niclosamide has been researched along with Zika Virus Infection in 5 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Zika Virus Infection: A viral disease transmitted by the bite of AEDES mosquitoes infected with ZIKA VIRUS. Its mild DENGUE-like symptoms include fever, rash, headaches and ARTHRALGIA. The viral infection during pregnancy, in rare cases, is associated with congenital brain and ocular abnormalities, called Congenital Zika Syndrome, including MICROCEPHALY and may also lead to GUILLAIN-BARRE SYNDROME.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we screened a small library of niclosamide derivatives and identified a new analogue with improved pharmacokinetic properties." | 5.56 | JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both ( Butler, D; Chen, H; D'Brant, L; Fan, X; Hu, S; Koetzner, CA; Kramer, LD; Kuo, L; Lang, Y; Li, H; Li, Z; Rugenstein, N; Samrat, SK; Tharappel, AM; Trudeau, N; Xu, J; Zhang, J; Zhang, QY; Zhou, J, 2020) |
| " Here, we screened a small library of niclosamide derivatives and identified a new analogue with improved pharmacokinetic properties." | 1.56 | JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both ( Butler, D; Chen, H; D'Brant, L; Fan, X; Hu, S; Koetzner, CA; Kramer, LD; Kuo, L; Lang, Y; Li, H; Li, Z; Rugenstein, N; Samrat, SK; Tharappel, AM; Trudeau, N; Xu, J; Zhang, J; Zhang, QY; Zhou, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 2 |
| Nath, A | 1 |
| Yang, W | 1 |
| Liu, LB | 1 |
| Liu, FL | 1 |
| Wu, YH | 1 |
| Zhen, ZD | 1 |
| Fan, DY | 1 |
| Sheng, ZY | 1 |
| Song, ZR | 1 |
| Chang, JT | 1 |
| Zheng, YT | 1 |
| An, J | 1 |
| Wang, PG | 1 |
| Huang, Y | 1 |
| Li, Q | 1 |
| Kang, L | 1 |
| Li, B | 1 |
| Ye, H | 1 |
| Duan, X | 1 |
| Xie, H | 1 |
| Jiang, M | 1 |
| Li, S | 1 |
| Zhu, Y | 1 |
| Tan, Q | 1 |
| Chen, L | 1 |
| Li, Z | 1 |
| Xu, J | 1 |
| Lang, Y | 1 |
| Fan, X | 1 |
| Kuo, L | 1 |
| D'Brant, L | 1 |
| Hu, S | 1 |
| Samrat, SK | 1 |
| Trudeau, N | 1 |
| Tharappel, AM | 1 |
| Rugenstein, N | 1 |
| Koetzner, CA | 1 |
| Zhang, J | 1 |
| Chen, H | 1 |
| Kramer, LD | 1 |
| Butler, D | 1 |
| Zhang, QY | 1 |
| Zhou, J | 1 |
| Li, H | 1 |
| Xu, M | 1 |
| Lee, EM | 1 |
| Wen, Z | 1 |
| Cheng, Y | 1 |
| Huang, WK | 1 |
| Qian, X | 1 |
| Tcw, J | 1 |
| Kouznetsova, J | 1 |
| Ogden, SC | 1 |
| Hammack, C | 1 |
| Jacob, F | 1 |
| Nguyen, HN | 1 |
| Itkin, M | 1 |
| Hanna, C | 1 |
| Shinn, P | 1 |
| Allen, C | 1 |
| Michael, SG | 1 |
| Huang, W | 1 |
| Christian, KM | 1 |
| Goate, A | 1 |
| Brennand, KJ | 1 |
| Huang, R | 1 |
| Xia, M | 1 |
| Ming, GL | 1 |
| Zheng, W | 1 |
| Song, H | 1 |
| Tang, H | 1 |
5 other studies available for niclosamide and Zika Virus Infection
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation.
Topics: Animals; Complement Activation; Male; Mice; Niclosamide; Sequence Analysis, RNA; Zika Virus; Zika Vi | 2023 |
Mitophagy Activation Targeting PINK1 Is an Effective Treatment to Inhibit Zika Virus Replication.
Topics: Animals; Mice; Mitophagy; Niclosamide; Protein Kinases; Ubiquitin; Zika Virus; Zika Virus Infection | 2023 |
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both
Topics: Animals; Flavivirus; Humans; Niclosamide; Viral Nonstructural Proteins; Zika Virus; Zika Virus Infec | 2020 |
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Topics: Astrocytes; Brain; Caspase 3; Caspase Inhibitors; Cell Death; Cell Line; Drug Repositioning; Humans; | 2016 |