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nifedipine and Adenoma, beta-Cell

nifedipine has been researched along with Adenoma, beta-Cell in 16 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"The phytostilbene resveratrol (RV) improves the metabolic state in animal models by increasing the insulin responsiveness of tissues and there is evidence that RV affects insulin secretion from native beta-cells and insulinoma cells."7.74Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents. ( Bacová, Z; Geibel, J; Iglseder, E; Jakab, M; Lach, S; Langelüddecke, C; Paulmichl, M; Ritter, M; Schmidt, S; Strbák, V, 2008)
"The high-voltage-activated (HVA) Ba2+ currents of rat insulinoma RINm5F cells insensitive to dihydropyridines (DHP) and omega-conotoxin GVIA (omega-CTx-GVIA) have been studied for their sensitivity to omega-agatoxin-IVA (omega-Aga-IVA) and omega-CTx-MVIIC."7.69Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC. ( Carbone, E; Magnelli, V; Pollo, A; Sher, E, 1995)
"In hamster insulinoma (HIT) cells, maitotoxin (MTX) induces a time-dependent and concentration-dependent release of insulin that requires the presence of extracellular calcium."7.68Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. ( Daly, JW; Gusovsky, F; Soergel, DG; Yasumoto, T, 1990)
"The phytostilbene resveratrol (RV) improves the metabolic state in animal models by increasing the insulin responsiveness of tissues and there is evidence that RV affects insulin secretion from native beta-cells and insulinoma cells."3.74Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents. ( Bacová, Z; Geibel, J; Iglseder, E; Jakab, M; Lach, S; Langelüddecke, C; Paulmichl, M; Ritter, M; Schmidt, S; Strbák, V, 2008)
"The high-voltage-activated (HVA) Ba2+ currents of rat insulinoma RINm5F cells insensitive to dihydropyridines (DHP) and omega-conotoxin GVIA (omega-CTx-GVIA) have been studied for their sensitivity to omega-agatoxin-IVA (omega-Aga-IVA) and omega-CTx-MVIIC."3.69Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC. ( Carbone, E; Magnelli, V; Pollo, A; Sher, E, 1995)
"Effects of genistein on insulin release were studied using MIN6 cells, a glucose-sensitive insulinoma cell line."3.68Genistein augments cyclic adenosine 3'5'-monophosphate(cAMP) accumulation and insulin release in MIN6 cells. ( Ishii, C; Ito, Y; Kato, N; Kawazu, S; Ohno, T; Shimizu, M; Tomono, S, 1993)
"In hamster insulinoma (HIT) cells, maitotoxin (MTX) induces a time-dependent and concentration-dependent release of insulin that requires the presence of extracellular calcium."3.68Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown. ( Daly, JW; Gusovsky, F; Soergel, DG; Yasumoto, T, 1990)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.25)18.7374
1990's11 (68.75)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jakab, M2
Ketterl, N1
Fürst, J1
Beyreis, M1
Kittl, M1
Kiesslich, T1
Hauser-Kronberger, C1
Gaisberger, M1
Ritter, M2
Lach, S1
Bacová, Z1
Langelüddecke, C1
Strbák, V1
Schmidt, S1
Iglseder, E1
Paulmichl, M1
Geibel, J1
Müller, I1
Endo, T1
Thiel, G1
Cui, X1
Yang, G1
Pan, M1
Zhang, XN1
Yang, SN1
Ohno, T1
Kato, N1
Ishii, C1
Shimizu, M1
Ito, Y1
Tomono, S1
Kawazu, S1
Magnelli, V3
Pollo, A2
Sher, E2
Carbone, E4
Mogami, H1
Shibata, H1
Nobusawa, R1
Ohnota, H1
Satou, F1
Miyazaki, J1
Kojima, I1
Marchetti, C1
Amico, C1
Podestà, D1
Robello, M1
Avaltroni, A1
Grassi, C1
Parlatore, E1
Caraher, EM1
Newsholme, P1
Platano, D1
Aicardi, G1
Wang, L1
Bhattacharjee, A1
Fu, J1
Li, M1
Thorn, P1
Petersen, OH1
Soergel, DG1
Gusovsky, F1
Yasumoto, T1
Daly, JW1
Findlay, I1
Dunne, MJ1

Other Studies

16 other studies available for nifedipine and Adenoma, beta-Cell

ArticleYear
The H+/K+ ATPase Inhibitor SCH-28080 Inhibits Insulin Secretion and Induces Cell Death in INS-1E Rat Insulinoma Cells.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2017, Volume: 43, Issue:3

    Topics: Animals; Apoptosis; Calcium; Cell Line, Tumor; Cell Size; Cell Survival; Colon; Enzyme-Linked Immuno

2017
Resveratrol inhibits electrical activity and insulin release from insulinoma cells by block of voltage-gated Ca+ channels and swelling-dependent Cl- currents.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2008, Volume: 22, Issue:5-6

    Topics: Animals; Calcium Channels; Chloride Channels; Glucose; Insulin; Insulin Secretion; Insulinoma; Ion C

2008
Regulation of AP-1 activity in glucose-stimulated insulinoma cells.
    Journal of cellular biochemistry, 2010, Aug-15, Volume: 110, Issue:6

    Topics: Animals; Blotting, Western; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line,

2010
Akt signals upstream of L-type calcium channels to optimize insulin secretion.
    Pancreas, 2012, Volume: 41, Issue:1

    Topics: Animals; Calcimycin; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Ionophores

2012
Genistein augments cyclic adenosine 3'5'-monophosphate(cAMP) accumulation and insulin release in MIN6 cells.
    Endocrine research, 1993, Volume: 19, Issue:4

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Cell Line; Cyclic AMP; Cytosol; Dose-Response Relatio

1993
Block of non-L-, non-N-type Ca2+ channels in rat insulinoma RINm5F cells by omega-agatoxin IVA and omega-conotoxin MVIIC.
    Pflugers Archiv : European journal of physiology, 1995, Volume: 429, Issue:6

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electric Stimulation; Insulin

1995
Inhibition of ATP-sensitive K+ channel by a non-sulfonylurea compound KAD-1229 in a pancreatic beta-cell line, MIN 6 cell.
    European journal of pharmacology, 1994, Nov-15, Volume: 269, Issue:3

    Topics: Action Potentials; Adenosine Triphosphate; Binding, Competitive; Calcium; Cell Membrane; Cobalt; Dos

1994
Inactivation of voltage-dependent calcium current in an insulinoma cell line.
    European biophysics journal : EBJ, 1994, Volume: 23, Issue:1

    Topics: Animals; Calcium Channel Blockers; Calcium Channels; Calcium Chloride; Cricetinae; Culture Media; El

1994
A single non-L-, non-N-type Ca2+ channel in rat insulin-secreting RINm5F cells.
    Pflugers Archiv : European journal of physiology, 1996, Volume: 431, Issue:3

    Topics: Animals; Barium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Drug Resistance; Insu

1996
Down-regulation of non-L-, non-N-type (Q-like) Ca2+ channels by Lambert-Eaton myasthenic syndrome (LEMS) antibodies in rat insulinoma RINm5F cells.
    FEBS letters, 1996, May-27, Volume: 387, Issue:1

    Topics: Animals; Autoantibodies; Calcium Channel Blockers; Calcium Channels; Down-Regulation; Humans; Immuno

1996
Investigation into the mechanisms of complement mediated cytotoxicity in pancreatic beta cells.
    Biochemical Society transactions, 1996, Volume: 24, Issue:1

    Topics: Animals; Apoptosis; Benzamides; Cell Death; Cell Line; Complement System Proteins; Culture Media; Gl

1996
Up-regulation of L- and non-L, non-N-type Ca2+ channels by basal and stimulated protein kinase C activation in insulin-secreting RINm5F cells.
    FEBS letters, 1996, Aug-05, Volume: 391, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Barium; Cadmium; Cadmium Chloride; Calcium Channel Blockers; Calciu

1996
Abnormally expressed low-voltage-activated calcium channels in beta-cells from NOD mice and a related clonal cell line.
    Diabetes, 1996, Volume: 45, Issue:12

    Topics: Amiloride; Animals; Calcium Channel Blockers; Calcium Channels; Cell Line; Clone Cells; Electric Con

1996
Activation of voltage-sensitive Ca2+ currents by vasopressin in an insulin-secreting cell line.
    The Journal of membrane biology, 1991, Volume: 124, Issue:1

    Topics: Animals; Barium; Biological Transport; Calcium; Calcium Channels; Dose-Response Relationship, Drug;

1991
Stimulatory effects of maitotoxin on insulin release in insulinoma HIT cells: role of calcium uptake and phosphoinositide breakdown.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Cinnarizine; Cricetinae;

1990
Voltage-activated Ca2+ and K+ currents in an insulin-secreting cell line (RINm5F).
    Advances in experimental medicine and biology, 1986, Volume: 211

    Topics: Animals; Calcium; Cell Line; Cell Membrane; Egtazic Acid; Insulin; Insulin Secretion; Insulinoma; Io

1986