nicotine has been researched along with Cancer of Lung in 349 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (20.63) | 18.7374 |
1990's | 43 (12.32) | 18.2507 |
2000's | 90 (25.79) | 29.6817 |
2010's | 105 (30.09) | 24.3611 |
2020's | 39 (11.17) | 2.80 |
Authors | Studies |
---|---|
Carroll, DM; Differding, M; Donny, EC; Hatsukami, DK; Katz, SJ; Strasser, AA; Strayer, LG; White, C | 1 |
Hati, S; Hu, Q; Huo, Z; Lu, J; Xing, C | 1 |
Jia, Y; Jiao, Y; Kang, G; Liu, Z; Ma, X; Pan, P; Zhang, Q; Zhu, P | 1 |
Deshpande, R; Li, W; Ruiz, J; Sharma, S; Singh, R; Topaloglu, U; Tyagi, A; Watabe, K; Wu, K; Wu, SY; Zhao, D | 1 |
Gorbyk, PP; Kravchuk, DI; Kravchuk, RM; Nazarenko, VG; Shcherbatiuk, MM; Shuba, YM; Sotkis, GV | 1 |
Ali, A; Chongtham, J; Jain, D; Lalwani, S; Mohan, A; Pal, S; Pandey, N; Srivastava, T | 1 |
Belli, R; Cui, X; Felip, E; Ghebremariam, S; Giovannini, M; Grohé, C; Hida, T; Kim, DW; Kim, SW; Leighl, NB; O'Sullivan-Djentuh, L; Ponce Aix, S; Riely, G; Sequist, LV; Smit, EF; Tan, DSW; Toyozawa, R; Wolf, J; Yang, JCH; Zou, M | 1 |
Abrams, D; Anderson, ED; Cao, P; Davis, KM; Jayasekera, J; Jeon, J; Li, T; Lobo, T; Luta, G; Mandelblatt, J; Meza, R; Niaura, R; Smith, L; Stanton, CA; Taylor, KL; Williams, RM | 1 |
Cao, P; Jayasekera, J; Jeon, J; Levy, DT; Mandelblatt, JS; Meza, R; Smith, L; Taylor, KL; Williams, RM; Zhao, A | 1 |
Alsharairi, NA | 3 |
Apolone, G; Boeri, M; Boffi, R; Gallus, S; Ladisa, V; Ledda, RE; Marchianò, A; Milanese, G; Munarini, E; Pastorino, U; Rolli, L; Sabia, F; Sozzi, G; Suatoni, P; Trussardo, S; Valsecchi, C | 1 |
Finnicum, CT; Fujimoto, J; Hassane, M; Hoffman, KL; Kadara, H; Liu, Y; Lorenzi, PL; Moghaddam, SJ; Morris, R; Petersen, JL; Petrosino, J; Rahal, Z; Sinjab, A; Tan, L; Tang, EL; Treekitkarnmongkol, W; Viet, S | 1 |
Al Khashali, H; Alomari, D; Coleman, KL; Evans, HG; Guthrie, J; Haddad, B; Heyl, D; Ranzenberger, R; Ray, R; Wareham, J | 1 |
Cui, S; Jin, C; Lu, X; Wu, S; Xiao, M; Yang, J; Zhang, G; Zhang, H; Zhang, J | 1 |
Jee, SH; Jung, KJ; Kim, GH; Kim, JM | 1 |
Belinsky, SA; Do, K; Dye, WW; Grimes, MJ; Juri, DE; Picchi, MA; Tellez, CS; Willink, R; Wu, G | 1 |
Fan, H; Jia, Y; Jiao, Y; Kang, G; Li, J; Li, Q; Li, X; Ma, X; Pan, P; Sun, H; Wang, Y; Zhang, L | 1 |
Huang, EY; Huang, HK; Huang, TT; Huang, TW; Hung, HY; Lin, PC | 1 |
Ding, K; Jiang, X; Li, A; Ni, J; Zhang, C; Zhou, J | 1 |
Abdulah, R; Abelia, XA; Barliana, MI; Goenawan, H; Lesmana, R | 1 |
Chang, X; Han, B; Liu, M; Qi, H; Wang, K; Xu, Q | 1 |
Bele, T; Križaj, I; Turk, T | 1 |
Balwierz, R; Bartoń, A; Delijewska, P; Delijewski, M; Jakubiak, G; Kośmider, L; Pawlas, N | 1 |
Chen, LC; Deng, FM; Huang, WC; Lee, HW; Lepor, H; Moreira, AL; Tang, MS; Wu, XR; Xia, Y | 1 |
Dziadziuszko, R; Jassem, J | 1 |
Aix, SP; Felip, E; Jonnaert, M; Kim, DW; Ko, J; Leighl, NB; Moody, SE; Pan, C; Riely, GJ; Sequist, LV; Seto, T; Tan, DS; Tan, EY; Wolf, J; Yang, JC | 1 |
Avraham, H; Chen, C; Ganapathy, S; Nishioka, T; Zhang, Q | 1 |
Scott, RJ; Young, RP | 1 |
Abbasnezhad, A; Abd El-Ghafar, OA; Abhilash, L; Abouzid, KAM; Achberger, AM; Ackerman, S; Akhatayeva, Z; Akin, D; Al-Kaysi, RO; Alakhdar, AA; Alame, M; Aleksic Sabo, V; Alinezhadbalalami, N; Allen, JD; Alonso, JM; Alqatani, S; Alsayed, B; Álvarez Larraondo, M; Alvarez, M; Amini, SB; An, Z; Anasir, MI; Anderson, GH; Andremont, A; Andrés, S; Angel, S; Anigboro, AA; Anini, Y; Antonides, CFJ; Arafa, K; Arafa, RK; Aryal, UK; Asbaghi, O; Assefa, MK; Atyah, M; Avwioroko, OJ; Ayora-Talavera, G; Azpilikueta, A; Azyazov, VN; Ba, YF; Bachmann, KF; Badoual, J; Bae, SJ; Baek, SH; Bahrami, B; Bai, J; Baid-Agrawal, S; Bailey, MR; Baillie, JK; Balani, N; Balcar, VJ; Banica, T; Banks, L; Barb, J; Bardeen, CJ; Barrett, HE; Bartnikowski, N; Bashir, R; Battaglia, M; Bautista-Hernández, V; Becker, B; Beekman, FJ; Benidir, M; Benjelloun, M; Bentley, RF; Bergé, J; Berger, D; Bernsen, MR; Berraondo, P; Bhattacharya, R; Bhayani, SB; Bi, W; Bi, X; Bi, YL; Bi, Z; Bian, K; Biesecker, LG; Billadeau, DD; Blaszczyk, R; Blum, JL; Boachie, R; Boelte, K; Bogers, AJJC; Boileau, I; Bonduelle, C; Bonny, O; Bonsu, JM; Boos, LA; Borges-Argáez, R; Bouchard, PA; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Boyle, AJ; Branigan, D; Briones, S; Broniowska, KA; Brossas, JY; Brown, WA; Brzezinska, J; Buitron, G; Burnier, M; Bursulaya, B; Burton, PR; Bush, AA; Busuttil, RW; Cabello-Aguilar, S; Cáceres-Farfán, M; Cacheux, V; Caffrey, PJ; Cai, B; Cai, Q; Cai, S; Cai, Y; Calders, P; Cammarota, G; Campbell, DA; Cancelli, C; Cao, Q; Cao, WH; Cao, X; Capet, M; Capoluongo, E; Carey, ME; Carnero, M; Carrasco, LI; Carreno, J; Carrillo-Reyes, J; Casini, I; Cassar, M; Catalan, G; Cattamanchi, A; Cazares-Granillo, M; Celie, B; Cen, YK; Cena, H; Cerbo, RM; Ceron, E; Cetina-Montejo, L; Chaâbane-Banaoues, R; Chabanet, C; Chace-Donahue, F; Chalfun-Júnior, A; Chan-Balan, R; Chang, CS; Chen, CS; Chen, D; Chen, J; Chen, L; Chen, PN; Chen, Q; Chen, S; Chen, W; Chen, WP; Chen, X; Chen, Z; Cheng, H; Cheng, J; Cheng, Q; Cheng, T; Chi, T; Chianelli, D; Chieppa, M; Child, CJ; Cho, JH; Cho, JY; Chogtu, B; Choi, GH; Choi, J; Choi, M; Choi, NG; Cholu, CO; Chow, ES; Chowdhury, AH; Chu, PC; Chu, Q; Chu, S; Chua, H; Chung, T; Chunyan, L; Church, JS; Civardi, E; Cobiella, J; Colinge, J; Collado, CJ; Collins, TJ; Cong, LM; Conkrite, KL; Cope, SJ; Corbett, JA; Cornet, M; Cornillot, E; Corvaisier, S; Costes-Martineau, V; Courtioux, B; Coussens, M; Covino, M; Criado, A; Cui, J; Cui, Y; Cunitz, BW; Curry, AE; Cussó, L; D'Urzo, AD; D'Urzo, KA; Dabbous, S; Dahlgren, RA; Dai, H; Dai, T; Dai, W; Dalinghaus, M; Dang, S; Davalos, RV; Davidson, H; de Andrea, CE; De Angelis, M; de Blois, E; de Carvalho, PA; De Clercq, E; De Giuseppe, R; de Jong, M; De Langhe, S; De Oliveira, L; de Souza Pinto Lemgruber, R; de Souza, LB; de Swart, J; De Wandele, I; de Woestijne, PCV; Delaney, S; Delorme, M; Delvenne, P; Deng, L; Deng, Z; Denkinger, CM; der Meulen, MHV; Deraeve, C; Desco, M; DeSilva, S; Destere, A; Dhali, A; Di Ciano, P; Dias-Santagata, D; Diskin, SJ; Djè, MK; Doddipatla, S; Doerr, AJ; Dokla, EME; Domiciano, D; Domingo, N; Dong, C; Dong, J; Dong, Q; Dong, S; Dong, X; Dong, Z; Douair, I; Douglas, TA; Doyle, SM; Drain, PK; Du, K; Du, L; Du, Q; Du, S; Duan, C; Duan, H; Duan, J; Duan, S; Duan, W; Dueluzeau, R; Dukic, L; Dunmire, BL; Duvauchelle, T; Dymek, B; Dzwonek, K; Earnest, A; Eckardt, KU; El Ghadraoui, L; El Massoudi, S; Elloumi, F; Elnour, IE; Embarak, S; Ende, M; England, K; Enikeev, D; Enyedy, I; Epple, R; Erickson, GE; Eriksson, J; Erndt-Marino, J; Errachidi, F; Etxeberria, I; Evan, AP; Fairlamb, AH; Falahi, E; Fan, CC; Fan, H; Fan, M; Fan, MZ; Fan, S; Fan, Y; Fang, CS; Fang, J; Fang, X; Fang, Z; Farmany, A; Farooqi, A; Farouk, HO; Fazelipour, S; Feng, D; Feng, J; Feng, JX; Feng, YL; Ferraz, SL; Ferreira, CR; Figenshau, RS; Finn, AV; Fiseha, T; Fleischer, AS; Fogleman, AD; Fontaine, O; Ford, CR; Fouladvand, F; Four, M; Fousteri, G; Francis, JR; Fraser, JF; Frazier, RP; Fu, H; Fu, P; Fu, YJ; Fujishima, A; Fuster, V; Gabilan, JC; Gagliani, N; Gai, QY; Galán-Arriola, C; Gale, P; Galimova, GR; Galkin, A; Gallo, A; Gallo, AA; Gang, DD; Ganschow, S; Gao, C; Gao, F; Gao, GP; Gao, H; Gao, K; Gao, M; Gao, MY; Gao, P; Gao, R; Gao, S; Gao, WJ; Gao, Y; Garbacz, P; García Ruiz, L; Garcia, EM; Garofoli, F; Gasbarrini, A; Gattinoni, L; Gaudig, M; Gbureck, U; Ge, X; Genko, N; Gentile, GL; George, MW; Gerety, GF; Gestwicki, JE; Geusens, PP; Ghassemi, M; Giardina, JD; Giebultowicz, JM; Gifford, CA; Gijsen, FJH; Gilfillan, R; Gilson, E; Gingl, K; Giuliano, C; Glybochko, P; Goessler, W; Gofflot, S; Golab, J; Goldstein, A; Golebiowski, A; Gómez, L; Gómez-Carballo, J; Gonçalves, PEO; Gonzales, R; Gonzalez-Cotto, M; González-Fernández, D; Gonzalez-Lopez de Turiso, F; Goodman, JM; Govinda Raju, S; Grimm, J; Gross, AJ; Gruenheid, S; Gu, C; Gu, FF; Gu, S; Gu, Z; Guest, RL; Gui, C; Gui, J; Guillem, A; Guo, G; Guo, L; Guo, Q; Guo, S; Guo, SW; Guo, W; Guo, Y; Guo, YG; Guo, Z; Guretzky, JA; Haenggi, M; Hahn, MS; Hakkola, J; Halim, AA; Hampel, D; Han, B; Han, BH; Han, D; Han, G; Han, J; Han, LZ; Han, R; Han, S; Han, X; Han, Z; Handley, MA; Hanke, I; Hannongbua, S; Hao, P; Happ, JT; Hara, M; Haraux, F; Hare, JL; Harper, JD; Hartley, AM; Harvey, E; Hashimoto, K; Hassan, HM; Hautajärvi, H; Hayton, TW; He, C; He, H; He, HJ; He, WP; He, Y; He, Z; Hedrick, V; Heffernan, JK; Hegrová, J; Heidarimoghadam, R; Helms, K; Hengphasatporn, K; Henry, D; Herrmann, TRW; Hesson, T; Himmelbauer, MK; Hindle, A; Hoffmann, R; Hogg, N; Hong, KB; Hong, SK; Honjol, Y; Hood, C; Hsi, RS; Hsu, JL; Hu, B; Hu, BC; Hu, D; Hu, H; Hu, J; Hu, K; Hu, M; Hu, MK; Hu, T; Hu, W; Hu, Y; Hu, Z; Hua, S; Huang, H; Huang, J; Huang, L; Huang, M; Huang, P; Huang, X; Huang, Y; Huang, Z; Hukkanen, J; Hung, MC; Huo, X; Hyötyläinen, T; Ianiro, G; Ibanez, B; Imran, M; Ireland, S; Irwin, MS; Ishiguro, H; Jackowski, K; Jackson, C; Jacob, SI; Jahromy, MH; Jakob, SM; Jang, J; Javvaji, PK; Jefferson, KK; Jena, P; Ji, H; Jiang, F; Jiang, GH; Jiang, H; Jiang, J; Jiang, X; Jiang, Z; Jiao, J; Jiménez, A; Jin, X; Jincai, W; Jintao, X; Jo, K; Jofra, T; Johari, Y; Johnson, ACM; Jones, JH; Josephine Fauci, A; Juhl, AK; Jun, S; Kaiser, RI; Kajioka, J; Kajiyama, H; Kalliyil, A; Kalthur, SG; Kamalanathan, M; Kamaldinov, T; Kanaani, L; Kang, D; Kang, J; Kang, S; Känsäkoski, P; Kaplan, DL; Karwan, M; Kasibhatla, S; Kaur, A; Kawazoe, Y; Ke, C; Keyser, J; Khalique, A; Khan, IT; Kharshoum, RM; Kher, R; Kherani, J; Ki, KK; Kikkawa, F; Kikkawa, R; Kim, BT; Kim, EH; Kim, GA; Kim, GD; Kim, HB; Kim, HG; Kim, JS; Kim, MJ; Kim, SI; Kim, SJ; Kim, Y; King, K; Kinyamu-Akunda, J; Kirkkala, T; Kjaer-Sorensen, K; Kleppinger, EL; Kloner, RA; Klopfenstein, TJ; Knappe, D; Knezevic, P; Kobos, LM; Kohli, M; Kolano, L; Kolodgie, FD; Kolte, AP; Koneru, B; Kong, D; Kong, F; Kong, X; Konggidinata, MI; Köpke, M; Koski, KG; Kotsis, F; Köttgen, A; Kouakou-Kouamé, CA; Kraemer, US; Krane, V; Krehbiel, CR; Krenning, BJ; Kretzschmar, D; Ku, KB; Kubota, Y; Kulich, P; Kumar, NG; Kupiec-Weglinski, JW; Lalani, SS; Lan, X; Landfeldt, E; Langenberg, E; Lapauw, B; Larkin, J; Lassoued, MA; Laukhtina, E; Laura Martinez, J; Laveillé, A; Lavela, P; Law, AD; Lazraq, A; Le Foll, B; Lee, BK; Lee, C; Lee, CS; Lee, EJ; Lee, EY; Lee, G; Lee, HY; Lee, JH; Lee, JJ; Lee, JO; Lee, JS; Lee, R; Lei, H; Lei, P; Lellouche, F; Lennerz, JK; Leong, W; Leslie, I; Lessem, E; Levin, M; Levinger, I; Li, C; Li, CW; Li, CX; Li, CY; Li, D; Li, H; Li, HM; Li, J; Li, L; Li, LM; Li, N; Li, S; Li, W; Li, X; Li, XX; Li, Y; Li, Z; Li, ZL; Li, ZX; Lian, Q; Liang, C; Liang, GH; Liang, H; Liang, J; Liang, X; Liao, CX; Liao, R; Ličbinský, R; Lim, YS; Lima, HK; Lin, JG; Lin, L; Lin, S; Lin, WP; Lin, Z; Liso, M; Liu, BX; Liu, C; Liu, H; Liu, J; Liu, M; Liu, Q; Liu, S; Liu, SF; Liu, SL; Liu, T; Liu, W; Liu, X; Liu, XB; Liu, Y; Liu, YY; Liu, Z; Liu, ZQ; Lobo, M; Loitzenbauer, M; López, F; Lopez, G; López, GJ; Lou, Z; Lu, IC; Lu, J; Lu, M; Lu, W; Lu, X; Lu, Y; Luhovyy, BL; Luna-Abanto, J; Luo, J; Luo, K; Luo, L; Luo, M; Luo, W; Luo, X; Luo, XM; Lv, Y; Lv, YQ; Lyu, HD; Lyu, J; Ma, C; Ma, G; Ma, L; Ma, Q; Ma, X; Ma, Y; Macha, SJ; MacLean, E; Mahalapbutr, P; Maina, T; Malfait, F; Malfertheiner, MV; Malzert-Fréon, A; Mansouri, E; Mao, C; Marcellin, E; Marchiori, PER; Marcotte, DJ; Maréchal, A; Maric, N; Maris, JM; Maron, L; Marti, CN; Martínez-Milla, J; Mateo, J; Mather, K; Mathison, CJN; Matthay, MA; Maxwell, CL; Mazier, D; Mazumder, D; Mazurkiewicz, M; Mazzucchelli, TG; McAuley, DF; Mccoy, K; McVicar, DW; Mebel, AM; Mech, A; Meester, EJ; Meiselbach, H; Melero, I; Ménard, G; Meng, X; Mengya, Y; Merle, G; Meunier, B; Mfarrej, B; Mi, K; Migueliz, I; Mikuška, P; Miladi, K; Miletich, R; Millar, JE; Mills, MR; Milne, R; Minute, L; Misiak, M; Mo, F; Modi, A; Mok, F; Molina, C; Mollen, CJ; Molteni, V; Montalto, M; Montet, D; Monti, MC; Moor, MB; Moravec, P; Morsiani, C; Murillo, E; Murugan, P; Muslem, R; Myers, RK; N'guessan, FK; Nabil, H; Nadal, J; Nadeem, M; Nafady, MM; Nafie, MS; Nair, HP; Nakano, R; Nance, J; Naren, N; Neil, CJ; Nelson, J; Nery, FC; Netsch, C; Nguyen, TH; Ni, L; Ni, YX; Nie, W; Nielsen, LK; Nigam, K; Nikolayev, AA; Nishiyama, M; Niu, LL; Niu, PP; Nock, BA; Noer, PR; Noll, G; Noll, S; Norenberg, JP; Nowicka, J; Nutho, B; O'Connor, M; Obonyo, NG; Ochiai, T; Ochoa, MC; Oh, BL; Oh, S; Olczak, J; Olivares, X; Ommurugan, B; Oosthuizen, MC; Operario, D; Orešič, M; Oshima, K; Otano, I; Ou, Y; Owen, TW; Oxvig, C; Pacey, V; Pai, M; Paik, H; Paiva, R; Palmieri, EM; Palpant, N; Pan, L; Pan, Q; Panahi, S; Pang, B; Pang, ZC; Pannecouque, C; Paris, L; Park, D; Park, DJ; Park, E; Park, EC; Park, IH; Park, JH; Park, JI; Park, S; Passmore, MR; Pattaranggoon, NC; Paun, M; Pedersen, S; Pedron, J; Peng, M; Peng, X; Penzhorn, BL; Pérez-Camargo, D; Perez-Maldonado, R; Pérez-Vicente, C; Pham, TD; Pickering, L; Pickersgill, NA; Pinault, E; Pinotsis, N; Plan, M; Pocino, K; Poh, CL; Pons, EDC; Popoff, MR; Porri, D; Pourmand, A; Pratviel, G; Prudente, DO; Qi, H; Qi, N; Qian, LY; Qiao, L; Qiao, Q; Qin, QP; Qiu, N; Qiu, SW; Qu, F; Quan, M; Quigg, A; Raee, E; Raibaud, P; Ramanitrahasimbola, D; Rapoport, L; Rasby, RJ; Rasoanirina, BNV; Raspini, B; Ratner, JR; Razafindrakoto, Z; Redd, MA; Ren, H; Ren, N; Rey, J; Reynolds, CP; Rich, PR; Richards, CJ; Rigol, M; Rimoldi, S; Robert, P; Rodrigues, AE; Roe, JH; Rohde, S; Rokita, JL; Roland, J; Rombaut, L; Ronkainen, J; Rothenberg, SM; Roy, SC; Ruan, Z; Rucker, PV; Rueda, D; Ruhwald, M; Rungrotmongkol, T; Rupert, AS; Rusjan, P; Ryabov, AD; Rysä, J; Saad, NES; Sabioni, P; Sadow, PM; Sahai, N; Salem, HF; Salinas, B; Salonurmi, T; Samé Guerra, D; Sánchez, J; Sanchez-González, J; Sanmamed, MF; Sansores-Peraza, P; Santoro, JC; Santschi, PH; Saritas, T; Sarkisova, Y; Savolainen, MJ; Scherberich, JE; Schlom, DG; Schmelz, EM; Schmid, MC; Schneider, MP; Schumacher, S; Schwartz, JC; Schwartzer, JJ; Schwehr, K; Schweitzer, DH; Scott, ME; Sedky, NK; See Hoe, L; Sejian, V; Selvaraju, S; Sen, SK; Seo, G; Šerý, O; Settles, JA; Sfar, S; Shaffer, J; Shan, GL; Shang, Q; Shannahan, JH; Shao, B; Shao, H; 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Han, S; Ritzenthaler, JD; Roman, J; Zheng, Y | 1 |
Catassi, A; Cavalieri, Z; Cesario, A; Grozio, A; Paleari, L; Russo, P | 1 |
Al-Wadei, HA; Majidi, M; Schuller, HM; Takahashi, T | 1 |
Le, AD; Shi, S; Tang, X; Velikina, R; Zhang, Q; Zhang, ZF | 1 |
Lerman, C; Patterson, F; Schnoll, RA | 1 |
Cooley, ME; Murphy, M; Sarna, L; Sipples, RL | 1 |
Faoro, L; Jagadeeswaran, R; Krishnaswamy, S; Loganathan, S; Salgia, R; Siddiqui, SS | 1 |
Schievelbein, H | 1 |
Ishikawa, S; Kuratomi, Y; Saito, T | 1 |
Ganguin, HG; Wilde, J | 1 |
Ashley, MJ; Keays, JJ; Lefcoe, NM; Pederson, LL | 1 |
Mennies, JH | 1 |
Ebert, RV; McCusker, KT; McNabb, ME; Snow, SL | 1 |
Lekić, M; Nikolin, B; Rashid Mahmud, MA; Vísnjevac, O | 1 |
Peters, G | 1 |
Morozov, VI; Zasedatelev, BB | 1 |
Bogden, JD; Buse, M; Forgacs, J; Kemp, FW; Llanos, G; Louria, DB; Moncoya Terrones, I; Thind, IS | 1 |
Lee, PN | 1 |
Zamorano, T | 1 |
Castonguay, A; Hecht, SS; Hoffmann, D; Rivenson, A | 1 |
Garfinkel, L; Lee, PN | 1 |
Chen, CB; Hecht, SS; Hoffmann, D; Ohmori, T | 1 |
Kretzschmar, RM | 1 |
Markiewicz, K | 1 |
McGavin, MD; Orloff, M; Porter, B; Riechert, A; Schuller, HM | 1 |
de Waard, F; Ellard, GA; Kemmeren, JM | 1 |
Klech, H | 1 |
Chan, J; Patrick, J; Quik, M | 1 |
Maneckjee, R; Minna, JD | 2 |
Cattaneo, MG; Clementi, F; Codignola, A; Sher, E; Vicentini, LM | 1 |
Lowrey, AH; Repace, JL | 1 |
Lagrue, G; Lebargy, F | 1 |
Brenna, E; Haugen, OA; Nilsen, OG; Nilsen, T; Rørvik, H; Sanvik, AK; Syversen, V; Torp, SH; Waldum, HL | 1 |
Hecht, SS; Hoffmann, D; Rivenson, A | 1 |
Froggatt, P; Waller, RE | 1 |
Nilsson, R | 1 |
Benowitz, NL; Gourlay, SG | 1 |
Cattaneo, MG; Clementi, F; Codignola, A; McIntosh, JM; Sher, E; Vicentini, LM | 1 |
Simpson, D | 1 |
Risser, NL | 1 |
Akerkar, SA; Borukhova, A; Carmella, SG; Hecht, SS | 1 |
Firat, D | 1 |
Cattaneo, MG; D'atri, F; Vicentini, LM | 1 |
Boccoli, E; Federici, A; Melani, AS; Trianni, GL | 1 |
Bayard, S; Emmons, K; Hammond, SK; Jinot, J; Repace, JL | 1 |
Codignola, A; Finardi, A; Missale, C; Paez-Pereda, M; Sher, E; Sigala, S; Spano, PF | 1 |
Heusch, WL; Maneckjee, R | 1 |
Hackshaw, AK | 1 |
Clementi, F; Codignola, A; Missale, C; Sher, E; Spano, P | 1 |
Carmella, SG; Chen, M; Dor Koch, JF; Hatsukami, DK; Hecht, SS; Jensen, JA; Miller, AT; Murphy, SE; Zimmerman, CL | 1 |
Coetzee, GA; Daly, AK; Idle, JR; London, SJ | 1 |
Idle, JR | 1 |
Szadkowska-Stańczyk, I; Szymczak, W | 1 |
Kunze, U; Schmeiser-Rieder, A; Schoberberger, R | 1 |
Brown, KG | 1 |
Bourdeau, HA; Davis, AL; Gubish, CT; Luketich, JD; Shriver, SP; Siegfried, JM; Tirpak, DL | 1 |
Burns, D; Henningfield, J; Pinney, J; Slade, J; Wilkenfeld, J | 1 |
Djordjevic, MV; Stellman, SD; Zang, E | 1 |
Plummer, HK; Schuller, HM; Sheppard, BJ; Williams, M | 1 |
Seidman, DS | 1 |
Prochazka, AV | 1 |
Boose, D; Escobedo-Morse, A; Kane, MA; Kautzman-Eades, D; Kelley, K; Meyer, M; Novak, J | 1 |
Anderson, KE; Bliss, RL; Carmella, SG; Hecht, SS; Le, C; Murphy, L; Ye, M | 1 |
Houghton, PJ; Jackson, S; Li, G; Twentyman, PR; Zhang, L | 1 |
Slama, K | 1 |
Dubois, G; Tramier, B | 1 |
Dautzenberg, B; Lagrue, G | 1 |
Adlkofer, F | 1 |
Cooke, JP; Heeschen, C; Hu, RS; Jang, JJ; Johnson, FL; Kaji, S; Pathak, A; Tsao, PS; Weis, M | 1 |
Damps, I; Jassem, E; Siemińska, A | 1 |
Gullstén, H; Pelkonen, O; Raunio, H; Rautio, A | 1 |
Burns, DM; Thun, MJ | 1 |
Benowitz, NL; Herrera, B; Jacob, P; Pérez-Stable, EJ | 1 |
Fasco, MJ; Hurteau, GJ; Spivack, SD | 1 |
Chen, GQ; Dawson, MI; Lin, B; Zhang, XK | 1 |
Hecht, SS; Hoffmann, D; Ornaf, RM; Tso, TC; Wynder, EL | 1 |
Betts, TE; Elson, LA | 2 |
Wald, NJ | 1 |
Chovil, AC | 1 |
Hammond, EC; Selikoff, IJ | 1 |
Sliwiński, S | 1 |
Chen, CB; Hecht, SS; Hirota, N; Hoffmann, D; Ornaf, RM; Tso, TC | 1 |
Gori, GB | 1 |
Garfinkel, L; Hammond, EC; Lew, EA; Seidman, H | 1 |
Barrett, LA; Connor, R; Frank, AL; Harris, CC; Jackson, F; Kaufman, DG; McDowell, EM; Trump, BF; van Haaften, C | 1 |
Dagle, GE; Veal, JT | 1 |
Kasuga, H | 1 |
Franklin, RA | 1 |
Cooke, TF | 1 |
Jarvis, MJ; Russell, MA | 1 |
Crawford, WA; Holcomb, LC | 1 |
Hof, S | 1 |
Brunnemann, KD; Mitacek, EJ; Polednak, AP | 1 |
Hirayama, T | 1 |
Byrd, JC; Joseph, AM | 1 |
Stellman, SD | 1 |
Vial, WC | 1 |
Engstrom, PF; Keintz, MK; Rimer, B; Strecher, V | 1 |
Tarentini Trojani, F | 1 |
Miller, GH | 1 |
Hecht, SS; Hoffmann, D; Lavoie, EJ | 1 |
Friedman, GD; Petitti, DB | 1 |
Berry, G; Newhouse, ML; Turok, M | 1 |
Mehrishi, JN | 1 |
Fenner, M | 1 |
Palombini, BC | 1 |
Mays, EE | 1 |
Betts, TE; Elson, LA; Passey, RD | 1 |
Boucot, KR; Carnahan, WJ; Seidman, H; Weiss, W | 1 |
Serebrov, AI | 1 |
Redman, DR | 1 |
Staszewski, J | 1 |
Schmähl, D | 1 |
Bock, FG | 1 |
Baumann, G; Dingman, JF; Lopez-Amor, E | 1 |
Cherry, WH; Forbes, WF | 1 |
Mabuchi, K; Wynder, EL | 1 |
Rusk, HS | 1 |
Schmidt, F | 1 |
Harke, HP | 1 |
Bendlová, J; Fingerland, A; Husák, T | 1 |
Godber, GE | 1 |
Beattie, EJ; Mabuchi, K; Wynder, EL | 1 |
Ochsner, A | 1 |
Peller, S | 1 |
70 review(s) available for nicotine and Cancer of Lung
Article | Year |
---|---|
Insights into the Mechanisms of Action of Proanthocyanidins and Anthocyanins in the Treatment of Nicotine-Induced Non-Small Cell Lung Cancer.
Topics: Anthocyanins; Carcinoma, Non-Small-Cell Lung; Flavonoids; Humans; Lung Neoplasms; Nicotine; Plants; Proanthocyanidins | 2022 |
Comparison impact of cigarettes and e-cigs as lung cancer risk inductor: a narrative review.
Topics: Electronic Nicotine Delivery Systems; Humans; Lung; Lung Neoplasms; Nicotiana; Nicotine; Tobacco Products | 2023 |
Nicotinic acetylcholine receptors in cancer: Limitations and prospects.
Topics: Cell Proliferation; Humans; Lung Neoplasms; Nicotine; Receptors, Nicotinic; Signal Transduction | 2024 |
Quercetin Derivatives as Potential Therapeutic Agents: An Updated Perspective on the Treatment of Nicotine-Induced Non-Small Cell Lung Cancer.
Topics: Anthocyanins; Carcinoma, Non-Small-Cell Lung; Flavonoids; Humans; Lung Neoplasms; Nicotine; Quercetin | 2023 |
Genetically determined metabolism of nicotine and its clinical significance.
Topics: Cigarette Smoking; Cytochrome P-450 CYP2A6; Heart Diseases; Humans; Lung Neoplasms; Nicotine; Polymorphism, Genetic | 2019 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Vaping and lung cancer - A review of current data and recommendations.
Topics: Electronic Nicotine Delivery Systems; Humans; Lung Neoplasms; Nicotine; Oncogenes; Vaping | 2021 |
Topics: Asthma; Carcinoma, Non-Small-Cell Lung; Flavanones; Flavones; Flavonoids; Humans; Lung Neoplasms; Nicotine; Plant Extracts; Plant Roots; Scutellaria baicalensis | 2021 |
The Influence of Nicotine on Lung Tumor Growth, Cancer Chemotherapy, and Chemotherapy-Induced Peripheral Neuropathy.
Topics: Animals; Antineoplastic Agents; Humans; Lung Neoplasms; Nicotine; Peripheral Nervous System Diseases | 2018 |
The impact of smoking and the influence of other factors on lung cancer.
Topics: Adenocarcinoma of Lung; Animals; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Nicotine; Pulmonary Disease, Chronic Obstructive; Receptors, Nicotinic; Risk Factors; Signal Transduction; Small Cell Lung Carcinoma; Smoking | 2019 |
Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers.
Topics: Apoptosis; Cell Cycle; Cell Proliferation; Disease Progression; DNA Damage; E2F1 Transcription Factor; Humans; Lung Neoplasms; MAP Kinase Signaling System; Neoplasm Metastasis; Nicotiana; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Retinoblastoma Protein; Smoking | 2014 |
Urinary tobacco smoke-constituent biomarkers for assessing risk of lung cancer.
Topics: Biomarkers; Carcinogens; Cotinine; Glucuronides; Humans; Lung Neoplasms; Mass Spectrometry; Multivariate Analysis; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Prospective Studies; Pyridines; Risk; Risk Assessment; Smoke | 2014 |
Connections of nicotine to cancer.
Topics: Animals; Humans; Lung Neoplasms; Nicotine; Signal Transduction | 2014 |
Effects of cigarette smoking on metabolism and effectiveness of systemic therapy for lung cancer.
Topics: Antineoplastic Agents; Camptothecin; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Deoxycytidine; Docetaxel; Enzyme Induction; Erlotinib Hydrochloride; Gemcitabine; Humans; Irinotecan; Lung Neoplasms; Neutropenia; Nicotine; Paclitaxel; Polycyclic Aromatic Hydrocarbons; Quinazolines; Smoking; Taxoids | 2014 |
Nicotine-induced resistance of non-small cell lung cancer to treatment--possible mechanisms.
Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Neoplasm Invasiveness; Neoplastic Processes; Neovascularization, Pathologic; Nicotine; Receptors, Nicotinic; Signal Transduction; Smoking | 2016 |
Modelling the health benefits of smoking cessation in Japan.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Female; Forecasting; Ganglionic Stimulants; Health Promotion; Humans; Japan; Lung Neoplasms; Male; Middle Aged; Models, Statistical; Nicotine; Nicotinic Antagonists; Prevalence; Risk Assessment; Smoking; Smoking Cessation; Smoking Prevention; Treatment Outcome | 2009 |
Nicotinic receptors and nicotine addiction.
Topics: Acetylcholine; Adolescent; Adult; Allosteric Regulation; Animals; Brain Chemistry; Genetic Predisposition to Disease; Humans; Ion Channels; Lung Neoplasms; Mice; Nicotine; Protein Subunits; Receptors, Nicotinic; Reward; Smoking; Synaptic Transmission; Tobacco Use Disorder; Torpedo; Ventral Tegmental Area | 2009 |
Destroyed documents: uncovering the science that Imperial Tobacco Canada sought to conceal.
Topics: Access to Information; Canada; Carcinogens; Conflict of Interest; Consumer Product Safety; Female; Humans; Lung Neoplasms; Male; Nicotine; Scientific Misconduct; Smoking; Tobacco Industry; Truth Disclosure; United Kingdom; United States | 2009 |
Why won't our patients stop smoking? The power of nicotine addiction.
Topics: Adolescent; Adult; Age Distribution; Aged; Cardiovascular Diseases; Humans; Lung Neoplasms; Middle Aged; Neoplasms; Nicotine; Smoking; Smoking Cessation; Substance-Related Disorders; Young Adult | 2009 |
From smoking to lung cancer: the CHRNA5/A3/B4 connection.
Topics: Animals; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Receptors, Nicotinic; Smoking; Substance-Related Disorders | 2010 |
[Why do not all smokers stop smoking?].
Topics: Health Knowledge, Attitudes, Practice; Humans; Lung Neoplasms; Nicotine; Physician-Patient Relations; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Switzerland; Tobacco Industry; Tobacco Use Disorder | 2010 |
Tobacco use and cessation among women: research and treatment-related issues.
Topics: Causality; Disease Susceptibility; Female; Humans; Life Style; Lung Neoplasms; Male; Nicotine; Prevalence; Pulmonary Disease, Chronic Obstructive; Risk Factors; Sex Distribution; Sex Factors; Smoking; Smoking Cessation | 2011 |
Nicotinic acetylcholine receptor-mediated mechanisms in lung cancer.
Topics: Animals; Autocrine Communication; Calcium; Cell Proliferation; Humans; Lung; Lung Neoplasms; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Signal Transduction | 2011 |
[Roles of nicotine and nicotinic acetylcholine receptors (nAChR) in carcinogenesis and development of lung cancer].
Topics: Animals; Carcinogens; Humans; Lung; Lung Neoplasms; Nicotine; Receptors, Nicotinic | 2011 |
Gamma-amino butyric acid inhibits the nicotine-imposed stimulatory challenge in xenograft models of non-small cell lung carcinoma.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Division; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Nicotine; Receptors, Nicotinic; Xenograft Model Antitumor Assays | 2012 |
Nicotinic receptor and tobacco-related cancer.
Topics: Animals; Humans; Lung Neoplasms; Neoplasms; Nicotiana; Nicotine; Polymorphism, Single Nucleotide; Receptors, Nicotinic | 2012 |
Lung carcinogenesis by tobacco smoke.
Topics: Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Adducts; Humans; Lung; Lung Neoplasms; Mutation; Nicotiana; Nicotine; Smoke | 2012 |
Association between CYP2A6 genetic polymorphisms and lung cancer: a meta-analysis of case-control studies.
Topics: Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cytochrome P-450 CYP2A6; Genotype; Humans; Lung Neoplasms; Nicotiana; Nicotine; Polymorphism, Genetic; Smoking | 2013 |
Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention.
Topics: Animals; Carcinogens; Chemoprevention; Disease Susceptibility; Female; Humans; Lung Neoplasms; Male; Models, Animal; Nicotiana; Nicotine; Primary Prevention; Prognosis; Research; Risk Assessment; Risk Factors; Rodentia; Sensitivity and Specificity; Smoking | 2002 |
Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer.
Topics: Animals; Apoptosis; Bronchi; Carcinogens; Enzyme Activation; Epithelial Cells; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic | 2003 |
[Clinical effects of smoking].
Topics: Adult; Age Factors; Aged; Animals; Bronchitis, Chronic; Cardiovascular Diseases; Coronary Disease; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Moscow; Nicotine; Rats; Respiratory Function Tests; Risk Factors; Sex Factors; Siberia; Smoking; Smoking Prevention; Time Factors; World Health Organization | 2002 |
Respiratory health effects of exposure to environmental tobacco smoke.
Topics: Asthma; Child; Environmental Exposure; Humans; Lung Neoplasms; Nicotine; Respiratory Function Tests; Respiratory Tract Diseases; Tobacco Smoke Pollution | 2003 |
Fifty years' experience of reduced-tar cigarettes: what do we know about their health effects?
Topics: Coronary Disease; Epidemiologic Studies; Humans; Lung Neoplasms; Nicotiana; Nicotine; Pulmonary Disease, Chronic Obstructive; Risk Assessment; Smoking; Tars; United States | 2003 |
Nicotine and angiogenesis: a new paradigm for tobacco-related diseases.
Topics: Animals; Arteriosclerosis; Carcinogens; Hexamethonium Compounds; Humans; Lung Neoplasms; Neovascularization, Pathologic; Nicotiana; Nicotine; Receptors, Nicotinic; Smoking | 2004 |
"Not lighting up": a case study of a woman who quit smoking.
Topics: Adolescent; Adult; Behavior, Addictive; Cause of Death; Child; Female; Humans; Incidence; Lung Neoplasms; Male; Mass Media; Middle Aged; Nicotine; Oncology Nursing; Patient Advocacy; Peer Group; Periodontal Diseases; Prevalence; Reinforcement, Social; Risk Assessment; Self Concept; Smoking; Smoking Cessation; Smoking Prevention; Survival Rate; United States; Women's Health | 2004 |
Reducing risk in smokers.
Topics: Bupropion; Chewing Gum; Counseling; Dopamine Uptake Inhibitors; Humans; Lung Neoplasms; Nicotine; Risk Reduction Behavior; Smoking; Smoking Cessation; Tobacco Use Disorder | 2004 |
Possible effects on smokers of cigarette mentholation: a review of the evidence relating to key research questions.
Topics: Adult; Black or African American; Blood Pressure; Carbon Monoxide; Cotinine; Female; Health Behavior; Heart Rate; Humans; Lung Neoplasms; Male; Menthol; Nicotine; Prevalence; Respiratory Mechanics; Risk Factors; Sex Factors; Smoking; Smoking Cessation; Tars | 2007 |
Nicotine-mediated cell proliferation and angiogenesis: new twists to an old story.
Topics: Cell Cycle; Cell Proliferation; Humans; Lung Neoplasms; Neovascularization, Pathologic; Nicotine; Receptors, Nicotinic | 2006 |
[Diagnosis and treatment of tobacco dependence].
Topics: Asthma; Comorbidity; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Poland; Prevalence; Public Health; Risk Factors; Sex Distribution; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Disorder | 2005 |
Nicotine, lung and cancer.
Topics: Animals; Bronchi; Cell Line, Tumor; Cell Proliferation; Cell Survival; Epithelial Cells; Humans; Lung; Lung Neoplasms; Models, Biological; Models, Chemical; Neoplasm Invasiveness; Neoplasm Metastasis; Nicotine; Receptors, Nicotinic | 2007 |
Treating tobacco dependence in women.
Topics: Benzazepines; Bupropion; Counseling; Dopamine Uptake Inhibitors; Female; Humans; Lung Neoplasms; Nicotine; Nicotinic Agonists; Quinoxalines; Risk Reduction Behavior; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Disorder; United States; Varenicline; Women's Health | 2007 |
Smoking cessation and lung cancer: oncology nurses can make a difference.
Topics: Benzazepines; Bupropion; Dopamine Uptake Inhibitors; Humans; Information Services; Lung Neoplasms; Nicotine; Oncology Nursing; Quinoxalines; Smoking; Smoking Cessation; Varenicline | 2008 |
[Smoking or health].
Topics: Adolescent; Adult; Aged; Arteriosclerosis; Bronchial Neoplasms; Carbon Monoxide; Cardiovascular Diseases; Female; Germany, East; Humans; Hydrogen Cyanide; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Peptic Ulcer; Plants, Toxic; Prognosis; Respiratory Tract Neoplasms; Smoke; Smoking | 1980 |
The health risks of passive smoking. The growing case for control measures in enclosed environments.
Topics: Adult; Carbon Monoxide; Cardiovascular Diseases; Child; Child, Preschool; Female; Humans; Legislation as Topic; Lung Diseases; Lung Neoplasms; Male; Nicotiana; Nicotine; Plants, Toxic; Pregnancy; Pulmonary Ventilation; Respiratory Hypersensitivity; Risk; Smoke; Tobacco Smoke Pollution; United States | 1983 |
[Do light cigarettes decrease the risk of smoking?].
Topics: Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Nicotine; Risk Factors; Smoking; Tars | 1994 |
[Smoking, one hundred years later].
Topics: Cardiovascular Diseases; Female; History, 20th Century; Humans; Lung Neoplasms; Male; Nicotine; Smoking; Social Behavior | 1993 |
The biological significance of tobacco-specific N-nitrosamines: smoking and adenocarcinoma of the lung.
Topics: Adenocarcinoma; Animals; Black People; Carcinogenicity Tests; Carcinogens; Cricetinae; Female; Humans; Lung Neoplasms; Male; Mice; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Smoking; Tars; United States; White People | 1996 |
Product modification.
Topics: Adult; Aged; Aged, 80 and over; Carbon Monoxide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Plants, Toxic; Smoking; Smoking Prevention; Tars | 1996 |
Environmental tobacco smoke and lung cancer: a reappraisal.
Topics: Diet; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Pollutants; Half-Life; Humans; Information Systems; Life Style; Lung Neoplasms; Nicotine; Quality Control; Risk Factors; Socioeconomic Factors; Tobacco Smoke Pollution; United States | 1996 |
The benefits of stopping smoking and the role of nicotine replacement therapy in older patients.
Topics: Administration, Cutaneous; Aged; Aging; Cardiovascular Diseases; Ganglionic Stimulants; Humans; Lung Neoplasms; Nicotine; Risk Factors; Smoking; Smoking Cessation | 1996 |
Prevention of lung cancer: the key is to stop smoking.
Topics: Behavior Therapy; Humans; Lung Neoplasms; Mass Screening; Nicotine; Nicotinic Agonists; Primary Prevention; Smoking; Smoking Cessation; Smoking Prevention | 1996 |
Tobacco and cancer: approaches using carcinogen biomarkers and chemoprevention.
Topics: Adult; Animals; Anticarcinogenic Agents; Biomarkers; Carcinogens; Chemoprevention; Humans; Isothiocyanates; Lung Neoplasms; Male; Neoplasms; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Risk Factors; Smoke; Smoking; Smoking Cessation; Smoking Prevention; Substance-Related Disorders | 1997 |
Lung cancer and passive smoking.
Topics: Biomarkers; Cotinine; Epidemiologic Factors; Epidemiologic Methods; Female; Humans; Lung Neoplasms; Male; Nicotiana; Nicotine; Plants, Toxic; Risk; Spouses; Tobacco Smoke Pollution | 1998 |
Prevention of lung cancer by long-term use of alternative nicotine delivery systems?
Topics: Female; Humans; Lung Neoplasms; Male; Nicotine; Nicotinic Agonists; Randomized Controlled Trials as Topic; Smoking Prevention; Time Factors | 1999 |
Lung cancer and environmental tobacco smoke: occupational risk to nonsmokers.
Topics: Adult; Female; Ganglionic Stimulants; Humans; Lung Neoplasms; Male; Nicotine; Occupational Exposure; Risk Assessment; Spouses; Tobacco Smoke Pollution | 1999 |
New developments in smoking cessation.
Topics: Administration, Cutaneous; Antidepressive Agents; Behavior Therapy; Bupropion; Counseling; Humans; Lung Neoplasms; Nicotine; Pamphlets; Smoking; Smoking Cessation; United States | 2000 |
The responsibility of the tobacco industry for the tobacco pandemic.
Topics: Adolescent; Adult; Child; Developing Countries; Ethics; Female; Health Knowledge, Attitudes, Practice; Humans; Incidence; Liability, Legal; Lung Neoplasms; Male; Nicotine; Risk Assessment; Smoking; Social Responsibility; Tobacco Industry; World Health Organization | 2001 |
Lung cancer due to passive smoking--a review.
Topics: Adult; Age Factors; Aged; Bias; Biomarkers; Case-Control Studies; Child; Confidence Intervals; Confounding Factors, Epidemiologic; Cotinine; Environmental Monitoring; Epidemiological Monitoring; Europe; Female; Germany; Humans; Interviews as Topic; Lung Neoplasms; Male; Meta-Analysis as Topic; Middle Aged; Multicenter Studies as Topic; Nicotine; Odds Ratio; Risk Factors; Smoke; Smoking; Time Factors; Tobacco Smoke Pollution; Workplace | 2001 |
Polymorphisms of CYP2A6 and its practical consequences.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cotinine; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Genetics, Population; Genotype; Humans; Lung Neoplasms; Mixed Function Oxygenases; Nicotine; Point Mutation; Polymorphism, Genetic; Smoking | 2001 |
Occupational lung cancer and smoking: a review in the light of current theories of carcinogenesis.
Topics: Arsenic; Asbestos; Bis(Chloromethyl) Ether; Carcinogens; Coal Tar; Drug Synergism; Humans; Lung Neoplasms; Neoplasms, Radiation-Induced; Nickel; Nicotine; Occupational Diseases; Risk; Smoking | 1979 |
Smoking.
Topics: Costs and Cost Analysis; Humans; Lung Neoplasms; Nicotine; Primary Prevention; Smoking; Smoking Cessation; Smoking Prevention; Substance-Related Disorders | 1992 |
Indoor air pollutants. A literature review.
Topics: Air Pollution, Indoor; Asbestos; Asphyxia; Carbon Monoxide; Cardiovascular Diseases; Formaldehyde; Humans; Hydrocarbons, Chlorinated; Lung Diseases; Lung Neoplasms; Nicotine; Pesticides; Radon; Smoke; Wood | 1991 |
Environmental tobacco smoke (ETS) in airliners--a health hazard evaluation.
Topics: Aerospace Medicine; Aircraft; Environmental Exposure; Humans; Lung Neoplasms; Nicotine; Tobacco Smoke Pollution; Ventilation | 1991 |
[Smoking and health].
Topics: Cardiovascular Diseases; Female; Humans; Lung Neoplasms; Male; Nicotine; Peptic Ulcer; Pregnancy; Smoking; Uterine Neoplasms | 1990 |
Smoking cessation in practice.
Topics: Chewing Gum; Female; Health Education; Humans; Lung Neoplasms; Male; Nicotine; Physician-Patient Relations; Referral and Consultation; Risk Factors; Smoking; Smoking Prevention; Socioeconomic Factors; United States | 1989 |
Cigarette yield and cancer risk: evidence from case-control and prospective studies.
Topics: Female; Filtration; Humans; Lung Neoplasms; Male; Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Prospective Studies; Retrospective Studies; Risk; Smoking; Tars | 1986 |
Cigarette smoking and lung disease.
Topics: Bronchitis; Chewing Gum; Female; Humans; Lung Diseases; Lung Diseases, Obstructive; Lung Neoplasms; Male; Nicotine; Prospective Studies; Smoking; Smoking Prevention; Tobacco Smoke Pollution; Tobacco Use Disorder; United States | 1986 |
Cigarette smoking: its relationship to other diseases.
Topics: Adult; Animals; Arteriosclerosis; Carbon Monoxide Poisoning; Cardiovascular Diseases; Cerebrovascular Disorders; Coronary Disease; Death, Sudden; Dogs; Female; Health Education; Hemodynamics; Humans; Lung Diseases; Lung Neoplasms; Male; Morbidity; Nicotine; Pregnancy; Pregnancy Complications; Rabbits; Smoking; Smoking Prevention | 1973 |
Smoking and health.
Topics: Adolescent; Adult; Animals; Cardiovascular Diseases; Coronary Disease; Humans; Lung Diseases; Lung Neoplasms; Middle Aged; Nicotine; Respiratory System; Smoking; United States | 1967 |
[Role of mortality statistics in epidemiological studies of neoplasms in Poland].
Topics: Age Factors; Death Certificates; Female; Humans; Lung Neoplasms; Male; Neoplasms; Nicotine; Poland; Sex Factors; Stomach Neoplasms; Time Factors | 1971 |
13 trial(s) available for nicotine and Cancer of Lung
Article | Year |
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Educating the Public on the Health Risks of Very Low Nicotine Content Cigarettes: Results From a US-Based Convenience Sample.
Topics: Adult; Behavior, Addictive; Humans; Lung Neoplasms; Nicotine; Smoking Cessation; Tobacco Products | 2022 |
Nazartinib for treatment-naive EGFR-mutant non-small cell lung cancer: Results of a phase 2, single-arm, open-label study.
Topics: Adult; Benzimidazoles; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Mutation; Nicotine; Protein Kinase Inhibitors | 2022 |
A Randomized Trial of Telephone-Based Smoking Cessation Treatment in the Lung Cancer Screening Setting.
Topics: Counseling; Early Detection of Cancer; Humans; Lung Neoplasms; Nicotine; Smoking Cessation; Telephone; Tobacco Use Cessation Devices | 2022 |
Cost-Effectiveness of a Telephone-Based Smoking Cessation Randomized Trial in the Lung Cancer Screening Setting.
Topics: Cost-Benefit Analysis; Early Detection of Cancer; Humans; Lung Neoplasms; Nicotine; Nicotinic Agonists; Smoking Cessation; Telephone; Tobacco Use Cessation Devices | 2022 |
Cytisine Therapy Improved Smoking Cessation in the Randomized Screening and Multiple Intervention on Lung Epidemics Lung Cancer Screening Trial.
Topics: Alkaloids; Azocines; Early Detection of Cancer; Humans; Lung; Lung Neoplasms; Nicotine; Quinolizines; Smoking Cessation; Varenicline | 2022 |
Safety and efficacy of nazartinib (EGF816) in adults with EGFR-mutant non-small-cell lung carcinoma: a multicentre, open-label, phase 1 study.
Topics: Aged; Antineoplastic Agents; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Treatment Outcome | 2020 |
Topics: A549 Cells; Acetylmuramyl-Alanyl-Isoglutamine; Acinetobacter baumannii; Acute Lung Injury; Adaptor Proteins, Signal Transducing; Adenine; Adenocarcinoma; Adipogenesis; Administration, Cutaneous; Administration, Ophthalmic; Adolescent; Adsorption; Adult; Aeromonas hydrophila; Aerosols; Aged; Aged, 80 and over; Aging; Agriculture; Air Pollutants; Air Pollution; Airway Remodeling; Alanine Transaminase; Albuminuria; Aldehyde Dehydrogenase 1 Family; Algorithms; AlkB Homolog 2, Alpha-Ketoglutarate-Dependent Dioxygenase; Alzheimer Disease; Amino Acid Sequence; Ammonia; Ammonium Compounds; Anaerobiosis; Anesthetics, Dissociative; Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Anti-HIV Agents; Anti-Infective Agents; Anti-Inflammatory Agents; Antibiotics, Antineoplastic; Antibodies, Antineutrophil Cytoplasmic; Antibodies, Monoclonal, Humanized; Antifungal Agents; Antigens, Bacterial; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antitubercular Agents; Antiviral Agents; Apolipoproteins E; Apoptosis; Arabidopsis; Arabidopsis Proteins; Arsenic; Arthritis, Rheumatoid; Asthma; Atherosclerosis; ATP-Dependent Proteases; Attitude of Health Personnel; Australia; Austria; Autophagy; Axitinib; Bacteria; Bacterial Outer Membrane Proteins; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Bariatric Surgery; Base Composition; Bayes Theorem; Benzoxazoles; Benzylamines; beta Catenin; Betacoronavirus; Betula; Binding Sites; Biological Availability; Biological Oxygen Demand Analysis; Biomarkers; Biomarkers, Tumor; Biopsy; Bioreactors; Biosensing Techniques; Birth Weight; Blindness; Blood Chemical Analysis; Blood Gas Analysis; Blood Glucose; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Blood-Brain Barrier; Blotting, Western; Body Mass Index; Body Weight; Bone and Bones; Bone Density; Bone Resorption; Borates; Brain; Brain Infarction; Brain Injuries, Traumatic; Brain Neoplasms; Breakfast; Breast Milk Expression; Breast Neoplasms; Bronchi; Bronchoalveolar Lavage Fluid; Buffaloes; Cadherins; Calcification, Physiologic; Calcium Compounds; Calcium, Dietary; Cannula; Caprolactam; Carbon; Carbon Dioxide; Carboplatin; Carcinogenesis; Carcinoma, Ductal; Carcinoma, Ehrlich Tumor; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Pancreatic Ductal; Carcinoma, Renal Cell; Cardiovascular Diseases; Carps; Carrageenan; Case-Control Studies; Catalysis; Catalytic Domain; Cattle; CD8-Positive T-Lymphocytes; Cell Adhesion; Cell Cycle Proteins; Cell Death; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Phone Use; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Cellulose; Chemical Phenomena; Chemoradiotherapy; Child; Child Development; Child, Preschool; China; Chitosan; Chlorocebus aethiops; Cholecalciferol; Chromatography, Liquid; Circadian Clocks; Circadian Rhythm; Circular Dichroism; Cisplatin; Citric Acid; Clinical Competence; Clinical Laboratory Techniques; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clostridioides difficile; Clostridium Infections; Coculture Techniques; Cohort Studies; Cold Temperature; Colitis; Collagen Type I; Collagen Type I, alpha 1 Chain; Collagen Type XI; Color; Connective Tissue Diseases; Copper; Coronary Angiography; Coronavirus 3C Proteases; Coronavirus Infections; Cost of Illness; Counselors; COVID-19; COVID-19 Testing; Creatine Kinase; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Cryoelectron Microscopy; Cryosurgery; Crystallography, X-Ray; Cues; Cultural Competency; Cultural Diversity; Curriculum; Cyclic AMP Response Element-Binding Protein; Cyclin-Dependent Kinase Inhibitor p21; Cycloparaffins; Cysteine Endopeptidases; Cytokines; Cytoplasm; Cytoprotection; Databases, Factual; Denitrification; Deoxycytidine; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diagnosis, Differential; Diatoms; Diet; Diet, High-Fat; Dietary Exposure; Diffusion Magnetic Resonance Imaging; Diketopiperazines; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Disease Progression; Disease-Free Survival; DNA; DNA Damage; DNA Glycosylases; DNA Repair; DNA-Binding Proteins; DNA, Bacterial; DNA, Viral; Docetaxel; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Down-Regulation; Doxorubicin; Drosophila; Drosophila melanogaster; Drug Carriers; Drug Delivery Systems; Drug Liberation; Drug Repositioning; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Drug Therapy, Combination; Edema; Edible Grain; Education, Graduate; Education, Medical, Graduate; Education, Pharmacy; Ehlers-Danlos Syndrome; Electron Transport Complex III; Electron Transport Complex IV; Electronic Nicotine Delivery Systems; Emergency Service, Hospital; Empathy; Emulsions; Endothelial Cells; Endurance Training; Energy Intake; Enterovirus A, Human; Environment; Environmental Monitoring; Enzyme Assays; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Epoxide Hydrolases; Epoxy Compounds; Erythrocyte Count; Erythrocytes; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Esophagectomy; Estrogens; Etanercept; Ethiopia; Ethnicity; Ethylenes; Exanthema; Exercise; Exercise Test; Exercise Tolerance; Extracellular Matrix; Extracorporeal Membrane Oxygenation; Eye Infections, Fungal; False Negative Reactions; Fatty Acids; Fecal Microbiota Transplantation; Feces; Female; Femur Neck; Fermentation; Ferritins; Fetal Development; Fibroblast Growth Factor-23; Fibroblast Growth Factors; Fibroblasts; Fibroins; Fish Proteins; Flavanones; Flavonoids; Focus Groups; Follow-Up Studies; Food Handling; Food Supply; Food, Formulated; Forced Expiratory Volume; Forests; Fractures, Bone; Fruit and Vegetable Juices; Fusobacteria; G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; Gamma Rays; Gastrectomy; Gastrointestinal Microbiome; Gastrointestinal Stromal Tumors; Gefitinib; Gels; Gemcitabine; Gene Amplification; Gene Expression; Gene Expression Regulation; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Neoplastic; Gene Expression Regulation, Plant; Gene Knockdown Techniques; Gene-Environment Interaction; Genotype; Germany; Glioma; Glomerular Filtration Rate; Glucagon; Glucocorticoids; Glycemic Control; Glycerol; Glycogen Synthase Kinase 3 beta; Glycolipids; Glycolysis; Goblet Cells; Gram-Negative Bacterial Infections; Granulocyte Colony-Stimulating Factor; Graphite; Greenhouse Effect; Guanidines; Haemophilus influenzae; HCT116 Cells; Health Knowledge, Attitudes, Practice; Health Personnel; Health Services Accessibility; Health Services Needs and Demand; Health Status Disparities; Healthy Volunteers; Heart Failure; Heart Rate; Heart Transplantation; Heart-Assist Devices; HEK293 Cells; Heme; Heme Oxygenase-1; Hemolysis; Hemorrhage; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis B, Chronic; Hepatocytes; Hexoses; High-Throughput Nucleotide Sequencing; Hippo Signaling Pathway; Histamine; Histamine Agonists; Histidine; Histone Deacetylase 2; HIV Infections; HIV Reverse Transcriptase; HIV-1; Homebound Persons; Homeodomain Proteins; Homosexuality, Male; Hospice and Palliative Care Nursing; HSP70 Heat-Shock Proteins; Humans; Hyaluronan Receptors; Hydrogen; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrolysis; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemia; Hypoglycemic Agents; Hypoxia; Idiopathic Interstitial Pneumonias; Imaging, Three-Dimensional; Imatinib Mesylate; Immunotherapy; Implementation Science; Incidence; INDEL Mutation; Induced Pluripotent Stem Cells; Industrial Waste; Infant; Infant, Newborn; Inflammation; Inflammation Mediators; Infliximab; Infusions, Intravenous; Inhibitory Concentration 50; Injections; Insecticides; Insulin-Like Growth Factor Binding Protein 5; Insulin-Secreting Cells; Interleukin-1; Interleukin-17; Interleukin-8; Internship and Residency; Intestines; Intracellular Signaling Peptides and Proteins; Ion Transport; Iridaceae; Iridoid Glucosides; Islets of Langerhans Transplantation; Isodon; Isoflurane; Isotopes; Italy; Joint Instability; Ketamine; Kidney; Kidney Failure, Chronic; Kidney Function Tests; Kidney Neoplasms; Kinetics; Klebsiella pneumoniae; Knee Joint; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lactate Dehydrogenase 5; Laparoscopy; Laser Therapy; Lasers, Semiconductor; Lasers, Solid-State; Laurates; Lead; Leukocyte L1 Antigen Complex; Leukocytes, Mononuclear; Light; Lipid Peroxidation; Lipopolysaccharides; Liposomes; Liver; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Locomotion; Longitudinal Studies; Lopinavir; Lower Urinary Tract Symptoms; Lubricants; Lung; Lung Diseases, Interstitial; Lung Neoplasms; Lymphocyte Activation; Lymphocytes, Tumor-Infiltrating; Lymphoma, Mantle-Cell; Lysosomes; Macrophages; Male; Manganese Compounds; MAP Kinase Kinase 4; Mass Screening; Maternal Health; Medicine, Chinese Traditional; Melanoma, Experimental; Memantine; Membrane Glycoproteins; Membrane Proteins; Mesenchymal Stem Cell Transplantation; Metal Nanoparticles; Metalloendopeptidases; Metalloporphyrins; Methadone; Methane; Methicillin-Resistant Staphylococcus aureus; Mexico; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Mice, Nude; Mice, SCID; Mice, Transgenic; Microarray Analysis; Microbial Sensitivity Tests; Microbiota; Micronutrients; MicroRNAs; Microscopy, Confocal; Microsomes, Liver; Middle Aged; Milk; Milk, Human; Minority Groups; Mitochondria; Mitochondrial Membranes; Mitochondrial Proteins; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Epidemiology; Molecular Structure; Molecular Weight; Multilocus Sequence Typing; Multimodal Imaging; Muscle Strength; Muscle, Skeletal; Muscular Diseases; Mutation; Mycobacterium tuberculosis; Myocardial Stunning; Myristates; NAD(P)H Dehydrogenase (Quinone); Nanocomposites; Nanogels; Nanoparticles; Nanotechnology; Naphthalenes; Nasal Cavity; National Health Programs; Necrosis; Needs Assessment; Neoadjuvant Therapy; Neonicotinoids; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Recurrence, Local; Neoplasm Staging; Neoplasm Transplantation; Neoplasms; Neoplastic Stem Cells; Netherlands; Neuroblastoma; Neuroprotective Agents; Neutrophils; NF-kappa B; NFATC Transcription Factors; Nicotiana; Nicotine; Nitrates; Nitrification; Nitrites; Nitro Compounds; Nitrogen; Nitrogen Dioxide; North Carolina; Nuclear Magnetic Resonance, Biomolecular; Nuclear Proteins; Nucleic Acid Hybridization; Nucleosomes; Nutrients; Obesity; Obesity, Morbid; Oceans and Seas; Oncogene Protein v-akt; Oncogenes; Oocytes; Open Reading Frames; Osteoclasts; Osteogenesis; Osteoporosis; Osteoporosis, Postmenopausal; Outpatients; Ovarian Neoplasms; Ovariectomy; Overweight; Oxazines; Oxidants; Oxidation-Reduction; Oxidative Stress; Oxides; Oxidoreductases; Oxygen; Oxygen Inhalation Therapy; Oxygenators, Membrane; Ozone; Paclitaxel; Paenibacillus; Pain Measurement; Palliative Care; Pancreatic Neoplasms; Pandemics; Parasympathetic Nervous System; Particulate Matter; Pasteurization; Patient Preference; Patient Satisfaction; Pediatric Obesity; Permeability; Peroxiredoxins; Peroxynitrous Acid; Pharmaceutical Services; Pharmacists; Pharmacy; Phaseolus; Phenotype; Phoeniceae; Phosphates; Phosphatidylinositol 3-Kinases; Phospholipid Transfer Proteins; Phospholipids; Phosphorus; Phosphorylation; Photoperiod; Photosynthesis; Phylogeny; Physical Endurance; Physicians; Pilot Projects; Piperidines; Pituitary Adenylate Cyclase-Activating Polypeptide; Plant Extracts; Plant Leaves; Plant Proteins; Plant Roots; Plaque, Atherosclerotic; Pneumonia; Pneumonia, Viral; Point-of-Care Testing; Polyethylene Glycols; Polymers; Polysorbates; Pore Forming Cytotoxic Proteins; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Postprandial Period; Poverty; Pre-Exposure Prophylaxis; Prediabetic State; Predictive Value of Tests; Pregnancy; Pregnancy Trimester, First; Pregnancy, High-Risk; Prenatal Exposure Delayed Effects; Pressure; Prevalence; Primary Graft Dysfunction; Primary Health Care; Professional Role; Professionalism; Prognosis; Progression-Free Survival; Prolactin; Promoter Regions, Genetic; Proof of Concept Study; Proportional Hazards Models; Propylene Glycol; Prospective Studies; Prostate; Protein Binding; Protein Biosynthesis; Protein Isoforms; Protein Kinase Inhibitors; Protein Phosphatase 2; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein Transport; Proteoglycans; Proteome; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-myc; Proto-Oncogene Proteins c-ret; Proto-Oncogene Proteins p21(ras); Proton Pumps; Protons; Protoporphyrins; Pseudomonas aeruginosa; Pseudomonas fluorescens; Pulmonary Artery; Pulmonary Disease, Chronic Obstructive; Pulmonary Gas Exchange; Pulmonary Veins; Pyrazoles; Pyridines; Pyrimidines; Qualitative Research; Quinoxalines; Rabbits; Random Allocation; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Histamine H3; Receptors, Immunologic; Receptors, Transferrin; Recombinant Proteins; Recurrence; Reference Values; Referral and Consultation; Regional Blood Flow; Registries; Regulon; Renal Insufficiency, Chronic; Reperfusion Injury; Repressor Proteins; Reproducibility of Results; Republic of Korea; Research Design; Resistance Training; Respiration, Artificial; Respiratory Distress Syndrome; Respiratory Insufficiency; Resuscitation; Retinal Dehydrogenase; Retreatment; Retrospective Studies; Reverse Transcriptase Inhibitors; Rhinitis, Allergic; Ribosomal Proteins; Ribosomes; Risk Assessment; Risk Factors; Ritonavir; Rivers; RNA Interference; RNA-Seq; RNA, Messenger; RNA, Ribosomal, 16S; RNA, Small Interfering; Rosuvastatin Calcium; Rural Population; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salivary Ducts; Salivary Gland Neoplasms; San Francisco; SARS-CoV-2; Satiation; Satiety Response; Schools; Schools, Pharmacy; Seasons; Seawater; Selection, Genetic; Sequence Analysis, DNA; Serine-Threonine Kinase 3; Sewage; Sheep; Sheep, Domestic; Shock, Hemorrhagic; Signal Transduction; Silver; Silymarin; Single Photon Emission Computed Tomography Computed Tomography; Sirolimus; Sirtuin 1; Skin; Skin Neoplasms; Skin Physiological Phenomena; Sleep Initiation and Maintenance Disorders; Social Class; Social Participation; Social Support; Soil; Soil Microbiology; Solutions; Somatomedins; Soot; Specimen Handling; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis; Spinal Fractures; Spirometry; Staphylococcus aureus; STAT1 Transcription Factor; STAT3 Transcription Factor; Streptomyces coelicolor; Stress, Psychological; Stroke; Stroke Volume; Structure-Activity Relationship; Students, Medical; Students, Pharmacy; Substance Abuse Treatment Centers; Sulfur Dioxide; Surface Properties; Surface-Active Agents; Surveys and Questionnaires; Survival Analysis; Survival Rate; Survivin; Sweden; Swine; Swine, Miniature; Sympathetic Nervous System; T-Lymphocytes, Regulatory; Talaromyces; Tandem Mass Spectrometry; tau Proteins; Telemedicine; Telomerase; Telomere; Telomere Homeostasis; Temperature; Terminally Ill; Th1 Cells; Thiamethoxam; Thiazoles; Thiophenes; Thioredoxin Reductase 1; Thrombosis; Thulium; Thyroid Cancer, Papillary; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Time Factors; Titanium; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Transcription Factor AP-1; Transcription Factors; Transcription, Genetic; Transcriptional Activation; Transcriptome; Transforming Growth Factor beta1; Transistors, Electronic; Translational Research, Biomedical; Transplantation Tolerance; Transplantation, Homologous; Transportation; Treatment Outcome; Tretinoin; Tuberculosis, Multidrug-Resistant; Tuberculosis, Pulmonary; Tubulin Modulators; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Twins; Ultrasonic Therapy; Ultrasonography; Ultraviolet Rays; United States; Up-Regulation; Uranium; Urethra; Urinary Bladder; Urodynamics; Uromodulin; Uveitis; Vasoconstrictor Agents; Ventricular Function, Left; Vero Cells; Vesicular Transport Proteins; Viral Nonstructural Proteins; Visual Acuity; Vital Capacity; Vitamin D; Vitamin D Deficiency; Vitamin K 2; Vitamins; Volatilization; Voriconazole; Waiting Lists; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Whole Genome Sequencing; Wine; Wnt Signaling Pathway; Wound Healing; Wounds and Injuries; WW Domains; X-linked Nuclear Protein; X-Ray Diffraction; Xanthines; Xenograft Model Antitumor Assays; YAP-Signaling Proteins; Yogurt; Young Adult; Zebrafish; Zebrafish Proteins; Ziziphus | 2016 |
Clinical efficacy and safety of nazartinib for epidermal growth factor receptor mutated non-small cell lung cancer: Study protocol for a prospective, multicenter, open-label.
Topics: Benzimidazoles; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Multicenter Studies as Topic; Mutation; Nicotine; Progression-Free Survival; Prospective Studies; Protein Kinase Inhibitors; Randomized Controlled Trials as Topic | 2021 |
E-cigarettes May Support Smokers With High Smoking-Related Risk Awareness to Stop Smoking in the Short Run: Preliminary Results by Randomized Controlled Trial.
Topics: Counseling; Double-Blind Method; Early Detection of Cancer; Electronic Nicotine Delivery Systems; Female; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Smokers; Smoking Cessation; Smoking Prevention; Tobacco Smoking | 2019 |
β-Carotene Supplementation and Lung Cancer Incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: The Role of Tar and Nicotine.
Topics: Aged; alpha-Tocopherol; Antioxidants; beta Carotene; Dietary Supplements; Double-Blind Method; Finland; Follow-Up Studies; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Nicotine; Provitamins; Smoking; Tars | 2019 |
Nicotine induces the up-regulation of the α7-nicotinic receptor (α7-nAChR) in human squamous cell lung cancer cells via the Sp1/GATA protein pathway.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Cell Line, Tumor; Female; GATA4 Transcription Factor; GATA6 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Neoplasm Proteins; Neoplasms, Squamous Cell; Nicotine; Nicotinic Agonists; Response Elements; Smoking; Sp1 Transcription Factor; Tobacco Smoke Pollution; Up-Regulation | 2013 |
Smoking cessation is followed by increases in serum bilirubin, an endogenous antioxidant associated with lower risk of lung cancer and cardiovascular disease.
Topics: Administration, Cutaneous; Adult; Antioxidants; Bilirubin; Cardiovascular Diseases; Counseling; Double-Blind Method; Female; Humans; Lung Neoplasms; Male; Middle Aged; Naltrexone; Nicotine; Risk Factors; Smoking; Smoking Cessation; Tobacco Use Cessation Devices; Treatment Outcome | 2014 |
Perceived Health Risks of Snus and Medicinal Nicotine Products.
Topics: Aged; Behavior, Addictive; Bronchitis; Emphysema; Female; Harm Reduction; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Patient Compliance; Patient Dropouts; Patient Satisfaction; Smoking; Smoking Cessation; Smoking Prevention; Tobacco Use Cessation Devices; Tobacco Use Disorder; Tobacco, Smokeless | 2016 |
267 other study(ies) available for nicotine and Cancer of Lung
Article | Year |
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In vivo Structure-Activity Relationship of Dihydromethysticin in Reducing Nicotine-Derived Nitrosamine Ketone (NNK)-Induced Lung DNA Damage against Lung Carcinogenesis in A/J Mice.
Topics: Animals; Carcinogenesis; Carcinogens; DNA Damage; Ketones; Lung; Lung Neoplasms; Mice; Nicotine; Nitrosamines; Pyrones; Structure-Activity Relationship | 2022 |
The role of α5-nicotinic acetylcholine receptor/NLRP3 signaling pathway in lung adenocarcinoma cell proliferation and migration.
Topics: Adenocarcinoma of Lung; Adenosine Triphosphate; Animals; Cell Line, Tumor; Cell Proliferation; Chick Embryo; Humans; Inflammasomes; Inflammation; Lipopolysaccharides; Lung Neoplasms; Mice; Nicotine; NLR Family, Pyrin Domain-Containing 3 Protein; Receptors, Nicotinic; Signal Transduction | 2022 |
Exosomal miR-4466 from nicotine-activated neutrophils promotes tumor cell stemness and metabolism in lung cancer metastasis.
Topics: Brain Neoplasms; Cell Line, Tumor; Exosomes; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Neoplasm Metastasis; Neutrophils; Nicotine; Retrospective Studies | 2022 |
Induction of A549 Nonsmall-Cell Lung Cancer Cells Proliferation by Photoreleased Nicotine.
Topics: A549 Cells; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Humans; Lung Neoplasms; Nicotine | 2023 |
When "No-Smoking" is not enough: Hypoxia and nicotine acetylcholine receptor signaling may drive lung adenocarcinoma progression in never-smokers.
Topics: Acetylcholine; Adenocarcinoma of Lung; alpha7 Nicotinic Acetylcholine Receptor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Lung Neoplasms; Nicotine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic; Signal Transduction; Smokers | 2023 |
Pathogenesis of Tobacco-Associated Lung Adenocarcinoma Is Closely Coupled with Changes in the Gut and Lung Microbiomes.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Butyrates; Carcinogens; Dysbiosis; Growth Inhibitors; Humans; Ketones; Lung; Lung Neoplasms; Mice; Microbiota; Nicotiana; Nicotine; Nitrosamines; Propionates; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S | 2022 |
Regulation of Cisplatin Resistance in Lung Cancer Cells by Nicotine, BDNF, and a β-Adrenergic Receptor Blocker.
Topics: Adrenergic Antagonists; Brain-Derived Neurotrophic Factor; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Nicotine; Phosphatidylinositol 3-Kinases; Propranolol; Proto-Oncogene Proteins c-akt; Receptors, Adrenergic, beta | 2022 |
Transcription factor SP1 and oncoprotein PPP1R13L regulate nicotine-induced epithelial-mesenchymal transition in lung adenocarcinoma via a feedback loop.
Topics: Adenocarcinoma of Lung; Cell Line, Tumor; Cell Movement; Epithelial-Mesenchymal Transition; Feedback; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nicotine; Oncogene Proteins; Protein Phosphatase 1; Repressor Proteins; Sp1 Transcription Factor; Transcription Factors | 2022 |
Associations of biomarkers for exposure to tobacco smoke with lung cancer risk in Korea.
Topics: Biomarkers; Humans; Lung Neoplasms; Nicotiana; Nicotine; Republic of Korea; Smoking; Tobacco Smoke Pollution | 2022 |
Flavored E-cigarette product aerosols induce transformation of human bronchial epithelial cells.
Topics: Adolescent; Cell Transformation, Neoplastic; Electronic Nicotine Delivery Systems; Epithelial Cells; Humans; Lung Neoplasms; Nicotine; Respiratory Aerosols and Droplets; Tobacco Products | 2023 |
Acetylcholine promotes chronic stress-induced lung adenocarcinoma progression via α5-nAChR/FHIT pathway.
Topics: Acetylcholine; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Lung Neoplasms; Mice; Nicotine; Receptors, Nicotinic; Signal Transduction; Tumor Microenvironment | 2023 |
Nicotine activates HIF-1α and regulates acid extruders through the nicotinic acetylcholine receptor to promote the Warburg effect in non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Nicotine; Receptors, Nicotinic | 2023 |
JWA inhibits nicotine-induced lung cancer stemness and progression through CHRNA5/AKT-mediated JWA/SP1/CD44 axis.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Electronic Nicotine Delivery Systems; Gene Expression Regulation, Neoplastic; Humans; Hyaluronan Receptors; Lung Neoplasms; Nerve Tissue Proteins; Nicotine; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic; Sp1 Transcription Factor | 2023 |
Comparative analyses of transcriptome sequencing and carcinogenic exposure toxicity of nicotine and 6-methyl nicotine in human bronchial epithelial cells.
Topics: Bronchi; Carcinogenesis; Carcinogens; Electronic Nicotine Delivery Systems; Epithelial Cells; Humans; Lung Neoplasms; Nicotine; Transcriptome | 2023 |
Electronic-cigarette smoke induces lung adenocarcinoma and bladder urothelial hyperplasia in mice.
Topics: Adenocarcinoma of Lung; Animals; DNA Damage; DNA Repair; Electronic Nicotine Delivery Systems; Hyperplasia; Lung; Lung Neoplasms; Male; Mice; Nicotine; Smoke; Smoking; Urinary Bladder; Urothelium | 2019 |
Nazartinib in EGFR Thr790Met-mutant non-small-cell lung cancer.
Topics: Adult; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; ErbB Receptors; Humans; Lung Neoplasms; Nicotine | 2020 |
Nicotine exposure potentiates lung tumorigenesis by perturbing cellular surveillance.
Topics: Animals; Carcinogenesis; Epithelial Cells; Humans; Lung Neoplasms; Mice; Nicotine | 2020 |
Inhaled nicotine and lung cancer: Potential role of the nicotinic acetylcholine receptor.
Topics: Adenocarcinoma of Lung; Animals; Hyperplasia; Lung Neoplasms; Mice; Nicotine; Receptors, Nicotinic; Smoke; Smoking; Urinary Bladder | 2020 |
Metabolomics Profiles of Smokers from Two Ethnic Groups with Differing Lung Cancer Risk.
Topics: Adult; Chromatography, Liquid; Ethnicity; Humans; Lung Neoplasms; Metabolomics; Middle Aged; Molecular Structure; Nicotine; Risk Factors; Smokers; Tandem Mass Spectrometry | 2020 |
An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells.
Topics: A549 Cells; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cisplatin; Drug Resistance, Neoplasm; Enzyme Activation; Humans; Lung Neoplasms; Models, Molecular; Molecular Docking Simulation; Nicotine; Okadaic Acid; Protein Phosphatase 2 | 2020 |
Nicotine promotes brain metastasis by polarizing microglia and suppressing innate immune function.
Topics: Animals; Antigens, Differentiation; Brain Neoplasms; Cell Line, Tumor; Chemokine CCL20; Female; Humans; Immunity, Innate; Insulin-Like Growth Factor I; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Microglia; Neoplasm Metastasis; Neoplasm Proteins; Nicotine; Receptors, Immunologic; Smoking Cessation Agents | 2020 |
Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme.
Topics: Alleles; Cytochrome P-450 CYP2A6; Genome-Wide Association Study; Humans; Linkage Disequilibrium; Lung Neoplasms; Male; Middle Aged; Nerve Tissue Proteins; Nicotine; Polymorphism, Single Nucleotide; Pulmonary Disease, Chronic Obstructive; Receptors, Nicotinic; Risk Factors; Smoking; Smoking Cessation | 2020 |
Nicotine dependence as a risk factor for upper aerodigestive tract (UADT) cancers: A mediation analysis.
Topics: Aged; Case-Control Studies; Female; Head and Neck Neoplasms; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Ontario; Risk Assessment; Risk Factors; Time Factors; Tobacco Use Disorder | 2020 |
Low-Dose Nicotine Activates EGFR Signaling via α5-nAChR and Promotes Lung Adenocarcinoma Progression.
Topics: Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Epithelial-Mesenchymal Transition; ErbB Receptors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Neoplasm Recurrence, Local; Nicotine; Phosphorylation; Receptors, Nicotinic; Signal Transduction; Tobacco Smoke Pollution; Up-Regulation; Xenograft Model Antitumor Assays | 2020 |
The Influence of Tobacco Smoke/Nicotine on CYP2A Expression in Human and African Green Monkey Lungs.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Chlorocebus aethiops; Datasets as Topic; Disease Models, Animal; Gene Expression Profiling; Humans; Lung; Lung Neoplasms; Male; Microsomes, Liver; Nicotiana; Nicotine; Non-Smokers; RNA, Messenger; Sequence Analysis, RNA; Smoke; Smokers; Smoking; Steroid Hydroxylases; Tobacco Smoke Pollution | 2020 |
Better treatments for lung cancer that spreads to the brain.
Topics: Anaplastic Lymphoma Kinase; Animals; Antibodies, Monoclonal, Humanized; B7-H1 Antigen; Brain; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cognition Disorders; ErbB Receptors; Humans; Immunotherapy; Lung Neoplasms; Mice; Molecular Targeted Therapy; Neoplasm Metastasis; Nicotine; Radiotherapy; Smoking; Survival Analysis | 2020 |
Nicotine promotes breast cancer metastasis by stimulating N2 neutrophils and generating pre-metastatic niche in lung.
Topics: Animals; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Lipocalin-2; Lung; Lung Neoplasms; Mice; Neoplasm Metastasis; Neutrophil Infiltration; Neutrophils; Nicotine; Smoking; STAT3 Transcription Factor | 2021 |
Association of CYP2A6 activity with lung cancer incidence in smokers: The multiethnic cohort study.
Topics: Aged; Cytochrome P-450 CYP2A6; Female; Follow-Up Studies; Genetic Variation; Genotype; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Prospective Studies; Risk; Smoke; Smoking; Tobacco Products | 2017 |
α9- and α7-containing receptors mediate the pro-proliferative effects of nicotine in the A549 adenocarcinoma cell line.
Topics: A549 Cells; Adenocarcinoma; alpha7 Nicotinic Acetylcholine Receptor; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Nicotine; Quaternary Ammonium Compounds; Receptors, Nicotinic; Stilbenes; Structure-Activity Relationship | 2018 |
Reciprocal activation of α5-nAChR and STAT3 in nicotine-induced human lung cancer cell proliferation.
Topics: Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Promoter Regions, Genetic; Receptors, Nicotinic; Signal Transduction; STAT3 Transcription Factor | 2017 |
Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN.
Topics: Animals; Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Carcinoma, Non-Small-Cell Lung; Disease Models, Animal; Hyperalgesia; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Nicotine; Paclitaxel; Peripheral Nervous System Diseases; Receptors, Cholinergic; Taxoids | 2018 |
Nicotine upregulates FGFR3 and RB1 expression and promotes non-small cell lung cancer cell proliferation and epithelial-to-mesenchymal transition via downregulation of miR-99b and miR-192.
Topics: A549 Cells; Animals; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Dose-Response Relationship, Drug; Down-Regulation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MicroRNAs; Nicotine; Nicotinic Agonists; Rats; Receptor, Fibroblast Growth Factor, Type 3; Retinoblastoma Binding Proteins; Ubiquitin-Protein Ligases; Up-Regulation | 2018 |
Nicotine inhibits CD24 expression in Lewis lung carcinoma cells by upregulation of RAS expression.
Topics: Animals; Biomarkers, Tumor; Carcinoma, Lewis Lung; CD24 Antigen; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Neoplastic Stem Cells; Nicotine; Prognosis; ras Proteins; Survival Analysis; Xenograft Model Antitumor Assays | 2018 |
Nicotine enhances store‑operated calcium entry by upregulating HIF‑1α and SOCC components in non‑small cell lung cancer cells.
Topics: Apoptosis; Biomarkers, Tumor; Calcium Channels; Calcium Signaling; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Nicotine; TRPC Cation Channels; Tumor Cells, Cultured | 2018 |
A Randomized Trial to Test Personalized Environmental Report Back to Reduce Lung Cancer Risk.
Topics: Air Pollution, Indoor; Environmental Monitoring; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Radon; Risk Reduction Behavior; Surveys and Questionnaires; Tobacco Smoke Pollution | 2019 |
The underestimated danger of E-cigarettes - also in the absence of nicotine.
Topics: Animals; Cigarette Smoking; Electronic Nicotine Delivery Systems; Humans; Lung Neoplasms; Nicotine; Smoking | 2018 |
Parthenolide inhibits tumor-promoting effects of nicotine in lung cancer by inducing P53 - dependent apoptosis and inhibiting VEGF expression.
Topics: A549 Cells; Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neovascularization, Pathologic; Nicotine; Real-Time Polymerase Chain Reaction; Sesquiterpenes; Tumor Suppressor Protein p53; Vascular Endothelial Growth Factor A | 2018 |
HDAC1 is indirectly involved in the epigenetic regulation of p38 MAPK that drive the lung cancer progression.
Topics: Animals; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Histone Deacetylase 1; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice; Neoplasms, Experimental; Nicotine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Urokinase Plasminogen Activator; Smoke | 2018 |
Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer.
Topics: Adaptor Proteins, Signal Transducing; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Self Renewal; Computer Simulation; E2F1 Transcription Factor; Electronic Nicotine Delivery Systems; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplastic Stem Cells; Nicotine; Octamer Transcription Factor-3; Phosphoproteins; Promoter Regions, Genetic; Protein Binding; Receptors, Nicotinic; RNA, Small Interfering; SOXB1 Transcription Factors; src-Family Kinases; Transcription Factors; YAP-Signaling Proteins | 2018 |
Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.
Topics: A549 Cells; AC133 Antigen; Adenocarcinoma of Lung; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cystic Fibrosis Transmembrane Conductance Regulator; Epithelial Cells; Humans; Lung; Lung Neoplasms; Mutation; Neoplastic Stem Cells; Nicotine; Signal Transduction | 2018 |
High-nicotine dependent smokers less likely to quit after screening.
Topics: Early Detection of Cancer; Humans; Lung Neoplasms; Nicotine; Smokers; Smoking Cessation; Tobacco Use Disorder | 2018 |
Effect of preoperative smoking cessation on postoperative pain outcomes in elderly patients with high nicotine dependence.
Topics: Aged; Analgesics, Opioid; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Preoperative Period; Smoking Cessation; Sufentanil; Thoracoscopy; Tobacco Use Disorder | 2019 |
Downregulation of miR-218 by nicotine promotes cell proliferation through targeting CDK6 in non-small cell lung cancer.
Topics: Aged; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cyclin-Dependent Kinase 6; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; MicroRNAs; Middle Aged; Nicotine | 2019 |
The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal.
Topics: A549 Cells; alpha7 Nicotinic Acetylcholine Receptor; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Tolerance; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nicotine; Nicotinic Agonists; Paclitaxel; Peripheral Nervous System Diseases; Piperazines; Reward | 2019 |
Nicotinic receptor β2 determines NK cell-dependent metastasis in a murine model of metastatic lung cancer.
Topics: Animals; Base Sequence; Disease Models, Animal; DNA Primers; Female; Killer Cells, Natural; Lung Neoplasms; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Nicotine; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction | 2013 |
Nicotine induces resistance to epidermal growth factor receptor tyrosine kinase inhibitor by α1 nicotinic acetylcholine receptor-mediated activation in PC9 cells.
Topics: Adenocarcinoma; Apoptosis; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Female; Flow Cytometry; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mitogen-Activated Protein Kinases; Nicotine; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic; Small Cell Lung Carcinoma; Tumor Cells, Cultured | 2013 |
Myeloid clusters are associated with a pro-metastatic environment and poor prognosis in smoking-related early stage non-small cell lung cancer.
Topics: Aged; Aged, 80 and over; Anthracosis; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Female; Humans; Lung Neoplasms; Lymph Nodes; Lymphatic Metastasis; Macrophages; Male; Middle Aged; Myeloid Cells; Neoplasm Staging; Nicotine; Phenotype; Prognosis; Smoking; STAT3 Transcription Factor | 2013 |
β-Blockers and metastasis in non-small-cell lung cancer.
Topics: Adrenergic beta-Antagonists; Animals; Carcinoma, Non-Small-Cell Lung; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Neoplasms; Nicotine; Propranolol; Protective Agents; Pulmonary Disease, Chronic Obstructive; Stress, Psychological | 2013 |
Tobacco-specific N-nitrosamine exposures and cancer risk in the Shanghai Cohort Study: remarkable coherence with rat tumor sites.
Topics: Animals; Asian People; Case-Control Studies; China; Cohort Studies; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Molecular Structure; Multivariate Analysis; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Rats; Risk Factors; Smoking | 2014 |
Carbonic anhydrase IX is associated with early pulmonary spreading of primary colorectal carcinoma and tobacco smoking.
Topics: Adult; Aged; Antigens, Neoplasm; Biomarkers; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma; Colorectal Neoplasms; Female; Ganglionic Stimulants; HT29 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Nicotine; Phosphorylation; Prognosis; Retrospective Studies; Smoking; STAT3 Transcription Factor | 2014 |
Reusable floating-electrode sensor for the quantitative electrophysiological monitoring of a nonadherent cell.
Topics: Cell Line, Tumor; Electrodes; Electrophysiology; Equipment Reuse; Humans; Lung Neoplasms; Nanotubes, Carbon; Nicotine; Receptors, Nicotinic; Semiconductors; Small Cell Lung Carcinoma | 2014 |
Nicotine increases the resistance of lung cancer cells to cisplatin through enhancing Bcl-2 stability.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cisplatin; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Mice; Nicotine; Protein Processing, Post-Translational; Protein Stability; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured; Ubiquitination; Up-Regulation | 2014 |
Flavonoid components in Scutellaria baicalensis inhibit nicotine-induced proliferation, metastasis and lung cancer-associated inflammation in vitro.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Line, Tumor; Cell Proliferation; Flavanones; Flavonoids; Gene Expression Regulation, Neoplastic; Humans; In Vitro Techniques; Inflammation; Lung Neoplasms; Neoplasm Metastasis; Nicotine; Plant Extracts; Scutellaria baicalensis | 2014 |
NeuroD1 mediates nicotine-induced migration and invasion via regulation of the nicotinic acetylcholine receptor subunits in a subset of neural and neuroendocrine carcinomas.
Topics: Basic Helix-Loop-Helix Transcription Factors; Bronchi; Calcium; Carcinoma, Neuroendocrine; Cell Differentiation; Cell Line, Tumor; Cell Movement; Clone Cells; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Models, Biological; Mutation; Neoplasm Invasiveness; Nerve Tissue Proteins; Nicotine; Protein Subunits; Receptor, trkB; Receptors, Nicotinic; Tumor Suppressor Protein p53; Up-Regulation | 2014 |
α5 Nicotinic acetylcholine receptor mediates nicotine-induced HIF-1α and VEGF expression in non-small cell lung cancer.
Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Male; Middle Aged; Nicotine; Receptors, Nicotinic; Vascular Endothelial Growth Factor A | 2014 |
Cigarette smoking and systemic therapy for lung cancer: considering the evidence to improve cancer care.
Topics: Antineoplastic Agents; Enzyme Induction; Humans; Lung Neoplasms; Nicotine; Smoking | 2014 |
Nicotine and oxidative stress induced exomic variations are concordant and overrepresented in cancer-associated genes.
Topics: Adenocarcinoma; Base Sequence; Carcinogens; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line; Exome; Humans; Hydrogen Peroxide; INDEL Mutation; Lung Neoplasms; Microsatellite Repeats; Mucin-2; Mucin-4; Mucins; Mutation; Neoplasms; Nicotine; Oxidants; Oxidative Stress; Sequence Analysis, DNA; Smoking | 2014 |
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Glutathione S-Transferase pi; Humans; Inhibitor of Differentiation Protein 1; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Promoter Regions, Genetic; Repressor Proteins; RNA, Small Interfering; Stathmin; Transcription Factors; Up-Regulation; Wound Healing | 2014 |
Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist.
Topics: Acetylcholine; Alanine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Conotoxins; Conus Snail; Humans; Lung Neoplasms; Molecular Dynamics Simulation; Mutagenesis; Nicotine; Nicotinic Antagonists; Oocytes; Receptors, Nicotinic; Xenopus | 2015 |
β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition.
Topics: Animals; Arrestins; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Cell Line, Tumor; E2F1 Transcription Factor; Epithelial-Mesenchymal Transition; Fibronectins; Homeodomain Proteins; Humans; Lung Neoplasms; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Nicotine; Receptors, Nicotinic; Retinoblastoma Protein; Signal Transduction; Tight Junctions; Transcription Factors; Vimentin; Zinc Finger E-box-Binding Homeobox 1 | 2015 |
Nicotine induces resistance to erlotinib via cross-talk between α 1 nAChR and EGFR in the non-small cell lung cancer xenograft model.
Topics: Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice, Inbred BALB C; Mice, Nude; Nicotine; Nicotinic Agonists; Receptor Cross-Talk; Receptors, Nicotinic; Smoking; Xenograft Model Antitumor Assays | 2015 |
Nuciferine, extracted from Nelumbo nucifera Gaertn, inhibits tumor-promoting effect of nicotine involving Wnt/β-catenin signaling in non-small cell lung cancer.
Topics: Animals; Apoptosis; Aporphines; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Drugs, Chinese Herbal; Humans; Lung Neoplasms; Male; Medicine, Chinese Traditional; Mice, Inbred BALB C; Mice, Nude; Nelumbo; Neoplasm Transplantation; Nicotine; Plant Leaves; Wnt Signaling Pathway | 2015 |
Chronic nicotine exposure mediates resistance to EGFR-TKI in EGFR-mutated lung cancer via an EGFR signal.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Disease-Free Survival; Drug Resistance, Neoplasm; ErbB Receptors; Female; Gefitinib; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Middle Aged; Mutation; Nicotine; Quinazolines; Receptors, Nicotinic; Signal Transduction; Smoking | 2015 |
Biomarkers of tobacco smoke exposure in racial/ethnic groups at high risk for lung cancer.
Topics: Adolescent; Adult; Biomarkers; Cotinine; Female; Hawaii; Humans; Lung Neoplasms; Male; Mass Spectrometry; Native Hawaiian or Other Pacific Islander; Nicotine; Philippines; Risk; Saliva; Smoking; Translational Research, Biomedical; White People | 2015 |
Mechanisms of tumor-promoting activities of nicotine in lung cancer: synergistic effects of cell membrane and mitochondrial nicotinic acetylcholine receptors.
Topics: Cell Line, Transformed; Cell Line, Tumor; Cell Membrane; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mitochondria; Nicotine; Receptors, Nicotinic | 2015 |
α5-nAChR modulates nicotine-induced cell migration and invasion in A549 lung cancer cells.
Topics: Blotting, Western; Cadherins; Cell Culture Techniques; Cell Line, Tumor; Cell Movement; Gene Expression; Gene Silencing; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering | 2015 |
Effects of Physalis peruviana L on Toxicity and Lung Cancer Induction by Nicotine Derived Nitrosamine Ketone in Rats.
Topics: Animals; Body Weight; Carcinogenesis; Flow Cytometry; Immunoenzyme Techniques; Ketones; Lung Neoplasms; Male; Nicotine; Nicotinic Agonists; Nitrosamines; Physalis; Plant Extracts; Protective Agents; Rats; Rats, Sprague-Dawley | 2015 |
Early and delayed intervention with rapamycin prevents NNK-induced lung adenocarcinoma in A/J mice.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; bcl-X Protein; Carcinogens; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Nicotiana; Nicotine; Nitrosamines; Proliferating Cell Nuclear Antigen; Ribosomal Protein S6 Kinases, 90-kDa; Sirolimus; TOR Serine-Threonine Kinases | 2015 |
Bromoenol Lactone Attenuates Nicotine-Induced Breast Cancer Cell Proliferation and Migration.
Topics: Animals; Anticarcinogenic Agents; Carcinogens; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial Cells; Female; Gene Expression Regulation, Neoplastic; Group VI Phospholipases A2; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Naphthalenes; Nicotine; Platelet Endothelial Cell Adhesion Molecule-1; Pyrones; Signal Transduction; Transcriptional Activation; Xenograft Model Antitumor Assays | 2015 |
Nicotinic acetylcholine receptor expression in human airway correlates with lung function.
Topics: Adult; Aged; Cell Line, Tumor; Epithelial Cells; Female; Gene Expression; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Nicotine; Receptors, Nicotinic; Respiratory Physiological Phenomena; Smoking | 2016 |
Genetic determinants of cytochrome P450 2A6 activity and biomarkers of tobacco smoke exposure in relation to risk of lung cancer development in the Shanghai cohort study.
Topics: Asian People; Biomarkers, Tumor; Case-Control Studies; China; Cohort Studies; Cotinine; Cytochrome P-450 CYP2A6; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Odds Ratio; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Risk Factors; Smoking | 2016 |
Genetic determinants of CYP2A6 activity across racial/ethnic groups with different risks of lung cancer and effect on their smoking intensity.
Topics: Adult; Aged; Chromatography, Liquid; Cohort Studies; Cytochrome P-450 CYP2A6; Ethnicity; Female; Genetic Variation; Genotype; Humans; Lung Neoplasms; Male; Mass Spectrometry; Middle Aged; Nicotine; Oligonucleotide Array Sequence Analysis; Risk Factors; Smoking | 2016 |
[Nicotine Induced Lung Cancer Cells Epithelial-mesenchymal Transition
and Promote Its Vitro Invasion Potential].
Topics: A549 Cells; beta Catenin; Cadherins; Cell Movement; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Vimentin | 2016 |
In vitro effects of nicotine on the non-small-cell lung cancer line A549.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Cell Proliferation; Humans; In Vitro Techniques; Lung Neoplasms; Microscopy, Electron; Microscopy, Fluorescence; Nicotine; Nicotinic Agonists | 2016 |
Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors.
Topics: A549 Cells; Adenocarcinoma; alpha7 Nicotinic Acetylcholine Receptor; Carcinoma, Non-Small-Cell Lung; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; E2F1 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Neoplasm Proteins; Nicotine; Smoking; STAT1 Transcription Factor | 2016 |
Role of α7-nicotinic acetylcholine receptor in nicotine-induced invasion and epithelial-to-mesenchymal transition in human non-small cell lung cancer cells.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Carcinogenesis; Carcinoma, Non-Small-Cell Lung; Cell Movement; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; MAP Kinase Signaling System; Nicotine; RNA, Small Interfering; Tumor Cells, Cultured | 2016 |
Discovery of (R,E)-N-(7-Chloro-1-(1-[4-(dimethylamino)but-2-enoyl]azepan-3-yl)-1H-benzo[d]imidazol-2-yl)-2-methylisonicotinamide (EGF816), a Novel, Potent, and WT Sparing Covalent Inhibitor of Oncogenic (L858R, ex19del) and Resistant (T790M) EGFR Mutants
Topics: Animals; Antineoplastic Agents; Benzimidazoles; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; ErbB Receptors; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Models, Molecular; Molecular Conformation; Mutation; Neoplasms, Experimental; Nicotine; Protein Kinase Inhibitors; Rats; Rats, Wistar; Structure-Activity Relationship | 2016 |
Differences in Toxicological and Pharmacological Responses Mediated by Polymorphic Cytochromes P450 and Related Drug-Metabolizing Enzymes.
Topics: Animals; Cytochrome P-450 Enzyme System; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Humans; Inactivation, Metabolic; Liver; Lung Neoplasms; Nicotine; Pharmaceutical Preparations; Polymorphism, Genetic; Polypharmacy; Risk; Species Specificity | 2017 |
Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6.
Topics: Biomarkers; Cotinine; Cytochrome P-450 CYP2A6; Ethnicity; Genetic Variation; Glucuronosyltransferase; Humans; Lung Neoplasms; Nicotine; Oxygenases; Smoking | 2017 |
Variation in CYP2A6 and nicotine metabolism among two American Indian tribal groups differing in smoking patterns and risk for tobacco-related cancer.
Topics: Adult; Aged; Aged, 80 and over; Arizona; Cytochrome P-450 CYP2A6; Female; Humans; Indians, North American; Lung Neoplasms; Male; Middle Aged; Nicotine; Odds Ratio; Pharmacogenomic Variants; Phenotype; Smoking; South Dakota; Young Adult | 2017 |
CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.
Topics: Asian People; Biomarkers; Carcinogens; Case-Control Studies; Cytochrome P-450 CYP2A6; Female; Genotype; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Polymorphism, Genetic; Prospective Studies; Risk; Singapore; Smoke; Smoking | 2017 |
Activated cholinergic signaling provides a target in squamous cell lung carcinoma.
Topics: Acetylcholine; Adaptor Proteins, Signal Transducing; Animals; Benzofurans; Blotting, Western; Calcium; Carcinoma, Squamous Cell; Cell Proliferation; Cells, Cultured; Choline O-Acetyltransferase; Electrophysiology; GPI-Linked Proteins; Humans; Lung; Lung Neoplasms; Male; Membrane Glycoproteins; Mice; Mice, Nude; Muscarinic Antagonists; Nicotine; Phosphorylation; Pyrrolidines; Receptor, Muscarinic M3; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Vesicular Acetylcholine Transport Proteins | 2008 |
Nicotine induces resistance to chemotherapy by modulating mitochondrial signaling in lung cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; bcl-2-Associated X Protein; Carcinogens; Caspase 9; Cell Line, Tumor; Cisplatin; Drug Resistance, Neoplasm; Etoposide; Humans; Lung Neoplasms; MAP Kinase Kinase 1; MAP Kinase Kinase 2; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Nicotine; Nicotinic Agonists; Protein Transport; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Smoking | 2009 |
Nicotine promotes mammary tumor migration via a signaling cascade involving protein kinase C and CDC42.
Topics: Animals; Breast; Breast Neoplasms; cdc42 GTP-Binding Protein; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Humans; Lung Neoplasms; Mice; Nicotine; Protein Kinase C-alpha; Signal Transduction | 2008 |
Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.
Topics: Adult; Aged; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nerve Tissue Proteins; Nicotine; Nitrosamines; Polymorphism, Single Nucleotide; Pyridines; Receptors, Nicotinic; Smoking | 2008 |
Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer.
Topics: Adult; Asian People; Cross-Sectional Studies; Diet; Female; Hawaii; Humans; Interviews as Topic; Logistic Models; Los Angeles; Lung Neoplasms; Male; Middle Aged; Native Hawaiian or Other Pacific Islander; Nicotine; Risk; Smoking; Surveys and Questionnaires; White People | 2008 |
Role of alpha7-nicotinic acetylcholine receptor in human non-small cell lung cancer proliferation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Apoptosis; Bungarotoxins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cobra Neurotoxin Proteins; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Ligands; Lung Neoplasms; Male; Mice; Mice, SCID; Models, Biological; Nicotine; Proto-Oncogene Proteins c-raf; Receptors, Nicotinic; Ribosomal Protein S6 Kinases, 90-kDa; Tubocurarine; Xenograft Model Antitumor Assays | 2008 |
[Diagnosis of lung cancer: an opportunity for smoking cessation?].
Topics: Antidepressive Agents; Humans; Lung Neoplasms; Nicotine; Nicotinic Agonists; Smoking; Smoking Cessation | 2008 |
Second hand smoke exposure and excess heart disease and lung cancer mortality among hospital staff in Crete, Greece: a case study.
Topics: Adult; Air Pollution, Indoor; Environmental Monitoring; Epidemiological Monitoring; Greece; Heart Diseases; Hospital Units; Hospitals, Public; Humans; Law Enforcement; Lung Neoplasms; Middle Aged; Nicotine; Occupational Exposure; Organizational Case Studies; Particulate Matter; Personnel, Hospital; Prevalence; Risk Assessment; Tobacco Smoke Pollution | 2008 |
FOXO3a elicits a pro-apoptotic transcription program and cellular response to human lung carcinogen nicotine-derived nitrosaminoketone (NNK).
Topics: Adenocarcinoma; Apoptosis; Carcinogens; Cell Line, Tumor; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Transcription, Genetic; Tumor Suppressor Proteins | 2010 |
Cigarette smoke extract induces activation of beta-catenin/TCF signaling through inhibiting GSK3beta in human alveolar epithelial cell line.
Topics: Active Transport, Cell Nucleus; beta Catenin; Cell Line, Tumor; Cell Nucleus; Cell Survival; Enzyme Inhibitors; Epithelial Cells; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Pulmonary Alveoli; Signal Transduction; Smoke; Tars | 2009 |
Cigarette sidestream smoke induces phosphorylated histone H2AX.
Topics: Cell Survival; DNA; Histones; Humans; Lung Neoplasms; Nicotine; Phosphorylation; Smoke; Smoking | 2009 |
Cost-effectiveness of varenicline compared with nicotine patches for smoking cessation--results from four European countries.
Topics: Adolescent; Adult; Aged; Benzazepines; Cost-Benefit Analysis; Europe; Female; Heart Diseases; Humans; Incidence; Lung Neoplasms; Male; Markov Chains; Middle Aged; Models, Statistical; Nicotine; Nicotinic Agonists; Pulmonary Disease, Chronic Obstructive; Quality-Adjusted Life Years; Quinoxalines; Smoking; Smoking Cessation; Stroke; Varenicline; Young Adult | 2009 |
Is nicotine the estrogen of lung cancer?
Topics: alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Carcinogens; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Lung; Lung Neoplasms; Nicotine; Nitrosamines; Prognosis; Receptors, Nicotinic; Risk Factors; Tobacco Smoke Pollution | 2009 |
Does nicotine replacement therapy cause cancer? Evidence from the Lung Health Study.
Topics: Administration, Cutaneous; Adult; Female; Gastrointestinal Neoplasms; Humans; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Nicotine; Nicotinic Agonists; Proportional Hazards Models; Regression Analysis; Risk Factors; Smoking; Smoking Cessation; Young Adult | 2009 |
Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.
Topics: Aged; Asian; Carcinogens; Cross-Sectional Studies; Ethnicity; Female; Follow-Up Studies; Glucuronates; Hawaii; Humans; Inactivation, Metabolic; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Prognosis; Pyridines; Risk Factors; Smoking; Survival Rate; White People | 2009 |
Nicotine stimulates PPARbeta/delta expression in human lung carcinoma cells through activation of PI3K/mTOR and suppression of AP-2alpha.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Bungarotoxins; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cholinergic Agonists; Enzyme Activation; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Models, Biological; Nicotine; Phosphatidylinositol 3-Kinases; PPAR delta; PPAR-beta; Promoter Regions, Genetic; Protein Kinases; Receptors, Nicotinic; TOR Serine-Threonine Kinases; Transcription Factor AP-2; Tumor Cells, Cultured; Up-Regulation | 2009 |
Less-toxic cigarette use may backfire.
Topics: Heart Diseases; Humans; Lung Neoplasms; Nicotine; Risk Factors; Smoking; Stroke; Tobacco Use Disorder | 2009 |
Nicotine promotes tumor growth and metastasis in mouse models of lung cancer.
Topics: Animals; Carcinogens; Cell Proliferation; Disease Progression; Epithelium; Female; Lung; Lung Neoplasms; Mesoderm; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Nicotine; Nicotinic Agonists; Recurrence | 2009 |
Are smokers now at higher risk of bladder cancer? Are changes in cigarettes to blame?
Topics: Humans; Incidence; Lung Neoplasms; Nicotiana; Nicotine; Risk Assessment; Risk Factors; Smoking; Tobacco Industry; United States; United States Food and Drug Administration; Urinary Bladder Neoplasms | 2009 |
Nicotine enhances the antiapoptotic function of Mcl-1 through phosphorylation.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Drug Resistance, Neoplasm; Enzyme Activation; Flavonoids; Half-Life; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myeloid Cell Leukemia Sequence 1 Protein; Nicotine; Phosphorylation; Phosphothreonine; Propranolol; Proto-Oncogene Proteins c-bcl-2; Receptors, Adrenergic, beta | 2009 |
Sex differences in susceptibility to carcinogens.
Topics: Carcinogens; Cytochrome P-450 Enzyme System; Disease Susceptibility; DNA Adducts; DNA Repair; Estrogens; Female; Humans; Lung; Lung Neoplasms; Male; Nicotine; Pulmonary Disease, Chronic Obstructive; Receptors, Estrogen; Risk Factors; Sex Factors | 2009 |
ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus.
Topics: Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Carcinoma; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Lung Neoplasms; Multigene Family; Nerve Tissue Proteins; Nicotine; Promoter Regions, Genetic; Protein Subunits; Receptors, Nicotinic; Small Cell Lung Carcinoma; Smoking; Transcriptional Activation | 2010 |
DNA damage response induced by exposure of human lung adenocarcinoma cells to smoke from tobacco- and nicotine-free cigarettes.
Topics: Adenocarcinoma; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Line; DNA Breaks, Double-Stranded; DNA Repair; DNA-Binding Proteins; G1 Phase; Histones; Humans; Lung Neoplasms; Mutagenicity Tests; Nicotiana; Nicotine; Phosphorylation; Protein Serine-Threonine Kinases; Reactive Oxygen Species; S Phase; Smoke; Tumor Suppressor Proteins | 2010 |
Repetitive nicotine exposure leads to a more malignant and metastasis-prone phenotype of SCLC: a molecular insight into the importance of quitting smoking during treatment.
Topics: Animals; Carcinoma, Small Cell; Cell Adhesion; Chemokine CXCL12; Drug Resistance, Neoplasm; Female; Humans; Lung Neoplasms; Mice; Neoplasm Metastasis; Nicotine; Phenotype; Receptors, CXCR4; Receptors, Nicotinic; Smoking Cessation | 2010 |
Nicotine-induced survival signaling in lung cancer cells is dependent on their p53 status while its down-regulation by curcumin is independent.
Topics: Cell Line, Tumor; Cell Proliferation; Curcumin; Cyclin D1; Cyclooxygenase 2; Down-Regulation; Humans; Lung Neoplasms; Nicotine; Phosphorylation; Proto-Oncogene Proteins c-akt; Signal Transduction; Transcription Factor AP-1; Tumor Suppressor Protein p53 | 2010 |
Nicotine stimulated dendritic cells could achieve anti-tumor effects in mouse lung and liver cancer.
Topics: Animals; Antigens, CD; B7-1 Antigen; Bone Marrow Cells; Dendritic Cells; Female; Flow Cytometry; Immunotherapy; Liver Neoplasms; Lung Neoplasms; Lymphocyte Activation; Major Histocompatibility Complex; Mice; Mice, Inbred C57BL; Nicotine; T-Lymphocytes; Up-Regulation | 2011 |
ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors.
Topics: Apoptosis; Arrestins; beta-Arrestin 1; beta-Arrestins; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; E2F Transcription Factors; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Immunoblotting; Immunoprecipitation; Lung; Lung Neoplasms; Microscopy, Confocal; Nicotine; Polymerase Chain Reaction; RNA, Messenger; Smoking; Up-Regulation | 2011 |
Nicotine inhibits cisplatin-induced apoptosis in NCI-H446 cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Cisplatin; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Nicotine; Nicotinic Agonists; Reverse Transcriptase Polymerase Chain Reaction; Survivin; X-Linked Inhibitor of Apoptosis Protein | 2012 |
Toenail nicotine level as a novel biomarker for lung cancer risk.
Topics: Adult; Aged; Biomarkers, Tumor; Case-Control Studies; Chi-Square Distribution; Health Personnel; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Nails; Nicotine; Prospective Studies; Risk Factors; Smoking; Statistics, Nonparametric; Surveys and Questionnaires; United States | 2011 |
[Hookah (shisha, narghile) smoking, cancer and the need for a critical medical anthropology].
Topics: Anthropology, Cultural; Carcinoembryonic Antigen; Humans; Lung Neoplasms; Nicotine; Risk Factors; Smoking | 2011 |
Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Adult; Aged; Case-Control Studies; Creatinine; Female; Humans; Individuality; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Oxidoreductases; Polymorphism, Single Nucleotide; Pyridines; Smoking; Tobacco Smoke Pollution | 2012 |
CHRNA5 as negative regulator of nicotine signaling in normal and cancer bronchial cells: effects on motility, migration and p63 expression.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Bronchi; Calcium; Cell Line; Cell Movement; Humans; Lung Neoplasms; Membrane Proteins; Nerve Tissue Proteins; Nicotine; Receptors, Nicotinic; Signal Transduction | 2011 |
ID1 facilitates the growth and metastasis of non-small cell lung cancer in response to nicotinic acetylcholine receptor and epidermal growth factor receptor signaling.
Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Movement; Cell Proliferation; Cells, Cultured; Disease Progression; DNA-Binding Proteins; Epidermal Growth Factor; ErbB Receptors; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Differentiation Protein 1; Lung; Lung Neoplasms; Neoplasm Metastasis; Neovascularization, Pathologic; Nicotine; Nicotinic Agonists; Protein Subunits; Receptors, Nicotinic; RNA, Small Interfering; Signal Transduction; src-Family Kinases; Transcription Factors; Vimentin | 2011 |
Chronic nicotine consumption does not influence 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis.
Topics: Adenoma; Animals; Carcinogens; Cells, Cultured; Drinking Water; Female; Guanine; Humans; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Nicotine; Nitrosamines | 2011 |
Nicotine does not enhance tumorigenesis in mutant K-ras-driven mouse models of lung cancer.
Topics: Adenocarcinoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Drinking Water; Female; Humans; Lung Neoplasms; Male; Mice; Mice, Inbred A; Mice, Inbred C57BL; Mutation; Nicotine; Nitrosamines; Proto-Oncogene Proteins p21(ras) | 2011 |
Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers.
Topics: Aged; China; Cotinine; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Nitrosamines; Phenanthrenes; Prospective Studies; Pyridines; Smoke; Smoking | 2011 |
Long-term nicotine replacement therapy: cancer risk in context.
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Lung Neoplasms; Male; Mutation; Nicotine; Nitrosamines; Proto-Oncogene Proteins p21(ras) | 2011 |
How do we safely get people to stop smoking?
Topics: Adenocarcinoma; Adenoma; Animals; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Female; Humans; Lung Neoplasms; Male; Mutation; Nicotine; Nitrosamines; Proto-Oncogene Proteins p21(ras) | 2011 |
Cooperative regulation of non-small cell lung carcinoma by nicotinic and beta-adrenergic receptors: a novel target for intervention.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; DNA, Neoplasm; Epinephrine; Extracellular Signal-Regulated MAP Kinases; gamma-Aminobutyric Acid; Humans; Lung Neoplasms; Molecular Targeted Therapy; Nicotine; Norepinephrine; Phosphorylation; Propranolol; Protein Subunits; Receptors, Adrenergic, beta; Receptors, Nicotinic | 2012 |
Is α7-nAChR a possible target for lung cancer and malignant pleural mesothelioma treatment?
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Delivery Systems; Humans; Lung Neoplasms; Mesothelioma; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pleural Neoplasms; Receptors, Nicotinic; Snake Venoms | 2012 |
IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Cell Survival; Humans; I-kappa B Kinase; Ketones; Lung Neoplasms; Nicotiana; Nicotine; Nitrosamines; Promoter Regions, Genetic; RNA Interference; RNA, Messenger; RNA, Small Interfering; Signal Transduction; Smoking; STAT3 Transcription Factor | 2013 |
Mitochondrial reactive oxygen species mediates nicotine-induced hypoxia-inducible factor-1α expression in human non-small cell lung cancer cells.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Dihydro-beta-Erythroidine; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mecamylamine; Mitochondria; Mitogen-Activated Protein Kinase 1; Nicotine; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptors, Cholinergic; RNA Interference; RNA, Small Interfering; Smoking; Transcription, Genetic | 2012 |
Nicotinic modulation of therapeutic response in vitro and in vivo.
Topics: Animals; Carbonic Anhydrases; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Male; Mice; Mice, Nude; Nicotine; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Random Allocation; Xenograft Model Antitumor Assays | 2012 |
[The smoker is a very sweet squirrel in cage].
Topics: France; Health Behavior; Humans; Lung Neoplasms; Metaphor; Nicotine; Smoking; Smoking Cessation; Tobacco Industry; Tobacco Use Disorder | 2012 |
Lung tumorigenesis promoted by anti-apoptotic effects of cotinine, a nicotine metabolite through activation of PI3K/Akt pathway.
Topics: Animals; Apoptosis; Aryl Hydrocarbon Hydroxylases; Caspase 3; Caspase 7; Cell Line; Cell Transformation, Neoplastic; Cotinine; Cytochrome P-450 CYP2A6; Female; Humans; Lung; Lung Neoplasms; Mice; Mice, Inbred A; Mice, Inbred C57BL; Nicotine; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt | 2012 |
β-cryptoxanthin restores nicotine-reduced lung SIRT1 to normal levels and inhibits nicotine-promoted lung tumorigenesis and emphysema in A/J mice.
Topics: Adenocarcinoma; Animals; Anticarcinogenic Agents; Carcinogens; Cell Transformation, Neoplastic; Cryptoxanthins; Drug Evaluation, Preclinical; Gene Expression Regulation; Lung; Lung Neoplasms; Male; Mice; Mice, Inbred Strains; Nicotine; Pulmonary Emphysema; Sirtuin 1; Xanthophylls | 2013 |
Silencing of periostin inhibits nicotine-mediated tumor cell growth and epithelial-mesenchymal transition in lung cancer cells.
Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cisplatin; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; RNA Interference; RNA, Messenger; RNA, Small Interfering; Snail Family Transcription Factors; Transcription Factors; Up-Regulation | 2013 |
Genotyping human CYP2A6 variants.
Topics: Aryl Hydrocarbon Hydroxylases; Chromosomes, Human, Pair 19; Cotinine; Cytochrome P-450 CYP2A6; Genotype; Humans; Isoenzymes; Lung Neoplasms; Mixed Function Oxygenases; Nicotine; Phenotype; Polymerase Chain Reaction; Polymorphism, Genetic; Racial Groups; Smoking | 2002 |
Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Bronchi; Carcinogens; Carrier Proteins; Cell Cycle Proteins; Cell Death; Cell Survival; Cells, Cultured; DNA-Binding Proteins; Enzyme Activation; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Forkhead Box Protein O1; Forkhead Transcription Factors; Glycogen Synthase Kinase 3; Humans; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Nicotiana; Nicotine; Nitrosamines; Phenotype; Phosphoproteins; Phosphorylation; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Time Factors; Transcription Factors; Ultraviolet Rays | 2003 |
BIOCHEMICAL EFFECTS OF TOBACCO SMOKE AND NICOTINE INHALATION.
Topics: Dietary Proteins; Drug Delivery Systems; Growth; Lung Neoplasms; Metabolism; Nicotiana; Nicotine; Rats; Research; Respiratory System; Smoke; Smoking; Tobacco Use Cessation Devices; Toxicology | 1963 |
[ON THE EFFECTS OF NICOTINE AND THEIR SEQUELAE IN THE TOBACCO HABIT].
Topics: Cardiovascular Diseases; Gastrointestinal Tract; Habits; Humans; Lung Neoplasms; Neoplasms; Nicotiana; Nicotine; Pharmacology; Smoking | 1963 |
[ON THE EFFECTS OF NICOTINE AND ITS CONSEQUENCES IN THE TOBACCO HABIT].
Topics: Adolescent; Amblyopia; Bronchitis; Cardiovascular Diseases; Child; Cough; Habits; Humans; Lung Neoplasms; Nicotiana; Nicotine; Peptic Ulcer; Pharmacology; Physiology; Pulmonary Emphysema; Smoking; Substance-Related Disorders; Tars; Toxicology | 1964 |
REDUCTION OF TUMORIGENICITY OF CIGARETTE SMOKE: AN EXPERIMENTAL APPROACH.
Topics: Aldehydes; Animals; Benzopyrenes; Carbon Monoxide; Carcinogens; Cilia; Formates; Lung Diseases; Lung Neoplasms; Mice; Mollusca; Neoplasms; Neoplasms, Experimental; Nicotiana; Nicotine; Papilloma; Phenols; Research; Skin Neoplasms; Smoke; Smoking; Tars | 1965 |
[ON THE EFFECTS OF TOBACCO SMOKING ON HEART, CIRCULATION AND LUNGS. REVIEW OF LITERATURE AND PERSONAL SUTDIES].
Topics: Air Pollution; Blood Gas Analysis; Bronchitis; Cardiovascular Diseases; Electrocardiography; Heart Function Tests; Humans; Hypersensitivity; Lung Neoplasms; Nicotine; Respiratory Function Tests; Smoking; Toxicology | 1965 |
The incidence of lung tumors in albino mice exposed to the smoke from cigarettes low in nicotine content.
Topics: Animals; Incidence; Lung Neoplasms; Mice; Nicotiana; Nicotine; Smoke; Smoking | 1955 |
Toxicological evaluation of propane expanded tobacco.
Topics: Administration, Inhalation; Administration, Topical; Animals; Carboxyhemoglobin; Carcinogenicity Tests; Chlorofluorocarbons, Methane; Female; Laryngeal Neoplasms; Lung; Lung Neoplasms; Male; Mutagens; Nicotiana; Nicotine; Propane; Rats; Rats, Sprague-Dawley; Salmonella typhimurium; Sex Characteristics; Sister Chromatid Exchange; Skin Neoplasms; Smoke | 2003 |
Smoking reduction and tobacco-related cancers: the more things change, the more they stay the same.
Topics: Biomarkers, Tumor; Carcinogens; Global Health; Humans; International Agencies; Lung Neoplasms; Neoplasms; Nicotine; Nicotinic Agonists; Nitrosamines; Risk Factors; Smoking; Smoking Cessation; Tobacco Smoke Pollution; Tobacco Use Disorder; United States | 2004 |
Nicotine induces multi-site phosphorylation of Bad in association with suppression of apoptosis.
Topics: Apoptosis; bcl-Associated Death Protein; Carrier Proteins; Cell Death; Cell Line, Tumor; Drug Resistance, Neoplasm; Humans; Lung Neoplasms; Nicotine; Nicotinic Agonists; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2004 |
Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes.
Topics: Adult; Aged; Biomarkers; Carcinogens; Cotinine; Female; Ganglionic Stimulants; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Nicotine; Polycyclic Aromatic Hydrocarbons; Smoke; Smoking; Tars | 2005 |
Tobacco components stimulate Akt-dependent proliferation and NFkappaB-dependent survival in lung cancer cells.
Topics: Carcinogens; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Proliferation; Cell Survival; Ganglionic Stimulants; Humans; Lung; Lung Neoplasms; NF-kappa B; Nicotine; Nitrosamines; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Smoking; Tumor Cells, Cultured | 2005 |
Urinary metabolites of a tobacco-specific lung carcinogen in nonsmoking hospitality workers.
Topics: Adolescent; Adult; Air Pollutants, Occupational; Biomarkers; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Interviews as Topic; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Pyridines; Restaurants; Tobacco Smoke Pollution; Workforce | 2005 |
Japanese spousal smoking study revisited: how a tobacco industry funded paper reached erroneous conclusions.
Topics: Adult; Conflict of Interest; Confounding Factors, Epidemiologic; Cotinine; Creatinine; Diet; Female; Humans; Japan; Life Style; Lung Neoplasms; Middle Aged; Nicotine; Reproducibility of Results; Research Design; Research Support as Topic; Saliva; Self Disclosure; Smoking; Spouses; Tobacco Industry; Tobacco Smoke Pollution | 2005 |
Nicotine withdrawal and nicotine replacement in the palliative care setting.
Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Adenoid Cystic; Carcinoma, Renal Cell; Female; Humans; Kidney Neoplasms; Lung Neoplasms; Nicotine; Nicotinic Agonists; Palliative Care; Parotid Neoplasms; Smoking; Smoking Cessation; Substance Withdrawal Syndrome | 2005 |
Protein kinase Ciota promotes nicotine-induced migration and invasion of cancer cells via phosphorylation of micro- and m-calpains.
Topics: Bungarotoxins; Calpain; Cell Movement; Cytoplasm; Humans; Isoenzymes; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Phosphorylation; Protein Kinase C; Wound Healing | 2006 |
Estradiol and nicotine exposure enhances A549 bronchioloalveolar carcinoma xenograft growth in mice through the stimulation of angiogenesis.
Topics: Adenocarcinoma, Bronchiolo-Alveolar; Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Endothelial Cells; Estradiol; Female; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Nicotine; Transplantation, Heterologous; Vascular Endothelial Growth Factor A | 2006 |
Pulmonary risks; the latest on lung cancer. Smokers and nonsmokers both need to know that genetics play a role, food can be a preventative, and new tests can lead to earlier diagnosis.
Topics: Brassica; Cheek; Early Diagnosis; Female; Humans; Isothiocyanates; Longevity; Lung Neoplasms; Male; Mouth Mucosa; Nicotine; Phytotherapy; Sex Factors; Smoking | 2006 |
Do reductions in the tar and nicotine yields of cigarettes help to explain recent reductions in lung cancer rates in young men and women in the United States?
Topics: Adult; Age Factors; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Risk Reduction Behavior; Smoke; Smoking; Tars; Time Factors; United States | 2006 |
[Influence of nicotine addiction on telomerase activity in malignant non-small cell lung tumors].
Topics: Adult; Biopsy, Fine-Needle; Carcinoma, Non-Small-Cell Lung; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Polymerase Chain Reaction; Telomerase; Tobacco Use Disorder | 2005 |
Cigarette smoking and lung cancer: modeling total exposure and intensity.
Topics: Age Distribution; Aged; Case-Control Studies; Confidence Intervals; Europe; Female; Humans; Incidence; Linear Models; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Nicotine; Odds Ratio; Probability; Retrospective Studies; Risk Assessment; Sex Distribution; Smoking; Survival Analysis; Time Factors | 2006 |
The cost utility of bupropion in smoking cessation health programs: simulation model results for Sweden.
Topics: Adult; Aged; Bupropion; Chewing Gum; Cost-Benefit Analysis; Dopamine Uptake Inhibitors; Female; Heart Failure; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Quality-Adjusted Life Years; Smoking Cessation; Stroke; Sweden | 2006 |
Nicotine prevents the apoptosis induced by menadione in human lung cancer cells.
Topics: Apoptosis; Cell Proliferation; Humans; Lung Neoplasms; NF-kappa B; Nicotine; RNA Interference; RNA, Messenger; Vitamin K 3 | 2006 |
Nicotine inhibits apoptosis induced by chemotherapeutic drugs by up-regulating XIAP and survivin.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Chromatin Immunoprecipitation; Cisplatin; Deoxycytidine; Dihydro-beta-Erythroidine; Drug Resistance, Neoplasm; Gemcitabine; Humans; Inhibitor of Apoptosis Proteins; Lung Neoplasms; Microtubule-Associated Proteins; Neoplasm Proteins; Nicotine; Paclitaxel; Promoter Regions, Genetic; Receptors, Nicotinic; Retinoblastoma Protein; Survivin; Up-Regulation; X-Linked Inhibitor of Apoptosis Protein | 2006 |
Nicotine induces cell proliferation by beta-arrestin-mediated activation of Src and Rb-Raf-1 pathways.
Topics: Arrestins; beta-Arrestins; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Cell Line, Tumor; Enzyme Activation; Humans; Lung Neoplasms; Nicotine; Promoter Regions, Genetic; Proto-Oncogene Proteins c-raf; Receptors, Nicotinic; Retinoblastoma Protein; src-Family Kinases | 2006 |
Suppression of cancer cell migration and invasion by protein phosphatase 2A through dephosphorylation of mu- and m-calpains.
Topics: Calpain; Cell Line, Tumor; Cell Movement; Ceramides; Gene Expression Regulation; Humans; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Transport; Up-Regulation | 2006 |
The consequences of the unregulated cigarette.
Topics: Humans; Lung Neoplasms; Nicotiana; Nicotine; Smoking; Tars; Tobacco Industry | 2006 |
Nicotine activates cell-signaling pathways through muscle-type and neuronal nicotinic acetylcholine receptors in non-small cell lung cancer cells.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; ErbB Receptors; Ganglionic Stimulants; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mitogen-Activated Protein Kinase 1; Nicotine; Nicotinic Agonists; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic; RNA, Messenger; Signal Transduction | 2007 |
Are lung cancers triggered by stopping smoking?
Topics: Adrenocorticotropic Hormone; Aged; Cell Division; Corticotropin-Releasing Hormone; Female; Humans; Lung Neoplasms; Male; Middle Aged; Models, Biological; Nicotine; Retrospective Studies; Smoking Cessation; Time Factors; Tobacco Use Disorder | 2007 |
[Misleading information on smoking in German medical textbooks].
Topics: Coronary Disease; Education, Medical; Germany; Humans; Lung Neoplasms; Nicotine; Risk Factors; Smoking; Textbooks as Topic; Tobacco Use Disorder | 2007 |
Lung cancer after quitting smoking: Is there a cause-effect relationship, or may some smokers decide to quit because they begin to feel ill from smoking-related pathologies?
Topics: Humans; Lung Neoplasms; Models, Biological; Nicotine; Smoking Cessation; Time Factors; Tobacco Use Disorder | 2007 |
Gender differences relative to smoking behavior and emissions of toxins from mainstream cigarette smoke.
Topics: Administration, Inhalation; Adult; Carcinogens, Environmental; Confidence Intervals; Dose-Response Relationship, Drug; Environmental Exposure; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Odds Ratio; Regression Analysis; Reproducibility of Results; Risk Assessment; Sex Factors; Smoking | 2007 |
The decline in lung cancer and the genetics of nicotine addiction.
Topics: Female; Global Health; Humans; Incidence; Lung Neoplasms; Male; Nicotine; Nicotinic Agonists; Smoking; Substance-Related Disorders; Survival Rate | 2007 |
Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers.
Topics: Adult; Aged; Aged, 80 and over; Bronchi; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Epithelial Cells; Female; Gene Expression; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Receptors, Nicotinic; RNA, Messenger; Smoking | 2007 |
Protein kinase Czeta abrogates the proapoptotic function of Bax through phosphorylation.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Cell Survival; Cytoplasm; Humans; Lung Neoplasms; Mice; Models, Biological; Mutation; Nicotine; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; RNA Interference | 2007 |
Nicotine stimulates human lung cancer cell growth by inducing fibronectin expression.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Antibodies; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Extracellular Signal-Regulated MAP Kinases; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha5beta1; Lung Neoplasms; Models, Biological; Nicotine; Peptides; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; Receptors, Nicotinic; RNA, Small Interfering; TOR Serine-Threonine Kinases | 2007 |
Nongenomic beta estrogen receptors enhance beta1 adrenergic signaling induced by the nicotine-derived carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human small airway epithelial cells.
Topics: Adenocarcinoma; Carcinogens; Epithelial Cells; Estrogen Receptor beta; Extracellular Signal-Regulated MAP Kinases; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Nicotine; Nitrosamines; Receptors, Adrenergic, beta-1; Smoking; Trachea | 2007 |
Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways.
Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Neoplasm Invasiveness; Nicotine; Phosphatidylinositol 3-Kinases; Receptors, Nicotinic; RNA, Small Interfering; Signal Transduction; Vascular Endothelial Growth Factor A | 2007 |
C. elegans as a model organism for in vivo screening in cancer: effects of human c-Met in lung cancer affect C. elegans vulva phenotypes.
Topics: Animals; Animals, Genetically Modified; Antineoplastic Agents; Caenorhabditis elegans; Drug Screening Assays, Antitumor; Female; Humans; Lung Neoplasms; Mutation; Nicotine; Phenotype; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; RNA Interference; Vulva | 2008 |
[Smoking and preventive medicine].
Topics: Cardiovascular Diseases; Female; Filtration; Humans; Lung Neoplasms; Male; Nicotine; Preventive Medicine; Risk; Smoking; Smoking Prevention; Tars | 1982 |
A case of oat cell carcinoma of the lung associated with ectopic production of ADH, neurophysin and ACTH.
Topics: ACTH Syndrome, Ectopic; Carcinoma, Small Cell; Estrogens; Female; Humans; Inappropriate ADH Syndrome; Lung Neoplasms; Middle Aged; Neurophysins; Nicotine; Paraneoplastic Endocrine Syndromes | 1980 |
Smoking. The physiologic effects.
Topics: Adult; Carboxyhemoglobin; Cardiovascular Diseases; Child; Female; Humans; Infant, Newborn; Lung Neoplasms; Male; Nicotine; Pregnancy; Respiratory Tract Diseases; Smoking; Tobacco Smoke Pollution; Tobacco Use Disorder | 1983 |
Amount of nicotine and carbon monoxide inhaled by smokers of low-tar, low-nicotine cigarettes.
Topics: Carbon Monoxide; Chromatography, Gas; Coronary Disease; Humans; Lung Diseases, Obstructive; Lung Neoplasms; Nicotine; Pulmonary Alveoli; Risk; Smoking; Tars | 1983 |
Investigation of the content and ratio of cotinine and nicotine-1'-N-oxide in the urine of smokers.
Topics: Adult; Aged; Cotinine; Cyclic N-Oxides; Female; Humans; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nicotine; Pyrrolidinones; Smoking | 1983 |
[Toxicology of tobacco smoke and smokers' diseases].
Topics: Arteriosclerosis; Carbon Monoxide; Coronary Disease; Disease; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Smoking; Tars | 1983 |
[Smoking and health (material for talks for World Health Day)].
Topics: Cardiovascular System; Environmental Exposure; Female; Global Health; Health; Humans; Lung Neoplasms; Male; Nicotine; Pregnancy; Smoking | 1980 |
Composition of tobaccos from countries with high and low incidences of lung cancer. I. Selenium, polonium-210, Alternaria, tar, and nicotine.
Topics: Alternaria; Colombia; Female; Humans; Lung Neoplasms; Male; Mexico; Mitosporic Fungi; Nicotiana; Nicotine; Plants, Toxic; Polonium; Selenium; Smoke; Sweden; Tars; United Kingdom; United States | 1981 |
Passive smoking.
Topics: Automobile Driving; Bronchitis; Carbon Monoxide; Dimethylnitrosamine; Female; Forced Expiratory Flow Rates; Humans; Hypersensitivity; Lung Neoplasms; Male; Nicotine; Physical Endurance; Pneumonia; Risk; Tobacco Smoke Pollution | 1982 |
[Smoking or health: the choice is yours (author's transl)].
Topics: Bronchitis; Carbon Monoxide; Carcinogens; Female; Heart Diseases; Humans; Irritants; Lung Diseases; Lung Neoplasms; Male; Nicotiana; Nicotine; Plants, Toxic; Pregnancy; Pregnancy Complications; Risk; Smoking | 1980 |
Comparative carcinogenicity and metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and N'-nitrosonornicotine in Syrian golden hamsters.
Topics: Animals; Carcinogens; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Cricetinae; Feces; Female; Injections, Subcutaneous; Lung Neoplasms; Male; Mesocricetus; Nasal Cavity; Neoplasms, Experimental; Nicotiana; Nicotine; Nitrosamines; Nose Neoplasms; Plants, Toxic; Pyridines | 1981 |
Mortality and type of cigarette smoked.
Topics: Coronary Disease; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoking; Tars | 1981 |
Comparative carcinogenicity in F344 rats of the tobacco-specific nitrosamines, N'-nitrosonornicotine and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Animals; Carcinogens; Female; Liver Neoplasms; Lung Neoplasms; Male; Nasal Cavity; Neoplasms, Experimental; Nicotiana; Nicotine; Nitrosamines; Nose Neoplasms; Plants, Toxic; Pyridines; Rats; Rats, Inbred F344 | 1980 |
Smoking and health: the role of the obstetrician and gynecologist.
Topics: Adolescent; Adult; Attitude of Health Personnel; Contraceptives, Oral, Synthetic; Female; Gynecology; Humans; Infant, Newborn; Lung Neoplasms; Male; Middle Aged; Nicotine; Obstetrics; Physician's Role; Pregnancy; Pregnancy Complications; Role; Smoking; Smoking Prevention; Substance-Related Disorders; Women | 1980 |
[Nicotine exposure and prevention of smoking in various European countries].
Topics: Adolescent; Adult; Coronary Disease; Europe; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Propaganda; Smoking Prevention | 1980 |
The low yield cigarette.
Topics: Carbon Monoxide; Humans; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoke; Smoking; Tars | 1980 |
Simultaneous exposure to nicotine and hyperoxia causes tumors in hamsters.
Topics: Adrenal Gland Neoplasms; Animals; Carcinogens; Cell Transformation, Neoplastic; Cricetinae; Hyperoxia; Hyperplasia; Lung Neoplasms; Male; Mesocricetus; Neuroendocrine Tumors; Nicotine; Nose Neoplasms; Phosphopyruvate Hydratase; Receptors, Nicotinic; Serotonin; Smoking | 1995 |
Urinary nicotine metabolite excretion and lung cancer risk in a female cohort.
Topics: Adult; Case-Control Studies; Cohort Studies; Creatinine; Female; Humans; Lung Neoplasms; Middle Aged; Nicotine; Risk Factors; Smoking | 1995 |
alpha-Bungarotoxin blocks the nicotinic receptor mediated increase in cell number in a neuroendocrine cell line.
Topics: Alkaloids; Azocines; Blotting, Northern; Bungarotoxins; Carcinoma, Small Cell; Cell Division; Humans; Iodine Radioisotopes; Lung Neoplasms; Neurosecretory Systems; Nicotine; Nicotinic Antagonists; Quinolizines; Receptors, Nicotinic; RNA, Messenger; Tubocurarine; Tumor Cells, Cultured | 1994 |
Opioids induce while nicotine suppresses apoptosis in human lung cancer cells.
Topics: Apoptosis; DNA Damage; DNA, Neoplasm; Drug Synergism; Hexamethonium; Humans; Lung Neoplasms; Methadone; Morphine; Nicotine; Receptors, Cholinergic; Sphingosine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1994 |
Nicotine stimulates a serotonergic autocrine loop in human small-cell lung carcinoma.
Topics: Carcinoma, Small Cell; Dose-Response Relationship, Drug; Humans; Lung Neoplasms; Mecamylamine; Nicotine; Serotonin | 1993 |
An enforceable indoor air quality standard for environmental tobacco smoke in the workplace.
Topics: Adult; Air Pollutants, Occupational; Air Pollution, Indoor; Cotinine; Environmental Monitoring; Humans; Lung Neoplasms; Models, Biological; Models, Theoretical; Nicotine; Occupational Exposure; Risk Factors; Tobacco Smoke Pollution; United States | 1993 |
Long-term effects of inhaled nicotine.
Topics: Administration, Inhalation; Animals; Arteriosclerosis; Cardiovascular System; Female; Fibroadenoma; Lung; Lung Neoplasms; Mammary Neoplasms, Experimental; Neoplasms, Experimental; Nicotine; Pituitary Neoplasms; Rats; Rats, Sprague-Dawley; Time Factors | 1996 |
alpha-Conotoxin imperialis I inhibits nicotine-evoked hormone release and cell proliferation in human neuroendocrine carcinoma cells.
Topics: Carcinoma, Small Cell; Cell Division; Conotoxins; Hormones; Humans; Lung Neoplasms; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oligopeptides; Receptors, Nicotinic; Tumor Cells, Cultured | 1996 |
Liggett comes clean.
Topics: Behavior, Addictive; Humans; Industry; Jurisprudence; Lung Neoplasms; Nicotine; Tobacco Use Disorder | 1996 |
Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.
Topics: Anticarcinogenic Agents; Biomarkers; Biotransformation; Carcinogens; Chromatography, High Pressure Liquid; Cotinine; Creatinine; Enzyme Inhibitors; Glucuronates; Humans; Inactivation, Metabolic; Isothiocyanates; Lung Neoplasms; Mass Spectrometry; Nicotine; Nitrosamines; Proteus mirabilis; Pyridines | 1997 |
Tobacco and cancer in Turkey.
Topics: Adolescent; Adult; Aged; Carbon Monoxide; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Plants, Toxic; Smoking; Tars; Turkey | 1996 |
Mechanisms of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells.
Topics: Autocrine Communication; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Lung Neoplasms; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pertussis Toxin; Protein-Tyrosine Kinases; Receptors, Cholinergic; Virulence Factors, Bordetella | 1997 |
Changes of smoking habits and beliefs during nurse training: a longitudinal study.
Topics: Adolescent; Adult; Asthma; Attitude to Health; Bronchitis; Cohort Studies; Coronary Artery Disease; Education, Nursing; Female; Health Behavior; Health Education; Health Knowledge, Attitudes, Practice; Health Promotion; Humans; Italy; Longitudinal Studies; Lung Neoplasms; Male; Middle Aged; Nicotine; Nurses; Personnel, Hospital; Prevalence; Prospective Studies; Recurrence; Smoking; Smoking Cessation; Students, Nursing; Substance-Related Disorders; Surveys and Questionnaires | 1997 |
Air nicotine and saliva cotinine as indicators of workplace passive smoking exposure and risk.
Topics: Air Pollutants, Occupational; Cotinine; Heart Diseases; Humans; Lung Neoplasms; Models, Biological; Monte Carlo Method; Nicotine; Occupational Diseases; Occupational Exposure; Risk Assessment; Saliva; Tobacco Smoke Pollution; United States | 1998 |
Nerve growth factor abrogates the tumorigenicity of human small cell lung cancer cell lines.
Topics: Animals; Carcinoma, Small Cell; Cell Division; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasms, Experimental; Nerve Growth Factors; Nicotine; Receptors, Nerve Growth Factor; Tumor Cells, Cultured | 1998 |
Signalling pathways involved in nicotine regulation of apoptosis of human lung cancer cells.
Topics: Apoptosis; Enzyme Activation; Enzyme Inhibitors; Humans; Lung Neoplasms; Methadone; Mitogen-Activated Protein Kinase 1; Nicotine; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tumor Cells, Cultured | 1998 |
Downregulation of nicotinic acetylcholine receptors by nerve growth factor in human small cell lung carcinoma cell lines.
Topics: Carcinoma, Small Cell; Cell Division; Down-Regulation; Humans; Lung Neoplasms; Nerve Growth Factors; Nicotine; Receptors, Nicotinic; Serotonin; Thymidine; Tumor Cells, Cultured | 1998 |
Quantitation of urinary metabolites of a tobacco-specific lung carcinogen after smoking cessation.
Topics: Adult; Animals; Carcinogens; Cotinine; Female; Glucuronates; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Nitrosamines; Rats; Rats, Inbred F344; Smoking Cessation | 1999 |
Genetic variation of CYP2A6, smoking, and risk of cancer.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Case-Control Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Genotype; Humans; Los Angeles; Lung Neoplasms; Mixed Function Oxygenases; Nicotine; Risk Factors; Smoking | 1999 |
CYP2A6 polymorphism, nicotine, and environmental nitrosamines.
Topics: Alleles; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Humans; Lung Neoplasms; Mixed Function Oxygenases; Nicotine; Nitrosamines; Polymorphism, Genetic; Smoking | 1999 |
[The causes of increased risk for lung cancer in the pulp and paper industry workers. The effect of smoking and exposure to chemicals].
Topics: Adult; Cellulose; Chemical Industry; Cohort Studies; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Occupational Diseases; Occupational Exposure; Paper; Poland; Retrospective Studies; Risk Factors; Smoking | 1999 |
Sex-specific expression of gastrin-releasing peptide receptor: relationship to smoking history and risk of lung cancer.
Topics: Adult; Aged; Cells, Cultured; Female; Fibroblasts; Gene Expression Regulation, Neoplastic; Genotype; Humans; Lung; Lung Neoplasms; Male; Middle Aged; Nicotine; Polymorphism, Genetic; Receptors, Bombesin; Respiratory System; Reverse Transcriptase Polymerase Chain Reaction; Risk; RNA Probes; RNA, Messenger; RNA, Neoplasm; Sex Factors; Smoking | 2000 |
It's time for a change: cigarette smokers deserve meaningful information about their cigarettes.
Topics: Administration, Inhalation; Advertising; Dose-Response Relationship, Drug; Health Education; Humans; Lung Neoplasms; Nicotine; Smoking; Tars; Tobacco Industry; United States; United States Federal Trade Commission; United States Food and Drug Administration | 2000 |
Doses of nicotine and lung carcinogens delivered to cigarette smokers.
Topics: Administration, Inhalation; Adult; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Smoking; Tars; United States; United States Federal Trade Commission | 2000 |
Activation of voltage-operated Ca2+-channels in human small cell lung carcinoma by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.
Topics: Calcium Channels; Carcinogens; Carcinoma, Small Cell; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Tumor Cells, Cultured | 2000 |
"Women and smoking towards the millennium".
Topics: Autoimmune Diseases; Autoimmunity; Breast Neoplasms; Cell Transformation, Neoplastic; Female; Herpesviridae Infections; Humans; Lung Neoplasms; Mosaicism; Nicotine; Nicotinic Agonists; Pregnancy; Pregnancy Complications; Skin Aging; Smoking; Smoking Cessation; Women's Health | 1999 |
Nicotine effects on proliferation and the bombesin-like peptide autocrine system in human small cell lung carcinoma SHP77 cells in culture.
Topics: Binding, Competitive; Bombesin; Carcinoma, Small Cell; Cell Division; Cell Line; Enzyme-Linked Immunosorbent Assay; Humans; Lung Neoplasms; Nicotine; Peptides; Polymerase Chain Reaction; Receptors, Bombesin; RNA, Messenger; Tumor Cells, Cultured | 2000 |
Metabolites of a tobacco-specific lung carcinogen in nonsmoking women exposed to environmental tobacco smoke.
Topics: Adult; Aged; Carcinogens; Cotinine; Creatinine; Female; Glucuronates; Humans; Lung Neoplasms; Middle Aged; Nicotine; Nitrosamines; Risk; Risk Factors; Smoking; Surveys and Questionnaires; Tobacco Smoke Pollution | 2001 |
[Alkaloids in Sophora alopecuroides seed and relevant tests for activity].
Topics: Alkaloids; Anti-Bacterial Agents; Anti-Infective Agents; Antineoplastic Agents, Phytogenic; Cystine; Drugs, Chinese Herbal; Fabaceae; Lung Neoplasms; Matrines; Nicotine; Plants, Medicinal; Quinolizines; Seeds; Tumor Cells, Cultured | 1997 |
They have given us the ammunition--we should use it.
Topics: Adult; Child; Developing Countries; Female; Health Knowledge, Attitudes, Practice; Humans; Incidence; Liability, Legal; Lung Neoplasms; Male; Nicotine; Risk Assessment; Smoking; Social Responsibility; Tobacco Industry; World Health Organization | 2001 |
[Tobacco addiction. Epidemiology and pathology associated with tobacco].
Topics: Adolescent; Adult; Aged; Female; France; Ganglionic Stimulants; Health Status; Humans; Incidence; Lung Neoplasms; Male; Middle Aged; Mouth Neoplasms; Nicotine; Public Health; Smoking; Smoking Cessation; Tobacco Smoke Pollution; Tobacco Use Disorder | 2001 |
Nicotine stimulates angiogenesis and promotes tumor growth and atherosclerosis.
Topics: Animals; Arteriosclerosis; Carcinoma, Lewis Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Nicotine | 2001 |
[Molecular basis of carcinogenesis in lung cancer induced by cigarette smoking].
Topics: Cytochrome P-450 CYP1A1; DNA Adducts; Glutathione Transferase; Humans; Lung Neoplasms; Lymphocytes; Nicotine; Point Mutation; RNA, Messenger; Smoking | 2001 |
Health impact of "reduced yield" cigarettes: a critical assessment of the epidemiological evidence.
Topics: Case-Control Studies; Cohort Studies; Consumer Product Safety; Humans; Lung Neoplasms; Nicotiana; Nicotine; Risk Assessment; Smoke; Smoking; Tars | 2001 |
Slower metabolism and reduced intake of nicotine from cigarette smoking in Chinese-Americans.
Topics: Adult; Asian; Cotinine; Female; Hispanic or Latino; Humans; Lung Neoplasms; Male; Nicotine; Smoking; Smoking Cessation; White People | 2002 |
Gender-dependent expression of alpha and beta estrogen receptors in human nontumor and tumor lung tissue.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Blotting, Western; Carcinoma, Adenosquamous; Carcinoma, Squamous Cell; DNA Primers; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Exons; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Receptors, Estrogen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sex Factors | 2002 |
Nicotine modulates the effects of retinoids on growth inhibition and RAR beta expression in lung cancer cells.
Topics: Benzoates; Blotting, Northern; Cell Division; COUP Transcription Factors; DNA-Binding Proteins; Drug Interactions; Gene Expression; Humans; Lung Neoplasms; Nicotine; Nuclear Receptor Subfamily 4, Group A, Member 1; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Retinoids; Transcription Factors; Transfection; Tretinoin; Tumor Cells, Cultured | 2002 |
Chemical studies on tobacco smoke. XLII. Nitrosonornicotine: presence in tobacco, formation and carcinogenicity.
Topics: Animals; Cricetinae; Esophageal Neoplasms; Female; Hydrogen-Ion Concentration; Laryngeal Neoplasms; Lung Neoplasms; Mice; Neoplasms; Neoplasms, Experimental; Nicotiana; Nicotine; Nitrosamines; Nose Neoplasms; Pharyngeal Neoplasms; Plants, Toxic; Rats; Skin Neoplasms; Smoking; Tobacco, Smokeless | 1976 |
Buffering capacity of the smoke of different tobaccos in relation to lung cancer risks.
Topics: Buffers; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Risk; Smoking; United Kingdom; United States | 1976 |
Mortality from lung cancer and coronary heart-disease in relation to changes in smoking habits.
Topics: Adult; Carbon Monoxide; Coronary Disease; England; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Sex Ratio; Smoking; Tars; Wales | 1976 |
Asbestos and smoking.
Topics: Asbestos; Drug Synergism; Environmental Exposure; Humans; Lung Neoplasms; Nicotine; Pulmonary Fibrosis; Risk; Smoking | 1979 |
[Harmful effects of tobacco smoke on the respiratory system].
Topics: Bronchitis; Humans; Lung Diseases; Lung Neoplasms; Nicotine; Respiratory System; Smoking | 1979 |
Tobacco-specific nitrosamines: formation from nicotine in vitro and during tobacco curing and carcinogenicity in strain A mice.
Topics: Adenoma; Animals; Female; In Vitro Techniques; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasms, Experimental; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Pyridines | 1978 |
Low-risk cigarettes: a prescription.
Topics: Carboxyhemoglobin; Humans; Lung Diseases; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoking | 1976 |
"Tar" and nicotine content of cigarette smoke in relation to death rates.
Topics: Coronary Disease; Female; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Prospective Studies; Smoking; Tars; United States | 1976 |
Binding of (3H)benzo(a)pyrene to DNA in cultured human bronchus.
Topics: Benzopyrenes; Bronchi; Butylated Hydroxytoluene; Culture Techniques; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Fibroblasts; Flavonoids; Humans; Lung Neoplasms; Nicotine; Temperature; Time Factors | 1976 |
Evaluation of beeswax-tricaprylin vehicle for pulmonary carcinogenesis studies.
Topics: Animals; Caprylates; Drug Implants; Lung; Lung Neoplasms; Methylcholanthrene; Nicotine; Pharmaceutical Vehicles; Phenols; Polycyclic Compounds; Rats; Time Factors; Triglycerides; Waxes | 1976 |
Health effects of smoking: current concepts.
Topics: Environmental Exposure; Health; Humans; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoke; Smoking; Tars; Terminology as Topic | 1992 |
Skin patches to prevent lung cancer.
Topics: Administration, Cutaneous; Humans; Lung Neoplasms; Nicotine; Smoking Prevention | 1991 |
Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cell Division; Cell Line; Cell Membrane; Humans; Kinetics; Lung Neoplasms; Morphine; Nicotine; Receptors, Nicotinic; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tumor Cells, Cultured | 1990 |
"Tar", nicotine, and carbon monoxide content of Thai cigarettes, and implications for cancer prevention in Thailand.
Topics: Carbon Monoxide; Female; Humans; Incidence; Lung Neoplasms; Male; Mouth Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoking; Tars; Thailand | 1990 |
[Epidemiology of lung cancer with special reference to cigarette smoking].
Topics: Age Factors; Female; Humans; Japan; Lung Neoplasms; Male; Nicotine; Risk; Smoking; Tobacco Smoke Pollution | 1990 |
Cell type specific, receptor-mediated modulation of growth kinetics in human lung cancer cell lines by nicotine and tobacco-related nitrosamines.
Topics: Adenocarcinoma; Carcinogens; Cell Division; Diethylnitrosamine; Hexamethonium; Hexamethonium Compounds; Humans; Lung Neoplasms; Nicotine; Nitrosamines; Receptors, Nicotinic; Tumor Cells, Cultured | 1989 |
Low-tar cigarettes: bane or benefit.
Topics: Advertising; Carbon Monoxide; Developing Countries; Female; Humans; Industry; Lung Neoplasms; Male; Mouth Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Risk; Sex Factors; Smoking; Tars | 1987 |
The role of the physician in changing patients' smoking behavior: results of a survey of physicians.
Topics: Adult; Attitude of Health Personnel; Chewing Gum; Combined Modality Therapy; Humans; Lung Neoplasms; Middle Aged; Nicotine; Patient Education as Topic; Physician-Patient Relations; Smoking Prevention | 1986 |
[The smoking problem].
Topics: Cardiovascular Diseases; Female; Humans; Japan; Lung Neoplasms; Male; Nicotine; Pregnancy; Reproduction; Risk; Smoking; Smoking Prevention; Substance-Related Disorders; Tobacco Smoke Pollution; United Kingdom; United States | 1986 |
The "less hazardous" cigarette: a deadly delusion.
Topics: Adult; Carbon Monoxide; Female; Humans; Lung Neoplasms; Male; Nicotine; Risk; Smoking; Tars; Tobacco Use Disorder | 1985 |
Nicotine: a precursor for carcinogens.
Topics: Animals; Biotransformation; Carcinogens; Cotinine; Humans; Lung Neoplasms; Nicotiana; Nicotine; Nitrosamines; Plants, Toxic; Rats; Smoking | 1985 |
Cardiovascular and other diseases in smokers of low yield cigarettes.
Topics: Adult; Bronchial Neoplasms; California; Cardiovascular Diseases; Female; Hospitalization; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Peptic Ulcer; Plants, Toxic; Prospective Studies; Risk; Smoking; Tars; Tracheal Neoplasms | 1985 |
Combined effect of asbestos exposure and smoking on mortality from lung cancer in factory workers.
Topics: Asbestos; Asbestosis; Carcinoma, Bronchogenic; Drug Synergism; Environmental Exposure; Female; Humans; Lung Neoplasms; Male; Mesothelioma; Nicotine; Occupational Diseases; Sex Factors; Smoking | 1972 |
Smoking, cancer, and coronary heart-disease.
Topics: Blood Platelets; Carcinoma, Bronchogenic; Cell Membrane; Coronary Disease; Cysteine; Free Radicals; Humans; Lung Neoplasms; Nicotine; Radiation-Protective Agents; Smoking; Thrombosis | 1973 |
Flue-cured and air-cured tobacco.
Topics: Carbohydrates; Humans; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Tars | 1973 |
[Round-table conference on harmful effects of smoking. A synopsis of a round-table conference held during the XXVth Congress of the Polish Society for Internal Medicine (Katowice, 20-22 September, 1973)].
Topics: Animals; Cats; Congresses as Topic; Female; Heart; Histamine Release; Humans; Lung Neoplasms; Male; Nicotine; Peptic Ulcer; Poland; Smoking; Societies, Medical | 1974 |
[Physicians: smoking is prohibited. Data on the dangers and correlation between cigarettes and cardiorespiratory diseases].
Topics: Animals; Benzopyrenes; Carbon Monoxide Poisoning; Carcinogens; Cilia; Heart Diseases; Humans; Lung Neoplasms; Nicotine; Smoking | 1972 |
The sugar content and the pH of the smoke of cigarette, cigar and pipe tobaccos in relation to lung cancer.
Topics: Carbohydrates; Filtration; Humans; Hydrogen-Ion Concentration; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoke; Smoking | 1972 |
Risk of lung cancer according to histologic type and cigarette dosage.
Topics: Adenocarcinoma; Aged; Carcinoma; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Prospective Studies; Smoking; Surveys and Questionnaires; World Health Organization | 1972 |
[Tobacco smoking and lung cancer].
Topics: Animals; Dogs; Female; Humans; Lung Neoplasms; Male; Nicotiana; Nicotine; Plants, Toxic; Smoking; Smoking Prevention | 1973 |
Letter: Lung cancer and smoking.
Topics: Humans; Lung Neoplasms; Nicotine; Smoking | 1973 |
Review of current research in Germany on less harmful ways of smoking.
Topics: Animals; Carcinogens; Germany; Lung Neoplasms; Mice; Nicotiana; Nicotine; Plants, Toxic; Rats; Research; Smoke; Smoking | 1972 |
Less harmful ways of smoking.
Topics: Adult; Aged; Bronchitis; Cardiovascular Diseases; Chronic Disease; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Plants, Toxic; Pulmonary Emphysema; Smoke; Smoking; Smoking Prevention | 1972 |
Tumor promoters in tobacco and cigarette-smoke condensate.
Topics: Animals; Benz(a)Anthracenes; Carcinogens; Lung Neoplasms; Mice; Molecular Weight; Nicotiana; Nicotine; Plants, Toxic; Smoke; Smoking | 1972 |
Sugar content of the tobacco and pH of the smoke in relation to lung cancer risks of cigarette smoking.
Topics: Animals; Carbohydrates; Filtration; Hydrogen-Ion Concentration; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Rats; Smoke; Smoking | 1972 |
Plasma arginine vasopressin in the syndrome of inappropriate antidiuretic hormone secretion.
Topics: Carcinoma, Bronchogenic; Craniocerebral Trauma; Diuresis; Drinking; Extracellular Space; Humans; Hypertonic Solutions; Hyponatremia; Lung Neoplasms; Methods; Nicotine; Osmolar Concentration; Pituitary Function Tests; Porphyrias; Sodium Chloride; Vasopressins | 1972 |
Canadian studies aimed toward a less harmful cigarette.
Topics: Canada; Female; Free Radicals; Humans; Lung Neoplasms; Male; Metals; Middle Aged; Nicotiana; Nicotine; Plants, Toxic; Pregnancy; Research; Smoke; Smoking; Statistics as Topic; Twins | 1972 |
Does the smoking of filter cigarettes reduce the incidence of tobacco-related disease as compared with the smoking of non-filter cigarettes?
Topics: Filtration; Humans; Lung Neoplasms; Nicotiana; Nicotine; Plants, Toxic; Smoking; Tars | 1972 |
How smoking causes lung cancer.
Topics: Humans; Lung Neoplasms; Mucous Membrane; Nicotine; Smoking; Vasoconstrictor Agents | 1971 |
[Problems of "passive smoking". Opinion on H.P. Harke, Münch. med. Wschr. 112 (1970) 51, 2328-2334].
Topics: Air Pollution; Animals; Conjunctivitis; Cough; Cricetinae; Germany, West; Headache; Health Planning; Housing; Humans; Hypersensitivity; Legislation, Medical; Lung Neoplasms; Nicotine; Public Health; Respiration; Smoke; Smoking; Vertigo | 1971 |
["Problems of passive smoking". Final comments on V. Schmidt, H. Hess, F. Portheine, Münch. med. Wschr. 113 (1970) 18, 702-709].
Topics: Air Pollution; Animals; Cricetinae; Humans; Lung Neoplasms; Nicotiana; Nicotine; Occupational Medicine; Plants, Toxic; Public Relations; Smoke; Smoking | 1971 |
Contribution to the investigation of the effect of cigarette smoking.
Topics: Arteriosclerosis; Autopsy; Czechoslovakia; Female; Humans; Lung Neoplasms; Male; Myocardial Infarction; Nicotine; Peptic Ulcer; Smoking | 1971 |
Smoking disease: a self-inflicted injury.
Topics: Attitude; Cardiovascular Diseases; Health Education; Humans; Lung Neoplasms; Nicotine; Public Opinion; Respiratory Tract Diseases; Smoking Prevention | 1970 |
The epidemiology of lung cancer. Recent trends.
Topics: Adenocarcinoma; Age Factors; Aged; Carcinoma, Squamous Cell; Female; Filtration; Hospitals, Special; Humans; Lung Neoplasms; Male; Middle Aged; Nicotine; Religion; Retrospective Studies; Sex Factors; Smoking; Smoking Prevention; Tars; United States | 1970 |
[Relation between the smoking habit and lung cancer].
Topics: Adult; Humans; Lung Neoplasms; Male; Middle Aged; Nicotiana; Nicotine; Plants, Toxic; Smoking | 1970 |
[Further contributions on the principle of inverse association].
Topics: Carcinogens; Cholelithiasis; Czechoslovakia; Female; Gallbladder Neoplasms; Humans; Indians, North American; Liver Cirrhosis; Liver Neoplasms; Lung Neoplasms; Male; Mining; Newfoundland and Labrador; Nicotine; Occupations; Radon; United States | 1968 |