Page last updated: 2024-11-01

niclosamide and Malignant Melanoma

niclosamide has been researched along with Malignant Melanoma in 4 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Research Excerpts

ExcerptRelevanceReference
"Niclosamide (NCL) is an FDA-approved anthelmintic drug and is reported to have strong anti-cancer properties against various solid and liquid tumors."5.91Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells. ( Godugu, C; Nagula, S; Pooladanda, V; Thatikonda, S; Tokala, R, 2023)
"Malignant melanoma is one of the most aggressive and lethal skin cancer."5.91Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation. ( Ding, C; Ge, X; Jiang, J; Li, S; Li, Y; Qiao, Y; Wang, D; Wang, M; Wang, Y; Zheng, X, 2023)
"Melanoma is the most malignant form of skin cancer across the globe."5.72Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation. ( Bagasariya, D; Bala Singh, S; Charankumar, K; Famta, P; Fernandes, V; Kumar Khatri, D; Shah, S; Srivastava, S, 2022)
"Niclosamide (NCL) is an FDA-approved anthelmintic drug and is reported to have strong anti-cancer properties against various solid and liquid tumors."1.91Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells. ( Godugu, C; Nagula, S; Pooladanda, V; Thatikonda, S; Tokala, R, 2023)
"Malignant melanoma is one of the most aggressive and lethal skin cancer."1.91Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation. ( Ding, C; Ge, X; Jiang, J; Li, S; Li, Y; Qiao, Y; Wang, D; Wang, M; Wang, Y; Zheng, X, 2023)
"Melanoma is the most malignant form of skin cancer across the globe."1.72Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation. ( Bagasariya, D; Bala Singh, S; Charankumar, K; Famta, P; Fernandes, V; Kumar Khatri, D; Shah, S; Srivastava, S, 2022)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Shah, S1
Famta, P1
Fernandes, V1
Bagasariya, D1
Charankumar, K1
Kumar Khatri, D1
Bala Singh, S1
Srivastava, S1
Thatikonda, S1
Pooladanda, V1
Tokala, R1
Nagula, S1
Godugu, C1
Li, S1
Wang, D1
Zheng, X1
Li, Y1
Ding, C1
Wang, M1
Ge, X1
Jiang, J1
Qiao, Y1
Wang, Y1
Zhou, J1
Jin, B1
Jin, Y1
Liu, Y1
Pan, J1

Other Studies

4 other studies available for niclosamide and Malignant Melanoma

ArticleYear
Quality by design steered development of Niclosamide loaded liposomal thermogel for Melanoma: In vitro and Ex vivo evaluation.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2022, Volume: 180

    Topics: Administration, Cutaneous; Humans; Liposomes; Melanoma; Niclosamide; Skin Neoplasms; Tumor Microenvi

2022
Niclosamide inhibits epithelial-mesenchymal transition with apoptosis induction in BRAF/ NRAS mutated metastatic melanoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2023, Volume: 89

    Topics: Apoptosis; Cell Line, Tumor; Epithelial-Mesenchymal Transition; GTP Phosphohydrolases; Humans; Melan

2023
Combination of niclosamide and quinacrine inactivates Akt/HK2/Cyclin D1 axis mediated by glucose deprivation towards the inhibition of melanoma cell proliferation.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 163

    Topics: Cell Line, Tumor; Cell Proliferation; Cyclin D1; Glucose; Humans; Melanoma; Niclosamide; Proto-Oncog

2023
The antihelminthic drug niclosamide effectively inhibits the malignant phenotypes of uveal melanoma
    Theranostics, 2017, Volume: 7, Issue:6

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dise

2017