niclosamide has been researched along with Alloxan Diabetes in 5 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Early diabetic kidney disease (DKD) is characterized by renal hypertrophy and albuminuria." | 1.48 | Niclosamide ethanolamine improves kidney injury in db/db mice. ( Ge, N; Han, P; Li, S; Shao, M; Song, G; Sun, H; Wang, W; Yi, T; Yu, X; Zhan, H; Zhang, C, 2018) |
| "Niclosamide is an anthelmintic drug approved by the US Food and Drug Administration that uncouples the mitochondria of parasitic worms." | 1.40 | Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice. ( Jin, S; Shulman, GI; Tao, H; Zeng, X; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Manuel, AM | 1 |
| Walla, MD | 1 |
| Faccenda, A | 1 |
| Martin, SL | 1 |
| Tanis, RM | 1 |
| Piroli, GG | 1 |
| Adam, J | 1 |
| Kantor, B | 1 |
| Mutus, B | 1 |
| Townsend, DM | 1 |
| Frizzell, N | 1 |
| Han, P | 1 |
| Zhan, H | 1 |
| Shao, M | 1 |
| Wang, W | 1 |
| Song, G | 1 |
| Yu, X | 1 |
| Zhang, C | 1 |
| Ge, N | 1 |
| Yi, T | 1 |
| Li, S | 1 |
| Sun, H | 1 |
| Tao, H | 1 |
| Zhang, Y | 1 |
| Zeng, X | 1 |
| Shulman, GI | 1 |
| Jin, S | 1 |
| Osório, J | 1 |
| Crunkhorn, S | 1 |
5 other studies available for niclosamide and Alloxan Diabetes
| Article | Year |
|---|---|
Succination of Protein Disulfide Isomerase Links Mitochondrial Stress and Endoplasmic Reticulum Stress in the Adipocyte During Diabetes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Diabetes Mellitus, Experimental; Endoplasmic Reticulum; Endoplasm | 2017 |
Niclosamide ethanolamine improves kidney injury in db/db mice.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Ethanol | 2018 |
Niclosamide ethanolamine-induced mild mitochondrial uncoupling improves diabetic symptoms in mice.
Topics: Administration, Oral; Animals; Blood Glucose; Cell Respiration; Diabetes Mellitus, Experimental; Die | 2014 |
Diabetes: antihelminthic drug for T2DM therapy?
Topics: Animals; Diabetes Mellitus, Experimental; Humans; Male; Mitochondria; Niclosamide; Uncoupling Agents | 2014 |
Metabolic disease: Mitochondrial uncoupler reverses diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Humans; Male; Mitochondria; Niclosamide; Uncoupling Agents | 2014 |