Page last updated: 2024-10-19

nickel and Kidney Neoplasms

nickel has been researched along with Kidney Neoplasms in 16 studies

Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.

Kidney Neoplasms: Tumors or cancers of the KIDNEY.

Research Excerpts

ExcerptRelevanceReference
"In rats, an intrarenal injection of nickel subsulfide (Ni3S2) regularly caused, within 2 months, an erythrocytosis and eventually a renal carcinoma in 40 per cent of the animals."7.65Renal carcinomas and erythrocytosis in rats following intrarenal injection of nickel subsulfide. ( Jasmin, G; Riopelle, JL, 1976)
"In rats, an intrarenal injection of nickel subsulfide (Ni3S2) regularly caused, within 2 months, an erythrocytosis and eventually a renal carcinoma in 40 per cent of the animals."3.65Renal carcinomas and erythrocytosis in rats following intrarenal injection of nickel subsulfide. ( Jasmin, G; Riopelle, JL, 1976)
"In this study, kidney cancer cells namely human embryonic kidney 293-containing SV40 large T-antigen (HEK293T) and 786-0 were incubated with various concentrations of nickel chloride for 24 h before analysing the expression of three histone H3K27 methylation-modifying enzymes and H3K27me3 using quantitative real-time polymerase chain reaction, Western blot and immunofluorescence analyses."1.43The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells. ( Cai, Z; Fa, P; Gao, G; Gui, Y; Guo, X; Zhang, Q; Zhang, Y, 2016)
"For cadmium, the lack of statistical significance of most results, potential confounding and the absence of clear dose-response relations suggest that an association with RCC is unlikely to be causal."1.37Occupational exposure to arsenic, cadmium, chromium, lead and nickel, and renal cell carcinoma: a case-control study from Central and Eastern Europe. ( Bencko, V; Boffetta, P; Brennan, P; Chow, WH; Ferro, G; Fontana, L; Foretova, L; Janout, V; Jinga, V; Karami, S; Kollarova, H; Matveev, V; Moore, LE; Rothman, N; Stewart, P; Szeszenia-Dabrowska, N; van Bemmel, D; Zaridze, D, 2011)
"Laryngeal cancer and kidney cancer, both previously associated with nickel, were not in excess in these high risk groups."1.28A study of mortality in workers engaged in the mining, smelting, and refining of nickel. II: Mortality from cancer of the respiratory tract and kidney. ( Julian, JA; Muir, DC; Roberts, RS; Shannon, HS, 1989)
"The analysis focuses on mortality from cancer of the nasal sinuses, larynx, lung, and kidney."1.27Cancer mortality associated with the high-temperature oxidation of nickel subsulfide. ( Julian, JA; Muir, DC; Roberts, RS; Shannon, HS, 1984)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's3 (18.75)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Zhang, H1
Xu, Z1
Zhang, J1
Wei, D1
Liu, K1
Hu, W1
Wang, J1
Guo, X2
Zhang, Y1
Zhang, Q1
Fa, P1
Gui, Y2
Gao, G1
Cai, Z2
Boffetta, P1
Fontana, L1
Stewart, P1
Zaridze, D1
Szeszenia-Dabrowska, N1
Janout, V1
Bencko, V1
Foretova, L1
Jinga, V1
Matveev, V1
Kollarova, H1
Ferro, G1
Chow, WH1
Rothman, N1
van Bemmel, D1
Karami, S1
Brennan, P1
Moore, LE1
Lu, J1
Wang, Y1
Duan, X1
Masuda, K1
Ono, M1
Okamoto, M1
Morikawa, W1
Otsubo, M1
Migita, T1
Tsuneyoshi, M1
Okuda, H1
Shuin, T1
Naito, S1
Kuwano, M1
Sunderman, FW1
McCully, KS1
Hopfer, SM1
Roberts, RS2
Julian, JA2
Muir, DC2
Shannon, HS2
Eker, P1
Sanner, T1
Kasprzak, KS2
Diwan, BA2
Rice, JM3
LangÄrd, S1
Weghorst, CM1
Dragnev, KH1
Buzard, GS1
Thorne, KL1
Vandeborne, GF1
Vincent, KA1
Al-Saleh, IA1
Al-Doush, I1
Jasmin, G2
Solymoss, B1
Riopelle, JL1
Higinbotham, KG1
Reed, CD1
Perantoni, AO1

Reviews

1 review available for nickel and Kidney Neoplasms

ArticleYear
Nickel-related cancer in welders.
    The Science of the total environment, 1994, Jun-06, Volume: 148, Issue:2-3

    Topics: Humans; Kidney Neoplasms; Lung Neoplasms; Male; Nickel; Occupational Diseases; Risk Factors; Stainle

1994

Other Studies

15 other studies available for nickel and Kidney Neoplasms

ArticleYear
Disordered serum essential element levels are associated with increased risk of kidney tumors.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:21

    Topics: Chromium; Cobalt; Copper; Female; Humans; Kidney Neoplasms; Male; Manganese; Nickel; Selenium; Trace

2022
The regulatory role of nickel on H3K27 demethylase JMJD3 in kidney cancer cells.
    Toxicology and industrial health, 2016, Volume: 32, Issue:7

    Topics: HEK293 Cells; Histones; Humans; Jumonji Domain-Containing Histone Demethylases; Kidney; Kidney Neopl

2016
Occupational exposure to arsenic, cadmium, chromium, lead and nickel, and renal cell carcinoma: a case-control study from Central and Eastern Europe.
    Occupational and environmental medicine, 2011, Volume: 68, Issue:10

    Topics: Adult; Aged; Arsenic; Cadmium; Carcinoma, Renal Cell; Case-Control Studies; Chromium; Europe, Easter

2011
Ascorbate antagonizes nickel ion to regulate JMJD1A expression in kidney cancer cells.
    Acta biochimica et biophysica Sinica, 2012, Volume: 44, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Blotting, Western; Cell Line, Tumor; Dose-Response Relationshi

2012
Downregulation of Cap43 gene by von Hippel-Lindau tumor suppressor protein in human renal cancer cells.
    International journal of cancer, 2003, Jul-20, Volume: 105, Issue:6

    Topics: Carcinoma, Renal Cell; Cell Cycle Proteins; Cell Hypoxia; Cell Line; Down-Regulation; Gene Expressio

2003
Association between erythrocytosis and renal cancers in rats following intrarenal injection of nickel compounds.
    Carcinogenesis, 1984, Volume: 5, Issue:11

    Topics: Animals; Erythropoietin; Hematocrit; Kidney Neoplasms; Male; Nickel; Polycythemia; Rats; Rats, Inbre

1984
Cancer mortality associated with the high-temperature oxidation of nickel subsulfide.
    IARC scientific publications, 1984, Issue:53

    Topics: Adult; Canada; Carcinogens, Environmental; Humans; Kidney Neoplasms; Male; Metallurgy; Neoplasms; Ni

1984
Assay for initiators and promoters of carcinogenesis based on attachment-independent survival of cells in aggregates.
    Cancer research, 1983, Volume: 43, Issue:1

    Topics: Animals; Carcinogens; Cell Line; Cell Survival; Cocarcinogenesis; Kidney Neoplasms; Methylnitrosoure

1983
Iron accelerates while magnesium inhibits nickel-induced carcinogenesis in the rat kidney.
    Toxicology, 1994, May-31, Volume: 90, Issue:1-2

    Topics: Animals; Body Weight; Carcinogens; Drug Interactions; Iron; Kidney Neoplasms; Liver Neoplasms; Lung

1994
Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat renal mesenchymal tumors.
    Cancer research, 1994, Jan-01, Volume: 54, Issue:1

    Topics: Animals; Base Sequence; Dimethylnitrosamine; DNA Primers; Genes, p53; Kidney Neoplasms; Male; Molecu

1994
Sequential multielement analysis of Cd, Cr, Ni, and Pb in human tissues by inductively coupled plasma spectrometry.
    Bulletin of environmental contamination and toxicology, 1996, Volume: 57, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain Chemistry; Brain Neoplasms; Cadmium; Calibration;

1996
The topical effects of nickel subsulfide on renal parenchyma.
    Advances in experimental medicine and biology, 1977, Volume: 91

    Topics: Animals; Bronchial Neoplasms; Female; Inclusion Bodies; Injections, Intramuscular; Injections, Intra

1977
Renal carcinomas and erythrocytosis in rats following intrarenal injection of nickel subsulfide.
    Laboratory investigation; a journal of technical methods and pathology, 1976, Volume: 35, Issue:1

    Topics: Animals; Carcinogens; Cell Differentiation; Cytoplasm; Disulfides; Female; Kidney; Kidney Neoplasms;

1976
GGT to GTT transversions in codon 12 of the K-ras oncogene in rat renal sarcomas induced with nickel subsulfide or nickel subsulfide/iron are consistent with oxidative damage to DNA.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Animals; Base Sequence; Codon; DNA; DNA Damage; Genes, ras; Iron; Kidney Neoplasms; Molecular Sequen

1992
A study of mortality in workers engaged in the mining, smelting, and refining of nickel. II: Mortality from cancer of the respiratory tract and kidney.
    Toxicology and industrial health, 1989, Volume: 5, Issue:6

    Topics: Canada; Cohort Studies; Humans; Kidney Neoplasms; Lung Neoplasms; Male; Mining; Nickel; Occupational

1989