nickel has been researched along with Experimental Lung Inflammation in 26 studies
Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.
Experimental Lung Inflammation: Inflammation of any part, segment or lobe, of the lung parenchyma.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of isoflurane." | 7.83 | Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats. ( Ajimi, S; Hashizume, N; Imatanaka, N; Kobayashi, T; Nakai, M; Oshima, Y; Tsubokura, Y, 2016) |
| " Two common means of anesthesia before euthanasia and bronchoalveolar lavage in rats are intraperitoneal injection of pentobarbital and inhalation of isoflurane." | 3.83 | Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats. ( Ajimi, S; Hashizume, N; Imatanaka, N; Kobayashi, T; Nakai, M; Oshima, Y; Tsubokura, Y, 2016) |
| "At first, dose-response and time-response studies were performed to observe lung inflammation and injury caused by Nano-Ni." | 1.51 | Comparative mouse lung injury by nickel nanoparticles with differential surface modification. ( Jiang, M; Li, H; Li, J; Mo, Y; Tang, S; Wan, R; Zhang, Q; Zhang, Y; Zhong, CJ, 2019) |
| "Although there are several reports on lung injury caused by indium-containing compounds, the toxicity of nanoscale indium oxide (In2O3) particles has not been reported." | 1.43 | Indium oxide (In2O3) nanoparticles induce progressive lung injury distinct from lung injuries by copper oxide (CuO) and nickel oxide (NiO) nanoparticles. ( Cho, WS; Jeong, J; Kim, J; Seok, SH, 2016) |
| "Taken together, a difference in pulmonary inflammation was observed between the high and low toxicity nanomaterials in the intratracheal instillation studies, as in the inhalation studies, suggesting that intratracheal instillation studies may be useful for ranking the harmful effects of nanoparticles." | 1.43 | Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles. ( Horie, M; Izumi, H; Kawaguchi, K; Kawai, K; Kitajima, S; Kubo, M; Kuroda, E; Lee, BW; Morimoto, Y; Myojo, T; Okada, T; Oyabu, T; Sasaki, T; Shimada, M; Tomonaga, T; Yamamoto, K; Yatera, K; Yoshiura, Y, 2016) |
| "NiONP exposure resulted in sustained pulmonary inflammation accompanied by inflammatory cell infiltration, alveolar proteinosis, and cytokine secretion." | 1.43 | Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats. ( Cao, Z; Fang, Y; He, M; Lu, Y; Ma, Q; Pi, H; Qian, F; Yu, Z; Zhou, Z, 2016) |
| " Inhalation exposure to both HMTAs likely causes lung injury by inducing macrophage activation, neutrophilia, and the generation of toxic oxygen radicals." | 1.38 | Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles. ( Cafasso, DE; Lee, KW; Pierce, LM; Roedel, EQ, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 1 (3.85) | 18.2507 |
| 2000's | 2 (7.69) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| You, DJ | 1 |
| Lee, HY | 1 |
| Taylor-Just, AJ | 1 |
| Linder, KE | 1 |
| Bonner, JC | 1 |
| Mo, Y | 2 |
| Zhang, Y | 2 |
| Wan, R | 2 |
| Jiang, M | 2 |
| Xu, Y | 1 |
| Zhang, Q | 3 |
| Bai, KJ | 1 |
| Chuang, KJ | 1 |
| Chen, JK | 1 |
| Hua, HE | 1 |
| Shen, YL | 1 |
| Liao, WN | 1 |
| Lee, CH | 1 |
| Chen, KY | 1 |
| Lee, KY | 1 |
| Hsiao, TC | 1 |
| Pan, CH | 1 |
| Ho, KF | 1 |
| Chuang, HC | 1 |
| Yang, L | 1 |
| Lin, Z | 1 |
| Wang, Y | 1 |
| Li, C | 1 |
| Xu, W | 1 |
| Li, Q | 1 |
| Yao, W | 1 |
| Song, Z | 1 |
| Liu, G | 1 |
| Li, J | 1 |
| Zhong, CJ | 1 |
| Li, H | 1 |
| Tang, S | 1 |
| Jeong, J | 1 |
| Kim, J | 1 |
| Seok, SH | 1 |
| Cho, WS | 2 |
| Morimoto, Y | 4 |
| Izumi, H | 1 |
| Yoshiura, Y | 1 |
| Tomonaga, T | 1 |
| Lee, BW | 3 |
| Okada, T | 1 |
| Oyabu, T | 4 |
| Myojo, T | 4 |
| Kawai, K | 1 |
| Yatera, K | 1 |
| Shimada, M | 2 |
| Kubo, M | 1 |
| Yamamoto, K | 2 |
| Kitajima, S | 1 |
| Kuroda, E | 2 |
| Horie, M | 1 |
| Kawaguchi, K | 1 |
| Sasaki, T | 1 |
| Cao, Z | 1 |
| Fang, Y | 1 |
| Lu, Y | 1 |
| Qian, F | 1 |
| Ma, Q | 1 |
| He, M | 1 |
| Pi, H | 1 |
| Yu, Z | 1 |
| Zhou, Z | 1 |
| Tsubokura, Y | 1 |
| Kobayashi, T | 1 |
| Oshima, Y | 1 |
| Hashizume, N | 1 |
| Nakai, M | 1 |
| Ajimi, S | 1 |
| Imatanaka, N | 1 |
| Lu, S | 1 |
| Duffin, R | 2 |
| Poland, C | 1 |
| Daly, P | 1 |
| Murphy, F | 1 |
| Drost, E | 1 |
| Macnee, W | 2 |
| Stone, V | 1 |
| Donaldson, K | 3 |
| Poland, CA | 1 |
| Howie, SE | 1 |
| Bradley, M | 1 |
| Megson, IL | 1 |
| Ogami, A | 3 |
| Todoroki, M | 2 |
| Yamamoto, M | 2 |
| Murakami, M | 1 |
| Hirohashi, M | 2 |
| Nishi, K | 2 |
| Kadoya, C | 2 |
| Yamasaki, S | 1 |
| Nagatomo, H | 1 |
| Fujita, K | 1 |
| Endoh, S | 2 |
| Uchida, K | 2 |
| Kobayashi, N | 1 |
| Nakanishi, J | 2 |
| Tanaka, I | 3 |
| Hashiba, M | 2 |
| Mizuguchi, Y | 2 |
| Kambara, T | 1 |
| Roedel, EQ | 1 |
| Cafasso, DE | 1 |
| Lee, KW | 1 |
| Pierce, LM | 1 |
| Hamilton, RF | 1 |
| Buford, M | 1 |
| Xiang, C | 1 |
| Wu, N | 1 |
| Holian, A | 1 |
| SUNDERMAN, FW | 2 |
| RANGE, CL | 1 |
| DONNELLY, AJ | 1 |
| LUCYSZYN, GW | 1 |
| Kusaka, Y | 1 |
| Sato, K | 1 |
| Nakakuki, K | 1 |
| Kohyama, N | 1 |
| Hardie, WD | 1 |
| Prows, DR | 1 |
| Piljan-Gentle, A | 1 |
| Dunlavy, MR | 1 |
| Wesselkamper, SC | 1 |
| Leikauf, GD | 1 |
| Korfhagen, TR | 1 |
| Ottolenghi, AD | 1 |
| Haseman, JK | 1 |
| Payne, WW | 1 |
| Falk, HL | 1 |
| MacFarland, HN | 1 |
| Trubnikov, GV | 4 |
| Kasprzak, KS | 1 |
| Marchow, L | 1 |
| Breborowicz, J | 1 |
| Surikova, ZA | 1 |
| Fomin, AA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized, Double-Blinded, Placebo-Controlled Study With Immunotype Specific Dietary Supplements to Improve Inflammatory Age® by Edifice Health[NCT04983017] | 750 participants (Anticipated) | Interventional | 2021-08-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
26 other studies available for nickel and Experimental Lung Inflammation
| Article | Year |
|---|---|
Sex differences in the acute and subchronic lung inflammatory responses of mice to nickel nanoparticles.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; Female; Humans; Inhalation Exposure; Interle | 2020 |
miR-21 mediates nickel nanoparticle-induced pulmonary injury and fibrosis.
Topics: Animals; Cytokines; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Na | 2020 |
Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Bronchoalveolar Lavage Fluid; Deoxyguanosine; Female; Lung Inj | 2018 |
Nickle(II) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating the ROS/Akt signaling pathway.
Topics: A549 Cells; Animals; Bleomycin; Cell Survival; Disease Models, Animal; Humans; Mice; Mice, Inbred C5 | 2018 |
Comparative mouse lung injury by nickel nanoparticles with differential surface modification.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokine CXCL1; DNA Damage; L-Lactate Dehydrogenase; Lung In | 2019 |
Indium oxide (In2O3) nanoparticles induce progressive lung injury distinct from lung injuries by copper oxide (CuO) and nickel oxide (NiO) nanoparticles.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cells, Cultured; Copper; Cytokines; Female; Indium; Ki-67 Ant | 2016 |
Comparison of pulmonary inflammatory responses following intratracheal instillation and inhalation of nanoparticles.
Topics: Administration, Inhalation; Animals; Bronchoalveolar Lavage Fluid; Cytokines; Instillation, Drug; Lu | 2016 |
Exposure to nickel oxide nanoparticles induces pulmonary inflammation through NLRP3 inflammasome activation in rats.
Topics: Animals; Carrier Proteins; Caspase 1; Caspase Inhibitors; Cell Line; Cytokines; Environmental Pollut | 2016 |
Effects of pentobarbital, isoflurane, or medetomidine-midazolam-butorphanol anesthesia on bronchoalveolar lavage fluid and blood chemistry in rats.
Topics: Administration, Inhalation; Analgesics, Opioid; Anesthesia; Anesthetics, Inhalation; Animals; Biomar | 2016 |
Efficacy of simple short-term in vitro assays for predicting the potential of metal oxide nanoparticles to cause pulmonary inflammation.
Topics: Aluminum Oxide; Cell Line; Erythrocytes; Hemolysis; Humans; Metal Nanoparticles; Nickel; Oxides; Pne | 2009 |
Metal oxide nanoparticles induce unique inflammatory footprints in the lung: important implications for nanoparticle testing.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cerium; Copper; Cytokines; Female; Hazardous Substances; Inha | 2010 |
Expression of inflammation-related cytokines following intratracheal instillation of nickel oxide nanoparticles.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Instillation, Drug; Intuba | 2010 |
Pulmonary toxicity following an intratracheal instillation of nickel oxide nanoparticle agglomerates.
Topics: Animals; Bronchoalveolar Lavage Fluid; Chemokines; Chemokines, CXC; Leukocyte Count; Male; Metal Nan | 2011 |
Pulmonary toxicity after exposure to military-relevant heavy metal tungsten alloy particles.
Topics: Alloys; Animals; Bronchoalveolar Lavage Fluid; Cell Survival; Cells, Cultured; Cobalt; Cytokines; DN | 2012 |
NLRP3 inflammasome activation in murine alveolar macrophages and related lung pathology is associated with MWCNT nickel contamination.
Topics: Animals; Carrier Proteins; Caspase 1; Caspase Inhibitors; Cathepsin B; Cells, Cultured; Cytokines; I | 2012 |
Comparison of dose-response relations between 4-week inhalation and intratracheal instillation of NiO nanoparticles using polimorphonuclear neutrophils in bronchoalveolar lavage fluid as a biomarker of pulmonary inflammation.
Topics: Animals; Bronchoalveolar Lavage Fluid; Dose-Response Relationship, Drug; Inhalation Exposure; Instil | 2013 |
Nickel poisoning. XII. Metabolic and pathologic changes in acute pneumonitis from nickel carbonyl.
Topics: Heavy Metal Poisoning; Humans; Lung Abscess; Metals, Heavy; Nickel; Organometallic Compounds; Pneumo | 1961 |
Differences in the extent of inflammation caused by intratracheal exposure to three ultrafine metals: role of free radicals.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cobalt; Free Radicals; L-Lactate Dehydrogenase; Lipid Peroxid | 1998 |
Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha.
Topics: Animals; Bronchoalveolar Lavage Fluid; Cytokines; Dose-Response Relationship, Drug; Humans; Lung; Mi | 2002 |
Inhalation studies of nickel sulfide in pulmonary carcinogenesis of rats.
Topics: Animals; Body Weight; Butanes; Carcinogens; Environmental Exposure; Female; Germ-Free Life; Humans; | 1975 |
[Content of elements (iron, copper, manganese, nickel, aluminium, chromium, and strontium) in plasma and blood erythrocytes in lung and liver tissue in patients with acute pneumonias].
Topics: Acute Disease; Adolescent; Adult; Aluminum; Chromium; Copper; Female; Humans; Iron; Liver; Lung; Mal | 1976 |
[Level of microelements in the sputum of patients with inflammatory and tumorous processes of the lungs].
Topics: Adult; Aged; Aluminum; Bronchiectasis; Carcinoma, Bronchogenic; Chromium; Chronic Disease; Copper; E | 1975 |
Pathological reactions in rat lungs following intratracheal injection of nickel subsulfide and 3,4-benzpyrene.
Topics: Adenoma; Animals; Benzopyrenes; Bronchial Diseases; Carcinogens; Drug Synergism; Inflammation; Injec | 1973 |
[Nickel, aluminum and chromium levels in the blood plasms of patients with chronic pneumonia].
Topics: Adult; Aged; Aluminum; Chromium; Chronic Disease; Female; Humans; Male; Middle Aged; Nickel; Pneumon | 1969 |
[Nickel content in the blood of children with pneumonia].
Topics: Child, Preschool; Humans; Infant; Nickel; Pneumonia | 1967 |
[Blood plasma iron, copper, manganese, aluminum, nickel and chromium content in inflammatory diseases of the lungs and bronchial asthma].
Topics: Adult; Aluminum; Asthma; Chromium; Copper; Female; Humans; Iron; Male; Manganese; Middle Aged; Nicke | 1968 |