on exercise-induced asthma has been examined in 11 asthmatic subjects."9.06Inhibition of exercise-induced asthma by nifedipine: a dose-response study. ( Edwards, JS; Holgate, ST; Rafferty, P; Varley, JG, 1987)
"The effect of adding slow release nifedipine to oral theophylline has been studied in eight patients with stable but symptomatic asthma, a double blind placebo controlled crossover protocol being used."9.06Effect of nifedipine on serum theophylline concentrations and asthma control. ( Kendall, MJ; Skinner, C; Smith, SR; Stableforth, DE; Wiggins, J, 1987)
"The effect of pretreatment with nifedipine 20 mg sublingually on the bronchoconstrictor response to inhaled histamine and methacholine in asthmatic and normal subjects has been studied."9.06The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects. ( Costello, JF; Henderson, AF, 1988)
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo."9.05Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983)
"Seven asthmatic patients were studied in a single-blind randomized, crossover study after oral administration of 20 mg nifedipine or placebo."9.05Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline. ( Löfdahl, CG; Svedmyr, K; Svedmyr, N, 1984)
"The nifedipine effect was studied in 8 extrinsic asthmatic subjects with exercise-induced asthma."9.05Effect of a calcium antagonist, nifedipine, in exercise-induced asthma. ( Crimi, N; Gibellino, F; Mistretta, A; Palermo, F; Sorace, R, 1984)
"In 11 patients with bronchial asthma and regular overnight falls in PEFR of greater than 15%, we demonstrated significant bronchodilation restricted only to large airways after the administration of a single dose of 10 mg of nifedipine."9.05Nifedipine in bronchial asthma. ( Argiropoulou, P; Louridas, G; Patakas, D; Tsara, V; Vlachoianni, E, 1983)
"Calcium-channel blockers such as verapamil and nifedipine have been shown to inhibit exercise-induced asthma as well as acutely induced bronchoconstriction, but little is known of their chronic effects, if any, on bronchial asthma."9.05Nifedipine in chronic bronchial asthma: a randomized double-blind crossover trial against placebo. ( Boismare, F; Lemercier, JP; Leprevost, A; Moore, ND; Ozenne, G; Pasquis, P; Tardif, C, 1985)
"RWJ 22108 (N-benzyl-N-methylaminoethyl 9-(2-chloro-6-fluorophenyl)-2,3,4,5,6,9-hexahydro-7-methyl-1, 1-dioxothiacyclohepteno-[3,2-b]pyridine-8-carboxylate) is a new bronchoselective calcium entry blocker with potential use as an antiasthmatic agent."7.68Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker. ( Ahmed, T; Anderson, DW; Capetola, RJ; Dodd, JH; Kirchner, T; Moore, JB; Ritchie, DM, 1993)
"A study was made of the impact of a single intake of nifedipine, intal, sodium thiosulfate and essentiale on respiratory function, the blood content of ionized calcium, total calcium, hydroperoxides, total and non-protein thiol groups, and prostaglandins in bronchial asthma patients."7.68[The effect of a single dose of nifedipine, intal, sodium thiosulfate and Essentiale on the blood level of calcium, hydroperoxides, thiol compounds and prostaglandins in bronchial asthma patients]. ( Amatuni, VG; Malaian, KL; Zakaharian, AK, 1992)
"In the asthmatic model mainly mediated by the endogenous slow reacting substance of anaphylaxis (SRS-A) induced by the antigen inhalation to passively sensitized guinea pigs, continuous intravenous infusion of nifedipine (Adalat) at a speed of 7 micrograms/kg/min depressed the airway open pressure by about 68% compared to the saline-treated group and produced a delay in the time to peak response."7.67Effect of a Ca2+ antagonist, nifedipine, on the experimental asthma mediated mainly by slow reacting substance of anaphylaxis. ( Fujimura, M; Ishizaki, T; Kanamori, K; Koshino, T; Matsuda, T; Minami, S; Miyabo, S; Nishioka, S; Okafuji, K; Saga, T, 1985)
"Marked improvement in the respiratory status of two patients with chronic obstructive lung disease was observed during treatment with nifedipine for angina pectoris."7.67Exacerbation of asthmatic symptoms after cessation of nifedipine therapy. ( Eliraz, A; Fink, A; Wishnitzer, R, 1984)
"This prospective study was undertaken to evaluate the safety of nifedipine, a calcium channel blocking agent, on 60 subjects with asthma, chronic obstructive pulmonary disease (COPD), angina, and normal subjects."7.67Safety of nifedipine in subjects with bronchial asthma and COPD. ( Bewtra, A; Nair, CK; Nair, N; Townley, RG, 1984)
"The combined effect of oral nifedipine and aerosolized sodium cromoglycate on the airway response to inhaled sodium chloride at increasing concentrations was randomly studied in 10 patients with bronchial asthma."7.67The combined effect of nifedipine and sodium cromoglycate on the airway response to inhaled hypertonic saline in patients with bronchial asthma. ( Ganem, R; Greif, J; Kivity, S; Topilsky, M, 1989)
"The inhibitory effect of nicardipine, a calcium antagonist, on the antigen- and anti-IgE-induced histamine release from basophilic leucocytes of patients with bronchial asthma was examined."7.67The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics. ( Kimura, I; Kitani, H; Komagoe, H; Maeda, M; Morinaga, H; Nakagawa, S; Ohtani, J; Takahashi, K; Tanizaki, Y, 1985)
"The protective effect of the calcium antagonist nifedipine (20 mg sublingually) on methacholine-induced bronchospasms was investigated in 14 mild asthmatics, 8 extrinsic and 6 intrinsic, in stable situations and with FEV1 greater than or equal to 80% of the one predicted."7.67Nifedipine decreases sensitivity and reactivity to methacholine in mild asthmatics. ( Marco, V; Pellicer, C; Perpiñá, M, 1987)
"The effect of nifedipine was studied in fifteen patients with exercise-induced asthma."7.66The effect of calcium antagonist, nifedipine in exercise-induced asthma. ( Patel, KR, 1981)
"When diltiazem was given alone, it had no effect on the airway but, when given with nifedipine, it significantly raised the PC20 to methacholine."6.67Combined effect of nifedipine and diltiazem on methacholine-induced bronchoconstriction in asthmatic patients. ( Brayer, M; Kivity, S; Topilsky, M, 1992)
"Pretreatment with nifedipine significantly attenuated acetylcholine-induced changes in all four lung function parameters studied, but did not significantly influence the increase in thromboxane B2 plasma concentrations observed after the acetylcholine challenge."6.66Inhibition of acetylcholine-induced bronchoconstriction in asthmatics by nifedipine. ( Burghuber, OC; Haber, P; Harmuth, P; Kneussl, M; Silberbauer, K; Sinzinger, H, 1986)
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma."6.65A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981)
"Twenty-one otherwise healthy adults with persistent asthma, mean age 25 years, completed treatment with maximum tolerated doses of placebo (P), nifedipine (N), and diltiazem (D) in a double-blind, randomized, three-treatment, three-period, crossover manner, each for 4 weeks."5.10Efficacy of calcium channel blockers as maintenance therapy for asthma. ( Ann Twiss, M; Chesrown, S; Harman, E; Hendeles, L, 2002)
"Incidence, frequency, and severity of persistent cough, pulmonary functions, and bronchial hyperresponsiveness did not change in either the candesartan or calcium antagonist group."5.09Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma. ( Abe, S; Hashimoto, M; Oashi, K; Saikai, T; Suzuki, K; Tanaka, H; Tanaka, S; Teramoto, S, 2001)
"Twenty patients of bronchial asthma were given 5 mg of either nifedipine or verapamil as aerosol therapy in a randomized fashion."5.07Effect of aerosolised verapamil and nifedipine in bronchial asthma. ( Bidani, R; Chopra, R; Gupta, S; Meena, HS, 1993)
"The effect of nifedipine on serum theophylline levels in 13 female hypertensive patients having asthma on theophylline therapy has been investigated."5.07Nifedipine alters serum theophylline levels in asthmatic patients with hypertension. ( Canberk, A; Eroğlu, L; Yilmaz, E, 1991)
"This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA)."5.06The effect of nifedipine on exercise-induced asthma. ( Guleria, JS; Pande, JN; Sharma, SK, 1986)
"The effect on bronchial smooth muscle of slow release theophylline plus placebo and theophylline plus slow release nifedipine administered for a prolonged period to 12 asthmatic and hypertensive patients has been studied."5.06Long-term treatment with oral nifedipine plus theophylline in the management of chronic bronchial asthma. ( Lombardi, C; Spedini, C, 1986)
"We have investigated the effect of nifedipine on acetylcholine-induced bronchoconstriction in 8 asthmatics and on histamine-induced bronchoconstriction in another 8 asthmatics on a single-blind basis."5.06Effect of nifedipine on dose-response curves to acetylcholine and histamine measured during quiet breathing. ( Arai, M; Fueki, R; Kobayashi, S; Kuroiwa, H; Tomioka, S, 1986)
"Inhaled adenosine causes bronchoconstriction in asthmatic patients."5.06Effect of sodium cromoglycate and nifedipine on adenosine-induced bronchoconstriction. ( Crimi, N; Distefano, SM; Mistretta, A; Oliveri, R; Palermo, F; Polosa, R; Vancheri, C, 1988)
"The protective effect of nifedipine and diltiazem on methacholine-induced bronchoconstriction was studied in 12 allergic asthmatic patients."5.06Differential effects of nifedipine and diltiazem on methacholine-induced bronchospasm in allergic asthma. ( De Gasperi, M; Ferrari, M; Lechi, A; Olivieri, M, 1989)
"In order to study the dose-related effect of nifedipine on expiratory flow rates, 15 asthmatic patients were given sublingually 10 mg and 20 mg of the drug on two different days and the FVC and FEV1 were measured during 90 minutes."5.06Nifedipine in asthma. Dose-related effect on resting bronchial tone. ( Chaniac, A; Gruzman, C; Katz, I; Lidgi, M; Molho, M, 1987)
" To test whether nifedipine reduces corticosteroid requirements of patients with asthma, a 16-week double-blind crossover trial comparing nifedipine with placebo was performed."5.06Nifedipine in corticosteroid-dependent asthma: preliminary study. ( al-Waili, NS, 1989)
"The clinical effects of a calcium antagonist--nifedipine on Xinjiang local pollen sensitive asthmatics were reported."5.06[Effects of nifedipine on pollen-antigen-induced bronchoconstriction in asthmatics]. ( Zhang, XL, 1989)
"The effect of pretreatment with nifedipine 20 mg sublingually on the bronchoconstrictor response to inhaled histamine and methacholine in asthmatic and normal subjects has been studied."5.06The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects. ( Costello, JF; Henderson, AF, 1988)
"A randomized double-blind crossover trial with nifedipine (10 mg orally four times a day for 2 weeks) was carried out in 11 asthmatic patients."5.06Therapy with nifedipine in asthma: a randomized double-blind crossover trial. ( Benzaray, S; Chagnac, A; Katz, I; Lidji, M; Molho, M, 1988)
"Nifedipine, 30 mg/day for 4 weeks, was compared to placebo in a double-blind, randomized, crossover study, as an additional drug added to the usual treatment of 14 patients with bronchial asthma."5.06Nifedipine treatment of patients with bronchial asthma. ( Dascalopoulou, E; Maniki, E; Patakas, D; Tsara, V, 1987)
"The effect of adding slow release nifedipine to oral theophylline has been studied in eight patients with stable but symptomatic asthma, a double blind placebo controlled crossover protocol being used."5.06Effect of nifedipine on serum theophylline concentrations and asthma control. ( Kendall, MJ; Skinner, C; Smith, SR; Stableforth, DE; Wiggins, J, 1987)
"Four patients with documented exercise-induced asthma (EIA) were pretreated orally in random, double-blind fashion with the calcium channel blockers nifedipine 20 mg and flordipine 25 and 50 mg and placebo, then subjected to exercise challenge on a cycloergometer."5.06Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma. ( Gordon, EH; Klaustermeyer, WB; Wong, SC, 1987)
"To investigate whether the effects of nifedipine on methacholine induced broncho-constriction could impair pulmonary gas exchange in bronchial asthma a randomised, double blind, crossover study in 13 symptom free asthmatic subjects was designed."5.06Effect of nifedipine on arterial hypoxaemia occurring after methacholine challenge in asthma. ( Agusti-Vidal, A; Ballester, E; Roca, J; Rodriguez-Roisin, R, 1986)
" The effect of three single doses of nifedipine on exercise-induced asthma has been examined in 11 asthmatic subjects."5.06Inhibition of exercise-induced asthma by nifedipine: a dose-response study. ( Edwards, JS; Holgate, ST; Rafferty, P; Varley, JG, 1987)
" for 2 weeks, was studied in a randomized, double-blind, crossover trial in nine patients with asthma receiving theophylline."5.06Effect of nifedipine and theophylline in asthma. ( Cohen, E; Garty, M; Ilfeld, DN; Mazar, A; Rosenfeld, JB; Spitzer, S, 1986)
"In order to evaluate the effect of nifedipine, a calcium channel blocker, upon specific bronchial responses to isocyanates, 5 subjects with occupational asthma due to TDI were examined."5.05Protective effect of nifedipine upon specific bronchial responses to isocyanates. ( Biscaldi, G; Candura, F; Gherson, G; Moscato, G, 1983)
"In 11 patients with bronchial asthma and regular overnight falls in PEFR of greater than 15%, we demonstrated significant bronchodilation restricted only to large airways after the administration of a single dose of 10 mg of nifedipine."5.05Nifedipine in bronchial asthma. ( Argiropoulou, P; Louridas, G; Patakas, D; Tsara, V; Vlachoianni, E, 1983)
"The effect of nifedipine (20 mg sublingually) on the bronchial response to cold air was studied in eight asthmatic patients and eight normal subjects."5.05Effect of nifedipine on bronchoconstriction induced by inhalation of cold air. ( Costello, JF; Heaton, RW; Henderson, AF, 1983)
"Seven asthmatic patients were studied in a single-blind randomized, crossover study after oral administration of 20 mg nifedipine or placebo."5.05Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline. ( Löfdahl, CG; Svedmyr, K; Svedmyr, N, 1984)
"The nifedipine effect was studied in 8 extrinsic asthmatic subjects with exercise-induced asthma."5.05Effect of a calcium antagonist, nifedipine, in exercise-induced asthma. ( Crimi, N; Gibellino, F; Mistretta, A; Palermo, F; Sorace, R, 1984)
"Calcium-channel blockers such as verapamil and nifedipine have been shown to inhibit exercise-induced asthma as well as acutely induced bronchoconstriction, but little is known of their chronic effects, if any, on bronchial asthma."5.05Nifedipine in chronic bronchial asthma: a randomized double-blind crossover trial against placebo. ( Boismare, F; Lemercier, JP; Leprevost, A; Moore, ND; Ozenne, G; Pasquis, P; Tardif, C, 1985)
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo."5.05Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983)
"We have administered nifedipine by aerosol to six patients with mild asthma to determine whether local administration of a potent calcium channel blocker has any effect on resting airway tone or histamine reactivity."5.05The effect of inhaled nifedipine on bronchial reactivity to histamine in man. ( Barnes, PJ; Cuss, FM, 1985)
"Nifedipine and verapamil have been shown to inhibit the bronchoconstriction provoked by exercise, histamine, methacholine and antigen."3.75Calcium-channel blockers in prophylaxis and treatment of asthma. ( Fanta, CH, 1985)
"RWJ 22108 (N-benzyl-N-methylaminoethyl 9-(2-chloro-6-fluorophenyl)-2,3,4,5,6,9-hexahydro-7-methyl-1, 1-dioxothiacyclohepteno-[3,2-b]pyridine-8-carboxylate) is a new bronchoselective calcium entry blocker with potential use as an antiasthmatic agent."3.68Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker. ( Ahmed, T; Anderson, DW; Capetola, RJ; Dodd, JH; Kirchner, T; Moore, JB; Ritchie, DM, 1993)
"Bronchial responsiveness to methacholine was studied in 23 stable asthmatics before and after nifedipine and diltiazem."3.68Effect of calcium channel antagonists on cholinergic bronchial responsiveness in asthma. ( Jindal, SK; Talwar, D, 1993)
"A study was made of the impact of a single intake of nifedipine, intal, sodium thiosulfate and essentiale on respiratory function, the blood content of ionized calcium, total calcium, hydroperoxides, total and non-protein thiol groups, and prostaglandins in bronchial asthma patients."3.68[The effect of a single dose of nifedipine, intal, sodium thiosulfate and Essentiale on the blood level of calcium, hydroperoxides, thiol compounds and prostaglandins in bronchial asthma patients]. ( Amatuni, VG; Malaian, KL; Zakaharian, AK, 1992)
"The protective effect of the calcium antagonist nifedipine (20 mg sublingually) on methacholine-induced bronchospasms was investigated in 14 mild asthmatics, 8 extrinsic and 6 intrinsic, in stable situations and with FEV1 greater than or equal to 80% of the one predicted."3.67Nifedipine decreases sensitivity and reactivity to methacholine in mild asthmatics. ( Marco, V; Pellicer, C; Perpiñá, M, 1987)
"Marked improvement in the respiratory status of two patients with chronic obstructive lung disease was observed during treatment with nifedipine for angina pectoris."3.67Exacerbation of asthmatic symptoms after cessation of nifedipine therapy. ( Eliraz, A; Fink, A; Wishnitzer, R, 1984)
"The inhibitory effect of nicardipine, a calcium antagonist, on the antigen- and anti-IgE-induced histamine release from basophilic leucocytes of patients with bronchial asthma was examined."3.67The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics. ( Kimura, I; Kitani, H; Komagoe, H; Maeda, M; Morinaga, H; Nakagawa, S; Ohtani, J; Takahashi, K; Tanizaki, Y, 1985)
"This prospective study was undertaken to evaluate the safety of nifedipine, a calcium channel blocking agent, on 60 subjects with asthma, chronic obstructive pulmonary disease (COPD), angina, and normal subjects."3.67Safety of nifedipine in subjects with bronchial asthma and COPD. ( Bewtra, A; Nair, CK; Nair, N; Townley, RG, 1984)
"The combined effect of oral nifedipine and aerosolized sodium cromoglycate on the airway response to inhaled sodium chloride at increasing concentrations was randomly studied in 10 patients with bronchial asthma."3.67The combined effect of nifedipine and sodium cromoglycate on the airway response to inhaled hypertonic saline in patients with bronchial asthma. ( Ganem, R; Greif, J; Kivity, S; Topilsky, M, 1989)
"Ten male asthmatic volunteers each inhaled two puffs (200 micrograms) of salbutamol on two separate days 30 minutes after double blind oral administration of either 20 mg nifedipine or identical placebo."3.67Nifedipine enhances the bronchodilator effect of salbutamol. ( Corris, PA; Gibson, GJ; Lever, AM, 1984)
" To determine the clinical relevance of this potential interaction in patients with chronic asthma, we measured a peak steady-state theophylline serum concentration in 21 subjects while receiving theophylline alone (400 to 1,500 mg/day), and again, at least seven days later, after the addition of continuous therapy with maximally tolerated doses of either diltiazem (n = 18) or nifedipine (n = 16)."3.67Clinical relevance of the interaction of theophylline with diltiazem or nifedipine. ( Christopher, MA; Harman, E; Hendeles, L, 1989)
" Certain drugs such as antihistamines and ketotifen may be more effective administered by inhalation since high concentrations with reduced unwanted effects can be achieved on the bronchial surface where, in allergic asthma, the critical initial interaction between sensitized mast cells (mucosal?) and allergen with subsequent mediator release occurs."3.67Use of inhaled calcium channel blocking agents in the treatment of asthma. ( Bennett, J; Davies, RJ; Osman, J, 1984)
"A study of patients with a stable course of bronchial asthma (BA) has confirmed the absence of a significant bronchodilating effect of nifedipine during an acute drug test (a single sublingual administration of the drug at a dose of 20 mg)."3.67[The possibilities and prospects in using the calcium antagonist korinfar in patients with bronchial asthma]. ( Alekseev, VG; Efimov, AV; Sinopal'nikov, AI, 1988)
"The induction of allergic pulmonary distress (APD) in ovalbumin sensitive rats can be used as a model of human allergic asthma."3.67The effect of calcium antagonists on allergic pulmonary distress in actively sensitized rats. ( Aspinall, RL; Carnathan, GW; Korach, ES, 1987)
" In order to evaluate whether nifedipine, a calcium channel blocking drug, could alter the bronchial reactivity to methacholine, nine patients suffering from occupational asthma were submitted to bronchial challenge with methacholine with and without premedication with nifedipine, 20 mg sublingually."3.67Effect of nifedipine on hyperreactive bronchial responses to methacholine. ( Candura, F; Danna, P; Dellabianca, A; Dorigo, N; Moscato, G, 1986)
"Long-acting nifedipine tablets were given to 47 severely and moderately hypertensive patients with renal insufficiency, cardiovascular, cerebrovascular, and peripheral vascular disease, diabetes mellitus, asthma, and systemic lupus erythematosus."3.67Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases. ( Bursztyn, M; Grossman, E; Rosenthal, T, 1985)
" The pharmacologic characteristics of the antigen-induced airway smooth muscle contraction in vitro were similar to those induced by arachidonic acid and the leukotrienes only in some respects but were clearly different from those induced by compound 48/80."3.67Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs. ( Davis, C; Kannan, L; Kannan, MS; Ladenius, AR; Sankaranarayanan, A, 1986)
"In the asthmatic model mainly mediated by the endogenous slow reacting substance of anaphylaxis (SRS-A) induced by the antigen inhalation to passively sensitized guinea pigs, continuous intravenous infusion of nifedipine (Adalat) at a speed of 7 micrograms/kg/min depressed the airway open pressure by about 68% compared to the saline-treated group and produced a delay in the time to peak response."3.67Effect of a Ca2+ antagonist, nifedipine, on the experimental asthma mediated mainly by slow reacting substance of anaphylaxis. ( Fujimura, M; Ishizaki, T; Kanamori, K; Koshino, T; Matsuda, T; Minami, S; Miyabo, S; Nishioka, S; Okafuji, K; Saga, T, 1985)
" 4 mg) and sub-lingual nifedipine (20 mg) against allergen-induced asthma were each assessed by the administration of calcium antagonists 30 min before bronchial provocation tests using Dermatophagoides pteronyssinus extracts on eight young perennial asthmatics."3.66Effect of calcium antagonists on allergen-induced asthma. ( Lam, WK; So, SY; Yu, DY, 1982)
"The effect of nifedipine was studied in fifteen patients with exercise-induced asthma."3.66The effect of calcium antagonist, nifedipine in exercise-induced asthma. ( Patel, KR, 1981)
"When diltiazem was given alone, it had no effect on the airway but, when given with nifedipine, it significantly raised the PC20 to methacholine."2.67Combined effect of nifedipine and diltiazem on methacholine-induced bronchoconstriction in asthmatic patients. ( Brayer, M; Kivity, S; Topilsky, M, 1992)
"Pretreatment with nifedipine significantly attenuated acetylcholine-induced changes in all four lung function parameters studied, but did not significantly influence the increase in thromboxane B2 plasma concentrations observed after the acetylcholine challenge."2.66Inhibition of acetylcholine-induced bronchoconstriction in asthmatics by nifedipine. ( Burghuber, OC; Haber, P; Harmuth, P; Kneussl, M; Silberbauer, K; Sinzinger, H, 1986)
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma."2.65A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981)
"High-altitude pulmonary edema is a non-cardiac edema that often precedes acute mountain sickness."2.42[Visiting high altitudes--healthy persons and patients with risk diseases]. ( Fischer, R, 2004)
"In 46 bronchial asthma (BA) patients, a study was made of the effects of calcium antagonists (CA) (corinfar, perdipine) on bronchial sensitivity and reactivity determined on bronchospasm induction with the increasing doses of acetylcholine."1.28[The clinico-functional effectiveness of calcium antagonists in correcting the bronchial hyperreactivity of bronchial asthma patients]. ( Fedoseev, GB; Shchemelinina, TI; Sinitsina, TM, 1990)

Research

Studies (103)

TimeframeStudies, this research(%)All Research%
pre-199089 (86.41)18.7374
1990's10 (9.71)18.2507
2000's3 (2.91)29.6817
2010's1 (0.97)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baraldi, PG1
Preti, D1
Materazzi, S1
Geppetti, P1
Fischer, R1
Townley, RG2
Moscato, G2
Gherson, G1
Biscaldi, G1
Candura, F2
Rolla, G1
Bucca, C1
Polizzi, S1
Maina, A1
Giachino, O1
Salvini, P1
Henderson, AF5
Heaton, RW3
Dunlop, LS3
Costello, JF5
Mohorn, M2
Knüpfer, M2
Patakas, D2
Vlachoianni, E1
Tsara, V2
Louridas, G1
Argiropoulou, P1
Corris, PA2
Nariman, S1
Gibson, GJ2
Svedmyr, K1
Löfdahl, CG1
Svedmyr, N1
Solway, J1
Quiret, JC1
Gillet, JC1
Rey, JL1
Lombaert, M1
Bernasconi, P1
Crimi, N2
Palermo, F2
Sorace, R1
Gibellino, F1
Mistretta, A2
Davies, RJ1
Bennett, J1
Osman, J1
Lever, AM1
Nair, N1
Bewtra, A1
Nair, CK1
Fish, JE1
Eliraz, A2
Wishnitzer, R1
Fink, A2
Koshino, T3
Tomioka, S2
Tochigi, T1
Arai, M2
Inazawa, M1
Fueki, R2
Kobayashi, S2
Williams, DO1
Barnes, PJ3
Vickers, HP1
Rudolf, M1
Patel, KR3
Al-Shamma, M1
Brugman, TM1
Darnell, ML1
Hirshman, CA1
Wilson, NM1
Brown, MJ1
Kerr, JW1
So, SY2
Lam, WK2
Yu, DY1
Cerrina, J1
Denjean, A1
Alexandre, G1
Lockhart, A1
Duroux, P1
Talwar, D1
Jindal, SK1
Gupta, S1
Meena, HS1
Chopra, R1
Bidani, R1
Ritchie, DM1
Kirchner, T1
Moore, JB1
Dodd, JH1
Ahmed, T2
Anderson, DW1
Capetola, RJ1
Small, RC1
Chiu, P1
Cook, SJ1
Foster, RW1
Isaac, L1
Tanaka, H1
Teramoto, S1
Oashi, K1
Saikai, T1
Tanaka, S1
Suzuki, K1
Hashimoto, M1
Abe, S1
Ann Twiss, M1
Harman, E2
Chesrown, S1
Hendeles, L2
Amatuni, VG1
Malaian, KL1
Zakaharian, AK1
Kivity, S2
Brayer, M1
Topilsky, M2
Pellegrino, R1
Violante, B1
Crimi, E1
Brusasco, V1
Yilmaz, E1
Canberk, A1
Eroğlu, L1
Tsuda, T1
Takeuchi, M1
Ishikawa, K1
Ando, H1
Hanamura, Y1
Takasu, H1
Fedoseev, GB1
Sinitsina, TM1
Shchemelinina, TI1
Abraham, WM1
Tanizaki, Y2
Komagoe, H2
Morinaga, H1
Ohtani, J2
Nakagawa, S1
Maeda, M1
Kitani, H2
Takahashi, K3
Kimura, I2
Sudo, M1
Tada, S1
Ip, M1
Vancheri, C1
Oliveri, R1
Distefano, SM1
Polosa, R1
Ganem, R1
Greif, J1
Palombo, C1
Mian, M1
Bertelli, A1
Middleton, E1
Ferrari, M1
Olivieri, M1
De Gasperi, M1
Lechi, A1
al-Waili, NS1
Marthan, R1
Woolcock, AJ1
Alekseev, VG2
Sinopal'nikov, AI2
Efimov, AV2
Zhang, XL1
Smith, SB1
Christopher, MA1
Delnitz, D1
Rozniecki, J1
Sharma, SK2
Pande, JN2
Guleria, JS2
Barliński, J1
Droszcz, W1
Wrońska, J1
Kannan, MS1
Davis, C1
Sankaranarayanan, A1
Ladenius, AR1
Kannan, L1
Kolomiets, VV1
Liashevskaia, TN1
Tomash, OV1
Molchanov, OL1
Vasilenko, VV1
Wasek, Z1
Lidji, M1
Molho, M2
Chagnac, A1
Katz, I2
Benzaray, S1
Maniki, E1
Dascalopoulou, E1
Smith, SR1
Wiggins, J1
Stableforth, DE1
Skinner, C1
Kendall, MJ1
Gordon, EH1
Wong, SC1
Klaustermeyer, WB1
Fujiwara, T1
Itoh, T1
Kuriyama, H1
Korach, ES1
Carnathan, GW1
Aspinall, RL1
Larach, DR1
Zelis, R1
Olive, SR1
Hansen, JE2
Sue, DY2
Ben-Dov, I2
Wasserman, K2
Kardaszewicz, B1
Danek, K1
Ballester, E1
Roca, J1
Rodriguez-Roisin, R1
Agusti-Vidal, A1
Perpiñá, M1
Pellicer, C1
Marco, V1
Gruzman, C1
Lidgi, M1
Chaniac, A1
Rafferty, P1
Varley, JG1
Edwards, JS1
Holgate, ST1
Garty, M1
Cohen, E1
Mazar, A1
Ilfeld, DN1
Spitzer, S1
Rosenfeld, JB1
Schwartzstein, RS1
Fanta, CH2
Sun, B1
Spedini, C1
Lombardi, C1
Kuroiwa, H1
Burghuber, OC1
Kneussl, M1
Harmuth, P1
Silberbauer, K1
Sinzinger, H1
Haber, P1
Toldi, Z1
Gyurkovits, K1
Ozenne, G1
Moore, ND1
Leprevost, A1
Tardif, C1
Boismare, F1
Pasquis, P1
Lemercier, JP1
Magnussen, H1
Bibi, H1
Tabachnik, E1
Bentwich, Z1
Danna, P1
Dorigo, N1
Dellabianca, A1
Bursztyn, M1
Grossman, E1
Rosenthal, T1
Rotrekl, P1
Lupínek, Z1
Cermáková, E1
Ohnútková, E1
Fujimura, M2
Nishioka, S2
Okafuji, K2
Minami, S2
Kanamori, K2
Matsuda, T2
Ishizaki, T2
Saga, T2
Miyabo, S2
Ikeda, H1
Sasaki, H1
Ito, E1
Yasui, S1
White, SR1
Hall, JB1
Cuss, FM1

Reviews

9 reviews available for nifedipine and Asthma

ArticleYear
Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.
    Journal of medicinal chemistry, 2010, Jul-22, Volume: 53, Issue:14

    Topics: Analgesics; Animals; Anti-Inflammatory Agents; Asthma; Humans; Ion Channel Gating; Neurons; Pain; Pe

2010
[Visiting high altitudes--healthy persons and patients with risk diseases].
    MMW Fortschritte der Medizin, 2004, Feb-19, Volume: 146, Issue:8

    Topics: Acclimatization; Acetazolamide; Acute Disease; Altitude; Altitude Sickness; Anti-Inflammatory Agents

2004
Role of calcium-channel blockers in obstructive airway disease.
    Chest, 1985, Volume: 88, Issue:2 Suppl

    Topics: Acetylcholine; Animals; Asthma; Asthma, Exercise-Induced; Calcium; Calcium Channel Blockers; Diltiaz

1985
Calcium channel blockers and asthma.
    Lung, 1986, Volume: 164, Issue:1

    Topics: Animals; Asthma; Bronchi; Bronchodilator Agents; Calcium; Calcium Channel Blockers; Cell Adhesion; C

1986
[Calcium antagonists: accounts on new perspectives of their use and an update on side effects].
    La Clinica terapeutica, 1989, Feb-15, Volume: 128, Issue:3

    Topics: Adult; Animals; Asthma; Calcium Channel Blockers; Cardiovascular Diseases; Diltiazem; Esophageal Ach

1989
Newer drugs in management. Calcium antagonists.
    Chest, 1985, Volume: 87, Issue:1 Suppl

    Topics: Animals; Asthma; Calcium; Calcium Channel Blockers; Guinea Pigs; Histamine Release; Humans; Ion Chan

1985
Advances in calcium blocker therapy.
    American journal of surgery, 1986, Volume: 151, Issue:4

    Topics: Arrhythmias, Cardiac; Arteriosclerosis; Asthma; Blood Platelet Disorders; Calcium; Calcium Channel B

1986
[Use of calcium antagonists in the treatment of bronchial asthma].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:2

    Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Bronchodilator Agents; Clinical Trials as Topic; Drug Eva

1986
Calcium-channel blockers in prophylaxis and treatment of asthma.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Antigens; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Bronchodi

1985

Trials

48 trials available for nifedipine and Asthma

ArticleYear
Protective effect of nifedipine upon specific bronchial responses to isocyanates.
    Giornale italiano di medicina del lavoro, 1983, Volume: 5, Issue:6

    Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Constriction, Patholo

1983
Nifedipine inhibits deep-inspiration-induced bronchoconstriction in asthmatics.
    Lancet (London, England), 1982, Jun-05, Volume: 1, Issue:8284

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Clinical Trials as Topic; Constriction, Patho

1982
The effect of nifedipine on antigen-induced bronchoconstriction.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Adult; Antigens; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expiratory Vo

1983
Nifedipine in bronchial asthma.
    The Journal of allergy and clinical immunology, 1983, Volume: 72, Issue:3

    Topics: Adult; Aged; Airway Resistance; Asthma; Circadian Rhythm; Clinical Trials as Topic; Drug Administrat

1983
Effect of nifedipine on bronchoconstriction induced by inhalation of cold air.
    Thorax, 1983, Volume: 38, Issue:7

    Topics: Adult; Airway Resistance; Asthma; Bronchi; Bronchial Provocation Tests; Clinical Trials as Topic; Co

1983
Nifedipine in the prevention of asthma induced by exercise and histamine.
    The American review of respiratory disease, 1983, Volume: 128, Issue:6

    Topics: Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory V

1983
Nifedipine--a calcium channel blocker--in asthmatic patients. Interaction with terbutaline.
    Allergy, 1984, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Aged; Asthma; Blood Pressure; Calcium Channel Blockers; Clinical Trials

1984
[Propranolol-nifedipine combination in the treatment of exercise-induced asthma].
    Archives des maladies du coeur et des vaisseaux, 1983, Volume: 76, Issue:10

    Topics: Asthma; Asthma, Exercise-Induced; Drug Therapy, Combination; Drug Tolerance; Exercise Test; Humans;

1983
Effect of a calcium antagonist, nifedipine, in exercise-induced asthma.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Doub

1984
[The effect of calcium-antagonist on bronchoconstriction in asthmatics].
    Arerugi = [Allergy], 1982, Volume: 31, Issue:12

    Topics: Adult; Aged; Asthma; Bronchi; Calcium Channel Blockers; Clinical Trials as Topic; Double-Blind Metho

1982
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.
    British medical journal (Clinical research ed.), 1981, Aug-01, Volume: 283, Issue:6287

    Topics: Adult; Asthma; Bronchial Provocation Tests; Histamine; Humans; Middle Aged; Nifedipine; Pyridines; R

1981
Effect of nifedipine on histamine reactivity in asthma.
    British medical journal (Clinical research ed.), 1982, Jun-26, Volume: 284, Issue:6333

    Topics: Adolescent; Adult; Asthma; Bronchi; Double-Blind Method; Female; Forced Expiratory Volume; Histamine

1982
A calcium antagonist, nifedipine, modifies exercise-induced asthma.
    Thorax, 1981, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl

1981
Inhibition of exercise-induced asthma by a calcium antagonist, nifedipine.
    The American review of respiratory disease, 1981, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Calcium; Female; Humans; Lung Volume Measuremen

1981
Effect of aerosolised verapamil and nifedipine in bronchial asthma.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:7

    Topics: Administration, Inhalation; Adult; Aerosols; Asthma; Female; Humans; Nifedipine; Verapamil

1993
Effects of candesartan on cough and bronchial hyperresponsiveness in mildly to moderately hypertensive patients with symptomatic asthma.
    Circulation, 2001, Jul-17, Volume: 104, Issue:3

    Topics: Adult; Aged; Antihypertensive Agents; Asthma; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Br

2001
Efficacy of calcium channel blockers as maintenance therapy for asthma.
    British journal of clinical pharmacology, 2002, Volume: 53, Issue:3

    Topics: Adolescent; Adult; Asthma; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Double-Blind Met

2002
Combined effect of nifedipine and diltiazem on methacholine-induced bronchoconstriction in asthmatic patients.
    Annals of allergy, 1992, Volume: 68, Issue:2

    Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Diltiazem; Drug Therapy

1992
Time course and calcium dependence of sustained bronchoconstriction induced by deep inhalation in asthma.
    The American review of respiratory disease, 1991, Volume: 144, Issue:6

    Topics: Adult; Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Calcium;

1991
Nifedipine alters serum theophylline levels in asthmatic patients with hypertension.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:4

    Topics: Adult; Asthma; Blood Pressure; Double-Blind Method; Drug Interactions; Female; Humans; Hypertension;

1991
Effect of sodium cromoglycate and nifedipine on adenosine-induced bronchoconstriction.
    Respiration; international review of thoracic diseases, 1988, Volume: 53, Issue:2

    Topics: Adenosine; Adult; Asthma; Bronchial Spasm; Calcium; Cromolyn Sodium; Double-Blind Method; Female; Hu

1988
Differential effects of nifedipine and diltiazem on methacholine-induced bronchospasm in allergic asthma.
    Annals of allergy, 1989, Volume: 63, Issue:3

    Topics: Adult; Asthma; Blood Pressure; Bronchial Provocation Tests; Bronchial Spasm; Clinical Trials as Topi

1989
Nifedipine in corticosteroid-dependent asthma: preliminary study.
    Clinical and experimental pharmacology & physiology, 1989, Volume: 16, Issue:9

    Topics: Adrenal Cortex Hormones; Adult; Aged; Asthma; Blood Pressure; Double-Blind Method; Female; Heart Rat

1989
Is a myogenic response involved in deep inspiration-induced bronchoconstriction in asthmatics?
    The American review of respiratory disease, 1989, Volume: 140, Issue:5

    Topics: Airway Resistance; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Humans; Methacholine Chlori

1989
[Effects of nifedipine on pollen-antigen-induced bronchoconstriction in asthmatics].
    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases, 1989, Volume: 12, Issue:3

    Topics: Adult; Asthma; Double-Blind Method; Female; Humans; Male; Middle Aged; Nifedipine; Pollen; Random Al

1989
[Pharmacological prevention of exercise-induced bronchospasm in patients with asthma].
    Pneumonologia polska, 1985, Volume: 53, Issue:4

    Topics: Adult; Aerosols; Albuterol; Aminophylline; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents;

1985
Nifedipine and pulmonary functions in bronchial asthma.
    The Journal of the Association of Physicians of India, 1988, Volume: 36, Issue:5

    Topics: Administration, Sublingual; Adolescent; Adult; Airway Resistance; Asthma; Clinical Trials as Topic;

1988
The effect of nifedipine on bronchial reactivity to inhaled histamine and methacholine: a comparative study in normal and asthmatic subjects.
    British journal of diseases of the chest, 1988, Volume: 82, Issue:4

    Topics: Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Female; Forced Expiratory Volume; His

1988
Therapy with nifedipine in asthma: a randomized double-blind crossover trial.
    Israel journal of medical sciences, 1988, Volume: 24, Issue:1

    Topics: Adult; Asthma; Clinical Trials as Topic; Double-Blind Method; Humans; Male; Nifedipine; Random Alloc

1988
Nifedipine treatment of patients with bronchial asthma.
    The Journal of allergy and clinical immunology, 1987, Volume: 79, Issue:6

    Topics: Adult; Aged; Albuterol; Asthma; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Double-B

1987
Effect of nifedipine on serum theophylline concentrations and asthma control.
    Thorax, 1987, Volume: 42, Issue:10

    Topics: Aged; Asthma; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Huma

1987
Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1987, Volume: 24, Issue:5

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Calcium Channel Blockers; Clinical Trials as Topic; Double-

1987
Comparison of PY 108-068, a new calcium antagonist, with nifedipine in exercise-induced asthma.
    Chest, 1986, Volume: 90, Issue:2

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Calcium Channel Blockers; Clinical Tri

1986
[Use of calcium antagonists in the treatment of bronchial asthma].
    Polskie Archiwum Medycyny Wewnetrznej, 1986, Volume: 75, Issue:2

    Topics: Animals; Asthma; Bronchi; Bronchial Spasm; Bronchodilator Agents; Clinical Trials as Topic; Drug Eva

1986
Effect of nifedipine on arterial hypoxaemia occurring after methacholine challenge in asthma.
    Thorax, 1986, Volume: 41, Issue:6

    Topics: Adult; Airway Resistance; Asthma; Clinical Trials as Topic; Double-Blind Method; Female; Forced Expi

1986
Nifedipine in asthma. Dose-related effect on resting bronchial tone.
    Chest, 1987, Volume: 91, Issue:5

    Topics: Adolescent; Adult; Albuterol; Asthma; Bronchi; Clinical Trials as Topic; Dose-Response Relationship,

1987
Inhibition of exercise-induced asthma by nifedipine: a dose-response study.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:4

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Dose-Response Relationship, Drug; Female; Forced Expiratory

1987
Effect of nifedipine and theophylline in asthma.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:2

    Topics: Adult; Aged; Animals; Asthma; Double-Blind Method; Drug Evaluation; Drug Interactions; Humans; Kinet

1986
Orally administered nifedipine in chronic stable asthma. Comparison with an orally administered sympathomimetic.
    The American review of respiratory disease, 1986, Volume: 134, Issue:2

    Topics: Administration, Oral; Adult; Albuterol; Asthma; Double-Blind Method; Female; Forced Expiratory Volum

1986
The effect of nifedipine on exercise-induced asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1986, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Double-Blind Method; Drug Evaluation; Female; H

1986
Long-term treatment with oral nifedipine plus theophylline in the management of chronic bronchial asthma.
    European journal of clinical pharmacology, 1986, Volume: 31, Issue:1

    Topics: Aged; Asthma; Chronic Disease; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nifedip

1986
Effect of nifedipine on dose-response curves to acetylcholine and histamine measured during quiet breathing.
    Respiration; international review of thoracic diseases, 1986, Volume: 50, Issue:3

    Topics: Acetylcholine; Adult; Aged; Asthma; Bronchial Provocation Tests; Bronchial Spasm; Dose-Response Rela

1986
Inhibition of acetylcholine-induced bronchoconstriction in asthmatics by nifedipine.
    Respiration; international review of thoracic diseases, 1986, Volume: 50, Issue:4

    Topics: Acetylcholine; Adult; Airway Resistance; Asthma; Bronchial Provocation Tests; Double-Blind Method; F

1986
Calcium-channel blockers in prophylaxis and treatment of asthma.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Antigens; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Bronchodi

1985
[Effect of corinfar on histamine- or acetylcholine-induced bronchial spasm].
    Orvosi hetilap, 1985, May-26, Volume: 126, Issue:21

    Topics: Acetylcholine; Adolescent; Asthma; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Child; Chi

1985
Nifedipine in chronic bronchial asthma: a randomized double-blind crossover trial against placebo.
    European journal of respiratory diseases, 1985, Volume: 67, Issue:4

    Topics: Adolescent; Adult; Albuterol; Asthma; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Dou

1985
Bronchodilatation and attenuation of exercise-induced bronchospasm by PY 108-068, a new calcium antagonist.
    The American review of respiratory disease, 1986, Volume: 133, Issue:1

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Calcium Channel Blockers; Female; Fo

1986
The effect of inhaled nifedipine on bronchial reactivity to histamine in man.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:5

    Topics: Adult; Aerosols; Asthma; Blood Pressure; Bronchi; Bronchial Provocation Tests; Bronchial Spasm; Fema

1985

Other Studies

48 other studies available for nifedipine and Asthma

ArticleYear
Role of calcium channel blocking agents in the treatment of allergic asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Animals; Asthma; Basophils; Bronchial Provocation Tests; Bronchial Spasm; Calcium; Calcium Channel B

1984
Effects of nifedipine on antigen-induced bronchoconstriction.
    The American review of respiratory disease, 1983, Volume: 127, Issue:5

    Topics: Adult; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Calcium Channel Blockers; Dose-Respons

1983
[Effectiveness of the calcium antagonist nifedipine and the protease inhibitor with plasmin inactivating effect para-aminomethylbenzoic acid on stress-induced bronchial asthma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Nov-01, Volume: 39, Issue:21

    Topics: 4-Aminobenzoic Acid; Adolescent; Adult; Airway Resistance; Aminobenzoates; Antifibrinolytic Agents;

1984
Calcium channel blocking agents in bronchial hyperreactivity.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; C

1984
Use of inhaled calcium channel blocking agents in the treatment of asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Aerosols; Airway Resistance; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Test

1984
Nifedipine enhances the bronchodilator effect of salbutamol.
    Thorax, 1984, Volume: 39, Issue:8

    Topics: Adult; Albuterol; Asthma; Double-Blind Method; Drug Synergism; Forced Expiratory Volume; Humans; Mal

1984
Safety of nifedipine in subjects with bronchial asthma and COPD.
    Chest, 1984, Volume: 86, Issue:4

    Topics: Adult; Aged; Angina Pectoris; Asthma; Female; Forced Expiratory Flow Rates; Forced Expiratory Volume

1984
Calcium channel antagonists in the treatment of asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Airway Resistance; Animals; Asthma; Biological Transport; Calcium; Calcium Channel Blockers; Diltiaz

1984
In vitro effects of nifedipine on airways smooth muscle.
    Agents and actions. Supplements, 1983, Volume: 13

    Topics: Animals; Asthma; Bronchi; Guinea Pigs; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smoo

1983
Calcium channel blocking agents. Council on scientific affairs.
    JAMA, 1983, Nov-11, Volume: 250, Issue:18

    Topics: Angina Pectoris; Animals; Arrhythmias, Cardiac; Asthma; Calcium Channel Blockers; Cardiomyopathy, Hy

1983
Exacerbation of asthmatic symptoms after cessation of nifedipine therapy.
    Annals of allergy, 1984, Volume: 52, Issue:2

    Topics: Aged; Angina Pectoris; Asthma; Bronchodilator Agents; Humans; Male; Middle Aged; Nifedipine

1984
[The effects of Ca++ antagonists nifedipine and nicardipine on slow reacting substance of anaphylaxis (SRS-A) mediated bronchoconstriction in guinea pig].
    Arerugi = [Allergy], 1984, Volume: 33, Issue:1

    Topics: Animals; Asthma; Calcium Channel Blockers; Depression, Chemical; Guinea Pigs; Male; Mast Cells; Nica

1984
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.
    British medical journal (Clinical research ed.), 1981, Sep-19, Volume: 283, Issue:6294

    Topics: Asthma; Asthma, Exercise-Induced; Blood Pressure; Humans; Nifedipine; Pyridines

1981
Nifedipine aerosol attenuates airway constriction in dogs with hyperreactive airways.
    The American review of respiratory disease, 1983, Volume: 127, Issue:1

    Topics: Aerosols; Airway Resistance; Animals; Asthma; Bronchi; Bronchial Provocation Tests; Constriction, Pa

1983
Calcium antagonists in experimental asthma.
    Clinical allergy, 1982, Volume: 12 Suppl

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl

1982
Effect of calcium antagonists on allergen-induced asthma.
    Clinical allergy, 1982, Volume: 12, Issue:6

    Topics: Adolescent; Allergens; Asthma; Bronchial Provocation Tests; Calcium Channel Blockers; Forced Expirat

1982
The effect of calcium antagonist, nifedipine in exercise-induced asthma.
    Clinical allergy, 1981, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Humans; Male;

1981
Effect of calcium channel antagonists on cholinergic bronchial responsiveness in asthma.
    The Journal of the Association of Physicians of India, 1993, Volume: 41, Issue:5

    Topics: Asthma; Bronchial Hyperreactivity; Bronchial Provocation Tests; Bronchoconstriction; Calcium Channel

1993
Experimental antiasthmatic activity of RWJ 22108: a bronchoselective calcium entry blocker.
    International archives of allergy and immunology, 1993, Volume: 100, Issue:3

    Topics: Airway Obstruction; Airway Resistance; Animals; Antigens; Asthma; Bronchial Spasm; Bronchoconstricti

1993
Beta-adrenoceptor agonists in bronchial asthma: role of k+-channel opening in mediating their bronchodilator effects.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1993, Volume: 23, Issue:10

    Topics: Adrenergic beta-1 Receptor Antagonists; Adrenergic beta-2 Receptor Antagonists; Adrenergic beta-Anta

1993
[The effect of a single dose of nifedipine, intal, sodium thiosulfate and Essentiale on the blood level of calcium, hydroperoxides, thiol compounds and prostaglandins in bronchial asthma patients].
    Terapevticheskii arkhiv, 1992, Volume: 64, Issue:3

    Topics: Antioxidants; Asthma; Calcium; Cromolyn Sodium; Drug Evaluation; Humans; Hydrogen Peroxide; Nifedipi

1992
Bronchodilating effect of inhaled or orally administered calcium channel blocking agents on methacholine-induced bronchoconstriction.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:4 Pt 2

    Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Airway Resistance; Asthma; Bron

1990
[The clinico-functional effectiveness of calcium antagonists in correcting the bronchial hyperreactivity of bronchial asthma patients].
    Terapevticheskii arkhiv, 1990, Volume: 62, Issue:1

    Topics: Acetylcholine; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Bronchodilator Agents; Calcium C

1990
The calcium antagonist, nicardipine, inhibits antigen-stimulated and anti-IgE-induced histamine release from basophilic leucocytes of atopic asthmatics.
    Acta medica Okayama, 1985, Volume: 39, Issue:4

    Topics: Antibodies, Anti-Idiotypic; Antigens; Asthma; Basophils; Calcium Channel Blockers; Histamine Release

1985
[Inhibition of a calcium antagonist, nicardipine, of histamine release from basophil leukocytes of patients with bronchial asthma].
    Nihon Kyobu Shikkan Gakkai zasshi, 1985, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Aged; Asthma; Basophils; Calcium Channel Blockers; Child; Depression, Chemical; F

1985
The combined effect of nifedipine and sodium cromoglycate on the airway response to inhaled hypertonic saline in patients with bronchial asthma.
    The European respiratory journal, 1989, Volume: 2, Issue:6

    Topics: Administration, Inhalation; Adult; Asthma; Bronchi; Bronchial Provocation Tests; Cromolyn Sodium; Dr

1989
[The effect of the calcium antagonist nifedipine on stress-induced bronchial asthma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Nov-15, Volume: 44, Issue:22

    Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Asthma, Exercise-Induced; Exercise Test; Female;

1989
[Use of calcium antagonists in therapy of bronchial asthma].
    Terapevticheskii arkhiv, 1989, Volume: 61, Issue:3

    Topics: Asthma; Calcium Channel Blockers; Drug Synergism; Humans; Nifedipine; Sympathomimetics; Verapamil

1989
Exercise-induced asthma. Diagnostic clues with recommendation for treatment.
    Postgraduate medicine, 1985, Volume: 77, Issue:8

    Topics: Adrenergic beta-Agonists; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Cromolyn Sodium; Forced

1985
Clinical relevance of the interaction of theophylline with diltiazem or nifedipine.
    Chest, 1989, Volume: 95, Issue:2

    Topics: Adolescent; Adult; Asthma; Diltiazem; Drug Interactions; Drug Therapy, Combination; Humans; Nifedipi

1989
[Protective effect of nifedipine on histamine-induced bronchial spasm in patients responding and not responding to Intal treatment].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Jul-15, Volume: 39, Issue:14

    Topics: Adult; Asthma; Bronchial Spasm; Cromolyn Sodium; Female; Histamine; Humans; Male; Nifedipine

1986
Pharmacological characterization of airway smooth muscle responses to antigen in ascaris-sensitive dogs.
    Canadian journal of physiology and pharmacology, 1986, Volume: 64, Issue:11

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Airway Resistance; Animals; Antigens, Helminth; Arac

1986
[Use of nifedipine in the broncho-obstructive syndrome].
    Vrachebnoe delo, 1988, Issue:11

    Topics: Administration, Sublingual; Asthma; Bronchitis; Bronchodilator Agents; Chronic Disease; Drug Evaluat

1988
[Calcium channel blockers and their value in the treatment of bronchial asthma].
    Pneumonologia polska, 1988, Volume: 56, Issue:10

    Topics: Asthma; Bronchi; Bronchodilator Agents; Diltiazem; Drug Evaluation; Humans; Nifedipine; Verapamil

1988
[The possibilities and prospects in using the calcium antagonist korinfar in patients with bronchial asthma].
    Terapevticheskii arkhiv, 1988, Volume: 60, Issue:3

    Topics: Administration, Inhalation; Aged; Albuterol; Asthma; Bronchial Provocation Tests; Calcium Channel Bl

1988
Regional differences in the mechanical properties of rabbit airway smooth muscle.
    British journal of pharmacology, 1988, Volume: 94, Issue:2

    Topics: Acetylcholine; Animals; Asthma; Bronchi; Histamine; In Vitro Techniques; Indomethacin; Male; Muscle

1988
The effect of calcium antagonists on allergic pulmonary distress in actively sensitized rats.
    Allergy, 1987, Volume: 42, Issue:8

    Topics: Administration, Oral; Aerosols; Animals; Asthma; Calcium Channel Blockers; Diltiazem; Female; Nifedi

1987
Nifedipine decreases sensitivity and reactivity to methacholine in mild asthmatics.
    Respiration; international review of thoracic diseases, 1987, Volume: 51, Issue:1

    Topics: Adolescent; Adult; Asthma; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Chloride;

1987
[Effects of nifedipine on bronchial hyperreactivity in asthmatics].
    Zhonghua jie he he hu xi xi ji bing za zhi = Chinese journal of tuberculosis and respiratory diseases, 1986, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Airway Resistance; Asthma; Bronchi; Female; Humans; Male; Middle Aged; Muscle Con

1986
[Treatment of chronic bronchial asthma].
    Der Internist, 1985, Volume: 26, Issue:4

    Topics: Asthma; Chronic Disease; Cromolyn Sodium; Glucocorticoids; Humans; Ketotifen; Male; Nifedipine; Para

1985
Leukotrienes (LTC4, LTD4) confer glass non-adherence on leukocytes of asthmatic individuals. Dependency on cyclooxygenase products and calcium ion.
    Immunology letters, 1985, Volume: 10, Issue:6

    Topics: Asthma; Calcium; Cell Adhesion; Child; Cyclooxygenase Inhibitors; Dinoprostone; Glass; Humans; Indom

1985
Effect of nifedipine on hyperreactive bronchial responses to methacholine.
    Annals of allergy, 1986, Volume: 56, Issue:2

    Topics: Adult; Asthma; Bronchi; Bronchial Provocation Tests; Female; Humans; Male; Methacholine Compounds; M

1986
Long-acting nifedipine in moderate and severe hypertensive patients with serious concomitant diseases.
    American heart journal, 1985, Volume: 110, Issue:1 Pt 1

    Topics: Adult; Aged; Angina Pectoris; Asthma; Cerebrovascular Disorders; Diabetes Complications; Edema; Fema

1985
[Is the administration of nifedipine to asthmatics without danger?].
    Vnitrni lekarstvi, 1985, Volume: 31, Issue:6

    Topics: Adult; Asthma; Female; Humans; Male; Middle Aged; Nifedipine

1985
Effects of Ca2+ antagonist, nicardipine, on experimental asthma with special reference to slow reacting substance of anaphylaxis.
    Allergy, 1985, Volume: 40, Issue:5

    Topics: Airway Resistance; Animals; Antigens; Asthma; Calcium Channel Blockers; Guinea Pigs; Male; Nicardipi

1985
Acute effects of nifedipine on patients with chronic obstructive lung disease.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:2

    Topics: Adult; Aged; Airway Resistance; Asthma; Blood Gas Analysis; Blood Pressure; Female; Forced Expirator

1985
Control of hypertension with nifedipine in the setting of aortic dissection.
    Chest, 1985, Volume: 88, Issue:5

    Topics: Aortic Aneurysm; Aortic Dissection; Asthma; Humans; Hypertension; Male; Middle Aged; Nifedipine

1985
Effect of a Ca2+ antagonist, nifedipine, on the experimental asthma mediated mainly by slow reacting substance of anaphylaxis.
    Arzneimittel-Forschung, 1985, Volume: 35, Issue:8

    Topics: Airway Resistance; Animals; Asthma; Blood Pressure; Disease Models, Animal; Guinea Pigs; Immunizatio

1985