Page last updated: 2024-11-01

niceritrol and Hyperlipidemias

niceritrol has been researched along with Hyperlipidemias in 13 studies

Niceritrol: An ester of nicotinic acid that lowers cholesterol and triglycerides in total plasma and in the VLD- and LD-lipoprotein fractions.

Hyperlipidemias: Conditions with excess LIPIDS in the blood.

Research Excerpts

ExcerptRelevanceReference
"The relation of plasma levels of prostaglandins to the occurrence of flushing induced by niceritrol was investigated."7.67Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing. ( Kameda, K; Kihara, S; Kubo, M; Matsuzawa, Y; Nozaki, S; Tarui, S, 1987)
" We administered niceritrol, a nicotinic acid derivative, to patients with chronic renal disease and a high serum Lp(a) level, and studied its effects on lipid metabolism, proteinuria, and renal function."5.10Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial. ( Hata, T; Owada, A; Suda, S, 2003)
"The relation of plasma levels of prostaglandins to the occurrence of flushing induced by niceritrol was investigated."3.67Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing. ( Kameda, K; Kihara, S; Kubo, M; Matsuzawa, Y; Nozaki, S; Tarui, S, 1987)
"It is recommended for patients with hyperlipemia alone, or those who suffer from combined erectile dysfunction."2.67[The clinical effect of slow releasing nicotinate on hyperlipemic impotent patients]. ( Hwang, TI; Yang, CR, 1993)
"Pentaerythritol tetranicotinate (Perycit), at an oral dosage of 750 mg daily, was given to 12 patients with idiopathic hyperlipidemia and to 12 patients with hyperlipidemia superimposed with diabetes mellitus (DM)."2.66The antilipemic effectiveness of pentaerythritol tetranicotinate on hyperlipidemic patients with or without diabetes mellitus--a double-blind, randomized and two-period change-over experiment. ( Chen, JJ; Chen, RL; Chern, JC; Ho, LT; Hsu, SC; Jap, TS; Kwok, CF; Wu, MS, 1985)
" Nicotinic acid in the form of niceritrol had another type of dose-response in type II with doses from 3 to 6 g/day."1.25Cholestyramine, clofibrate and nicotinic acid as single or combined treatment of type IIa and IIb hyperlipoproteinaemia. ( Carlson, LA; Olsson, AG; Orö, L; Rössner, S, 1975)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19907 (53.85)18.7374
1990's4 (30.77)18.2507
2000's2 (15.38)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Owada, A1
Suda, S1
Hata, T1
Fujioka, T1
Ueno, T1
Matsumoto, T1
Watanabe, H1
Hwang, TI1
Yang, CR1
Teramoto, T1
Yamada, N1
Shimano, H1
Oka, Y1
Itakura, H2
Saito, Y1
Morisaki, N1
Shirai, K1
Ishikawa, T1
Tada, N1
Ito, H1
Yamanouchi, T1
Matsushima, T1
Kawakami, M1
Murase, T1
Okubo, M1
Totsuka, Y1
Kikuchi, M1
Britov, AN1
Shmushkovich, BI1
Karmanskiĭ, IM1
Orö, L2
Olsson, AG2
Rössner, S2
Carlson, LA1
Lundholm, L1
Jacobsson, L1
Brattsand, R1
Magnusson, O1
Hansen, PF1
Mimura, K1
Yukawa, S1
Nozaki, S1
Kihara, S1
Kubo, M1
Kameda, K1
Matsuzawa, Y1
Tarui, S1
Ho, LT1
Chern, JC1
Hsu, SC1
Chen, RL1
Kwok, CF1
Wu, MS1
Chen, JJ1
Jap, TS1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized, Double-blind, Placebo-controlled Trial of Niaspan® in Patients With Overt Diabetic Nephropathy and Moderate Renal Impairment[NCT00108485]Phase 39 participants (Actual)Interventional2005-04-30Terminated (stopped due to Unable to recruit sufficient study subjects)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Change in Proteinuria

(NCT00108485)
Timeframe: Baseline, 1 year

Interventionmg/dL (Number)
Extended Release Niacin42
Placebo63

Reviews

1 review available for niceritrol and Hyperlipidemias

ArticleYear
[Dyslipidemia in renal failure].
    Nihon rinsho. Japanese journal of clinical medicine, 2004, Volume: 62 Suppl 6

    Topics: Arteriosclerosis; Cerebrovascular Disorders; Cholesterol, HDL; Cholesterol, LDL; Clofibrate; Coronar

2004

Trials

4 trials available for niceritrol and Hyperlipidemias

ArticleYear
Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial.
    The American journal of medicine, 2003, Apr-01, Volume: 114, Issue:5

    Topics: Chronic Disease; Creatinine; Disease Progression; Female; Humans; Hyperlipidemias; Hypolipidemic Age

2003
[The clinical effect of slow releasing nicotinate on hyperlipemic impotent patients].
    Zhonghua yi xue za zhi = Chinese medical journal; Free China ed, 1993, Volume: 52, Issue:4

    Topics: Delayed-Action Preparations; Erectile Dysfunction; Humans; Hyperlipidemias; Male; Niceritrol; Single

1993
The effects of different dose regimens of niceritrol of serum lipid concentrations in man.
    Acta medica Scandinavica, 1976, Volume: 200, Issue:4

    Topics: Administration, Oral; Cholesterol; Delayed-Action Preparations; Dose-Response Relationship, Drug; Hu

1976
The antilipemic effectiveness of pentaerythritol tetranicotinate on hyperlipidemic patients with or without diabetes mellitus--a double-blind, randomized and two-period change-over experiment.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1985, Volume: 9, Issue:1

    Topics: Clinical Trials as Topic; Diabetes Complications; Double-Blind Method; Humans; Hyperlipidemias; Nice

1985

Other Studies

8 other studies available for niceritrol and Hyperlipidemias

ArticleYear
Dose-dependent effect of niceritrol on plasma lipoprotein-a.
    Scandinavian journal of clinical and laboratory investigation, 1996, Volume: 56, Issue:4

    Topics: Aged; Dose-Response Relationship, Drug; Female; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipop

1996
[Treatment of ischemic heart disease with a hypolipoproteinemic drug pericit].
    Kardiologiia, 1977, Volume: 17, Issue:6

    Topics: Adult; Aged; Cholesterol; Coronary Disease; Drug Evaluation; Female; Humans; Hyperlipidemias; Lipopr

1977
Cholestyramine, clofibrate and nicotinic acid as single or combined treatment of type IIa and IIb hyperlipoproteinaemia.
    Postgraduate medical journal, 1975, Volume: 51, Issue:8

    Topics: Cholestyramine Resin; Clofibrate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Human

1975
Influence of nicotinic acid, niceritrol and beta-pyridylcarbinol on experimental hyperlipidemia and atherosclerosis in mini-pigs.
    Atherosclerosis, 1978, Volume: 29, Issue:2

    Topics: Animals; Aorta; Arteriosclerosis; Cholesterol; Coronary Vessels; Humans; Hyperlipidemias; Lipoprotei

1978
Differential drug therapy of the hyperlipoproteinaemias. The efficacy of lipid lowering drugs alone and in combination.
    Postgraduate medical journal, 1975, Volume: 51, Issue:8

    Topics: Cholesterol; Clofibrate; Drug Synergism; Drug Therapy, Combination; Humans; Hyperlipidemias; Hypolip

1975
[Treatment of hyperlipidemia].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1992, Nov-10, Volume: 81, Issue:11

    Topics: Blood Component Removal; Cholesterol, LDL; Cholestyramine Resin; Clofibrate; Coronary Disease; Dieta

1992
[Hyperlipidemia and drug treatment].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Arteriosclerosis; Carnitine; Cholestyramine Resin; Glomerulonephritis; Humans; Hyperlipidemias; Kidn

1991
Increased compliance of niceritrol treatment by addition of aspirin: relationship between changes in prostaglandins and skin flushing.
    International journal of clinical pharmacology, therapy, and toxicology, 1987, Volume: 25, Issue:12

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Aspirin; Cholesterol; Dinoprostone; Flushing; Humans; Hyp

1987