Page last updated: 2024-11-01

niclosamide and Invasiveness, Neoplasm

niclosamide has been researched along with Invasiveness, Neoplasm in 10 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Research Excerpts

ExcerptRelevanceReference
"Osteosarcoma is a highly common malignant bone tumor."5.72Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022)
"The potency of niclosamide on breast cancer was assessed in vitro and in vivo."5.40The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014)
"Osteosarcoma is a highly common malignant bone tumor."1.72Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022)
"The morbidity of thyroid cancer has been rising obviously throughout the world during the past years."1.46Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro. ( An, Z; Li, S; Li, Y; Wang, C; Wang, T; Wang, X; Xie, Y; Ye, T; Yu, K; Zhang, M, 2017)
"The potency of niclosamide on breast cancer was assessed in vitro and in vivo."1.40The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014)
"Metastasis formation in colon cancer severely reduces the survival rate in patients."1.37Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. ( Fichtner, I; Kobelt, D; Lemm, M; Sack, U; Schlag, PM; Scudiero, D; Selby, M; Shoemaker, RH; Stein, U; Walther, W, 2011)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's8 (80.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Yeh, LT1
Lin, CW1
Lu, KH1
Hsieh, YH1
Yeh, CB2
Yang, SF2
Yang, JS1
Hilfenhaus, G1
MompeĆ³n, A1
Freshman, J1
Prajapati, DP1
Hernandez, G1
Freitas, VM1
Ma, F1
Langenbacher, AD1
Mirkov, S1
Song, D1
Cho, BK1
Goo, YA1
Pellegrini, M1
Chen, JN1
Damoiseaux, R1
Iruela-Arispe, ML1
Yu, K1
Wang, T1
Li, Y1
Wang, C2
Wang, X1
Zhang, M1
Xie, Y1
Li, S1
An, Z1
Ye, T2
Chien, MH1
Ho, YC1
Yang, YC1
Lai, SY1
Chen, WS1
Chen, MJ1
Yuquan, B1
Hexiao, T1
Laiyi, W1
Gaofeng, P1
Xuefeng, Z1
Ming, X1
Yanhong, W1
Li, Z1
Jinping, Z1
Xiong, Y1
Yan, Y1
Xia, Y1
Song, X1
Liu, L2
Li, D1
Wang, N1
Zhang, L1
Zhu, Y1
Zeng, J1
Wei, Y1
Yu, L1
Liu, J1
Chen, X1
Ward, T1
Pegram, M1
Shen, K1
Stewart, RL1
Carpenter, BL1
West, DS1
Knifley, T1
Weiss, HL1
Gal, TS1
Durbin, EB1
Arnold, SM1
O'Connor, KL1
Chen, M1
Helfman, DM1
Sack, U1
Walther, W1
Scudiero, D1
Selby, M1
Kobelt, D1
Lemm, M1
Fichtner, I1
Schlag, PM1
Shoemaker, RH1
Stein, U1

Other Studies

10 other studies available for niclosamide and Invasiveness, Neoplasm

ArticleYear
Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.
    International journal of molecular sciences, 2022, Jan-01, Volume: 23, Issue:1

    Topics: Cell Death; Cell Line, Tumor; Cell Movement; Extracellular Matrix Proteins; Gene Knockdown Technique

2022
A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier.
    Cancer research, 2021, 02-01, Volume: 81, Issue:3

    Topics: Animals; Cell Communication; Cell Line, Tumor; Cell Proliferation; Colforsin; Drug Screening Assays,

2021
Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Humans;

2017
Niclosamide, an oral antihelmintic drug, exhibits antimetastatic activity in hepatocellular carcinoma cells through downregulating twist-mediated CD10 expression.
    Environmental toxicology, 2018, Volume: 33, Issue:6

    Topics: Administration, Oral; Anthelmintics; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dow

2018
Interaction between epidermal growth factor receptor and interleukin-6 receptor in NSCLC progression.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:1

    Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Disease Progression; ErbB

2019
The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model.
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Animals; Anthelmintics; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell M

2014
Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:7

    Topics: Animals; Anticestodal Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Ce

2016
S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Non-Small-Cell

2016
Niclosamide: an established antihelminthic drug as a potential therapy against S100A4-mediated metastatic colon tumors.
    Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13

    Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce

2011
Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.
    Journal of the National Cancer Institute, 2011, Jul-06, Volume: 103, Issue:13

    Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce

2011