nickel and Hypoxia
nickel has been researched along with Hypoxia in 21 studies
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Exposure of cells to carcinogenic compounds of nickel(II) and cobalt(II) causes activation of the HIF-1 transcription factor and up-regulates a battery of hypoxia-inducible genes." | 3.72 | Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress. ( Bruick, RK; Donald, SP; Kasprzak, KS; Phang, JM; Salnikow, K; Zhitkovich, A, 2004) |
| "High-altitude pulmonary edema was then assessed by gravimetric analysis of heart and lung tissue, a visual score of lung hemorrhage, and measurement of protein content in bronchoalveolar lavage fluid." | 1.32 | Inhibitors of hypoxic pulmonary vasoconstriction prevent high-altitude pulmonary edema in rats. ( Berg, JT; Ramanathan, S; Swenson, ER, 2004) |
Research
Studies (21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (23.81) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 12 (57.14) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Huang, X | 1 |
| Zhang, W | 1 |
| Peng, Y | 1 |
| Gao, L | 1 |
| Wang, F | 1 |
| Wang, L | 1 |
| Wei, X | 1 |
| Pasquali, M | 1 |
| Martini, P | 1 |
| Shahi, A | 1 |
| Jalilian, AR | 1 |
| Osso, JA | 1 |
| Boschi, A | 1 |
| Blaby-Haas, CE | 1 |
| Castruita, M | 1 |
| Fitz-Gibbon, ST | 1 |
| Kropat, J | 1 |
| Merchant, SS | 1 |
| Davidson, T | 2 |
| Salnikow, K | 3 |
| Costa, M | 2 |
| Berg, JT | 1 |
| Ramanathan, S | 1 |
| Swenson, ER | 1 |
| Li, X | 1 |
| Lippmann, M | 1 |
| Zhao, J | 1 |
| Chen, H | 1 |
| Kluz, T | 1 |
| Zhang, Q | 1 |
| Donald, SP | 1 |
| Bruick, RK | 1 |
| Zhitkovich, A | 1 |
| Phang, JM | 1 |
| Kasprzak, KS | 1 |
| Barac-Nieto, M | 1 |
| Constantinescu, A | 1 |
| Pina-Benabou, MH | 1 |
| Rozental, R | 1 |
| Higashide, S | 1 |
| Morikawa, K | 1 |
| Okumura, M | 1 |
| Kondo, S | 1 |
| Ogata, M | 1 |
| Murakami, T | 1 |
| Yamashita, A | 1 |
| Kanemoto, S | 1 |
| Manabe, T | 1 |
| Imaizumi, K | 1 |
| Campanucci, VA | 1 |
| Nurse, CA | 1 |
| Hepp, S | 1 |
| Gerich, FJ | 1 |
| Müller, M | 1 |
| Vengellur, A | 1 |
| Phillips, JM | 1 |
| Hogenesch, JB | 1 |
| LaPres, JJ | 1 |
| Rubanyi, G | 2 |
| Ligeti, L | 2 |
| Koller, A | 2 |
| Kovach, AG | 2 |
| Jing, J | 1 |
| Aitken, PG | 1 |
| Somjen, GG | 1 |
| Steinbrech, DS | 1 |
| Mehrara, BJ | 1 |
| Saadeh, PB | 1 |
| Greenwald, JA | 1 |
| Spector, JA | 1 |
| Gittes, GK | 1 |
| Longaker, MT | 1 |
| Fredrickson, JK | 1 |
| Zachara, JM | 1 |
| Kukkadapu, RK | 1 |
| Gorby, YA | 1 |
| Smith, SC | 1 |
| Brown, CF | 1 |
| Ballagi, G | 1 |
| Balogh, I | 1 |
| Kaplar, Z | 1 |
| Graf, Z | 1 |
| Smith, RJ | 1 |
| Ignarro, LJ | 1 |
| Heidger, PM | 1 |
| Fisher, JW | 1 |
| Ong, SD | 1 |
| Bailey, LE | 1 |
Reviews
2 reviews available for nickel and Hypoxia
| Article | Year |
|---|---|
Copper-64 based radiopharmaceuticals for brain tumors and hypoxia imaging.
Topics: Animals; Brain Neoplasms; Coordination Complexes; Copper Radioisotopes; Humans; Hypoxia; Isotopes; N | 2020 |
Nickel ions and ischemic coronary vasoconstriction.
Topics: Adenosine; Animals; Calcium; Coronary Disease; Hypoxia; Models, Biological; Nickel; Phenoxybenzamine | 1984 |
Other Studies
19 other studies available for nickel and Hypoxia
| Article | Year |
|---|---|
A Multifunctional Layered Nickel Silicate Nanogenerator of Synchronous Oxygen Self-supply and Superoxide Radical Generation for Hypoxic Tumor Therapy.
Topics: Cell Line, Tumor; Humans; Hypoxia; Nanoparticles; Nickel; Oxygen; Photochemotherapy; Photosensitizin | 2022 |
Ni induces the CRR1-dependent regulon revealing overlap and distinction between hypoxia and Cu deficiency responses in Chlamydomonas reinhardtii.
Topics: Chlamydomonas reinhardtii; Copper; Gene Expression Regulation, Plant; Homeostasis; Hypoxia; Nickel; | 2016 |
Hypoxia inducible factor-1 alpha-independent suppression of aryl hydrocarbon receptor-regulated genes by nickel.
Topics: Animals; Down-Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Inbred C57 | 2003 |
Inhibitors of hypoxic pulmonary vasoconstriction prevent high-altitude pulmonary edema in rats.
Topics: Acetazolamide; Altitude; Animals; Bronchoalveolar Lavage; Hypoxia; Male; Nickel; Pulmonary Edema; Ra | 2004 |
Effect of nickel and iron co-exposure on human lung cells.
Topics: Air Pollutants; Blotting, Western; Carbon; Cell Cycle Proteins; Chlorides; Coal Ash; Deferoxamine; E | 2004 |
Nickel-induced 1,4-alpha-glucan branching enzyme 1 up-regulation via the hypoxic signaling pathway.
Topics: 1,4-alpha-Glucan Branching Enzyme; Animals; Cells, Cultured; Gene Expression Regulation, Enzymologic | 2004 |
Depletion of intracellular ascorbate by the carcinogenic metals nickel and cobalt results in the induction of hypoxic stress.
Topics: Ascorbic Acid; Blotting, Western; Carcinogens; Cell Line; Chromatography, High Pressure Liquid; Coba | 2004 |
Hypoxic rise in cytosolic calcium and renal proximal tubule injury mediated by a nickel-sensitive pathway.
Topics: Animals; Calcium; Calcium Channel Blockers; Cytoplasm; Female; GABA Modulators; Humans; Hypoxia; Kid | 2004 |
Identification of regulatory cis-acting elements for alternative splicing of presenilin 2 exon 5 under hypoxic stress conditions.
Topics: Alternative Splicing; Alzheimer Disease; Brain; Cell Line, Tumor; Dose-Response Relationship, Drug; | 2004 |
Biophysical characterization of whole-cell currents in O2-sensitive neurons from the rat glossopharyngeal nerve.
Topics: 4-Aminopyridine; Action Potentials; Animals; Animals, Newborn; Cadmium; Calcium Channels; Cells, Cul | 2005 |
Sulfhydryl oxidation reduces hippocampal susceptibility to hypoxia-induced spreading depression by activating BK channels.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aniline Compounds; Animals; Calcium; Charybdotoxin; Cortical S | 2005 |
Gene expression profiling of hypoxia signaling in human hepatocellular carcinoma cells.
Topics: Algorithms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cobalt; Deferoxamine; DNA Primers; Down-Reg | 2005 |
Possible role of nickel ions in the pathogenesis of ischemic coronary vasoconstriction in the dog heart.
Topics: Adenosine; Animals; Coronary Circulation; Coronary Disease; Dogs; Dose-Response Relationship, Drug; | 1984 |
Role of calcium channels in spreading depression in rat hippocampal slices.
Topics: Animals; Calcium; Calcium Channels; Cortical Spreading Depression; Electrophysiology; Hippocampus; H | 1993 |
VEGF expression in an osteoblast-like cell line is regulated by a hypoxia response mechanism.
Topics: Animals; Cell Line; Cobalt; Cycloheximide; Dactinomycin; Dexamethasone; Dose-Response Relationship, | 2000 |
Biotransformation of Ni-substituted hydrous ferric oxide by an Fe(III)-reducing bacterium.
Topics: Biotransformation; Ferric Compounds; Humic Substances; Hypoxia; Nickel; Shewanella putrefaciens; Wat | 2001 |
Nickel and vanadium analysis and cytochemistry of heart muscle and sera under different pathological conditions.
Topics: Animals; Carbon Monoxide Poisoning; Electron Probe Microanalysis; Female; Histocytochemistry; Humans | 1986 |
Lysosomal enzyme release in vivo: an evaluation of the mechanism of cobalt polycythemia.
Topics: Acid Phosphatase; Animals; Cobalt; Erythropoiesis; Erythropoietin; Female; Glucuronidase; Histocytoc | 1974 |
Uncoupling of excitation from contraction by nickel in cardiac muscle.
Topics: Animals; Calcium; Cats; Electrophysiology; Female; Heart; Hypoxia; In Vitro Techniques; Kinetics; Ma | 1973 |