nifedipine has been researched along with Aortic Valve Insufficiency in 42 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
Aortic Valve Insufficiency: Pathological condition characterized by the backflow of blood from the ASCENDING AORTA back into the LEFT VENTRICLE, leading to regurgitation. It is caused by diseases of the AORTIC VALVE or its surrounding tissue (aortic root).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical experience with calcium antagonists in congestive heart failure has, to date, been mainly restricted to the use of nifedipine but there is either no or only a limited extent of information available on diltiazem and verapamil." | 3.66 | Calcium antagonists in heart failure. ( Camerini, F; Klugmann, S; Salvi, A, 1983) |
| "Nifedipine-treated animals displayed hemodynamics, LV dilatation, hypertrophy, and loss of function similar to those of the untreated group." | 1.35 | Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation. ( Arsenault, M; Beaudoin, J; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E, 2009) |
| "The effect on myocardial function and structure of long-term administration of quinapril (10-20 mg daily), an angiotensin-converting-enzyme (ACE) inhibitor, was investigated in 24 patients (18 men, 6 women; mean age 48 [20-65] years) with chronic isolated asymptomatic aortic or mitral regurgitation." | 1.29 | [Long-term treatment with quinapril in chronic aortic and mitral insufficiency]. ( Schömig, A; Schön, HR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (35.71) | 18.7374 |
| 1990's | 14 (33.33) | 18.2507 |
| 2000's | 13 (30.95) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plante, E | 2 |
| Lachance, D | 1 |
| Beaudoin, J | 1 |
| Champetier, S | 1 |
| Roussel, E | 1 |
| Arsenault, M | 2 |
| Couet, J | 2 |
| Gaudreau, M | 1 |
| Dumas, MP | 1 |
| Drolet, MC | 1 |
| Scheuble, A | 1 |
| Vahanian, A | 1 |
| Scognamiglio, R | 4 |
| Negut, C | 1 |
| Palisi, M | 1 |
| Fasoli, G | 4 |
| Dalla-Volta, S | 3 |
| Bashore, TM | 1 |
| Evangelista, A | 1 |
| Tornos, P | 1 |
| Sambola, A | 1 |
| Permanyer-Miralda, G | 1 |
| Soler-Soler, J | 1 |
| Carabello, BA | 1 |
| Takagi, H | 1 |
| Umemoto, T | 1 |
| Rahimtoola, SH | 3 |
| Krasuski, RA | 1 |
| Griffin, BP | 1 |
| Afshinnia, F | 1 |
| Shen, WF | 4 |
| Roubin, GS | 2 |
| Hirasawa, K | 2 |
| Uren, RF | 2 |
| Hutton, BF | 2 |
| Harris, PJ | 2 |
| Fletcher, PJ | 2 |
| Kelly, DT | 2 |
| Fioretti, P | 2 |
| Benussi, B | 2 |
| Klugmann, S | 3 |
| Camerini, F | 3 |
| Salvi, A | 1 |
| Sclavo, M | 2 |
| De Bernardi, A | 2 |
| Tunno, C | 2 |
| Bevilacqua, R | 2 |
| Angelino, PF | 2 |
| Scardi, S | 1 |
| Brower, RW | 1 |
| Reifart, N | 1 |
| Kober, G | 1 |
| Schulz, W | 1 |
| Kaltenbach, M | 1 |
| Rousseau, MF | 1 |
| Pouleur, H | 1 |
| Charlier, AA | 1 |
| Brasseur, LA | 1 |
| Jebavý, P | 1 |
| Fournier Andray, JA | 1 |
| Cubero García, J | 1 |
| Coats, AJ | 1 |
| Klein, LJ | 1 |
| Reichert, CL | 1 |
| Arnold, AE | 1 |
| Schön, HR | 2 |
| Schömig, A | 1 |
| Manyari, DE | 1 |
| Yunus, A | 1 |
| Mangieri, E | 1 |
| Tanzilli, G | 1 |
| Acri, A | 1 |
| Mangiaracina, F | 1 |
| Ferri, FM | 1 |
| Mastroianni, MA | 1 |
| Nardi, M | 1 |
| Pignatelli, A | 1 |
| Abbolito, S | 1 |
| Missiroli, B | 1 |
| Nistri, S | 1 |
| Dalla Volta, S | 1 |
| Bonow, RO | 1 |
| Röthlisberger, C | 1 |
| Sareli, P | 1 |
| Wisenbaugh, T | 1 |
| Gentile, F | 1 |
| Ornaghi, M | 1 |
| Esposti, D | 1 |
| Triulzi, MO | 1 |
| Banaszewski, M | 1 |
| Rydlewska-Sadowska, W | 1 |
| Rubkiewicz, S | 1 |
| Grayburn, PA | 1 |
| Novaro, GM | 1 |
| Rodriguez, LL | 1 |
| Montemurro, D | 1 |
| Ronzani, G | 1 |
| Gozzelino, G | 1 |
| Spadaccini, L | 1 |
| Panataro, C | 1 |
| Brusca, A | 1 |
| Ponchia, A | 1 |
| Crawford, MH | 1 |
| Wilson, RS | 1 |
| O'Rourke, RA | 1 |
| Vittitoe, JA | 1 |
| Gong, LS | 2 |
| Visintin, L | 1 |
4 reviews available for nifedipine and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Aortic insufficiency: defining the role of pharmacotherapy.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; H | 2005 |
Medical treatment of chronic valvular regurgitation.
Topics: Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease; Humans; Isoqu | 1995 |
Vasodilator therapy for chronic aortic and mitral regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Digoxin; Heart Ventricles; Hemodynamics; Humans; Mitral | 2000 |
Vasodilator therapy in chronic severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Digitalis Glycosides; Echocardiography; Hemodynamics; H | 1990 |
7 trials available for nifedipine and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Long-term vasodilator therapy in patients with severe aortic regurgitation.
Topics: Actuarial Analysis; Adult; Aortic Valve Insufficiency; Blood Pressure; Enalapril; Female; Follow-Up | 2005 |
[Left ventricular contractility, relaxation and regional wall motion following intracoronary injection of nifedipine. Evaluation by m-mode echocardiography].
Topics: Adult; Aortic Valve Insufficiency; Cardiomyopathies; Coronary Disease; Echocardiography; Female; Hea | 1982 |
Nifedipine in asymptomatic patients with severe aortic regurgitation and normal left ventricular function.
Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Digoxin; Female; Follow-Up Studies; Heart Valve | 1994 |
Comparison of single-dose nifedipine and captopril for chronic severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Captopril; Chronic Disease; Double-Blind Method; Hemodynamics; Humans; N | 1993 |
Captopril or nifedipine? Comparison of rest and exercise acute effects and long-term therapy in chronic isolated asymptomatic moderate to severe aortic regurgitation.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Blood Pressure; C | 1998 |
Long-term nifedipine unloading therapy in asymptomatic patients with chronic severe aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Double-Blind Method; Echocardiography; Female; F | 1990 |
Effect of digoxin and vasodilators on left ventricular function in aortic regurgitation.
Topics: Adult; Analysis of Variance; Aortic Valve Insufficiency; Digoxin; Echocardiography; Exercise Test; H | 1989 |
31 other studies available for nifedipine and Aortic Valve Insufficiency
| Article | Year |
|---|---|
Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic V | 2009 |
Left ventricular response to sustained volume overload from chronic aortic valve regurgitation in rats.
Topics: Animals; Aortic Valve Insufficiency; Calcium Channel Blockers; Echocardiography; Hypertrophy, Left V | 2003 |
Long-term survival and functional results after aortic valve replacement in asymptomatic patients with chronic severe aortic regurgitation and left ventricular dysfunction.
Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Combined Modality Therapy; Drug Administration S | 2005 |
Afterload reduction in chronic aortic regurgitation: it sure seems like a good idea.
Topics: Aortic Valve Insufficiency; Drug Administration Schedule; Heart Valve Prosthesis Implantation; Human | 2005 |
Vasodilators in aortic regurgitation--where is the evidence of their effectiveness?
Topics: Aortic Valve Insufficiency; Enalapril; Heart Valve Prosthesis Implantation; Humans; Nifedipine; Trea | 2005 |
Vasodilators in aortic regurgitation.
Topics: Aortic Valve Insufficiency; Blood Pressure; Enalapril; Heart Valve Prosthesis Implantation; Humans; | 2006 |
Vasodilators in aortic regurgitation.
Topics: Aortic Valve Insufficiency; Blood Pressure; Enalapril; Heart Valve Prosthesis Implantation; Heart Ve | 2006 |
Vasodilators in aortic regurgitation.
Topics: Antihypertensive Agents; Aortic Valve Insufficiency; Disease Progression; Enalapril; Humans; Hyperte | 2006 |
Vasodilators in aortic regurgitation.
Topics: Aortic Valve Insufficiency; Enalapril; Humans; Hypertrophy, Left Ventricular; Nifedipine; Vasodilato | 2006 |
Abnormal left ventricular response to isometric exercise in pure, isolated aortic regurgitation: beneficial effects of nifedipine.
Topics: Adult; Aortic Valve Insufficiency; Blood Pressure; Cardiac Output; Female; Heart Rate; Heart Ventric | 1984 |
Noninvasive assessment of acute effects of nifedipine on rest and exercise hemodynamics and cardiac function in patients with aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Cardiac Output; Exercise Test; Female; Heart; Heart Rate; Hemodyn | 1984 |
Acute hemodynamic effects of nifedipine at rest and during stress in severe aortic incompetence.
Topics: Adult; Aged; Aortic Valve Insufficiency; Cardiac Catheterization; Coronary Angiography; Exercise Tes | 1983 |
Calcium antagonists in heart failure.
Topics: Aortic Valve Insufficiency; Calcium Channel Blockers; Coronary Disease; Diltiazem; Heart Failure; He | 1983 |
[Therapeutic criteria for the use of nifedipine in patients with chronic aortic insufficiency].
Topics: Aortic Valve Insufficiency; Cardiac Output; Female; Heart Rate; Humans; Male; Nifedipine; Vascular R | 1982 |
[Therapeutic criteria in the use of nifedipine in patients with chronic aortic insufficiency].
Topics: Adult; Aortic Valve Insufficiency; Echocardiography; Female; Hemodynamics; Humans; Male; Nifedipine | 1982 |
Afterload reduction with nifedipine in aortic insufficiency.
Topics: Adult; Aged; Aortic Valve Insufficiency; Blood Pressure; Cardiac Volume; Female; Heart Ventricles; H | 1982 |
Assessment of left ventricular relaxation in patients with valvular regurgitation.
Topics: Adult; Aged; Aortic Valve Insufficiency; Cardiac Catheterization; Cineangiography; Female; Heart Ven | 1982 |
[Changes in hemodynamics after administration of nifedipine in aortic defects].
Topics: Aortic Valve Insufficiency; Aortic Valve Stenosis; Hemodynamics; Humans; Nifedipine; Pyridines | 1982 |
[Hemodynamic effect of nifedipine in left valvular diseases with volumetric overload].
Topics: Adolescent; Adult; Aortic Valve Insufficiency; Female; Hemodynamics; Humans; Male; Middle Aged; Mitr | 1982 |
Nifedipine in severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Research Design | 1995 |
Nifedipine in severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Placebos | 1995 |
[Long-term treatment with quinapril in chronic aortic and mitral insufficiency].
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Aortic Valve Insufficiency; Chronic Disease; | 1995 |
Nifedipine in severe aortic regurgitation.
Topics: Aortic Valve Insufficiency; Digoxin; Humans; Nifedipine; Ventricular Function, Left | 1995 |
[The effects of sublingual nifedipine on isometric stress in patients with severe aortic insufficiency. An acute hemodynamic study].
Topics: Acute Disease; Administration, Sublingual; Adult; Aortic Valve Insufficiency; Cardiac Catheterizatio | 1994 |
Management of chronic aortic regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Digoxin; Heart Valve Prosthesis; Humans; Nifedipine; St | 1994 |
Hemodynamic effects of nifedipine in patients with asymptomatic aortic regurgitation: evaluation by Doppler echocardiography.
Topics: Administration, Sublingual; Adolescent; Adult; Aged; Aortic Valve Insufficiency; Blood Flow Velocity | 1993 |
Left ventricular outflow tract obstruction unmasked by nifedipine: a therapeutic pitfall in the management of chronic aortic regurgitation.
Topics: Aortic Valve Insufficiency; Chronic Disease; Echocardiography; Humans; Male; Middle Aged; Nifedipine | 2001 |
[Spectral analysis and color-coded Doppler study of the changes in aortic regurgitation induced by vasodilators in asymptomatic patients with severe aortic insufficiency].
Topics: Aortic Valve Insufficiency; Blood Pressure; Chronic Disease; Echocardiography, Doppler; Female; Hear | 1990 |
Left ventricular diastolic filling characteristics and nifedipine effects on chronic aortic regurgitation.
Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Diastole; Female; Heart Function Tests; Heart Ve | 1988 |
[Characteristics of left ventricular diastolic filling and effects of nifedipine in patients with chronic aortic regurgitation].
Topics: Adult; Aortic Valve Insufficiency; Chronic Disease; Diastole; Female; Heart Ventricles; Humans; Male | 1987 |
Effects of unloading and positive inotropic interventions on left ventricular function in asymptomatic patients with chronic severe aortic insufficiency.
Topics: Adult; Aortic Valve Insufficiency; Digoxin; Drug Therapy, Combination; Echocardiography; Female; Hea | 1987 |