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niclosamide and Lupus Erythematosus, Systemic

niclosamide has been researched along with Lupus Erythematosus, Systemic in 1 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Lupus Erythematosus, Systemic: A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.

Research Excerpts

ExcerptRelevanceReference
"Niclosamide treatment greatly improved proteinuria, anti-dsDNA antibody levels, immunoglobulin subclass titers, histology of lupus nephritis, and C3 deposition in MRL/lpr and R848-induced mice."1.62Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3. ( Cho, ML; Hong, SM; Jang, SG; Kim, MJ; Kwok, SK; Lee, J; Park, SH; Song, YS, 2021)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Jang, SG1
Lee, J1
Hong, SM1
Song, YS1
Kim, MJ1
Kwok, SK1
Cho, ML1
Park, SH1

Other Studies

1 other study available for niclosamide and Lupus Erythematosus, Systemic

ArticleYear
Niclosamide suppresses the expansion of follicular helper T cells and alleviates disease severity in two murine models of lupus via STAT3.
    Journal of translational medicine, 2021, 02-25, Volume: 19, Issue:1

    Topics: Animals; Disease Models, Animal; Lupus Erythematosus, Systemic; Mice; Mice, Inbred C57BL; Mice, Inbr

2021