Page last updated: 2024-11-01

niclosamide and Adenocarcinoma

niclosamide has been researched along with Adenocarcinoma in 4 studies

Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.

Adenocarcinoma: A malignant epithelial tumor with a glandular organization.

Research Excerpts

ExcerptRelevanceReference
"Niclosamide treatment is associated with an inhibitory effect on CRC development and reduced Wnt activity."5.43The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway. ( Bocuk, D; Klemm, F; Koenig, S; Krause, P; Monin, MB; Niebert, S; Pukrop, T; Stelling, R, 2016)
"Niclosamide is an established anti-helminthic drug, which has recently been shown to inhibit the growth of various cancer cells."1.56Evaluation of the Anti-Tumor Activity of Niclosamide Nanoliposomes Against Colon Carcinoma. ( Hatamipour, M; Jaafari, MR; Momtazi-Borojeni, AA; Ramezani, M; Sahebkar, A, 2020)
"Niclosamide is an FDA‑approved anthelmintic drug, and may elicit antineoplastic effects through direct STAT3 inhibition, which has been revealed in numerous human cancer cells."1.56Niclosamide inhibits the cell proliferation and enhances the responsiveness of esophageal cancer cells to chemotherapeutic agents. ( Chen, YK; Hsu, YJ; Lee, MC; Lin, BR, 2020)
"Niclosamide treatment is associated with an inhibitory effect on CRC development and reduced Wnt activity."1.43The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway. ( Bocuk, D; Klemm, F; Koenig, S; Krause, P; Monin, MB; Niebert, S; Pukrop, T; Stelling, R, 2016)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Hatamipour, M1
Jaafari, MR1
Momtazi-Borojeni, AA1
Ramezani, M1
Sahebkar, A1
Lee, MC1
Chen, YK1
Hsu, YJ1
Lin, BR1
Stewart, RL1
Carpenter, BL1
West, DS1
Knifley, T1
Liu, L1
Wang, C1
Weiss, HL1
Gal, TS1
Durbin, EB1
Arnold, SM1
O'Connor, KL1
Chen, M1
Monin, MB1
Krause, P1
Stelling, R1
Bocuk, D1
Niebert, S1
Klemm, F1
Pukrop, T1
Koenig, S1

Other Studies

4 other studies available for niclosamide and Adenocarcinoma

ArticleYear
Evaluation of the Anti-Tumor Activity of Niclosamide Nanoliposomes Against Colon Carcinoma.
    Current molecular pharmacology, 2020, Volume: 13, Issue:3

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Doxorubicin; Dr

2020
Niclosamide inhibits the cell proliferation and enhances the responsiveness of esophageal cancer cells to chemotherapeutic agents.
    Oncology reports, 2020, Volume: 43, Issue:2

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cisplatin;

2020
S100A4 drives non-small cell lung cancer invasion, associates with poor prognosis, and is effectively targeted by the FDA-approved anti-helminthic agent niclosamide.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Carcinoma, Non-Small-Cell

2016
The anthelmintic niclosamide inhibits colorectal cancer cell lines via modulation of the canonical and noncanonical Wnt signaling pathway.
    The Journal of surgical research, 2016, 06-01, Volume: 203, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; beta Catenin; Biomarkers; Biomarkers, Tumor; Blottin

2016