niclosamide has been researched along with Muscular Atrophy in 2 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niclosamide treatment also inhibited myogenesis in muscle precursor cells, enhanced the expression of myoblast markers Pax7 and Myf5, and downregulated the expression of differentiation markers MyoD, MyoG and Myh2." | 1.62 | Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy. ( Jung, DW; Kim, HJ; Kim, SW; Lee, JH; Lee, SH; Williams, DR, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, HJ | 1 |
| Lee, JH | 1 |
| Kim, SW | 1 |
| Lee, SH | 1 |
| Jung, DW | 1 |
| Williams, DR | 1 |
| Cai, Y | 1 |
| Zhan, H | 1 |
| Weng, W | 1 |
| Wang, Y | 1 |
| Han, P | 1 |
| Yu, X | 1 |
| Shao, M | 1 |
| Sun, H | 1 |
2 other studies available for niclosamide and Muscular Atrophy
| Article | Year |
|---|---|
Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy.
Topics: A549 Cells; Animals; Cachexia; Cell Line, Tumor; Drug Repositioning; HCT116 Cells; Humans; Inhibitor | 2021 |
Niclosamide ethanolamine ameliorates diabetes-related muscle wasting by inhibiting autophagy.
Topics: Animals; Autophagy; Diabetes Mellitus; Ethanolamine; Ethanolamines; Mice; Muscle, Skeletal; Muscles; | 2021 |