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nifedipine and Abdominal Aortic Aneurysm

nifedipine has been researched along with Abdominal Aortic Aneurysm in 5 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
" The hemodynamic responses to captopril 25 mg SL (n = 10) and to nifedipine 10 mg SL (n = 10) were studied for 2 hours in patients (mean age 66 years) with arterial hypertension (mean blood pressure, Pa > or = 115 mmHg) the day after abdominal aortic surgery."9.07[Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually]. ( Degaute, JP; Leeman, M, 1993)
" Using this unique model we investigated effects on AAA formation of the L-type calcium channel blocker nifedipine, in view of the unclear relationship between hypertension and AAA, and unclear mechanisms of aneurysm protective effects of some blood pressure lowering drugs."7.81Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications. ( Cai, H; Miao, XN; Siu, KL, 2015)
"Aortic aneurysms are prevalent and severe vascular diseases with high mortality from unpredicted ruptures, while the only treatment option is surgical correction of large aneurysms with considerable risk."5.72Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication. ( Cai, H; Huang, K; Wu, Y; Youn, JY; Zhang, Y, 2022)
"Treatment with nifedipine resulted in a significant inhibition of the progression of AAA such as aneurismal dilation at 14 and 28 days compared to the control (week 2: control, 2."5.35Inhibition of experimental abdominal aortic aneurysm progression by nifedipine. ( Izawa, K; Kunugiza, Y; Morishita, R; Ogihara, T; Osako, MK; Tomita, N; Yamasaki, K, 2008)
" The hemodynamic responses to captopril 25 mg SL (n = 10) and to nifedipine 10 mg SL (n = 10) were studied for 2 hours in patients (mean age 66 years) with arterial hypertension (mean blood pressure, Pa > or = 115 mmHg) the day after abdominal aortic surgery."5.07[Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually]. ( Degaute, JP; Leeman, M, 1993)
" Using this unique model we investigated effects on AAA formation of the L-type calcium channel blocker nifedipine, in view of the unclear relationship between hypertension and AAA, and unclear mechanisms of aneurysm protective effects of some blood pressure lowering drugs."3.81Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications. ( Cai, H; Miao, XN; Siu, KL, 2015)
"Aortic aneurysms are prevalent and severe vascular diseases with high mortality from unpredicted ruptures, while the only treatment option is surgical correction of large aneurysms with considerable risk."1.72Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication. ( Cai, H; Huang, K; Wu, Y; Youn, JY; Zhang, Y, 2022)
"Treatment with nifedipine resulted in a significant inhibition of the progression of AAA such as aneurismal dilation at 14 and 28 days compared to the control (week 2: control, 2."1.35Inhibition of experimental abdominal aortic aneurysm progression by nifedipine. ( Izawa, K; Kunugiza, Y; Morishita, R; Ogihara, T; Osako, MK; Tomita, N; Yamasaki, K, 2008)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (40.00)18.2507
2000's1 (20.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Huang, K3
Wu, Y3
Zhang, Y3
Youn, JY3
Cai, H4
Miao, XN1
Siu, KL1
Tomita, N1
Yamasaki, K1
Izawa, K1
Kunugiza, Y1
Osako, MK1
Ogihara, T1
Morishita, R1
Leeman, M1
Degaute, JP1
Antonucci, F1
Calo, L1
Rizzolo, M1
Cantaro, S1
Bertolissi, M1
Travaglini, M1
Geatti, O1
Borsatti, A1
D'Angelo, A1

Trials

2 trials available for nifedipine and Abdominal Aortic Aneurysm

ArticleYear
[Treatment of arterial hypertension after surgery of the abdominal aorta: comparison of captopril and nifedipine administrated sublingually].
    Archives des maladies du coeur et des vaisseaux, 1993, Volume: 86, Issue:8

    Topics: Administration, Sublingual; Aged; Aortic Aneurysm, Abdominal; Captopril; Drug Evaluation; Humans; Hy

1993
Nifedipine can preserve renal function in patients undergoing aortic surgery with infrarenal crossclamping.
    Nephron, 1996, Volume: 74, Issue:4

    Topics: Aged; Aortic Aneurysm, Abdominal; Calcium Channel Blockers; Dopamine; Endothelins; Glomerular Filtra

1996

Other Studies

3 other studies available for nifedipine and Abdominal Aortic Aneurysm

ArticleYear
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
    Redox biology, 2022, Volume: 58

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic

2022
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
    Redox biology, 2022, Volume: 58

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic

2022
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
    Redox biology, 2022, Volume: 58

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic

2022
Combination of folic acid with nifedipine is completely effective in attenuating aortic aneurysm formation as a novel oral medication.
    Redox biology, 2022, Volume: 58

    Topics: Angiotensin II; Animals; Aortic Aneurysm; Aortic Aneurysm, Abdominal; Disease Models, Animal; Folic

2022
Nifedipine attenuation of abdominal aortic aneurysm in hypertensive and non-hypertensive mice: Mechanisms and implications.
    Journal of molecular and cellular cardiology, 2015, Volume: 87

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Aorta; Aortic Aneurysm, Abdominal; Calcium Channel

2015
Inhibition of experimental abdominal aortic aneurysm progression by nifedipine.
    International journal of molecular medicine, 2008, Volume: 21, Issue:2

    Topics: Animals; Aortic Aneurysm, Abdominal; Blood Pressure; Blotting, Western; Calcium Channel Blockers; Ce

2008