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nickel and Abnormalities, Drug-Induced

nickel has been researched along with Abnormalities, Drug-Induced in 22 studies

Nickel: A trace element with the atomic symbol Ni, atomic number 28, and atomic weight 58.69. It is a cofactor of the enzyme UREASE.
nickel ion : A nickel atom having a net electric charge.
nickel atom : Chemical element (nickel group element atom) with atomic number 28.

Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.

Research Excerpts

ExcerptRelevanceReference
"The increase susceptibility of the pregnant rat to intraperitoneally administered nickel (Ni) is apparent at 12 and 19 days of pregnancy and cannot be due, therefore, to the increase in total body weight."3.67The acute toxicity and teratogenicity of nickel in pregnant rats. ( Holt, D; Mas, A; Webb, M, 1985)
"Exposure of pregnant rats to inhalation of nickel carbonyl on days 7 or 8 of gestation frequently causes the progeny to develop ocular anomalies, including anophthalmia and microphthalmia."3.66Eye malformations in rats: induction by prenatal exposure to nickel carbonyl. ( Albert, DM; Allpass, PR; Baselt, RC; Mitchell, JM; Sunderman, FW, 1979)
"Nickel carbonyl was administered to groups of pregnant hamsters by inhalation (0."1.26Teratogenicity and embryotoxicity of nickel carbonyl in Syrian hamsters. ( Allpass, PR; Reid, MC; Shen, SK; Sunderman, FW, 1980)
" The dose-response relationship was observed in all of the groups tested."1.26Congenital abnormalities in nickel poisoning in chick embryos. ( Gilani, SH; Marano, M, 1980)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199013 (59.09)18.7374
1990's6 (27.27)18.2507
2000's1 (4.55)29.6817
2010's2 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Saini, S1
Nair, N1
Saini, M1
Wang, XW1
Gu, JY1
Li, Z1
Song, YF1
Wu, WS1
Hou, YP1
Fort, DJ1
Rogers, RL1
Thomas, JH1
Hopkins, WA1
Schlekat, C1
Sunderman, FW6
Shen, SK1
Reid, MC1
Allpass, PR2
Leonard, A1
Jacquet, P1
Raithel, HJ1
Schaller, KH1
Storeng, R1
Jonsen, J1
Gilani, SH1
Marano, M1
Plowman, MC3
Kroftova, OS1
Grbac-Ivankovic, S2
Foglia, L1
Crivello, JF1
Martin, J1
Hopfer, SM2
Chashschin, VP1
Artunina, GP1
Norseth, T1
Mitchell, JM1
Baselt, RC1
Albert, DM1
Scanlon, JW1
Lu, CC1
Matsumoto, N1
Iijima, S1
Nadeenko, VG1
Lenchenko, VG1
Arkhipenko, TA1
Saĭchenko, SP1
Petrova, NN1
Sweeney, KR1
Bantle, JA1
Serafini, MT1
Romeu, A1
Anwer, J1
Mehrotra, NK1
Mas, A1
Holt, D1
Webb, M1
Scanlon, J1
Schroeder, HA1
Mitchener, M1

Reviews

4 reviews available for nickel and Abnormalities, Drug-Induced

ArticleYear
Embryotoxicity and genotoxicity of nickel.
    IARC scientific publications, 1984, Issue:53

    Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Chromosome Aberrations; Embryo Implantation; Fem

1984
[Toxicity and carcinogenicity of nickel and its compounds. A review of the current status (author's transl)].
    Zentralblatt fur Bakteriologie, Mikrobiologie und Hygiene. 1. Abt. Originale B, Hygiene, 1981, Volume: 173, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Animals; Dermatitis, Occupational; Humans; Lung Diseases; Lung Neoplasm

1981
Search for molecular mechanisms in the genotoxicity of nickel.
    Scandinavian journal of work, environment & health, 1993, Volume: 19 Suppl 1

    Topics: Abnormalities, Drug-Induced; Amino Acid Sequence; Animals; Blotting, Western; Embryo, Nonmammalian;

1993
Human fetal hazards from environmental pollution with certain non-essential trace elements.
    Clinical pediatrics, 1972, Volume: 11, Issue:3

    Topics: Abnormalities, Drug-Induced; Air Pollution; Animals; Arsenic Poisoning; Calcium; Environment; Enviro

1972

Other Studies

18 other studies available for nickel and Abnormalities, Drug-Induced

ArticleYear
Effects of gestational administration of nickel on postnatal development in Swiss albino mice.
    Human & experimental toxicology, 2014, Volume: 33, Issue:12

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Eye Abnormalities; Female; Limb Deformities, Cong

2014
Gestational age and dose influence on placental transfer of 63Ni in rats.
    Placenta, 2010, Volume: 31, Issue:4

    Topics: Abnormalities, Drug-Induced; Amniotic Fluid; Animals; Autoradiography; Bone and Bones; Extraembryoni

2010
Comparative developmental toxicity of nickel to Gastrophryne carolinensis, Bufo terrestris, and Xenopus laevis.
    Archives of environmental contamination and toxicology, 2006, Volume: 51, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Bufonidae; Embryo, Nonmammalian; Female; Growth; Hydrogen-Ion

2006
Teratogenicity and embryotoxicity of nickel carbonyl in Syrian hamsters.
    Teratogenesis, carcinogenesis, and mutagenesis, 1980, Volume: 1, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Cricetinae; Embryo, Mammalian; Female; Mesocricetus; Nickel; O

1980
Nickel toxicity in early embryogenesis in mice.
    Toxicology, 1981, Volume: 20, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Hematoma; Mice; Nickel; Pregnancy

1981
Congenital abnormalities in nickel poisoning in chick embryos.
    Archives of environmental contamination and toxicology, 1980, Volume: 9, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Chick Embryo; Nickel; Teratogens; Time Factors

1980
Effects of teratogenic exposures to Zn2+, Cd2+, Ni2+, Co2+, and Cu2+ on metallothionein and metallothionein-mRNA contents of Xenopus embryos.
    Pharmacology & toxicology, 1995, Volume: 76, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Base Sequence; Cadmium; Cobalt; Copper; Embryo, Nonmammalian;

1995
Malformations persist after metamorphosis of Xenopus laevis tadpoles exposed to Ni2+, Co2+, or Cd2+ in FETAX assays.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Cadmium; Cobalt; Metamorphosis, Biological; Nickel; Time Facto

1994
Congenital defects, abortion and other health effects in nickel refinery workers.
    The Science of the total environment, 1994, Jun-06, Volume: 148, Issue:2-3

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Cross-Sectional Studies; Female; Humans; Lung Di

1994
Eye malformations in rats: induction by prenatal exposure to nickel carbonyl.
    Science (New York, N.Y.), 1979, Feb-09, Volume: 203, Issue:4380

    Topics: Abnormalities, Drug-Induced; Animals; Anophthalmos; Carcinogens; Eye Abnormalities; Female; Gestatio

1979
Dangers to the human fetus from certain heavy metals in the environment.
    Reviews on environmental health, 1975, Volume: 2, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Arsenic Poisoning; Cadmium Poisoning; Environmental Exposure;

1975
Teratogenic effects of nickel chloride on embryonic mice and its transfer to embryonic mice.
    Teratology, 1979, Volume: 19, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Cleft Palate; Dose-Response Relationship, Drug; Female; Fetal

1979
[Embryotoxic effect of nickel entering the body via drinking water].
    Gigiena i sanitariia, 1979, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Maternal-Fetal Exchange; Nickel; Pregnanc

1979
Teratogenicity of Ni2+ in Xenopus laevis, assayed by the FETAX procedure.
    Biological trace element research, 1991, Volume: 29, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Blastocyst; Drug Evaluation, Preclinical; Embryo, Nonmammalian

1991
Nickel interactions with glutathione and related enzyme in 11-day embryo and yolk sac in rat.
    Bulletin of environmental contamination and toxicology, 1991, Volume: 47, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Embryo, Mammalian; Female; Glutathione; Nickel; Pregnancy; Rat

1991
Effect of simultaneous exposure to nickel chloride and benzo(a)pyrene on developing chick embryos.
    Drug and chemical toxicology, 1986, Volume: 9, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Benzo(a)pyrene; Chick Embryo; Drug Interactions; Embryonic and

1986
The acute toxicity and teratogenicity of nickel in pregnant rats.
    Toxicology, 1985, Volume: 35, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Female; Fetal Death; Fetal Proteins; Injections,

1985
Toxic effects of trace elements on the reproduction of mice and rats.
    Archives of environmental health, 1971, Volume: 23, Issue:2

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Arsenic; Cadmium; Diet; Female; Fetal Death; Grow

1971