nicardipine has been researched along with Uremia in 2 studies
Nicardipine: A potent calcium channel blockader with marked vasodilator action. It has antihypertensive properties and is effective in the treatment of angina and coronary spasms without showing cardiodepressant effects. It has also been used in the treatment of asthma and enhances the action of specific antineoplastic agents.
nicardipine : A racemate comprising equimolar amounts of (R)- and (S)-nicardipine. It is a calcium channel blocker which is used to treat hypertension.
2-[benzyl(methyl)amino]ethyl methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate : A dihydropyridine that is 1,4-dihydropyridine substituted by a methyl, {2-[benzyl(methyl)amino]ethoxy}carbonyl, 3-nitrophenyl, methoxycarbonyl and methyl groups at positions 2, 3, 4, 5 and 6, respectively.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In comparison to the patients with normal renal function, there were significant increases in AUC and Cmax in the patients with renal impairment." | 1.28 | Inhibitory effect of uraemia on the hepatic clearance and metabolism of nicardipine. ( Ahmed, JH; Elliott, HL; Grant, AC; Murray, GR; Rodger, RS, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Owada, A | 1 |
| Saito, H | 1 |
| Mochizuki, T | 1 |
| Tanaka, M | 1 |
| Otsuka, M | 1 |
| Yokoyama, Y | 1 |
| Fukuda, S | 1 |
| Ahmed, JH | 1 |
| Grant, AC | 1 |
| Rodger, RS | 1 |
| Murray, GR | 1 |
| Elliott, HL | 1 |
2 other studies available for nicardipine and Uremia
| Article | Year |
|---|---|
Radial arterial spasm in uremic patients undergoing construction of arteriovenous hemodialysis fistulas: diagnosis and prophylaxis with intravenous nicardipine.
Topics: Adult; Aged; Aged, 80 and over; Arteriovenous Shunt, Surgical; Female; Humans; Injections, Intraveno | 1993 |
Inhibitory effect of uraemia on the hepatic clearance and metabolism of nicardipine.
Topics: Administration, Oral; Adult; Biological Availability; Blood Pressure; Glomerular Filtration Rate; He | 1991 |