nicorandil has been researched along with Alloxan Diabetes in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.88) | 18.7374 |
| 1990's | 2 (11.76) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 8 (47.06) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, B; Lian, Z; Ren, J; Wan, Q; Wang, Y; Xia, Z; Yang, Y; Yao, X; Zhou, C | 1 |
| Caudillo-Cisneros, C; Márquez-Gamiño, S; Melchor-Moreno, MT; Montoya-Pérez, R; Sánchez-Duarte, E; Sánchez-Duarte, S; Sotelo-Barroso, F; Vera-Delgado, KS; Villicaña-Gómez, EA | 1 |
| Ayijiang, J; Chen, LN; Gong, X; Li, YN; Liu, X; Xing, T; Yan, WH; Yang, YX; Yu, Y; Zhang, CX; Zhang, M | 1 |
| Li, X; Ling, M; Liu, C; Wang, Z; Xing, Y; Zhang, H; Zhang, M | 1 |
| An, F; Jin, T; Li, X; Liu, D; Liu, M; Pan, J; Tian, J; Wang, X; Zhang, M | 1 |
| Li, Y; Liu, L; Liu, Y; Qi, B; Wang, Z; Wu, Q | 1 |
| Chen, YD; Li, B; Ma, Q; Tian, F; Zhang, Y; Zhang, YQ; Zhou, Y | 1 |
| Chen, Y; Dai, R; Deng, Y; Lao, X; Li, Y; Meng, W; Sheng, L; Wu, C | 1 |
| Aizawa, K; Ishizuka, N; Serizawa, K; Tashiro, Y; Yogo, K | 1 |
| Johnson, RJ; Kitagawa, W; Klawitter, J; Lanaspa, MA; Makino, H; Mathieson, PW; Miyazaki, M; Nakagawa, T; Rivard, CJ; Saleem, MA; Schreiner, GF; Tanabe, K | 1 |
| Chan, P; Cheng, JT; Liu, IM; Tzeng, TF; Wong, KL; Yang, TL | 1 |
| Ishikawa, S; Kakehashi, A; Kasono, K; Kawakami, M; Kinoshita, N; Kuroki, M; Namai, K; Ohno, R; Tamemoto, H; Ueba, H; Yasu, T | 1 |
| Kasiviswanath, R; Kumar, KE; Ramesh, A | 1 |
| Fujiwara, K; Hayashi, R; Itoh, M; Kobayashi, T; Mano, T; Nagasaka, A; Nakagawa, H; Nakai, A; Nakano, I; Shinohara, R; Tsugawa, T; Uchimura, K; Watanabe, F | 1 |
| Kamata, K; Kasuya, Y; Miyata, N; Otomo, S; Tsuchida, K; Yamaura, H | 1 |
| Matsuzaki, T; Sakanashi, M | 1 |
| Kamata, K; Kasuya, Y; Miyata, N | 1 |
1 trial(s) available for nicorandil and Alloxan Diabetes
| Article | Year |
|---|---|
Protective effect of ischaemic postconditioning combined with nicorandil on myocardial ischaemia‒reperfusion injury in diabetic rats.
Topics: Animals; Creatine Kinase, MB Form; Diabetes Mellitus, Experimental; Heart Injuries; Ischemic Postconditioning; Myocardial Infarction; Myocardial Reperfusion Injury; Nicorandil; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Reactive Oxygen Species | 2022 |
16 other study(ies) available for nicorandil and Alloxan Diabetes
| Article | Year |
|---|---|
Nicorandil decreases oxidative stress in slow- and fast-twitch muscle fibers of diabetic rats by improving the glutathione system functioning.
Topics: Animals; Diabetes Mellitus, Experimental; Gene Expression Regulation; Glutathione; Lipid Peroxidation; Male; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Nicorandil; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Transcription, Genetic | 2021 |
[Nicorandil improves cognitive dysfunction in mice with streptozotocin-induced diabetes].
Topics: Animals; Blood Glucose; Cognitive Dysfunction; Diabetes Mellitus, Experimental; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Hippocampus; Insulin-Secreting Cells; Malondialdehyde; Mice; Mice, Inbred C57BL; Nicorandil; Streptozocin; Superoxide Dismutase | 2018 |
Myocardial Protective Effects of Nicorandil on Rats with Type 2 Diabetic Cardiomyopathy.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Disease Models, Animal; Heart; Male; Malondialdehyde; Myocardium; Nicorandil; Rats; Rats, Wistar; Superoxide Dismutase | 2018 |
Nicorandil alleviates apoptosis in diabetic cardiomyopathy through PI3K/Akt pathway.
Topics: Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Myocardium; Myocytes, Cardiac; Nicorandil; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Streptozocin | 2019 |
Nicorandil attenuates endothelial VCAM-1 expression via thioredoxin production in diabetic rats induced by streptozotocin.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Endothelial Cells; Fasting; Gene Expression Regulation; Immunohistochemistry; Male; Malondialdehyde; Nicorandil; Rats; Streptozocin; Superoxide Dismutase; Thioredoxins; Vascular Cell Adhesion Molecule-1 | 2014 |
Nicorandil attenuates carotid intimal hyperplasia after balloon catheter injury in diabetic rats.
Topics: Angioplasty, Balloon; Animals; Carotid Arteries; Carotid Artery Injuries; Cell Movement; Cell Proliferation; Diabetes Mellitus, Experimental; Endothelium, Vascular; Hyperplasia; Male; Muscle, Smooth, Vascular; Nicorandil; Rats, Sprague-Dawley | 2016 |
Hypoglycemic effect of Belamcanda chinensis leaf extract in normal and STZ-induced diabetic rats and its potential active faction.
Topics: Animals; Blood Glucose; Calcium; Calcium Channels; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Iridaceae; Male; Nicorandil; Nifedipine; Phytotherapy; Plant Extracts; Plant Leaves; Potassium; Potassium Channels; Rats; Rats, Wistar; Streptozocin | 2011 |
Nicorandil prevents endothelial dysfunction due to antioxidative effects via normalisation of NADPH oxidase and nitric oxide synthase in streptozotocin diabetic rats.
Topics: Acetophenones; Animals; Antioxidants; Cells, Cultured; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Femoral Artery; GTP Cyclohydrolase; Humans; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nicorandil; Nitric Oxide Synthase Type III; Oxidative Stress; Protein Multimerization; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spin Labels; Time Factors; Ultrasonography; Vasodilation; Vasodilator Agents | 2011 |
Nicorandil as a novel therapy for advanced diabetic nephropathy in the eNOS-deficient mouse.
Topics: Animals; Antioxidants; Apoptosis; Blood Pressure; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Disease Progression; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nicorandil; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Oxidative Stress; Podocytes; Reactive Oxygen Species; Severity of Illness Index; Streptozocin | 2012 |
Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperglycemia; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nicorandil; Nifedipine; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; RNA, Messenger; Saralasin; Tetrazoles; Valine; Valsartan | 2003 |
Nicorandil improves diabetes and rat islet beta-cell damage induced by streptozotocin in vivo and in vitro.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Free Radical Scavengers; Glucagon; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Nicorandil; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred BN; Reactive Oxygen Species; Superoxides; Vasodilator Agents | 2004 |
Hypoglycemic and antihyperglycemic effect of Gmelina asiatica LINN. in normal and in alloxan induced diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Drug Interactions; Female; Glucose Tolerance Test; Hypoglycemic Agents; Lamiaceae; Male; Mice; Nicorandil; Plant Extracts; Rats; Rats, Sprague-Dawley; Tolbutamide; Verbenaceae | 2005 |
Scavenging effect of nicorandil on free radicals and lipid peroxide in streptozotocin-induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Free Radical Scavengers; Isoquinolines; Kidney; Lipid Peroxides; Liver; Male; Nicorandil; Osmolar Concentration; Papillary Muscles; Potassium Channels; Rats; Rats, Wistar; Reactive Oxygen Species; Superoxide Dismutase; Xanthine Oxidase | 2000 |
Changes in responsiveness of the aorta to vasorelaxant agents in genetically diabetic rats: a study in WBN/Kob rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Colforsin; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, Vascular; Isoproterenol; Muscle Relaxation; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Pyrroles; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Vasodilator Agents | 1992 |
Comparison of the development of tolerance to nitroglycerin in aortic preparations isolated from non-diabetic and diabetic rats.
Topics: Acetylcysteine; Animals; Aorta, Thoracic; Blood Glucose; Culture Techniques; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Dose-Response Relationship, Drug; Drug Tolerance; Glycated Hemoglobin; Male; Muscle, Smooth, Vascular; Niacinamide; Nicorandil; Nitroglycerin; Norepinephrine; Rats; Rats, Inbred Strains; Vasodilation; Vasodilator Agents | 1992 |
Functional changes in potassium channels in aortas from rats with streptozotocin-induced diabetes.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Blood Glucose; Cromakalim; Diabetes Mellitus, Experimental; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Niacinamide; Nicorandil; Norepinephrine; Parasympatholytics; Potassium Channels; Pyrroles; Rats; Rats, Inbred Strains | 1989 |