niclosamide has been researched along with Congenital Zika Syndrome in 5 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, we screened a small library of niclosamide derivatives and identified a new analogue with improved pharmacokinetic properties." | 5.56 | JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both ( Butler, D; Chen, H; D'Brant, L; Fan, X; Hu, S; Koetzner, CA; Kramer, LD; Kuo, L; Lang, Y; Li, H; Li, Z; Rugenstein, N; Samrat, SK; Tharappel, AM; Trudeau, N; Xu, J; Zhang, J; Zhang, QY; Zhou, J, 2020) |
| " Here, we screened a small library of niclosamide derivatives and identified a new analogue with improved pharmacokinetic properties." | 1.56 | JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both ( Butler, D; Chen, H; D'Brant, L; Fan, X; Hu, S; Koetzner, CA; Kramer, LD; Kuo, L; Lang, Y; Li, H; Li, Z; Rugenstein, N; Samrat, SK; Tharappel, AM; Trudeau, N; Xu, J; Zhang, J; Zhang, QY; Zhou, J, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 2 |
| Nath, A | 1 |
| Yang, W | 1 |
| Liu, LB | 1 |
| Liu, FL | 1 |
| Wu, YH | 1 |
| Zhen, ZD | 1 |
| Fan, DY | 1 |
| Sheng, ZY | 1 |
| Song, ZR | 1 |
| Chang, JT | 1 |
| Zheng, YT | 1 |
| An, J | 1 |
| Wang, PG | 1 |
| Huang, Y | 1 |
| Li, Q | 1 |
| Kang, L | 1 |
| Li, B | 1 |
| Ye, H | 1 |
| Duan, X | 1 |
| Xie, H | 1 |
| Jiang, M | 1 |
| Li, S | 1 |
| Zhu, Y | 1 |
| Tan, Q | 1 |
| Chen, L | 1 |
| Li, Z | 1 |
| Xu, J | 1 |
| Lang, Y | 1 |
| Fan, X | 1 |
| Kuo, L | 1 |
| D'Brant, L | 1 |
| Hu, S | 1 |
| Samrat, SK | 1 |
| Trudeau, N | 1 |
| Tharappel, AM | 1 |
| Rugenstein, N | 1 |
| Koetzner, CA | 1 |
| Zhang, J | 1 |
| Chen, H | 1 |
| Kramer, LD | 1 |
| Butler, D | 1 |
| Zhang, QY | 1 |
| Zhou, J | 1 |
| Li, H | 1 |
| Xu, M | 1 |
| Lee, EM | 1 |
| Wen, Z | 1 |
| Cheng, Y | 1 |
| Huang, WK | 1 |
| Qian, X | 1 |
| Tcw, J | 1 |
| Kouznetsova, J | 1 |
| Ogden, SC | 1 |
| Hammack, C | 1 |
| Jacob, F | 1 |
| Nguyen, HN | 1 |
| Itkin, M | 1 |
| Hanna, C | 1 |
| Shinn, P | 1 |
| Allen, C | 1 |
| Michael, SG | 1 |
| Huang, W | 1 |
| Christian, KM | 1 |
| Goate, A | 1 |
| Brennand, KJ | 1 |
| Huang, R | 1 |
| Xia, M | 1 |
| Ming, GL | 1 |
| Zheng, W | 1 |
| Song, H | 1 |
| Tang, H | 1 |
5 other studies available for niclosamide and Congenital Zika Syndrome
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Single-cell RNA sequencing reveals the fragility of male spermatogenic cells to Zika virus-induced complement activation.
Topics: Animals; Complement Activation; Male; Mice; Niclosamide; Sequence Analysis, RNA; Zika Virus; Zika Vi | 2023 |
Mitophagy Activation Targeting PINK1 Is an Effective Treatment to Inhibit Zika Virus Replication.
Topics: Animals; Mice; Mitophagy; Niclosamide; Protein Kinases; Ubiquitin; Zika Virus; Zika Virus Infection | 2023 |
JMX0207, a Niclosamide Derivative with Improved Pharmacokinetics, Suppresses Zika Virus Infection Both
Topics: Animals; Flavivirus; Humans; Niclosamide; Viral Nonstructural Proteins; Zika Virus; Zika Virus Infec | 2020 |
Identification of small-molecule inhibitors of Zika virus infection and induced neural cell death via a drug repurposing screen.
Topics: Astrocytes; Brain; Caspase 3; Caspase Inhibitors; Cell Death; Cell Line; Drug Repositioning; Humans; | 2016 |