Page last updated: 2024-11-01

nifedipine and Allodynia

nifedipine has been researched along with Allodynia in 11 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"Opioids can induce analgesia and also hyperalgesia in humans and in animals."1.35Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats. ( Ahmadiani, A; Esmaeili-Mahani, S; Javan, M; Koibuchi, N; Maghsoudi, N; Motamedi, F; Shimokawa, N, 2008)
"Nifedipine has an inhibitory effect on morphine-induced corticosterone secretion."1.34Nifedipine suppresses morphine-induced thermal hyperalgesia: evidence for the role of corticosterone. ( Ahmadiani, A; Esmaeili-Mahani, S; Fereidoni, M; Javan, M; Maghsoudi, N; Motamedi, F, 2007)
"Single ECT had no significant effect on thermal hyperalgesia or mechanical allodynia."1.30The effect of electroconvulsive treatment on thermal hyperalgesia and mechanical allodynia in a rat model of peripheral neuropathy. ( Inoue, T; Shibata, M; Shimizu, T; Wakisaka, S; Yoshiya, I, 1998)
" Chronic administration of electroconvulsive shock (once daily for 8 days) produced hyperalgesia, augmented locomotor responses to low doses of apomorphine and upregulation of cortical (but not hippocampal) voltage-dependent Ca2+ channels (assessed from [3H]nitrendipine binding)."1.29Modification of effects of chronic electroconvulsive shock by voltage-dependent Ca2+ channel blockade with nifedipine. ( Antkiewicz-Michaluk, L; Michaluk, J; Vetulani, J, 1994)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (36.36)18.2507
2000's4 (36.36)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, E1
Chen, X2
Kim, M1
Gong, N1
Bhatia, S1
Luo, ZD1
Uchida, K1
Demirkhanyan, L1
Asuthkar, S1
Cohen, A1
Tominaga, M1
Zakharian, E1
Achem, SR1
Vriens, J1
Owsianik, G1
Hofmann, T1
Philipp, SE1
Stab, J1
Benoit, M1
Xue, F1
Janssens, A1
Kerselaers, S1
Oberwinkler, J1
Vennekens, R1
Gudermann, T1
Nilius, B1
Voets, T1
Esmaeili-Mahani, S2
Fereidoni, M1
Javan, M2
Maghsoudi, N2
Motamedi, F2
Ahmadiani, A2
Shimokawa, N1
Koibuchi, N1
Kania, BF1
Lewicki, S1
Antkiewicz-Michaluk, L1
Michaluk, J1
Vetulani, J1
Shibata, M1
Wakisaka, S1
Inoue, T1
Shimizu, T1
Yoshiya, I1
White, DM1
Cousins, MJ1
Sluka, KA1

Reviews

1 review available for nifedipine and Allodynia

ArticleYear
Treatment of non-cardiac chest pain.
    Disease-a-month : DM, 2008, Volume: 54, Issue:9

    Topics: Anti-Ulcer Agents; Botulinum Toxins, Type A; Calcium Channel Blockers; Chest Pain; Diltiazem; Enzyme

2008

Trials

1 trial available for nifedipine and Allodynia

ArticleYear
Influence of nifedypine on the hyperalgesic action of duodenal distention in sheep.
    Polish journal of veterinary sciences, 2007, Volume: 10, Issue:4

    Topics: Analgesia; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Duodenal Diseases; F

2007

Other Studies

9 other studies available for nifedipine and Allodynia

ArticleYear
Differential effects of voltage-gated calcium channel blockers on calcium channel alpha-2-delta-1 subunit protein-mediated nociception.
    European journal of pain (London, England), 2015, Volume: 19, Issue:5

    Topics: Animals; Behavior, Animal; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cal

2015
Stimulation-dependent gating of TRPM3 channel in planar lipid bilayers.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:3

    Topics: Cell Line; Clotrimazole; HEK293 Cells; Hot Temperature; Humans; Hyperalgesia; Insulin-Secreting Cell

2016
TRPM3 is a nociceptor channel involved in the detection of noxious heat.
    Neuron, 2011, May-12, Volume: 70, Issue:3

    Topics: Acrylamides; Animals; Behavior, Animal; Blood Glucose; Bridged Bicyclo Compounds, Heterocyclic; Calc

2011
Nifedipine suppresses morphine-induced thermal hyperalgesia: evidence for the role of corticosterone.
    European journal of pharmacology, 2007, Jul-12, Volume: 567, Issue:1-2

    Topics: Adrenalectomy; Analgesics, Opioid; Animals; Calcium Channel Blockers; Corticosterone; Dose-Response

2007
Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats.
    Journal of neuroscience research, 2008, Feb-01, Volume: 86, Issue:2

    Topics: Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Chan

2008
Modification of effects of chronic electroconvulsive shock by voltage-dependent Ca2+ channel blockade with nifedipine.
    European journal of pharmacology, 1994, Mar-11, Volume: 254, Issue:1-2

    Topics: Animals; Apomorphine; Behavior, Animal; Calcium Channel Blockers; Calcium Channels; Cerebral Cortex;

1994
The effect of electroconvulsive treatment on thermal hyperalgesia and mechanical allodynia in a rat model of peripheral neuropathy.
    Anesthesia and analgesia, 1998, Volume: 86, Issue:3

    Topics: Animals; Calcium Channels; Disease Models, Animal; Electroshock; Hot Temperature; Hyperalgesia; Male

1998
Effect of subcutaneous administration of calcium channel blockers on nerve injury-induced hyperalgesia.
    Brain research, 1998, Aug-10, Volume: 801, Issue:1-2

    Topics: Afferent Pathways; Aminoquinolines; Animals; Behavior, Animal; Calcium; Calcium Channel Blockers; Ca

1998
Blockade of N- and P/Q-type calcium channels reduces the secondary heat hyperalgesia induced by acute inflammation.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 287, Issue:1

    Topics: Animals; Arthritis; Calcium Channel Blockers; Calcium Channels; Hot Temperature; Hyperalgesia; Male;

1998