niclosamide has been researched along with Acute Myelogenous Leukemia in 2 studies
Niclosamide: An antihelmintic that is active against most tapeworms. (From Martindale, The Extra Pharmacopoeia, 30th ed, p48)
niclosamide : A secondary carboxamide resulting from the formal condensation of the carboxy group of 5-chlorosalicylic acid with the amino group of 2-chloro-4-nitroaniline. It is an oral anthelmintic drug approved for use against tapeworm infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Niclosamide was synergistic with the frontline chemotherapeutic agents cytarabine, etoposide, and daunorubicin." | 5.36 | Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. ( Chen, C; Ding, K; Du, X; Jin, Y; Li, J; Lu, Z; Pan, J; Sun, X; Wu, Y; Zhou, J, 2010) |
| "Niclosamide was synergistic with the frontline chemotherapeutic agents cytarabine, etoposide, and daunorubicin." | 1.36 | Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species. ( Chen, C; Ding, K; Du, X; Jin, Y; Li, J; Lu, Z; Pan, J; Sun, X; Wu, Y; Zhou, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chae, HD | 1 |
| Cox, N | 1 |
| Capolicchio, S | 1 |
| Lee, JW | 1 |
| Horikoshi, N | 1 |
| Kam, S | 1 |
| Ng, AA | 1 |
| Edwards, J | 1 |
| Butler, TL | 1 |
| Chan, J | 1 |
| Lee, Y | 1 |
| Potter, G | 1 |
| Capece, MC | 1 |
| Liu, CW | 1 |
| Wakatsuki, S | 1 |
| Smith, M | 1 |
| Sakamoto, KM | 1 |
| Jin, Y | 1 |
| Lu, Z | 1 |
| Ding, K | 1 |
| Li, J | 1 |
| Du, X | 1 |
| Chen, C | 1 |
| Sun, X | 1 |
| Wu, Y | 1 |
| Zhou, J | 1 |
| Pan, J | 1 |
2 other studies available for niclosamide and Acute Myelogenous Leukemia
| Article | Year |
|---|---|
SAR optimization studies on modified salicylamides as a potential treatment for acute myeloid leukemia through inhibition of the CREB pathway.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; CREB-Binding Protein; Dose-Response Rel | 2019 |
Antineoplastic mechanisms of niclosamide in acute myelogenous leukemia stem cells: inactivation of the NF-kappaB pathway and generation of reactive oxygen species.
Topics: Adult; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; DNA, Neoplasm | 2010 |