niclosamide has been researched along with Invasiveness, Neoplasm in 10 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Osteosarcoma is a highly common malignant bone tumor." | 5.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
| "The potency of niclosamide on breast cancer was assessed in vitro and in vivo." | 5.40 | The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014) |
| "Osteosarcoma is a highly common malignant bone tumor." | 1.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
| "The morbidity of thyroid cancer has been rising obviously throughout the world during the past years." | 1.46 | Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro. ( An, Z; Li, S; Li, Y; Wang, C; Wang, T; Wang, X; Xie, Y; Ye, T; Yu, K; Zhang, M, 2017) |
| "The potency of niclosamide on breast cancer was assessed in vitro and in vivo." | 1.40 | The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014) |
| "Metastasis formation in colon cancer severely reduces the survival rate in patients." | 1.37 | Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. ( Fichtner, I; Kobelt, D; Lemm, M; Sack, U; Schlag, PM; Scudiero, D; Selby, M; Shoemaker, RH; Stein, U; Walther, W, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeh, LT | 1 |
| Lin, CW | 1 |
| Lu, KH | 1 |
| Hsieh, YH | 1 |
| Yeh, CB | 2 |
| Yang, SF | 2 |
| Yang, JS | 1 |
| Hilfenhaus, G | 1 |
| Mompeón, A | 1 |
| Freshman, J | 1 |
| Prajapati, DP | 1 |
| Hernandez, G | 1 |
| Freitas, VM | 1 |
| Ma, F | 1 |
| Langenbacher, AD | 1 |
| Mirkov, S | 1 |
| Song, D | 1 |
| Cho, BK | 1 |
| Goo, YA | 1 |
| Pellegrini, M | 1 |
| Chen, JN | 1 |
| Damoiseaux, R | 1 |
| Iruela-Arispe, ML | 1 |
| Yu, K | 1 |
| Wang, T | 1 |
| Li, Y | 1 |
| Wang, C | 2 |
| Wang, X | 1 |
| Zhang, M | 1 |
| Xie, Y | 1 |
| Li, S | 1 |
| An, Z | 1 |
| Ye, T | 2 |
| Chien, MH | 1 |
| Ho, YC | 1 |
| Yang, YC | 1 |
| Lai, SY | 1 |
| Chen, WS | 1 |
| Chen, MJ | 1 |
| Yuquan, B | 1 |
| Hexiao, T | 1 |
| Laiyi, W | 1 |
| Gaofeng, P | 1 |
| Xuefeng, Z | 1 |
| Ming, X | 1 |
| Yanhong, W | 1 |
| Li, Z | 1 |
| Jinping, Z | 1 |
| Xiong, Y | 1 |
| Yan, Y | 1 |
| Xia, Y | 1 |
| Song, X | 1 |
| Liu, L | 2 |
| Li, D | 1 |
| Wang, N | 1 |
| Zhang, L | 1 |
| Zhu, Y | 1 |
| Zeng, J | 1 |
| Wei, Y | 1 |
| Yu, L | 1 |
| Liu, J | 1 |
| Chen, X | 1 |
| Ward, T | 1 |
| Pegram, M | 1 |
| Shen, K | 1 |
| Stewart, RL | 1 |
| Carpenter, BL | 1 |
| West, DS | 1 |
| Knifley, T | 1 |
| Weiss, HL | 1 |
| Gal, TS | 1 |
| Durbin, EB | 1 |
| Arnold, SM | 1 |
| O'Connor, KL | 1 |
| Chen, M | 1 |
| Helfman, DM | 1 |
| Sack, U | 1 |
| Walther, W | 1 |
| Scudiero, D | 1 |
| Selby, M | 1 |
| Kobelt, D | 1 |
| Lemm, M | 1 |
| Fichtner, I | 1 |
| Schlag, PM | 1 |
| Shoemaker, RH | 1 |
| Stein, U | 1 |
10 other studies available for niclosamide and Invasiveness, Neoplasm
| Article | Year |
|---|---|
Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.
Topics: Cell Death; Cell Line, Tumor; Cell Movement; Extracellular Matrix Proteins; Gene Knockdown Technique | 2022 |
A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier.
Topics: Animals; Cell Communication; Cell Line, Tumor; Cell Proliferation; Colforsin; Drug Screening Assays, | 2021 |
Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Humans; | 2017 |
Niclosamide, an oral antihelmintic drug, exhibits antimetastatic activity in hepatocellular carcinoma cells through downregulating twist-mediated CD10 expression.
Topics: Administration, Oral; Anthelmintics; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dow | 2018 |
Interaction between epidermal growth factor receptor and interleukin-6 receptor in NSCLC progression.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Disease Progression; ErbB | 2019 |
The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model.
Topics: Animals; Anthelmintics; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell M | 2014 |
Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer.
Topics: Animals; Anticestodal Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Ce | 2016 |
S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Non-Small-Cell | 2016 |
Niclosamide: an established antihelminthic drug as a potential therapy against S100A4-mediated metastatic colon tumors.
Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce | 2011 |
Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.
Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce | 2011 |