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nifedipine and Acute Kidney Injury

nifedipine has been researched along with Acute Kidney Injury in 25 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
" Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury."7.85Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017)
"A patient with congestive heart failure and normal renal function developed anuria during treatment with nifedipine."7.67Acute renal failure during nifedipine therapy in a patient with congestive heart failure. ( Chalopin, JM; Eicher, JC; Louis, P; Morelon, P; Rifle, G; Tanter, Y, 1988)
" Antimicrobial therapy with voriconazole lowered the blood pressure, and then clarithromycin further lowered it through the excessively elevated nifedipine concentration, leading to ischemic acute kidney injury."3.85Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole. ( Abe, T; Ito, S; Maruyama, K; Mishima, E; Nakazawa, T, 2017)
"A patient with congestive heart failure and normal renal function developed anuria during treatment with nifedipine."3.67Acute renal failure during nifedipine therapy in a patient with congestive heart failure. ( Chalopin, JM; Eicher, JC; Louis, P; Morelon, P; Rifle, G; Tanter, Y, 1988)
"Postoperative acute renal failure predicts morbidity and mortality."2.73Renal function after cardiopulmonary bypass surgery in patients with impaired renal function. A randomized study of the effect of nifedipine. ( Bugge, JF; Geiran, OR; Hartmann, A; Witczak, BJ, 2008)
"We report a case of prolonged oliguric acute renal failure after renal transplantation under steroids and ciclosporin (Cs) immunosuppression."1.28Does calcium antagonist improve established early ciclosporin nephrotoxicity after renal transplantation? ( Andres, A; Montoyo, C; Morales, JM; Ortuño, B; Rodicio, JL, 1991)
"Diabetic nephropathy is the dominant cause of hypertension in insulin-dependent diabetics, and long-term rigid antihypertensive treatment inhibits the progression of nephropathy, probably even when there is renal insufficiency."1.28The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure. ( Conde, N; Gums, G; Heinke, P; Schulz, B; Strese, J; Zander, E; Zander, G, 1990)
"The possibility of a renal-related side effect from nifedipine has been investigated by comparing the effects on plasma creatinine level of coronary arteriography in two groups of patients: one group treated with nifedipine and the other treated with various drugs but without calcium inhibitor."1.27Renal side effect of nifedipine. ( Douste-Blazy, P; Pourrat, JP, 1984)
" The severity of CDDP-induced acute renal failure was markedly modified in N-treated animals according to the daily dosage of N."1.27Effects of nifedipine on cisplatinum-induced nephrotoxicity in rats. ( Anouar, M; Baumelou, A; Beaufils, H; Cacoub, P; Deray, G; Dubois, M; Jacobs, C; Jaudon, MC; Jouanneau, C, 1988)
"Verapamil was the only calcium-blocking drug which attenuated the post-ischaemic renal dysfunction."1.27Variable results of calcium blockade in post-ischaemic renal failure. ( Fitzpatrick, JM; Leahy, AL; Wait, RB, 1988)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199011 (44.00)18.7374
1990's7 (28.00)18.2507
2000's2 (8.00)29.6817
2010's3 (12.00)24.3611
2020's2 (8.00)2.80

Authors

AuthorsStudies
Rauser, MS1
McGrane, IR1
Uchendu, IK1
Agu, CE1
Nnedu, EB1
Chukwu, IJ1
Mishima, E1
Maruyama, K1
Nakazawa, T1
Abe, T1
Ito, S1
Shah, SP1
Self, TH1
Bradsher, RW1
Owens, RE1
Kusaba, J1
Kajikawa, N1
Kawasaki, H1
Kurosaki, Y1
Aiba, T1
Baeza, MT1
Merino, E1
Boix, V1
Climent, E1
Witczak, BJ1
Hartmann, A1
Geiran, OR1
Bugge, JF1
Scriabine, A1
Anderson, CL1
Janis, RA1
Kojima, K1
Rasmussen, H1
Lee, S1
Michal, U1
Burke, TJ1
Arnold, PE1
Gordon, JA1
Bulger, RE1
Dobyan, DC1
Schrier, RW1
Pourrat, JP1
Douste-Blazy, P1
Grewal, KS1
Schwartz, HR1
Krichbaum, D1
Dozen, M1
Watanabe, K1
Hosono, M1
Hayashi, Y1
Homsi, E1
Oliveira Dias, EP1
Garcia, WE1
Gontijo, JA1
Figueiredo, JF1
Dzgoeva, FU1
Kutyrina, IM1
Hermann, M1
Schulz, E1
Ruschitzka, F1
Müller, GA1
Morales, JM1
Andres, A1
Montoyo, C1
Ortuño, B1
Rodicio, JL1
Zander, E1
Conde, N1
Heinke, P1
Zander, G1
Strese, J1
Gums, G1
Schulz, B1
Lee, SM1
Michael, UF1
Eicher, JC1
Morelon, P1
Chalopin, JM1
Tanter, Y1
Louis, P1
Rifle, G1
Deray, G3
Dubois, M1
Beaufils, H1
Cacoub, P3
Anouar, M1
Jaudon, MC1
Baumelou, A2
Jouanneau, C1
Jacobs, C3
Blaser, KU1
Lämmle, B1
Cases, A1
Bosch, X1
Campistol, JM1
Botey, A1
Revert, L1
Leahy, AL1
Fitzpatrick, JM1
Wait, RB1
Deray, JY1
Grosgogeat, Y1

Trials

1 trial available for nifedipine and Acute Kidney Injury

ArticleYear
Renal function after cardiopulmonary bypass surgery in patients with impaired renal function. A randomized study of the effect of nifedipine.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:4

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Blood Pressure; Calcium Channel Blockers; Cardiopulmon

2008

Other Studies

24 other studies available for nifedipine and Acute Kidney Injury

ArticleYear
A CYP3A4 Drug-Drug Interaction Between Nirmatrelvir/Ritonavir and Nifedipine Leading to Edema, Oliguria, and Acute Kidney Injury: A Case Report.
    The Annals of pharmacotherapy, 2023, Volume: 57, Issue:8

    Topics: Acute Kidney Injury; Antiviral Agents; Cytochrome P-450 CYP3A; Edema; Humans; Nifedipine; Oliguria;

2023
Combination of aqueous extracts of Curcuma longa (turmeric) and some calcium channel blockers synergistically improves CCl4-induced nephrotoxicity in albino rats.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:5

    Topics: Acute Kidney Injury; Amlodipine; Animals; Antioxidants; Calcium Channel Blockers; Carbon Tetrachlori

2020
Acute Kidney Injury from Excessive Potentiation of Calcium-channel Blocker via Synergistic CYP3A4 Inhibition by Clarithromycin Plus Voriconazole.
    Internal medicine (Tokyo, Japan), 2017, Volume: 56, Issue:13

    Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Blood Pressure; Calcium Channel Blockers; Clarithr

2017
Clarithromycin-nifedipine-induced acute kidney injury.
    The Nurse practitioner, 2017, Sep-21, Volume: 42, Issue:9

    Topics: Acute Kidney Injury; Aged, 80 and over; Clarithromycin; Drug Interactions; Female; Humans; Hypotensi

2017
Comparative study on altered hepatic metabolism of CYP3A substrates in rats with glycerol-induced acute renal failure.
    Biopharmaceutics & drug disposition, 2012, Volume: 33, Issue:1

    Topics: Acute Kidney Injury; Animals; Cytochrome P-450 CYP3A; Glycerol; Male; Microsomes, Liver; Midazolam;

2012
Nifedipine-lopinavir/ritonavir severe interaction: a case report.
    AIDS (London, England), 2007, Jan-02, Volume: 21, Issue:1

    Topics: Acute Kidney Injury; Anti-HIV Agents; Drug Interactions; HIV Infections; Humans; Hypertension; Lopin

2007
Some recent pharmacological findings with nitrendipine.
    Journal of cardiovascular pharmacology, 1984, Volume: 6 Suppl 7

    Topics: Acute Kidney Injury; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel

1984
Protective effect of intrarenal calcium membrane blockers before or after renal ischemia. Functional, morphological, and mitochondrial studies.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:5

    Topics: Acute Kidney Injury; Animals; Calcium; Calcium Channel Blockers; Cytoplasm; Disease Models, Animal;

1984
Renal side effect of nifedipine.
    Clinical cardiology, 1984, Volume: 7, Issue:1

    Topics: Acute Kidney Injury; Contrast Media; Coronary Angiography; Creatinine; Humans; Male; Middle Aged; Ni

1984
Nifedipine and acute renal failure.
    Journal of general internal medicine, 1993, Volume: 8, Issue:12

    Topics: Acute Kidney Injury; Aged; Humans; Hypertension; Lung Diseases, Obstructive; Male; Nifedipine

1993
[Effect of cilnidipine on renal function in SHR and endothelin-induced renal dysfunction].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1996, Volume: 107, Issue:2

    Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Dihydropyridines; Diuresis; Endothelins; Hyp

1996
Effects of nifedipine and platelet activating factor antagonist (BN 52021) in glycerol-induced acute renal failure in rats.
    Renal failure, 1996, Volume: 18, Issue:6

    Topics: Acute Kidney Injury; Administration, Oral; Analysis of Variance; Animals; Creatinine; Disease Models

1996
[Endothelin-1 in the mechanisms of the nephrotoxic action of x-ray contrast media].
    Terapevticheskii arkhiv, 1997, Volume: 69, Issue:8

    Topics: Acute Kidney Injury; Adolescent; Adult; Calcium; Calcium Channel Blockers; Contrast Media; Creatinin

1997
Preventive strategies in endothelin-induced renal failure.
    Kidney international. Supplement, 1998, Volume: 67

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, No

1998
Does calcium antagonist improve established early ciclosporin nephrotoxicity after renal transplantation?
    Nephron, 1991, Volume: 57, Issue:2

    Topics: Acute Kidney Injury; Cyclosporins; Humans; Kidney Transplantation; Male; Middle Aged; Nifedipine

1991
The effect of antihypertensive treatment on kidney function in insulin-dependent (type I) diabetics with renal failure.
    Experimental and clinical endocrinology, 1990, Volume: 95, Issue:1

    Topics: Acute Kidney Injury; Antihypertensive Agents; Blood Pressure; Creatinine; Diabetes Mellitus, Type 1;

1990
The protective effect of nitrendipine on gentamicin acute renal failure in rats.
    Experimental and molecular pathology, 1985, Volume: 43, Issue:1

    Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Hemodynamics; Kidney; Kidney Diseases; Kidney Fun

1985
Acute renal failure during nifedipine therapy in a patient with congestive heart failure.
    Critical care medicine, 1988, Volume: 16, Issue:11

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Heart Failure; Humans; Male; Nifedipine; Renal Dialysi

1988
Effects of nifedipine on cisplatinum-induced nephrotoxicity in rats.
    Clinical nephrology, 1988, Volume: 30, Issue:3

    Topics: Acute Kidney Injury; Animals; Cisplatin; Dose-Response Relationship, Drug; Kidney; Kidney Tubular Ne

1988
[Acute hyperkalemia and non-oliguric kidney failure during treatment with indomethacin, allopurinol, nifedipine, hydrochlorothiazide/amiloride, trimethoprim/sulfamethoxazole and acetylsalicylic acid].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1988, Jan-19, Volume: 77, Issue:3

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Allopurinol; Amiloride; Aspirin; Drug Combinations; Dr

1988
Captopril vs. nifedipine.
    Clinical nephrology, 1987, Volume: 27, Issue:5

    Topics: Acute Kidney Injury; Captopril; Female; Humans; Middle Aged; Nifedipine; Scleroderma, Systemic

1987
No evidence for protective effects of nifedipine against radiocontrast-induced acute renal failure.
    Clinical nephrology, 1988, Volume: 29, Issue:4

    Topics: Acute Kidney Injury; Contrast Media; Humans; Kidney Failure, Chronic; Nifedipine; Retrospective Stud

1988
Variable results of calcium blockade in post-ischaemic renal failure.
    European urology, 1988, Volume: 14, Issue:3

    Topics: Acute Kidney Injury; Animals; Calcium Channel Blockers; Flunarizine; Ischemia; Kidney; Male; Nifedip

1988
Nifedipine-induced acute renal failure.
    Clinical nephrology, 1988, Volume: 29, Issue:5

    Topics: Acute Kidney Injury; Aged; Blood Pressure; Humans; Kidney Failure, Chronic; Male; Nifedipine

1988