nickel has been researched along with Histiocytoma, Benign Fibrous in 6 studies
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.
Histiocytoma, Benign Fibrous: A benign tumor composed, wholly or in part, of cells with the morphologic characteristics of HISTIOCYTES and with various fibroblastic components. Fibrous histiocytomas can occur anywhere in the body. When they occur in the skin, they are called dermatofibromas or sclerosing hemangiomas. (From DeVita Jr et al., Cancer: Principles & Practice of Oncology, 5th ed, p1747)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Malignant fibrous histiocytomas arose in all mice, and we have characterized the profile of tumor suppressor genes and signal transduction pathways altered in these cells." | 1.31 | Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase. ( Arbiser, JL; Bai, X; Govindarajan, B; Klafter, R; LaMontagne, K; Mansur, C; Miller, MS; Mizesko, M, 2002) |
| " Nickel alloy showed high carcinogenic and toxic potencies, whereas other materials showed no evidence of them." | 1.29 | Evaluation of carcinogenicity and chronic toxicity associated with orthopedic implants in mice. ( Hayashi, K; Ishinishi, N; Sugioka, Y; Takamura, K; Yamada, T, 1994) |
| "Out of 8 malignant fibrous histiocytomas, cathepsin B was detectable in all, but the other antigens were absent." | 1.27 | Histopathological and immunohistochemical studies on nickel sulfide-induced tumors in F344 rats. ( Izumi, K; Otsuka, H; Sano, N; Shibata, M, 1988) |
| "Malignant testicular neoplasms developed in 16 of 19 rats within 20 months after an injection of 10 mg of Ni3S2." | 1.26 | Induction of testicular sarcomas in Fischer rats by intratesticular injection of nickel subsulfide. ( Allpass, PR; Damjanov, I; Mitchell, JM; Sunderman, FW, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Takamura, K | 1 |
| Hayashi, K | 1 |
| Ishinishi, N | 1 |
| Yamada, T | 1 |
| Sugioka, Y | 1 |
| Govindarajan, B | 1 |
| Klafter, R | 1 |
| Miller, MS | 1 |
| Mansur, C | 1 |
| Mizesko, M | 1 |
| Bai, X | 1 |
| LaMontagne, K | 1 |
| Arbiser, JL | 1 |
| Damjanov, I | 1 |
| Sunderman, FW | 1 |
| Mitchell, JM | 1 |
| Allpass, PR | 1 |
| Shibata, M | 2 |
| Izumi, K | 2 |
| Sano, N | 2 |
| Akagi, A | 1 |
| Otsuka, H | 2 |
| Hebert, GJ | 1 |
| Basrur, PK | 1 |
| Gilman, JP | 1 |
6 other studies available for nickel and Histiocytoma, Benign Fibrous
| Article | Year |
|---|---|
Evaluation of carcinogenicity and chronic toxicity associated with orthopedic implants in mice.
Topics: Alloys; Aluminum Oxide; Animals; Biocompatible Materials; Carcinogenicity Tests; Female; Fibrosarcom | 1994 |
Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase.
Topics: Animals; Carcinogens; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; DNA Methylation; Drug Impl | 2002 |
Induction of testicular sarcomas in Fischer rats by intratesticular injection of nickel subsulfide.
Topics: Animals; Atrophy; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Fibrosarcoma; H | 1978 |
Induction of soft tissue tumours in F344 rats by subcutaneous, intramuscular, intra-articular, and retroperitoneal injection of nickel sulphide (Ni3S2).
Topics: Animals; Fibrosarcoma; Histiocytoma, Benign Fibrous; Injections, Intra-Articular; Injections, Intram | 1989 |
Histopathological and immunohistochemical studies on nickel sulfide-induced tumors in F344 rats.
Topics: Animals; Cathepsin B; Desmin; Histiocytoma, Benign Fibrous; Immunohistochemistry; Male; Myoglobin; M | 1988 |
Arginase activity in nickel sulfide-induced rat tumors.
Topics: Animals; Arginase; Carcinogens; Histiocytoma, Benign Fibrous; Lung; Lymphoma, Large B-Cell, Diffuse; | 1970 |