nickel has been researched along with Hepatolenticular Degeneration in 6 studies
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Neuromedin C is a bombesin-like neuropeptide of the sequence Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2." | 1.29 | Neuromedin C binds Cu(II) and Ni(II) via the ATCUN motif: implications for the CNS and cancer growth. ( Harford, C; Sarkar, B, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (66.67) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SUNDERMAN, FW | 3 |
| WHITE, JC | 1 |
| Harford, C | 1 |
| Sarkar, B | 2 |
| DiDonato, M | 1 |
| Narindrasorasak, S | 1 |
| Forbes, JR | 1 |
| Cox, DW | 1 |
| Reinhold, JG | 1 |
| Roth, LE | 1 |
| Shigenaka, Y | 1 |
2 reviews available for nickel and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Trace elements--a selective survey.
Topics: Adult; Child; Chromium; Cobalt; Copper; Erythrocytes; Fluorine; Hepatolenticular Degeneration; Human | 1975 |
Atomic absorption spectrometry of trace metals in clinical pathology.
Topics: Brain Diseases; Chromium; Copper; Deficiency Diseases; Growth Disorders; Hair; Hepatolenticular Dege | 1973 |
4 other studies available for nickel and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Metabolic balance studies in hepatolenticular degeneration treated with diethyldithiocarbamate.
Topics: Carbamates; Chelating Agents; Copper; Ditiocarb; Hepatolenticular Degeneration; Humans; Minerals; Ni | 1963 |
Neuromedin C binds Cu(II) and Ni(II) via the ATCUN motif: implications for the CNS and cancer growth.
Topics: Amino Acid Sequence; Animals; Binding Sites; Bombesin; Central Nervous System; Circular Dichroism; C | 1995 |
Expression, purification, and metal binding properties of the N-terminal domain from the wilson disease putative copper-transporting ATPase (ATP7B).
Topics: Adenosine Triphosphatases; Binding, Competitive; Carrier Proteins; Cation Transport Proteins; Cobalt | 1997 |
Microtubules in the heliozoan axopodium. II. Rapid degradation by cupric and nickelous ions.
Topics: Cell Division; Cell Membrane; Copper; Cytoplasm; Eukaryota; Flagella; Hepatolenticular Degeneration; | 1970 |