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nickel and Alveolitis, Fibrosing

nickel has been researched along with Alveolitis, Fibrosing in 23 studies

Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.

Research Excerpts

ExcerptRelevanceReference
"Nickel oxide nanoparticles (NiO NPs) causes pulmonary fibrosis via activating transforming growth factor-β1 (TGF-β1) in rats, but its upstream regulatory mechanisms are unknown."8.02LncRNA MEG3 mediates nickel oxide nanoparticles-induced pulmonary fibrosis via suppressing TGF-β1 expression and epithelial-mesenchymal transition process. ( Chang, X; Gao, Q; Li, C; Li, S; Liu, H; Sun, Y; Wang, X; Yang, M; Zhan, H, 2021)
"Animal studies have shown that nickel compounds may induce pulmonary fibrosis, but so far only limited documentation in humans has been available."7.72Radiographic evidence of pulmonary fibrosis and possible etiologic factors at a nickel refinery in Norway. ( Berge, SR; Skyberg, K, 2003)
"To identify pulmonary fibrosis, Masson trichrome staining, hydroxyproline content, and collagen protein expression were performed."5.46Nickel oxide nanoparticles induced pulmonary fibrosis via TGF- β1 activation in rats. ( Chang, XH; Han, AJ; Li, J; Li, S; Liu, FF; Liu, SK; Su, L; Sun, YB; Sun, YF; Sun, YY; Zhou, HH; Zhu, A; Zou, LY, 2017)
"Nickel oxide nanoparticles (NiO NPs) causes pulmonary fibrosis via activating transforming growth factor-β1 (TGF-β1) in rats, but its upstream regulatory mechanisms are unknown."4.02LncRNA MEG3 mediates nickel oxide nanoparticles-induced pulmonary fibrosis via suppressing TGF-β1 expression and epithelial-mesenchymal transition process. ( Chang, X; Gao, Q; Li, C; Li, S; Liu, H; Sun, Y; Wang, X; Yang, M; Zhan, H, 2021)
"Nickel oxide nanoparticles (Nano NiO) could induce pulmonary fibrosis, however, the mechanisms are still unknown."3.91TGF-β1 mediated MAPK signaling pathway promotes collagen formation induced by Nano NiO in A549 cells. ( Chang, X; Li, C; Li, S; Sun, Y; Tian, M; Zhang, Q, 2019)
"Animal studies have shown that nickel compounds may induce pulmonary fibrosis, but so far only limited documentation in humans has been available."3.72Radiographic evidence of pulmonary fibrosis and possible etiologic factors at a nickel refinery in Norway. ( Berge, SR; Skyberg, K, 2003)
"To identify pulmonary fibrosis, Masson trichrome staining, hydroxyproline content, and collagen protein expression were performed."1.46Nickel oxide nanoparticles induced pulmonary fibrosis via TGF- β1 activation in rats. ( Chang, XH; Han, AJ; Li, J; Li, S; Liu, FF; Liu, SK; Su, L; Sun, YB; Sun, YF; Sun, YY; Zhou, HH; Zhu, A; Zou, LY, 2017)
"One cause of debilitating pulmonary fibrosis is inhalation of insoluble metals."1.31Nickel-induced plasminogen activator inhibitor-1 expression inhibits the fibrinolytic activity of human airway epithelial cells. ( Andrew, A; Barchowsky, A, 2000)
"Experiments on acute and chronic inhalation of copper and nickel sulfide ore dust proved that the dust of rich ore, if compared with that of copper-bearing and impregnated ore, induces more marked toxic effects."1.30[Fibrogenic and general toxic effects of copper and nickel sulfide ore dust (data for a hygienic evaluation)]. ( Borisenkova, RV; Gvozdeva, LL; Ivanova, LG; Lutsenko, LA; Skriabin, SIu, 1997)
"This report presents the results of noncancer dose-response modeling for inhalation and oral exposures to nickel compounds using the NOAEL/LOAEL and benchmark dose (BMD) approaches."1.30Non-cancer risk assessment for nickel compounds: issues associated with dose-response modeling of inhalation and oral exposures. ( Allen, BC; Haber, LT; Kimmel, CA, 1998)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19909 (39.13)18.7374
1990's4 (17.39)18.2507
2000's2 (8.70)29.6817
2010's6 (26.09)24.3611
2020's2 (8.70)2.80

Authors

AuthorsStudies
Mo, Y1
Zhang, Y1
Wan, R1
Jiang, M1
Xu, Y1
Zhang, Q2
Zhan, H1
Chang, X2
Wang, X1
Yang, M1
Gao, Q1
Liu, H1
Li, C3
Li, S3
Sun, Y2
Wu, CH2
Hsiao, YM1
Yeh, KT1
Tsou, TC1
Chen, CY1
Wu, MF1
Ko, JL2
Yang, L1
Lin, Z1
Wang, Y1
Xu, W1
Li, Q1
Yao, W1
Song, Z1
Liu, G1
Tian, M1
Glista-Baker, EE1
Taylor, AJ1
Sayers, BC1
Thompson, EA1
Bonner, JC1
Chang, XH1
Zhu, A1
Liu, FF1
Zou, LY1
Su, L1
Liu, SK1
Zhou, HH1
Sun, YY1
Han, AJ1
Sun, YF1
Li, J1
Sun, YB1
Tang, SC1
Wang, PH1
Lee, H1
Berge, SR1
Skyberg, K1
Woźniak, H1
Muir, DC1
Julian, J1
Jadon, N1
Roberts, R1
Roos, J1
Chan, J1
Maehle, W1
Morgan, WK1
Benson, JM1
Chang, IY1
Cheng, YS1
Hahn, FF1
Kennedy, CH1
Barr, EB1
Maples, KR1
Snipes, MB1
Lutsenko, LA1
Borisenkova, RV1
Gvozdeva, LL1
Skriabin, SIu1
Ivanova, LG1
Haber, LT1
Allen, BC1
Kimmel, CA1
Andrew, A1
Barchowsky, A1
Stettler, LE2
Groth, DH1
MacKay, GR1
Proctor, JE1
Platek, SF1
Carolan, RJ1
Smith, RJ1
Donaldson, HM1
Schneider, WD1
Konetzke, GW1
Siegesmund, KA1
Funahashi, A1
Pintar, K1
Cralley, LJ1
Lainhart, WS1
Jones, JG1
Warner, CG1
Kosova, LV1
Kurennaia, SS1
Latushkina, VB1
Kochetkova, TA1
Kireev, VI1
Tolgskaia, MS1

Other Studies

23 other studies available for nickel and Alveolitis, Fibrosing

ArticleYear
miR-21 mediates nickel nanoparticle-induced pulmonary injury and fibrosis.
    Nanotoxicology, 2020, Volume: 14, Issue:9

    Topics: Animals; Cytokines; Lung; Lung Injury; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Na

2020
LncRNA MEG3 mediates nickel oxide nanoparticles-induced pulmonary fibrosis via suppressing TGF-β1 expression and epithelial-mesenchymal transition process.
    Environmental toxicology, 2021, Volume: 36, Issue:6

    Topics: Animals; Epithelial-Mesenchymal Transition; Male; Nanoparticles; Nickel; Pulmonary Fibrosis; Rats; R

2021
Upregulation of microRNA-4417 and Its Target Genes Contribute to Nickel Chloride-promoted Lung Epithelial Cell Fibrogenesis and Tumorigenesis.
    Scientific reports, 2017, 11-10, Volume: 7, Issue:1

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Lung; Lung Neopla

2017
Nickle(II) ions exacerbate bleomycin-induced pulmonary inflammation and fibrosis by activating the ROS/Akt signaling pathway.
    Environmental science and pollution research international, 2018, Volume: 25, Issue:5

    Topics: A549 Cells; Animals; Bleomycin; Cell Survival; Disease Models, Animal; Humans; Mice; Mice, Inbred C5

2018
TGF-β1 mediated MAPK signaling pathway promotes collagen formation induced by Nano NiO in A549 cells.
    Environmental toxicology, 2019, Volume: 34, Issue:6

    Topics: A549 Cells; Collagen Type I; Humans; Hydroxyproline; MAP Kinase Signaling System; Mitogen-Activated

2019
Nickel nanoparticles cause exaggerated lung and airway remodeling in mice lacking the T-box transcription factor, TBX21 (T-bet).
    Particle and fibre toxicology, 2014, Feb-06, Volume: 11

    Topics: Airway Remodeling; Animals; Antibodies, Blocking; Antibodies, Monoclonal; Bronchoalveolar Lavage Flu

2014
Nickel oxide nanoparticles induced pulmonary fibrosis via TGF- β1 activation in rats.
    Human & experimental toxicology, 2017, Volume: 36, Issue:8

    Topics: Animals; Gene Expression Regulation; Male; Metal Nanoparticles; Nickel; Pulmonary Fibrosis; Rats; Ra

2017
Nickel-induced epithelial-mesenchymal transition by reactive oxygen species generation and E-cadherin promoter hypermethylation.
    The Journal of biological chemistry, 2012, Jul-20, Volume: 287, Issue:30

    Topics: Acetylcysteine; Antigens, Differentiation; Azacitidine; Bronchi; Cadherins; Cell Line, Transformed;

2012
Radiographic evidence of pulmonary fibrosis and possible etiologic factors at a nickel refinery in Norway.
    Journal of environmental monitoring : JEM, 2003, Volume: 5, Issue:4

    Topics: Adult; Age Factors; Aged; Aged, 80 and over; Humans; Male; Middle Aged; Nickel; Norway; Occupational

2003
[Polish asbestos and its fibrogenic effect. I. Fibrous minerals in nickel ore deposits].
    Medycyna pracy, 1984, Volume: 35, Issue:6

    Topics: Animals; Asbestos; Asbestosis; Chromium; Copper; Crystallization; Iron; Mining; Nickel; Particle Siz

1984
Prevalence of small opacities in chest radiographs of nickel sinter plant workers.
    British journal of industrial medicine, 1993, Volume: 50, Issue:5

    Topics: Adult; Aged; Carcinogens; Dust; Humans; Lung; Male; Metallurgy; Middle Aged; Nickel; Occupational Di

1993
Particle clearance and histopathology in lungs of F344/N rats and B6C3F1 mice inhaling nickel oxide or nickel sulfate.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1995, Volume: 28, Issue:2

    Topics: Administration, Inhalation; Animals; Hyperplasia; Lung; Lung Diseases, Interstitial; Macrophages, Al

1995
[Fibrogenic and general toxic effects of copper and nickel sulfide ore dust (data for a hygienic evaluation)].
    Meditsina truda i promyshlennaia ekologiia, 1997, Issue:5

    Topics: Animals; Copper; Dust; Male; Maximum Allowable Concentration; Mining; Nickel; Pneumoconiosis; Pulmon

1997
Non-cancer risk assessment for nickel compounds: issues associated with dose-response modeling of inhalation and oral exposures.
    Toxicological sciences : an official journal of the Society of Toxicology, 1998, Volume: 43, Issue:2

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Humans; Inhalation Exposure; Lung;

1998
Nickel-induced plasminogen activator inhibitor-1 expression inhibits the fibrinolytic activity of human airway epithelial cells.
    Toxicology and applied pharmacology, 2000, Oct-01, Volume: 168, Issue:1

    Topics: Bronchi; Epithelial Cells; Fibrinolysis; Humans; Nickel; Plasminogen Activator Inhibitor 1; Pulmonar

2000
Identification of stainless steel welding fume particulates in human lung and environmental samples using electron probe microanalysis.
    American Industrial Hygiene Association journal, 1977, Volume: 38, Issue:2

    Topics: Air Pollutants, Occupational; Chromium; Electron Probe Microanalysis; Environmental Exposure; Filtra

1977
Fibrogenicity and carcinogenic potential of smelter slags used as abrasive blasting substitutes.
    Journal of toxicology and environmental health, 1988, Volume: 25, Issue:1

    Topics: Air Pollutants, Occupational; Animals; Copper; Dust; Environmental Exposure; Granuloma; Lung Neoplas

1988
[Comment on the contribution by B. Wiemann and L. Bergmann. "Development of bronchial cancer at the site of siderofibrosis"].
    Zeitschrift fur Erkrankungen der Atmungsorgane, 1989, Volume: 173, Issue:2

    Topics: Air Pollutants, Occupational; Carcinoma, Bronchogenic; Chromium; Humans; Lung Neoplasms; Nickel; Occ

1989
Identification of metals in lung from a patient with interstitial pneumonia.
    Archives of environmental health, 1974, Volume: 28, Issue:6

    Topics: Chromium; Cobalt; Cytological Techniques; Humans; Iron; Lung; Macrophages; Male; Metals; Methods; Mi

1974
Are trace metals associated with asbestos fibers responsible for the biologic effects attributed to asbestos?
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1973, Volume: 15, Issue:3

    Topics: Aluminum; Animals; Asbestos; Asbestosis; Chromium; Dust; Environmental Exposure; Fibrosarcoma; Human

1973
Chronic exposure to iron oxide, chromium oxide, and nickel oxide fumes of metal dressers in a steelworks.
    British journal of industrial medicine, 1972, Volume: 29, Issue:2

    Topics: Adolescent; Adult; Alloys; Chromium; Environmental Exposure; Humans; Iron; Male; Metallurgy; Middle

1972
[On the effect of oxyfers on the lung in experiments].
    Gigiena truda i professional'nye zabolevaniia, 1967, Volume: 11, Issue:6

    Topics: Animals; Bronchitis; Dust; Iron; Lung; Male; Nickel; Pneumoconiosis; Pulmonary Fibrosis; Rats; Zinc

1967
[A study of the fibrogenic action of dust formed in the processing of pig iron and nickel alloys].
    Gigiena truda i professional'nye zabolevaniia, 1969, Volume: 13, Issue:2

    Topics: Animals; Dust; Iron; Metallurgy; Nickel; Pulmonary Fibrosis; Rats; Technology

1969