niclosamide has been researched along with Glaucoma in 1 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
Glaucoma: An ocular disease, occurring in many forms, having as its primary characteristics an unstable or a sustained increase in the intraocular pressure which the eye cannot withstand without damage to its structure or impairment of its function. The consequences of the increased pressure may be manifested in a variety of symptoms, depending upon type and severity, such as excavation of the optic disk, hardness of the eyeball, corneal anesthesia, reduced visual acuity, seeing of colored halos around lights, disturbed dark adaptation, visual field defects, and headaches. (Dictionary of Visual Science, 4th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We explored the effects of niclosamide on TGF-β1-induced fibrosis in these cells and examined its underlying mechanism of action." | 8.31 | Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway. ( Guo, J; Li, W; Liu, X; Wang, J; Wu, X; Zhang, L, 2023) |
| " We explored the effects of niclosamide on TGF-β1-induced fibrosis in these cells and examined its underlying mechanism of action." | 4.31 | Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway. ( Guo, J; Li, W; Liu, X; Wang, J; Wu, X; Zhang, L, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 1 |
| Li, W | 1 |
| Liu, X | 1 |
| Guo, J | 1 |
| Wu, X | 1 |
| Wang, J | 1 |
1 other study available for niclosamide and Glaucoma
| Article | Year |
|---|---|
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Topics: Cell Proliferation; Cells, Cultured; Cicatrix; Fibroblasts; Fibrosis; Glaucoma; Humans; MAP Kinase S | 2023 |