nicotine has been researched along with Absence Seizure in 163 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 79 (48.47) | 18.7374 |
1990's | 20 (12.27) | 18.2507 |
2000's | 35 (21.47) | 29.6817 |
2010's | 21 (12.88) | 24.3611 |
2020's | 8 (4.91) | 2.80 |
Authors | Studies |
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Amadeo, A; Becchetti, A; Coatti, A; Colombo, G; Madaschi, L; Meneghini, S; Milani, N; Modena, D | 1 |
Funaro, MC; Khan, W; Moeller, JJ; Narrett, JA | 1 |
Benowitz, NL | 1 |
Faulcon, LM; Limpert, J; Murphy, I; Rudy, S; Wang, B | 1 |
Carson, RP; Kozek, LK; Wharton, JD | 1 |
Fang, ZT; Shao, XM | 1 |
Beno, S; Gilley, M | 1 |
Baker, DL; Deats, S; DeMichele, G; Dymond, R; O'Brien, M; Pagán, OR | 1 |
Cyranoski, D | 1 |
Chellian, R; Pandy, V | 1 |
Zolot, J | 1 |
Aroni, S; Carta, G; De Montis, MG; Lecca, S; Marrosu, F; Melis, M; Muntoni, AL; Murru, E; Pillolla, G; Pistis, M; Puligheddu, M; Scheggi, S | 1 |
Do, SH; Hur, W; Lim, YJ; Yoon, HJ; Zuo, Z | 1 |
Bach, D; Baker, D; Deats, S; Montgomery, E; Pagán, OR | 1 |
Fritz, K; Holoyda, B; Xiong, GL | 1 |
Berg, DK; Cao, SX; Chen, XJ; Chen, Z; Duan, S; He, HY; Li, XM; Shen, CJ; Sun, P; Wang, XD; Yang, CH; Zhang, Y | 1 |
Bao, J; Han, X; Li, X; Liu, H; Liu, Y; Thakur, M; Ye, A | 1 |
Bespalov, AY; Dravolina, OA; Dumpis, MA; Litasova, EV; Nikolaev, DN; Piotrovskiy, LB; Yakovleva, EE | 1 |
Chakrabarti, A; Medhi, B; Sahai, AK; Sood, N | 1 |
Efremov, OM; Gmiro, VE; Serdyuk, SE | 1 |
Funakoshi, T; Kobayashi, S; Ohashi, S; Tanaka, T | 1 |
Rehni, AK; Singh, TG | 1 |
Maresova, D; Pokorny, J; Riljak, V | 1 |
Desaer, C; Ramakrishnan, L | 1 |
Chakrabarti, A; Hota, D; Sahai, AK; Sood, N | 1 |
Benavidez, JM; Blednov, YA; Harris, RA; Homanics, GE | 1 |
Amador-Arjona, A; Armengol, L; Cabrera, R; Dierssen, M; Estivill, X; Fernández-Montes, RD; Gallego, X; Gratacòs, M; Maldonado, R; Marks, MJ; Molas, S; Murtra, P; Pumarola, M; Robles, N; Sabrià, J | 1 |
Ahamehe, M; Arzi, A; Sarahroodi, S | 1 |
Bach, D; Baker, D; Deats, S; Kotturu, D; Montgomery, E; Pagán, OR; Raffa, RB; Randolph, C; Rawls, S; Tallarida, C; Tenaglia, M; Wilk, G | 1 |
Gholami, M; Hajizadeh-Moghaddam, A; Roshan-Milani, S; Saboory, E; Zare, S | 1 |
Cohen, BN; Fonck, C; Grady, SR; Laverty, DC; Lester, HA; Lindstrom, JM; Marks, MJ; McIntosh, JM; McKinney, S; O'Neill, HC; Patzlaff, NE | 1 |
Aubin, HJ | 1 |
Finn, DA; Mark, GP | 1 |
Danysz, W; Löscher, W; Parsons, CG; Potschka, H; Wlaź, P | 1 |
Collins, AC; Damaj, MI; Deshpande, P; Fonck, C; Labarca, C; Lester, HA; Marks, MJ; Nashmi, R; Riedel, A; Schwarz, J | 1 |
Beaudet, A; Broide, RS; De Biasi, M; Orr-Urtreger, A; Paylor, R; Salas, R | 1 |
Bontempi, B; Lloyd, GK; Menzaghi, F; Risbrough, VB; Whelan, KT | 1 |
BOVET, D; LONGO, VG | 1 |
LAURENCE, DR; STACEY, RS | 2 |
GOKHALE, SD; GULATI, OD | 1 |
MICHAELSON, SM; ORCUTT, JA; PRYTHERCH, JP | 1 |
YAMAMOTO, I | 1 |
NAGAI, K | 1 |
VARDAPETIAN, GA | 1 |
ILIUCHENOK, RIu; OSTROVSKAIA, RU; VINNITSKII, IM | 1 |
CHUBB, FL; HAJDU, A; KOMLOSSY, J; LEE, CF; MCCOLL, JD | 1 |
FUJIWARA, M; SHIMAMOTO, K; YAMAWAKI, T | 1 |
ZEIMAL, EV | 2 |
OTORI, K | 1 |
Balogh, S; Collins, AC; Damaj, MI; Fonck, C; Labarca, C; Lester, HA; McKinney, S; Owens, J; Tapper, AR; Wehner, JM | 1 |
Beaudet, AL; Kedmi, M; Orr-Urtreger, A | 1 |
Bahçekapili, N; Diler, AS; Uzüm, G; Ziylan, YZ | 1 |
Bassetto, L; Cook, KD; De Biasi, M; Salas, R | 1 |
Bastlund, JF; Berry, D; Watson, WP | 1 |
Martin-Garcia, E; Pallares, M | 1 |
Brodtkorb, E; Picard, F | 1 |
Abraham, P; Damaj, MI; Ivy Carroll, F; Ma, W; Martin, BR; Navarro, HA; Wolckenhauer, SA | 1 |
Boulter, J; Glykys, J; Klaassen, A; Labarca, C; Maguire, J; Mody, I | 1 |
Bing, G; Chae, JS; Cheon, MA; Jung, ME; Kim, HC; Kim, WK; Ko, KH; Nah, SY; Shin, EJ; Wie, MB | 1 |
Crouch, EL; Iacob, E; Jenkins, PM; Lautner, MA; Mexal, S; Stitzel, JA | 1 |
Kedmi, M; Orr-Urtreger, A | 1 |
Belluzzi, JD; Gee, KW; Hogenkamp, DJ; Leslie, FM; Li, WY; Tran, MB; Whittemore, ER; Yoshimura, RF | 1 |
Chan, MH; Chen, HH; Chien, TH; Tang, YC | 1 |
Levin, ED; Timofeeva, OA | 1 |
Chow, SC; Johnston, GA; Skerritt, JH | 1 |
Iizuka, H; Kawaguchi, T; Shimada, A; Yanagita, T | 1 |
Collins, AC; Marks, MJ; Miner, LL | 4 |
Chaturvedi, AK | 1 |
Caulfield, MP; Higgins, GA | 1 |
Bonnaud, B; Charveron, M; Cousse, H; Lauressergues, H; Morre, M; Mouzin, G; Stenger, A | 1 |
Brioni, JD; Buckley, MJ; Decker, MW; Giardina, WJ; Kang, CH; Kim, DJ; Radek, RJ; Raszkiewicz, JL; Sullivan, JP; Wasicak, JT | 1 |
Kita, T; Nakashima, T; Okamoto, M; Okuda, H; Tanaka, T | 2 |
Mimaki, Y; Sashida, Y; Yamada, K | 1 |
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Saraswati, M | 1 |
Borlongan, CV; Sanberg, PR; Shytle, RD | 1 |
Cui, WY; Liu, CG; Wang, H | 1 |
Abood, LG; Journet, M; Kende, AS; Rubin, L; Sharma, VK; Sheu, SS; Wang, DX | 1 |
Cui, WY; Gao, ZG; Liu, BY; Liu, CG; Wang, L | 1 |
Blanchette, JM; Collins, AC; Stitzel, JA | 1 |
Cui, WY; Fan, QH; Gao, ZG; Li, LJ; Liu, BY; Liu, CG | 1 |
Lu, XQ; Wang, H; Zhang, YF | 1 |
Carroll, FI; Damaj, MI; Martin, BR; Slemmer, JE | 1 |
Diler, AS; Uzüm, G; Ziylan, YZ | 1 |
Damaj, MI; Dukat, M; Glassco, W; Martin, BR | 1 |
Collins, AC; Jimenez, M; Marks, MJ; Stitzel, JA; Tritto, T | 1 |
Boyce, S; Hill, RG; Rupniak, NMJ; Russell, MGN; Shepheard, SL; Webb, JK | 1 |
Collins, AC; Jimenez, M; Lu, Y; Stitzel, JA; Tritto, T | 1 |
Damaj, MI | 1 |
Carlson, J; Ellison, G; Noguchi, K | 1 |
Brown, S; Ennifar, S; Fattom, A; Hieda, Y; Keyler, DE; Pentel, PR; Tuncok, Y | 1 |
Alves, C; Barbosa, E; Gonçalves, FR; Lopes, L; Nunes, JP | 1 |
Manresa, JJ; Newman, MB; Sanberg, PR; Shytle, RD | 1 |
Bassetto, L; Broide, R; De Biasi, M; Franceschini, D; Gotti, C; Paylor, R; Salas, R | 1 |
Broide, RS; Dani, JA; De Biasi, M; Ji, D; Patrick, JW; Paylor, R; Salas, R | 1 |
Gil, Z; Harmelin, A; Kedmi, M; Orr-Urtreger, A; Sack, RA | 1 |
Dawson, R; de Fiebre, CM; de Fiebre, NC | 1 |
Aceto, MD | 1 |
Chidester, C; Duchamp, DJ; Gall, M; Lahti, RA; Rudzik, AD; Scahill, T | 1 |
Alpern, HP; Greer, CA | 1 |
Connor, J; Connor, T; Marshall, PB; Reid, A; Turnbull, MJ | 1 |
Schlesinger, K; Tepper, JM; Wilson, JR | 1 |
Abood, LG; Booth, H; Lowy, K; Tometsko, A | 1 |
Emmert, ED; Graham, BE; Lednicer, D; Rudzik, AD | 1 |
Elegbe, RA; Oyebola, DD | 1 |
Kamdar, BV; Moffett, RB; Von Voigtlander, PF | 1 |
Barry, H; Sofia, RD; Solomon, TA | 1 |
Kita, T; Nakashima, T; Okamoto, M; Okuda, H | 1 |
Bardgett, ME; Gray, BC; Miller, JW | 1 |
Abood, LG; Hashmi, M; Saraswati, M | 1 |
Collins, AC; Freund, RK; Luntz-Leybman, V | 1 |
Janz, T; Singer, J | 1 |
Collins, AC; Miner, LL | 3 |
Gothóni, P; Ikola, W | 1 |
Beleslin, DB; Krstić, SK | 1 |
Alvarado-Garcia, R; Lee, MA; Witkin, JM; Witkin, KM | 1 |
Ishikawa, T; Nagata, M; Osumi, Y | 1 |
Gogolák, G; Liebeswar, G; Stumpf, C | 1 |
Izquierdo, I; Nasello, AG | 1 |
Zejmal, EV | 1 |
György, L; Molnár, J; Nádor, K; Pfeifer, KA | 1 |
Inoki, R; Otori, K; Yamamoto, I | 1 |
Beckett, AH; Hunter, WH; Kourounakis, P | 1 |
Aceto, MD; Bentley, HC; Dembinski, JR | 1 |
Dhasmana, KM; Dixit, KS; Kohli, RP; Saxena, RC | 2 |
Dhawan, BN; Singh, HK; Srimal, RC | 1 |
Izquierdo, I | 1 |
Lampe, KF | 1 |
Emmert, DE; Lahti, R; Lednicer, D; Rudzik, AD | 3 |
Hester, JB; Moffett, RB | 1 |
Hudson, DB; Meisami, E; Timiras, PS | 1 |
Weiner, ML; Weiner, PH | 1 |
Chiou, CY; Wecker, L | 1 |
Bhandari, DS; Singh, KP | 1 |
Claassen, V; Davies, JE; Dhasmana, KM; Spilker, BA | 1 |
Bite, A; Dóda, M; György, L; Phan, DV | 1 |
Laville, C; Margarit, J | 1 |
Beaumont, JL; Buxtorf, JC; Cahn, J; Denis, JC; Jacotot, B; Patois, E; Rambaud, J | 1 |
McCulloch, JA; Ursillo, RC | 1 |
Hester, JB; Lemke, TL; Rudzik, AD | 1 |
Moffett, RB; Rudzik, AD | 1 |
Inoki, R; Nagai, K; Yamamoto, I | 1 |
Inoki, R; Iwatsubo, K; Tamari, Y; Yamamoto, I | 1 |
Hester, JB; Rudzik, AD; Veldkamp, W | 1 |
Zakhariia, EA; Zapadniuk, VI | 1 |
Hoffmann, I; Kuch, H; Schmitt, K; Seidl, G | 1 |
de Carolis, AS; Longo, VG | 1 |
Andrews, TL; Miskus, RP | 1 |
Leszkovszky, GP; Sebestyén, G; Takács, K; Tardos, L | 1 |
Krip, G; Pinsky, C; Vazquez, AJ | 1 |
Bertazzoli, C; Bonsignori, A; Chieli, T; Pegrassi, L; Suchowsky, GK | 1 |
Bernard, PJ; De Schaepdryver, AF; Delaunois, AL; Piette, Y | 1 |
Lendvai, J; Leszkovszky, G; Takács, K; Tardos, L | 1 |
6 review(s) available for nicotine and Absence Seizure
Article | Year |
---|---|
Vaping implications for children and youth.
Topics: Adolescent; Burns; Child; Electronic Nicotine Delivery Systems; Humans; Lung Injury; Nicotine; Seizures; Students; Vaping | 2020 |
Tolerability and safety of sustained-release bupropion in the management of smoking cessation.
Topics: Bupropion; Clinical Trials as Topic; Consumer Product Safety; Delayed-Action Preparations; Dopamine Uptake Inhibitors; Humans; Nicotine; Seizures; Sleep Initiation and Maintenance Disorders; Smoking Cessation; Tobacco Use Disorder; Xerostomia | 2002 |
Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Body Temperature; Brain; Mice; Mice, Mutant Strains; Models, Animal; Nicotine; Nicotinic Agonists; Point Mutation; Receptors, Nicotinic; Seizures | 2003 |
Pharmacology of the brain: the hippocampus, learning and seizures.
Topics: Acetylcholine; Aminobutyrates; Amphetamine; Animals; Anura; Brain Chemistry; Dronabinol; Electric Stimulation; Evoked Potentials; Glutamates; Hippocampus; Learning; Nicotine; Norepinephrine; Osmolar Concentration; Phenytoin; Physostigmine; Potassium; Rats; RNA; Seizures; Serotonin; Stimulation, Chemical; Synaptic Transmission | 1972 |
Hippocampal physiology: experiments on regulation of its electrical activity, on the mechanism of seizures, and on a hypothesis of learning.
Topics: Amphetamine; Animals; Electric Stimulation; Electroencephalography; Electrophysiology; Evoked Potentials; Hippocampus; Ions; Learning; Mice; Neurons; Nicotine; Physostigmine; Potassium; Protein Biosynthesis; Rabbits; Rats; RNA; Seizures | 1972 |
Systemic plant poisoning in children.
Topics: Albumins; Alkaloids; Atropine; Atropine Derivatives; Basidiomycota; Charcoal; Child; Digitalis; Gastroenteritis; Humans; Mouth; Mushroom Poisoning; Nicotine; Phenytoin; Physostigmine; Plant Poisoning; Plants; Plants, Medicinal; Plants, Toxic; Poisons; Potassium Chloride; Renal Dialysis; Seizures; Toxins, Biological; Vomiting; Water-Electrolyte Balance | 1974 |
157 other study(ies) available for nicotine and Absence Seizure
Article | Year |
---|---|
The β2
Topics: Acetylcholine; Animals; Epilepsy; Humans; Mice; Mice, Transgenic; Neurons; Nicotine; Prefrontal Cortex; Receptors, Nicotinic; Seizures; Sleep; Somatostatin | 2022 |
How do smoking, vaping, and nicotine affect people with epilepsy and seizures? A scoping review protocol.
Topics: Epilepsy; Humans; Nicotine; Research Design; Review Literature as Topic; Seizures; Smoking; Smoking Cessation; Systematic Reviews as Topic; Tobacco Smoking; Tobacco Use Cessation Devices; Vaping | 2023 |
Seizures After Vaping Nicotine in Youth: A Canary or a Red Herring?
Topics: Adolescent; Electronic Nicotine Delivery Systems; Humans; Nicotine; Seizures; Vaping; Young Adult | 2020 |
Adverse Experience Reports of Seizures in Youth and Young Adult Electronic Nicotine Delivery Systems Users.
Topics: Adolescent; Adult; Cannabis; Electronic Nicotine Delivery Systems; Humans; Nicotine; Seizures; Tobacco Products; Vaping; Young Adult | 2020 |
Increased Seizure Frequency Temporally Related to Vaping: Where There's Vapor, There's Seizures?
Topics: Adolescent; Epilepsy, Generalized; Female; Humans; Nicotine; Nicotinic Agonists; Seizures; Vaping | 2020 |
Severe Acute Toxicity of Inhaled Nicotine and e-Cigarettes: Seizures and Cardiac Arrhythmia.
Topics: Administration, Inhalation; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Arrhythmias, Cardiac; Autonomic Fibers, Preganglionic; Electronic Nicotine Delivery Systems; Humans; Medulla Oblongata; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Respiratory Center; Respiratory Insufficiency; Seizures; Vaping | 2020 |
Measuring functional brain recovery in regenerating planarians by assessing the behavioral response to the cholinergic compound cytisine.
Topics: Alkaloids; Anesthetics, Local; Animals; Azocines; Brain; Carbachol; Cholinergic Agents; Cocaine; Cotinine; Dose-Response Relationship, Drug; Ethanol; Nicotine; Planarians; Quinolizines; Regeneration; Seizures | 2020 |
China expands surveillance of sewage to police illegal drug use.
Topics: Caffeine; China; Cities; Humans; Illicit Drugs; Nicotine; Police; Seizures; Sewage; Wastewater | 2018 |
Protective effect of α-asarone against nicotine-induced seizures in mice, but not by its interaction with nicotinic acetylcholine receptors.
Topics: Allylbenzene Derivatives; Animals; Anisoles; Anticonvulsants; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Seizures | 2018 |
Some Young Adult E-Cigarette Users Report Seizures.
Topics: Electronic Nicotine Delivery Systems; Female; Humans; Male; Nicotine; Seizures; Smoking; Young Adult | 2019 |
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings.
Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Epilepsy, Frontal Lobe; Fenofibrate; Frontal Lobe; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Nicotine; Patch-Clamp Techniques; Phosphorylation; PPAR alpha; Pyramidal Cells; Pyrimidines; Rats; Receptors, Nicotinic; Seizures | 2013 |
Nicotine decreases the activity of glutamate transporter type 3.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Membrane Potentials; Nicotine; Nicotinic Agonists; Oocytes; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Rats; Seizures; Time Factors; Xenopus laevis | 2014 |
Evidence of Nicotine-Induced, Curare-Insensitive, Behavior in Planarians.
Topics: Animals; Behavior, Animal; Curare; Movement; Nicotine; Planarians; Seizures | 2015 |
A case of nicotine overdose-induced seizure on an inpatient psychiatric unit.
Topics: Adult; Drug Overdose; Female; Humans; Nicotine; Psychotic Disorders; Seizures; Tobacco Use Cessation Devices | 2016 |
Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Caudate Nucleus; Cholinergic Neurons; Disease Susceptibility; Gene Deletion; Hippocampus; Male; Methyl-CpG-Binding Protein 2; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Nicotine; Phenotype; Prosencephalon; Rett Syndrome; Seizures; Signal Transduction | 2016 |
Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Blood Pressure; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Eclampsia; Female; Lipopolysaccharides; Microglia; Neuroimmunomodulation; Neurons; Nicotine; Nicotinic Agonists; Pentylenetetrazole; Pregnancy; Pregnancy Outcome; Random Allocation; Rats, Sprague-Dawley; Seizures | 2016 |
Enhanced brain penetration of hexamethonium in complexes with derivatives of fullerene C60.
Topics: Aminocaproates; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Fullerenes; Hexamethonium Compounds; Locomotion; Male; Mice; Nicotine; Nicotinic Antagonists; Rats, Wistar; Seizures | 2016 |
Dose-finding study with nicotine as a proconvulsant agent in PTZ-induced seizure model in mice.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fructose; Ganglionic Stimulants; Male; Mice; Nicotine; Pentylenetetrazole; Seizures; Topiramate; Valproic Acid | 2008 |
Peripheral and central routes of administration of quaternary ammonium compound IEM-1460 are equally potent in reducing the severity of nicotine-induced seizures in mice.
Topics: Adamantane; Animals; Biguanides; Male; Mice; Nicotine; Receptors, AMPA; Receptors, Nicotinic; Seizures | 2008 |
YB-1 binds to GluR2 mRNA and CaM1 mRNA in the brain and regulates their translational levels in an activity-dependent manner.
Topics: Adrenergic alpha-Agonists; Animals; Brain; Calmodulin; Carbachol; Cell Line; Cholinergic Agonists; Excitatory Amino Acid Agonists; Gene Expression Regulation; Kainic Acid; Mice; Nicotine; Nicotinic Agonists; Norepinephrine; Protein Isoforms; Rats; Receptors, AMPA; Recombinant Fusion Proteins; RNA, Messenger; RNA, Small Interfering; Seizures; Transcription Factors; Y-Box-Binding Protein 1 | 2010 |
Levamisole-induced reduction in seizure threshold: a possible role of nicotinic acetylcholine receptor-mediated pathway.
Topics: Animals; Antinematodal Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Levamisole; Male; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Seizures | 2010 |
Nicotine effects on rat seizures susceptibility and hippocampal neuronal degeneration.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electrodes, Implanted; Electrophysiology; Evoked Potentials; Hippocampus; Injections, Intraperitoneal; Motor Cortex; Nerve Degeneration; Neurons; Nicotine; Nicotinic Agonists; Random Allocation; Rats; Rats, Wistar; Seizures | 2010 |
Carbamazepine inhibits distinct chemoconvulsant-induced seizure-like activity in Dugesia tigrina.
Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; N-Methylaspartate; Nicotine; Nicotinic Agonists; Oxcarbazepine; Picrotoxin; Planarians; Seizures; Structure-Activity Relationship | 2011 |
Nicotine reversal of anticonvulsant action of topiramate in kainic acid-induced seizure model in mice.
Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Fructose; Humans; Kainic Acid; Lipid Peroxidation; Male; Mecamylamine; Mice; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Seizures; Topiramate | 2011 |
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.
Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Drug Synergism; Eating; Ethanol; Female; Food Preferences; Gene Knock-In Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Skills; Mutation; N-Methylaspartate; Nicotine; Pentylenetetrazole; Quinine; Receptors, Glycine; Reflex, Righting; Reflex, Startle; Rotarod Performance Test; Saccharin; Seizures; Sex Characteristics; Strychnine; Taste Perception | 2012 |
Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
Topics: Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Cloning, Molecular; Corpus Striatum; Dose-Response Relationship, Drug; Female; Gene Expression; Genetic Engineering; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Multigene Family; Nerve Tissue Proteins; Nicotine; Phenotype; Proto-Oncogene Proteins c-fos; Radionuclide Imaging; Receptors, Nicotinic; Seizures; Self Administration; Tobacco Use Disorder | 2012 |
Effect of hydroalcoholic extract of Lavandula officinalis on nicotine-induced convulsion in mice.
Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Lavandula; Male; Mice; Nicotine; Nicotinic Agonists; Plant Extracts; Seizures | 2011 |
Planarians in pharmacology: parthenolide is a specific behavioral antagonist of cocaine in the planarian Girardia tigrina.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Methamphetamine; N-Methylaspartate; Nicotine; Nicotinic Agonists; Planarians; Regeneration; Seizures; Sesquiterpenes | 2012 |
The effect of dorsal hippocampal administration of nicotinic and muscarinic cholinergic ligands on pentylenetetrazol-induced generalized seizures in rats.
Topics: Animals; Atropine; Hippocampus; Male; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Oxotremorine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures | 2012 |
Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function.
Topics: Acetylcholine; Animals; Body Temperature; Central Nervous System Sensitization; Cerebral Cortex; Dopamine; Dystonia; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Hippocampus; Male; Mice; Motor Activity; Mutation, Missense; Nicotine; Presynaptic Terminals; Radioligand Assay; Receptors, Nicotinic; Rubidium Radioisotopes; Seizures; Synaptosomes | 2013 |
The relationship between hippocampal acetylcholine release and cholinergic convulsant sensitivity in withdrawal seizure-prone and withdrawal seizure-resistant selected mouse lines.
Topics: Acetylcholine; Alcohol Withdrawal Seizures; Animals; Carbachol; Cholinergic Agents; Convulsants; Hippocampus; Male; Mice; Neostigmine; Nicotine; Seizures; Species Specificity | 2002 |
Are neuronal nicotinic receptors a target for antiepileptic drug development? Studies in different seizure models in mice and rats.
Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Female; Hippocampus; In Vitro Techniques; Injections, Subcutaneous; Kindling, Neurologic; Mice; Motor Activity; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Seizures | 2003 |
Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.
Topics: Animals; Behavior, Animal; Brain; Electroencephalography; Female; Gene Dosage; Hippocampus; Male; Mice; Mice, Neurologic Mutants; Nicotine; Nicotinic Agonists; Phenotype; Receptors, Nicotinic; Seizures; Tail; Theta Rhythm | 2003 |
The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Drosophila Proteins; Locomotion; Mice; Mice, Knockout; Mutation; Nicotine; Protein Subunits; Receptors, Nicotinic; Seizures | 2003 |
Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.
Topics: Age Factors; Animals; Attention; Behavior, Animal; Choice Behavior; Cholinesterase Inhibitors; Cognition; Discrimination Learning; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Indans; Lethal Dose 50; Male; Mecamylamine; Memory, Short-Term; Mice; Mice, Inbred C57BL; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenols; Piperidines; Psychomotor Performance; Pyrrolidines; Reaction Time; Receptors, Nicotinic; Scopolamine; Seizures | 2003 |
[Electroencephalographic study on antagonism of anti-epileptic drugs to tremors produced by nicotine].
Topics: Electroencephalography; Humans; Nicotine; Seizures; Tremor | 1952 |
Mechanism of the prevention of nicotine convulsions by hexamethonium and by adrenaline blocking agents.
Topics: Adrenal Glands; Biomedical Research; Colorimetry; Epinephrine; Hexamethonium; Humans; Muscle Relaxants, Central; Nicotine; Norepinephrine; Seizures; Sympatholytics | 1953 |
Nicotine convulsions and their modification by reserpine and chlorpromazine.
Topics: Chlorpromazine; Nicotine; Reserpine; Seizures | 1962 |
THE INHIBITION OF NICOTINE-INDUCED CONVULSIONS IN THE RAT.
Topics: Anesthetics; Anesthetics, Local; Anticonvulsants; Nicotine; Pharmacology; Phenobarbital; Procaine; Rats; Research; Seizures | 1963 |
THIAMINE AS A NICOTINE ANTAGONIST.
Topics: Animals; Antimetabolites; Anura; Blood Pressure; Blood Pressure Determination; Bufonidae; Cats; Dogs; Ear, External; Guinea Pigs; Heart; Hyperglycemia; Intestine, Small; Intestines; Nicotine; Nictitating Membrane; Pharmacology; Rabbits; Research; Seizures; Thiamine; Toxicology | 1963 |
[STUDIES ON NICOTINE. CHANGES IN CATECHLOAMINES IN RATS WITH NICOTINE-INDUCED CONVULSIONS].
Topics: Adrenal Glands; Adrenalectomy; Brain; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Epinephrine; Heart; Monoamine Oxidase Inhibitors; Nicotine; Norepinephrine; Rats; Research; Seizures | 1963 |
[THE BIOELECTRIC ACTIVITY OF THE CENTRAL AND SYMPATHETIC NERVOUS SYSTEMS IN CAMPHOR, NICOTINE AND PICROTOXIN-INDUCED SEIZURES].
Topics: Autonomic Nervous System; Camphor; Electroencephalography; Ganglia; Ganglia, Autonomic; Hypothalamus; Nicotine; Pharmacology; Picrotoxin; Rabbits; Research; Seizures; Sympathetic Nervous System; Toxicology | 1963 |
[THE EFFECT OF NANOPHYNE, PACHYCARPINE AND GANGLERONE ON THE ACTIVATING AND CONVULSIVE EFFECTS OF NICOTINE].
Topics: Animals; Benzoates; Cats; Electroencephalography; Ganglionic Blockers; Lagomorpha; Nicotine; Pharmacology; Rabbits; Research; Seizures; Sparteine; Toxicology | 1963 |
SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF PHENYL-SUBSTITUTED BIURETS.
Topics: Atropine; Biuret; Chemistry, Pharmaceutical; Gastric Juice; Meprobamate; Mice; Nicotine; Pentylenetetrazole; Peptic Ulcer; Pharmacology; Phenformin; Phenobarbital; Picrotoxin; Rats; Research; Seizures; Strychnine; Toxicology; Urea | 1963 |
EFFECTS OF MONOAMINE RELEASERS ON THE TREMOR CONVULSIONS AND LETHAL EFFECTS OF NICOTINE IN MICE.
Topics: Alkaloids; Amines; Dopamine; Hypnotics and Sedatives; Methyldopa; Mice; Nicotine; Pharmacology; Rauwolfia; Research; Reserpine; Seizures; Tetrabenazine; Toxicology; Tremor | 1964 |
[CENTRAL EFFECT OF SOME CHOLINERGIC SUBSTANCES FOLLOWING THEIR INTRAVENOUS ADMINISTRATION AND AFTER THEIR INTRODUCTION INTO THE LATERAL CEREBRAL VENTRICLE IN THE MOUSE].
Topics: Acetylcholine; Administration, Intravenous; Animals; Cerebral Ventricles; Cholinergic Agents; Hexamethonium Compounds; Injections; Injections, Intravenous; Mice; Nicotine; Parasympathomimetics; Pharmacology; Research; Seizures | 1964 |
[ON THE CHARACTERISTICS OF CENTRAL CHOLINE RECEPTORS SIMULATED BY NICOTINE].
Topics: Animals; Cerebral Ventricles; Choline; Hexamethonium Compounds; Mice; Muscle Relaxants, Central; Nicotine; Pharmacology; Research; Seizures; Sensory Receptor Cells | 1964 |
[PHARMACOLOGICAL STUDIES ON ANTAGONISTS TO NICOTINE-INDUCED CONVULSIONS AND DEATH].
Topics: Anticonvulsants; Hypnotics and Sedatives; Mice; Nicotine; Pharmacology; Research; Seizures; Toxicology; Tranquilizing Agents | 1964 |
The effect of methonium compounds on nicotine convulsions.
Topics: Bis-Trimethylammonium Compounds; Drug-Related Side Effects and Adverse Reactions; Epinephrine; Muscle Relaxants, Central; Nicotine; Seizures | 1952 |
Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures.
Topics: Animals; Brain; Female; Gene Expression; Kinetics; Male; Mice; Mice, Knockout; Mice, Transgenic; Nicotine; Nicotinic Agonists; Protein Subunits; Receptors, Nicotinic; Seizures | 2004 |
Tolerance to pentylentetrazol-induced convulsions and protection of cerebrovascular integrity by chronic nicotine.
Topics: Analysis of Variance; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebrovascular Circulation; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Evans Blue; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Specific Gravity; Time Factors | 2004 |
The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.
Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Female; Gene Expression; In Situ Hybridization; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nicotine; Nicotinic Agonists; Protein Subunits; Receptors, Nicotinic; RNA, Messenger; Seizures; Sex Factors | 2004 |
Pharmacological and histological characterisation of nicotine-kindled seizures in mice.
Topics: Animals; Brain Chemistry; Immunohistochemistry; Kindling, Neurologic; Male; Mice; Nicotine; Seizures | 2005 |
Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats.
Topics: Animals; Body Weight; Ethanol; Hippocampus; Male; Motor Activity; Nicotine; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome | 2005 |
Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Administration, Cutaneous; Adult; Aged; Anticonvulsants; Epilepsy, Frontal Lobe; Female; Humans; Male; Middle Aged; Mutation; Nicotine; Receptors, Nicotinic; Seizures; Sleep; Smoking | 2006 |
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
Topics: Aconitine; Analgesics; Animals; Anticonvulsants; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Data Interpretation, Statistical; In Vitro Techniques; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Pain Measurement; Pyridines; Rats; Reaction Time; Receptors, Nicotinic; Seizures | 2007 |
Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.
Topics: Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Frontal Lobe; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Mice, Transgenic; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Seizures | 2006 |
Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Dihydro-beta-Erythroidine; DNA; Hippocampus; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Mecamylamine; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Transcription Factor AP-1 | 2007 |
alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Gene Expression Regulation; Genotype; Humans; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Nicotinic Agonists; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptors, Nicotinic; Seizures; Species Specificity | 2007 |
Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks.
Topics: Animals; Brain; Drug Resistance; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Nicotine; Oligonucleotide Array Sequence Analysis; Receptors, Nicotinic; Seizures; Transcription Factors; Transcription, Genetic | 2007 |
Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats.
Topics: Allosteric Site; Aniline Compounds; Animals; Cell Membrane; Dose-Response Relationship, Drug; Electrophysiology; Feeding Behavior; Ligands; Male; Mice; Motor Activity; Naphthalenes; Nicotine; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Self Administration; Tobacco Use Disorder; Xenopus laevis | 2007 |
Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome.
Topics: Aging; Animals; Behavior, Animal; Blotting, Western; Body Temperature; Brain; Disease Models, Animal; Female; Male; Nicotine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Solvents; Toluene | 2008 |
Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.
Topics: Adrenergic alpha-Antagonists; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Idazoxan; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Norepinephrine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission | 2008 |
Interactions of the anticonvulsant carbamazepine with adenosine receptors. 2. Pharmacological studies.
Topics: Animals; Carbamazepine; Guinea Pigs; Ileum; Male; Mice; Mice, Inbred Strains; Nicotine; Purines; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline | 1983 |
[Pharmacodynamic effects of d-nicotine--Comparison with l-nicotine].
Topics: Animals; Cardiovascular System; Conditioning, Operant; Electroencephalography; Gastrointestinal Motility; Macaca mulatta; Male; Mice; Mice, Inbred ICR; Motor Activity; Neuromuscular Junction; Nicotine; Rats; Seizures; Stereoisomerism | 1984 |
Classical genetic analysis of nicotine-induced seizures and nicotinic receptors.
Topics: Animals; Bungarotoxins; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iodine Radioisotopes; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures; Species Specificity; Tritium | 1984 |
Effects of mecamylamine, nicotine, atropine and physostigmine on the phencyclidine-induced behavioral toxicity.
Topics: Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Phencyclidine; Physostigmine; Seizures | 1984 |
Mediation of nicotine-induced convulsions by central nicotinic receptors of the 'C6' type.
Topics: Animals; Drug Synergism; Ganglionic Stimulants; Injections, Intraventricular; Male; Mice; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Seizures | 1983 |
[Phenothiazine carboxamides that have anticholinergic properties].
Topics: Animals; Behavior, Animal; Convulsants; Dogs; Mice; Nicotine; Parasympatholytics; Pentylenetetrazole; Phenothiazines; Salivation; Seizures; Tears; Tremor; Trihexyphenidyl | 1980 |
(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.
Topics: Alzheimer Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Behavior, Animal; Body Temperature; Brain; Cerebrovascular Circulation; Cognition; Electroencephalography; Isoxazoles; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Nociceptors; Pyrrolidines; Rats; Rats, Wistar; Receptors, Cholinergic; Seizures; Vomiting | 1994 |
Effects of aging on acute toxicity of nicotine in rats.
Topics: Aging; Animals; Brain; Corticosterone; Cytochrome P-450 Enzyme System; Dopamine; Injections, Intraperitoneal; Liver; Male; Nicotine; Oxidoreductases; Oxygenases; Rats; Rats, Wistar; Seizures | 1994 |
Anticonvulsive effects of inhaling lavender oil vapour.
Topics: Administration, Inhalation; Animals; Anticonvulsants; Lavandula; Male; Mice; Nicotine; Oils, Volatile; Pentylenetetrazole; Plant Extracts; Plant Oils; Seizures; Strychnine | 1994 |
Affinity ligands and related agents for brain muscarinic and nicotinic cholinergic receptors.
Topics: Affinity Labels; Animals; Brain; Carbachol; Choline; Kinetics; Ligands; Mice; Naloxone; Nicotine; Oxotremorine; Procaine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Tritium | 1993 |
Nicotine blocks kainic acid-induced wet dog shakes in rats.
Topics: Animals; Kainic Acid; Male; Nicotine; Rats; Rats, Sprague-Dawley; Seizures | 1995 |
Regulatory effects of acutely repeated nicotine treatment towards central muscarinic receptors.
Topics: Animals; Brain; Down-Regulation; Electroencephalography; Female; Male; Mice; Muscarinic Agonists; Nicotine; Rabbits; Rats; Rats, Wistar; Receptors, Muscarinic; Seizures | 1996 |
[3H]benzylpempidine, a new radioligand for probing a putative channel site on nicotinic cholinergic receptors.
Topics: Animals; Binding, Competitive; Brain; Calcium; Calcium Channels; Cattle; Cell Membrane; Ligands; Mecamylamine; Mice; Nicotine; Nicotinic Antagonists; Pempidine; Receptors, Nicotinic; Seizures | 1997 |
Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives.
Topics: Animals; Arecoline; Brain; Drug Antagonism; Female; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Stereoisomerism; Structure-Activity Relationship; Tremor; Tropanes | 1997 |
Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes.
Topics: Animals; Brain; Bungarotoxins; Genotype; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Polymorphism, Genetic; Receptors, Nicotinic; Seizures; Species Specificity | 1998 |
Anti-nicotinic properties of anticholinergic antiparkinson drugs.
Topics: Animals; Antiparkinson Agents; Atropine; Brain; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Protein Binding; Rats; Seizures | 1998 |
Modulation of phosphatidylinositol turnover on central nicotinic receptors.
Topics: Animals; Brain; Lithium Chloride; Male; Mice; Muscarinic Agonists; Nicotine; Oxotremorine; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Receptors, Nicotinic; Seizures | 1997 |
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
Topics: Animals; Body Temperature; Bupropion; Cocaine; Discrimination, Psychological; Female; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Molecular Structure; Motor Activity; Nicotine; Oocytes; Pain; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Seizures; Structure-Activity Relationship; Tropanes; Xenopus laevis | 1999 |
Chronic nicotine pretreatment protects the blood-brain barrier against nicotine-induced seizures in the rat.
Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Dose-Response Relationship, Drug; Male; Nicotine; Premedication; Rats; Rats, Wistar; Seizures | 1999 |
Pharmacological characterization of nicotine-induced seizures in mice.
Topics: Animals; Anticonvulsants; Brain Chemistry; Calcium Signaling; Dihydropyridines; Glutamic Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Seizures | 1999 |
Potential role of the alpha4 and alpha6 nicotinic receptor subunits in regulating nicotine-induced seizures.
Topics: Animals; Behavior, Animal; Blotting, Southern; DNA; Dose-Response Relationship, Drug; Gene Transfer Techniques; In Situ Hybridization; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Seizures; Species Specificity | 2000 |
Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats.
Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Behavior, Animal; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Hot Temperature; Hypertension; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Postural Balance; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Substance-Related Disorders | 2000 |
Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors.
Topics: Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Behavior, Animal; Crosses, Genetic; Dose-Response Relationship, Drug; Female; Hippocampus; Humans; Hybridization, Genetic; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Polymorphism, Restriction Fragment Length; Quinolizines; Receptors, Nicotinic; Seizures | 2000 |
Influence of gender and sex hormones on nicotine acute pharmacological effects in mice.
Topics: Animals; Body Temperature; Electrophysiology; Female; Gonadal Steroid Hormones; In Vitro Techniques; Injections, Spinal; Male; Maze Learning; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Nicotine; Nicotinic Agonists; Oocytes; Pain Measurement; Reaction Time; Receptors, Nicotinic; Seizures; Sex Factors; Xenopus laevis | 2001 |
Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus.
Topics: Animals; Axons; Body Weight; Cotinine; Dose-Response Relationship, Drug; Efferent Pathways; Female; Habenula; Hyperkinesis; Nerve Degeneration; Neurotoxins; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Seizures; Silver Staining; Wallerian Degeneration | 2001 |
Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion.
Topics: Animals; Brain; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Haptens; Immunoglobulin E; Infusions, Intravenous; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Seizures; Vaccination | 2001 |
Nicotine nasal inhalation, atrial fibrillation and seizures.
Topics: Administration, Inhalation; Atrial Fibrillation; Ganglionic Stimulants; Humans; Male; Middle Aged; Nicotine; Seizures; Substance-Related Disorders | 2001 |
Nicotine induced seizures blocked by mecamylamine and its stereoisomers.
Topics: Animals; Disease Models, Animal; Male; Mecamylamine; Molecular Conformation; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Seizures | 2001 |
Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dose-Response Relationship, Drug; Female; Hippocampus; Injections, Intraperitoneal; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Protein Subunits; Pyridines; Receptors, Nicotinic; RNA, Messenger; Seizures | 2002 |
Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Electrophysiology; Female; Ganglionic Stimulants; Heterozygote; Hippocampus; Lysine; Male; Mice; Mice, Inbred C57BL; Neuroanatomy; Nicotine; Phenotype; Receptors, Nicotinic; Seizures; Threonine | 2002 |
Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Electroencephalography; Ganglionic Stimulants; Genetic Predisposition to Disease; Heterozygote; Mice; Mice, Inbred C57BL; Mortality; Mutation; Nicotine; Receptors, Nicotinic; Reference Values; Seizures | 2002 |
The selectively bred high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats differ in sensitivity to nicotine.
Topics: Alcohol Drinking; Animals; Body Temperature; Brain; Female; Male; Motor Activity; Nicotine; Rats; Seizures | 2002 |
The antinicotinic effects of drugs with clinically useful sedative-antianxiety properties.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Hypnotics and Sedatives; Male; Mice; Nicotine; Seizures | 1975 |
Novel anxiolytic agents derived from alpha-amino-alpha-phenyl-o-tolyl-4H-triazoles and -imidazoles.
Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Crystallography; Hypnotics and Sedatives; Imidazoles; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Models, Molecular; Molecular Conformation; Muscle Relaxation; Nicotine; Pentylenetetrazole; Rats; Seizures; Semicarbazides; Triazoles | 1978 |
Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility.
Topics: Aging; Animals; Cocaine; Dextroamphetamine; Dopamine; Mice; Myoclonus; Nicotine; Seizures; Strychnine | 1979 |
The pharmacology of Avena sativa.
Topics: Animals; Barbiturates; Blood Pressure; Humans; Mice; Morphine; Morphine Dependence; Nicotine; Plant Extracts; Plants; Plants, Medicinal; Rats; Reaction Time; Seizures; Sleep; Time Factors | 1975 |
Relations between nicotine-induced convulsive behavior and blood and brain levels of nicotine as a function of sex and age in two inbred strains of mice.
Topics: Aging; Animals; Brain; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nicotine; Seizures; Sex Factors; Species Specificity | 1979 |
Electrophysiological, behavioral, and chemical evidence for a noncholinergic, stereospecific site for nicotine in rat brain.
Topics: Action Potentials; Animals; Behavior, Animal; Brain Mapping; Hippocampus; Male; Nicotine; Rats; Receptors, Cholinergic; Receptors, Nicotinic; Seizures; Stereoisomerism | 1978 |
Butyrophenones as hypotensive agents. Derivatives of 4-aryl-4-(hydroxymethyl)cyclohexylamine.
Topics: Animals; Behavior, Animal; Blood Pressure; Butyrophenones; Cyclohexylamines; Depression, Chemical; Male; Methanol; Mice; Nicotine; Rats; Seizures | 1975 |
Cow's urine poisoning in Nigeria. Experimental observations in mice.
Topics: Animals; Cattle; Child; Dogs; Dose-Response Relationship, Drug; Female; Folklore; Humans; Injections, Intraperitoneal; Male; Medicine, Traditional; Mice; Nicotine; Nigeria; Pharmaceutical Vehicles; Plant Extracts; Rabbits; Rats; Seizures; Urine | 1975 |
Central nervous system depressants. 13. s-Triazolo-1,5-benzodiazepin-5-ones.
Topics: Animals; Benzodiazepinones; Central Nervous System; Depression, Chemical; Male; Mice; Nicotine; Pentylenetetrazole; Reflex; Seizures; Strychnine; Triazoles | 1976 |
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.
Topics: Animals; Anticonvulsants; Cannabis; Chlordiazepoxide; Dronabinol; Electroshock; Male; Mice; Nicotine; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Seizures; Strychnine; Time Factors | 1976 |
Effects of acute administration of nicotine on convulsive movements and blood levels of corticosterone in old rats.
Topics: Aging; Animals; Corticosterone; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Male; Movement; Nicotine; Rats; Rats, Wistar; Seizures; Spectrophotometry, Ultraviolet; Tremor | 1992 |
Tolerance to the convulsions induced by daily nicotine treatment in rats.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Injections, Intraperitoneal; Male; Nicotine; Rats; Rats, Wistar; Seizures; Time Factors; Tremor | 1992 |
Characterization of cholinergic regulation of seizures by the midline thalamus.
Topics: Animals; Female; Neostigmine; Nicotine; Parasympathomimetics; Pentylenetetrazole; Pilocarpine; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Seizures; Thalamus; Tubocurarine | 1992 |
4-Bromoacetamidoprocaine: an affinity ligand for brain muscarinic and nicotinic cholinergic receptors.
Topics: Animals; Behavior, Animal; Brain; Carbachol; Chloromercuribenzoates; Hyperkinesis; Ligands; Mercaptoethanol; Molecular Structure; Naloxone; Nicotine; p-Chloromercuribenzoic Acid; Procaine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Receptors, Nicotinic; Seizures | 1992 |
5 alpha-Pregnan-3 alpha-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition.
Topics: Animals; Anticonvulsants; Electric Stimulation; Electrophysiology; Hippocampus; Male; Mice; Mice, Inbred C3H; Nicotine; Pregnanolone; Seizures | 1990 |
Apnea and seizures caused by nicotine ingestion.
Topics: Apnea; Female; Humans; Infant; Male; Nicotine; Seizures | 1990 |
Strain comparison of nicotine-induced seizure sensitivity and nicotinic receptors.
Topics: Animals; Brain Chemistry; Bungarotoxins; Dose-Response Relationship, Drug; Infusions, Intravenous; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Nicotine; Reaction Time; Receptors, Nicotinic; Seizures; Species Specificity | 1989 |
Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine.
Topics: Animals; Ethanol; Hexamethonium; Hexamethonium Compounds; Male; Nicotine; Propranolol; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Tremor | 1985 |
Nicotine-induced convulsions in cats and central nicotinic receptors.
Topics: 5,6-Dihydroxytryptamine; Animals; Brain; Cats; Dopamine Antagonists; Female; Ganglionic Blockers; Hemicholinium 3; Hydroxydopamines; Injections, Intraventricular; Male; Nicotine; Oxidopamine; Parasympatholytics; Receptors, Nicotinic; Reserpine; Seizures; Serotonin Antagonists; Sympatholytics | 1986 |
The effect of chronic nicotine treatment on nicotine-induced seizures.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain Chemistry; Drug Tolerance; Female; Mice; Mice, Inbred DBA; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Seizures | 1988 |
Genetic influences on acute responses to nicotine and nicotine tolerance in the mouse.
Topics: Animals; Body Temperature; Brain; Bungarotoxins; Drug Tolerance; Female; Heart Rate; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Receptors, Nicotinic; Reflex, Startle; Respiration; Seizures | 1988 |
Effect of nicotine pretreatment on nicotine-induced seizures.
Topics: Animals; Brain; Drug Resistance; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures; Species Specificity | 1988 |
Nonmuscarinic neurotoxicity of oxotremorine.
Topics: Animals; Arecoline; Atropine; Atropine Derivatives; Benactyzine; Benztropine; Crying; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Nervous System; Nicotine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Seizures; Time Factors | 1987 |
Genetic analysis of nicotine-induced seizures and hippocampal nicotinic receptors in the mouse.
Topics: Animals; Brain; Bungarotoxins; Hippocampus; Mathematics; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures | 1986 |
Effect of d-nicotine on the l-nicotine-induced increase in gastric acid secretion in rats.
Topics: Animals; Gastric Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Nicotine; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism | 1985 |
Relationship between nicotine-induced seizures and hippocampal nicotinic receptors.
Topics: Animals; Bungarotoxins; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures | 1985 |
[Nicotine and pentetrazol-induced EEG changes in normal and hypothyroid rabbits].
Topics: Animals; Cerebral Cortex; Electroencephalography; Hippocampus; Hypothyroidism; Iodine Isotopes; Methylthiouracil; Nicotine; Pentylenetetrazole; Perchlorates; Rabbits; Seizures; Thyroid Gland | 1967 |
Pharmacological study of the central nicotine-sensitive cholino-receptors.
Topics: Animals; Ganglionic Blockers; Mice; Muscles; Nicotine; Seizures; Sensory Receptor Cells | 1966 |
Tremorigenic and convulsant actions of intracerebrally administered vegetative poisons in the mouse.
Topics: Acetylcholine; Animals; Autonomic Nervous System; Carbachol; Central Nervous System Stimulants; Histamine; Hormones; Indoles; Mice; Nicotine; Parasympathomimetics; Physostigmine; Pilocarpine; Piperazines; Pyridines; Pyrrolidines; Quaternary Ammonium Compounds; Seizures; Serotonin; Strychnine; Tremor; Tremorine; Tubocurarine | 1967 |
Pharmacological studies on antagonists against nicotine-induced convulsions and death.
Topics: Animals; Anticonvulsants; Chlorpromazine; Drug Antagonism; Female; Ganglionic Blockers; Hexamethonium Compounds; Histamine H1 Antagonists; Male; Meprobamate; Mice; Nicotine; Parasympatholytics; Perphenazine; Phenobarbital; Phentolamine; Reserpine; Seizures; Sympatholytics; Thiazoles; Tolazoline; Tranquilizing Agents; Urea | 1966 |
Synthesis and pharmacological action of some N-alkyl morpholines and their salts.
Topics: Acetylcholine; Animals; Female; Magnetic Resonance Spectroscopy; Mice; Morpholines; Nicotine; Pain; Pentylenetetrazole; Seizures; Spectrophotometry; Ultraviolet Rays | 1968 |
Effects of ganglion blocking agents on nicotine extensor convulsions and lethality in mice.
Topics: Animals; Atropine; Cerebral Ventricles; Chlorisondamine; Chlorpromazine; Decamethonium Compounds; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Nicotine; Phenobarbital; Seizures | 1969 |
Antagonism of intracerebrally induced nicotinic convulsions in mice: a method for measuring the central antinicotinic activity of CNS acting agents.
Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Antidepressive Agents; Atropine; Biological Assay; Brain; Chemoreceptor Cells; Chlorisondamine; Chlorpromazine; Female; Histamine H1 Antagonists; Injections, Spinal; Male; Mice; Nicotine; Parasympatholytics; Seizures; Sympatholytics | 1971 |
Experimental evidence for imipramine like activity of fenfluramine.
Topics: Animals; Avoidance Learning; Blepharoptosis; Blood Pressure; Body Temperature; Cats; Columbidae; Drug Antagonism; Drug Synergism; Electroshock; Female; Fenfluramine; Histamine H1 Antagonists; Hypothermia; Imipramine; Male; Mice; Nicotine; Nictitating Membrane; Rabbits; Rats; Reserpine; Respiration; Seizures; Tetrabenazine; Tremor; Tremorine; Vomiting; Yohimbine | 1970 |
Partly reduced biphenyls as central nervous system agents. 2. cis- and trans-4-Arylcyclohexylamines.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Seizures; Structure-Activity Relationship | 1972 |
Partly reduced biphenyls as central nervous system agents. 1. 4-Arylcyclohex-3-enylamines.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Carbon Isotopes; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Motor Activity; Myocardium; Nicotine; Norepinephrine; Seizures; Serotonin; Spleen; Structure-Activity Relationship; Tritium | 1972 |
Central nervous system agents. 4. Analogs of 3-amino-2-phenylpropiophenone.
Topics: Amines; Animals; Appetite; Behavior, Animal; Central Nervous System; Electroshock; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Propiophenones; Seizures; Structure-Activity Relationship | 1972 |
Brain development in offspring of rats treated with nicotine during pregnancy.
Topics: Animals; Animals, Newborn; Brain; Electrophysiology; Electroshock; Female; Maternal-Fetal Exchange; Nicotine; Organ Size; Pregnancy; Rats; Seizures | 1973 |
A study of structure-activity relationships of a series of diphenylaminopropanols by factor analysis.
Topics: Amino Alcohols; Animals; Behavior, Animal; Chemical Phenomena; Chemistry, Physical; Electroshock; Factor Analysis, Statistical; Isomerases; Mice; Nicotine; Pupil; Seizures; Structure-Activity Relationship; Thiosemicarbazones | 1973 |
Central cholinomimetic actions of 3, 3-dimethyl-1-butanol carbamate.
Topics: Acetylcholine; Animals; Atropine; Brain; Carbamates; Carbon Isotopes; Dose-Response Relationship, Drug; Drug Interactions; Hydrolysis; In Vitro Techniques; Kinetics; Lethal Dose 50; Mice; Mice, Inbred ICR; Nerve Endings; Nicotine; Parasympathomimetics; Physostigmine; Rats; Rats, Inbred Strains; Seizures; Time Factors | 1973 |
Partly reduced biphenyls as cetral nervous system agents. 3. Cis- and trans-4-aryl-4-methoxycyclohexylamines.
Topics: Animals; Behavior, Animal; Biphenyl Compounds; Carbon Radioisotopes; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Male; Methyl Ethers; Mice; Mice, Inbred Strains; Motor Activity; Myocardium; Nicotine; Norepinephrine; Seizures; Serotonin; Spleen; Stereoisomerism; Tritium | 1973 |
Neuropharmacological study of prostaglandin (PG)F2a.
Topics: Analgesia; Animals; Body Temperature; Cerebral Ventricles; Escape Reaction; Injections; Motor Activity; Nicotine; Pentobarbital; Perphenazine; Prostaglandins; Seizures; Sleep; Tremorine | 1973 |
Differentiation between effects of nicotine and DMPP by amantadine.
Topics: Acetylcholine; Amantadine; Animals; Blood Pressure; Cats; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Ganglia, Autonomic; Male; Nicotine; Nictitating Membrane; Oxotremorine; Piperazines; Seizures | 1973 |
Antin ociceptive activity of nicotine.
Topics: Acetates; Analgesia; Animals; Dimethylphenylpiperazinium Iodide; Drug Tolerance; Injections, Intraperitoneal; Mecamylamine; Methods; Mice; Nicotine; Oxotremorine; Pain; Physostigmine; Rats; Reaction Time; Seizures; Tremorine | 1973 |
[The effects of sulpiride on the central nervous system].
Topics: Amphetamine; Analgesia; Animals; Atropine; Chlorpromazine; Male; Mescaline; Mice; Morphine; Nicotine; Pyrrolidines; Rabbits; Rats; Seizures; Serotonin; Serotonin Antagonists; Shock; Statistics as Topic; Sulfonic Acids; Tranquilizing Agents; Tremor; Tremorine; Tryptamines | 1969 |
[Prevention of certain acute and chronic effects of nicotine by N-acetylhydroxyproline].
Topics: Animals; Cerebral Cortex; Electroencephalography; Female; Humans; Hydroxyproline; Hypertension; Male; Nicotine; Rabbits; Seizures; Smoking | 1971 |
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
Topics: Alkaloids; Animals; Antiparkinson Agents; Atropine; Benztropine; Body Temperature; Central Nervous System; Dibenzazepines; Drug Antagonism; Indoles; Male; Methylamines; Mice; Nicotine; Oxotremorine; Parasympatholytics; Procyclidine; Pupil; Pyridines; Seizures; Tremor; Trihexyphenidyl | 1972 |
A new 2,6-difluorobenzodiazepinone.
Topics: Animals; Behavior, Animal; Benzazepines; Drug Synergism; Electroshock; Ethanol; Fluorine; Ketones; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Strychnine; Thiosemicarbazones | 1972 |
Central nervous system depressants. 9. Benzodiazepine sulfonamides.
Topics: Animals; Benzazepines; Benzodiazepinones; Central Nervous System; Depression, Chemical; Drug Synergism; Electroshock; Ethanol; Lethal Dose 50; Male; Motor Activity; Nicotine; Seizures; Sulfonamides | 1971 |
The contents of DOPA and catecholamines in several rat tissues and nicotine-induced convulsions.
Topics: Adrenal Glands; Animals; Brain Chemistry; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Epinephrine; Liver; Male; Mice; Monoamine Oxidase; Myocardium; Nicotine; Norepinephrine; Rats; Seizures | 1966 |
Effect of reserpine on brain levels of 14C-nicotine in relation to nicotine-induced convulsions.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorpromazine; Dihydroxyphenylalanine; Injections, Intraperitoneal; Liver; Male; Mice; Nicotine; Phenobarbital; Reserpine; Seizures | 1967 |
A simple method to measure central antinocotinic activity.
Topics: Animals; Atropine; Brain; Female; Infusions, Parenteral; Injections; Male; Methods; Mice; Nicotine; Phenobarbital; Phenytoin; Seizures | 1969 |
Pyrrolo[3,2,1-jk][1,4]benzodiazepines and pyrrolo[1,2,3-ef][1,5]benzodiazepines which have central nervous system activity.
Topics: Animals; Behavior, Animal; Benzazepines; Central Nervous System; Chemical Phenomena; Chemistry; Diazepam; Male; Mice; Muscle Contraction; Nicotine; Pyrroles; Reflex; Seizures | 1970 |
[Effect of nicotine on the development of audiogenic convulsions in animals of various ages].
Topics: Age Factors; Animals; Guinea Pigs; Injections, Intraperitoneal; Mice; Nicotine; Rats; Seizures; Sound; Species Specificity | 1970 |
[2-ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine, a new psychotropic compound].
Topics: Aggression; Alcohols; Animals; Behavior, Animal; Central Nervous System; Chemistry, Pharmaceutical; Cricetinae; Depression, Chemical; Drug Synergism; Fear; Hexobarbital; Humans; Magnetic Resonance Spectroscopy; Mice; Motor Activity; Nicotine; Oxazines; Psychopharmacology; Rats; Seizures; Spectrum Analysis; Stimulation, Chemical; Tranquilizing Agents | 1970 |
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine | 1967 |
Tetraethylammonium chloride as an antidote for certain insecticides in mice.
Topics: Animals; Antidotes; Atropine; Carbamates; Insecticides; Mice; Nicotine; Parathion; Seizures; Tetraethylammonium Compounds | 1968 |
The central nervous effects of bis-(4-aminophenyl)-alkyl derivatives.
Topics: Animals; Barbiturates; Blood-Brain Barrier; Brain; Chickens; Drug Synergism; Electroencephalography; Guinea Pigs; Kidney; Liver; Mice; Nicotine; Norepinephrine; Pentylenetetrazole; Propylamines; Rats; Seizures; Solubility | 1968 |
[vidence for a muscarinic inhibitory mechanism in the cerebral cortex].
Topics: Acetylcholine; Animals; Atropine; Cats; Cerebral Cortex; Drug Antagonism; Electric Stimulation; Electrophysiology; Female; Male; Mecamylamine; Nicotine; Nicotinic Acids; Parasympathomimetics; Physostigmine; Pilocarpine; Pyrrolidines; Scopolamine; Seizures; Tremorine | 1969 |
Some pharmacological properties of 4H-3-methylcarboxamide 1,3-benzoxazine-2-one (FI 6654).
Topics: Acetylcholine; Animals; Antidepressive Agents; Arousal; Atropine; Barium; Duodenum; Electroencephalography; Guinea Pigs; Histamine; Ileum; Imipramine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nicotine; Oxazines; Papaverine; Physostigmine; Rabbits; Rats; Seizures; Serotonin | 1969 |
Action of topically applied atropine, eserine, acetylcholine and nicotine on cortical epilepsy in the rabbit.
Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Nicotine; Physostigmine; Rabbits; Seizures | 1969 |
Pharmacology of diphenylalkyl derivatives. II. Pharmacology of beta,beta-bis-(4-aminophenyl)-propionitrile.
Topics: Aminopropionitrile; Animals; Anticonvulsants; Blood Circulation; Blood Pressure; Cats; Electroshock; Mice; Nicotine; Nitriles; Rats; Reflex; Seizures; Strychnine | 1966 |