Page last updated: 2024-11-01

nifedipine and Anterior Choroidal Artery Infarction

nifedipine has been researched along with Anterior Choroidal Artery Infarction in 25 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"We examined the effect of a Ca antagonist (nilvadipine) on the occurrence or recurrence of symptomatic stroke in hypertensive patients with MRI-defined asymptomatic cerebral infarction (ACI), periventricular hyperintensity (PVH), and deep and subcortical white matter hyperintensity (DSWMH), with or without a history of stroke, and evaluated the effect of long-term treatment on the lesions."9.12Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment. ( Fukuuchi, Y; Hirai, S; Okudera, T; Shinohara, Y; Terashi, A; Tohgi, H; Yamaguchi, T, 2007)
"The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats."7.69Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996)
"Extracellular Ca2+ (Ca2+ e) changes in the cerebral infarction areas of the rats with the double-tubulus calcium ion-selective microelectrodes made of calcium active material, di-2-isooctylphenyl calcium phosphate to observe the effects of two concentrations of nifedipine given before the middle cerebral artery (MCA) occlusion."7.68[Extracellular calcium in the rat brains and the effects of nifedipine in experimental cerebral infarction using calcium ion selective microelectrodes in vivo]. ( Niu, G, 1992)
"The effect of nilvadipine, a newly developed calcium antagonist, on regional cerebral blood flow (rCBF) was investigated in 7 patients with chronic cerebral infarction."7.68Effect of single oral administration of nilvadipine on cerebral blood flow in chronic cerebral infarction. ( Bokura, K; Kobayashi, S; Murao, M; Okada, K; Suyama, N; Tsunematsu, T; Yamaguchi, S, 1992)
"We studied the efficacy of preischemic and postischemic systemic treatment with a new calcium antagonist nilvadipine in a permanent focal cerebral ischemia model of spontaneously hypertensive rats."7.68Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Handa, J; Matsuda, M; Shiino, A; Susumu, T, 1991)
"The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion."7.68Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991)
"Nifedipine was administered intracerebroventricularly (5 microL) or intrathecally (20 microL) at graded doses (0."5.30Effects of nifedipine on bladder overactivity in rats with cerebral infarction. ( Komatsu, K; Kontani, H; Mita, E; Nakamura, Y; Namiki, M; Yokoyama, O, 1999)
"We examined the effect of a Ca antagonist (nilvadipine) on the occurrence or recurrence of symptomatic stroke in hypertensive patients with MRI-defined asymptomatic cerebral infarction (ACI), periventricular hyperintensity (PVH), and deep and subcortical white matter hyperintensity (DSWMH), with or without a history of stroke, and evaluated the effect of long-term treatment on the lesions."5.12Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment. ( Fukuuchi, Y; Hirai, S; Okudera, T; Shinohara, Y; Terashi, A; Tohgi, H; Yamaguchi, T, 2007)
"The protective effect of nilvadipine, a Ca2+ antagonist, on cerebral ischemia was investigated in spontaneously hypertensive rats."3.69Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Fukasawa, H; Kawamura, S; Li, Y; Shirasawa, M; Yasui, N, 1996)
" DESIGN OF STUDIES: Mean cerebral circulation parameters were studied in chronic stroke patients with hypertension and treated acutely or chronically (2 weeks) with nicardipine or nifedipine retard."3.68Effects of dihydropyridines on cerebral blood vessels. ( Hashimoto, H; Kuriyama, Y; Nagatsuka, K; Omae, T; Sawada, T, 1993)
"Extracellular Ca2+ (Ca2+ e) changes in the cerebral infarction areas of the rats with the double-tubulus calcium ion-selective microelectrodes made of calcium active material, di-2-isooctylphenyl calcium phosphate to observe the effects of two concentrations of nifedipine given before the middle cerebral artery (MCA) occlusion."3.68[Extracellular calcium in the rat brains and the effects of nifedipine in experimental cerebral infarction using calcium ion selective microelectrodes in vivo]. ( Niu, G, 1992)
"The effect of nilvadipine, a newly developed calcium antagonist, on regional cerebral blood flow (rCBF) was investigated in 7 patients with chronic cerebral infarction."3.68Effect of single oral administration of nilvadipine on cerebral blood flow in chronic cerebral infarction. ( Bokura, K; Kobayashi, S; Murao, M; Okada, K; Suyama, N; Tsunematsu, T; Yamaguchi, S, 1992)
"The effects of nilvadipine, a dihydropyridine type calcium channel blocker, on cerebral infarction induced by focal brain ischemia was studied in rats."3.68Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats. ( Handa, J; Mori, J; Satoh, H; Shiino, A; Susumu, T; Takakura, S, 1991)
"We investigated the effects of nilvadipine, a calcium antagonist, on cerebral ischemia in rats."3.68Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991)
"We studied the efficacy of preischemic and postischemic systemic treatment with a new calcium antagonist nilvadipine in a permanent focal cerebral ischemia model of spontaneously hypertensive rats."3.68Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats. ( Handa, J; Matsuda, M; Shiino, A; Susumu, T, 1991)
"The effects of nilvadipine, a Ca2+ entry blocker, on focal cerebral ischemia were investigated in rats having unilateral middle cerebral artery occlusion."3.68Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats. ( Fukasawa, H; Kawamura, S; Shirasawa, M; Yasui, N, 1991)
"Nifedipine (Adalat) was used in managing acute hypertension in 20 patients with coronary heart disease during endarterectomy for carotid stenosis."3.67[Treatment of hypertensive crises with nifedipine (Adalat) in patients at risk of infarct during interventions on the extracranial cerebral vessels]. ( Balzer, K; Fanoulas, G; Fidorra, K; Gresser, S; Müller, C, 1987)
"A 31-year-old woman developed bilateral posterior ischemic optic neuropathy and infarctions of the cerebral arterial border zones and spinal cord after correction of malignant hypertension."1.35Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension. ( An, SJ; Choi, JH; Choi, KD; Kim, HJ; Kim, JS; Lee, JE, 2008)
"Nifedipine was administered intracerebroventricularly (5 microL) or intrathecally (20 microL) at graded doses (0."1.30Effects of nifedipine on bladder overactivity in rats with cerebral infarction. ( Komatsu, K; Kontani, H; Mita, E; Nakamura, Y; Namiki, M; Yokoyama, O, 1999)
"In addition, evolution of cerebral infarction was studied at 6 hours and 12 hours post-occlusion by magnetic resonance imaging (MRI)."1.28[Ca++ antagonist and acute brain ischemia: effects of nilvadipine and nicardipine on middle cerebral artery occlusion in rats]. ( Handa, J; Inubushi, T; Kido, C; Matsuda, M; Morikawa, S; Shiino, A; Susumu, T, 1991)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.00)18.7374
1990's19 (76.00)18.2507
2000's4 (16.00)29.6817
2010's1 (4.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Choi, JH1
Choi, KD1
Kim, JS1
Kim, HJ1
Lee, JE1
An, SJ1
Wu, CS1
Sung, SF1
Tong, SH1
Ong, CT1
Takahara, A1
Konda, T1
Enomoto, A1
Kondo, N1
Shinohara, Y2
Tohgi, H1
Hirai, S1
Terashi, A1
Fukuuchi, Y1
Yamaguchi, T1
Okudera, T1
Li, Y3
Kawamura, S5
Yasui, N5
Shirasawa, M5
Fukasawa, H5
Kuriyama, Y1
Hashimoto, H1
Nagatsuka, K1
Sawada, T1
Omae, T1
Lee, YJ1
Jy, W1
Horstman, LL1
Janania, J1
Reyes, Y1
Kelley, RE1
Ahn, YS1
Takagi, Y1
Hashimoto, N1
Goto, Y1
Azuma, T1
Matsubara, T1
Nagai, Y1
Funauchi, M1
Fujimoto, T1
Saito, T1
Tone, K1
Sakoda, S1
Miyazaki, H1
Tanaka, S1
Fujii, Y1
Shimizu, K1
Nagashima, K1
Kamibayashi, M1
Uehara, T1
Okuma, Y1
Nomura, Y1
Nakamura, Y1
Yokoyama, O1
Komatsu, K1
Mita, E1
Namiki, M1
Kontani, H1
Niu, G1
Morton, C1
Hickey-Dwyer, M1
Kobayashi, S1
Yamaguchi, S1
Okada, K1
Suyama, N1
Bokura, K1
Murao, M1
Tsunematsu, T1
Hayashi, T1
Goto, T1
Tateishi, T1
Yoshimine, N1
Kuzuya, F1
Akopov, SE1
Grigorian, GS1
Kazarian, AV1
Mkhitarian, GS1
Tunian, IuS1
Gabrielian, ES1
Takakura, S1
Susumu, T3
Satoh, H1
Mori, J1
Shiino, A3
Handa, J3
Matsuda, M2
Morikawa, S1
Kido, C1
Inubushi, T1
Müller, C1
Gresser, S1
Fanoulas, G1
Fidorra, K1
Balzer, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Phase III-b, Multi-centre, Open-label, Parallel Study of Enoxaparin (Low Molecular Weight Heparin) Given Concomitantly With Chemotherapy vs Chemotherapy Alone in Patients With Inoperable Gastric and Gastro-oesophageal Cancer[NCT00718354]Phase 3740 participants (Actual)Interventional2008-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for nifedipine and Anterior Choroidal Artery Infarction

ArticleYear
[PICA study--hypertension and asymptomatic cerebral infarction].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Oct-28, Volume: 64 Suppl 7

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarcti

2006

Trials

2 trials available for nifedipine and Anterior Choroidal Artery Infarction

ArticleYear
Effect of the Ca antagonist nilvadipine on stroke occurrence or recurrence and extension of asymptomatic cerebral infarction in hypertensive patients with or without history of stroke (PICA Study). 1. Design and results at enrollment.
    Cerebrovascular diseases (Basel, Switzerland), 2007, Volume: 24, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Cerebral Infarcti

2007
Effects of antihypertensive agents on circadian blood pressure in hypertensive patients with previous brain infarction.
    Journal of human hypertension, 1997, Volume: 11, Issue:10

    Topics: Acebutolol; Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Ca

1997

Other Studies

22 other studies available for nifedipine and Anterior Choroidal Artery Infarction

ArticleYear
Simultaneous posterior ischemic optic neuropathy, cerebral border zone infarction, and spinal cord infarction after correction of malignant hypertension.
    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society, 2008, Volume: 28, Issue:3

    Topics: Adult; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Brain; Brain Stem Infarctions; C

2008
Multiple cerebral infarctions related to famotidine-induced eosinophilia.
    Journal of neurology, 2012, Volume: 259, Issue:10

    Topics: Acarbose; Adrenergic alpha-1 Receptor Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulc

2012
Neuroprotective effects of a dual L/N-type Ca(2+) channel blocker cilnidipine in the rat focal brain ischemia model.
    Biological & pharmaceutical bulletin, 2004, Volume: 27, Issue:9

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Typ

2004
Therapeutic effects of nilvadipine on rat focal cerebral ischemia.
    Experimental brain research, 1994, Volume: 99, Issue:1

    Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infarction; Is

1994
Effects of dihydropyridines on cerebral blood vessels.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:6

    Topics: Administration, Oral; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Cerebrovascu

1993
Elevated platelet microparticles in transient ischemic attacks, lacunar infarcts, and multiinfarct dementias.
    Thrombosis research, 1993, Nov-15, Volume: 72, Issue:4

    Topics: Adult; Aged; Alzheimer Disease; Blood Platelets; Cerebral Infarction; Dementia, Multi-Infarct; Femal

1993
Protective effect of nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats.
    Neurologia medico-chirurgica, 1996, Volume: 36, Issue:3

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Dose-Response Relationship,

1996
Haemodynamic ischaemia in paediatric moyamoya disease associated with renovascular hypertension.
    Acta neurochirurgica, 1997, Volume: 139, Issue:3

    Topics: Antihypertensive Agents; Brain; Cerebral Angiography; Cerebral Cortex; Cerebral Infarction; Cerebral

1997
Effects of treatment with nilvadipine on cerebral ischemia in rats.
    The Tohoku journal of experimental medicine, 1998, Volume: 185, Issue:4

    Topics: Animals; Antihypertensive Agents; Brain; Calcium Channel Blockers; Cerebral Infarction; Hypertension

1998
Neuroprotective effects of a dihydropyridine derivative, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarbox ylic acid methyl 6-(5-phenyl-3-pyrazolyloxy)hexyl ester (CV-159), on rat ischemic brain injury.
    Life sciences, 1999, Volume: 64, Issue:10

    Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Prote

1999
Effects of nifedipine on bladder overactivity in rats with cerebral infarction.
    The Journal of urology, 1999, Volume: 162, Issue:4

    Topics: Animals; Calcium Channel Blockers; Cerebral Infarction; Male; Nifedipine; Rats; Rats, Sprague-Dawley

1999
[Extracellular calcium in the rat brains and the effects of nifedipine in experimental cerebral infarction using calcium ion selective microelectrodes in vivo].
    Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 1992, Volume: 25, Issue:1

    Topics: Animals; Brain; Calcium; Calcium Channels; Cerebral Infarction; Extracellular Space; Male; Microelec

1992
Cortical blindness after nifedipine treatment.
    BMJ (Clinical research ed.), 1992, Sep-19, Volume: 305, Issue:6855

    Topics: Blindness; Cerebral Infarction; Humans; Male; Middle Aged; Nifedipine; Occipital Lobe

1992
Effect of single oral administration of nilvadipine on cerebral blood flow in chronic cerebral infarction.
    Angiology, 1992, Volume: 43, Issue:10

    Topics: Administration, Oral; Aged; Aged, 80 and over; Blood Pressure; Calcium Channel Blockers; Cerebral In

1992
Nocturnal blood pressure monitored by ambulatory blood pressure measurement in elderly hypertensive patients.
    Internal medicine (Tokyo, Japan), 1992, Volume: 31, Issue:4

    Topics: Aged; Blood Pressure; Blood Pressure Determination; Cerebral Infarction; Circadian Rhythm; Diabetes

1992
[Status of the prostacyclin-thromboxane balance in patients with cerebrovascular disorders and the effect of the treatment with nifedipine].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1991, Volume: 91, Issue:7

    Topics: 6-Ketoprostaglandin F1 alpha; Acute Disease; Aged; Cerebral Infarction; Cerebrovascular Circulation;

1991
Nilvadipine, a new calcium channel blocker, reduces ischemic brain injury in rats.
    Japanese journal of pharmacology, 1991, Volume: 56, Issue:4

    Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Cerebral Infarction; Nicardipine; Nifedipine; Rat

1991
[Ca++ antagonist and acute brain ischemia: effects of nilvadipine and nicardipine on middle cerebral artery occlusion in rats].
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1991, Jan-01, Volume: 60, Issue:1

    Topics: Acute Disease; Animals; Calcium Channel Blockers; Cerebral Infarction; Constriction; Ischemic Attack

1991
Attenuated neuropathology by nilvadipine after middle cerebral artery occlusion in rats.
    Stroke, 1991, Volume: 22, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Brain; Brain Ischemia; Calcium Channel Blockers; Cerebral Arte

1991
Effects of the calcium antagonist nilvadipine on focal cerebral ischemia in spontaneously hypertensive rats.
    Surgical neurology, 1991, Volume: 35, Issue:2

    Topics: Animals; Blood Pressure; Brain Ischemia; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infar

1991
Effects of a Ca2+ entry blocker (nilvadipine) on acute focal cerebral ischemia in rats.
    Experimental brain research, 1991, Volume: 83, Issue:2

    Topics: Acute Disease; Animals; Brain; Brain Edema; Brain Ischemia; Calcium Channel Blockers; Cerebral Infar

1991
[Treatment of hypertensive crises with nifedipine (Adalat) in patients at risk of infarct during interventions on the extracranial cerebral vessels].
    Anasthesie, Intensivtherapie, Notfallmedizin, 1987, Volume: 22, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Cardiac Output, Low; Carotid Artery Diseases; Carotid Artery, Intern

1987