nifedipine has been researched along with Alloxan Diabetes in 64 studies
Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Time-dependent effects of alpha-lipoic acid/nifedipine/glimepiride combination on diabetic neuropathies were investigated in rats." | 8.12 | Diurnal efficacy of alpha-lipoic acid/nifedipine/glimepiride combination mitigates diabetic neuropathies in rats. ( Anafi, SB; Bisalla, M; Olurishe, TO; Oraebosi, MI, 2022) |
| " The present study was undertaken to examine the efficacy of nifedipine, a dihydropyridine CCB, on obesity, glucose intolerance and vascular endothelial dysfunction in db/db mice (a mouse model of obesity and type 2 diabetes)." | 7.76 | Nifedipine prevents vascular endothelial dysfunction in a mouse model of obesity and type 2 diabetes, by improving eNOS dysfunction and dephosphorylation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yasuda, O, 2010) |
| "To study if the endogenous renin-angiotensin system affects diabetic retinal leukostasis, rats with streptozotocin-induced diabetes were treated with an ACE inhibitor (ramipril), an angiotensin II AT(1) receptor antagonist (losartan) and the Ca channel blocker, (nifedipine)." | 7.73 | Role of angiotensin II in retinal leukostasis in the diabetic rat. ( Chen, P; Dahl, D; Edwards, PA; Fenstermacher, JD; Guo, M; Scicli, AG; Scicli, GM, 2006) |
| " Dosage of nifedipine or efonidipine was chosen after preliminary studies demonstrated that it showed moderate antihypertensive action (more than a 20% decrease in systemic blood pressure after treatment)." | 5.30 | Effects of the antihypertensive drug nifedipine on albuminuria and renal histopathology in young spontaneously hypertensive rats with diabetes. ( Kaneko, S; Shou, I; Takeda, M; Takizawa, H; Tomino, Y, 1999) |
| "Time-dependent effects of alpha-lipoic acid/nifedipine/glimepiride combination on diabetic neuropathies were investigated in rats." | 4.12 | Diurnal efficacy of alpha-lipoic acid/nifedipine/glimepiride combination mitigates diabetic neuropathies in rats. ( Anafi, SB; Bisalla, M; Olurishe, TO; Oraebosi, MI, 2022) |
| "The intraislet insulin hypothesis proposes that glucagon secretion during hypoglycemia is triggered by a decrease in intraislet insulin secretion." | 3.76 | ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation. ( Bryan, J; Harmon, JS; Oseid, EA; Robertson, RP; Slucca, M, 2010) |
| " The present study was undertaken to examine the efficacy of nifedipine, a dihydropyridine CCB, on obesity, glucose intolerance and vascular endothelial dysfunction in db/db mice (a mouse model of obesity and type 2 diabetes)." | 3.76 | Nifedipine prevents vascular endothelial dysfunction in a mouse model of obesity and type 2 diabetes, by improving eNOS dysfunction and dephosphorylation. ( Dong, YF; Fukuda, M; Kataoka, K; Kim-Mitsuyama, S; Nakamura, T; Nako, H; Ogawa, H; Tokutomi, Y; Yamamoto, E; Yasuda, O, 2010) |
| "To study if the endogenous renin-angiotensin system affects diabetic retinal leukostasis, rats with streptozotocin-induced diabetes were treated with an ACE inhibitor (ramipril), an angiotensin II AT(1) receptor antagonist (losartan) and the Ca channel blocker, (nifedipine)." | 3.73 | Role of angiotensin II in retinal leukostasis in the diabetic rat. ( Chen, P; Dahl, D; Edwards, PA; Fenstermacher, JD; Guo, M; Scicli, AG; Scicli, GM, 2006) |
| " Dosage of nifedipine or efonidipine was chosen after preliminary studies demonstrated that it showed moderate antihypertensive action (more than a 20% decrease in systemic blood pressure after treatment)." | 1.30 | Effects of the antihypertensive drug nifedipine on albuminuria and renal histopathology in young spontaneously hypertensive rats with diabetes. ( Kaneko, S; Shou, I; Takeda, M; Takizawa, H; Tomino, Y, 1999) |
| "Nifedipine treatment significantly prevented STZ-induced increase in cholesterol and triglyceride levels." | 1.29 | Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats. ( Bangaru, RA; Gandhi, TP; Goyal, RK; Satia, MC; Shah, TS, 1995) |
| "Nifedipine treatment did not alter these parameters of controls, but decreased the heart weight and heart weight-to-body weight ratio of diabetic rats without affecting the body weight." | 1.29 | Impaired mechanical response to calcium of diabetic rat hearts: reversal by nifedipine treatment. ( Higa, S; Murakami, K; Nagamine, F; Shimabukuro, M; Shinzato, T; Takasu, N, 1995) |
| "Nifedipine treatment completely reversed diabetes-induced prolongation in both time-to-peak tension and time-to-90% relaxation." | 1.29 | Influence of calcium channel blocker treatment on the mechanical properties of diabetic rat myocardium. ( Brown, RA; Lee, MM; Savage, AO; Sundareson, AM; Woodbury, DJ, 1996) |
| "Hypertension was associated with enhanced pressor response, whereas the diabetic state counteracted this effect." | 1.29 | Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats. ( Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Nifedipine treatment had no significant effect on conduction velocity in non-diabetic rats." | 1.28 | The effect of the calcium antagonist nifedipine on peripheral nerve function in streptozotocin-diabetic rats. ( Cameron, NE; Cotter, MA; Robertson, S, 1992) |
| "Nifedipine was more potent in inhibiting the K+ response in diabetic carotid artery than in the controls." | 1.27 | Effect of chronic experimental diabetes on vascular smooth muscle function in rabbit carotid artery. ( Agrawal, DK; Bhimji, S; McNeill, JH, 1987) |
| "Nifedipine was more potent in inhibiting the contraction to K+ and serotonin in WKY diabetic arteries as compared with WKY controls." | 1.27 | Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery. ( Agrawal, DK; McNeill, JH, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (9.38) | 18.7374 |
| 1990's | 32 (50.00) | 18.2507 |
| 2000's | 12 (18.75) | 29.6817 |
| 2010's | 9 (14.06) | 24.3611 |
| 2020's | 5 (7.81) | 2.80 |
| Authors | Studies |
|---|---|
| Bass, JY | 1 |
| Caravella, JA | 1 |
| Chen, L | 1 |
| Creech, KL | 1 |
| Deaton, DN | 1 |
| Madauss, KP | 1 |
| Marr, HB | 1 |
| McFadyen, RB | 1 |
| Miller, AB | 1 |
| Mills, WY | 1 |
| Navas, F | 1 |
| Parks, DJ | 1 |
| Smalley, TL | 1 |
| Spearing, PK | 1 |
| Todd, D | 1 |
| Williams, SP | 1 |
| Wisely, GB | 1 |
| Oraebosi, MI | 2 |
| Olurishe, TO | 2 |
| Anafi, SB | 2 |
| Bisalla, M | 2 |
| Peng, C | 1 |
| Yang, LJ | 1 |
| Zhang, C | 1 |
| Jiang, Y | 1 |
| Shang, LW | 1 |
| He, JB | 1 |
| Zhou, ZW | 1 |
| Tao, X | 1 |
| Tie, L | 1 |
| Chen, AF | 1 |
| Xie, HH | 1 |
| Liu, L | 1 |
| Yang, H | 1 |
| Kuang, SJ | 1 |
| Zhang, L | 1 |
| Zhou, MY | 1 |
| Zeng, P | 1 |
| Zhang, MZ | 1 |
| Rao, F | 1 |
| Zhou, ZL | 1 |
| Deng, CY | 1 |
| Yilmaz-Oral, D | 1 |
| Onder, A | 1 |
| Gur, S | 1 |
| Carbonell-Barrachina, ÁA | 1 |
| Kaya-Sezginer, E | 1 |
| Oztekin, CV | 1 |
| Zor, M | 1 |
| Ma, Z | 1 |
| Moruzzi, N | 1 |
| Catrina, SB | 1 |
| Hals, I | 1 |
| Oberholzer, J | 1 |
| Grill, V | 1 |
| Björklund, A | 1 |
| Zhang, B | 1 |
| He, K | 1 |
| Chen, W | 1 |
| Cheng, X | 1 |
| Cui, H | 1 |
| Zhong, W | 1 |
| Li, S | 1 |
| Wang, L | 1 |
| Jain, S | 1 |
| Sharma, BM | 1 |
| Sharma, B | 1 |
| Slucca, M | 1 |
| Harmon, JS | 1 |
| Oseid, EA | 1 |
| Bryan, J | 1 |
| Robertson, RP | 1 |
| Wu, C | 1 |
| Li, Y | 1 |
| Chen, Y | 1 |
| Lao, X | 1 |
| Sheng, L | 1 |
| Dai, R | 1 |
| Meng, W | 1 |
| Deng, Y | 1 |
| Sepehr-Ara, L | 1 |
| Sepehr-Ara, M | 1 |
| Mahmoudian, M | 2 |
| Yamamoto, E | 1 |
| Nakamura, T | 1 |
| Kataoka, K | 1 |
| Tokutomi, Y | 1 |
| Dong, YF | 1 |
| Fukuda, M | 1 |
| Nako, H | 1 |
| Yasuda, O | 1 |
| Ogawa, H | 1 |
| Kim-Mitsuyama, S | 1 |
| Leiria, LO | 1 |
| Mónica, FZ | 1 |
| Carvalho, FD | 1 |
| Claudino, MA | 1 |
| Franco-Penteado, CF | 1 |
| Schenka, A | 1 |
| Grant, AD | 1 |
| De Nucci, G | 1 |
| Antunes, E | 1 |
| Chan, P | 1 |
| Wong, KL | 1 |
| Liu, IM | 1 |
| Tzeng, TF | 1 |
| Yang, TL | 1 |
| Cheng, JT | 1 |
| Forrest, A | 2 |
| Parsons, M | 2 |
| Kobayashi, S | 1 |
| Fukuta, M | 1 |
| Suzuki, M | 1 |
| Tsuneki, H | 1 |
| Kimura, I | 1 |
| Molleman, A | 1 |
| Svíglerová, J | 1 |
| Kuncová, J | 1 |
| Stengl, M | 1 |
| Chen, P | 1 |
| Scicli, GM | 1 |
| Guo, M | 1 |
| Fenstermacher, JD | 1 |
| Dahl, D | 1 |
| Edwards, PA | 1 |
| Scicli, AG | 1 |
| Kametaka, S | 1 |
| Kasahara, T | 1 |
| Ueo, M | 1 |
| Takenaka, M | 1 |
| Saito, M | 1 |
| Sakamoto, K | 1 |
| Nakahara, T | 1 |
| Ishii, K | 1 |
| Scarborough, NL | 1 |
| Carrier, GO | 1 |
| Roth, DM | 1 |
| Foster, KA | 1 |
| Lefer, AM | 1 |
| Pijl, AJ | 1 |
| Hendriks, MG | 1 |
| Kam, KL | 2 |
| Pfaffendorf, M | 3 |
| van Zwieten, PA | 5 |
| Shah, TS | 1 |
| Satia, MC | 1 |
| Gandhi, TP | 1 |
| Bangaru, RA | 1 |
| Goyal, RK | 1 |
| Petitjean, P | 1 |
| Vloemans, M | 1 |
| Barthelmebs, M | 1 |
| Stephan, D | 1 |
| Grima, M | 1 |
| Jund, A | 1 |
| Imbs, JL | 1 |
| Orie, NN | 1 |
| Aloamaka, CP | 1 |
| Heijnis, JB | 2 |
| Kaymaz, AA | 1 |
| Tan, H | 1 |
| Altuğ, T | 1 |
| Büyükdevrim, AS | 1 |
| Shimabukuro, M | 2 |
| Shinzato, T | 2 |
| Higa, S | 2 |
| Nagamine, F | 2 |
| Murakami, K | 2 |
| Takasu, N | 2 |
| Weber, LP | 1 |
| Chow, WL | 1 |
| Abebe, W | 2 |
| MacLeod, KM | 2 |
| Brown, RA | 2 |
| Sundareson, AM | 2 |
| Lee, MM | 2 |
| Savage, AO | 2 |
| Woodbury, DJ | 1 |
| Beenen, OH | 1 |
| Mathy, MJ | 2 |
| Behnaz, F | 1 |
| Rezaei, E | 1 |
| Bouskela, E | 1 |
| Cyrino, FZ | 1 |
| Conde, CM | 1 |
| Garcia, AA | 1 |
| Kawasaki, H | 3 |
| Iwai, T | 1 |
| Irlbeck, M | 1 |
| Zimmer, HG | 1 |
| Kaneko, S | 1 |
| Takizawa, H | 1 |
| Takeda, M | 1 |
| Shou, I | 1 |
| Tomino, Y | 1 |
| Hattori, Y | 2 |
| Kanno, M | 2 |
| Matsuda, N | 1 |
| Sato, A | 1 |
| Watanuki, S | 1 |
| Tomioka, H | 1 |
| Voitenko, NV | 1 |
| Kruglikov, IA | 1 |
| Kostyuk, EP | 1 |
| Kostyuk, PG | 1 |
| Yamamoto, T | 1 |
| Tomura, Y | 1 |
| Tanaka, H | 1 |
| Kajiya, F | 1 |
| Misurski, DA | 1 |
| Hopfner, RL | 1 |
| Gopalakrishnan, V | 1 |
| Kostyuk, E | 1 |
| Voitenko, N | 1 |
| Kruglikov, I | 1 |
| Shmigol, A | 1 |
| Shishkin, V | 1 |
| Efimov, A | 1 |
| Kostyuk, P | 1 |
| Belis, JA | 2 |
| Curley, RM | 2 |
| Murty, VN | 2 |
| Wagner, CH | 2 |
| Winter, SJ | 2 |
| Rohner, TJ | 2 |
| Anderson, S | 1 |
| Rennke, HG | 1 |
| Brenner, BM | 1 |
| Robertson, S | 1 |
| Cameron, NE | 1 |
| Cotter, MA | 1 |
| Longhurst, PA | 1 |
| Brotcke, TP | 1 |
| Leggett, RE | 1 |
| Levin, RM | 1 |
| Eckel, J | 1 |
| Gerlach-Eskuchen, E | 1 |
| Reinauer, H | 1 |
| Luheshi, GN | 1 |
| Zar, MA | 1 |
| Inazu, M | 1 |
| Sakai, Y | 1 |
| Homma, I | 1 |
| Sarubbi, D | 1 |
| Quilley, J | 1 |
| Solomon, SS | 1 |
| Chiang, TM | 1 |
| Palazzolo, MR | 1 |
| Sunaga, K | 1 |
| Ogihara, M | 1 |
| Agrawal, DK | 3 |
| Bhimji, S | 1 |
| McNeill, JH | 3 |
| Sato, T | 1 |
| Nara, Y | 1 |
| Note, S | 1 |
| Yamori, Y | 1 |
64 other studies available for nifedipine and Alloxan Diabetes
| Article | Year |
|---|---|
Conformationally constrained farnesoid X receptor (FXR) agonists: heteroaryl replacements of the naphthalene.
Topics: Animals; Binding Sites; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Dogs | 2011 |
Diurnal efficacy of alpha-lipoic acid/nifedipine/glimepiride combination mitigates diabetic neuropathies in rats.
Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Nifedipine; Rats; Sul | 2022 |
Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Endothelial Progenitor Cells; Glucose; Is | 2023 |
Contribution of calcium dysregulation to impaired coronary artery contraction in Zucker diabetic fatty rats.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Calcium Channe | 2023 |
The beneficial effect of clove essential oil and its major component, eugenol, on erectile function in diabetic rats.
Topics: Animals; Clove Oil; Diabetes Mellitus, Experimental; Erectile Dysfunction; Eugenol; Glyburide; In Vi | 2020 |
Chronopharmacology of the alpha-lipoic acid/nifedipine/glimepiride combination in the amelioration of retinopathy in rats.
Topics: Animals; Antioxidants; Circadian Rhythm; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Nife | 2021 |
Preconditioning with associated blocking of Ca2+ inflow alleviates hypoxia-induced damage to pancreatic β-cells.
Topics: AMP-Activated Protein Kinases; Animals; Calcium; Calcium Channel Blockers; Cell Hypoxia; Cells, Cult | 2013 |
Alagebrium (ALT-711) improves the anti-hypertensive efficacy of nifedipine in diabetic-hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Drug Therapy, Com | 2014 |
Calcium Channel Blockade and Peroxisome Proliferator Activated Receptor γ Agonism Diminish Cognitive Loss and Preserve Endothelial Function During Diabetes Mellitus.
Topics: Animals; Attention; Blood-Brain Barrier; Brain; Calcium Channel Blockers; Calcium Channels; Capillar | 2016 |
ATP-sensitive K+ channel mediates the zinc switch-off signal for glucagon response during glucose deprivation.
Topics: Animals; Calcium Channels; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mell | 2010 |
Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active faction.
Topics: Animals; Blood Glucose; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; Glucose Toleranc | 2011 |
Effect of the two new calcium channel blockers mebudipine and dibudipine in comparison to amlodipine on vascular flow of isolated kidney of diabetic rat.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diab | 2010 |
Nifedipine prevents vascular endothelial dysfunction in a mouse model of obesity and type 2 diabetes, by improving eNOS dysfunction and dephosphorylation.
Topics: Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Dia | 2010 |
Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+ channels.
Topics: Amides; Animals; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Carbachol; Ch | 2011 |
Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Calcium Ch | 2003 |
The enhanced spontaneous activity of the diabetic colon is not the consequence of impaired inhibitory control mechanisms.
Topics: Animals; Antioxidants; Blood Glucose; Blotting, Western; Citrulline; Colon; Diabetes Mellitus, Exper | 2003 |
Inhibitory effect of nifedipine on tumor necrosis factor alpha-induced neovascularization in cultured choroidal explants of streptozotocin-diabetic rat.
Topics: Animals; Choroid; Choroidal Neovascularization; Diabetes Mellitus, Experimental; Male; Nifedipine; O | 2005 |
The responses to manipulation of extracellular and intracellular calcium are altered in the streptozotocin-diabetic rat colon and ileum.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2005 |
Negative inotropic effect of insulin in papillary muscles from control and diabetic rats.
Topics: Animals; Blood Glucose; Calcium Channel Blockers; Calcium Channels, L-Type; Diabetes Mellitus, Exper | 2005 |
Role of angiotensin II in retinal leukostasis in the diabetic rat.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; A | 2006 |
Effect of nifedipine on severe experimental cataract in diabetic rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Cataract; Diabetes Me | 2008 |
Nifedipine and alpha adrenoceptors in rat aorta. II. Role of extracellular calcium in enhanced alpha-2 adrenoceptor-mediated contraction in diabetes.
Topics: Animals; Aorta; Calcium; Clonidine; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dru | 1984 |
Coronary vascular responsiveness to non-eicosanoid vasoconstrictors in the perfused diabetic rat heart.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1984 |
Antiischemic effects of nifedipine in isolated working heart preparations of healthy, diabetic, and hypertensive rats.
Topics: Animals; Blood Glucose; Blood Pressure; Body Weight; Cardiac Output; Coronary Circulation; Diabetes | 1994 |
Effects of chronic nifedipine treatment on streptozotocin-induced diabetic rats.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Bradycardia; | 1995 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, | 1994 |
Short-term effects of quinapril and nifedipine on early renal changes in streptozotocin-induced diabetes in rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Carbon Dioxide; Diabe | 1994 |
Diabetic rat aorta responsiveness to D600 and nifedipine.
Topics: Animals; Aorta; Diabetes Mellitus, Experimental; Gallopamil; In Vitro Techniques; Male; Nifedipine; | 1993 |
Effects of calcium antagonists on K(+)-induced contraction in isolated aorta from diabetic and age-matched control rats.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; In V | 1993 |
The effects of calcium channel blockers, verapamil, nifedipine and diltiazem, on metabolic control in diabetic rats.
Topics: Animals; Blood Glucose; Blood Proteins; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Ex | 1995 |
Impaired mechanical response to calcium of diabetic rat hearts: reversal by nifedipine treatment.
Topics: Analysis of Variance; Animals; Blood Glucose; Blood Pressure; Body Weight; Calcium; Diabetes Mellitu | 1995 |
Enhanced contractile responses of arteries from streptozotocin diabetic rats to sodium fluoride.
Topics: Adenylyl Cyclases; Aluminum Chloride; Aluminum Compounds; Animals; Aorta; Arteries; Calcium; Calcium | 1996 |
Long-term nifedipine treatment reduces calcium overload in isolated reperfused hearts of diabetic rats.
Topics: Animals; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Male; Myocardial Reperf | 1995 |
Differential effects of chronic calcium channel blocker treatment on the inotropic response of diabetic rat myocardium to acute ethanol exposure.
Topics: Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Drug Antagonism; Ethanol; Male; | 1996 |
Influence of calcium channel blocker treatment on the mechanical properties of diabetic rat myocardium.
Topics: Analysis of Variance; Animals; Blood Glucose; Body Weight; Calcium Channel Blockers; Diabetes Mellit | 1996 |
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium | 1996 |
Diabetes-induced changes in the contractility of the aorta and pA2 of nifedipine in the rat.
Topics: Animals; Aorta; Calcium; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contract | 1996 |
Microvascular permeability with sulfonylureas in normal and diabetic hamsters.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capillary Permeability; Cricetinae; Dextrans; D | 1997 |
[Pharmacological studies on alterations in contractile reactivity in aortas isolated from experimental diabetic rats].
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 3-Pyridinecarboxylic acid, 1,4-d | 1997 |
Measurement of left ventricular maximal isovolumetric pressure in rats: effects of antihypertensive drugs and diabetes mellitus.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals | 1998 |
Effects of the antihypertensive drug nifedipine on albuminuria and renal histopathology in young spontaneously hypertensive rats with diabetes.
Topics: Albuminuria; Animals; Antihypertensive Agents; Creatinine; Diabetes Mellitus, Experimental; Diabetic | 1999 |
Increased contractile responses to endothelin-1 and U46619 via a protein kinase C-mediated nifedipine-sensitive pathway in diabetic rat aorta.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Aorta; Calcium Channel | 1999 |
Predominant contribution of the G protein-mediated mechanism to NaF-induced vascular contractions in diabetic rats: association with an increased level of G(qalpha) expression.
Topics: Aluminum Chloride; Aluminum Compounds; Animals; Aorta, Thoracic; Astringents; Blotting, Western; Che | 2000 |
Effect of streptozotocin-induced diabetes on the activity of calcium channels in rat dorsal horn neurons.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Diabetes Mellitus, Experimenta | 2000 |
In vivo visualization of characteristics of renal microcirculation in hypertensive and diabetic rats.
Topics: Animals; Arterioles; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Hemo | 2001 |
Attenuated agonist evoked vasoconstrictor responses in the perfused mesenteric vascular bed of streptozotocin diabetic rats.
Topics: Animals; Blood Glucose; Body Weight; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Endo | 2001 |
Diabetes-induced changes in calcium homeostasis and the effects of calcium channel blockers in rat and mice nociceptive neurons.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Ganglia, Spin | 2001 |
Calcium channel agonist/antagonist effects on cholinergic stimulation of the diabetic rat bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Nifedipine versus fosinopril in uninephrectomized diabetic rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Fosinopril; Hemo | 1992 |
The effect of the calcium antagonist nifedipine on peripheral nerve function in streptozotocin-diabetic rats.
Topics: Action Potentials; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Male; Motor Neur | 1992 |
The influence of streptozotocin-induced diabetes mellitus on the sensitivity of rat urinary bladder body and base strips to changes in extracellular calcium.
Topics: Animals; Calcium; Carbachol; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Male | 1992 |
Alpha-adrenoceptor-mediated increase in cytosolic free calcium in isolated cardiac myocytes.
Topics: Animals; Calcium; Cell Separation; Cytosol; Diabetes Mellitus, Experimental; In Vitro Techniques; Ma | 1991 |
The effect of streptozotocin-induced diabetes on cholinergic motor transmission in the rat urinary bladder.
Topics: Acetylcholine; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Electric Stimul | 1991 |
Neurogenic function of the diabetic rat bladder: alteration by calcium channel effectors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Effects of nifedipine on global myocardial ischemic injury in hearts from diabetic and age-matched control rats.
Topics: Animals; Blood Pressure; Calcium; Coronary Circulation; Coronary Disease; Diabetes Mellitus, Experim | 1991 |
Contractile responses and calcium mobilization in renal arteries of diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1991 |
Evidence against a role of arachidonic acid metabolites in autoregulatory responses of the isolated perfused kidney of the rat.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Arachidonic Acid; Arachidonic | 1991 |
Activation of cyclic AMP phosphodiesterase by phorbol and protein kinase C pathway: differences in normal and diabetic tissue.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adipose Tissue; Animals; Calcimycin; Diabetes Mellitus, Experim | 1990 |
Protein kinase C-mediated contractile responses of arteries from diabetic rats.
Topics: Alkaloids; Animals; Aorta, Thoracic; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; In Vit | 1990 |
Effects of calcium channel blockers and hydralazine on plasma glucose levels in streptozotocin-induced diabetic rats in vivo.
Topics: Animals; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Catecholamines; Diabetes Mellitus, | 1990 |
Effect of chronic experimental diabetes on vascular smooth muscle function in rabbit carotid artery.
Topics: Alloxan; Animals; Carotid Arteries; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dru | 1987 |
Vascular responses to agonists in rat mesenteric artery from diabetic rats.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1987 |
Effect of calcium antagonists on hypertension and diabetes in new hypertensive diabetic models.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diltiazem; Disea | 1987 |
Effect of diabetes on vascular smooth muscle function in normotensive and spontaneously hypertensive rat mesenteric artery.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dr | 1987 |