nicergoline and Alzheimer Disease

nicergoline has been researched along with Alzheimer Disease in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's6 (42.86)18.2507
2000's2 (14.29)29.6817
2010's3 (21.43)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Bogolepova, AN1
Abe, K; Hishikawa, N; Matsumoto, N; Nomura, E; Ohta, Y; Omote, Y; Sasaki, R; Tadokoro, K; Takemoto, M; Tsunoda, K; Yamashita, T1
Weinstein, JD1
Chen, L; Fang, L; Wang, C; Zang, G1
Damulin, IV1
Battaglia, A; Battaglia, G; Bosco, P; Calafiore, M; Canonico, PL; Caraci, F; Chisari, M; Copani, A; Frasca, G; Nicoletti, F; Sortino, MA1
Anderer, P; Grünberger, J; Linzmayer, L; Neuhold, A; Paulus, E; Podreka, I; Saletu, B; Semlitsch, HV; Wicke, L1
Winblad, B1
Crook, TH1
Anderer, P; Saletu, B; Semlitsch, HV1
Flynn, BL; Ranno, AE1
Gavrilova, SI; Zharikov, GA1
Arnetoli, G; Battaglia, A; Grignani, A; Paganini, M; Sacchetti, G; Versari, A; Zappoli, R1

Reviews

3 review(s) available for nicergoline and Alzheimer Disease

ArticleYear
[Dementia and small vessel diseases of the brain].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:8

    Topics: Alzheimer Disease; Brain; Cerebral Small Vessel Diseases; Dementia, Vascular; Humans; Neuroimaging; Nicergoline; Risk Factors

2014
Pharmacologic management of Alzheimer disease, Part II: Antioxidants, antihypertensives, and ergoloid derivatives.
    The Annals of pharmacotherapy, 1999, Volume: 33, Issue:2

    Topics: Alzheimer Disease; Antihypertensive Agents; Antioxidants; Drugs, Investigational; Ergoloid Mesylates; Humans; Nicergoline; Nootropic Agents

1999
[Current strategies of pathogenetic therapy of Alzheimer's disease].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2001, Issue:7

    Topics: Aged; Alzheimer Disease; Amino Acids; Aminoquinolines; Carbamates; Cholinesterase Inhibitors; Clinical Trials as Topic; Donepezil; Dopamine Agents; Estrogens; Ginkgo biloba; Humans; Indans; Memantine; Monoamine Oxidase Inhibitors; Multicenter Studies as Topic; Neuronal Plasticity; Neuroprotective Agents; Neurotransmitter Agents; Nicergoline; Nootropic Agents; Phenylcarbamates; Phytotherapy; Piperidines; Piracetam; Pyrithioxin; Rivastigmine; Selegiline; Tacrine; Time Factors

2001

Trials

4 trial(s) available for nicergoline and Alzheimer Disease

ArticleYear
The Efficacy of Sertraline, Escitalopram, and Nicergoline in the Treatment of Depression and Apathy in Alzheimer's Disease: The Okayama Depression and Apathy Project (ODAP).
    Journal of Alzheimer's disease : JAD, 2020, Volume: 76, Issue:2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antidepressive Agents; Apathy; Citalopram; Depression; Female; Humans; Male; Nicergoline; Nootropic Agents; Prospective Studies; Sertraline; Single-Blind Method; Treatment Outcome

2020
Nicergoline in senile dementia of Alzheimer type and multi-infarct dementia: a double-blind, placebo-controlled, clinical and EEG/ERP mapping study.
    Psychopharmacology, 1995, Volume: 117, Issue:4

    Topics: Alzheimer Disease; Brain; Brain Mapping; Dementia, Multi-Infarct; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Humans; Male; Nicergoline; Psychiatric Status Rating Scales

1995
Relations between symptomatology and brain function in dementias: double-blind, placebo-controlled, clinical and EEG/ERP mapping studies with nicergoline.
    Dementia and geriatric cognitive disorders, 1997, Volume: 8 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Mapping; Dementia, Multi-Infarct; Double-Blind Method; Electroencephalography; Evoked Potentials, Auditory; Female; Humans; Male; Mental Status Schedule; Nicergoline

1997
Contingent negative variation and reaction time in patients with presenile idiopathic cognitive decline and presenile Alzheimer-type dementia. Preliminary report on long-term nicergoline treatment.
    Neuropsychobiology, 1987, Volume: 18, Issue:3

    Topics: Alzheimer Disease; Cognition Disorders; Contingent Negative Variation; Double-Blind Method; Electroencephalography; Electrophysiology; Ergolines; Female; Humans; Male; Middle Aged; Nicergoline; Reaction Time

1987

Other Studies

7 other study(ies) available for nicergoline and Alzheimer Disease

ArticleYear
[Vascular cognitive impairment].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2022, Volume: 122, Issue:10

    Topics: Alzheimer Disease; Cholinergic Agents; Cognitive Dysfunction; Dementia, Vascular; Humans; Nicergoline; Stroke

2022
A unique and promising combination of medications for the treatment of Alzheimer's disease.
    Medical hypotheses, 2017, Volume: 109

    Topics: Alzheimer Disease; Brain; Dementia; Disease Progression; Drug Design; Drug Therapy, Combination; Humans; Inflammation; Methylene Blue; Neurons; Nicergoline; Oxidative Stress; Pentoxifylline; Pyridoxamine; Pyrimidines

2017
Ameliorative effect of nicergoline on cognitive function through the PI3K/AKT signaling pathway in mouse models of Alzheimer's disease.
    Molecular medicine reports, 2018, Volume: 17, Issue:5

    Topics: Alzheimer Disease; Animals; Cognition; Disease Models, Animal; Hippocampus; Male; Mice; Neurogenesis; Neuroprotective Agents; Nicergoline; Nootropic Agents; Phosphatidylinositol 3-Kinase; Proto-Oncogene Proteins c-akt; Signal Transduction

2018
Nicergoline, a drug used for age-dependent cognitive impairment, protects cultured neurons against beta-amyloid toxicity.
    Brain research, 2005, Jun-14, Volume: 1047, Issue:1

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Apoptosis; Astrocytes; bcl-2-Associated X Protein; Cell Communication; Cells, Cultured; Cerebral Cortex; Coculture Techniques; Cognition Disorders; Memory Disorders; Nerve Growth Factors; Neurons; Neuroprotective Agents; Nicergoline; Peptide Fragments; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley

2005
[Therapy of primary dementia based on modern concepts].
    Der Nervenarzt, 1995, Volume: 66, Issue:5 Suppl

    Topics: Adrenergic alpha-Antagonists; Alzheimer Disease; Dementia; Dementia, Multi-Infarct; Humans; Nicergoline

1995
Altered neurotransmission and signal transduction: targets for nicergoline treatment.
    Dementia and geriatric cognitive disorders, 1997, Volume: 8 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Alzheimer Disease; Cyclic AMP; Humans; Neurotransmitter Agents; Nicergoline; Signal Transduction

1997
Nicergoline: parallel evolution of clinical trial methodology and drug development in dementias.
    Dementia and geriatric cognitive disorders, 1997, Volume: 8 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Alzheimer Disease; Clinical Trials as Topic; Dementia; Drug Evaluation; Humans; Mental Status Schedule; Nicergoline; Treatment Outcome

1997