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nifedipine and ALS - Amyotrophic Lateral Sclerosis

nifedipine has been researched along with ALS - Amyotrophic Lateral Sclerosis in 7 studies

Nifedipine: A potent vasodilator agent with calcium antagonistic action. It is a useful anti-anginal agent that also lowers blood pressure.

Research Excerpts

ExcerptRelevanceReference
"To evaluate the role of excitotoxicity in the pathogenesis of amyotrophic lateral sclerosis (ALS), we compared the sensitivity of motor neurons and that of dorsal horn neurons to kainic acid (KA)."3.70Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons. ( Klaassen, H; Robberecht, W; Van Den Bosch, L; Van Houtte, E; Vandenberghe, W, 2000)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ikenaka, K1
Tsukada, Y1
Giles, AC1
Arai, T1
Nakadera, Y1
Nakano, S1
Kawai, K1
Mochizuki, H1
Katsuno, M1
Sobue, G1
Mori, I1
Pambo-Pambo, A1
Durand, J1
Gueritaud, JP1
Spalloni, A1
Pascucci, T1
Albo, F1
Ferrari, F1
Puglisi-Allegra, S1
Zona, C1
Bernardi, G1
Longone, P1
Sathasivam, S1
Grierson, AJ1
Shaw, PJ1
Magnelli, V1
Sawada, T1
Delbono, O2
Smith, RG1
Appel, SH2
Stefani, E2
Van Den Bosch, L1
Vandenberghe, W1
Klaassen, H1
Van Houtte, E1
Robberecht, W1
GarcĂ­a, J1

Other Studies

7 other studies available for nifedipine and ALS - Amyotrophic Lateral Sclerosis

ArticleYear
A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease.
    Scientific reports, 2019, 07-12, Volume: 9, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Dis

2019
Early excitability changes in lumbar motoneurons of transgenic SOD1G85R and SOD1G(93A-Low) mice.
    Journal of neurophysiology, 2009, Volume: 102, Issue:6

    Topics: Amyotrophic Lateral Sclerosis; Animals; Arginine; Biophysical Phenomena; Biophysics; Calcium Channel

2009
Altered vulnerability to kainate excitotoxicity of transgenic-Cu/Zn SOD1 neurones.
    Neuroreport, 2004, Nov-15, Volume: 15, Issue:16

    Topics: Amyotrophic Lateral Sclerosis; Analysis of Variance; Animals; Asparagine; Calcium Channel Blockers;

2004
Characterization of the caspase cascade in a cell culture model of SOD1-related familial amyotrophic lateral sclerosis: expression, activation and therapeutic effects of inhibition.
    Neuropathology and applied neurobiology, 2005, Volume: 31, Issue:5

    Topics: Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Calcium

2005
The action of amyotrophic lateral sclerosis immunoglobulins on mammalian single skeletal muscle Ca2+ channels.
    The Journal of physiology, 1993, Volume: 461

    Topics: Amyotrophic Lateral Sclerosis; Calcium Channels; Dihydropyridines; Humans; Immunoglobulin G; In Vitr

1993
Ca(2+)-permeable AMPA receptors and selective vulnerability of motor neurons.
    Journal of the neurological sciences, 2000, Nov-01, Volume: 180, Issue:1-2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Amyotrophic Lateral Sclerosis; Animals; Benzodiazepines; Calci

2000
IgG from amyotrophic lateral sclerosis affects tubular calcium channels of skeletal muscle.
    The American journal of physiology, 1991, Volume: 260, Issue:6 Pt 1

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Calcium Channels; Female; Humans; Immunoglobulin G; Male

1991