nicotine has been researched along with Benign Frontal Childhood Epilepsy in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (58.82) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Absalom, NL; Ahring, PK; Balle, T; Chebib, M; Indurthi, DC; Lewis, TM; Liao, VW; Qudah, T | 1 |
| Aroni, S; Carta, G; De Montis, MG; Lecca, S; Marrosu, F; Melis, M; Muntoni, AL; Murru, E; Pillolla, G; Pistis, M; Puligheddu, M; Scheggi, S | 1 |
| Kaakkola, S; Tuominen, R | 1 |
| Douglass, LM; Pavlakis, PP | 1 |
| Hirose, S; Kaneko, S; Migita, K; Mori, F; Nikaido, Y; Okada, M; Shiba, Y; Ueno, S; Wakabayashi, K; Yamada, J | 1 |
| Fukuma, G; Hase, K; Hirose, S; Kaneko, S; Kijima, H; Kishi, A; Kojima, T; Mitsudome, A; Miura, Y; Mori, F; Ohno, H; Okada, M; Saito, R; Sato, A; Takahara, T; Takano, Y; Tomiyama, M; Ueno, S; Wakabayashi, K; Yoshida, S; Zhu, G | 1 |
| Cohen, BN; Lester, HA; Moss, FJ; Son, CD | 1 |
| Banghart, MR; Dougherty, DA; Goate, AM; Lester, HA; Miwa, J; Pantoja, R; Son, CD; Srinivasan, R; Wang, JC; Xiao, C | 1 |
| Ambrosi, P; Becchetti, A; Curia, G; Di Resta, C | 1 |
| Blumkin, L; Kivity, S; Lerman-Sagie, T; Leshinsky-Silver, E; Lev, D; Nishri, D; Yosef, Y; Zerem, A | 1 |
| Eaton, V; Pope, KJ; Willoughby, JO | 1 |
| Bertrand, D; Hogg, RC | 1 |
| Cooper, J; Kuryatov, A; Lindstrom, J; Luo, J | 1 |
| Brodtkorb, E; Picard, F | 1 |
| Boulter, J; Glykys, J; Klaassen, A; Labarca, C; Maguire, J; Mody, I | 1 |
| Steinlein, OK | 1 |
| Berkovic, SF; Cahir, E; Chen, F; Cohen, BN; Davies, PJ; Drago, J; Fonck, C; Gantois, I; Grady, SR; Horne, MK; Labarca, C; Lawrence, A; Lester, HA; Marks, MJ; McClure-Begley, T; McIntosh, JM; Murphy, M; Petrou, S; Teper, Y; Waddington, J; Whyte, D | 1 |
4 review(s) available for nicotine and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
[Nicotine and neurologic diseases--even a noxious substance may possess beneficial properties].
Topics: Alzheimer Disease; Ataxia; Benzazepines; Cognitive Dysfunction; Epilepsy, Frontal Lobe; Humans; Mutation; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinoxalines; Receptors, Nicotinic; Tobacco Use Cessation Devices; Varenicline | 2013 |
Nicotine is a selective pharmacological chaperone of acetylcholine receptor number and stoichiometry. Implications for drug discovery.
Topics: Acetylcholine; Animals; Drug Discovery; Endoplasmic Reticulum; Epilepsy, Frontal Lobe; Hippocampus; Mice; Models, Biological; Muscle Proteins; Mutation, Missense; Nerve Tissue Proteins; Neurotransmitter Agents; Nicotine; Parkinson Disease; Receptors, Nicotinic; Smoking; Tobacco Use Disorder; Up-Regulation; Ventral Tegmental Area | 2009 |
Neuronal nicotinic receptors and epilepsy, from genes to possible therapeutic compounds.
Topics: Animals; Carbamazepine; Epilepsy, Frontal Lobe; Gene Expression; Humans; Ligands; Models, Biological; Mutation; Neurons; Nicotine; Receptors, Nicotinic | 2004 |
Human disorders caused by the disruption of the regulation of excitatory neurotransmission.
Topics: Amino Acid Sequence; Angelman Syndrome; Epilepsy, Frontal Lobe; Excitatory Postsynaptic Potentials; Humans; Migraine Disorders; Molecular Sequence Data; Mutation; Myasthenic Syndromes, Congenital; Nicotine; Potassium Channels, Voltage-Gated; Receptors, Nicotinic; Rett Syndrome; Sodium Channels; Spinocerebellar Ataxias; Synaptic Transmission | 2008 |
1 trial(s) available for nicotine and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
Nicotine as an antiepileptic agent in ADNFLE: an N-of-one study.
Topics: Administration, Cutaneous; Adult; Anticonvulsants; Double-Blind Method; Epilepsy, Frontal Lobe; Female; Humans; Mutation; Nicotine | 2003 |
12 other study(ies) available for nicotine and Benign Frontal Childhood Epilepsy
| Article | Year |
|---|---|
Revisiting autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) mutations in the nicotinic acetylcholine receptor reveal an increase in efficacy regardless of stochiometry.
Topics: Acetylcholine; Alkaloids; Animals; Azocines; Epilepsy, Frontal Lobe; Female; Mutation; Nicotine; Nicotinic Agonists; Oocytes; Quinolizines; Receptors, Nicotinic; Varenicline; Xenopus laevis | 2019 |
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Epilepsy, Frontal Lobe; Fenofibrate; Frontal Lobe; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Nicotine; Patch-Clamp Techniques; Phosphorylation; PPAR alpha; Pyramidal Cells; Pyrimidines; Rats; Receptors, Nicotinic; Seizures | 2013 |
Pearls & Oysters: A case of refractory nocturnal seizures: Putting out fires without smoke.
Topics: Adult; Epilepsy, Frontal Lobe; Female; Humans; Nicotine; Nicotinic Agonists; Tobacco Use Cessation Devices | 2015 |
Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the β2-subunit of the nicotinic acetylcholine receptor.
Topics: Animals; Brain; Disease Models, Animal; Electroencephalography; Epilepsy; Epilepsy, Frontal Lobe; Male; Mutation, Missense; Nicotine; Protein Subunits; Rats; Rats, Transgenic; Receptors, Nicotinic; Sensorimotor Cortex | 2015 |
Rats harboring S284L Chrna4 mutation show attenuation of synaptic and extrasynaptic GABAergic transmission and exhibit the nocturnal frontal lobe epilepsy phenotype.
Topics: Age Factors; Analysis of Variance; Animals; Behavior, Animal; Cerebral Cortex; Dose-Response Relationship, Drug; Electroencephalography; Epilepsy, Frontal Lobe; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Hot Temperature; In Vitro Techniques; Leucine; Microscopy, Immunoelectron; Motor Activity; Motor Skills; Mutation; Neurotransmitter Agents; Nicotine; Pain Measurement; Pentylenetetrazole; Phenotype; Rats; Rats, Transgenic; Receptors, Nicotinic; Serine; Synaptic Transmission | 2008 |
Nicotine normalizes intracellular subunit stoichiometry of nicotinic receptors carrying mutations linked to autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Cells, Cultured; Epilepsy, Frontal Lobe; Fluorescence Resonance Energy Transfer; Humans; Mutation; Nicotine; Photobleaching; Protein Subunits; Receptors, Nicotinic | 2009 |
Effect of carbamazepine and oxcarbazepine on wild-type and mutant neuronal nicotinic acetylcholine receptors linked to nocturnal frontal lobe epilepsy.
Topics: Action Potentials; Anticonvulsants; Carbamazepine; Cell Line; Epilepsy, Frontal Lobe; Humans; Molecular Structure; Mutation; Nicotine; Patch-Clamp Techniques; Protein Binding; Protein Subunits; Receptors, Nicotinic; Transfection | 2010 |
Resolution of epileptic encephalopathy following treatment with transdermal nicotine.
Topics: Adolescent; Electroencephalography; Epilepsy, Frontal Lobe; Female; Humans; Nicotine; Tobacco Use Cessation Devices; Treatment Outcome | 2013 |
Nicotine acts as a pharmacological chaperone to up-regulate human alpha4beta2 acetylcholine receptors.
Topics: Cell Line; Cross-Linking Reagents; Dimerization; Epilepsy, Frontal Lobe; Humans; Molecular Chaperones; Mutation; Nicotine; Octoxynol; Protein Subunits; Receptors, Nicotinic; Transfection; Up-Regulation | 2005 |
Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Administration, Cutaneous; Adult; Aged; Anticonvulsants; Epilepsy, Frontal Lobe; Female; Humans; Male; Middle Aged; Mutation; Nicotine; Receptors, Nicotinic; Seizures; Sleep; Smoking | 2006 |
Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Frontal Lobe; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Mice, Transgenic; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Seizures | 2006 |
Nicotine-induced dystonic arousal complex in a mouse line harboring a human autosomal-dominant nocturnal frontal lobe epilepsy mutation.
Topics: Animals; Arousal; Disease Models, Animal; Dystonic Disorders; Epilepsy, Frontal Lobe; Female; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Neurologic Mutants; Mice, Transgenic; Mutation; Nicotine; Rats; Species Specificity; Xenopus | 2007 |