Page last updated: 2024-11-01

niclosamide and Insulin Resistance

niclosamide has been researched along with Insulin Resistance in 3 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research Excerpts

ExcerptRelevanceReference
"Niclosamide piperazine salt may hold the promise to become an alternative to NEN as a drug lead for the treatment of obesity and T2D."7.91Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice. ( Alasadi, A; Guo, J; Huang, Q; Jin, S; Tao, H, 2019)
"To assess the anti-obesity effects of niclosamide on mice with induced obesity."7.85Niclosamide as an anti-obesity drug: an experimental study. ( Al-Gareeb, AI; Aljubory, KD; Alkuraishy, HM, 2017)
"Niclosamide piperazine salt may hold the promise to become an alternative to NEN as a drug lead for the treatment of obesity and T2D."3.91Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice. ( Alasadi, A; Guo, J; Huang, Q; Jin, S; Tao, H, 2019)
"To assess the anti-obesity effects of niclosamide on mice with induced obesity."3.85Niclosamide as an anti-obesity drug: an experimental study. ( Al-Gareeb, AI; Aljubory, KD; Alkuraishy, HM, 2017)
"Niclosamide is an anthelmintic drug approved by the US Food and Drug Administration that uncouples the mitochondria of parasitic worms."1.40Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice. ( Jin, S; Shulman, GI; Tao, H; Zeng, X; Zhang, Y, 2014)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Guo, J1
Tao, H2
Alasadi, A1
Huang, Q1
Jin, S2
Zhang, Y1
Zeng, X1
Shulman, GI1
Al-Gareeb, AI1
Aljubory, KD1
Alkuraishy, HM1

Other Studies

3 other studies available for niclosamide and Insulin Resistance

ArticleYear
Niclosamide piperazine prevents high-fat diet-induced obesity and diabetic symptoms in mice.
    Eating and weight disorders : EWD, 2019, Volume: 24, Issue:1

    Topics: Animals; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Insulin Resistance; Mice

2019
Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.
    Nature medicine, 2014, Volume: 20, Issue:11

    Topics: Administration, Oral; Animals; Blood Glucose; Cell Respiration; Diabetes Mellitus, Experimental; Die

2014
Niclosamide as an anti-obesity drug: an experimental study.
    Eating and weight disorders : EWD, 2017, Volume: 22, Issue:2

    Topics: Animals; Anti-Obesity Agents; Blood Glucose; Body Weight; Cholesterol; Diet, High-Fat; Eating; Insul

2017