Page last updated: 2024-08-26

nicotine and Absence Seizure

nicotine has been researched along with Absence Seizure in 163 studies

Research

Studies (163)

TimeframeStudies, this research(%)All Research%
pre-199079 (48.47)18.7374
1990's20 (12.27)18.2507
2000's35 (21.47)29.6817
2010's21 (12.88)24.3611
2020's8 (4.91)2.80

Authors

AuthorsStudies
Amadeo, A; Becchetti, A; Coatti, A; Colombo, G; Madaschi, L; Meneghini, S; Milani, N; Modena, D1
Funaro, MC; Khan, W; Moeller, JJ; Narrett, JA1
Benowitz, NL1
Faulcon, LM; Limpert, J; Murphy, I; Rudy, S; Wang, B1
Carson, RP; Kozek, LK; Wharton, JD1
Fang, ZT; Shao, XM1
Beno, S; Gilley, M1
Baker, DL; Deats, S; DeMichele, G; Dymond, R; O'Brien, M; Pagán, OR1
Cyranoski, D1
Chellian, R; Pandy, V1
Zolot, J1
Aroni, S; Carta, G; De Montis, MG; Lecca, S; Marrosu, F; Melis, M; Muntoni, AL; Murru, E; Pillolla, G; Pistis, M; Puligheddu, M; Scheggi, S1
Do, SH; Hur, W; Lim, YJ; Yoon, HJ; Zuo, Z1
Bach, D; Baker, D; Deats, S; Montgomery, E; Pagán, OR1
Fritz, K; Holoyda, B; Xiong, GL1
Berg, DK; Cao, SX; Chen, XJ; Chen, Z; Duan, S; He, HY; Li, XM; Shen, CJ; Sun, P; Wang, XD; Yang, CH; Zhang, Y1
Bao, J; Han, X; Li, X; Liu, H; Liu, Y; Thakur, M; Ye, A1
Bespalov, AY; Dravolina, OA; Dumpis, MA; Litasova, EV; Nikolaev, DN; Piotrovskiy, LB; Yakovleva, EE1
Chakrabarti, A; Medhi, B; Sahai, AK; Sood, N1
Efremov, OM; Gmiro, VE; Serdyuk, SE1
Funakoshi, T; Kobayashi, S; Ohashi, S; Tanaka, T1
Rehni, AK; Singh, TG1
Maresova, D; Pokorny, J; Riljak, V1
Desaer, C; Ramakrishnan, L1
Chakrabarti, A; Hota, D; Sahai, AK; Sood, N1
Benavidez, JM; Blednov, YA; Harris, RA; Homanics, GE1
Amador-Arjona, A; Armengol, L; Cabrera, R; Dierssen, M; Estivill, X; Fernández-Montes, RD; Gallego, X; Gratacòs, M; Maldonado, R; Marks, MJ; Molas, S; Murtra, P; Pumarola, M; Robles, N; Sabrià, J1
Ahamehe, M; Arzi, A; Sarahroodi, S1
Bach, D; Baker, D; Deats, S; Kotturu, D; Montgomery, E; Pagán, OR; Raffa, RB; Randolph, C; Rawls, S; Tallarida, C; Tenaglia, M; Wilk, G1
Gholami, M; Hajizadeh-Moghaddam, A; Roshan-Milani, S; Saboory, E; Zare, S1
Cohen, BN; Fonck, C; Grady, SR; Laverty, DC; Lester, HA; Lindstrom, JM; Marks, MJ; McIntosh, JM; McKinney, S; O'Neill, HC; Patzlaff, NE1
Aubin, HJ1
Finn, DA; Mark, GP1
Danysz, W; Löscher, W; Parsons, CG; Potschka, H; Wlaź, P1
Collins, AC; Damaj, MI; Deshpande, P; Fonck, C; Labarca, C; Lester, HA; Marks, MJ; Nashmi, R; Riedel, A; Schwarz, J1
Beaudet, A; Broide, RS; De Biasi, M; Orr-Urtreger, A; Paylor, R; Salas, R1
Bontempi, B; Lloyd, GK; Menzaghi, F; Risbrough, VB; Whelan, KT1
BOVET, D; LONGO, VG1
LAURENCE, DR; STACEY, RS2
GOKHALE, SD; GULATI, OD1
MICHAELSON, SM; ORCUTT, JA; PRYTHERCH, JP1
YAMAMOTO, I1
NAGAI, K1
VARDAPETIAN, GA1
ILIUCHENOK, RIu; OSTROVSKAIA, RU; VINNITSKII, IM1
CHUBB, FL; HAJDU, A; KOMLOSSY, J; LEE, CF; MCCOLL, JD1
FUJIWARA, M; SHIMAMOTO, K; YAMAWAKI, T1
ZEIMAL, EV2
OTORI, K1
Balogh, S; Collins, AC; Damaj, MI; Fonck, C; Labarca, C; Lester, HA; McKinney, S; Owens, J; Tapper, AR; Wehner, JM1
Beaudet, AL; Kedmi, M; Orr-Urtreger, A1
Bahçekapili, N; Diler, AS; Uzüm, G; Ziylan, YZ1
Bassetto, L; Cook, KD; De Biasi, M; Salas, R1
Bastlund, JF; Berry, D; Watson, WP1
Martin-Garcia, E; Pallares, M1
Brodtkorb, E; Picard, F1
Abraham, P; Damaj, MI; Ivy Carroll, F; Ma, W; Martin, BR; Navarro, HA; Wolckenhauer, SA1
Boulter, J; Glykys, J; Klaassen, A; Labarca, C; Maguire, J; Mody, I1
Bing, G; Chae, JS; Cheon, MA; Jung, ME; Kim, HC; Kim, WK; Ko, KH; Nah, SY; Shin, EJ; Wie, MB1
Crouch, EL; Iacob, E; Jenkins, PM; Lautner, MA; Mexal, S; Stitzel, JA1
Kedmi, M; Orr-Urtreger, A1
Belluzzi, JD; Gee, KW; Hogenkamp, DJ; Leslie, FM; Li, WY; Tran, MB; Whittemore, ER; Yoshimura, RF1
Chan, MH; Chen, HH; Chien, TH; Tang, YC1
Levin, ED; Timofeeva, OA1
Chow, SC; Johnston, GA; Skerritt, JH1
Iizuka, H; Kawaguchi, T; Shimada, A; Yanagita, T1
Collins, AC; Marks, MJ; Miner, LL4
Chaturvedi, AK1
Caulfield, MP; Higgins, GA1
Bonnaud, B; Charveron, M; Cousse, H; Lauressergues, H; Morre, M; Mouzin, G; Stenger, A1
Brioni, JD; Buckley, MJ; Decker, MW; Giardina, WJ; Kang, CH; Kim, DJ; Radek, RJ; Raszkiewicz, JL; Sullivan, JP; Wasicak, JT1
Kita, T; Nakashima, T; Okamoto, M; Okuda, H; Tanaka, T2
Mimaki, Y; Sashida, Y; Yamada, K1
Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Saraswati, M1
Borlongan, CV; Sanberg, PR; Shytle, RD1
Cui, WY; Liu, CG; Wang, H1
Abood, LG; Journet, M; Kende, AS; Rubin, L; Sharma, VK; Sheu, SS; Wang, DX1
Cui, WY; Gao, ZG; Liu, BY; Liu, CG; Wang, L1
Blanchette, JM; Collins, AC; Stitzel, JA1
Cui, WY; Fan, QH; Gao, ZG; Li, LJ; Liu, BY; Liu, CG1
Lu, XQ; Wang, H; Zhang, YF1
Carroll, FI; Damaj, MI; Martin, BR; Slemmer, JE1
Diler, AS; Uzüm, G; Ziylan, YZ1
Damaj, MI; Dukat, M; Glassco, W; Martin, BR1
Collins, AC; Jimenez, M; Marks, MJ; Stitzel, JA; Tritto, T1
Boyce, S; Hill, RG; Rupniak, NMJ; Russell, MGN; Shepheard, SL; Webb, JK1
Collins, AC; Jimenez, M; Lu, Y; Stitzel, JA; Tritto, T1
Damaj, MI1
Carlson, J; Ellison, G; Noguchi, K1
Brown, S; Ennifar, S; Fattom, A; Hieda, Y; Keyler, DE; Pentel, PR; Tuncok, Y1
Alves, C; Barbosa, E; Gonçalves, FR; Lopes, L; Nunes, JP1
Manresa, JJ; Newman, MB; Sanberg, PR; Shytle, RD1
Bassetto, L; Broide, R; De Biasi, M; Franceschini, D; Gotti, C; Paylor, R; Salas, R1
Broide, RS; Dani, JA; De Biasi, M; Ji, D; Patrick, JW; Paylor, R; Salas, R1
Gil, Z; Harmelin, A; Kedmi, M; Orr-Urtreger, A; Sack, RA1
Dawson, R; de Fiebre, CM; de Fiebre, NC1
Aceto, MD1
Chidester, C; Duchamp, DJ; Gall, M; Lahti, RA; Rudzik, AD; Scahill, T1
Alpern, HP; Greer, CA1
Connor, J; Connor, T; Marshall, PB; Reid, A; Turnbull, MJ1
Schlesinger, K; Tepper, JM; Wilson, JR1
Abood, LG; Booth, H; Lowy, K; Tometsko, A1
Emmert, ED; Graham, BE; Lednicer, D; Rudzik, AD1
Elegbe, RA; Oyebola, DD1
Kamdar, BV; Moffett, RB; Von Voigtlander, PF1
Barry, H; Sofia, RD; Solomon, TA1
Kita, T; Nakashima, T; Okamoto, M; Okuda, H1
Bardgett, ME; Gray, BC; Miller, JW1
Abood, LG; Hashmi, M; Saraswati, M1
Collins, AC; Freund, RK; Luntz-Leybman, V1
Janz, T; Singer, J1
Collins, AC; Miner, LL3
Gothóni, P; Ikola, W1
Beleslin, DB; Krstić, SK1
Alvarado-Garcia, R; Lee, MA; Witkin, JM; Witkin, KM1
Ishikawa, T; Nagata, M; Osumi, Y1
Gogolák, G; Liebeswar, G; Stumpf, C1
Izquierdo, I; Nasello, AG1
Zejmal, EV1
György, L; Molnár, J; Nádor, K; Pfeifer, KA1
Inoki, R; Otori, K; Yamamoto, I1
Beckett, AH; Hunter, WH; Kourounakis, P1
Aceto, MD; Bentley, HC; Dembinski, JR1
Dhasmana, KM; Dixit, KS; Kohli, RP; Saxena, RC2
Dhawan, BN; Singh, HK; Srimal, RC1
Izquierdo, I1
Lampe, KF1
Emmert, DE; Lahti, R; Lednicer, D; Rudzik, AD3
Hester, JB; Moffett, RB1
Hudson, DB; Meisami, E; Timiras, PS1
Weiner, ML; Weiner, PH1
Chiou, CY; Wecker, L1
Bhandari, DS; Singh, KP1
Claassen, V; Davies, JE; Dhasmana, KM; Spilker, BA1
Bite, A; Dóda, M; György, L; Phan, DV1
Laville, C; Margarit, J1
Beaumont, JL; Buxtorf, JC; Cahn, J; Denis, JC; Jacotot, B; Patois, E; Rambaud, J1
McCulloch, JA; Ursillo, RC1
Hester, JB; Lemke, TL; Rudzik, AD1
Moffett, RB; Rudzik, AD1
Inoki, R; Nagai, K; Yamamoto, I1
Inoki, R; Iwatsubo, K; Tamari, Y; Yamamoto, I1
Hester, JB; Rudzik, AD; Veldkamp, W1
Zakhariia, EA; Zapadniuk, VI1
Hoffmann, I; Kuch, H; Schmitt, K; Seidl, G1
de Carolis, AS; Longo, VG1
Andrews, TL; Miskus, RP1
Leszkovszky, GP; Sebestyén, G; Takács, K; Tardos, L1
Krip, G; Pinsky, C; Vazquez, AJ1
Bertazzoli, C; Bonsignori, A; Chieli, T; Pegrassi, L; Suchowsky, GK1
Bernard, PJ; De Schaepdryver, AF; Delaunois, AL; Piette, Y1
Lendvai, J; Leszkovszky, G; Takács, K; Tardos, L1

Reviews

6 review(s) available for nicotine and Absence Seizure

ArticleYear
Vaping implications for children and youth.
    Current opinion in pediatrics, 2020, Volume: 32, Issue:3

    Topics: Adolescent; Burns; Child; Electronic Nicotine Delivery Systems; Humans; Lung Injury; Nicotine; Seizures; Students; Vaping

2020
Tolerability and safety of sustained-release bupropion in the management of smoking cessation.
    Drugs, 2002, Volume: 62 Suppl 2

    Topics: Bupropion; Clinical Trials as Topic; Consumer Product Safety; Delayed-Action Preparations; Dopamine Uptake Inhibitors; Humans; Nicotine; Seizures; Sleep Initiation and Maintenance Disorders; Smoking Cessation; Tobacco Use Disorder; Xerostomia

2002
Hypersensitive knockin mouse strains identify receptors and pathways for nicotine action.
    Current opinion in drug discovery & development, 2003, Volume: 6, Issue:5

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Body Temperature; Brain; Mice; Mice, Mutant Strains; Models, Animal; Nicotine; Nicotinic Agonists; Point Mutation; Receptors, Nicotinic; Seizures

2003
Pharmacology of the brain: the hippocampus, learning and seizures.
    Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 1972, Volume: 16

    Topics: Acetylcholine; Aminobutyrates; Amphetamine; Animals; Anura; Brain Chemistry; Dronabinol; Electric Stimulation; Evoked Potentials; Glutamates; Hippocampus; Learning; Nicotine; Norepinephrine; Osmolar Concentration; Phenytoin; Physostigmine; Potassium; Rats; RNA; Seizures; Serotonin; Stimulation, Chemical; Synaptic Transmission

1972
Hippocampal physiology: experiments on regulation of its electrical activity, on the mechanism of seizures, and on a hypothesis of learning.
    Behavioral biology, 1972, Volume: 7, Issue:5

    Topics: Amphetamine; Animals; Electric Stimulation; Electroencephalography; Electrophysiology; Evoked Potentials; Hippocampus; Ions; Learning; Mice; Neurons; Nicotine; Physostigmine; Potassium; Protein Biosynthesis; Rabbits; Rats; RNA; Seizures

1972
Systemic plant poisoning in children.
    Pediatrics, 1974, Volume: 54, Issue:3

    Topics: Albumins; Alkaloids; Atropine; Atropine Derivatives; Basidiomycota; Charcoal; Child; Digitalis; Gastroenteritis; Humans; Mouth; Mushroom Poisoning; Nicotine; Phenytoin; Physostigmine; Plant Poisoning; Plants; Plants, Medicinal; Plants, Toxic; Poisons; Potassium Chloride; Renal Dialysis; Seizures; Toxins, Biological; Vomiting; Water-Electrolyte Balance

1974

Other Studies

157 other study(ies) available for nicotine and Absence Seizure

ArticleYear
The β2
    Progress in neurobiology, 2022, Volume: 214

    Topics: Acetylcholine; Animals; Epilepsy; Humans; Mice; Mice, Transgenic; Neurons; Nicotine; Prefrontal Cortex; Receptors, Nicotinic; Seizures; Sleep; Somatostatin

2022
How do smoking, vaping, and nicotine affect people with epilepsy and seizures? A scoping review protocol.
    PloS one, 2023, Volume: 18, Issue:7

    Topics: Epilepsy; Humans; Nicotine; Research Design; Review Literature as Topic; Seizures; Smoking; Smoking Cessation; Systematic Reviews as Topic; Tobacco Smoking; Tobacco Use Cessation Devices; Vaping

2023
Seizures After Vaping Nicotine in Youth: A Canary or a Red Herring?
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2020, Volume: 66, Issue:1

    Topics: Adolescent; Electronic Nicotine Delivery Systems; Humans; Nicotine; Seizures; Vaping; Young Adult

2020
Adverse Experience Reports of Seizures in Youth and Young Adult Electronic Nicotine Delivery Systems Users.
    The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2020, Volume: 66, Issue:1

    Topics: Adolescent; Adult; Cannabis; Electronic Nicotine Delivery Systems; Humans; Nicotine; Seizures; Tobacco Products; Vaping; Young Adult

2020
Increased Seizure Frequency Temporally Related to Vaping: Where There's Vapor, There's Seizures?
    Pediatric neurology, 2020, Volume: 104

    Topics: Adolescent; Epilepsy, Generalized; Female; Humans; Nicotine; Nicotinic Agonists; Seizures; Vaping

2020
Severe Acute Toxicity of Inhaled Nicotine and e-Cigarettes: Seizures and Cardiac Arrhythmia.
    Chest, 2020, Volume: 157, Issue:3

    Topics: Administration, Inhalation; alpha7 Nicotinic Acetylcholine Receptor; Amygdala; Animals; Arrhythmias, Cardiac; Autonomic Fibers, Preganglionic; Electronic Nicotine Delivery Systems; Humans; Medulla Oblongata; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Respiratory Center; Respiratory Insufficiency; Seizures; Vaping

2020
Measuring functional brain recovery in regenerating planarians by assessing the behavioral response to the cholinergic compound cytisine.
    The International journal of developmental biology, 2020, Volume: 64, Issue:7-8-9

    Topics: Alkaloids; Anesthetics, Local; Animals; Azocines; Brain; Carbachol; Cholinergic Agents; Cocaine; Cotinine; Dose-Response Relationship, Drug; Ethanol; Nicotine; Planarians; Quinolizines; Regeneration; Seizures

2020
China expands surveillance of sewage to police illegal drug use.
    Nature, 2018, Volume: 559, Issue:7714

    Topics: Caffeine; China; Cities; Humans; Illicit Drugs; Nicotine; Police; Seizures; Sewage; Wastewater

2018
Protective effect of α-asarone against nicotine-induced seizures in mice, but not by its interaction with nicotinic acetylcholine receptors.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 108

    Topics: Allylbenzene Derivatives; Animals; Anisoles; Anticonvulsants; Dose-Response Relationship, Drug; Locomotion; Male; Mice; Mice, Inbred ICR; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Seizures

2018
Some Young Adult E-Cigarette Users Report Seizures.
    The American journal of nursing, 2019, Volume: 119, Issue:7

    Topics: Electronic Nicotine Delivery Systems; Female; Humans; Male; Nicotine; Seizures; Smoking; Young Adult

2019
PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Animals; Anticonvulsants; Drug Evaluation, Preclinical; Epilepsy, Frontal Lobe; Fenofibrate; Frontal Lobe; Inhibitory Postsynaptic Potentials; Male; Membrane Potentials; Mice; Nicotine; Patch-Clamp Techniques; Phosphorylation; PPAR alpha; Pyramidal Cells; Pyrimidines; Rats; Receptors, Nicotinic; Seizures

2013
Nicotine decreases the activity of glutamate transporter type 3.
    Toxicology letters, 2014, Feb-10, Volume: 225, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Activators; Excitatory Amino Acid Transporter 3; Female; Glutamic Acid; Membrane Potentials; Nicotine; Nicotinic Agonists; Oocytes; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Kinase Inhibitors; Rats; Seizures; Time Factors; Xenopus laevis

2014
Evidence of Nicotine-Induced, Curare-Insensitive, Behavior in Planarians.
    Neurochemical research, 2015, Volume: 40, Issue:10

    Topics: Animals; Behavior, Animal; Curare; Movement; Nicotine; Planarians; Seizures

2015
A case of nicotine overdose-induced seizure on an inpatient psychiatric unit.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2016, Volume: 28, Issue:1

    Topics: Adult; Drug Overdose; Female; Humans; Nicotine; Psychotic Disorders; Seizures; Tobacco Use Cessation Devices

2016
Loss of MeCP2 in cholinergic neurons causes part of RTT-like phenotypes via α7 receptor in hippocampus.
    Cell research, 2016, Volume: 26, Issue:6

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzamides; Bridged Bicyclo Compounds; Caudate Nucleus; Cholinergic Neurons; Disease Susceptibility; Gene Deletion; Hippocampus; Male; Methyl-CpG-Binding Protein 2; Mice, Inbred C57BL; Mice, Knockout; Models, Biological; Nicotine; Phenotype; Prosencephalon; Rett Syndrome; Seizures; Signal Transduction

2016
Nicotine increases eclampsia-like seizure threshold and attenuates microglial activity in rat hippocampus through the α7 nicotinic acetylcholine receptor.
    Brain research, 2016, 07-01, Volume: 1642

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; Blood Pressure; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Drug Evaluation, Preclinical; Eclampsia; Female; Lipopolysaccharides; Microglia; Neuroimmunomodulation; Neurons; Nicotine; Nicotinic Agonists; Pentylenetetrazole; Pregnancy; Pregnancy Outcome; Random Allocation; Rats, Sprague-Dawley; Seizures

2016
Enhanced brain penetration of hexamethonium in complexes with derivatives of fullerene C60.
    Doklady. Biochemistry and biophysics, 2016, Volume: 468, Issue:1

    Topics: Aminocaproates; Animals; Anticonvulsants; Brain; Dose-Response Relationship, Drug; Fullerenes; Hexamethonium Compounds; Locomotion; Male; Mice; Nicotine; Nicotinic Antagonists; Rats, Wistar; Seizures

2016
Dose-finding study with nicotine as a proconvulsant agent in PTZ-induced seizure model in mice.
    Journal of biomedical science, 2008, Volume: 15, Issue:6

    Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fructose; Ganglionic Stimulants; Male; Mice; Nicotine; Pentylenetetrazole; Seizures; Topiramate; Valproic Acid

2008
Peripheral and central routes of administration of quaternary ammonium compound IEM-1460 are equally potent in reducing the severity of nicotine-induced seizures in mice.
    Bulletin of experimental biology and medicine, 2008, Volume: 146, Issue:1

    Topics: Adamantane; Animals; Biguanides; Male; Mice; Nicotine; Receptors, AMPA; Receptors, Nicotinic; Seizures

2008
YB-1 binds to GluR2 mRNA and CaM1 mRNA in the brain and regulates their translational levels in an activity-dependent manner.
    Cellular and molecular neurobiology, 2010, Volume: 30, Issue:7

    Topics: Adrenergic alpha-Agonists; Animals; Brain; Calmodulin; Carbachol; Cell Line; Cholinergic Agonists; Excitatory Amino Acid Agonists; Gene Expression Regulation; Kainic Acid; Mice; Nicotine; Nicotinic Agonists; Norepinephrine; Protein Isoforms; Rats; Receptors, AMPA; Recombinant Fusion Proteins; RNA, Messenger; RNA, Small Interfering; Seizures; Transcription Factors; Y-Box-Binding Protein 1

2010
Levamisole-induced reduction in seizure threshold: a possible role of nicotinic acetylcholine receptor-mediated pathway.
    Naunyn-Schmiedeberg's archives of pharmacology, 2010, Volume: 382, Issue:3

    Topics: Animals; Antinematodal Agents; Behavior, Animal; Dose-Response Relationship, Drug; Drug Synergism; Levamisole; Male; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Receptors, Nicotinic; Seizures

2010
Nicotine effects on rat seizures susceptibility and hippocampal neuronal degeneration.
    Neuro endocrinology letters, 2010, Volume: 31, Issue:6

    Topics: Animals; Cerebral Cortex; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Electrodes, Implanted; Electrophysiology; Evoked Potentials; Hippocampus; Injections, Intraperitoneal; Motor Cortex; Nerve Degeneration; Neurons; Nicotine; Nicotinic Agonists; Random Allocation; Rats; Rats, Wistar; Seizures

2010
Carbamazepine inhibits distinct chemoconvulsant-induced seizure-like activity in Dugesia tigrina.
    Pharmacology, biochemistry, and behavior, 2011, Volume: 99, Issue:4

    Topics: Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Convulsants; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; GABA Antagonists; N-Methylaspartate; Nicotine; Nicotinic Agonists; Oxcarbazepine; Picrotoxin; Planarians; Seizures; Structure-Activity Relationship

2011
Nicotine reversal of anticonvulsant action of topiramate in kainic acid-induced seizure model in mice.
    Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2011, Volume: 13, Issue:11

    Topics: Animals; Anticonvulsants; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Fructose; Humans; Kainic Acid; Lipid Peroxidation; Male; Mecamylamine; Mice; Nicotine; Nicotinic Antagonists; Receptors, Nicotinic; Seizures; Topiramate

2011
Behavioral characterization of knockin mice with mutations M287L and Q266I in the glycine receptor α1 subunit.
    The Journal of pharmacology and experimental therapeutics, 2012, Volume: 340, Issue:2

    Topics: 1-Butanol; Alcohol Drinking; Alcohol Withdrawal Seizures; Amino Acid Substitution; Animals; Behavior, Animal; Central Nervous System Depressants; Conditioning, Classical; Drug Synergism; Eating; Ethanol; Female; Food Preferences; Gene Knock-In Techniques; Male; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Motor Skills; Mutation; N-Methylaspartate; Nicotine; Pentylenetetrazole; Quinine; Receptors, Glycine; Reflex, Righting; Reflex, Startle; Rotarod Performance Test; Saccharin; Seizures; Sex Characteristics; Strychnine; Taste Perception

2012
Overexpression of the CHRNA5/A3/B4 genomic cluster in mice increases the sensitivity to nicotine and modifies its reinforcing effects.
    Amino acids, 2012, Volume: 43, Issue:2

    Topics: Analysis of Variance; Animals; Binding Sites; Cerebral Cortex; Cloning, Molecular; Corpus Striatum; Dose-Response Relationship, Drug; Female; Gene Expression; Genetic Engineering; Hippocampus; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Multigene Family; Nerve Tissue Proteins; Nicotine; Phenotype; Proto-Oncogene Proteins c-fos; Radionuclide Imaging; Receptors, Nicotinic; Seizures; Self Administration; Tobacco Use Disorder

2012
Effect of hydroalcoholic extract of Lavandula officinalis on nicotine-induced convulsion in mice.
    Pakistan journal of biological sciences : PJBS, 2011, Jun-01, Volume: 14, Issue:11

    Topics: Animals; Anticonvulsants; Dose-Response Relationship, Drug; Lavandula; Male; Mice; Nicotine; Nicotinic Agonists; Plant Extracts; Seizures

2011
Planarians in pharmacology: parthenolide is a specific behavioral antagonist of cocaine in the planarian Girardia tigrina.
    The International journal of developmental biology, 2012, Volume: 56, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Behavior, Animal; Cocaine; Dopamine Uptake Inhibitors; Excitatory Amino Acid Agonists; Methamphetamine; N-Methylaspartate; Nicotine; Nicotinic Agonists; Planarians; Regeneration; Seizures; Sesquiterpenes

2012
The effect of dorsal hippocampal administration of nicotinic and muscarinic cholinergic ligands on pentylenetetrazol-induced generalized seizures in rats.
    Epilepsy & behavior : E&B, 2012, Volume: 25, Issue:2

    Topics: Animals; Atropine; Hippocampus; Male; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Oxotremorine; Pentylenetetrazole; Rats; Rats, Wistar; Seizures

2012
Mice expressing the ADNFLE valine 287 leucine mutation of the Β2 nicotinic acetylcholine receptor subunit display increased sensitivity to acute nicotine administration and altered presynaptic nicotinic receptor function.
    Pharmacology, biochemistry, and behavior, 2013, Volume: 103, Issue:3

    Topics: Acetylcholine; Animals; Body Temperature; Central Nervous System Sensitization; Cerebral Cortex; Dopamine; Dystonia; gamma-Aminobutyric Acid; Gene Knock-In Techniques; Hippocampus; Male; Mice; Motor Activity; Mutation, Missense; Nicotine; Presynaptic Terminals; Radioligand Assay; Receptors, Nicotinic; Rubidium Radioisotopes; Seizures; Synaptosomes

2013
The relationship between hippocampal acetylcholine release and cholinergic convulsant sensitivity in withdrawal seizure-prone and withdrawal seizure-resistant selected mouse lines.
    Alcoholism, clinical and experimental research, 2002, Volume: 26, Issue:8

    Topics: Acetylcholine; Alcohol Withdrawal Seizures; Animals; Carbachol; Cholinergic Agents; Convulsants; Hippocampus; Male; Mice; Neostigmine; Nicotine; Seizures; Species Specificity

2002
Are neuronal nicotinic receptors a target for antiepileptic drug development? Studies in different seizure models in mice and rats.
    European journal of pharmacology, 2003, Apr-11, Volume: 466, Issue:1-2

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Electroshock; Female; Hippocampus; In Vitro Techniques; Injections, Subcutaneous; Kindling, Neurologic; Mice; Motor Activity; Nicotine; Nicotinic Antagonists; Patch-Clamp Techniques; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Seizures

2003
Increased sensitivity to agonist-induced seizures, straub tail, and hippocampal theta rhythm in knock-in mice carrying hypersensitive alpha 4 nicotinic receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Apr-01, Volume: 23, Issue:7

    Topics: Animals; Behavior, Animal; Brain; Electroencephalography; Female; Gene Dosage; Hippocampus; Male; Mice; Mice, Neurologic Mutants; Nicotine; Nicotinic Agonists; Phenotype; Receptors, Nicotinic; Seizures; Tail; Theta Rhythm

2003
The nicotinic acetylcholine receptor subunit alpha 5 mediates short-term effects of nicotine in vivo.
    Molecular pharmacology, 2003, Volume: 63, Issue:5

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Drosophila Proteins; Locomotion; Mice; Mice, Knockout; Mutation; Nicotine; Protein Subunits; Receptors, Nicotinic; Seizures

2003
Cognitive enhancing properties and tolerability of cholinergic agents in mice: a comparative study of nicotine, donepezil, and SIB-1553A, a subtype-selective ligand for nicotinic acetylcholine receptors.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2003, Volume: 28, Issue:7

    Topics: Age Factors; Animals; Attention; Behavior, Animal; Choice Behavior; Cholinesterase Inhibitors; Cognition; Discrimination Learning; Donepezil; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Indans; Lethal Dose 50; Male; Mecamylamine; Memory, Short-Term; Mice; Mice, Inbred C57BL; Motor Activity; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phenols; Piperidines; Psychomotor Performance; Pyrrolidines; Reaction Time; Receptors, Nicotinic; Scopolamine; Seizures

2003
[Electroencephalographic study on antagonism of anti-epileptic drugs to tremors produced by nicotine].
    Bollettino della Societa italiana di biologia sperimentale, 1952, Volume: 28, Issue:4

    Topics: Electroencephalography; Humans; Nicotine; Seizures; Tremor

1952
Mechanism of the prevention of nicotine convulsions by hexamethonium and by adrenaline blocking agents.
    British journal of pharmacology and chemotherapy, 1953, Volume: 8, Issue:1

    Topics: Adrenal Glands; Biomedical Research; Colorimetry; Epinephrine; Hexamethonium; Humans; Muscle Relaxants, Central; Nicotine; Norepinephrine; Seizures; Sympatholytics

1953
Nicotine convulsions and their modification by reserpine and chlorpromazine.
    Indian journal of physiology and pharmacology, 1962, Volume: 6

    Topics: Chlorpromazine; Nicotine; Reserpine; Seizures

1962
THE INHIBITION OF NICOTINE-INDUCED CONVULSIONS IN THE RAT.
    Archives internationales de pharmacodynamie et de therapie, 1963, Nov-01, Volume: 146

    Topics: Anesthetics; Anesthetics, Local; Anticonvulsants; Nicotine; Pharmacology; Phenobarbital; Procaine; Rats; Research; Seizures

1963
THIAMINE AS A NICOTINE ANTAGONIST.
    Japanese journal of pharmacology, 1963, Volume: 13

    Topics: Animals; Antimetabolites; Anura; Blood Pressure; Blood Pressure Determination; Bufonidae; Cats; Dogs; Ear, External; Guinea Pigs; Heart; Hyperglycemia; Intestine, Small; Intestines; Nicotine; Nictitating Membrane; Pharmacology; Rabbits; Research; Seizures; Thiamine; Toxicology

1963
[STUDIES ON NICOTINE. CHANGES IN CATECHLOAMINES IN RATS WITH NICOTINE-INDUCED CONVULSIONS].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1963, Nov-20, Volume: 59

    Topics: Adrenal Glands; Adrenalectomy; Brain; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Epinephrine; Heart; Monoamine Oxidase Inhibitors; Nicotine; Norepinephrine; Rats; Research; Seizures

1963
[THE BIOELECTRIC ACTIVITY OF THE CENTRAL AND SYMPATHETIC NERVOUS SYSTEMS IN CAMPHOR, NICOTINE AND PICROTOXIN-INDUCED SEIZURES].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1963, Volume: 49

    Topics: Autonomic Nervous System; Camphor; Electroencephalography; Ganglia; Ganglia, Autonomic; Hypothalamus; Nicotine; Pharmacology; Picrotoxin; Rabbits; Research; Seizures; Sympathetic Nervous System; Toxicology

1963
[THE EFFECT OF NANOPHYNE, PACHYCARPINE AND GANGLERONE ON THE ACTIVATING AND CONVULSIVE EFFECTS OF NICOTINE].
    Biulleten' eksperimental'noi biologii i meditsiny, 1963, Volume: 56

    Topics: Animals; Benzoates; Cats; Electroencephalography; Ganglionic Blockers; Lagomorpha; Nicotine; Pharmacology; Rabbits; Research; Seizures; Sparteine; Toxicology

1963
SYNTHESIS AND PHARMACOLOGICAL PROPERTIES OF PHENYL-SUBSTITUTED BIURETS.
    Journal of medicinal chemistry, 1963, Volume: 6

    Topics: Atropine; Biuret; Chemistry, Pharmaceutical; Gastric Juice; Meprobamate; Mice; Nicotine; Pentylenetetrazole; Peptic Ulcer; Pharmacology; Phenformin; Phenobarbital; Picrotoxin; Rats; Research; Seizures; Strychnine; Toxicology; Urea

1963
EFFECTS OF MONOAMINE RELEASERS ON THE TREMOR CONVULSIONS AND LETHAL EFFECTS OF NICOTINE IN MICE.
    Archives internationales de pharmacodynamie et de therapie, 1964, Sep-01, Volume: 151

    Topics: Alkaloids; Amines; Dopamine; Hypnotics and Sedatives; Methyldopa; Mice; Nicotine; Pharmacology; Rauwolfia; Research; Reserpine; Seizures; Tetrabenazine; Toxicology; Tremor

1964
[CENTRAL EFFECT OF SOME CHOLINERGIC SUBSTANCES FOLLOWING THEIR INTRAVENOUS ADMINISTRATION AND AFTER THEIR INTRODUCTION INTO THE LATERAL CEREBRAL VENTRICLE IN THE MOUSE].
    Doklady Akademii nauk SSSR, 1964, Apr-21, Volume: 155

    Topics: Acetylcholine; Administration, Intravenous; Animals; Cerebral Ventricles; Cholinergic Agents; Hexamethonium Compounds; Injections; Injections, Intravenous; Mice; Nicotine; Parasympathomimetics; Pharmacology; Research; Seizures

1964
[ON THE CHARACTERISTICS OF CENTRAL CHOLINE RECEPTORS SIMULATED BY NICOTINE].
    Doklady Akademii nauk SSSR, 1964, Jul-01, Volume: 157

    Topics: Animals; Cerebral Ventricles; Choline; Hexamethonium Compounds; Mice; Muscle Relaxants, Central; Nicotine; Pharmacology; Research; Seizures; Sensory Receptor Cells

1964
[PHARMACOLOGICAL STUDIES ON ANTAGONISTS TO NICOTINE-INDUCED CONVULSIONS AND DEATH].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1964, Nov-20, Volume: 60

    Topics: Anticonvulsants; Hypnotics and Sedatives; Mice; Nicotine; Pharmacology; Research; Seizures; Toxicology; Tranquilizing Agents

1964
The effect of methonium compounds on nicotine convulsions.
    British journal of pharmacology and chemotherapy, 1952, Volume: 7, Issue:1

    Topics: Bis-Trimethylammonium Compounds; Drug-Related Side Effects and Adverse Reactions; Epinephrine; Muscle Relaxants, Central; Nicotine; Seizures

1952
Mice lacking neuronal nicotinic acetylcholine receptor beta4-subunit and mice lacking both alpha5- and beta4-subunits are highly resistant to nicotine-induced seizures.
    Physiological genomics, 2004, Apr-13, Volume: 17, Issue:2

    Topics: Animals; Brain; Female; Gene Expression; Kinetics; Male; Mice; Mice, Knockout; Mice, Transgenic; Nicotine; Nicotinic Agonists; Protein Subunits; Receptors, Nicotinic; Seizures

2004
Tolerance to pentylentetrazol-induced convulsions and protection of cerebrovascular integrity by chronic nicotine.
    The International journal of neuroscience, 2004, Volume: 114, Issue:6

    Topics: Analysis of Variance; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Capillary Permeability; Cerebrovascular Circulation; Drug Administration Schedule; Drug Interactions; Drug Tolerance; Evans Blue; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pentylenetetrazole; Rats; Rats, Wistar; Seizures; Specific Gravity; Time Factors

2004
The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice.
    Neuropharmacology, 2004, Volume: 47, Issue:3

    Topics: Analysis of Variance; Animals; Dose-Response Relationship, Drug; Female; Gene Expression; In Situ Hybridization; Locomotion; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nicotine; Nicotinic Agonists; Protein Subunits; Receptors, Nicotinic; RNA, Messenger; Seizures; Sex Factors

2004
Pharmacological and histological characterisation of nicotine-kindled seizures in mice.
    Neuropharmacology, 2005, Volume: 48, Issue:7

    Topics: Animals; Brain Chemistry; Immunohistochemistry; Kindling, Neurologic; Male; Mice; Nicotine; Seizures

2005
Effects of intrahippocampal nicotine and neurosteroid administration on withdrawal in voluntary and chronic alcohol-drinking rats.
    Alcoholism, clinical and experimental research, 2005, Volume: 29, Issue:9

    Topics: Animals; Body Weight; Ethanol; Hippocampus; Male; Motor Activity; Nicotine; Pregnanolone; Pregnenolone; Rats; Rats, Wistar; Seizures; Substance Withdrawal Syndrome

2005
Tobacco habits modulate autosomal dominant nocturnal frontal lobe epilepsy.
    Epilepsy & behavior : E&B, 2006, Volume: 9, Issue:3

    Topics: Administration, Cutaneous; Adult; Aged; Anticonvulsants; Epilepsy, Frontal Lobe; Female; Humans; Male; Middle Aged; Mutation; Nicotine; Receptors, Nicotinic; Seizures; Sleep; Smoking

2006
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
    Bioorganic & medicinal chemistry, 2007, Jan-15, Volume: 15, Issue:2

    Topics: Aconitine; Analgesics; Animals; Anticonvulsants; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Data Interpretation, Statistical; In Vitro Techniques; Indicators and Reagents; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Pain Measurement; Pyridines; Rats; Reaction Time; Receptors, Nicotinic; Seizures

2007
Seizures and enhanced cortical GABAergic inhibition in two mouse models of human autosomal dominant nocturnal frontal lobe epilepsy.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Dec-12, Volume: 103, Issue:50

    Topics: Animals; Disease Models, Animal; Electrophysiology; Epilepsy, Frontal Lobe; gamma-Aminobutyric Acid; Humans; Kinetics; Mice; Mice, Transgenic; Nicotine; Patch-Clamp Techniques; Receptors, Nicotinic; Seizures

2006
Repeated intracerebroventricular infusion of nicotine prevents kainate-induced neurotoxicity by activating the alpha7 nicotinic acetylcholine receptor.
    Epilepsy research, 2007, Volume: 73, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Dihydro-beta-Erythroidine; DNA; Hippocampus; Injections, Intraventricular; Kainic Acid; Kindling, Neurologic; Male; Mecamylamine; Neuroprotective Agents; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Transcription Factor AP-1

2007
alpha7 nicotinic receptor gene promoter polymorphisms in inbred mice affect expression in a cell type-specific fashion.
    The Journal of biological chemistry, 2007, May-04, Volume: 282, Issue:18

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bungarotoxins; Gene Expression Regulation; Genotype; Humans; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Nicotinic Agonists; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Promoter Regions, Genetic; Receptors, Nicotinic; Seizures; Species Specificity

2007
Expression changes in mouse brains following nicotine-induced seizures: the modulation of transcription factor networks.
    Physiological genomics, 2007, Aug-20, Volume: 30, Issue:3

    Topics: Animals; Brain; Drug Resistance; Female; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Nicotine; Oligonucleotide Array Sequence Analysis; Receptors, Nicotinic; Seizures; Transcription Factors; Transcription, Genetic

2007
Negative allosteric modulation of nicotinic acetylcholine receptors blocks nicotine self-administration in rats.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 323, Issue:3

    Topics: Allosteric Site; Aniline Compounds; Animals; Cell Membrane; Dose-Response Relationship, Drug; Electrophysiology; Feeding Behavior; Ligands; Male; Mice; Motor Activity; Naphthalenes; Nicotine; Nicotinic Antagonists; Oocytes; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Self Administration; Tobacco Use Disorder; Xenopus laevis

2007
Toluene exposure during the brain growth spurt reduced behavioral responses to nicotine in young adult rats: a potential role for nicotinic acetylcholine receptors in fetal solvent syndrome.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 101, Issue:2

    Topics: Aging; Animals; Behavior, Animal; Blotting, Western; Body Temperature; Brain; Disease Models, Animal; Female; Male; Nicotine; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Seizures; Solvents; Toluene

2008
Idazoxan blocks the nicotine-induced reversal of the memory impairment caused by the NMDA glutamate receptor antagonist dizocilpine.
    Pharmacology, biochemistry, and behavior, 2008, Volume: 90, Issue:3

    Topics: Adrenergic alpha-Antagonists; Animals; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; Idazoxan; Maze Learning; Memory; Memory Disorders; Memory, Short-Term; Nicotine; Nicotinic Agonists; Norepinephrine; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures; Synaptic Transmission

2008
Interactions of the anticonvulsant carbamazepine with adenosine receptors. 2. Pharmacological studies.
    Epilepsia, 1983, Volume: 24, Issue:5

    Topics: Animals; Carbamazepine; Guinea Pigs; Ileum; Male; Mice; Mice, Inbred Strains; Nicotine; Purines; Receptors, Cell Surface; Receptors, Purinergic; Seizures; Theophylline

1983
[Pharmacodynamic effects of d-nicotine--Comparison with l-nicotine].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1984, Volume: 84, Issue:1

    Topics: Animals; Cardiovascular System; Conditioning, Operant; Electroencephalography; Gastrointestinal Motility; Macaca mulatta; Male; Mice; Mice, Inbred ICR; Motor Activity; Neuromuscular Junction; Nicotine; Rats; Seizures; Stereoisomerism

1984
Classical genetic analysis of nicotine-induced seizures and nicotinic receptors.
    The Journal of pharmacology and experimental therapeutics, 1984, Volume: 231, Issue:3

    Topics: Animals; Bungarotoxins; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Iodine Radioisotopes; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures; Species Specificity; Tritium

1984
Effects of mecamylamine, nicotine, atropine and physostigmine on the phencyclidine-induced behavioral toxicity.
    Pharmacology, biochemistry, and behavior, 1984, Volume: 20, Issue:4

    Topics: Animals; Atropine; Behavior, Animal; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Mice; Motor Activity; Nicotine; Phencyclidine; Physostigmine; Seizures

1984
Mediation of nicotine-induced convulsions by central nicotinic receptors of the 'C6' type.
    Neuropharmacology, 1983, Volume: 22, Issue:3

    Topics: Animals; Drug Synergism; Ganglionic Stimulants; Injections, Intraventricular; Male; Mice; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Seizures

1983
[Phenothiazine carboxamides that have anticholinergic properties].
    Bollettino chimico farmaceutico, 1980, Volume: 119, Issue:1

    Topics: Animals; Behavior, Animal; Convulsants; Dogs; Mice; Nicotine; Parasympatholytics; Pentylenetetrazole; Phenothiazines; Salivation; Seizures; Tears; Tremor; Trihexyphenidyl

1980
(S)-3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole (ABT 418): a novel cholinergic ligand with cognition-enhancing and anxiolytic activities: II. In vivo characterization.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:1

    Topics: Alzheimer Disease; Animals; Anti-Anxiety Agents; Anticonvulsants; Avoidance Learning; Behavior, Animal; Body Temperature; Brain; Cerebrovascular Circulation; Cognition; Electroencephalography; Isoxazoles; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Nociceptors; Pyrrolidines; Rats; Rats, Wistar; Receptors, Cholinergic; Seizures; Vomiting

1994
Effects of aging on acute toxicity of nicotine in rats.
    Pharmacology & toxicology, 1994, Volume: 75, Issue:1

    Topics: Aging; Animals; Brain; Corticosterone; Cytochrome P-450 Enzyme System; Dopamine; Injections, Intraperitoneal; Liver; Male; Nicotine; Oxidoreductases; Oxygenases; Rats; Rats, Wistar; Seizures

1994
Anticonvulsive effects of inhaling lavender oil vapour.
    Biological & pharmaceutical bulletin, 1994, Volume: 17, Issue:2

    Topics: Administration, Inhalation; Animals; Anticonvulsants; Lavandula; Male; Mice; Nicotine; Oils, Volatile; Pentylenetetrazole; Plant Extracts; Plant Oils; Seizures; Strychnine

1994
Affinity ligands and related agents for brain muscarinic and nicotinic cholinergic receptors.
    Biochemical pharmacology, 1993, May-25, Volume: 45, Issue:10

    Topics: Affinity Labels; Animals; Brain; Carbachol; Choline; Kinetics; Ligands; Mice; Naloxone; Nicotine; Oxotremorine; Procaine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Tritium

1993
Nicotine blocks kainic acid-induced wet dog shakes in rats.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 1995, Volume: 13, Issue:3

    Topics: Animals; Kainic Acid; Male; Nicotine; Rats; Rats, Sprague-Dawley; Seizures

1995
Regulatory effects of acutely repeated nicotine treatment towards central muscarinic receptors.
    Life sciences, 1996, Volume: 59, Issue:17

    Topics: Animals; Brain; Down-Regulation; Electroencephalography; Female; Male; Mice; Muscarinic Agonists; Nicotine; Rabbits; Rats; Rats, Wistar; Receptors, Muscarinic; Seizures

1996
[3H]benzylpempidine, a new radioligand for probing a putative channel site on nicotinic cholinergic receptors.
    Life sciences, 1997, Volume: 60, Issue:15

    Topics: Animals; Binding, Competitive; Brain; Calcium; Calcium Channels; Cattle; Cell Membrane; Ligands; Mecamylamine; Mice; Nicotine; Nicotinic Antagonists; Pempidine; Receptors, Nicotinic; Seizures

1997
Anticholinergic activity in mice and receptor-binding properties in rats of a series of synthetic tropane derivatives.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: Animals; Arecoline; Brain; Drug Antagonism; Female; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Stereoisomerism; Structure-Activity Relationship; Tremor; Tropanes

1997
Sensitivity to the seizure-inducing effects of nicotine is associated with strain-specific variants of the alpha 5 and alpha 7 nicotinic receptor subunit genes.
    The Journal of pharmacology and experimental therapeutics, 1998, Volume: 284, Issue:3

    Topics: Animals; Brain; Bungarotoxins; Genotype; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Polymorphism, Genetic; Receptors, Nicotinic; Seizures; Species Specificity

1998
Anti-nicotinic properties of anticholinergic antiparkinson drugs.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:11

    Topics: Animals; Antiparkinson Agents; Atropine; Brain; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Female; In Vitro Techniques; Male; Mecamylamine; Nicotine; Nicotinic Antagonists; Protein Binding; Rats; Seizures

1998
Modulation of phosphatidylinositol turnover on central nicotinic receptors.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:4

    Topics: Animals; Brain; Lithium Chloride; Male; Mice; Muscarinic Agonists; Nicotine; Oxotremorine; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Receptors, Nicotinic; Seizures

1997
Pharmacological characterization of nicotine's interaction with cocaine and cocaine analogs.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 289, Issue:3

    Topics: Animals; Body Temperature; Bupropion; Cocaine; Discrimination, Psychological; Female; Male; Membrane Potentials; Mice; Mice, Inbred ICR; Molecular Structure; Motor Activity; Nicotine; Oocytes; Pain; Piperazines; Psychomotor Performance; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Recombinant Proteins; Seizures; Structure-Activity Relationship; Tropanes; Xenopus laevis

1999
Chronic nicotine pretreatment protects the blood-brain barrier against nicotine-induced seizures in the rat.
    Pharmacological research, 1999, Volume: 40, Issue:3

    Topics: Animals; Blood-Brain Barrier; Brain; Capillary Permeability; Dose-Response Relationship, Drug; Male; Nicotine; Premedication; Rats; Rats, Wistar; Seizures

1999
Pharmacological characterization of nicotine-induced seizures in mice.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:3

    Topics: Animals; Anticonvulsants; Brain Chemistry; Calcium Signaling; Dihydropyridines; Glutamic Acid; Injections, Intraventricular; Injections, Subcutaneous; Male; Mice; Mice, Inbred ICR; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nitric Oxide; Receptors, N-Methyl-D-Aspartate; Receptors, Nicotinic; Seizures

1999
Potential role of the alpha4 and alpha6 nicotinic receptor subunits in regulating nicotine-induced seizures.
    The Journal of pharmacology and experimental therapeutics, 2000, Volume: 293, Issue:1

    Topics: Animals; Behavior, Animal; Blotting, Southern; DNA; Dose-Response Relationship, Drug; Gene Transfer Techniques; In Situ Hybridization; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; Seizures; Species Specificity

2000
Analgesic and toxic effects of ABT-594 resemble epibatidine and nicotine in rats.
    Pain, 2000, Volume: 85, Issue:3

    Topics: Analgesics, Non-Narcotic; Animals; Azetidines; Behavior, Animal; Body Temperature; Bridged Bicyclo Compounds, Heterocyclic; Hot Temperature; Hypertension; Male; Mecamylamine; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Pain Measurement; Postural Balance; Pyridines; Rats; Rats, Sprague-Dawley; Reaction Time; Seizures; Substance-Related Disorders

2000
Genetic and pharmacological strategies identify a behavioral function of neuronal nicotinic receptors.
    Behavioural brain research, 2000, Volume: 113, Issue:1-2

    Topics: Alkaloids; alpha7 Nicotinic Acetylcholine Receptor; Animals; Azocines; Behavior, Animal; Crosses, Genetic; Dose-Response Relationship, Drug; Female; Hippocampus; Humans; Hybridization, Genetic; Injections, Intraperitoneal; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Polymorphism, Restriction Fragment Length; Quinolizines; Receptors, Nicotinic; Seizures

2000
Influence of gender and sex hormones on nicotine acute pharmacological effects in mice.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 296, Issue:1

    Topics: Animals; Body Temperature; Electrophysiology; Female; Gonadal Steroid Hormones; In Vitro Techniques; Injections, Spinal; Male; Maze Learning; Mice; Mice, Inbred ICR; Motor Activity; Neurons; Nicotine; Nicotinic Agonists; Oocytes; Pain Measurement; Reaction Time; Receptors, Nicotinic; Seizures; Sex Factors; Xenopus laevis

2001
Nicotine produces selective degeneration in the medial habenula and fasciculus retroflexus.
    Brain research, 2001, Jul-06, Volume: 906, Issue:1-2

    Topics: Animals; Axons; Body Weight; Cotinine; Dose-Response Relationship, Drug; Efferent Pathways; Female; Habenula; Hyperkinesis; Nerve Degeneration; Neurotoxins; Nicotine; Nicotinic Agonists; Rats; Rats, Sprague-Dawley; Seizures; Silver Staining; Wallerian Degeneration

2001
Inhibition of nicotine-induced seizures in rats by combining vaccination against nicotine with chronic nicotine infusion.
    Experimental and clinical psychopharmacology, 2001, Volume: 9, Issue:2

    Topics: Animals; Brain; Carrier Proteins; Enzyme-Linked Immunosorbent Assay; Haptens; Immunoglobulin E; Infusions, Intravenous; Male; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Seizures; Vaccination

2001
Nicotine nasal inhalation, atrial fibrillation and seizures.
    Cardiology, 2001, Volume: 96, Issue:1

    Topics: Administration, Inhalation; Atrial Fibrillation; Ganglionic Stimulants; Humans; Male; Middle Aged; Nicotine; Seizures; Substance-Related Disorders

2001
Nicotine induced seizures blocked by mecamylamine and its stereoisomers.
    Life sciences, 2001, Oct-19, Volume: 69, Issue:22

    Topics: Animals; Disease Models, Animal; Male; Mecamylamine; Molecular Conformation; Nicotine; Nicotinic Antagonists; Rats; Rats, Sprague-Dawley; Seizures

2001
Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.
    Brain research. Molecular brain research, 2002, Jan-31, Volume: 98, Issue:1-2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Bridged Bicyclo Compounds, Heterocyclic; Bungarotoxins; Dose-Response Relationship, Drug; Female; Hippocampus; Injections, Intraperitoneal; Ligands; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicotine; Protein Subunits; Pyridines; Receptors, Nicotinic; RNA, Messenger; Seizures

2002
Increased sensitivity to nicotine-induced seizures in mice expressing the L250T alpha 7 nicotinic acetylcholine receptor mutation.
    Molecular pharmacology, 2002, Volume: 61, Issue:3

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Substitution; Animals; Dihydro-beta-Erythroidine; Disease Models, Animal; Electrophysiology; Female; Ganglionic Stimulants; Heterozygote; Hippocampus; Lysine; Male; Mice; Mice, Inbred C57BL; Neuroanatomy; Nicotine; Phenotype; Receptors, Nicotinic; Seizures; Threonine

2002
Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor.
    Neuroreport, 2002, Feb-11, Volume: 13, Issue:2

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Behavior, Animal; Electroencephalography; Ganglionic Stimulants; Genetic Predisposition to Disease; Heterozygote; Mice; Mice, Inbred C57BL; Mortality; Mutation; Nicotine; Receptors, Nicotinic; Reference Values; Seizures

2002
The selectively bred high alcohol sensitivity (HAS) and low alcohol sensitivity (LAS) rats differ in sensitivity to nicotine.
    Alcoholism, clinical and experimental research, 2002, Volume: 26, Issue:6

    Topics: Alcohol Drinking; Animals; Body Temperature; Brain; Female; Male; Motor Activity; Nicotine; Rats; Seizures

2002
The antinicotinic effects of drugs with clinically useful sedative-antianxiety properties.
    Pharmacology, 1975, Volume: 13, Issue:5

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Hypnotics and Sedatives; Male; Mice; Nicotine; Seizures

1975
Novel anxiolytic agents derived from alpha-amino-alpha-phenyl-o-tolyl-4H-triazoles and -imidazoles.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:6

    Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Brain; Crystallography; Hypnotics and Sedatives; Imidazoles; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Mice; Models, Molecular; Molecular Conformation; Muscle Relaxation; Nicotine; Pentylenetetrazole; Rats; Seizures; Semicarbazides; Triazoles

1978
Maturational changes related to dopamine in the effects of d-amphetamine, cocaine, nicotine, and strychnine on seizure susceptibility.
    Psychopharmacology, 1979, Volume: 64, Issue:3

    Topics: Aging; Animals; Cocaine; Dextroamphetamine; Dopamine; Mice; Myoclonus; Nicotine; Seizures; Strychnine

1979
The pharmacology of Avena sativa.
    The Journal of pharmacy and pharmacology, 1975, Volume: 27, Issue:2

    Topics: Animals; Barbiturates; Blood Pressure; Humans; Mice; Morphine; Morphine Dependence; Nicotine; Plant Extracts; Plants; Plants, Medicinal; Rats; Reaction Time; Seizures; Sleep; Time Factors

1975
Relations between nicotine-induced convulsive behavior and blood and brain levels of nicotine as a function of sex and age in two inbred strains of mice.
    Pharmacology, biochemistry, and behavior, 1979, Volume: 10, Issue:3

    Topics: Aging; Animals; Brain; Female; Genotype; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Nicotine; Seizures; Sex Factors; Species Specificity

1979
Electrophysiological, behavioral, and chemical evidence for a noncholinergic, stereospecific site for nicotine in rat brain.
    Journal of neuroscience research, 1978, Volume: 3, Issue:5-6

    Topics: Action Potentials; Animals; Behavior, Animal; Brain Mapping; Hippocampus; Male; Nicotine; Rats; Receptors, Cholinergic; Receptors, Nicotinic; Seizures; Stereoisomerism

1978
Butyrophenones as hypotensive agents. Derivatives of 4-aryl-4-(hydroxymethyl)cyclohexylamine.
    Journal of medicinal chemistry, 1975, Volume: 18, Issue:6

    Topics: Animals; Behavior, Animal; Blood Pressure; Butyrophenones; Cyclohexylamines; Depression, Chemical; Male; Methanol; Mice; Nicotine; Rats; Seizures

1975
Cow's urine poisoning in Nigeria. Experimental observations in mice.
    Tropical and geographical medicine, 1975, Volume: 27, Issue:2

    Topics: Animals; Cattle; Child; Dogs; Dose-Response Relationship, Drug; Female; Folklore; Humans; Injections, Intraperitoneal; Male; Medicine, Traditional; Mice; Nicotine; Nigeria; Pharmaceutical Vehicles; Plant Extracts; Rabbits; Rats; Seizures; Urine

1975
Central nervous system depressants. 13. s-Triazolo-1,5-benzodiazepin-5-ones.
    Journal of medicinal chemistry, 1976, Volume: 19, Issue:1

    Topics: Animals; Benzodiazepinones; Central Nervous System; Depression, Chemical; Male; Mice; Nicotine; Pentylenetetrazole; Reflex; Seizures; Strychnine; Triazoles

1976
Anticonvulsant activity of delta9-tetrahydrocannabinol compared with three other drugs.
    European journal of pharmacology, 1976, Volume: 35, Issue:1

    Topics: Animals; Anticonvulsants; Cannabis; Chlordiazepoxide; Dronabinol; Electroshock; Male; Mice; Nicotine; Pentylenetetrazole; Pharmaceutical Vehicles; Phenobarbital; Phenytoin; Seizures; Strychnine; Time Factors

1976
Effects of acute administration of nicotine on convulsive movements and blood levels of corticosterone in old rats.
    Japanese journal of pharmacology, 1992, Volume: 60, Issue:4

    Topics: Aging; Animals; Corticosterone; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Injections, Intraperitoneal; Male; Movement; Nicotine; Rats; Rats, Wistar; Seizures; Spectrophotometry, Ultraviolet; Tremor

1992
Tolerance to the convulsions induced by daily nicotine treatment in rats.
    Japanese journal of pharmacology, 1992, Volume: 59, Issue:4

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Injections, Intraperitoneal; Male; Nicotine; Rats; Rats, Wistar; Seizures; Time Factors; Tremor

1992
Characterization of cholinergic regulation of seizures by the midline thalamus.
    Neuropharmacology, 1992, Volume: 31, Issue:4

    Topics: Animals; Female; Neostigmine; Nicotine; Parasympathomimetics; Pentylenetetrazole; Pilocarpine; Rats; Rats, Inbred Strains; Reference Values; Scopolamine; Seizures; Thalamus; Tubocurarine

1992
4-Bromoacetamidoprocaine: an affinity ligand for brain muscarinic and nicotinic cholinergic receptors.
    Neurochemical research, 1992, Volume: 17, Issue:3

    Topics: Animals; Behavior, Animal; Brain; Carbachol; Chloromercuribenzoates; Hyperkinesis; Ligands; Mercaptoethanol; Molecular Structure; Naloxone; Nicotine; p-Chloromercuribenzoic Acid; Procaine; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Receptors, Nicotinic; Seizures

1992
5 alpha-Pregnan-3 alpha-ol-20-one blocks nicotine-induced seizures and enhances paired-pulse inhibition.
    European journal of pharmacology, 1990, Aug-28, Volume: 185, Issue:2-3

    Topics: Animals; Anticonvulsants; Electric Stimulation; Electrophysiology; Hippocampus; Male; Mice; Mice, Inbred C3H; Nicotine; Pregnanolone; Seizures

1990
Apnea and seizures caused by nicotine ingestion.
    Pediatric emergency care, 1990, Volume: 6, Issue:2

    Topics: Apnea; Female; Humans; Infant; Male; Nicotine; Seizures

1990
Strain comparison of nicotine-induced seizure sensitivity and nicotinic receptors.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:2

    Topics: Animals; Brain Chemistry; Bungarotoxins; Dose-Response Relationship, Drug; Infusions, Intravenous; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; Nicotine; Reaction Time; Receptors, Nicotinic; Seizures; Species Specificity

1989
Ethanol withdrawal tremor potentiates the tremorogenic action of nicotine.
    Medical biology, 1985, Volume: 63, Issue:3

    Topics: Animals; Ethanol; Hexamethonium; Hexamethonium Compounds; Male; Nicotine; Propranolol; Rats; Rats, Inbred Strains; Seizures; Substance Withdrawal Syndrome; Tremor

1985
Nicotine-induced convulsions in cats and central nicotinic receptors.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:6

    Topics: 5,6-Dihydroxytryptamine; Animals; Brain; Cats; Dopamine Antagonists; Female; Ganglionic Blockers; Hemicholinium 3; Hydroxydopamines; Injections, Intraventricular; Male; Nicotine; Oxidopamine; Parasympatholytics; Receptors, Nicotinic; Reserpine; Seizures; Serotonin Antagonists; Sympatholytics

1986
The effect of chronic nicotine treatment on nicotine-induced seizures.
    Psychopharmacology, 1988, Volume: 95, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Brain Chemistry; Drug Tolerance; Female; Mice; Mice, Inbred DBA; Nicotine; Receptors, Cholinergic; Receptors, Nicotinic; Seizures

1988
Genetic influences on acute responses to nicotine and nicotine tolerance in the mouse.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1

    Topics: Animals; Body Temperature; Brain; Bungarotoxins; Drug Tolerance; Female; Heart Rate; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Receptors, Nicotinic; Reflex, Startle; Respiration; Seizures

1988
Effect of nicotine pretreatment on nicotine-induced seizures.
    Pharmacology, biochemistry, and behavior, 1988, Volume: 29, Issue:2

    Topics: Animals; Brain; Drug Resistance; Female; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures; Species Specificity

1988
Nonmuscarinic neurotoxicity of oxotremorine.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 241, Issue:1

    Topics: Animals; Arecoline; Atropine; Atropine Derivatives; Benactyzine; Benztropine; Crying; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Male; Mecamylamine; Nervous System; Nicotine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Salivation; Scopolamine; Seizures; Time Factors

1987
Genetic analysis of nicotine-induced seizures and hippocampal nicotinic receptors in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Animals; Brain; Bungarotoxins; Hippocampus; Mathematics; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures

1986
Effect of d-nicotine on the l-nicotine-induced increase in gastric acid secretion in rats.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:2

    Topics: Animals; Gastric Acid; Injections, Intraventricular; Male; Mice; Mice, Inbred Strains; Nicotine; Rats; Rats, Inbred Strains; Seizures; Stereoisomerism

1985
Relationship between nicotine-induced seizures and hippocampal nicotinic receptors.
    Life sciences, 1985, Jul-08, Volume: 37, Issue:1

    Topics: Animals; Bungarotoxins; Hippocampus; In Vitro Techniques; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Nicotine; Receptors, Nicotinic; Seizures

1985
[Nicotine and pentetrazol-induced EEG changes in normal and hypothyroid rabbits].
    Naunyn-Schmiedebergs Archiv fur experimentelle Pathologie und Pharmakologie, 1967, Volume: 258, Issue:4

    Topics: Animals; Cerebral Cortex; Electroencephalography; Hippocampus; Hypothyroidism; Iodine Isotopes; Methylthiouracil; Nicotine; Pentylenetetrazole; Perchlorates; Rabbits; Seizures; Thyroid Gland

1967
Pharmacological study of the central nicotine-sensitive cholino-receptors.
    Activitas nervosa superior, 1966, Volume: 8, Issue:1

    Topics: Animals; Ganglionic Blockers; Mice; Muscles; Nicotine; Seizures; Sensory Receptor Cells

1966
Tremorigenic and convulsant actions of intracerebrally administered vegetative poisons in the mouse.
    Acta physiologica Academiae Scientiarum Hungaricae, 1967, Volume: 31, Issue:3

    Topics: Acetylcholine; Animals; Autonomic Nervous System; Carbachol; Central Nervous System Stimulants; Histamine; Hormones; Indoles; Mice; Nicotine; Parasympathomimetics; Physostigmine; Pilocarpine; Piperazines; Pyridines; Pyrrolidines; Quaternary Ammonium Compounds; Seizures; Serotonin; Strychnine; Tremor; Tremorine; Tubocurarine

1967
Pharmacological studies on antagonists against nicotine-induced convulsions and death.
    Japanese journal of pharmacology, 1966, Volume: 16, Issue:4

    Topics: Animals; Anticonvulsants; Chlorpromazine; Drug Antagonism; Female; Ganglionic Blockers; Hexamethonium Compounds; Histamine H1 Antagonists; Male; Meprobamate; Mice; Nicotine; Parasympatholytics; Perphenazine; Phenobarbital; Phentolamine; Reserpine; Seizures; Sympatholytics; Thiazoles; Tolazoline; Tranquilizing Agents; Urea

1966
Synthesis and pharmacological action of some N-alkyl morpholines and their salts.
    The Journal of pharmacy and pharmacology, 1968, Volume: 20

    Topics: Acetylcholine; Animals; Female; Magnetic Resonance Spectroscopy; Mice; Morpholines; Nicotine; Pain; Pentylenetetrazole; Seizures; Spectrophotometry; Ultraviolet Rays

1968
Effects of ganglion blocking agents on nicotine extensor convulsions and lethality in mice.
    British journal of pharmacology, 1969, Volume: 37, Issue:1

    Topics: Animals; Atropine; Cerebral Ventricles; Chlorisondamine; Chlorpromazine; Decamethonium Compounds; Ganglionic Blockers; Hexamethonium Compounds; Male; Mecamylamine; Mice; Morphine; Nicotine; Phenobarbital; Seizures

1969
Antagonism of intracerebrally induced nicotinic convulsions in mice: a method for measuring the central antinicotinic activity of CNS acting agents.
    Psychopharmacologia, 1971, Volume: 19, Issue:1

    Topics: Adrenergic alpha-Antagonists; Animals; Anticonvulsants; Antidepressive Agents; Atropine; Biological Assay; Brain; Chemoreceptor Cells; Chlorisondamine; Chlorpromazine; Female; Histamine H1 Antagonists; Injections, Spinal; Male; Mice; Nicotine; Parasympatholytics; Seizures; Sympatholytics

1971
Experimental evidence for imipramine like activity of fenfluramine.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 188, Issue:2

    Topics: Animals; Avoidance Learning; Blepharoptosis; Blood Pressure; Body Temperature; Cats; Columbidae; Drug Antagonism; Drug Synergism; Electroshock; Female; Fenfluramine; Histamine H1 Antagonists; Hypothermia; Imipramine; Male; Mice; Nicotine; Nictitating Membrane; Rabbits; Rats; Reserpine; Respiration; Seizures; Tetrabenazine; Tremor; Tremorine; Vomiting; Yohimbine

1970
Partly reduced biphenyls as central nervous system agents. 2. cis- and trans-4-Arylcyclohexylamines.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:12

    Topics: Animals; Behavior, Animal; Biphenyl Compounds; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Seizures; Structure-Activity Relationship

1972
Partly reduced biphenyls as central nervous system agents. 1. 4-Arylcyclohex-3-enylamines.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:12

    Topics: Animals; Behavior, Animal; Biphenyl Compounds; Carbon Isotopes; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Motor Activity; Myocardium; Nicotine; Norepinephrine; Seizures; Serotonin; Spleen; Structure-Activity Relationship; Tritium

1972
Central nervous system agents. 4. Analogs of 3-amino-2-phenylpropiophenone.
    Journal of medicinal chemistry, 1972, Volume: 15, Issue:12

    Topics: Amines; Animals; Appetite; Behavior, Animal; Central Nervous System; Electroshock; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Propiophenones; Seizures; Structure-Activity Relationship

1972
Brain development in offspring of rats treated with nicotine during pregnancy.
    Experientia, 1973, Mar-15, Volume: 29, Issue:3

    Topics: Animals; Animals, Newborn; Brain; Electrophysiology; Electroshock; Female; Maternal-Fetal Exchange; Nicotine; Organ Size; Pregnancy; Rats; Seizures

1973
A study of structure-activity relationships of a series of diphenylaminopropanols by factor analysis.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:6

    Topics: Amino Alcohols; Animals; Behavior, Animal; Chemical Phenomena; Chemistry, Physical; Electroshock; Factor Analysis, Statistical; Isomerases; Mice; Nicotine; Pupil; Seizures; Structure-Activity Relationship; Thiosemicarbazones

1973
Central cholinomimetic actions of 3, 3-dimethyl-1-butanol carbamate.
    Journal of pharmaceutical sciences, 1973, Volume: 62, Issue:9

    Topics: Acetylcholine; Animals; Atropine; Brain; Carbamates; Carbon Isotopes; Dose-Response Relationship, Drug; Drug Interactions; Hydrolysis; In Vitro Techniques; Kinetics; Lethal Dose 50; Mice; Mice, Inbred ICR; Nerve Endings; Nicotine; Parasympathomimetics; Physostigmine; Rats; Rats, Inbred Strains; Seizures; Time Factors

1973
Partly reduced biphenyls as cetral nervous system agents. 3. Cis- and trans-4-aryl-4-methoxycyclohexylamines.
    Journal of medicinal chemistry, 1973, Volume: 16, Issue:11

    Topics: Animals; Behavior, Animal; Biphenyl Compounds; Carbon Radioisotopes; Central Nervous System; Cyclohexylamines; Lethal Dose 50; Male; Methyl Ethers; Mice; Mice, Inbred Strains; Motor Activity; Myocardium; Nicotine; Norepinephrine; Seizures; Serotonin; Spleen; Stereoisomerism; Tritium

1973
Neuropharmacological study of prostaglandin (PG)F2a.
    Journal of the Indian Medical Association, 1973, Nov-16, Volume: 61, Issue:10

    Topics: Analgesia; Animals; Body Temperature; Cerebral Ventricles; Escape Reaction; Injections; Motor Activity; Nicotine; Pentobarbital; Perphenazine; Prostaglandins; Seizures; Sleep; Tremorine

1973
Differentiation between effects of nicotine and DMPP by amantadine.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 203, Issue:2

    Topics: Acetylcholine; Amantadine; Animals; Blood Pressure; Cats; Drug Antagonism; Drug Interactions; Drug Synergism; Female; Ganglia, Autonomic; Male; Nicotine; Nictitating Membrane; Oxotremorine; Piperazines; Seizures

1973
Antin ociceptive activity of nicotine.
    Acta physiologica Academiae Scientiarum Hungaricae, 1973, Volume: 44, Issue:1

    Topics: Acetates; Analgesia; Animals; Dimethylphenylpiperazinium Iodide; Drug Tolerance; Injections, Intraperitoneal; Mecamylamine; Methods; Mice; Nicotine; Oxotremorine; Pain; Physostigmine; Rats; Reaction Time; Seizures; Tremorine

1973
[The effects of sulpiride on the central nervous system].
    Pathologie-biologie, 1969, Volume: 17, Issue:1

    Topics: Amphetamine; Analgesia; Animals; Atropine; Chlorpromazine; Male; Mescaline; Mice; Morphine; Nicotine; Pyrrolidines; Rabbits; Rats; Seizures; Serotonin; Serotonin Antagonists; Shock; Statistics as Topic; Sulfonic Acids; Tranquilizing Agents; Tremor; Tremorine; Tryptamines

1969
[Prevention of certain acute and chronic effects of nicotine by N-acetylhydroxyproline].
    Pathologie-biologie, 1971, Volume: 19, Issue:9

    Topics: Animals; Cerebral Cortex; Electroencephalography; Female; Humans; Hydroxyproline; Hypertension; Male; Nicotine; Rabbits; Seizures; Smoking

1971
The effect of elantrine, a new anti-Parkinsonism agent, on drug-induced tremor in mice.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 197, Issue:1

    Topics: Alkaloids; Animals; Antiparkinson Agents; Atropine; Benztropine; Body Temperature; Central Nervous System; Dibenzazepines; Drug Antagonism; Indoles; Male; Methylamines; Mice; Nicotine; Oxotremorine; Parasympatholytics; Procyclidine; Pupil; Pyridines; Seizures; Tremor; Trihexyphenidyl

1972
A new 2,6-difluorobenzodiazepinone.
    Journal of pharmaceutical sciences, 1972, Volume: 61, Issue:2

    Topics: Animals; Behavior, Animal; Benzazepines; Drug Synergism; Electroshock; Ethanol; Fluorine; Ketones; Male; Mice; Mice, Inbred Strains; Motor Activity; Nicotine; Pentylenetetrazole; Seizures; Structure-Activity Relationship; Strychnine; Thiosemicarbazones

1972
Central nervous system depressants. 9. Benzodiazepine sulfonamides.
    Journal of medicinal chemistry, 1971, Volume: 14, Issue:17

    Topics: Animals; Benzazepines; Benzodiazepinones; Central Nervous System; Depression, Chemical; Drug Synergism; Electroshock; Ethanol; Lethal Dose 50; Male; Motor Activity; Nicotine; Seizures; Sulfonamides

1971
The contents of DOPA and catecholamines in several rat tissues and nicotine-induced convulsions.
    Japanese journal of pharmacology, 1966, Volume: 16, Issue:3

    Topics: Adrenal Glands; Animals; Brain Chemistry; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Epinephrine; Liver; Male; Mice; Monoamine Oxidase; Myocardium; Nicotine; Norepinephrine; Rats; Seizures

1966
Effect of reserpine on brain levels of 14C-nicotine in relation to nicotine-induced convulsions.
    Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 166, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbon Isotopes; Chlorpromazine; Dihydroxyphenylalanine; Injections, Intraperitoneal; Liver; Male; Mice; Nicotine; Phenobarbital; Reserpine; Seizures

1967
A simple method to measure central antinocotinic activity.
    Japanese journal of pharmacology, 1969, Volume: 19, Issue:1

    Topics: Animals; Atropine; Brain; Female; Infusions, Parenteral; Injections; Male; Methods; Mice; Nicotine; Phenobarbital; Phenytoin; Seizures

1969
Pyrrolo[3,2,1-jk][1,4]benzodiazepines and pyrrolo[1,2,3-ef][1,5]benzodiazepines which have central nervous system activity.
    Journal of medicinal chemistry, 1970, Volume: 13, Issue:5

    Topics: Animals; Behavior, Animal; Benzazepines; Central Nervous System; Chemical Phenomena; Chemistry; Diazepam; Male; Mice; Muscle Contraction; Nicotine; Pyrroles; Reflex; Seizures

1970
[Effect of nicotine on the development of audiogenic convulsions in animals of various ages].
    Biulleten' eksperimental'noi biologii i meditsiny, 1970, Volume: 69, Issue:3

    Topics: Age Factors; Animals; Guinea Pigs; Injections, Intraperitoneal; Mice; Nicotine; Rats; Seizures; Sound; Species Specificity

1970
[2-ethylamino-6-chloro-4-methyl-4-phenyl-4H-3,1-benzoxazine, a new psychotropic compound].
    Arzneimittel-Forschung, 1970, Volume: 20, Issue:7

    Topics: Aggression; Alcohols; Animals; Behavior, Animal; Central Nervous System; Chemistry, Pharmaceutical; Cricetinae; Depression, Chemical; Drug Synergism; Fear; Hexobarbital; Humans; Magnetic Resonance Spectroscopy; Mice; Motor Activity; Nicotine; Oxazines; Psychopharmacology; Rats; Seizures; Spectrum Analysis; Stimulation, Chemical; Tranquilizing Agents

1970
Studies on the anticonvulsant properties of some benzodiazepines. (Chlordiazepoxide, diazepam, oxazepam).
    Arzneimittel-Forschung, 1967, Volume: 17, Issue:12

    Topics: Action Potentials; Animals; Anticonvulsants; Chlordiazepoxide; Diazepam; Electroencephalography; Female; Male; Morphine; Nicotine; Oxazepam; Phenobarbital; Phenytoin; Rabbits; Seizures; Strychnine

1967
Tetraethylammonium chloride as an antidote for certain insecticides in mice.
    Science (New York, N.Y.), 1968, Mar-22, Volume: 159, Issue:3821

    Topics: Animals; Antidotes; Atropine; Carbamates; Insecticides; Mice; Nicotine; Parathion; Seizures; Tetraethylammonium Compounds

1968
The central nervous effects of bis-(4-aminophenyl)-alkyl derivatives.
    Acta physiologica Academiae Scientiarum Hungaricae, 1968, Volume: 34, Issue:4

    Topics: Animals; Barbiturates; Blood-Brain Barrier; Brain; Chickens; Drug Synergism; Electroencephalography; Guinea Pigs; Kidney; Liver; Mice; Nicotine; Norepinephrine; Pentylenetetrazole; Propylamines; Rats; Seizures; Solubility

1968
[vidence for a muscarinic inhibitory mechanism in the cerebral cortex].
    Experimental neurology, 1969, Volume: 23, Issue:3

    Topics: Acetylcholine; Animals; Atropine; Cats; Cerebral Cortex; Drug Antagonism; Electric Stimulation; Electrophysiology; Female; Male; Mecamylamine; Nicotine; Nicotinic Acids; Parasympathomimetics; Physostigmine; Pilocarpine; Pyrrolidines; Scopolamine; Seizures; Tremorine

1969
Some pharmacological properties of 4H-3-methylcarboxamide 1,3-benzoxazine-2-one (FI 6654).
    European journal of pharmacology, 1969, Volume: 6, Issue:3

    Topics: Acetylcholine; Animals; Antidepressive Agents; Arousal; Atropine; Barium; Duodenum; Electroencephalography; Guinea Pigs; Histamine; Ileum; Imipramine; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Nicotine; Oxazines; Papaverine; Physostigmine; Rabbits; Rats; Seizures; Serotonin

1969
Action of topically applied atropine, eserine, acetylcholine and nicotine on cortical epilepsy in the rabbit.
    Archives internationales de pharmacodynamie et de therapie, 1969, Volume: 177, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Electric Stimulation; Nicotine; Physostigmine; Rabbits; Seizures

1969
Pharmacology of diphenylalkyl derivatives. II. Pharmacology of beta,beta-bis-(4-aminophenyl)-propionitrile.
    Acta physiologica Academiae Scientiarum Hungaricae, 1966, Volume: 30, Issue:2

    Topics: Aminopropionitrile; Animals; Anticonvulsants; Blood Circulation; Blood Pressure; Cats; Electroshock; Mice; Nicotine; Nitriles; Rats; Reflex; Seizures; Strychnine

1966