Page last updated: 2024-11-01

niclosamide and Pancreatic Neoplasms

niclosamide has been researched along with Pancreatic Neoplasms in 2 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's2 (100.00)2.80

Authors

AuthorsStudies
Guo, Y1
Zhu, H1
Xiao, Y1
Guo, H1
Lin, M1
Yuan, Z1
Yang, X1
Huang, Y1
Zhang, Q1
Bai, Y1
Kang, HW1
Kim, JH1
Lee, DE1
Lee, YS1
Kim, MJ1
Kim, HS1
Fang, S1
Lee, BE1
Lee, KJ1
Yoo, J1
Kim, HJ1
Park, JS1

Other Studies

2 other studies available for niclosamide and Pancreatic Neoplasms

ArticleYear
The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression.
    Cell death & disease, 2022, 02-03, Volume: 13, Issue:2

    Topics: Animals; Anthelmintics; beta Catenin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabi

2022
The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression.
    Cell death & disease, 2022, 02-03, Volume: 13, Issue:2

    Topics: Animals; Anthelmintics; beta Catenin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabi

2022
The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression.
    Cell death & disease, 2022, 02-03, Volume: 13, Issue:2

    Topics: Animals; Anthelmintics; beta Catenin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabi

2022
The anthelmintic drug niclosamide induces GSK-β-mediated β-catenin degradation to potentiate gemcitabine activity, reduce immune evasion ability and suppress pancreatic cancer progression.
    Cell death & disease, 2022, 02-03, Volume: 13, Issue:2

    Topics: Animals; Anthelmintics; beta Catenin; Cell Line, Tumor; Cell Proliferation; Deoxycytidine; Gemcitabi

2022
Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: Apoptosis; beta Catenin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gemcita

2023
Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: Apoptosis; beta Catenin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gemcita

2023
Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: Apoptosis; beta Catenin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gemcita

2023
Combination therapy of niclosamide with gemcitabine inhibited cell proliferation and apoptosis via Wnt/β-catenin/c-Myc signaling pathway by inducing β-catenin ubiquitination in pancreatic cancer.
    Cancer biology & therapy, 2023, 12-31, Volume: 24, Issue:1

    Topics: Apoptosis; beta Catenin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Gemcita

2023