nifedipine has been researched along with Anoxemia in 115 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We have studied the prophylactic administration of nifedipine and its molecular mechanism involved in reducing the transvascular leakage and inflammation in rats under hypoxia." | 7.78 | Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB. ( M, C; Mathew, T; P, H; S K S, S; S, S, 2012) |
| "The combination with olmesartan and nifedipine, as well as a monotherapy with olmesartan, exerts preferable cardioprotection in diabetic mice exposed to recurrent hypoxia." | 7.76 | Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice. ( Hayashi, T; Kitada, K; Kitaura, Y; Matsumoto, C; Matsumura, Y; Miyamura, M; Mori, T; Okada, Y; Sohmiya, K; Ukimura, A; Yamashita, C; Yoshioka, T, 2010) |
| "The effects of hypoxia on the vasodilator response of endothelium-denuded rat aortic rings to the calcium channel blocker, nifedipine, were examined." | 7.73 | Effects of hypoxia on the vasodilator activity of nifedipine and evidence of secondary pharmacological properties. ( Broadley, KJ; Penson, PE, 2006) |
| "A new model of acute lung injury was established by administering oleic acid into superior vena cava in experimental rat during acute hypoxia, which was formed by putting the animal in a hypobaric room, and reduced the pressure gradually in uniform speed till a simulated environment of 6000 m above sea level was formed and lasted for 12 hours." | 7.70 | [Experimental study on effect of altitude xishi capsule in treating oleic acid induced lung injury in acute hypoxia rats]. ( Cui, S; Guo, X, 1998) |
| " We wanted to determine whether nifedipine treatment prevents the increased pulmonary vascular resistance, blunted pulmonary vascular responses to acetylcholine, and reduced lung endothelial nitric oxide synthase (eNOS) amounts that we have found in a newborn model of chronic hypoxia-induced pulmonary hypertension." | 7.70 | Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. ( Fike, CD; Kaplowitz, MR, 1999) |
| "This study was performed to assess whether nifedipine could prevent the decrease in hepatic cytochrome P450 induced by acute moderate hypoxia or an inflammatory reaction." | 7.69 | Effect of nifedipine on the elimination of theophylline in the rabbit subjected to hypoxia or to an inflammatory reaction. ( Barakat, M; du Souich, P, 1996) |
| "Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes." | 7.69 | [Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994) |
| "The aim of the present study was to determine whether calcium channel antagonists attenuated hypoxia/hypoglycemia- or glutamate-induced reduction in 2-deoxyglucose (2-DG) uptake of hippocampal slices obtained from ethanol withdrawal rats." | 7.69 | Calcium channel blockers improve hypoxia/hypoglycemia-induced impairment of rat hippocampal 2-deoxyglucose uptake in vitro after ethanol withdrawal. ( Shibata, S; Shindou, T; Tominaga, K; Watanabe, S, 1995) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 7.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| " If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability and the therapeutic effect of nifedipine by altering the metabolic activity of the gut microbiota." | 5.48 | Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine. ( Chen, Y; Jia, Z; Sun, Y; Wang, R; Zhang, J, 2018) |
| "Nifedipine was then administered sublingually in a dose of 1 mg/kg and produced an immediate and dramatic improvement in the right radial artery pO2 that was sustained despite persistence of the right-to-left shunt." | 5.28 | [Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case]. ( Burguet, A; Destuynder, R; Fromentin, C; Menget, A, 1989) |
| "Nifedipine has recently been reported to reduce pulmonary artery pressure and pulmonary vascular resistance during rest and exercise in adult patients with hypoxic pulmonary hypertension from chronic obstructive pulmonary disease." | 5.27 | Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale. ( Fitzpatrick, S; Kennedy, TP; Michael, JR; Rosenstein, BJ, 1984) |
| " Biochemical evidence suggests that pulmonary vasoconstriction results from the transmembrane flux of calcium into vascular smooth muscle; accordingly, the pulmonary pressor responses in experimental hypoxic pulmonary hypertension can be attenuated by verapamil and nifedipine." | 4.77 | Therapeutic application of calcium-channel antagonists for pulmonary hypertension. ( Packer, M, 1985) |
| "Male ICR mice were divided into 5 groups: control group, hypoxia group, hypoxia group treated with nifedipine (10 mg/kg), hypoxia groups treated with CPU86017-RS (60 or 80 mg/kg)." | 3.78 | CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines. ( Cheng, YS; Dai, DZ; Dai, Y; Yu, F; Zhang, C; Zhang, GL, 2012) |
| "We have studied the prophylactic administration of nifedipine and its molecular mechanism involved in reducing the transvascular leakage and inflammation in rats under hypoxia." | 3.78 | Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB. ( M, C; Mathew, T; P, H; S K S, S; S, S, 2012) |
| " Physiological levels of hypoxia (Po(2) ∼30 mmHg) increased H(2)S levels in glomus cells, and dl-propargylglycine (PAG), a CSE inhibitor, prevented this response in a dose-dependent manner." | 3.78 | Endogenous H2S is required for hypoxic sensing by carotid body glomus cells. ( Fox, AP; Gadalla, MM; Kumar, GK; Makarenko, VV; Nanduri, J; Prabhakar, NR; Raghuraman, G; Snyder, SH, 2012) |
| "The combination with olmesartan and nifedipine, as well as a monotherapy with olmesartan, exerts preferable cardioprotection in diabetic mice exposed to recurrent hypoxia." | 3.76 | Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice. ( Hayashi, T; Kitada, K; Kitaura, Y; Matsumoto, C; Matsumura, Y; Miyamura, M; Mori, T; Okada, Y; Sohmiya, K; Ukimura, A; Yamashita, C; Yoshioka, T, 2010) |
| "The effects of hypoxia on the vasodilator response of endothelium-denuded rat aortic rings to the calcium channel blocker, nifedipine, were examined." | 3.73 | Effects of hypoxia on the vasodilator activity of nifedipine and evidence of secondary pharmacological properties. ( Broadley, KJ; Penson, PE, 2006) |
| " Male Sprague-dawley Rats (220 +/- 20 G) Were Divided Into Four Groups: (I) Control; (Ii) Untreated Hypoxic (28 Days Hypoxia); (Iii) Hypoxic Rats Treated In The Last 5 Days Of Hypoxia With Nifedipine(5 Mg/kg Per Day, P." | 3.73 | CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro. ( Dai, DZ; Dai, Y; Guan, L; Ji, M; Yuan, SH, 2006) |
| " Bovine brain microvessel endothelial cells were treated with A-23187 to increase intracellular calcium without hypoxia or treated with a calcium chelator (BAPTA) or calcium channel blockers (nifedipine or SKF-96365) and 6 h of hypoxia." | 3.72 | Protection against hypoxia-induced blood-brain barrier disruption: changes in intracellular calcium. ( Brown, RC; Davis, TP; Egleton, RD; Mark, KS, 2004) |
| "A new model of acute lung injury was established by administering oleic acid into superior vena cava in experimental rat during acute hypoxia, which was formed by putting the animal in a hypobaric room, and reduced the pressure gradually in uniform speed till a simulated environment of 6000 m above sea level was formed and lasted for 12 hours." | 3.70 | [Experimental study on effect of altitude xishi capsule in treating oleic acid induced lung injury in acute hypoxia rats]. ( Cui, S; Guo, X, 1998) |
| "In the lung, chronic hypoxia (CH) causes pulmonary arterial smooth muscle cell (PASMC) depolarization, elevated endothelin-1 (ET-1), and vasoconstriction." | 3.70 | L-type Ca(2+) channels, resting [Ca(2+)](i), and ET-1-induced responses in chronically hypoxic pulmonary myocytes. ( Sham, JS; Shimoda, LA; Shimoda, TH; Sylvester, JT, 2000) |
| " Rats were exposed to 3 wk of normoxia, hypoxia (10% O2), or monocrotaline (MCT; single dose = 60 mg/kg) and treated with either nothing (control), inhaled NO (20 ppm), or nifedipine (10 mg x kg(-1) x day(-1)." | 3.70 | Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats. ( Frank, DU; Horstman, DJ; McCall, DA; Rich, GF, 1999) |
| " We wanted to determine whether nifedipine treatment prevents the increased pulmonary vascular resistance, blunted pulmonary vascular responses to acetylcholine, and reduced lung endothelial nitric oxide synthase (eNOS) amounts that we have found in a newborn model of chronic hypoxia-induced pulmonary hypertension." | 3.70 | Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs. ( Fike, CD; Kaplowitz, MR, 1999) |
| "The aim of the present study was to determine whether calcium channel antagonists attenuated hypoxia/hypoglycemia- or glutamate-induced reduction in 2-deoxyglucose (2-DG) uptake of hippocampal slices obtained from ethanol withdrawal rats." | 3.69 | Calcium channel blockers improve hypoxia/hypoglycemia-induced impairment of rat hippocampal 2-deoxyglucose uptake in vitro after ethanol withdrawal. ( Shibata, S; Shindou, T; Tominaga, K; Watanabe, S, 1995) |
| "Experiments were carried on rats to study the preventive effects of calcium channel blockers Nitrendipine, Nifedipine and L-Arginine (L- Arginine is the physiological precursor of nitric oxide in endothelium-dependent relaxation) on chronic intermittent hypoxia induced pulmonary hypertension, on the right ventricular hypertrophy and pulmonary vascular pathologic changes." | 3.69 | [Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats]. ( Chen, SC; Li, MR; Ma, G, 1994) |
| "This study was performed to assess whether nifedipine could prevent the decrease in hepatic cytochrome P450 induced by acute moderate hypoxia or an inflammatory reaction." | 3.69 | Effect of nifedipine on the elimination of theophylline in the rabbit subjected to hypoxia or to an inflammatory reaction. ( Barakat, M; du Souich, P, 1996) |
| "Our purpose was to determine whether the fetal acidosis and hypoxia previously demonstrated in animal models with maternal nifedipine infusion is the result of a decrease in uteroplacental or fetoplacental blood flow and whether this effect is exacerbated by a higher drug concentration and duration of infusion." | 3.69 | Effect of nifedipine on fetal and maternal hemodynamics and blood gases in the pregnant ewe. ( Barnard, JM; Blea, CW; Hendricks, SK; Magness, RR; Phernetton, TM, 1997) |
| " infusion of U46619, a thromboxane A2 (TXA2) mimic, or by alveolar hypoxia." | 3.69 | HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs. ( Crowley, MR; Fineman, JR; Soifer, SJ, 1994) |
| "In anesthetized and thoracotomized 20 adult dogs under artificial respiration, the effects of calcium blockers (nifedipine, diltiazem and verapamil) on the mechanics of the left and right cardiac pumps under acute hypoxia were observed." | 3.68 | [Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia]. ( Gu, LM; Xiao, Y; Yuan, F; Zhou, ZN, 1992) |
| "Cardiovascular responses to the calcium antagonists verapamil and nifedipine were evaluated in a piglet model of hypoxic pulmonary hypertension." | 3.67 | The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet. ( Bancalari, E; Dickstein, PJ; Goldberg, RN; Trindade, O, 1984) |
| "We designed experiments to determine whether intermittent hypoxia would produce significant pathologic and physiologic changes in rats and whether pretreatment with a calcium channel blocker, nitrendipine, would reduce the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia." | 3.67 | Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats. ( Buescher, P; de la Monte, SM; Farrukh, I; Gottlieb, J; Gurtner, G; Hutchins, GM; Kennedy, TP; Lodato, R; Michael, JR; Rock, PC, 1986) |
| "Effects of hypoxia on atrioventricular conduction were investigated in the Langendorff-perfused isolated heart of the rabbit with various extracellular calcium concentrations ([Ca2+]) as well as in the presence of verapamil, nifedipine, N-(6-aminohexyl)-5-chloro-1-naphthalenesulphonamide (W-7) and chlorpromazine." | 3.67 | Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia. ( Anno, T; Kodama, I; Shibata, S; Toyama, J; Yamada, K, 1986) |
| " To determine whether protection is mediated in part by mechanisms unrelated to myocardial work and perfusion, we examined effects of diltiazem and nitrendipine on unperfused myocardium subjected to hypoxia." | 3.66 | Diltiazem and nitrendipine suppress hypoxic contracture in quiescent ventricular myocardium. ( Henry, PD; Wahl, AM, 1983) |
| "The influence of an increased Ca concentration on reactive hyperemia, work induced vasodilation and pharmacologically induced dilation (adenosine, nifedipine, verapamil) was studied in the blood perfused gastrocnemius of dogs." | 3.65 | [The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle]. ( Marten, W; Meyer, VU; Raff, WK; Schiffer, W, 1975) |
| "Individuals susceptible to high altitude pulmonary edema also show increased hypoxia vasoconstriction of pulmonary arterioles." | 2.38 | [Who gets altitude sickness?]. ( Bärtsch, P, 1992) |
| "As hypoxia is a major driver for the pathophysiology of COVID-19, it is crucial to characterize the hypoxic response at the cellular and molecular levels." | 1.62 | FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation. ( Gare, S; Giri, L; Gupta, P; Gupta, RK; Manohar, K; Misra, A; Saha, D; Sarkar, R, 2021) |
| "In fetal hypoxemia, sildenafil had detrimental effects on placental hemodynamics that disturbed placental gas exchange." | 1.56 | Effects of nifedipine and sildenafil on placental hemodynamics and gas exchange during fetal hypoxemia in a chronic sheep model. ( Acharya, G; Alanne, L; Bhide, A; Haapsamo, M; Hoffren, J; Huhta, H; Kokki, M; Lantto, J; Räsänen, J, 2020) |
| " If gut microbes are involved in the metabolism of nifedipine, plateau hypoxia may regulate the bioavailability and the therapeutic effect of nifedipine by altering the metabolic activity of the gut microbiota." | 1.48 | Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine. ( Chen, Y; Jia, Z; Sun, Y; Wang, R; Zhang, J, 2018) |
| "In the anoxia-tolerant crucian carp (Carassius carassius) cardiac activity varies according to the seasons." | 1.36 | Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists. ( Hälinen, M; Haverinen, J; Vornanen, M, 2010) |
| "The treatment with nifedipine in the CIH group attenuated blood pressure (159+/-2 mm Hg; P<0." | 1.35 | Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels. ( Gozal, D; Gu, Y; Nozdrachev, AD; Ortines, RV; Prabhu, SD; Soukhova-O'Hare, GK, 2008) |
| "IPA treated with thapsigargin (1 microM) in Ca2+-free solution to deplete Ca2+ stores showed sustained constriction upon re-exposure to Ca2+ and an increase in the rate of Mn2+ influx, suggesting capacitative Ca2+ entry." | 1.31 | Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat. ( Aaronson, PI; Hague, D; Robertson, TP; Ward, JP, 2000) |
| "Induction of chemical anoxia, using sodium azide in cerebellar granule cells maintained in primary culture, was evaluated as an in vitro assay for screening of potential neuroprotective compounds." | 1.29 | Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801. ( Drejer, J; Frandsen, A; Schousboe, A; Varming, T, 1996) |
| "Verapamil's inhibition was rapid in onset and disappearance; changes in glucose transport rate were detectable when verapamil was added to or removed from the incubation medium 15 min prior to measurement of glucose transport." | 1.28 | Diverse effects of calcium channel blockers on skeletal muscle glucose transport. ( Briggs-Tung, C; Cartee, GD; Holloszy, JO, 1992) |
| "By increased anaerobic glycolysis anoxia reduced contractile activity which after 30 min reached a plateau of approximately 50% of the initial aerobic value during approximately 2 hours." | 1.28 | Work and contraction curves of atrial muscle preparations during anoxia and reoxygenation influenced by cardio-tonic and cardio-depressive drugs. ( Englert, R; Siess, M; Stieler, K; Teutsch, I, 1991) |
| "Nifedipine was then administered sublingually in a dose of 1 mg/kg and produced an immediate and dramatic improvement in the right radial artery pO2 that was sustained despite persistence of the right-to-left shunt." | 1.28 | [Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case]. ( Burguet, A; Destuynder, R; Fromentin, C; Menget, A, 1989) |
| "Nifedipine has recently been reported to reduce pulmonary artery pressure and pulmonary vascular resistance during rest and exercise in adult patients with hypoxic pulmonary hypertension from chronic obstructive pulmonary disease." | 1.27 | Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale. ( Fitzpatrick, S; Kennedy, TP; Michael, JR; Rosenstein, BJ, 1984) |
| "Verapamil was more active than nifedipine in both models." | 1.27 | Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists. ( Jacobs, LW; Rosenberger, LB; Stanton, HC, 1984) |
| "Anoxia has been shown to potentiate the constrictor effects of 5-hydroxytryptamine (5HT) in isolated vascular tissue." | 1.27 | Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia. ( Balkon, J; Barrett, JA; DePaul Lynch, V; Smith, RD; Wolf, PS, 1986) |
| "After 45 min of anoxia and a 4- to 6-hr incubation in normal Ca++-containing media, cells from all segments were dead." | 1.27 | Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia. ( Schrier, RW; Schwertschlag, U; Wilson, P, 1986) |
| "Nifedipine is a potent slow channel calcium antagonist and systemic vasodilator recently reported to attenuate hypoxic pulmonary vasoconstriction in man." | 1.26 | Inhibition of hypoxic pulmonary vasoconstriction by nifedipine. ( Kennedy, T; Summer, W, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 47 (40.87) | 18.7374 |
| 1990's | 33 (28.70) | 18.2507 |
| 2000's | 20 (17.39) | 29.6817 |
| 2010's | 12 (10.43) | 24.3611 |
| 2020's | 3 (2.61) | 2.80 |
| Authors | Studies |
|---|---|
| Manohar, K | 1 |
| Gupta, RK | 1 |
| Gupta, P | 1 |
| Saha, D | 1 |
| Gare, S | 1 |
| Sarkar, R | 1 |
| Misra, A | 1 |
| Giri, L | 1 |
| Kim, D | 1 |
| Hogan, JO | 1 |
| White, C | 1 |
| Alanne, L | 1 |
| Bhide, A | 1 |
| Hoffren, J | 1 |
| Lantto, J | 1 |
| Huhta, H | 1 |
| Kokki, M | 1 |
| Haapsamo, M | 1 |
| Acharya, G | 1 |
| Räsänen, J | 1 |
| Zhang, J | 2 |
| Chen, Y | 1 |
| Sun, Y | 1 |
| Wang, R | 1 |
| Jia, Z | 1 |
| Wang, LA | 1 |
| Nguyen, DH | 1 |
| Mifflin, SW | 1 |
| Kojima, A | 1 |
| Matsumoto, A | 1 |
| Nishida, H | 1 |
| Reien, Y | 1 |
| Iwata, K | 1 |
| Shirayama, T | 1 |
| Yabe-Nishimura, C | 1 |
| Nakaya, H | 1 |
| Maimaitiyimin, D | 1 |
| Tao, Y | 1 |
| Shi, W | 1 |
| Upur, H | 1 |
| Aikemu, A | 1 |
| Hefter, D | 1 |
| Kaiser, M | 1 |
| Weyer, SW | 1 |
| Papageorgiou, IE | 1 |
| Both, M | 1 |
| Kann, O | 1 |
| Müller, UC | 1 |
| Draguhn, A | 1 |
| Peng, GY | 1 |
| Xu, J | 1 |
| Liu, RM | 1 |
| Hong, W | 1 |
| He, XM | 1 |
| Lin, YE | 1 |
| Tavakoli-Far, B | 1 |
| Rahbar-Roshandel, N | 1 |
| Rahimi-Moghaddam, P | 1 |
| Mahmoudian, M | 1 |
| Yamashita, C | 1 |
| Hayashi, T | 1 |
| Mori, T | 1 |
| Matsumoto, C | 1 |
| Kitada, K | 1 |
| Miyamura, M | 1 |
| Sohmiya, K | 1 |
| Ukimura, A | 1 |
| Okada, Y | 1 |
| Yoshioka, T | 1 |
| Kitaura, Y | 1 |
| Matsumura, Y | 1 |
| Vornanen, M | 1 |
| Hälinen, M | 1 |
| Haverinen, J | 1 |
| Liu, GL | 1 |
| Yu, F | 2 |
| Dai, DZ | 3 |
| Zhang, GL | 2 |
| Zhang, C | 2 |
| Dai, Y | 3 |
| Cheng, YS | 1 |
| S K S, S | 1 |
| P, H | 1 |
| Mathew, T | 1 |
| S, S | 1 |
| M, C | 1 |
| Makarenko, VV | 1 |
| Nanduri, J | 1 |
| Raghuraman, G | 1 |
| Fox, AP | 1 |
| Gadalla, MM | 1 |
| Kumar, GK | 1 |
| Snyder, SH | 1 |
| Prabhakar, NR | 1 |
| Lukyanetz, EA | 2 |
| Stanika, RI | 1 |
| Koval, LM | 1 |
| Kostyuk, PG | 2 |
| Morel, OE | 1 |
| Buvry, A | 1 |
| Le Corvoisier, P | 1 |
| Tual, L | 1 |
| Favret, F | 1 |
| León-Velarde, F | 1 |
| Crozatier, B | 1 |
| Richalet, JP | 2 |
| Höhne, C | 1 |
| Arntz, E | 1 |
| Krebs, MO | 1 |
| Boemke, W | 1 |
| Kaczmarczyk, G | 1 |
| Nagaoka, T | 1 |
| Morio, Y | 1 |
| Casanova, N | 1 |
| Bauer, N | 1 |
| Gebb, S | 1 |
| McMurtry, I | 1 |
| Oka, M | 2 |
| Peers, C | 4 |
| Green, KN | 1 |
| Boyle, JP | 1 |
| Arakawa, TK | 1 |
| Mlynarczyk, M | 1 |
| Kaushal, KM | 1 |
| Zhang, L | 1 |
| Ducsay, CA | 1 |
| Hodges, R | 1 |
| Barkehall-Thomas, A | 1 |
| Tippett, C | 1 |
| Brown, RC | 1 |
| Mark, KS | 1 |
| Egleton, RD | 1 |
| Davis, TP | 1 |
| Jiang, RG | 1 |
| Eyzaguirre, C | 1 |
| Hinton, M | 1 |
| Mellow, L | 1 |
| Halayko, AJ | 1 |
| Gutsol, A | 1 |
| Dakshinamurti, S | 1 |
| Broadley, KJ | 1 |
| Penson, PE | 1 |
| Yuan, SH | 1 |
| Guan, L | 1 |
| Ji, M | 1 |
| Soukhova-O'Hare, GK | 1 |
| Ortines, RV | 1 |
| Gu, Y | 1 |
| Nozdrachev, AD | 1 |
| Prabhu, SD | 1 |
| Gozal, D | 1 |
| Durand, JP | 1 |
| Guyard, MF | 1 |
| Ensel, J | 1 |
| Herment, C | 1 |
| Arrignon, J | 1 |
| Borde, J | 1 |
| Mitrofanoff, P | 1 |
| Dukes, ID | 1 |
| Vaughan Williams, EM | 1 |
| Rubin, LJ | 1 |
| Nayler, WG | 1 |
| Watanabe, S | 2 |
| Gaucher, LR | 1 |
| Payen, DM | 1 |
| Minsart, PJ | 1 |
| Peltier, PM | 1 |
| Ordronneau, JJ | 1 |
| Grolleau, JY | 1 |
| Michael, JR | 3 |
| Kennedy, TP | 3 |
| Fitzpatrick, S | 1 |
| Rosenstein, BJ | 1 |
| Sys, SU | 1 |
| Housmans, PR | 1 |
| Van Ocken, ER | 1 |
| Brutsaert, DL | 1 |
| Dickstein, PJ | 1 |
| Trindade, O | 1 |
| Goldberg, RN | 1 |
| Bancalari, E | 1 |
| Young, TE | 1 |
| Lundquist, LJ | 1 |
| Chesler, E | 3 |
| Weir, EK | 3 |
| Henry, PD | 1 |
| Wahl, AM | 1 |
| Cheung, JY | 1 |
| Leaf, A | 1 |
| Bonventre, JV | 1 |
| Rosenberger, LB | 1 |
| Jacobs, LW | 1 |
| Stanton, HC | 1 |
| Redding, GJ | 1 |
| Tuck, R | 1 |
| Escourrou, P | 2 |
| Stanbrook, HS | 1 |
| Morris, KG | 2 |
| McMurtry, IF | 2 |
| Higgins, TJ | 1 |
| Allsopp, D | 1 |
| Bailey, PJ | 1 |
| Naeije, R | 2 |
| Mélot, C | 2 |
| Mols, P | 2 |
| Hallemans, R | 2 |
| Durandy, Y | 1 |
| Pansard, Y | 1 |
| Mankikian, B | 1 |
| Dequirot, A | 1 |
| Kennedy, T | 1 |
| Summer, W | 1 |
| Simonneau, G | 1 |
| Duroux, P | 1 |
| Lockhart, A | 1 |
| Luk'ianova, LD | 1 |
| Kurlaev, SN | 1 |
| Crowley, MR | 1 |
| Fineman, JR | 1 |
| Soifer, SJ | 1 |
| Vannier, C | 1 |
| Croxton, TL | 1 |
| Farley, LS | 1 |
| Hirshman, CA | 1 |
| Shibata, S | 2 |
| Shindou, T | 1 |
| Tominaga, K | 1 |
| Li, MR | 1 |
| Chen, SC | 1 |
| Ma, G | 1 |
| Savineau, JP | 1 |
| Gonzalez de la Fuente, P | 1 |
| Marthan, R | 1 |
| Weiser, MC | 1 |
| Majack, RA | 1 |
| Tucker, A | 1 |
| Orton, EC | 1 |
| Salvaterra, CG | 1 |
| Goldman, WF | 1 |
| Planès, C | 1 |
| Friedlander, G | 1 |
| Loiseau, A | 1 |
| Amiel, C | 1 |
| Clerici, C | 1 |
| Barakat, M | 1 |
| du Souich, P | 1 |
| Varming, T | 1 |
| Drejer, J | 1 |
| Frandsen, A | 1 |
| Schousboe, A | 1 |
| Liu, SQ | 1 |
| Sharapov, VI | 1 |
| Grek, OR | 1 |
| Carpenter, E | 1 |
| Wyatt, CN | 1 |
| Hatton, CJ | 1 |
| Bee, D | 1 |
| Sanotskaia, NV | 1 |
| Matsievskiĭ, DD | 1 |
| Kurambaev, IaK | 1 |
| Safonov, VA | 1 |
| Blea, CW | 1 |
| Barnard, JM | 1 |
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6 reviews available for nifedipine and Anoxemia
| Article | Year |
|---|---|
Cardiovascular effects of vasodilator therapy for pulmonary arterial hypertension.
Topics: Cardiac Output; Echocardiography; Hemodynamics; Humans; Hydralazine; Hypertension, Pulmonary; Hypote | 1983 |
Calcium and cell death.
Topics: Adenosine Triphosphate; Animals; Calcium; Cell Survival; Coronary Disease; Heart Arrest, Induced; Hu | 1983 |
[New therapeutic agents and hypoxic pulmonary vasoconstriction].
Topics: Aminophylline; Anesthetics; Bronchodilator Agents; Humans; Hypoxia; Lung; Lung Diseases, Obstructive | 1983 |
[Who gets altitude sickness?].
Topics: Altitude Sickness; Blood Pressure; Disease Susceptibility; Humans; Hypoxia; Mountaineering; Nifedipi | 1992 |
Effects of angiotensin converting enzyme inhibitor and calcium channel blocker on normoxic and hypoxic pulmonary vascular tone in unanesthetized sheep.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; Female; Hemo | 1987 |
Therapeutic application of calcium-channel antagonists for pulmonary hypertension.
Topics: Animals; Calcium Channel Blockers; Cattle; Diltiazem; Hemodynamics; Humans; Hypertension, Pulmonary; | 1985 |
109 other studies available for nifedipine and Anoxemia
| Article | Year |
|---|---|
FDA approved L-type channel blocker Nifedipine reduces cell death in hypoxic A549 cells through modulation of mitochondrial calcium and superoxide generation.
Topics: A549 Cells; Calcium; Calcium Channel Blockers; Cell Death; COVID-19; Humans; Hypoxia; Nifedipine; SA | 2021 |
Ca
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Carotid Body; Cell | 2020 |
Effects of nifedipine and sildenafil on placental hemodynamics and gas exchange during fetal hypoxemia in a chronic sheep model.
Topics: Animals; Blood Pressure; Female; Hemodynamics; Hypoxia; Nifedipine; Placenta; Pregnancy; Sheep; Sild | 2020 |
Plateau hypoxia attenuates the metabolic activity of intestinal flora to enhance the bioavailability of nifedipine.
Topics: Animals; Biological Availability; Gastrointestinal Microbiome; Gastrointestinal Tract; Hypoxia; Male | 2018 |
CRHR2 (Corticotropin-Releasing Hormone Receptor 2) in the Nucleus of the Solitary Tract Contributes to Intermittent Hypoxia-Induced Hypertension.
Topics: Amphibian Proteins; Animals; Autonomic Nervous System; Calcium; Calcium Channel Blockers; Hypertensi | 2018 |
A protective role of Nox1/NADPH oxidase in a mouse model with hypoxia-induced bradycardia.
Topics: Action Potentials; Animals; Bradycardia; Calcium Channel Blockers; Disease Models, Animal; Electroca | 2015 |
Investigation of the Hepato-Protective Effects of Imdur in a Rat Model of Chronic Mountain Sickness.
Topics: Altitude Sickness; Animals; Biomarkers; Blood Pressure; C-Reactive Protein; Chronic Disease; Glutath | 2015 |
Amyloid Precursor Protein Protects Neuronal Network Function after Hypoxia via Control of Voltage-Gated Calcium Channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2016 |
[Chronic hypoxia increases intracellular Ca(2+) concentration and augments proliferation by enhancing store-operated Ca(2+) entry in pulmonary arterial smooth muscle cells].
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Hypoxia; Imidazoles; | 2016 |
Neuroprotective effects of mebudipine and dibudipine on cerebral oxygen-glucose deprivation/reperfusion injury.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Cell Death; Cell Survival; Cells, | 2009 |
Efficacy of olmesartan and nifedipine on recurrent hypoxia-induced left ventricular remodeling in diabetic mice.
Topics: Animals; Diabetes Mellitus, Type 2; Dietary Fats; Drug Therapy, Combination; Hypoxia; Imidazoles; Ma | 2010 |
Sinoatrial tissue of crucian carp heart has only negative contractile responses to autonomic agonists.
Topics: Acclimatization; Action Potentials; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; | 2010 |
Endoplasmic reticulum stress mediating downregulated StAR and 3-beta-HSD and low plasma testosterone caused by hypoxia is attenuated by CPU86017-RS and nifedipine.
Topics: 3-Hydroxysteroid Dehydrogenases; Animals; Berberine; Calcium; Calcium Channel Blockers; Down-Regulat | 2012 |
CPU86017-RS attenuate hypoxia-induced testicular dysfunction in mice by normalizing androgen biosynthesis genes and pro-inflammatory cytokines.
Topics: 3-Hydroxysteroid Dehydrogenases; Androgens; Animals; Berberine; Calcium Channel Blockers; Connexin 4 | 2012 |
Nifedipine inhibits hypoxia induced transvascular leakage through down regulation of NFkB.
Topics: Altitude Sickness; Animals; Calcium Channel Blockers; Capillary Permeability; Disease Models, Animal | 2012 |
Endogenous H2S is required for hypoxic sensing by carotid body glomus cells.
Topics: Alkynes; Animals; Cadmium Chloride; Calcium; Calcium Channel Blockers; Carotid Body; Catecholamines; | 2012 |
Intracellular mechanisms of hypoxia-induced calcium increase in rat sensory neurons.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Carbonyl Cyanide m-Ch | 2003 |
Effects of nifedipine-induced pulmonary vasodilatation on cardiac receptors and protein kinase C isoforms in the chronically hypoxic rat.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Chronic Disease; Hematocrit; Hemodynamics; | 2003 |
Nifedipine inhibits the hypoxia-induced decrease in plasma renin activity in conscious dogs.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Consciousness; Dogs; Female; Hypoxia; N | 2003 |
Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats.
Topics: Amides; Animals; Blood Pressure; Chromones; Enzyme Inhibitors; Hypertension, Pulmonary; Hypoxia; Ind | 2004 |
Amyloid peptide-mediated hypoxic regulation of Ca2+ channels in PC12 cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Calcium Channel Blockers; Calcium Channels; Calci | 2003 |
Long-term hypoxia alters calcium regulation in near-term ovine myometrium.
Topics: Animals; Calcium; Calcium Channel Blockers; Chronic Disease; Female; Gestational Age; Hypoxia; Myome | 2004 |
Maternal hypoxia associated with nifedipine for threatened preterm labour.
Topics: Adult; Dyspnea; Female; Heart Septal Defects, Ventricular; Humans; Hypoxia; Nifedipine; Obstetric La | 2004 |
Protection against hypoxia-induced blood-brain barrier disruption: changes in intracellular calcium.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Calcimycin; Calcium; Calcium Channel Blockers; Cattle; C | 2004 |
Calcium channels of cultured rat glomus cells in normoxia and acute hypoxia.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2005 |
Hypoxia induces hypersensitivity and hyperreactivity to thromboxane receptor agonist in neonatal pulmonary arterial myocytes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calci | 2006 |
Effects of hypoxia on the vasodilator activity of nifedipine and evidence of secondary pharmacological properties.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Cocaine; Dose-Response Relationship, Drug; Hypox | 2006 |
CPU0507, an endothelin receptor antagonist, improves rat hypoxic pulmonary artery hypertension and constriction in vivo and in vitro.
Topics: Animals; Antihypertensive Agents; Endothelin Receptor Antagonists; Heart; Hypertension, Pulmonary; H | 2006 |
Postnatal intermittent hypoxia and developmental programming of hypertension in spontaneously hypertensive rats: the role of reactive oxygen species and L-Ca2+ channels.
Topics: Animals; Antioxidants; Blood Pressure; Body Weight; Calcium Channel Blockers; Calcium Channels, L-Ty | 2008 |
[Postero-lateral hernia of the left diaphragmatic coupola in the newborn. Recovery from refractory hypoxemia with nifedipine].
Topics: Hernia, Diaphragmatic; Humans; Hypoxia; Infant, Newborn; Male; Nifedipine | 1983 |
Hypoxia-induced cardiac hypertrophy in rabbits treated with verapamil and nifedipine.
Topics: Animals; Cardiomegaly; Eating; Hypoxia; Nifedipine; Organ Size; Rabbits; Verapamil | 1983 |
Effects of nifedipine on pulmonary arterial hypertension in patients with respiratory insufficiency without acute failure.
Topics: Aged; Blood Pressure; Carbon Dioxide; Chronic Disease; Forced Expiratory Flow Rates; Heart Rate; Hum | 1984 |
Nifedipine inhibits hypoxic pulmonary vasoconstriction during rest and exercise in patients with cystic fibrosis and cor pulmonale.
Topics: Adult; Combined Modality Therapy; Cystic Fibrosis; Hemodynamics; Humans; Hypoxia; Lung; Male; Nifedi | 1984 |
Mechanisms of hypoxia-induced decrease of load dependence of relaxation in cat papillary muscle.
Topics: Animals; Biomechanical Phenomena; Calcium; Cats; Hypoxia; In Vitro Techniques; Myocardial Contractio | 1984 |
The effect of calcium antagonists on hypoxic pulmonary hypertension in the piglet.
Topics: Animals; Animals, Newborn; Cardiac Output; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary W | 1984 |
Comparative effects of nifedipine, verapamil, and diltiazem on experimental pulmonary hypertension.
Topics: Animals; Benzazepines; Blood Pressure; Cardiac Output; Diltiazem; Dinoprost; Dogs; Dose-Response Rel | 1983 |
Diltiazem and nitrendipine suppress hypoxic contracture in quiescent ventricular myocardium.
Topics: Animals; Benzazepines; Calcium Channel Blockers; Diltiazem; Hypoxia; In Vitro Techniques; Male; Myoc | 1983 |
Mechanism of protection by verapamil and nifedipine from anoxic injury in isolated cardiac myocytes.
Topics: Animals; Biomechanical Phenomena; Calcium; Hypoxia; Myocardial Contraction; Myocardium; Nifedipine; | 1984 |
Evaluation of cardiac anoxia and ischemia models in the rat using calcium antagonists.
Topics: Adenine Nucleotides; Animals; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Corona | 1984 |
Nifedipine attenuates acute hypoxic pulmonary vasoconstriction in awake piglets.
Topics: Animals; Animals, Newborn; Hemodynamics; Hypoxia; Lung; Nifedipine; Swine; Vasoconstriction | 1984 |
Prevention and reversal of hypoxic pulmonary hypertension by calcium antagonists.
Topics: Animals; Dimethyl Sulfoxide; Hydralazine; Hypertension, Pulmonary; Hypoxia; Male; Nifedipine; Pulmon | 1984 |
The effect of extracellular calcium concentration and Ca-antagonist drugs on enzyme release and lactate production by anoxic heart cell cultures.
Topics: Animals; Calcium; Cells, Cultured; Glucose; Heart; Hypoxia; L-Lactate Dehydrogenase; Lactates; Manni | 1980 |
Effects of vasodilators on hypoxic pulmonary vasoconstriction in normal man.
Topics: Adult; Female; Hemodynamics; Humans; Hypoxia; Male; Nifedipine; Nitroglycerin; Nitroprusside; Oxygen | 1982 |
[Comparative effects of tolazoline and nifedipine on hypoxic pulmonary arterial hypertension in the dog (author's transl)].
Topics: Animals; Dogs; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary Circulation; Pyridines; Tolaz | 1982 |
Inhibition of hypoxic pulmonary vasoconstriction by nifedipine.
Topics: Animals; Calcium Channel Blockers; Depression, Chemical; Dose-Response Relationship, Drug; Hypertens | 1982 |
Inhibition of hypoxic pulmonary vasoconstriction by nifedipine.
Topics: Aged; Bronchitis; Depression, Chemical; Hemodynamics; Humans; Hypoxia; Middle Aged; Nifedipine; Oxyg | 1981 |
[Effect of nifedipine and ruthenium red on the contractile function and oxidative metabolism of the myocardium].
Topics: Animals; Calcium; Hypoxia; Immunity, Innate; Male; Myocardial Contraction; Myocardium; Nifedipine; O | 1993 |
HA1004, an intracellular calcium antagonist, selectively attenuates pulmonary hypertension in newborn lambs.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Calci | 1994 |
Inhibition of dihydropyridine-sensitive calcium entry in hypoxic relaxation of airway smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Calcium channel blockers improve hypoxia/hypoglycemia-induced impairment of rat hippocampal 2-deoxyglucose uptake in vitro after ethanol withdrawal.
Topics: Animals; Calcium Channel Blockers; Deoxyglucose; Dizocilpine Maleate; Dose-Response Relationship, Dr | 1995 |
[Comparative effects of calcium channel blockers and L-arginine on chronic intermittent hypoxic pulmonary hypertension in rats].
Topics: Animals; Arginine; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Male; Nifedipin | 1994 |
Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.
Topics: Aged; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Glyburide; Humans; Hypoxia; In Vi | 1995 |
Static tension is associated with increased smooth muscle cell DNA synthesis in rat pulmonary arteries.
Topics: Animals; Blood Pressure; Bromodeoxyuridine; Cell Division; DNA; Endothelium, Vascular; Hypertension, | 1995 |
NIP-121 is more effective than nifedipine in acutely reversing chronic pulmonary hypertension.
Topics: Altitude; Animals; Chronic Disease; Glyburide; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; | 1993 |
Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes.
Topics: Acute Disease; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cu | 1993 |
Inhibition of Na-K-ATPase activity after prolonged hypoxia in an alveolar epithelial cell line.
Topics: Adenosine Triphosphate; Animals; Cell Line, Transformed; Culture Media, Conditioned; Epithelium; Hyp | 1996 |
Effect of nifedipine on the elimination of theophylline in the rabbit subjected to hypoxia or to an inflammatory reaction.
Topics: Animals; Area Under Curve; Bronchodilator Agents; Calcium Channel Blockers; Cytochrome P-450 Enzyme | 1996 |
Characterization of a chemical anoxia model in cerebellar granule neurons using sodium azide: protection by nifedipine and MK-801.
Topics: Animals; Azides; Brain Ischemia; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Dose-Response Rel | 1996 |
Alterations in structure of elastic laminae of rat pulmonary arteries in hypoxic hypertension.
Topics: Animals; Calcium Channel Blockers; Cardiac Output; Elasticity; Hypertension; Hypoxia; Male; Microsco | 1996 |
[Activity of liver monooxygenase system in rats with low and high resistance to hypoxia].
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Cytochromes b5; Diazepam; Hypoxia; Male; Micros | 1996 |
Ca2+ channel currents in type I carotid body cells from normoxic and chronically hypoxic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1996 |
[Effect of calcium and its antagonists on hemodynamics and respiration].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Calcium Chloride; Cardiac Output; Cats; Cerebrova | 1996 |
Effect of nifedipine on fetal and maternal hemodynamics and blood gases in the pregnant ewe.
Topics: Acidosis; Animals; Bicarbonates; Female; Fetal Blood; Fetal Diseases; Fetus; Half-Life; Hemodynamics | 1997 |
Pulmonary hypertension in high-altitude chronic hypoxia: response to nifedipine.
Topics: Adolescent; Adult; Altitude; Blood Pressure; Calcium Channel Blockers; Echocardiography, Doppler; Fe | 1998 |
High-threshold calcium channel activity in rat hippocampal neurones during hypoxia.
Topics: Animals; Animals, Newborn; Cadmium; Calcium; Calcium Channel Blockers; Calcium Channels; Hippocampus | 1999 |
Acid-evoked quantal catecholamine secretion from rat phaeochromocytoma cells and its interaction with hypoxia-evoked secretion.
Topics: Animals; Cadmium; Calcium; Catecholamines; Exocytosis; Hydrogen-Ion Concentration; Hypoxia; Nifedipi | 1999 |
Nifedipine inhibits pulmonary hypertension but does not prevent decreased lung eNOS in hypoxic newborn pigs.
Topics: Acetylcholine; Animals; Animals, Newborn; Blood Pressure; Calcium Channel Blockers; Hypertension, Pu | 1999 |
Inhaled nitric oxide and nifedipine have similar effects on lung cGMP levels in rats.
Topics: 6-Ketoprostaglandin F1 alpha; Administration, Inhalation; Animals; Bronchodilator Agents; Cyclic AMP | 1999 |
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; | 2000 |
Human umbilical vein endothelial cells (HUVECs) show Ca(2+) mobilization as well as Ca(2+) influx upon hypoxia.
Topics: Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Egtazic Acid; Endothelium, Vas | 2000 |
Coronary vasomotor disorders during hypoxia-reoxygenation: do calcium channel blockers play a protective role?
Topics: Adenosine Diphosphate; Animals; Calcium Channel Blockers; Coronary Circulation; Coronary Vasospasm; | 2000 |
L-type Ca(2+) channels, resting [Ca(2+)](i), and ET-1-induced responses in chronically hypoxic pulmonary myocytes.
Topics: Animals; Calcium; Calcium Channels, L-Type; Cells, Cultured; Endothelin-1; Hypoxia; Male; Muscle, Sm | 2000 |
Gadolinium prevents stretch-mediated contractile dysfunction in isolated papillary muscles.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Gadolinium; Guinea Pi | 2001 |
Sites and ionic mechanisms of hypoxic vasoconstriction in frog skin.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 2001 |
[Experimental study on effect of altitude xishi capsule in treating oleic acid induced lung injury in acute hypoxia rats].
Topics: Animals; Dexamethasone; Disease Models, Animal; Drug Combinations; Hypoxia; Male; Nifedipine; Oleic | 1998 |
[The effect of increased extracellular calcium concentration on the hypoxic and pharmacologic hyperemia of skeletal muscle].
Topics: Adenosine; Animals; Calcium; Dogs; Hyperemia; Hypoxia; Muscles; Nifedipine; Regional Blood Flow; Sti | 1975 |
[Effects of calcium blockers on the performance of left and right ventricles during acute hypoxia].
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Dogs; Hemodynamics; Hypoxia; Male; Nif | 1992 |
[The effects of calcium antagonists on ventilation-perfusion mismatching in the canine lung].
Topics: Animals; Calcium Channel Blockers; Diltiazem; Dogs; Hypoxia; Models, Biological; Nifedipine; Oxygen; | 1992 |
Diverse effects of calcium channel blockers on skeletal muscle glucose transport.
Topics: 3-O-Methylglucose; Animals; Biological Transport; Calcium Channel Blockers; Diltiazem; Dose-Response | 1992 |
Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1990 |
[Verapamil and nifedipine limit hemodynamic changes in pulmonary circulation in rats with hypoxia].
Topics: Animals; Antihypertensive Agents; Blood Pressure; Depression, Chemical; Disease Models, Animal; Hype | 1991 |
Vanadate potentiates hypoxic pulmonary vasoconstriction.
Topics: Animals; Blood Pressure; Carbamates; Catalase; Cyanides; Hypoxia; Lung; Male; Nifedipine; Oxygen; Pe | 1991 |
Marked decrease in arterial oxygen tension associated with continuous intravenous nifedipine administration.
Topics: Arteries; Depression, Chemical; Female; Humans; Hypoxia; Infusions, Intravenous; Intraoperative Comp | 1991 |
Work and contraction curves of atrial muscle preparations during anoxia and reoxygenation influenced by cardio-tonic and cardio-depressive drugs.
Topics: Adaptation, Physiological; Animals; Depression, Chemical; Guinea Pigs; Hypoxia; In Vitro Techniques; | 1991 |
Acute effects on pulmonary haemodynamics of nifedipine in adult patients with cystic fibrosis.
Topics: Adult; Blood Pressure; Cystic Fibrosis; Hemodynamics; Humans; Hypoxia; Nifedipine; Pulmonary Alveoli | 1990 |
Pulmonary vascular tone is increased by a voltage-dependent calcium channel potentiator.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1986 |
Enhanced hypoxic pulmonary vasoconstriction in hypertension.
Topics: Adrenergic alpha-Antagonists; Calcium Channel Blockers; Humans; Hypotension; Hypoxia; Male; Middle A | 1989 |
Nifedipine for high altitude pulmonary oedema.
Topics: Acute Disease; Administration, Sublingual; Adult; Altitude Sickness; Delayed-Action Preparations; Ec | 1989 |
Pulmonary vascular responses to hypercalcemia and hypocalcemia in the dog.
Topics: Animals; Blood Pressure; Dogs; Female; Hypercalcemia; Hypocalcemia; Hypoxia; In Vitro Techniques; Ma | 1989 |
[Efficacy of nifedipine on refractory hypoxemia associated with diaphragmatic hernia in the newborn infant. Apropos of a case].
Topics: Drug Evaluation; Hernia, Diaphragmatic; Hernias, Diaphragmatic, Congenital; Humans; Hypertension, Pu | 1989 |
Comparative effects of oxygen, nifedipine and ketanserin in hypoxic pulmonary hypertension.
Topics: Adult; Carbon Dioxide; Cardiac Output; Female; Heart Rate; Humans; Hypertension, Pulmonary; Hypoxia; | 1985 |
Nitrendipine attenuates the pulmonary vascular remodeling and right ventricular hypertrophy caused by intermittent hypoxia in rats.
Topics: Animals; Cardiomegaly; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy; Hypoxia; Male; Muscle | 1986 |
[Influence of antianginal drugs on Lypressin induced T-wave enhancement in the electrocardiogram of the rat].
Topics: Administration, Oral; Angina Pectoris; Animals; Coronary Vasospasm; Electrocardiography; Hypoxia; Is | 1986 |
[Effects of nifedipine on myocardial contractility and pulmonary hypertension in hypoxic rats].
Topics: Animals; Blood Pressure; Hematocrit; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; Myocardia | 1987 |
Effects of nitroglycerin, dipyridamole, nifedipine, verapamil and diltiazem on canine coronary arterial rings contracted with 5-hydroxytryptamine and anoxia.
Topics: Animals; Arteries; Calcium; Calcium Channel Blockers; Coronary Vessels; Diltiazem; Dipyridamole; Dog | 1986 |
Nifedipine increases oxygen saturation level of myoglobin in the rat heart during hypoxia.
Topics: Animals; Dipyridamole; Heart; Hypoxia; Male; Myocardium; Myoglobin; Nifedipine; Nitroglycerin; Rats; | 1986 |
[Effect of a single dose of nifedipine on hemodynamic parameters of pulmonary circulation and left-ventricular function in patients with hypoxic pulmonary hypertension].
Topics: Administration, Sublingual; Adult; Aged; Female; Heart Ventricles; Hemodynamics; Humans; Hypertensio | 1988 |
[Nifedipine in the treatment of pulmonary hypertension. II--Hypoxic pulmonary hypertension].
Topics: Animals; Humans; Hypertension, Pulmonary; Hypoxia; Nifedipine; Pulmonary Artery; Rats; Vascular Resi | 1986 |
[Effects of nifedipine on hypoxic pulmonary vasoconstriction].
Topics: Animals; Dogs; Hypoxia; Male; Nifedipine; Pulmonary Artery; Pulmonary Circulation; Vasoconstriction | 1987 |
Hypoxic pulmonary vasoconstriction and pulmonary gas exchange in normal man.
Topics: Adult; Blood Pressure; Cardiac Output; Female; Humans; Hypoxia; Male; Middle Aged; Nifedipine; Pulmo | 1987 |
The in vivo contour plot. An improved representation of stimulus experiments.
Topics: Animals; Coronary Circulation; Heart; Hypoxia; Ischemia; Liver; Magnetic Resonance Spectroscopy; Mic | 1987 |
Effects of calcium, calcium entry blockers and calmodulin inhibitors on atrioventricular conduction disturbances induced by hypoxia.
Topics: Animals; Atrioventricular Node; Calcium; Calcium Channel Blockers; Calmodulin; Chlorpromazine; Heart | 1986 |
Beneficial effects of calcium channel blockers and calmodulin binding drugs on in vitro renal cell anoxia.
Topics: Animals; Calcium Channel Blockers; Calmodulin; Cell Survival; Cells, Cultured; Hypoxia; Isomerism; N | 1986 |
Effects of dopamine and nifedipine infusions on the pulmonary circulation of the lamb.
Topics: Acidosis; Animals; Blood Pressure; Cardiac Output; Dopamine; Hypoxia; Nifedipine; Pulmonary Circulat | 1986 |
A case of high-altitude pulmonary edema treated with nifedipine.
Topics: Altitude Sickness; Emergencies; Humans; Hypoxia; Male; Nifedipine; Pulmonary Edema | 1987 |
Comparative effects of nisoldipine, nifedipine and bepridil on experimental pulmonary hypertension.
Topics: Animals; Bepridil; Blood Gas Analysis; Calcium Channel Blockers; Dinoprost; Dogs; Female; Hemodynami | 1985 |
Improvement in relaxation by nifedipine in hypoxic isometric cat papillary muscle.
Topics: Animals; Cats; Hypoxia; Myocardial Contraction; Nifedipine; Oxygen; Time Factors | 1986 |
Hemodynamic effects of nifedipine in normoxic and hypoxic newborn lambs.
Topics: Analysis of Variance; Animals; Animals, Newborn; Blood Gas Analysis; Blood Pressure; Disease Models, | 1985 |
Use of calcium channel blockers in hypoxic lung disease.
Topics: Calcium Channel Blockers; Humans; Hypoxia; Lung Diseases; Lung Diseases, Obstructive; Nifedipine; Ox | 1985 |