niclosamide has been researched along with Osteosarcoma in 3 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteosarcoma is a highly common malignant bone tumor." | 5.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
| "Niclosamide was found to induce the arrest of S and G2/M phase in U2OS cells and G2/M in MG-63 cells." | 5.42 | Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest. ( Li, Z; Qi, B; Sun, S; Wang, W; Yu, A; Yu, Y, 2015) |
| "Osteosarcoma is a highly common malignant bone tumor." | 1.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
| "Niclosamide was found to induce the arrest of S and G2/M phase in U2OS cells and G2/M in MG-63 cells." | 1.42 | Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest. ( Li, Z; Qi, B; Sun, S; Wang, W; Yu, A; Yu, Y, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, LT | 1 |
| Lin, CW | 1 |
| Lu, KH | 1 |
| Hsieh, YH | 1 |
| Yeh, CB | 1 |
| Yang, SF | 1 |
| Yang, JS | 1 |
| Li, Z | 1 |
| Yu, Y | 1 |
| Sun, S | 1 |
| Qi, B | 1 |
| Wang, W | 1 |
| Yu, A | 1 |
| Liao, Z | 1 |
| Nan, G | 1 |
| Yan, Z | 1 |
| Zeng, L | 1 |
| Deng, Y | 1 |
| Ye, J | 1 |
| Zhang, Z | 1 |
| Qiao, M | 1 |
| Li, R | 1 |
| Denduluri, S | 1 |
| Wang, J | 1 |
| Wei, Q | 1 |
| Geng, N | 1 |
| Zhao, L | 1 |
| Lu, S | 1 |
| Wang, X | 1 |
| Zhou, G | 1 |
| Luu, HH | 1 |
| Haydon, RC | 1 |
| He, TC | 1 |
| Wang, Z | 1 |
3 other studies available for niclosamide and Osteosarcoma
| Article | Year |
|---|---|
Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.
Topics: Cell Death; Cell Line, Tumor; Cell Movement; Extracellular Matrix Proteins; Gene Knockdown Technique | 2022 |
Niclosamide inhibits the proliferation of human osteosarcoma cell lines by inducing apoptosis and cell cycle arrest.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Bone Neoplasms; Cell Cycle Checkpoi | 2015 |
The Anthelmintic Drug Niclosamide Inhibits the Proliferative Activity of Human Osteosarcoma Cells by Targeting Multiple Signal Pathways.
Topics: Animals; Anthelmintics; Antineoplastic Agents; Biomarkers, Tumor; Bone Neoplasms; Cell Line, Tumor; | 2015 |