niclosamide has been researched along with Invasiveness, Neoplasm in 10 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Excerpt | Relevance | Reference |
---|---|---|
"Osteosarcoma is a highly common malignant bone tumor." | 5.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
"The potency of niclosamide on breast cancer was assessed in vitro and in vivo." | 5.40 | The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014) |
"Osteosarcoma is a highly common malignant bone tumor." | 1.72 | Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway. ( Hsieh, YH; Lin, CW; Lu, KH; Yang, JS; Yang, SF; Yeh, CB; Yeh, LT, 2022) |
"The morbidity of thyroid cancer has been rising obviously throughout the world during the past years." | 1.46 | Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro. ( An, Z; Li, S; Li, Y; Wang, C; Wang, T; Wang, X; Xie, Y; Ye, T; Yu, K; Zhang, M, 2017) |
"The potency of niclosamide on breast cancer was assessed in vitro and in vivo." | 1.40 | The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model. ( Li, D; Liu, L; Song, X; Wang, N; Wei, Y; Xia, Y; Xiong, Y; Yan, Y; Ye, T; Yu, L; Zeng, J; Zhang, L; Zhu, Y, 2014) |
"Metastasis formation in colon cancer severely reduces the survival rate in patients." | 1.37 | Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer. ( Fichtner, I; Kobelt, D; Lemm, M; Sack, U; Schlag, PM; Scudiero, D; Selby, M; Shoemaker, RH; Stein, U; Walther, W, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 8 (80.00) | 24.3611 |
2020's | 2 (20.00) | 2.80 |
Authors | Studies |
---|---|
Yeh, LT | 1 |
Lin, CW | 1 |
Lu, KH | 1 |
Hsieh, YH | 1 |
Yeh, CB | 2 |
Yang, SF | 2 |
Yang, JS | 1 |
Hilfenhaus, G | 1 |
MompeĆ³n, A | 1 |
Freshman, J | 1 |
Prajapati, DP | 1 |
Hernandez, G | 1 |
Freitas, VM | 1 |
Ma, F | 1 |
Langenbacher, AD | 1 |
Mirkov, S | 1 |
Song, D | 1 |
Cho, BK | 1 |
Goo, YA | 1 |
Pellegrini, M | 1 |
Chen, JN | 1 |
Damoiseaux, R | 1 |
Iruela-Arispe, ML | 1 |
Yu, K | 1 |
Wang, T | 1 |
Li, Y | 1 |
Wang, C | 2 |
Wang, X | 1 |
Zhang, M | 1 |
Xie, Y | 1 |
Li, S | 1 |
An, Z | 1 |
Ye, T | 2 |
Chien, MH | 1 |
Ho, YC | 1 |
Yang, YC | 1 |
Lai, SY | 1 |
Chen, WS | 1 |
Chen, MJ | 1 |
Yuquan, B | 1 |
Hexiao, T | 1 |
Laiyi, W | 1 |
Gaofeng, P | 1 |
Xuefeng, Z | 1 |
Ming, X | 1 |
Yanhong, W | 1 |
Li, Z | 1 |
Jinping, Z | 1 |
Xiong, Y | 1 |
Yan, Y | 1 |
Xia, Y | 1 |
Song, X | 1 |
Liu, L | 2 |
Li, D | 1 |
Wang, N | 1 |
Zhang, L | 1 |
Zhu, Y | 1 |
Zeng, J | 1 |
Wei, Y | 1 |
Yu, L | 1 |
Liu, J | 1 |
Chen, X | 1 |
Ward, T | 1 |
Pegram, M | 1 |
Shen, K | 1 |
Stewart, RL | 1 |
Carpenter, BL | 1 |
West, DS | 1 |
Knifley, T | 1 |
Weiss, HL | 1 |
Gal, TS | 1 |
Durbin, EB | 1 |
Arnold, SM | 1 |
O'Connor, KL | 1 |
Chen, M | 1 |
Helfman, DM | 1 |
Sack, U | 1 |
Walther, W | 1 |
Scudiero, D | 1 |
Selby, M | 1 |
Kobelt, D | 1 |
Lemm, M | 1 |
Fichtner, I | 1 |
Schlag, PM | 1 |
Shoemaker, RH | 1 |
Stein, U | 1 |
10 other studies available for niclosamide and Invasiveness, Neoplasm
Article | Year |
---|---|
Niclosamide Suppresses Migration and Invasion of Human Osteosarcoma Cells by Repressing TGFBI Expression via the ERK Signaling Pathway.
Topics: Cell Death; Cell Line, Tumor; Cell Movement; Extracellular Matrix Proteins; Gene Knockdown Technique | 2022 |
A High-Content Screen Identifies Drugs That Restrict Tumor Cell Extravasation across the Endothelial Barrier.
Topics: Animals; Cell Communication; Cell Line, Tumor; Cell Proliferation; Colforsin; Drug Screening Assays, | 2021 |
Niclosamide induces apoptosis through mitochondrial intrinsic pathway and inhibits migration and invasion in human thyroid cancer in vitro.
Topics: Apoptosis; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Humans; | 2017 |
Niclosamide, an oral antihelmintic drug, exhibits antimetastatic activity in hepatocellular carcinoma cells through downregulating twist-mediated CD10 expression.
Topics: Administration, Oral; Anthelmintics; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Movement; Dow | 2018 |
Interaction between epidermal growth factor receptor and interleukin-6 receptor in NSCLC progression.
Topics: A549 Cells; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Disease Progression; ErbB | 2019 |
The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model.
Topics: Animals; Anthelmintics; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell M | 2014 |
Combined niclosamide with cisplatin inhibits epithelial-mesenchymal transition and tumor growth in cisplatin-resistant triple-negative breast cancer.
Topics: Animals; Anticestodal Agents; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Ce | 2016 |
S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Non-Small-Cell | 2016 |
Niclosamide: an established antihelminthic drug as a potential therapy against S100A4-mediated metastatic colon tumors.
Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce | 2011 |
Novel effect of antihelminthic Niclosamide on S100A4-mediated metastatic progression in colon cancer.
Topics: Animals; Anthelmintics; Antineoplastic Agents; beta Catenin; Biomarkers, Tumor; Cell Line, Tumor; Ce | 2011 |