nicorandil has been researched along with Coronary Heart Disease in 82 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (29.27) | 18.7374 |
| 1990's | 32 (39.02) | 18.2507 |
| 2000's | 16 (19.51) | 29.6817 |
| 2010's | 5 (6.10) | 24.3611 |
| 2020's | 5 (6.10) | 2.80 |
| Authors | Studies |
|---|---|
| Du, X; Li, L; Ma, Z; Zhong, X | 1 |
| Li, N; Liu, J; Qiu, L; Shen, L; Shu, H; Zhou, N | 1 |
| Li, J; Xu, X; Zong, Y | 1 |
| Fu, N; Yang, S; Zhang, P; Zhang, X | 1 |
| Fu, N; Li, Y; Zeng, Z; Zhang, H; Zhang, P | 1 |
| Pang, Z; Yao, Z; Zhao, W | 1 |
| Kawasaki, M; Kinomura, Y; Minatoguchi, S; Nawa, T; Nishigaki, K; Tanaka, T; Yamada, Y | 1 |
| Akasaka, T; Emori, H; Hozumi, T; Ino, Y; Kameyama, T; Katayama, Y; Kubo, T; Kuroi, A; Matsuo, Y; Nishiguchi, T; Orii, M; Shimamoto, Y; Takemoto, K; Tanabe, K; Tanaka, A; Taruya, A; Terada, M; Yamaguchi, T; Yamano, T | 1 |
| Hashimoto, T; Iwamoto, N; Kobayashi, H; Murakawa, M; Nishida, M; Nishimura, M; Okamoto, Y; Ono, T; Sakoda, C; Sato, N; Takahashi, H; Tokoro, T; Yamazaki, S | 1 |
| Ginzburg, ML; Malysheva, AM; Martsevich, SIu | 1 |
| Ostrovskiĭ, IuP; Sidorenko, GI | 1 |
| Greenwood, JP; Jennings, P; Malik, I; Stevenson, RN | 1 |
| Miki, T; Miura, T | 1 |
| Ahn, YK; Cho, JG; Jeong, MH; Kang, JC; Kim, W; Park, JC | 1 |
| Furukawa, H; Iwasaki, K; Samukawa, M | 1 |
| Egred, M | 1 |
| Inoue, S; Sadamatsu, K; Tashiro, H | 1 |
| Gottwik, M; Kramer, W; Schlepper, M; Thormann, J | 1 |
| Abiko, Y; Nishimura, T; Sakai, K | 1 |
| Gross, GJ; Hardman, HF; Lamping, KA; Warltier, DC | 1 |
| Darmon, JY; Witchitz, S | 1 |
| Adachi, H; Hiroe, M; Kano, H; Koike, A; Korenaga, M; Marumo, F; Miyahara, Y; Shimizu, N; Sugimoto, K; Yajima, T | 1 |
| Hongo, M; Nakatsuka, T; Sekiguchi, M; Takenaka, H; Uchikawa, S; Watanabe, N | 1 |
| Haeusler, G; Lues, I | 1 |
| Ambrosio, G; Chiariello, M; Duilio, C | 1 |
| Arnold, JM; Hearron, AE; Jungbluth, GL; Kowey, PR; Luderer, JR; Wolf, DL | 1 |
| Suryapranata, H | 1 |
| Richardson, PJ; Why, HJ | 1 |
| Blin, P; Guermonprez, JL; Peterlongo, F | 1 |
| Hughes, LO; Lahiri, A; Raftery, EB; Rose, EL | 1 |
| Kato, K | 1 |
| Fujita, M; Igawa, A; Inouc, H; Miwa, K; Yamanishi, K | 1 |
| Frishman, WH; Goldschmidt, M; Landzberg, BR | 1 |
| Murayama, S; Nakano, T; Yamakado, T | 1 |
| Ito, M; Kinoshita, M; Liu, Q; Nakae, I; Takaoka, A; Yamamoto, K | 1 |
| Kanki, H; Nishikawa, Y; Ogawa, S | 1 |
| Haager, PK; Hanrath, P; Klues, HG; Schmidt, M; vom Dahl, J | 1 |
| Courville, P; Delcampe, P; Metayer, J; Peron, JM; Roussel, S | 1 |
| Johnston, PW; Webb, SW | 1 |
| Bickel, C; Meyer, J; Rörig, J; Rupprecht, HJ; Tyrtania, A | 1 |
| Iwamoto, Y; Nakagami, T; Wasada, T; Watanabe, C | 1 |
| Boes, U; Wallner, S; Wascher, TC | 1 |
| Abe, Y; Endo, M; Hirano, Y; Kasashima, F; Kawashima, S; Matsumoto, Y; Sasaki, H; Ueyama, T | 1 |
| Das, B; Karanth, KS; Sarkar, C | 1 |
| SoRelle, R | 1 |
| Matsui, K; Ohashi, N; Sasabe, M; Yamamoto, S | 1 |
| Chou, TF; Lee, TM; Lee, YT; Su, SF; Tsai, CH | 1 |
| Clark, AL; Cleland, JG; Coletta, AP; Louis, AA; Manousos, IR | 1 |
| MacLeod, D; Suryapranata, H | 1 |
| Erbel, R; Meyer, J; Treese, N | 1 |
| Diderholm, E; Frithz, G; Gudbrandsson, T; Hedbäck, B; Höglund, C; Moelstad, P; Perk, J; Sverrisson, JT; Ulvenstam, G | 1 |
| Döring, G | 1 |
| Kinugawa, T; Kitamura, H; Kotake, H; Mashiba, H; Matsumoto, T; Miyakoda, H; Noguchi, N; Ogino, K | 1 |
| Grover, GJ; Parham, CS; Sleph, PG | 1 |
| Fukamachi, K; Fukumura, F; Kinoshita, K; Kurisu, K; Mitani, A; Nakashima, A; Sakamoto, M; Tokunaga, K; Tsuruhara, Y | 1 |
| Fukushima, H; Harada, K; Jinno, Y; Nishikori, K; Ogawa, N; Ohta, H | 1 |
| Hata, N; Iwahara, S; Kishida, H; Koumi, S; Kusama, Y; Mori, N; Munakata, K; Sasaki, Y; Takayama, M; Yasutake, M | 1 |
| Amioka, H; Hashimoto, M; Kajiyama, G; Matsuura, H; Okamoto, M; Tsuchioka, Y; Yamagata, T | 1 |
| Chen, SL; Feng, XB; Li, LS; Zang, YM; Zhu, MZ | 1 |
| Kambara, H; Kawai, C; Nakamura, Y; Tamaki, S | 2 |
| Hakuta, T; Kobayashi, K | 1 |
| Aizawa, T; Kato, K; Ogasawara, K | 1 |
| Gross, GJ; Pieper, GM; Warltier, DC | 1 |
| Abiko, Y; Ichihara, K; Sakai, K | 1 |
| Abe, S; Hattori, S; Kojima, S; Miyamori, R; Miyazaki, T; Mori, H; Nakamura, Y; Sakurai, K; Takahashi, M | 1 |
| Endo, T; Fujita, S; Hayakawa, H; Kikuchi, K; Kiuchi, K; Nejima, J; Okumura, H | 1 |
| Haneda, T; Ichihara, K; Onodera, S | 1 |
| Farber, NE; Gross, G; Hardman, H; Pieper, G; Warltier, D | 1 |
| Coltart, DJ; Signy, M | 1 |
| Serruys, PW; Suryapranata, H | 1 |
| Hawgood, BJ; Kempsford, RD | 1 |
| Gross, GJ; Pieper, GM | 2 |
| Heere, TJ; Sassen, LM; Saxena, PR; Soei, LK; van Woerkens, LJ; Verdouw, PD | 1 |
| Geshi, E; Hiroshige, J; Katagiri, T; Konno, N; Mochizuki, M; Umetsu, K | 1 |
| Brooks, HL; Gross, GJ; Preuss, KC; Shimshak, TM; Warltier, DC | 1 |
| De Feyter, PJ; Hugenholtz, PG; Serruys, PW; Suryapranata, H; Verdouw, PD | 1 |
| Irié, H | 1 |
| Hellige, G; Hoeft, A; Hunneman, DH; Korb, H; Schraeder, R; Wolpers, HG | 1 |
13 review(s) available for nicorandil and Coronary Heart Disease
| Article | Year |
|---|---|
[Cardioprotective characteristics of the drug nicorandil in patients with coronary heart disease].
Topics: Administration, Oral; Biological Availability; Cardiotonic Agents; Clinical Trials as Topic; Coronary Disease; Humans; Nicorandil; Treatment Outcome | 2011 |
[The no-reflow phenomenon and its clinical significance].
Topics: Adenosine; Angioplasty, Balloon, Coronary; Atherectomy; Coronary Angiography; Coronary Artery Bypass; Coronary Circulation; Coronary Disease; Heart Failure; Hospital Mortality; Humans; Microvascular Angina; Myocardial Infarction; Nicorandil; Platelet Glycoprotein GPIIb-IIIa Complex; Risk Factors; Stents; Vasodilator Agents; Verapamil | 2002 |
ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Diazoxide; Glyburide; Humans; Ion Channel Gating; Myocardial Reperfusion Injury; Nicorandil; Pinacidil; Potassium Channel Blockers; Potassium Channels; Randomized Controlled Trials as Topic; Vasodilator Agents | 2003 |
Nicorandil-associated ulcerations.
Topics: Coronary Disease; Gastrointestinal Diseases; Humans; Nicorandil; Potassium Channels; Ulcer; Vasodilator Agents | 2007 |
Therapeutic potential of potassium channel activators in coronary heart disease.
Topics: Animals; Coronary Disease; Coronary Vessels; Heart; Humans; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1994 |
[Anti-angina activity of potassium-channel activators].
Topics: Angina Pectoris; Clinical Trials as Topic; Coronary Disease; Humans; Niacinamide; Nicorandil; Potassium Channels | 1993 |
Coronary haemodynamics and vasodilatory profile of a potassium channel opener in patients with coronary artery disease.
Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Hemodynamics; Humans; Myocardial Ischemia; Niacinamide; Nicorandil; Potassium Channels; Vasodilation; Vasodilator Agents | 1993 |
A potassium channel opener as monotherapy in chronic stable angina pectoris: comparison with placebo.
Topics: Angina Pectoris; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Exercise Test; Humans; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1993 |
Haemodynamic and clinical effects of an intravenous potassium channel opener--a review.
Topics: Administration, Sublingual; Angina, Unstable; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Niacinamide; Nicorandil; Nitroglycerin; Potassium Channels; Vasodilator Agents | 1993 |
Nicorandil: a potassium channel opening drug for treatment of ischemic heart disease.
Topics: Clinical Trials as Topic; Coronary Disease; Hemodynamics; Humans; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1996 |
Clinical trials update: The Heart Protection Study, IONA, CARISA, ENRICHD, ACUTE, ALIVE, MADIT II and REMATCH. Impact Of Nicorandil on Angina. Combination Assessment of Ranolazine In Stable Angina. ENhancing Recovery In Coronary Heart Disease patients. As
Topics: Acetanilides; Angina Pectoris; Arrhythmias, Cardiac; Cardiology; Clinical Trials as Topic; Comorbidity; Coronary Disease; Defibrillators, Implantable; Depressive Disorder; Electric Countershock; Female; Heart Failure; Humans; Male; Nicorandil; Piperazines; Ranolazine; Sensitivity and Specificity | 2002 |
Acute hemodynamic effects of nicorandil in coronary artery disease.
Topics: Animals; Coronary Disease; Dogs; Hemodynamics; Humans; Niacinamide; Nicorandil; Vasodilator Agents | 1992 |
Effects of nicorandil on coronary circulation and myocardial ischemia.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Niacinamide; Nicorandil; Vasodilator Agents | 1989 |
25 trial(s) available for nicorandil and Coronary Heart Disease
| Article | Year |
|---|---|
Nicorandil Decreases Renal Injury in Patients With Coronary Heart Disease Complicated With Type I Cardiorenal Syndrome.
Topics: Aged; Aged, 80 and over; Biomarkers; Cardio-Renal Syndrome; Cardiovascular Agents; China; Coronary Disease; Creatinine; Cystatin C; Female; Functional Status; Hepatitis A Virus Cellular Receptor 1; Humans; Interleukin-18; Kidney; Lipocalin-2; Male; Middle Aged; Natriuretic Peptide, Brain; Nicorandil; Prospective Studies; Recovery of Function; Time Factors; Treatment Outcome; Ventricular Function, Left | 2021 |
Effects of nicorandil on systemic inflammation and oxidative stress induced by percutaneous coronary intervention in patients with coronary heart disease.
Topics: Coronary Disease; Humans; Inflammation; Nicorandil; Oxidative Stress; Percutaneous Coronary Intervention | 2021 |
Efficacy of nicorandil on the prevention of contrast-induced nephropathy in patients with coronary heart disease undergoing percutaneous coronary intervention.
Topics: Acute Coronary Syndrome; Acute Kidney Injury; Aged; Angina, Stable; Blood Urea Nitrogen; Contrast Media; Coronary Disease; Creatinine; Cystatin C; Female; Humans; Male; Middle Aged; Nicorandil; Percutaneous Coronary Intervention; Vasodilator Agents | 2020 |
Standard vs. double dose of intravenous nicorandil in preventing contrast-induced nephropathy in patients with coronary heart disease undergoing elective coronary procedures.
Topics: Administration, Intravenous; Aged; China; Contrast Media; Coronary Disease; Creatinine; Female; Humans; Kidney Diseases; Male; Nicorandil; Prospective Studies; Single-Blind Method | 2021 |
Cardioprotective Effects of Nicorandil on Coronary Heart Disease Patients Undergoing Elective Percutaneous Coronary Intervention.
Topics: Blood Pressure; Cardiotonic Agents; Coronary Disease; Creatine Kinase, MB Form; Diastole; Elective Surgical Procedures; Female; Heart Rate; Humans; Male; Malondialdehyde; Middle Aged; Nicorandil; No-Reflow Phenomenon; Percutaneous Coronary Intervention; Peroxidase; Stroke Volume; Systole; Troponin I | 2017 |
Continuous intravenous infusion of nicorandil for 4 hours before and 24 hours after percutaneous coronary intervention protects against contrast-induced nephropathy in patients with poor renal function.
Topics: Acute Kidney Injury; Aged; Contrast Media; Coronary Angiography; Coronary Disease; Creatinine; Cystatin C; Female; Glomerular Filtration Rate; Humans; Infusions, Intravenous; Kidney Function Tests; Male; Middle Aged; Nicorandil; Percutaneous Coronary Intervention; Perioperative Care; Postoperative Complications; Protective Agents; Regression Analysis; Renal Insufficiency, Chronic; Treatment Outcome | 2015 |
Impact of nicorandil in angina: subgroup analyses.
Topics: Angina Pectoris; Confidence Intervals; Coronary Disease; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Nicorandil; Proportional Hazards Models; Risk Factors; Treatment Outcome; Vasodilator Agents | 2004 |
Comparison of the effects of nicorandil versus verapamil on the incidence of slow flow/no reflow during rotational atherectomy.
Topics: Aged; Anticoagulants; Atherectomy, Coronary; Biomarkers; Coronary Circulation; Coronary Disease; Creatine Kinase; Female; Heparin; Humans; Infusions, Intravenous; Male; Middle Aged; Nicorandil; Prospective Studies; Recurrence; Treatment Outcome; Troponin T; Vasodilator Agents; Verapamil | 2006 |
Nicorandil safety in the long-term treatment of coronary heart disease.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Blood Pressure; Chronic Disease; Coronary Disease; Drug Interactions; Female; Heart Rate; Humans; Long-Term Care; Male; Middle Aged; Niacinamide; Nicorandil; Prospective Studies | 1995 |
Effects of nicorandil on kinetics of oxygen uptake at the onset of exercise in patients with coronary artery disease.
Topics: Adult; Aged; Coronary Disease; Cross-Over Studies; Double-Blind Method; Exercise; Exercise Test; Female; Hemodynamics; Humans; Kinetics; Male; Middle Aged; Niacinamide; Nicorandil; Oxygen; Vasodilator Agents | 1995 |
Coronary microvascular response to intracoronary administration of nicorandil.
Topics: Adult; Aged; Angina Pectoris; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Coronary Vessels; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Male; Microcirculation; Middle Aged; Niacinamide; Nicorandil; Papaverine; Vascular Resistance; Vasodilator Agents | 1995 |
Dose-related haemodynamic effects and pharmacokinetics of oral nicorandil in patients evaluated for chest pain.
Topics: Analysis of Variance; Cardiac Catheterization; Chest Pain; Coronary Disease; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Time Factors; Vasodilator Agents | 1994 |
A double-blind comparison of the long-term efficacy of a potassium channel opener and a calcium antagonist in stable angina pectoris.
Topics: Aged; Angina Pectoris; Coronary Circulation; Coronary Disease; Diltiazem; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Electrocardiography; Exercise Test; Female; Humans; Male; Middle Aged; Myocardial Infarction; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1993 |
A double-blind comparison of a beta-blocker and a potassium channel opener in exercise induced angina.
Topics: Aged; Angina Pectoris; Atenolol; Blood Pressure; Coronary Circulation; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilator Agents | 1993 |
Effective and safe dose of intracoronary nicorandil in man.
Topics: Aged; Coronary Angiography; Coronary Disease; Coronary Vessels; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Injections, Intra-Arterial; Male; Middle Aged; Niacinamide; Nicorandil; Oxygen; Vasodilation; Vasodilator Agents | 1995 |
Effects of nicorandil, an antianginal potassium channel opener, on left ventricular systolic and diastolic function in patients with chronic coronary artery disease.
Topics: Adult; Aged; Chronic Disease; Coronary Disease; Diastole; Female; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Potassium Channels; Systole; Vasodilator Agents; Ventricular Function, Left; Ventricular Pressure | 1997 |
Differential effects of N-acetylcysteine on nitroglycerin- and nicorandil-induced vasodilation in human coronary circulation.
Topics: Acetylcysteine; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Free Radical Scavengers; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents | 1998 |
Effect of nitroglycerin and nicorandil on regional poststenotic quantitative coronary blood flow in coronary artery disease: a combined digital quantitative angiographic and intracoronary doppler study.
Topics: Coronary Angiography; Coronary Circulation; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Nicorandil; Nitroglycerin; Ultrasonography, Doppler; Vasodilator Agents | 1999 |
[Nicorandil: acute hemodynamic effects of 2 different oral doses of a potassium channel opener in patients with coronary heart disease].
Topics: Administration, Oral; Adult; Aged; Angina Pectoris; Calcium Channels; Coronary Circulation; Coronary Disease; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Male; Middle Aged; Monitoring, Physiologic; Nicorandil; Treatment Outcome | 1999 |
Adenosine triphosphate-sensitive potassium channels are involved in insulin-mediated glucose transport in humans.
Topics: Adenosine Triphosphate; Aged; ATP-Binding Cassette Transporters; Blood Glucose; C-Peptide; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Glycated Hemoglobin; Humans; Insulin; KATP Channels; Male; Middle Aged; Nicorandil; Potassium Channels; Potassium Channels, Inwardly Rectifying | 1999 |
Acute effects of nicorandil on glucose tolerance in subjects with borderline fasting blood glucose levels.
Topics: Administration, Oral; Blood Glucose; C-Peptide; Coronary Disease; Fasting; Female; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Male; Middle Aged; Nicorandil; Radioimmunoassay; Time Factors; Vasodilator Agents | 2001 |
Trial to show the impact of nicorandil in angina (IONA): design, methodology, and management.
Topics: Angina Pectoris; Chest Pain; Cohort Studies; Coronary Disease; Double-Blind Method; Female; Hospitalization; Humans; Male; Middle Aged; Myocardial Infarction; Nicorandil; Research Design; Risk Factors; Treatment Outcome; Vasodilator Agents | 2001 |
Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty.
Topics: Adult; Aged; Aging; Angioplasty, Balloon, Coronary; ATP-Binding Cassette Transporters; Chest Pain; Coronary Disease; Electrocardiography; Female; Glyburide; Hemodynamics; Humans; Ischemic Preconditioning, Myocardial; KATP Channels; Lactic Acid; Male; Middle Aged; Myocardium; Nicorandil; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying | 2002 |
Antianginal and anti-ischemic efficacy of nicorandil compared with nifedipine in patients with angina pectoris and coronary heart disease: a double-blind, randomized, multicenter study.
Topics: Adult; Aged; Angina Pectoris; Blood Pressure; Coronary Disease; Double-Blind Method; Electrocardiography; Exercise; Female; Heart Rate; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nifedipine; Potassium Channels; Tablets | 1992 |
Antianginal and anti-ischemic efficacy of nicorandil in comparison with isosorbide-5-mononitrate and isosorbide dinitrate: results from two multicenter, double-blind, randomized studies with stable coronary heart disease patients.
Topics: Adult; Aged; Blood Pressure; Coronary Disease; Double-Blind Method; Drug Administration Schedule; Exercise; Female; Heart Rate; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Potassium Channels; Vasodilator Agents | 1992 |
44 other study(ies) available for nicorandil and Coronary Heart Disease
| Article | Year |
|---|---|
Clinical Implications of Nicorandil Combined with Trimetazidine in Patients with Coronary Heart Disease: A Real-World Observational Study.
Topics: Adult; Angina Pectoris; Coronary Disease; Humans; Nicorandil; Retrospective Studies; Trimetazidine | 2022 |
Effects of intravenous bolus injection of nicorandil on renal artery flow velocity assessed by color Doppler ultrasound.
Topics: Aged; Blood Flow Velocity; Coronary Disease; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nicorandil; Nitroglycerin; Renal Artery; Ultrasonography, Doppler, Color; Vasodilation; Vasodilator Agents | 2017 |
Oral nicorandil for prevention of cardiac death in hemodialysis patients without obstructive coronary artery disease: a propensity-matched patient analysis.
Topics: Administration, Oral; Aged; Cardiovascular Agents; Coronary Angiography; Coronary Disease; Death, Sudden, Cardiac; Drug Evaluation; Female; Follow-Up Studies; Heart Failure; Humans; Insulin Resistance; Kaplan-Meier Estimate; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Nicorandil; Proportional Hazards Models; Renal Dialysis; Retrospective Studies; Tomography, Emission-Computed, Single-Photon | 2011 |
Haemodynamic and electrocardiographic consequences of severe nicorandil toxicity.
Topics: Adult; Blood Pressure; Coronary Disease; Electrocardiography; Humans; Hypotension; Myocardial Ischemia; Nicorandil; Vasodilator Agents | 2003 |
The changes of fractional flow reserve after intracoronary nitrate and Nicorandil injection in coronary artery ectasia.
Topics: Blood Flow Velocity; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vessels; Diagnosis, Differential; Dilatation, Pathologic; Female; Follow-Up Studies; Humans; Injections, Intra-Arterial; Isosorbide Dinitrate; Male; Middle Aged; Nicorandil; Vasodilator Agents | 2006 |
Coronary slow flow phenomenon caused by contrast-induced microvascular spasm.
Topics: Contrast Media; Coronary Angiography; Coronary Disease; Coronary Vasospasm; Coronary Vessels; Humans; Male; Microcirculation; Middle Aged; Nicorandil; Regional Blood Flow; Vasodilator Agents | 2007 |
[Efficacy of nicorandil (SG-75), a substance with nitro-properties and long-term effects in coronary patients: improvement of LV-function and wall motility without pacing-induced myocardial ischemia].
Topics: Aged; Angiography; Cardiac Pacing, Artificial; Coronary Disease; Heart Ventricles; Hemodynamics; Humans; Middle Aged; Myocardial Contraction; Niacinamide; Nicorandil; Oxygen Consumption | 1982 |
Nicorandil attenuates myocardial acidosis during coronary occlusion in dogs.
Topics: Acidosis; Animals; Coronary Disease; Dogs; Female; Heart Diseases; Male; Niacinamide; Nicorandil; Vasodilator Agents | 1984 |
Effects of nicorandil, a new antianginal agent, and nifedipine on collateral blood flow in a chronic coronary occlusion model.
Topics: Animals; Collateral Circulation; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Female; Hemodynamics; Male; Niacinamide; Nicorandil; Nifedipine; Vasodilator Agents | 1984 |
Nicorandil improves ischemic changes in epicardial ECG during short-term coronary occlusion by opening ATP-sensitive potassium channels in pigs.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Electrocardiography; Female; Hemodynamics; In Vitro Techniques; Male; Niacinamide; Nicorandil; Pericardium; Potassium Channels; Swine | 1997 |
[Oral aphthae induced by nicorandil. Anatomopathologic aspects. Apropos of a case].
Topics: Aged; Coronary Disease; Endothelium, Vascular; Epithelium; Humans; Immunoglobulin Light Chains; Leukocytes; Male; Nicorandil; Sialadenitis; Stomatitis, Aphthous; Vasodilator Agents | 1998 |
Images in cardiology Coronary artery spasm.
Topics: Aged; Anticoagulants; Coronary Angiography; Coronary Disease; Electrocardiography; Female; Humans; Nicorandil; Nitroglycerin; Thrombolytic Therapy; Tissue Plasminogen Activator; Vasodilator Agents | 1999 |
[The role of ischemic preconditioning in off-pump CABG: is it really necessary to accomplish scrupulous ischemic preconditioning?].
Topics: Allopurinol; Coronary Artery Bypass; Coronary Disease; Humans; Ischemic Preconditioning, Myocardial; Minimally Invasive Surgical Procedures; Myocardium; Nicorandil | 2001 |
Effects of administration of nicorandil or bimakalim prior to and during ischemia or reperfusion on survival rate, ischemia/reperfusion-induced arrhythmias and infarct size in anesthetized rabbits.
Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Blood Gas Analysis; Coronary Disease; Decanoic Acids; Dihydropyridines; Drug Combinations; Hemodynamics; Hydroxy Acids; Male; Myocardial Ischemia; Nicorandil; Potassium Channels; Rabbits; Reperfusion Injury; Survival Rate | 2001 |
Cardiovascular news.
Topics: Acetanilides; Angina, Unstable; Anti-Arrhythmia Agents; Calcium Channel Blockers; Coronary Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fibrinolytic Agents; Fondaparinux; Humans; Hydantoins; Imidazoles; Imidazolidines; Multicenter Studies as Topic; Myocardial Infarction; Nicorandil; Piperazines; Polysaccharides; Randomized Controlled Trials as Topic; Ranolazine; Treatment Outcome | 2001 |
Effect of an orally active Na+/H+ exchange inhibitor, SMP-300, on experimental angina and myocardial infarction models in rats.
Topics: Administration, Oral; Angina Pectoris; Animals; Azocines; Coronary Disease; Electrocardiography; Isoproterenol; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nicorandil; Nifedipine; Propranolol; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sodium-Hydrogen Exchangers; Vasodilator Agents; Vasopressins | 2002 |
Nicorandil and cardiovascular performance in patients with coronary artery disease.
Topics: Administration, Sublingual; Coronary Circulation; Coronary Disease; Female; Hemodynamics; Humans; Isosorbide Dinitrate; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilation; Vasodilator Agents; Ventricular Function, Left | 1992 |
Suppression of sympathetic nervous system activity by nicorandil during exercise.
Topics: Adult; Aged; Coronary Disease; Depression, Chemical; Electroencephalography; Epinephrine; Exercise; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Norepinephrine; Sympathetic Nervous System | 1992 |
Nicorandil improves postischemic contractile function independently of direct myocardial effects.
Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Dogs; Heart Function Tests; Heart Rate; In Vitro Techniques; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardium; Niacinamide; Nicorandil; Perfusion; Pyrroles; Rats; Rats, Inbred Strains | 1990 |
Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Heart; Kinetics; Male; Myocardial Contraction; Myocardial Reperfusion; Niacinamide; Nicorandil; Potassium; Potassium Channels; Rats; Rats, Inbred Strains; Ventricular Function, Left | 1991 |
Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart.
Topics: Animals; Coronary Disease; Cytosol; Glyburide; Heart Rate; In Vitro Techniques; Male; Myocardium; Niacinamide; Nicorandil; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Vasodilator Agents | 1991 |
Angiographic response to a vasodilating drug, nicorandil, in patients with coronary artery disease.
Topics: Administration, Sublingual; Adult; Aged; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Time Factors; Vasodilation; Vasodilator Agents | 1990 |
[Clinical electrophysiological effects of nicorandil on the conduction system in humans].
Topics: Coronary Disease; Electrophysiology; Female; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilator Agents | 1990 |
[Effect of nicorandil on coronary circulation in ischemic region].
Topics: Animals; Blood Viscosity; Coronary Circulation; Coronary Disease; Dogs; Female; Hemodynamics; Infusions, Intra-Arterial; Male; Niacinamide; Nicorandil; Vascular Resistance; Vasodilator Agents | 1990 |
Beneficial effects of nicorandil on cardiovascular hemodynamics and left ventricular function.
Topics: Angina Pectoris; Cardiac Catheterization; Cardiac Pacing, Artificial; Coronary Disease; Female; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilator Agents | 1987 |
Effects of nicorandil on coronary hemodynamics in ischemic heart disease: comparison with nitroglycerin, nifedipine, and propranolol.
Topics: Adult; Aged; Cardiac Pacing, Artificial; Coronary Circulation; Coronary Disease; Hemodynamics; Humans; Lactates; Lactic Acid; Middle Aged; Myocardium; Niacinamide; Nicorandil; Nifedipine; Nitroglycerin; Norepinephrine; Oxygen Consumption; Propranolol; Vasodilator Agents | 1987 |
Effects of nicorandil on coronary circulation in patients with ischemic heart disease: comparison with nitroglycerin.
Topics: Coronary Circulation; Coronary Disease; Coronary Vasospasm; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Nitroglycerin; Vasodilation; Vasodilator Agents | 1987 |
Comparative effects of nicorandil, nitroglycerin, nicotinic acid, and SG-86 on the metabolic status and functional recovery of the ischemic-reperfused myocardium.
Topics: Animals; Coronary Circulation; Coronary Disease; Dogs; Fatty Acids, Nonesterified; Female; Glucose; Heart; Hemodynamics; Male; Myocardial Contraction; Myocardium; Niacin; Niacinamide; Nicorandil; Nitroglycerin; Perfusion; Vasodilator Agents | 1987 |
Effects of nicorandil and other antianginal drugs on myocardial pH in the ischemic dog heart.
Topics: Acidosis; Animals; Coronary Disease; Diltiazem; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Propranolol; Sotalol; Vasodilator Agents | 1987 |
Examination of the direct effects of nicorandil, verapamil, propranolol, and nitroglycerin on the hypoxic canine myocardium.
Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; In Vitro Techniques; Male; Myocardium; Niacinamide; Nicorandil; Nitroglycerin; Perfusion; Propranolol; Vasodilator Agents; Verapamil | 1987 |
Reduction of size of myocardial infarction with nicorandil, a new antianginal drug, after coronary artery occlusion in dogs.
Topics: Animals; Coronary Disease; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Niacinamide; Nicorandil; Vasodilator Agents | 1988 |
Effects of nicorandil and nipradilol on ischemic myocardium in perfused rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Heart; In Vitro Techniques; Lactates; Male; Niacinamide; Nicorandil; Phosphocreatine; Propanolamines; Rats; Rats, Inbred Strains | 1989 |
Acute hemodynamic effects of single-dose nicorandil in coronary artery disease.
Topics: Administration, Oral; Administration, Sublingual; Adult; Coronary Disease; Female; Hemodynamics; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilator Agents | 1989 |
Effects of intravenous administration of nicorandil on cardiovascular hemodynamics and left ventricular function.
Topics: Aged; Coronary Disease; Female; Hemodynamics; Humans; Injections, Intravenous; Male; Middle Aged; Myocardial Contraction; Niacinamide; Nicorandil; Stroke Volume; Vasodilator Agents | 1989 |
Coronary vasodilatory action after nicorandil: a quantitative angiographic study.
Topics: Administration, Sublingual; Adult; Aged; Angiography; Coronary Angiography; Coronary Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Niacinamide; Nicorandil; Vasodilation; Vasodilator Agents | 1989 |
Assessment of the antiarrhythmic activity of nicorandil during myocardial ischemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Coronary Circulation; Coronary Disease; Electrocardiography; In Vitro Techniques; Lactates; Myocardial Reperfusion Injury; Niacinamide; Nicorandil; Rats; Rats, Inbred Strains; Vasodilator Agents | 1989 |
Protective effect of nicorandil on postischemic function and tissue adenine nucleotides following a brief period of low-flow global ischemia in the isolated perfused rat heart.
Topics: Adenine Nucleotides; Animals; Coronary Disease; Epoprostenol; Heart; Heart Function Tests; In Vitro Techniques; Male; Monoamine Oxidase Inhibitors; Myocardium; Niacinamide; Nicorandil; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Nicorandil and cardiovascular performance in anaesthetized pigs with a concentric coronary artery stenosis.
Topics: Anesthesia; Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Conduction System; Heart Function Tests; Hemodynamics; Microspheres; Niacinamide; Nicorandil; Oxygen Consumption; Regional Blood Flow; Swine | 1989 |
Protection of acute ischemic myocardial injury by pharmacological intervention.
Topics: Adenosine Triphosphatases; Adrenergic alpha-Antagonists; Animals; Calcium; Calcium-Transporting ATPases; Coenzymes; Coronary Disease; Diltiazem; Dogs; Myocardium; Niacinamide; Nicorandil; Quinazolines; Sarcoplasmic Reticulum; Ubiquinone; Vasodilator Agents | 1989 |
Recovery of contractile function in post-ischaemic reperfused myocardium of conscious dogs: influence of nicorandil, a new antianginal agent.
Topics: Animals; Blood Pressure; Coronary Disease; Dogs; Female; Heart; Heart Rate; Male; Myocardial Contraction; Niacinamide; Nicorandil; Perfusion; Vasodilator Agents | 1986 |
Salutary action of nicorandil, a new antianginal drug, on myocardial metabolism during ischemia and on postischemic function in a canine preparation of brief, repetitive coronary artery occlusions: comparison with isosorbide dinitrate.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Energy Metabolism; Fatty Acids, Nonesterified; Female; Glucose; Hemodynamics; Isosorbide Dinitrate; Male; Myocardium; Niacinamide; Nicorandil; Oxygen; Recurrence | 1987 |
Coronary vasodilatory action after a single dose of nicorandil.
Topics: Adult; Aged; Blood Pressure; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vessels; Female; Humans; Male; Middle Aged; Myocardium; Niacinamide; Nicorandil; Oxygen Consumption; Vascular Resistance; Vasodilation; Vasodilator Agents | 1988 |
Experimental studies on ischemic injury and reperfusion injury to the cardiac sarcoplasmic reticulum--the myocardial protective effect of nicorandil.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Cardioplegic Solutions; Cardiopulmonary Bypass; Coronary Disease; Dogs; Heart Rate; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Niacinamide; Nicorandil; Sarcoplasmic Reticulum | 1988 |
Effectiveness of nicorandil in the preservation of myocardium stressed by transient ischemia and its influence on cardiac metabolism during coronary artery occlusion with subsequent reperfusion: a comparison with isosorbide dinitrate.
Topics: Animals; Coronary Disease; Coronary Vessels; Dogs; Fatty Acids, Nonesterified; Glucose; Heart; Hemodynamics; Isosorbide Dinitrate; Lactates; Lactic Acid; Ligation; Myocardium; Niacinamide; Nicorandil; Perfusion | 1985 |