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nifedipine and Asthma, Exercise-Induced

nifedipine has been researched along with Asthma, Exercise-Induced in 24 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Asthma, Exercise-Induced: Asthma attacks following a period of exercise. Usually the induced attack is short-lived and regresses spontaneously. The magnitude of postexertional airway obstruction is strongly influenced by the environment in which exercise is performed (i.e. inhalation of cold air during physical exertion markedly augments the severity of the airway obstruction; conversely, warm humid air blunts or abolishes it).

Research Excerpts

ExcerptRelevanceReference
"Four patients with documented exercise-induced asthma (EIA) were pretreated orally in random, double-blind fashion with the calcium channel blockers nifedipine 20 mg and flordipine 25 and 50 mg and placebo, then subjected to exercise challenge on a cycloergometer."9.06Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma. ( Gordon, EH; Klaustermeyer, WB; Wong, SC, 1987)
" The effect of three single doses of nifedipine on exercise-induced asthma has been examined in 11 asthmatic subjects."9.06Inhibition of exercise-induced asthma by nifedipine: a dose-response study. ( Edwards, JS; Holgate, ST; Rafferty, P; Varley, JG, 1987)
"This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA)."9.06The effect of nifedipine on exercise-induced asthma. ( Guleria, JS; Pande, JN; Sharma, SK, 1986)
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo."9.05Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983)
"The nifedipine effect was studied in 8 extrinsic asthmatic subjects with exercise-induced asthma."9.05Effect of a calcium antagonist, nifedipine, in exercise-induced asthma. ( Crimi, N; Gibellino, F; Mistretta, A; Palermo, F; Sorace, R, 1984)
"The effect of nifedipine was studied in fifteen patients with exercise-induced asthma."7.66The effect of calcium antagonist, nifedipine in exercise-induced asthma. ( Patel, KR, 1981)
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma."6.65A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981)
"Four patients with documented exercise-induced asthma (EIA) were pretreated orally in random, double-blind fashion with the calcium channel blockers nifedipine 20 mg and flordipine 25 and 50 mg and placebo, then subjected to exercise challenge on a cycloergometer."5.06Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma. ( Gordon, EH; Klaustermeyer, WB; Wong, SC, 1987)
" The effect of three single doses of nifedipine on exercise-induced asthma has been examined in 11 asthmatic subjects."5.06Inhibition of exercise-induced asthma by nifedipine: a dose-response study. ( Edwards, JS; Holgate, ST; Rafferty, P; Varley, JG, 1987)
"This article describes the effect of nifedipine, a calcium antagonist, on exercise-induced asthma (EIA)."5.06The effect of nifedipine on exercise-induced asthma. ( Guleria, JS; Pande, JN; Sharma, SK, 1986)
"Eight young men with documented exercise-induced asthma each performed two standard exercise tests and underwent two histamine challenges on separate days after double blind administration of either 20 mg nifedipine or placebo."5.05Nifedipine in the prevention of asthma induced by exercise and histamine. ( Corris, PA; Gibson, GJ; Nariman, S, 1983)
"The nifedipine effect was studied in 8 extrinsic asthmatic subjects with exercise-induced asthma."5.05Effect of a calcium antagonist, nifedipine, in exercise-induced asthma. ( Crimi, N; Gibellino, F; Mistretta, A; Palermo, F; Sorace, R, 1984)
"Nifedipine and verapamil have been shown to inhibit the bronchoconstriction provoked by exercise, histamine, methacholine and antigen."3.75Calcium-channel blockers in prophylaxis and treatment of asthma. ( Fanta, CH, 1985)
" Certain drugs such as antihistamines and ketotifen may be more effective administered by inhalation since high concentrations with reduced unwanted effects can be achieved on the bronchial surface where, in allergic asthma, the critical initial interaction between sensitized mast cells (mucosal?) and allergen with subsequent mediator release occurs."3.67Use of inhaled calcium channel blocking agents in the treatment of asthma. ( Bennett, J; Davies, RJ; Osman, J, 1984)
"The effect of nifedipine was studied in fifteen patients with exercise-induced asthma."3.66The effect of calcium antagonist, nifedipine in exercise-induced asthma. ( Patel, KR, 1981)
"Nifedipine was found to produce a more remarkable bronchodilatory effect."2.67[Asthma of physical effort and the effect of nifedipine and diltiazem]. ( Belonosov, SS; Chel'tsov, VV; Lepakhin, VK; Moiseev, VS; Rubtsova, II; Trufanova, LM, 1991)
"Nifedipine is a potent antagonist of calcium ion influx in smooth muscle and secretory cells, and these studies suggest that it may inhibit release of mast cell mediators and reduce bronchial smooth muscle contractility in asthma."2.65A calcium antagonist, nifedipine, modifies exercise-induced asthma. ( Barnes, PJ; Brown, MJ; Wilson, NM, 1981)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199023 (95.83)18.7374
1990's1 (4.17)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Townley, RG1
Mohorn, M2
Knüpfer, M2
Corris, PA1
Nariman, S1
Gibson, GJ1
Solway, J1
Quiret, JC1
Gillet, JC1
Rey, JL1
Lombaert, M1
Bernasconi, P1
Crimi, N1
Palermo, F1
Sorace, R1
Gibellino, F1
Mistretta, A1
Davies, RJ1
Bennett, J1
Osman, J1
Barnes, PJ1
Wilson, NM1
Brown, MJ1
Patel, KR2
Kerr, JW1
Cerrina, J1
Denjean, A1
Alexandre, G1
Lockhart, A1
Duroux, P1
Trufanova, LM1
Belonosov, SS1
Rubtsova, II1
Chel'tsov, VV1
Lepakhin, VK1
Moiseev, VS1
Ahmed, T1
Abraham, WM1
Berman, BA1
Ross, RN1
Smith, SB1
Delnitz, D1
Rozniecki, J1
Gordon, EH1
Wong, SC1
Klaustermeyer, WB1
Olive, SR1
Hansen, JE2
Sue, DY2
Ben-Dov, I2
Wasserman, K2
Rafferty, P1
Varley, JG1
Edwards, JS1
Holgate, ST1
Sharma, SK1
Pande, JN1
Guleria, JS1
Fanta, CH1

Reviews

3 reviews available for nifedipine and Asthma, Exercise-Induced

ArticleYear
Role of calcium-channel blockers in obstructive airway disease.
    Chest, 1985, Volume: 88, Issue:2 Suppl

    Topics: Acetylcholine; Animals; Asthma; Asthma, Exercise-Induced; Calcium; Calcium Channel Blockers; Diltiaz

1985
Treating coexisting cardiovascular and pulmonary disease with calcium antagonists.
    Annals of allergy, 1986, Volume: 56, Issue:3

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Ca

1986
Calcium-channel blockers in prophylaxis and treatment of asthma.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Antigens; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Bronchodi

1985

Trials

13 trials available for nifedipine and Asthma, Exercise-Induced

ArticleYear
Nifedipine in the prevention of asthma induced by exercise and histamine.
    The American review of respiratory disease, 1983, Volume: 128, Issue:6

    Topics: Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Double-Blind Method; Forced Expiratory V

1983
[Propranolol-nifedipine combination in the treatment of exercise-induced asthma].
    Archives des maladies du coeur et des vaisseaux, 1983, Volume: 76, Issue:10

    Topics: Asthma; Asthma, Exercise-Induced; Drug Therapy, Combination; Drug Tolerance; Exercise Test; Humans;

1983
Effect of a calcium antagonist, nifedipine, in exercise-induced asthma.
    Respiration; international review of thoracic diseases, 1984, Volume: 45, Issue:3

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Clinical Trials as Topic; Cromolyn Sodium; Doub

1984
A calcium antagonist, nifedipine, modifies exercise-induced asthma.
    Thorax, 1981, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl

1981
Inhibition of exercise-induced asthma by a calcium antagonist, nifedipine.
    The American review of respiratory disease, 1981, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Calcium; Female; Humans; Lung Volume Measuremen

1981
[Asthma of physical effort and the effect of nifedipine and diltiazem].
    Terapevticheskii arkhiv, 1991, Volume: 63, Issue:8

    Topics: Adult; Asthma, Exercise-Induced; Diltiazem; Female; Humans; Male; Nifedipine; Respiratory Function T

1991
[Pharmacological prevention of exercise-induced bronchospasm in patients with asthma].
    Pneumonologia polska, 1985, Volume: 53, Issue:4

    Topics: Adult; Aerosols; Albuterol; Aminophylline; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents;

1985
Comparison of nifedipine with a new calcium channel blocker, flordipine, in exercise-induced asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1987, Volume: 24, Issue:5

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Calcium Channel Blockers; Clinical Trials as Topic; Double-

1987
Comparison of PY 108-068, a new calcium antagonist, with nifedipine in exercise-induced asthma.
    Chest, 1986, Volume: 90, Issue:2

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchi; Calcium Channel Blockers; Clinical Tri

1986
Inhibition of exercise-induced asthma by nifedipine: a dose-response study.
    British journal of clinical pharmacology, 1987, Volume: 24, Issue:4

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Dose-Response Relationship, Drug; Female; Forced Expiratory

1987
The effect of nifedipine on exercise-induced asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1986, Volume: 23, Issue:1

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Double-Blind Method; Drug Evaluation; Female; H

1986
Calcium-channel blockers in prophylaxis and treatment of asthma.
    The American journal of cardiology, 1985, Jan-25, Volume: 55, Issue:3

    Topics: Animals; Antigens; Asthma; Asthma, Exercise-Induced; Bronchi; Bronchial Provocation Tests; Bronchodi

1985
Bronchodilatation and attenuation of exercise-induced bronchospasm by PY 108-068, a new calcium antagonist.
    The American review of respiratory disease, 1986, Volume: 133, Issue:1

    Topics: Adult; Asthma; Asthma, Exercise-Induced; Bronchodilator Agents; Calcium Channel Blockers; Female; Fo

1986

Other Studies

9 other studies available for nifedipine and Asthma, Exercise-Induced

ArticleYear
Calcium channel antagonists in coronary artery spasm and bronchial spasm. What do variant angina and bronchial asthma have in common?
    Chest, 1982, Volume: 82, Issue:4

    Topics: Animals; Asthma, Exercise-Induced; Bronchial Spasm; Calcium; Calcium Channel Blockers; Coronary Vaso

1982
[Effectiveness of the calcium antagonist nifedipine and the protease inhibitor with plasmin inactivating effect para-aminomethylbenzoic acid on stress-induced bronchial asthma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1984, Nov-01, Volume: 39, Issue:21

    Topics: 4-Aminobenzoic Acid; Adolescent; Adult; Airway Resistance; Aminobenzoates; Antifibrinolytic Agents;

1984
Calcium channel blocking agents in bronchial hyperreactivity.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Airway Resistance; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Bronchial Spasm; C

1984
Use of inhaled calcium channel blocking agents in the treatment of asthma.
    The Journal of asthma : official journal of the Association for the Care of Asthma, 1984, Volume: 21, Issue:6

    Topics: Aerosols; Airway Resistance; Allergens; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Test

1984
Effect of nifedipine on bronchomotor tone and histamine reactivity in asthma.
    British medical journal (Clinical research ed.), 1981, Sep-19, Volume: 283, Issue:6294

    Topics: Asthma; Asthma, Exercise-Induced; Blood Pressure; Humans; Nifedipine; Pyridines

1981
Calcium antagonists in experimental asthma.
    Clinical allergy, 1982, Volume: 12 Suppl

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Bronchial Provocation Tests; Calcium Channel Bl

1982
The effect of calcium antagonist, nifedipine in exercise-induced asthma.
    Clinical allergy, 1981, Volume: 11, Issue:5

    Topics: Adolescent; Adult; Asthma; Asthma, Exercise-Induced; Female; Forced Expiratory Volume; Humans; Male;

1981
[The effect of the calcium antagonist nifedipine on stress-induced bronchial asthma].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1989, Nov-15, Volume: 44, Issue:22

    Topics: Adolescent; Adult; Aged; Airway Resistance; Asthma; Asthma, Exercise-Induced; Exercise Test; Female;

1989
Exercise-induced asthma. Diagnostic clues with recommendation for treatment.
    Postgraduate medicine, 1985, Volume: 77, Issue:8

    Topics: Adrenergic beta-Agonists; Asthma; Asthma, Exercise-Induced; Bronchial Spasm; Cromolyn Sodium; Forced

1985