nicotine imine has been researched along with Tobacco Use Disorder in 2 studies
nicotine imine: RN given refers to 11C-labeled (S)-isomer
Tobacco Use Disorder: Tobacco used to the detriment of a person's health or social functioning. Tobacco dependence is included.
| Excerpt | Relevance | Reference |
|---|---|---|
| " An alternate metabolic route entails hydrolysis of nicotine iminium to an open-chain ketoamine that, in turn, undergoes nitrosation to form a toxic nitrosamine." | 1.33 | Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer. ( Cooksy, A; Kovacic, P, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bloom, AJ | 1 |
| Wang, PF | 1 |
| Kharasch, ED | 1 |
| Kovacic, P | 1 |
| Cooksy, A | 1 |
2 other studies available for nicotine imine and Tobacco Use Disorder
| Article | Year |
|---|---|
Nicotine oxidation by genetic variants of CYP2B6 and in human brain microsomes.
Topics: Aged; Aged, 80 and over; Brain; Cytochrome P-450 CYP2B6; Female; Humans; Ketamine; Male; Methadone; | 2019 |
Iminium metabolite mechanism for nicotine toxicity and addiction: Oxidative stress and electron transfer.
Topics: Animals; Computer Simulation; Electron Transport; Humans; Models, Biological; Nicotine; Oxidative St | 2005 |